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Journal articles on the topic 'HYPERTENSIVE DRUGS'

Author: Grafiati

Published: 11 September 2023

Last updated: 25 July 2025

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1

Wilson, J., M. A. Orchard, A. A. Spencer, J. A. Davies, and C. R. M. Prentice. "Anti-Hypertensive Drugs Non-Specifically Reduce “Spontaneous” Activation of Blood Platelets." Thrombosis and Haemostasis 62, no. 02 (1989): 776–80. http://dx.doi.org/10.1055/s-0038-1646901.

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SummaryAbnormal activation of blood platelets may be a contributory factor in the accelerated vascular disease which occurs in hypertension. We investigated the effects of lowering blood pressure in 12 patients with mild hypertension on several aspects of platelet function, initially in a placebo-controlled, double-blind, crossover study with nisoldipine, and subsequently in the same patients comparing nisoldipine with the patients’ usual anti-hypertensive therapy. Values were compared with those from an age, sex-matched control population. Seven hypertensive patients with renal failure were a

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O'Collins, Victoria E., Geoffrey A. Donnan, Malcolm R. Macleod, and David W. Howells. "Hypertension and Experimental Stroke Therapies." Journal of Cerebral Blood Flow & Metabolism 33, no. 8 (2013): 1141–47. http://dx.doi.org/10.1038/jcbfm.2013.88.

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Hypertension is an established target for long-term stroke prevention but procedures for management of hypertension in acute stroke are less certain. Here, we analyze basic science data to examine the impact of hypertension on candidate stroke therapies and of anti-hypertensive treatments on stroke outcome. Methods: Data were pooled from 3,288 acute ischemic stroke experiments (47,899 animals) testing the effect of therapies on infarct size (published 1978-2010). Data were combined using meta-analysis and meta-regression, partitioned on the basis of hypertension, stroke model, and therapy. Res

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Wang, Jiwu. "History of Development, Classification, Mechanism of Action and Rational Application of Major Anti-Hypertensive Drugs." International Journal of Public Health and Medical Research 1, no. 2 (2024): 44–52. http://dx.doi.org/10.62051/ijphmr.v1n2.07.

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With the rise of the aging population, the number of people with high blood pressure is increasing. Hypertension can cause cerebral hemorrhage, cerebral infarction, heart failure, coronary atherosclerotic heart disease and renal failure. One of the most common treatments for hypertension is drug therapy. Common anti-hypertensive drugs include angioplasty-converting enzyme inhibitors, calcium channel blockers, adrenergic receptor antagonists, diuretics, central anti-hypertensive drugs and vasodilation. The types of drugs used vary depending on the individual's condition. This article reviews th

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Bhandary, Apeksha, and Prasan R. Bhandari. "Drug usage pattern of anti-hypertensive drugs in elderly diabetic, hypertensive in-patients with or without impaired renal function in a tertiary care hospital." International Journal of Basic & Clinical Pharmacology 7, no. 4 (2018): 696. http://dx.doi.org/10.18203/2319-2003.ijbcp20181172.

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Background: Hypertension (HTN) and Diabetes mellitus (DM) are the leading contributors to the cardiovascular mortality and morbidity. Drug utilisation studies (DUS) are potential tools in the evaluation in health care systems. Objectives was to analyse the drug usage pattern of anti-hypertensives in elderly hypertensive diabetic in-patients in a tertiary hospital. To analyse drug usage pattern of anti-hypertensives in elderly hypertensive, diabetic in-patients with renal impairment in a tertiary hospital.Methods: The study population consisted of 165 hypertensive diabetic in-patients at Shri D

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Risna, Amalia, Jauhar Latifah, Linda Permata Sari, Ronalisa Ronalisa, Henny Maryani, and Difa Intannia. "PROFIL PERESEPAN PENGGUNAAN ANTIHIPERTENSI PADA PASIEN RAWAT JALAN DI PUSKESMAS SUNGAI ULIN PERIODE OKTOBER 2020." Jurnal Insan Farmasi Indonesia 5, no. 1 (2022): 8–15. http://dx.doi.org/10.36387/jifi.v5i1.913.

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Hypertension is a disease that often causes death because many people do not realize it. People have hypertension if the blood pressure above 140/90 mmHg after regular checking. In Sungai Ulin Public health center, hypertension is the second-highest disease. The study aimed to determine the characteristics of hypertensive patients and the profile of prescribing the use of anti-hypertensive drugs in outpatients in the period October 2020 at Sungai Ulin Public health center. This research is an observational descriptive study using retrospective data with the inclusion criteria. A population of

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Aryunadi, Yudha Fahmi, Ahmad Azrul Zuniarto, Fitri Zakiah, and Anggun Marselina Hermawan. "Effectiveness and Monitoring of Side Effects of Hypertension Drugs in the Elderly in Kalijaga Village." Saudi Journal of Medical and Pharmaceutical Sciences 10, no. 11 (2024): 855–62. https://doi.org/10.36348/sjmps.2024.v10i11.011.

