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Dissertations / Theses on the topic 'Hypertensive response'

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Published: 3 June 2025

Last updated: 31 July 2025

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1

Davis, Jacqueline A. "The hypertensive response to repeated days of heat-exercise exposure." Virtual Press, 1989. http://liblink.bsu.edu/uhtbin/catkey/562777.

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The physiological responses of hypertensive subjects to a single bout of exercise in a hot environment have been investigated. It was the purpose of this study to compare the effect of successive days of exercise in the heat on borderline hypertensive and normotensive individuals, with particular interest being paid to the positive relationship that exists between plasma volume and blood pressure. Eight hypertensive subjects (HT) and 8 normotensive controls (NT) performed a standardized work task, (walking for 60 minutes at 3.5 mph on a 5% grade), in dry heat, (40C, 257. RH), on 7 successive d

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2

Wilson, Richard. "Total peripheral resistance response to metaboreflex stimulation in hypertensive adults." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 67 p, 2009. http://proquest.umi.com/pqdweb?did=1889099131&sid=4&Fmt=2&clientId=8331&RQT=309&VName=PQD.

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3

Modgil, Amit. "Angiotensin (1-7) Attenuates the Chronotropic Response to Angiotensin II via Stimulation of PTEN in Spontaneously Hypertensive Rat Brain." Diss., North Dakota State University, 2013. https://hdl.handle.net/10365/26797.

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The pathogenesis of hypertension and its mode of progression are complex, multifactorial and incompletely understood. Several studies have focused on the beneficial effects of peripheral Ang (1-7) in the regulation of cardiovascular functions, showing the counter-regulatory effects of Ang (1-7) against the actions of Ang II in the periphery. However, its actions in the central nervous system are not completely understood. In the present study, our main goal was to determine the central action of Ang (1-7) and its interaction with Ang II in the blood pressure control. Previous studies reported

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4

Inglis, Stuart Donald. "Morphological Characteristics of Hind Limb Musculature in Normotensive and Hypertensive Hamsters in Response to Unloading, Overloading, and Endurance Training." Ohio University / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1173190139.

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5

Heuck, Emily. "Macronutrient intake and BMI change as potential mediators of CVD risk factor response among hypertensive adolescents on a DASH dietary intervention." University of Cincinnati / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1522312168801163.

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6

Forino, Andrew Stephen. "Determining Effects of the PAF-R and Anti-Hypertensive Drugs Mediated Microvesicle Particle Release in Modulating Anti-Tumor Response of Lung Cancer." Wright State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=wright1590691151424173.

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7

McCarthy, Joseph C. "Effects of Relaxin on Cardiac Performance and Coronary Artery Reactivity in Aged Spontaneously Hypertensive Female Rats." University of Akron / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=akron1401189544.

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8

Gadkari, Tushar V. "Effect of Arginine and Oscillatory Ca2+ on Vascular Response Mediated Via Nitric Oxide Signaling in Normal and Salt Sensitive Hypertensive Rat Mesenteric Arterioles." FIU Digital Commons, 2013. http://digitalcommons.fiu.edu/etd/891.

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Hypertension, a major risk factor in the cardiovascular system, is characterized by an increase in the arterial blood pressure. High dietary sodium is linked to multiple cardiovascular disorders including hypertension. Salt sensitivity, a measure of how the blood pressure responds to salt intake is observed in more than 50% of the hypertension cases. Nitric Oxide (NO), as an endogenous vasodilator serves many important biological roles in the cardiovascular physiology including blood pressure regulation. The physiological concentrations for NO bioactivity are reported to be in 0-500 nM range.

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9

Yu, Zhen. "Altered drug responses in diabetic and hypertensive-diabetic cardiomyopathy." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/29406.

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Diabetes mellitus has been associated with both clinical and experimental cardiac dysfunction. Diabetic cardiomyopathy which is characterized by depressed cardiac contractility is accompanied by a variety of biochemical changes in Ca⁺⁺ metabolism. This cardiomyopathy may occur in the presence of normal coronary arteries and normal blood pressure. However, some studies have shown that hypertension is more prevalent among diabetics and can aggravate the cardiovascular abnormalities associated with diabetes. To understand the mechanisms of diabetic cardiomyopathy and consequences of combined hype

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10

Johnson, Darren A. "Cardiovascular responses to physical stressors in normotensive and exercise hypertensive individuals." Thesis, University of Ottawa (Canada), 1995. http://hdl.handle.net/10393/10100.

