Relevant bibliographies by topics / Hyphal transition

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters

Academic literature on the topic 'Hyphal transition'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "Hyphal transition"

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Lindsay, Allia K., Aurélie Deveau, Amy E. Piispanen, and Deborah A. Hogan. "Farnesol and Cyclic AMP Signaling Effects on the Hypha-to-Yeast Transition in Candida albicans." Eukaryotic Cell 11, no. 10 (2012): 1219–25. http://dx.doi.org/10.1128/ec.00144-12.

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ABSTRACTCandida albicans, a fungal pathogen of humans, regulates its morphology in response to many environmental cues and this morphological plasticity contributes to virulence. Farnesol, an autoregulatory molecule produced byC. albicans, inhibits the induction of hyphal growth by inhibiting adenylate cyclase (Cyr1). The role of farnesol and Cyr1 in controlling the maintenance of hyphal growth has been less clear. Here, we demonstrate that preformed hyphae transition to growth as yeast in response to farnesol and that strains with increased cyclic AMP (cAMP) signaling exhibit more resistance
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Hazan, Idit, and Haoping Liu. "Hyphal Tip-Associated Localization of Cdc42 Is F-Actin Dependent in Candida albicans." Eukaryotic Cell 1, no. 6 (2002): 856–64. http://dx.doi.org/10.1128/ec.1.6.856-864.2002.

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ABSTRACT The rho-type GTPase Cdc42 is important for the establishment and maintenance of eukaryotic cell polarity. To examine whether Cdc42 is regulated during the yeast-to-hypha transition in Candida albicans, we constructed a green fluorescence protein (GFP)-Cdc42 fusion under the ACT1 promoter and observed its localization in live C. albicans cells. As in Saccharomyces cerevisiae, GFP-Cdc42 was observed around the entire periphery of the cell. In yeast-form cells of C. albicans, it clustered to the tips and sides of small buds as well as to the mother-daughter neck region of large-budded ce
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Carlisle, Patricia L., and David Kadosh. "A genome-wide transcriptional analysis of morphology determination inCandida albicans." Molecular Biology of the Cell 24, no. 3 (2013): 246–60. http://dx.doi.org/10.1091/mbc.e12-01-0065.

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Candida albicans, the most common cause of human fungal infections, undergoes a reversible morphological transition from yeast to pseudohyphal and hyphal filaments, which is required for virulence. For many years, the relationship among global gene expression patterns associated with determination of specific C. albicans morphologies has remained obscure. Using a strain that can be genetically manipulated to sequentially transition from yeast to pseudohyphae to hyphae in the absence of complex environmental cues and upstream signaling pathways, we demonstrate by whole-genome transcriptional pr
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Wang, Allen, Shelley Lane, Zhen Tian, Amir Sharon, Idit Hazan, and Haoping Liu. "Temporal and Spatial Control of HGC1 Expression Results in Hgc1 Localization to the Apical Cells of Hyphae in Candida albicans." Eukaryotic Cell 6, no. 2 (2006): 253–61. http://dx.doi.org/10.1128/ec.00380-06.

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ABSTRACT The human fungal pathogen Candida albicans can undergo a morphological transition from a unicellular yeast growth form to a multicellular hyphal growth form. During hyphal growth, cell division is asymmetric. Only the apical cell divides, whereas subapical cells remain in G1, and cell surface growth is highly restricted to the tip of the apical cell. Hgc1, a hypha-specific, G1 cyclin-like protein, is essential for hyphal development. Here, we report, using indirect immunofluorescence, that Hgc1 is preferentially localized to the dividing apical cells of hyphae. Hgc1 protein is rapidly
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Hazan, Idit, Marisa Sepulveda-Becerra, and Haoping Liu. "Hyphal Elongation Is Regulated Independently of Cell Cycle inCandida albicans." Molecular Biology of the Cell 13, no. 1 (2002): 134–45. http://dx.doi.org/10.1091/mbc.01-03-0116.

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The mechanism for apical growth during hyphal morphogenesis inCandida albicans is unknown. Studies fromSaccharomyces cerevisiae indicate that cell morphogenesis may involve cell cycle regulation by cyclin-dependent kinase. To examine whether this is the mechanism for hyphal morphogenesis, the temporal appearance of different spindle pole body and spindle structures, the cell cycle-regulated rearrangements of the actin cytoskeleton, and the phosphorylation state of the conserved Tyr19 of Cdc28 during the cell cycle were compared and found to be similar between yeast and serum-induced hyphal api
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Su, Chang, Yandong Li, Yang Lu, and Jiangye Chen. "Mss11, a Transcriptional Activator, Is Required for Hyphal Development in Candida albicans." Eukaryotic Cell 8, no. 11 (2009): 1780–91. http://dx.doi.org/10.1128/ec.00190-09.