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Hypertension is the disease with the highest prevalence in Indonesia. Prevalence of hypertension in the elderly aged 55-75 years and above, which is 62.63% of the overall percentage of people with hypertension. However, many elderly people are not aware and responsive to the treatment of hypertension. The use of anti-hypertensive drugs is often not taken with good procedures. The purpose of this study was to determine the effectiveness and side effects of anti-hypertensive drugs consumed by the elderly in Kalijaga. Sampling using purposive sampling technique with a sample of 30 respondents wit

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Jaryal, Ajay, Bhupender Kumar, Nripen Gaur, Kapil Sharma, Sanjay Vikrant, and Nitin Kumar. "Prevalence of hypertension-mediated target organ damage in hypertensive patients in an outpatient setting – An observational study." International Journal of Noncommunicable Diseases 10, no. 1 (2025): 12–16. https://doi.org/10.4103/jncd.jncd_51_24.

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ABSTRACT Aim: We aimed to study the clinical profile of hypertensive patients in an outpatient setting and to assess the burden and pattern of hypertension-mediated target organ damage (HMOD). Materials and Methods: A prospective observational study evaluated the clinical profile of hypertensive patients who attended a general internal medicine outpatient clinic over 1 year from April 2022 to March 2023. Results: A total of 454 patients (64.5% – preexisting hypertension, 35.5% – newly diagnosed) were found hypertensive during outpatient visits during the study period. About 22.7% had symptoms

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Cífková, Renata. "Antiplatelet and Lipid-lowering Drugs in Hypertension." European Cardiology Review 9, no. 1 (2014): 16. http://dx.doi.org/10.15420/ecr.2014.9.1.16.

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Antiplatelet therapy, and low-dose acetylsalicylic acid (ASA) in particular, is recommended in hypertensive patients with previous cardiovascular events and is considered in hypertensive patients with reduced renal function or a high cardiovascular (CV) risk, provided blood pressure is well-controlled. Acetylsalicylic acid is not recommended in low-to-moderate risk hypertensive patients in whom absolute benefit and harm are equivalent. Further trials evaluating antithrombotic therapy including newer agents in hypertension are needed. Women at high and moderate risk of pre-eclampsia are advised

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Ullah, Mohammad, Suman Kumar Saha, Md Toufiqur Rahman, Md Abdul Karim, and Rashid Ahmed. "Nonadherence to Drugs among the Hypertensive Patients in Outpatient Department of a Secondary Hospital of Bangladesh." Cardiovascular Journal 11, no. 2 (2019): 105–13. http://dx.doi.org/10.3329/cardio.v11i2.40409.

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Background: One fifth Bangladeshi adults are hypertensive. Forty percent of them know that they are hypertensive. 53% to 75% hypertensive people have got uncontrolled hypertension. One of the most important causes of uncontrolled hypertension is nonadherence to drugs. We tried to find the causes of non adherence of drugs among the patients with HTN in a secondary care hospital of Bangladesh. Methods: The study was conducted from March 2018 to June 2018. Total 144 patients with HTN were included in the study. Taking drugs in less than 80% of the days of previous six months was defined as

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Rajak, Devraj, Deepali Sahu, Anushree Jain, et al. "Review on Toxicity of Antihypertensive Drugs." Asian Journal of Dental and Health Sciences 2, no. 4 (2022): 64–68. http://dx.doi.org/10.22270/ajdhs.v2i4.28.

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Adverse drug reactions are common and pose a serious health problem, limiting treatment options, causing compliance issues, and even leading to therapy discontinuation. Hypertension is a chronic disease that is regarded as a major risk factor for cardiovascular disease. To achieve a target blood pressure in an individual patient, a wide range of anti-hypertensive agents are available as single or combination therapy, whereas combination therapy increases the risk of developing Adverse Drug Reaction. Hypertensive patients frequently have coexisting disease conditions such as hyperlipidemia, imp

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Riungu, Dianah Kathambi, and Patrick Mbataru. "Determinants of Accessibility of Hypertensive Drugs by Adult Patients Under Sustainable Development Goal Three in Nairobi City County, Kenya." International Journal of Current Aspects 5, no. 4 (2021): 108–19. http://dx.doi.org/10.35942/ijcab.v5i4.214.

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Hypertension is noted to be the easiest non-communicable disease to diagnose treat and monitor if proper health systems are put in place to ensure hypertensive drugs are accessible to hypertensive patients who need them daily. It is estimated that prevalence rate of hypertension in Kenya range from 13 % to 50 % and only 1 in 5 of the diagnosed are on hypertensive medicines. Lack of medication intake leads to uncontrolled hypertension resulting to more serious health complications which result to premature deaths. Previous studies have provided little information on the determinants of hyperten

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Paudel, Gita, Sirisa Karki, Karma Murti Bhurtyal, and Lokeshwar Chaurasia. "Prescription pattern of anti-hypertensive drugs in Chitwan Medical College Hospital." Janaki Medical College Journal of Medical Science 9, no. 1 (2021): 41–46. http://dx.doi.org/10.3126/jmcjms.v9i1.38325.