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This study compared the cardiovascular responses to the PWC 140, cold pressor test (CPT), and isometric hand grip (IHG), to evaluate the consistency in the blood pressure response among these physical stressors. Eighteen resting normotensive males were classified as either normotensive at exercise or exercise hypertensive on the basis of their blood pressure response to the first stage of the Canadian Aerobic Fitness Test (CAFT) for their age group. Subjects were administered a 6-min PWC 140 bicycle ergometer test, a 120 sec CPT (forearm and hand immersion), and a 120 sec IHG at 30% MVC. Systo

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11

Hintsala, H. (Heidi). "Cardiovascular responses to cold exposure in untreated hypertension." Doctoral thesis, Oulun yliopisto, 2018. http://urn.fi/urn:isbn:9789526219783.

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Abstract Cold weather associates with higher cardiovascular morbidity and mortality in various climates. It is also known that exposure to a cold environment instantly activates sympathetic nervous system and elevates blood pressure (BP) in healthy individuals. Hypertension can increase sympathetic reactivity and arterial stiffness, and could therefore exaggerate these cold-related changes. We implemented an experimental study to assess cardiovascular responses to habitual type of cold exposure among subjects with untreated hypertension. We selected a random sample of middle-aged men in the ci

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12

Morgan, Myfanwy Ann. "Beliefs and responses to hypertension : patients' and practitioners' perspectives." Thesis, King's College London (University of London), 1993. https://kclpure.kcl.ac.uk/portal/en/theses/beliefs-and-responses-to-hypertension--patients-and-practitioners-perspectives(d94794b9-3225-43ba-8c8c-d9f20e444726).html.

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13

Olney, Christine M. "Back massage : long term effects and dosage determination for persons with pre-hypertension and hypertension." [Tampa, Fla] : University of South Florida, 2007. http://purl.fcla.edu/usf/dc/et/SFE0001923.

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14

Burchell, Amy. "Renal denervation for resistant hypertension : predictors of procedural response and efficacy." Thesis, University of Bristol, 2019. http://hdl.handle.net/1983/a5ba7e8a-f628-4691-adaa-2104f2a733da.

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Background: Renal denervation (RDN) is an endovascular ablation technique for the treatment of resistant hypertension through disruption of the afferent and efferent renal nerves, thereby abolishing the feedback loop which drives increased sympathetic nerve activity and hypertension. This study aimed to develop measures of technical efficacy for RDN and to identify parameters to guide patient selection for this invasive therapy. Methods: Autonomic profiling, including measurement of office and ambulatory BP, muscle sympathetic nerve activity (MSNA), heart rate variability, sympathovascular tra

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15

Uys, Aletta Sophia. "Comparing autonomic and cardiovascular responses in African and Caucasian men : the SABPA study / Aletta Sophia Uys." Thesis, North-West University, 2012. http://hdl.handle.net/10394/9851.

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Motivation Hypertension is a pertinent health problem for urban black African men (hereafter referred to as African). Sympathetic hyperactivity and a dominant α-adrenergic response pattern have both been implicated as contributing factors to their poor cardiovascular health. In addition to the deleterious effect of neurogenic hypertension on target organs, sympathetic hyperactivity may promote the accelerated progression of left ventricular hypertrophy and structural vascular disease. Aim The overarching aim of this study is to scrutinize autonomic control of the cardiovascular system in a coh

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16

Phatcharanuruk, Thapin. "Thai people's responses to high blood pressure : beliefs and constraints." Thesis, University of Nottingham, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367997.

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17

Clift, Paul F. J. "Endothelin and the cardiovascular response to hypoxia." Thesis, Imperial College London, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.341139.

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18

Kelsey, Kira Q. "Familial history of hypertension : hemodynamic responses to exercise in children." Virtual Press, 1996. http://liblink.bsu.edu/uhtbin/catkey/1020150.

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Hypertension afflicts one in four American adults and is a major risk factor for cardiovascular disease. Studies have shown that a family history of hypertension is an important predictor of future hypertension. Two hemodynamic factors control blood pressure (BP); cardiac output (CO) and total peripheral resistance (TPR). Although children of hypertensive parents may exhibit normal levels of these hemodynamic variables at rest, the response of these variables during exercise stress may differ. Therefore, the present study was designed to investigate whether children with a positive family hist

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19

Lindsay, Gregory W. "Enhanced Renal Sympathetic and Cardiovascular Responses to Substance P in Hypertension." Digital Commons @ East Tennessee State University, 1993. https://dc.etsu.edu/etd/2718.