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Background and Objectives: Hypertension is a crucial health issue globally. Cardiovascular and kidney disease is one of the results of hypertension which remarkably confer to overall mortality. Thus, the aim of this study is to investigate the prescribing pattern of anti-hypertensive drugs to hypertensive patients and also to establish the current trend of prescribing pattern of anti-hypertensive drugs at Chitwan Medical College (CMC). Material and Methods: A descriptive cross-sectional study was conducted among 290 patients to assess the prescribing pattern of anti-hypertensive drugs fr

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Makó, Katalin, Corina Ureche, and Zsuzsanna Jeremiás. "An Updated Review of Hypertensive Emergencies and Urgencies." Journal Of Cardiovascular Emergencies 4, no. 2 (2018): 73–83. http://dx.doi.org/10.2478/jce-2018-0013.

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Abstract A hypertensive crisis is an abrupt and severe rise in the arterial blood pressure (BP) occurring either in patients with known essential or secondary hypertension, or it may develop spontaneously. The most frequent cause for the severe and sudden increase in BP is inadequate dosing or stopping antihypertensive treatment in hypertensive patients. Severe hypertension can be defined as either a hypertensive emergency or an urgency, depending on the existence of organ damage. In hypertensive urgencies, there are no signs of acute end-organ damage, and orally administered drugs might be su

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Walker, James Johnston. "Hypertensive Drugs in Pregnancy." Clinics in Perinatology 18, no. 4 (1991): 845–73. http://dx.doi.org/10.1016/s0095-5108(18)30499-8.

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Brubaker, R. F. "Ocular hypertensive drugs—Overview." Experimental Eye Research 55 (September 1992): 185. http://dx.doi.org/10.1016/0014-4835(92)90845-j.

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Gupta, Rohini, Apoorva Malhotra, and Pavan Malhotra. "Study of prescribing pattern of drugs used in the treatment of hypertension in a tertiary care teaching hospital in North India: an observational study." International Journal of Research in Medical Sciences 6, no. 7 (2018): 2380. http://dx.doi.org/10.18203/2320-6012.ijrms20182821.

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Background: Hypertension is one of the most common chronic diseases leading to high mortality and morbidity. In order to prevent complications and to improve the patient survival, the early and efficient management of essential hypertension is very much needed. In this context, the use of established anti-hypertensives assumes paramount importance. Objective was to study the prescribing pattern of anti-hypertensive drugs in a tertiary care teaching hospital in north India.Methods: It was a cross-sectional observational study involving 205 prescriptions for patients suffering from primary essen

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Xalilov, Nizomiddin, Temur Jurakulov, Gyosiddin Xursandov, Xumoyun Nematov, and Jonibek Safarov. "MODERN EMERGENCY CARE STRATEGY FOR HYPERTONIC CRISIS." UZBEK MEDICAL JOURNAL Special issue, no. 2 (2021): 9–18. http://dx.doi.org/10.26739/2181-0664-2021-si-2-2.

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The article is devoted to discussing modern approaches todiagnosis andtreatment in complicated anduncomplicated hypertensive crises.The options for antihypertensive drugs are considereddepending on thenature of target organ damage ina hypertensive crisis.The data on themost frequently prescribed drugs for complicated anduncomplicated hypertensive crisis increases the volumetric velocity of coronary andcerebral blood flowand reduces the pressure inthe pulmonary artery system.It is usually used to relieve the mild uncomplicated hypertensive crisis. Still, a wide range of side effects, including

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Xalilov, Nizomiddin, Temur Jurakulov, Gyosiddin Xursandov, Xumoyun Nematov, and Jonibek Safarov. "MODERN EMERGENCY CARE STRATEGY FOR HYPERTONIC CRISIS." UZBEK MEDICAL JOURNAL Special issue, no. 2 (2021): 9–18. http://dx.doi.org/10.26739/2181-0664-2021-si-2-2.

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The article is devoted to discussing modern approaches todiagnosis andtreatment in complicated anduncomplicated hypertensive crises.The options for antihypertensive drugs are considereddepending on thenature of target organ damage ina hypertensive crisis.The data on themost frequently prescribed drugs for complicated anduncomplicated hypertensive crisis increases the volumetric velocity of coronary andcerebral blood flowand reduces the pressure inthe pulmonary artery system.It is usually used to relieve the mild uncomplicated hypertensive crisis. Still, a wide range of side effects, including

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Chelo, Herman Ngadjole, Théophile Kabesha Barhwamire, Patricia Lukusa Mishika, Zacharie Kibendelwa Tsongo, and Stanis Okitotsho Wembonyama. "Prevalence and associated factors of uncontrolled hypertension in hypertensive patients in the city of Goma, DRC." Advances in General Practice of Medicine 5, no. 1 (2023): 74–80. http://dx.doi.org/10.25082/agpm.2023.01.001.

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Background: The objectives of this study were to determine the proportion of uncontrolled hypertension in hypertensive patients followed up on an outpatient basis and to investigate the factors associated with this poor control. Methods: This was a cross-sectional analytical study of 167 hypertensive patients followed in eight health facilities in Goma city. Uncontrolled hypertension was defined as systolic blood pressure (SBP) ≥140 mmHg and/or diastolic blood pressure (DBP) ≥90 mmHg. Results: The proportion of uncontrolled hypertension was 95.2%. In bivariate analysis, no factor was associate

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Jadhav, Rahul B., and Deepali D. Wagh. "Comparative Study of Anti-Hypertensive Drugs (Beta-Blockers)." International Journal of Research Publication and Reviews 6, no. 5 (2025): 17333–37. https://doi.org/10.55248/gengpi.6.0525.19115.

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Hatamipour Dehno, Safura, Simin Taghavi, and Nayyereh Ayati. "Correlation Between Divided Doses of Chronic Antihypertensive Drugs and Pregnancy Outcomes." International Journal of Women's Health and Reproduction Sciences 8, no. 3 (2017): 328–32. http://dx.doi.org/10.15296/ijwhr.2020.52.

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Objectives: Hypertension, as a common problem during pregnancy, is a major cause of maternal and fetal morbidity and mortality. Anti-hypertensive drugs are used to prolong the pregnancy or modify perinatal outcomes in pregnant women with hypertensive disorders. Severe monitoring of blood pressure is subsequently essential in these mothers. The aim of this study was to evaluate the correlation between divided doses of chronic hypertensive drugs and the end of pregnancy in mothers with gestational hypertension. Materials and Methods: In this prospective research, 99 pregnant women with chronic h

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Hidayah, Himyatul. "EVALUASI RASIONALITAS PENGGUNAAN OBAT ANTIHIPERTENSI TERHADAP PASIEN HIPERTENSI DI RSUD KARAWANG." Jurnal Buana Farma 3, no. 1 (2023): 7–13. http://dx.doi.org/10.36805/jbf.v3i1.775.

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Hypertension is a disease characterized by an increase in systolic blood pressure of more than 140 mmHg and diastolic blood pressure of more than 90 mmHg on two measurements, with an interval of five minutes in a state of sufficient rest/calm. This study aims to determine the relationship between hypertension and the patient's gender and age on the incidence of hypertension and the rationality of using antihypertensive drugs in hypertensive patients at the Karawang Hospital Outpatient Installation in 2019. This research is an observational study with a cross-sectional descriptive analysis desi

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Aly, Nur Islahuddin, and Annik Megawati. "HUBUNGAN TINGKAT KEPATUHAN MINUM OBAT ANTIHIPERTENSI DAN OBESITAS TERHADAP TEKANAN DARAH PENDERITA HIPERTENSI." Cendekia Journal of Pharmacy 7, no. 2 (2023): 187–95. https://doi.org/10.31596/cjp.v7i2.250.

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Hypertension is the most common disease that affects around 40% of the adult population worldwide and is called the silent killer. Compliance with taking prescription drugs is very necessary to avoid the risk of complications and minimize medical expenses. Improved adherence will provide maximum benefit from the prescribed medication and this is one simple strategy in the management of hypertension. Non- compliance with the use of anti-hypertensive drugs and obesity will be detrimental to the patient itself and is a factor that causes the failure of therapy being undertaken. The purpose of thi

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Hikmayani, A. A., and Y. P. Rachmawan. "11. Treatment Profiles of Hypertensive Patients at a Private Hospital in Cirebon." Journal of Hypertension 42, Suppl 2 (2024): e3. http://dx.doi.org/10.1097/01.hjh.0001026824.02132.0b.

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Background: Hypertension is one of the most widely prevalent cardiovascular disorders in the world, affecting 1.28 billion adults, of whom two-thirds live in low- and middle-income countries. Objectives: To assess the distribution of hypertensive patients receiving monotherapy, dual combination, and triple combination antihypertensive medication and its comorbidities. Methods: This descriptive analytic study was conducted from November 2022 to November 2023. This study included adult hypertensive patients (age ≥18 years) treated with one or more antihypertensive medications. The hospital infor

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Dole, Radhika, Daniel Kothapally, Sampoorna Chukkala, and Ravi Chander Thatipelli. "Approaches to Improve Oral Bioavailability of Antihypertensive Drugs: A Mini-Review." Journal of Drug Delivery and Therapeutics 13, no. 5 (2023): 73–77. http://dx.doi.org/10.22270/jddt.v13i5.5814.

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Hypertension elevates the risk of heart disease and stroke which are one of the most frequent causes of death. Fortunately, hypertension is manageable with the use of anti-hypertensives and a healthy lifestyle. However, patient non-adherence to the prescribed dosing regimen is the primary reason for uncontrolled blood pressure levels. Daily multiple doses of medication are one of the major reasons for patient non-compliance to the dosing regimen. Multiple doses of medication are a result of low solubility and high first-pass metabolism of anti-hypertensives. There are several approaches to imp

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Sudrajat, Ace, Ainina Ayu Rahmadani, Suratun, et al. "Correlation of Knowledge and Family Support with Treatment Compliance of Tuberculosis Sufferers." AACENDIKIA: Journal of Nursing 2, no. 2 (2023): 61–69. http://dx.doi.org/10.59183/aacendikiajon.v2i2.25.