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Blood pressure, heart rate, and renal sympathetic nerve responses were measured in 9-13 week old male spontaneously hypertensive rats (SHR) and compared to those in age and sex-matched Wistar-Kyoto (WKY) rats following intravenous injection of the neuropeptide substance P (SP), the nicotinic stimulant 1,1-dimethyl-4-phenylpiperazinium (DMPP), and the adrenoceptor stimulant norepinephrine (NE). Charles River Sprague-Dawley (CD) rats were used in some studies to develop methodologies. Measurements were made in control rats and also following sinoaortic denervation, pithing, ganglion blockade, or

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20

Tsai, Pei-Shan. "Hemodynamics and arterial properties underlying pressure responses to cognitive stress in borderline hypertensives." [Gainesville, Fla.] : University of Florida, 2001. http://purl.fcla.edu/fcla/etd/anp4007.

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Thesis (Ph. D.)--University of Florida, 2001.<br>Title from first page of PDF file. Document formatted into pages; contains xi, 132 p.; also contains graphics. Vita. Includes bibliographical references (p. 120-130).

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21

Franke, Warren D. "Effects of [alpha]₁-receptor blockade on the hemodynamic responses to exercise in young normotensives and hypertensives /." This resource online, 1991. http://scholar.lib.vt.edu/theses/available/etd-07282008-135332/.

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22

Lawton, Bethan. "Microvascular Responses to Propofol Anaesthesia in an In Vivo Model of Hypertension." Thesis, University of Sheffield, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.521862.

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23

Weinberg, Julius Rolf. "A study of the circulatory responses to fever with and without hypertension." Thesis, University of Oxford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.258154.

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24

Osuafor, Godswill Nwabuisi. "Aspects of the interrelation between hypertension and insulin resistance." Thesis, University of the Western Cape, 2009. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_6176_1298445712.

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<p>Conclusion of this study: These data suggest that 6 weeks of high-fat feeding induces hypertension but does not produce obesity, dyslipidemia and insulin resistance. However, this model may be useful in studying vascular reactivity in hypertension in the absence of insulin resistance.</p>

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25

Tomimura, Suely. "Avaliação do estresse oxidativo e modulação autonômica cardiovascular pós-irradiação de laser de baixa intensidade em ratos espontaneamente hipertensos: estudo experimental." Universidade Nove de Julho, 2013. https://bibliotecatede.uninove.br/handle/tede/1132.

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Submitted by Nadir Basilio (nadirsb@uninove.br) on 2015-07-20T18:01:54Z No. of bitstreams: 1 Suely Tomimura.pdf: 1781054 bytes, checksum: acaac7dbd088721fbe65530e5cd96c5f (MD5)<br>Made available in DSpace on 2015-07-20T18:01:54Z (GMT). No. of bitstreams: 1 Suely Tomimura.pdf: 1781054 bytes, checksum: acaac7dbd088721fbe65530e5cd96c5f (MD5) Previous issue date: 2013-12-17<br>Due to the increasing numbers of Systemic Arterial Hypertension (HBP) patients in population and its senescence, steadily increased from 600 million in 1980 to 1.2 billion in 2008. The World Health Organization (WHO) i

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26

Campbell, Ian William. "Insulin resistance, hypertension and the insulin-responsive glucose transporter, GLUT-4." Thesis, University of Glasgow, 1997. http://theses.gla.ac.uk/8472/.

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Insulin resistance is a disease state characterised by the reduced ability of insulin to exert its effects in peripheral tissues, skeletal muscle and adipose tissue. This condition has been associated with a number of other disease states including obesity and hypertension. The hypertensive Milan rat has previously been shown to be insulin resistant. Unlike any other hypertensive, insulin resistant model, the Milan rat has a normotensive, isogenic control which responds normally to insulin. As GLUT-4, the insulin-stimulated glucose transporter, had been implicated in insulin resistance I exami

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27

Morris, Ray William. "Changes in CW-Doppler aortic blood flow responses with passive tilting in normo- and borderline hypertensive men." Thesis, Virginia Tech, 1989. http://hdl.handle.net/10919/44126.