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Introduction: The Hypertension is a cardiovascular disease characterized by increased blood pressure. Pharmacological and non-pharmacological therapies are one of the factors that can control hypertension. Pharmacological therapy involves the use of drugs which is the basis of a person's compliance with treatment. Adherence in taking medication also has factors that can influence such as knowledge, family support, access to health services. Knowing the relationship between knowledge and family support with adherence to taking anti-hypertensive drugs in hypertensive patients at the Matraman Dis

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Belayachi, Safae, Fatima Zahra Boukhari, Firdaous Essayagh, et al. "Non-adherence to antihypertensive drugs and its risk factors among hypertensive patients, Marrakech, Morocco." PLOS Global Public Health 4, no. 8 (2024): e0002774. http://dx.doi.org/10.1371/journal.pgph.0002774.

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Non-adherence to hypertensive drugs is a barrier to controlling blood pressure and decreases hypertensive patients’ quality of life. The aim of this study was to determine the prevalence of non-adherence to hypertensive drugs among hypertensive patients treated at Marrakech’s primary health care facilities. A cross-sectional survey of 922 hypertensive patients treated at Marrakech’s primary health care facilities for arterial hypertension was conducted between 2021 and 2022. For collecting data, two questionnaires were employed. One was administered during an interview to patients and focused

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Purnawinadi, I. Gede, and Irene Jessica Lintang. "RELATIONSHIP OF FAMILY SUPPORT WITH ADHERENCE TO TAKING MEDICATION AMONG HYPERTENSIVE PATIENTS." Jurnal Skolastik Keperawatan 6, no. 1 (2020): 35–41. http://dx.doi.org/10.35974/jsk.v6i1.2248.

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ABSTRACT Introduction: Hypertension requires lifelong treatment. One influence of the successful treatment of hypertensive patients is adherence to taking drugs through family support roles. Purpose: This study identified the relationship between family support and adherence to taking medication for hypertensive patients at the Airmadidi Health Center in North Minahasa Regency. Method: This study was an observational analytic with cross-sectional approach. The sampling technique used was purposive sampling with a sample of 127 respondents diagnosed with hypertension. Results: Dominant fa

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Usman, Umar, Bello Magaji Arkilla, Abduljalil Alfa Ismail, and Usman Dauda. "TIME-TO-OPTIMAL CONTROL OF HYPERTENSION USING KAPLAN-MEIER ESTIMATOR, COX PROPORTIONAL HAZARD AND WEIBULL MODEL." FUDMA JOURNAL OF SCIENCES 6, no. 5 (2022): 71–75. http://dx.doi.org/10.33003/fjs-2022-0605-1096.

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Hypertension is a worldwide public health challenge. The study investigated the time it takes to attain an optimal control of hypertension and the major factors that influence the control in Specialist Hospital, Sokoto. A retrospective cohort study was conducted involving 300 patient records. The population consisted all hypertensive patients on follow-ups at Specialist Hospital Sokoto from1st February, 2015 to 1st February, 2021.Statistical Package for the Social Sciences version 20 and R software were used for descriptive, Kaplan-Meier estimator, Cox Proportional Regression (CPH) Model

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Radhika, A. R. "Drug utilization study of antihypertensive drugs in a tertiary care hospital." International Journal of Basic & Clinical Pharmacology 7, no. 12 (2018): 2309. http://dx.doi.org/10.18203/2319-2003.ijbcp20184680.

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Background: Hypertension is a major common disease and effects a million of people worldwide. And is risk factor for other diseases like cardiovascular diseases, stroke etc. The aim of our study was undertaken to study the utilization pattern of anti hypertensive drugs at a tertiary care hospital. The guidelines for the treatment of hypertension are put forward by the Joint National Committee (JNC) on detection, evaluation and treatment of blood pressure. The Indian guidelines endorsed by the cardiology society of India, the hypertension society of India, and Indian college of physicians close

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Raut, Binod, and Anjan Khadka. "Patterns of use of drugs in hypertension in geriatric patients in the department of medicine at tertiary care hospital of Nepal." Birat Journal of Health Sciences 5, no. 3 (2020): 1155–60. http://dx.doi.org/10.3126/bjhs.v5i3.33685.

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Introduction: In Nepal, the prevalence of hypertensive in elderly population is 41.7% aged 65 years or more. Hypertension increases with age leading to arterial stiffness and endothelial dysfunction. The prevalence of hypertension is 20% of urban populations. Blood pressure control with the use of antihypertensive drugs reduces cardiovascular complications in geriatric patients. Objectives: The objective of our study is to know the various patterns of drugs used in geriatrics hypertensive patient along with their co-morbidities and to know the most commonly used antihypertensive drug in

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Ma, Zhiyi, Yuqing Zhang, and Yang Xu. "ANALYSIS OF DETECTION RATE OF EARLY EVENING ELEVATED BLOOD PRESSURE IN HYPERTENSIVE PATIENTS BY AMBULATORY BLOOD PRESSURE MONITORING." Journal of Hypertension 42, Suppl 1 (2024): e194. http://dx.doi.org/10.1097/01.hjh.0001021388.64951.d1.