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Continuous-wave (CW) Doppler echocardiographic responses to passive tilting were measured in 39 men using the following protocol: standing; supine; +20Â° head-up; supine; â 20Â° head-down. Twenty of the subjects were normotensive (NTN) and the rest were borderline hypertensive (B-HTN) according to prior medical diagnosis. Doppler recordings of blood flow for aortic peak velocity (Pkv), peak acceleration (PkA), and stroke velocity integral (SVI) were taken after 15 minutes in each posture. A skilled technician, using the measurement procedures recommended by the instrument manufacturer, positi

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28

Craft, Laura Lee III. "Effects of the Angiotensin II Antagonist, Losartan, on Circulo-Respiratory Responses to Submaximal Exercise in Hypertensive Women." Diss., Virginia Tech, 1997. http://hdl.handle.net/10919/29261.

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The effects of the antihypertensive agent Losartan (Lo), on acute exercise performance was assessed in six sedentary, hypertensive women. The purpose, benefits and potential risks of the study were explained to each subject and their informed consent received. In a double blinded crossover design subjects were randomized to 7 days of (Lo) 50 mg, once every morning or placebo (Pl). Subjects reported to the laboratory for an exercise trial on the 7th treatment day. They received the final treatment dose 2.5 hours before the exercise trial. Blood samples for analysis of plasma renin activi

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29

Fowler, Robin. "The impact of elevated pulmonary artery pressure on exercise responses." Thesis, Curtin University, 2012. http://hdl.handle.net/20.500.11937/2637.

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Background and research questions. The four studies reported in this thesis investigated the implications of an elevated pulmonary artery pressure (PAP) on the response to an exertional challenge. The level of symptoms and exertion that healthcare professionals consider appropriate for patients with pulmonary arterial hypertension (PAH) was explored in the first study. In studies two, three, and four, exercise responses and exercise testing were evaluated in individuals with an elevated PAP on exercise, but a normal PAP at rest (exercise-induced pulmonary arterial hypertension, [EIPAH]).The fo

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30

Gantt, MeLisa. "The Effect of Combat Exercises on Cardiovascular Response: An Exploratory Study." Doctoral diss., University of Central Florida, 2010. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/2232.

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PURPOSE: Hypertension (HTN) affects one in every three adults in the United States. Often associated with the older population, this silent killer has emerged in an unsuspecting group, young military soldiers. With the rapid succession of multiple deployments, long intervals between blood pressure (BP) assessments, and the absence of cardiovascular (CV) measures during the pre and post deployment health screenings; soldiers may be at higher risk for HTN than their civilian counterparts of the same age. The purpose of this study was to explore real-time continuous CV measures of soldiers before

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31

Pietras, Kristian. "Inhibition of PDGF receptor signaling in tumor stroma : Effects on interstitial hypertension, drug uptake and therapeutic response." Doctoral thesis, Uppsala University, Ludwig Institute for Cancer Research, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2633.

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<p>The role of platelet-derived growth factor (PDGF) in malignancies involves both autocrine and paracrine stimulation of cells within the tumor. The interstitial fluid pressure (IFP) is one of the forces that govern the transvascular flow of fluids. In both experimental and clinical cancers, the IFP is elevated and is thought to act as a barrier for delivery of drugs. Increasing evidence points to PDGF as a positive regulator of the interstitial fluid pressure in loose connective tissue. In this thesis, the effect of PDGF receptor inhibition on the tumor IFP, transvascular transport and effic

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32

Taha, Mohamad. "Investigating the Role of Sirtuin 1 in the Pulmonary Vascular Response to Chronic Hypoxia-Induced Pulmonary Hypertension." Thesis, Université d'Ottawa / University of Ottawa, 2018. http://hdl.handle.net/10393/37550.

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Background: Pulmonary arterial hypertension (PAH) is a devastating disease characterized by increased pulmonary artery pressure, leading to right ventricle hypertrophy and ultimately heart failure and death. Sirtuin 1 (SIRT1) is an NAD+ dependent protein deacetylase that has been strongly implicated as a crucial link between longevity, stress response and maintenance of vascular health. In this thesis, we investigated the role of SIRT1 in the pulmonary vascular hypoxic response and the pathogenesis of pulmonary hypertension (PH) working under the hypothesis that SIRT1 plays a protective role i

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33

Morecroft, Ian. "5-HT-receptor mediated responses in pulmonary arteries : changes with developmental age and pulmonary hypertension." Thesis, University of Glasgow, 2000. http://theses.gla.ac.uk/6739/.

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34

Franke, Warren D. "Effects of Î±1-receptor blockade on the hemodynamic responses to exercise in young normotensives and hypertensives." Diss., Virginia Tech, 1991. http://hdl.handle.net/10919/38955.