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Objective: The aim of the study is to investigate the detection rate of early evening elevated blood pressure (EEE) in treated and untreated hypertensive patients by ambulatory blood pressure monitoring. Design and method: From February 1, 2020 to February 28, 2023, the total of 1413 hypertensive patients underwent ambulatory blood pressure monitoring in 13 medical institutions through the National 13th Five Year Plan Major Cooperation Group for Chronic Disease Prevention and Control (Research on the Application of Lifestyle and Nutritional Intervention Techniques and Strategies for Obesity an

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Murty, MSN, Rajesh Pandey, Sibeka Behera, J. Jayakrishnan, Vivek Hande, and Vineet Behera. "Plasma Renin-guided Therapy in Patients of Primary Hypertension on Antihypertensives: A Prospective Cohort Study." Journal of the Association of Physicians of India 70, no. 8 (2022): 31–36. http://dx.doi.org/10.5005/japi-11001-0061.

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Background: Most guidelines for hypertension overlook the underlying pathophysiologic basis in deciding antihypertensives. Based on renin levels, hypertension may be classified as high-renin hypertension (HRH), low-renin hypertension (LRH), and normal-renin hypertension (NRH). The study examined the renin levels in a hypertensive population and assessed the effect of renin-guided antihypertensive management on blood pressure (BP) control. Materials and methods: This study was a single-center prospective cohort study. Subjects with primary hypertension (aged 20–60 years) on antihypertensives we

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Dr.Syed, Jalal Ud Din Dr.Tafseer Zahra Dr.Iqra Fatima. "AN OBSERVATIONAL STUDY OF PRESCRIBING PATTERN OF DRUGS USED IN THE TREATMENT OF HYPERTENSION IN A TERTIARY CARE TEACHING HOSPITAL." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 03 (2019): 5247–53. https://doi.org/10.5281/zenodo.2592538.

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<strong><em>Background: </em></strong><em>Hypertension has been the most common diseases that are chronic in nature and lead to high morbidity. To improve the patient survival, the early and efficient management of essential hypertension is needed, also to prevent complications and the established anti-hypertensives have paramount importance. Objective of the study is to prescribe anti-hypertensive drugs and know about patterns in Jinnah Hospital lahore .<strong>Methods: </strong>A cross-sectional observational study was undertaken and 205 patients suffering from primary hypertension were hand

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Dr.Samra, Asif Dr.Mehvish Altaf Dr.Tayyaba Asma. "STUDY TO KNOW PRESCRIBING PATTERN OF DRUGS USED FOR CONTROL OF HYPERTENSION IN A TERTIARY CARE TEACHING HOSPITAL IN PAKISTAN." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 03 (2019): 6365–71. https://doi.org/10.5281/zenodo.2604302.

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<strong><em>Background: </em></strong><em>Hypertension has been the most common diseases that are chronic in nature and lead to high morbidity. To improve the patient survival, the early and efficient management of essential hypertension is needed, also to prevent complications and the established anti-hypertensives have paramount importance. Objective of the study is to prescribe anti-hypertensive drugs and know about patterns in a tertiay care hospital of lahore<strong>Methods: </strong>A cross-sectional observational study was undertaken and 205 patients suffering from primary<strong> </str

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Athica Puteri Basyari, Selvina Alisandra Fahrial, and Tantiana, drg., M. Kes. "Evaluation of salivary flow rate and composition in hypertensive patients taking antihypertensive drugs consuming." World Journal of Advanced Research and Reviews 25, no. 1 (2025): 309–13. https://doi.org/10.30574/wjarr.2025.25.1.0005.

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Background: Hypertension patients are recorded by WHO to increase continuously along with the increase in population, accounting for 29% of the world's citizens suffering from hypertension. Most people with hypertension take hypertension drugs. The use of antihypertensive drugs varies and can cause several side effects on the oral cavity, especially the salivary flow rate. The purpose of this study was to evaluate the flow rate and composition of saliva in hypertensive patients who take hypertension drugs. This study uses a systematic review method by searching for articles related to evaluati

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Kušljugić, Zumreta, Katarina Divković, Fahir Baraković, et al. "Effects of nebivolol on artery hypertension--multicentre study Bosnia and Herzegovina." Bosnian Journal of Basic Medical Sciences 5, no. 1 (2005): 42–51. http://dx.doi.org/10.17305/bjbms.2005.3334.

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Hypertension is a major risk factor for cardiovascular diseases; drugs that reduce blood pressure and simultaneously improve or reverse endothelian dysfunction, as nebivolol, may be advantageous in terms of cardiovascular protection. The objective of this study is to show the anti-hypertensive efficacy and safety of nebivolol (5 mg once a day) given to patients with arterial hypertension for 3 months. It should also provide information about drug's influence on laboratory tests--fasting blood glucose and serum cholesterol, triglyceride and creatinine concentrations. Six centers--Tuzla, Sarajev

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Tanase, Daniela Maria, Evelina Maria Gosav, Smaranda Radu, et al. "Arterial Hypertension and Interleukins: Potential Therapeutic Target or Future Diagnostic Marker?" International Journal of Hypertension 2019 (May 2, 2019): 1–17. http://dx.doi.org/10.1155/2019/3159283.

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Hypertension as a multifactorial pathology is one of the most important cardiovascular risk factors, affecting up to 30-40% of the general population. Complex immune responses are involved in the inflammatory mechanism of hypertension, with evidence pointing to increased inflammatory mediators even in prehypertensive patients. Increased vascular permeability, thrombogenesis, and fibrosis, effects that are associated with sustained hypertension, could be attributed to chronic inflammation. Chronic inflammation triggers endothelial dysfunction via increased production of ROS through proinflammat

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Sumino, H., M. Nara, K. Seki, et al. "Effect of Antihypertensive Therapy on Blood Rheology in Patients with Essential Hypertension." Journal of International Medical Research 33, no. 2 (2005): 170–77. http://dx.doi.org/10.1177/147323000503300204.

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Hypertension is an important risk factor for cardiovascular disease, and antihypertensive drugs can decrease the occurrence of such events in hypertensive patients. This study compared the rheological properties of blood in 22 untreated hypertensive patients, 42 patients taking antihypertensive drugs and 74 normotensive subjects. Using a microchannel method, the whole blood passage time was measured and blood movement was observed with a microscope connected to an image display unit. The blood passage time in untreated hypertensive patients was significantly higher than in treated hypertensive

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Islam, T., MN Huda, S. Hossain, et al. "Study on Stroke among Hypertensive Patients in a Teaching Hospital." TAJ: Journal of Teachers Association 27, no. 2 (2018): 30–32. http://dx.doi.org/10.3329/taj.v27i2.37636.

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Stroke is one of the commonest causes of death and disability in the world. Hypertension is the greatest treatable risk factor for both ischernic and hemorrhagic stroke. This study was carried out in Rajshahi Medical College Hospital to observe the incidence of stroke among hypertensive patients and to compare the occurrence of stroke among patients who were taking anti-hypertensive drugs regularly and those who were taking irregularly. Hundred stroke patients with hypertension were selected randomly. Ischemic stroke 66% and hemorrhagic stroke 34% was observed. Majority (64%) of hypertensive p

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Faris, Nabil Fatani Royof Mohammed AlSobaei Nora Saad Alobodi Zana Homoud Alshehri Hessah Abdulrahman Alrajih Albandari Abdulrahman Fallatah. "POOR COMPLIANCE TO ANTI-HYPERTENSIVE DRUGS AMONG PATIENTS IN SAUDI ARABIA." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 02 (2019): 3752–58. https://doi.org/10.5281/zenodo.2563232.

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<strong><em>Background:</em></strong><em> Poorly controlled hypertension may lead to several serious health problems, including stroke, aneurysms, coronary artery disease, kidney disease and peripheral artery disease.</em> <strong><em>Objectives:</em></strong><em> This study aimed at exploring the magnitude of the problem of non-compliance with antihypertensive drugs among patients in Saudi Arabia and identifying the associated factors. </em> <strong><em>Subjects and Methods:</em></strong><em> a cross-sectional study was carried out during the period January to August 2018 through social media

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Silva, Ricardo Pereira, Pedro Felipe de Sousa Pinheiro, Haniel Douglas Brito, et al. "Clinical features of resistant and refractories hypertensives submitted to 24-hour ABPM." Brazilian Journal of Health Review 7, no. 3 (2024): e69523. http://dx.doi.org/10.34119/bjhrv7n3-052.

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Ten to twenty percent of patients with hypertension are considered resistant to treatment. Resistant hypertension is one in which the patient cannot be controlled with the use of three drugs at maximum doses, including a diuretic, or when blood pressure (BP) is controlled with the use of four or more anti-hypertensive drugs. Refractory hypertension is an extreme phenotype of resistant hypertension, when the BP cannot be controlled despite the usage of four anti-hypertensives,. PURPOSE- evaluate the clinical profile of resistant and refractory hypertensives by ABPM. METHODS- From January of 201

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Harun, Harnavi. "Tingkat Kepatuhan Minum Obat Pasien Hipertensi Dinilai dengan Morisky Medication Adherence Scale - 8 (MMAS-8) di RSUP M Djamil Padang." Seminar Nasional ADPI Mengabdi Untuk Negeri 1, no. 1 (2020): 137–41. http://dx.doi.org/10.47841/adpi.v1i1.40.

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Introduction : Hypertension is a disease that is commonly found and one of the causes of death allover the world. Riset Kesehatan Dasar in 2013 shows that the prevalence of hypertension in Indonesiais 26.5%. The lack of medication adherence of hypertensive patients is a major cause of hypertensiontherapy failure. Non-adherence to antihypertensive drugs is a potential factor that can cause variouscomplications such as heart failure, stroke, kidney failure and blindness. The purpose of this study wasto determine the level of medication adherence for hypertensive patients in M. Djamil HospitalPad

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K. Deepak Maharshi, T. Vani, M. Navaneetha, G. Jyothi, Shantveer Halcher, and Gururaj V Wadageri. "Prescription pattern of anti-hypertensive drugs among hypertensive patients at district hospital." International Journal of Research in Hospital and Clinical Pharmacy 1, no. 2 (2019): 57–61. http://dx.doi.org/10.33974/ijrhcp.v1i2.86.