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The purpose of this study was to determine if Î±1- adrenergic receptor blockade alters the hemodynamic response to exercise in young (<25 yr) male adult borderline hypertensives differently than in young normotensives. Five hypertensive (HTN, MAP>105 mmHg) and 7 normotensive (NTN, MAP<95 mmHg) college-age males underwent two 30 min bouts of cycle ergometry exercise at 50% V02Pk in a warm (25°C, 50% rh) environment; one bout occurred followed Î±1-receptor blockade with prazosin (HTN-Î±, NTN-Î±) and the other following placebo administration (HTN-p, NTN-p). At rest, HTN-p exhibited an elevated c

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35

Gerzenstein, Sabrina Melisa. "Pharmacogenomics of the Intraocular Pressure Response to Glucocorticoids." Scholarly Repository, 2009. http://scholarlyrepository.miami.edu/oa_theses/285.

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Glucocorticoids (GCs) have been widely used as a therapeutic agent for diverse inflammatory ocular diseases. However, a high percentage of patients undergoing this treatment develop high intraocular pressure (IOP), which if left unsupervised may lead to glaucoma. It is believed that the IOP elevation in response to GC treatment has a genetic determinant. In order to test this hypothesis, we analyzed in 52 patients the presence of single nucleotide polymorphisms (SNPs) in the glucocorticoid receptor gene (GR), the principal mediator of GCs uptake by the cells. We studied six GR SNPs previously

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36

Kenyon, Kyle Adrian. "First Order System Response of the Pulmonary Vasculature in Pulmonary Hypertension| Resistance-Compliance Constant Changes with Vascular Reactivity." Thesis, University of Colorado at Denver, 2017. http://pqdtopen.proquest.com/#viewpdf?dispub=10276553.

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<p> The only clinical diagnostic and prognostic biomarker for measuring afterload on the right ventricle caused by Pulmonary Arterial Hypertension is Pulmonary Vascular Resistance (PVR). However, recent studies have shown that Pulmonary Vascular Compliance (PVC) is a better prognostic biomarker than PVR, and PVR and PVC are coupled. Thus, measuring and treating PVR will naturally restore PVC. However, there is current debate whether if coupling is occurring. To determine if coupling between PVR and PVC is taking place 324 patients underwent routine right heart catherization for hemodynamics da

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37

Wallenborn, Jacqueline Grace Kodavanti Urmila. "Cardiopulmonary responses of Wistar Kyoto (WKY), spontaneously hypertensive rats (SHR) and stroke prone SHR (SHRSP) to particulate matter (PM) exposure." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2006. http://dc.lib.unc.edu/u?/etd,724.

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Thesis (M.S.)--University of North Carolina at Chapel Hill, 2006.<br>Title from electronic title page (viewed Oct. 10, 2007). "... in partial fulfillment of the requirements for the degree of Master of Science in the Department of Environmental Sciences and Engineering." Discipline: Environmental Sciences and Engineering; Department/School: Public Health.

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38

Viel, Émilie 1975. "Inflammatory responses in the vascular wall are up-regulated in hypertension and contribute to cardiovascular disease." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=115884.

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Hypertension is the number one cause of death worldwide. Low-grade inflammation has been identified as one of the mechanisms contributing to blood pressure elevation and remodeling of the vasculature in hypertension. Mechanisms involved in vascular inflammation and hypertension remain elusive. Vasoactive peptides such as endothelin-1 (ET-1) and angiotensin II (Ang II), oxidative stress and infiltration of immune cells are increased in cardiovascular tissues of hypertensive individuals. Since the vasculature is a major regulator of blood pressure levels, the hypothesis has been proposed that va

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39

Docherty, Cheryl Catherine. "Endothelin-receptor mediated responses in pulmonary resistance arteries : effect of developmental age and left ventricular dysfunction." Thesis, University of Glasgow, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.241867.

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40

Lilly, Eamon C. "Change in Major Food Sources of Sodium in Response to a Dietary Intervention to Lower Blood Pressure in Adolescents." University of Cincinnati / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1553250336047347.

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41

Liu, Donald. "Ultraviolet A irradiation on human skin : nitric oxide mediated cardiovascular responses." Thesis, University of Edinburgh, 2012. http://hdl.handle.net/1842/8179.