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Background: To conduct a prospective observational study on prescribing pattern of anti-hypertensive drug in the department of general medicine in Government District hospital, Gulbarga. In this study it was aimed to evaluate the current practice of anti-hypertensive drug by comparing with JNC-8 guidelines in population. Objectives: The objective of our study is to determine the prescription pattern of antihypertensive drugs and adherence to JNC8 guidelines and to find out the most prescribed anti-hypertensive drugs. Methods: A Prospective Observational Study of 06 months was conducted. Undert

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Lahamate, Shrikant B., Syed U. Razvi, Mirza S. Baig, and Sudhakar M. Doifode. "Drug utilization study of antihypertensive drugs used in the treatment of second and third trimester of pregnancy in tertiary care hospital." International Journal of Basic & Clinical Pharmacology 7, no. 9 (2018): 1733. http://dx.doi.org/10.18203/2319-2003.ijbcp20183480.

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Background: Hypertensive disorders are major cause of the perinatal and maternal mortality and morbidity worldwide. Aim of study was to evaluate current trend of antihypertensive drugs and to assess frequency and distribution of antihypertensive drugs in pregnancy.Methods: A retrospective observational study was conducted in a tertiary care hospital for period of six months in collaboration with department of obstetrics and gynaecology. Patients data recorded in case report form and analysed to study prescription pattern and related information.Results: Total of 104 cases were enrolled in this

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., Shalini, and Manish Kumar Goel. "Non-Adherence to Anti-Hypertensive Treatment." Indian Journal of Community Health 32, no. 1 (2020): 126–29. http://dx.doi.org/10.47203/ijch.2020.v32i01.025.

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Background: In developed countries, adherence among patients suffering from chronic diseases averages only 50%; in developing countries it is assumed to be much lower. Aims & objectives: To find out the prevalence of non-adherence to antihypertensive treatment among individuals seeking anti-hypertensive treatment from tertiary care hospital in New Delhi & to find out the factors related to non-adherence to the anti-hypertensive treatment among study subjects. Material and Methods: A cross-sectional hospital-based study was conducted from June to October 2018 among 150 diagnosed cases o

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Sharma, Vishal, Beena Sharma, Rajveer Singh Rathore, and Lokendra Sharma. "A prospective observational study of prescription pattern of antihypertensive drugs in general medicine outpatient department of associated hospital RUHS CMS, Jaipur." International Journal of Basic & Clinical Pharmacology 12, no. 5 (2023): 682–87. http://dx.doi.org/10.18203/2319-2003.ijbcp20232564.

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Background: The increasing prevalence of hypertension is attributed to population growth, ageing and behavioural risk factors, such as unhealthy diet, harmful use of alcohol, lack of physical activity, excess weight and exposure to persistent stress. The aim of study is the prescribing pattern and the consumption of antihypertensive drugs in isolated hypertensive patients and in hypertensive patients with different co-existing morbidities. Methods: The present study is a Prospective observational study. The study was conducted at Medicine Department of associated hospital of RUHS College of Me

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Dr., Karande Monika Bhosale* Dr. V. Y. Lokhande. "Microneedle For the Transdermal Delivery of Hypertensive Drugs." International Journal of Pharmaceutical Sciences 3, no. 4 (2025): 1732–58. https://doi.org/10.5281/zenodo.15211904.

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Among the many benefits of the MNs-based system are its low cost, excellent medical efficacy, relative safety, and painless drug application. An overview of studies conducted in MNs on the transdermal delivery of medications for hypertension is given in this review article. The pharmacokinetics, manufacturing techniques, and drug release mechanism, applications in medicine, a future difficulties are some of the crucial characteristics of micro needles that are covered. This targeted review opens the door for future pharmaceutical applications by giving a summary of published research and the l

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Suvidha s. Mane, Suvidha s. Mane, laxmikant m. Purane, and vivekkumar k. Redasani. ""A Comprehensive Review on Animal Models for Screening of Antihypertensive Drugs"." International Journal of Pharmaceutical Research and Applications 10, no. 2 (2025): 472–83. https://doi.org/10.35629/4494-1002472483.

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Hypertension is a major cause of death and disability, with cardiovascular disease and hypertension being the leading causes in wealthy nations. Animal models have been used to study its pathophysiology, aetiology, consequences, treatment, and antihypertensive medication evaluation. Genetically hypertensive rats are commonly used in therapeutic investigations. A summary of the traits and importance of both conventional and genetic animal models of hypertension is included as: In-Vitro Animal Models: Antagonism of Endothelin Receptors in Porcine Isolated Hearts and Monocrotaline induced pulmona

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Dr., Jazba Mussaddiq Dr. Saleem Ullah Dr. Muhammad Mujahid. "FREQUENCY OF RESISTANT HYPERTENSION IN HYPERTENSIVE PATIENTS PRESENTING TO NISHTAR HOSPITAL, MULTAN, PAKISTAN." Indo American Journal of Pharmaceutical Sciences 05, no. 05 (2018): 3920–23. https://doi.org/10.5281/zenodo.1248888.

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<strong><em>Objective:</em></strong><em> Evaluation of resistant hypertension amongst hypertensive patients presenting to Nishtar hospital, Multan, Pakistan. <strong>Methodology:</strong> A cross sectional on 150 hypertensive patients was conducted in department of internal medicine, Nishtar hospital Multan during January to June 2017. Resistant hypertension was defined as failure of response to at least 3 anti-hypertensive drugs prescribed at the optimal dosage. All these drugs belong to different groups, diuretics being a part of prescribed regimen. Patients’ blood pressure remains 140

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