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Cardiovascular disease (CVD) such as hypertension and stroke are serious illnesses that impact on the lives of millions all over the world, with 972 million (26% of the world’s population) suffering from hypertension in year 2000, and an estimated 1.56 billion to be affected by 2025. Hypertension, being one of the most common CVD is associated with the development of stroke, peripheral vascular diseases, myocardial infarction, renal failure as well as cardiac failure. Several studies have shown a seasonal correlation for both the systolic and diastolic blood pressure in mankind. A hypertension

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Griffith, D. N. W. "The cerebral circulation in diabetes mellitus and hypertension and its responses to beta adrenergic receptor-blocking drugs." Thesis, University of Cambridge, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599714.

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43

Lewis, Allan. "Moderating effect of a single aerobic exercise session on the cardiovascular response to a stressful procedure 45 minutes later." Thesis, This resource online, 1994. http://scholar.lib.vt.edu/theses/available/etd-06112009-063046/.

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44

Leick, Katie. "A novel technique to study the time course of morphological and functional vascular responses to hypertension in conscious rats." Thesis, University of Iowa, 2010. https://ir.uiowa.edu/etd/696.

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Assessment of morphological vascular responses to exposure to cardiovascular risk factors in experimental animals requires ex vivo experiments that do not allow assessment of the time course of vascular alterations in individual subjects. We used a slit-lamp biomicroscope (resolution < 1 μm) to photograph the long posterior ciliary artery (LPCA) of the iris in conscious normotensive Wistar Kyoto rats (WKY, n=10) and spontaneously hypertensive rats (SHR, n=10) on normal-salt diet (NS) and in SHR (n=10) on high-salt diet (HS). The same segment along the LPCA was imaged in consecutive weekly imag

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45

Hamill, Claire. "In hypertension do smaller holes in arterial internal elastic lamina lead to fewer routes for myoendothelial junctions and hence less EDHF response?" Thesis, University of Glasgow, 2009. http://theses.gla.ac.uk/1398/.

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The work presented in this thesis describes the influence of the endothelium on smooth muscle cells, and how the structure of the internal elastic lamina (IEL) affects this relationship in mesenteric and saphenous arteries. This was enabled by the study of functional and confocal microscopy dye transfer experiments. Normotensive (WKY) and hypertensive (SHR) rats of 12 weeks and 6 months of age were used to assess the effect of hypertension and ageing on endothelial and smooth muscle cell communication. The endothelium-derived hyperpolarising factor (EDHF) response in mesenteric arteries was in

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46

Tiruneh, Missale. "Angiotensin II Type 1 Receptor Activation in the Subfornical Organ Mediates Sodium-induced Pressor Responses In Wistar Rats." Thèse, Université d'Ottawa / University of Ottawa, 2012. http://hdl.handle.net/10393/23119.

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Na+ sensitive hypertension in Dahl salt sensitive rats (Dahl S) or spontaneously hypertensive rats (SHR) is linked to intrinsic changes in the brain that favour increased Na+ entry into the cerebrospinal fluid (CSF) followed by increases in sympathetic hyperactivity and hypertension (Huang et al 2004). Similar responses are observed in salt resistant and Wistar rats that receive an intracerebroventricular (icv) infusion of Na+ rich artificial cerebrospinal fluid (aCSF) (Huang et al 2001, 2006). Downstream to increased CSF[Na+], a pathway has been described involving mineralocorticoid receptors

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47

Wagner, Allison. "Changes in knowledge, self efficacy and diet among adolescents with hypertension in response to a DASH diet Intervention utilizing the social cognitive theory." Cincinnati, Ohio : University of Cincinnati, 2005. http://www.ohiolink.edu/etd/view.cgi?acc%5Fnum=ucin1132255980.

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48

WAGNER, ALLISON M. "CHANGES IN KNOWLEDGE, SELF-EFFICACY AND DIET AMONG ADOLESCENTS WITH HYPERTENSION IN RESPONSE TO A DASH DIET INTERVENTION UTILIZING THE SOCIAL COGNITIVE THEORY." University of Cincinnati / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1132255980.

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49

Goins, Laura K. "The Effect of DASH Dietary Adherence and Participant Characteristics on CVD Risk Factor Response to a DASH Dietary Intervention in Adolescents with Elevated Blood Pressure." University of Cincinnati / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1504871786313111.

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WANSAPURA, ARSHANI N. "CHANGES IN FOOD SOURCES OF SODIUM IN THE DIETS OF ADOLESCENTS WITH HYPERTENSION IN RESPONSE TO A DIETARY INTERVENTION EMPHASIZING A DASH TYPE DIET." University of Cincinnati / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1154703684.

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