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ABSTRACT Candida albicans undergoes a morphological transition from yeast to hyphae in response to a variety of stimuli and growth conditions. We previously isolated a LisH domain containing transcription factor Flo8, which is essential for hyphal development in C. albicans. To search the putative binding partner of Flo8 in C. albicans, we identified C. albicans Mss11, a functional homolog of Saccharomyces cerevisiae Mss11, which also contains a LisH motif at its N terminus. C. albicans Mss11 can interact with Flo8 via the LisH motif by in vivo coimmunoprecipitation. The results of a chromatin
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Felk, Angelika, Marianne Kretschmar, Antje Albrecht, et al. "Candida albicans Hyphal Formation and the Expression of the Efg1-Regulated Proteinases Sap4 to Sap6 Are Required for the Invasion of Parenchymal Organs." Infection and Immunity 70, no. 7 (2002): 3689–700. http://dx.doi.org/10.1128/iai.70.7.3689-3700.2002.

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ABSTRACT The ability to change between yeast and hyphal cells (dimorphism) is known to be a virulence property of the human pathogen Candida albicans. The pathogenesis of disseminated candidosis involves adhesion and penetration of hyphal cells from a colonized mucosal site to internal organs. Parenchymal organs, such as the liver and pancreas, are invaded by C. albicans wild-type hyphal cells between 4 and 24 h after intraperitoneal (i.p.) infection of mice. In contrast, a hypha-deficient mutant lacking the transcription factor Efg1 was not able to invade or damage these organs. To investigat
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Fuchs, Uta, Isabel Manns, and Gero Steinberg. "Microtubules Are Dispensable for the Initial Pathogenic Development but Required for Long-Distance Hyphal Growth in the Corn Smut FungusUstilago maydis." Molecular Biology of the Cell 16, no. 6 (2005): 2746–58. http://dx.doi.org/10.1091/mbc.e05-03-0176.

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Fungal pathogenicity often involves a yeast-to-hypha transition, but the structural basis for this dimorphism is largely unknown. Here we analyze the role of the cytoskeleton in early steps of pathogenic development in the corn pathogen Ustilago maydis. On the plant yeast-like cells recognize each other, undergo a cell cycle arrest, and form long conjugation hyphae, which fuse and give rise to infectious filaments. F-actin is essential for polarized growth at all these stages and for cell-cell fusion. Furthermore, F-actin participates in pheromone secretion, but not perception. Although U. may
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Liu, Guiqing, Li Cao, Xuehong Qiu, and Richou Han. "Quorum Sensing Activity and Hyphal Growth by External Stimuli in the Entomopathogenic Fungus Ophiocordyceps sinensis." Insects 11, no. 4 (2020): 205. http://dx.doi.org/10.3390/insects11040205.

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The entomopathogenic fungus Ophiocordyceps sinensis is one of the best known and most precious medicines and health food in China. The blastospores-hyphae (dimorphism) transition of this fungus in host hemolymph is critical for the virulence and the mummification of host larvae. To regulate this transition, the effects of inoculum density and fifteen chemicals including fungal nutrients, fungal metabolites, quorum-sensing molecules (QSMs) and insect hormones on the dimorphism in O. sinensis were investigated in vitro. The blastospores tended to exhibit budding growth when inoculated at 107 bla
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Rida, Padmashree C. G., Akiko Nishikawa, Gena Y. Won, and Neta Dean. "Yeast-to-Hyphal Transition Triggers Formin-dependent Golgi Localization to the Growing Tip inCandida albicans." Molecular Biology of the Cell 17, no. 10 (2006): 4364–78. http://dx.doi.org/10.1091/mbc.e06-02-0143.

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Rapid and long-distance secretion of membrane components is critical for hyphal formation in filamentous fungi, but the mechanisms responsible for polarized trafficking are not well understood. Here, we demonstrate that in Candida albicans, the majority of the Golgi complex is redistributed to the distal region during hyphal formation. Randomly distributed Golgi puncta in yeast cells cluster toward the growing tip during hyphal formation, remain associated with the distal portion of the filament during its extension, and are almost absent from the cell body. This restricted Golgi localization
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Dissertations / Theses on the topic "Hyphal transition"

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Gilfillan, Gregor D. "Virulence and signal transduction of hypha formation in Candida albicans." Thesis, University of Aberdeen, 1999. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU112191.

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The aims of this work were to investigate the signal transduction pathways controlling the yeast-hyphal morphological transition of Candida albicans, and to gain a clearer understanding of the importance of hyphal formation of the virulence of this organism. The work can be divided into two areas. Firstly, the recently discovered species Candida dubliniensis, the only species in addition to C. albicans capable of forming true non-constricted hyphae, was examined in comparison to C. albicans to compare their virulence capability in vitro and in vivo. The two species were compared with respect t
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Malek, Reine. "Etude des médiateurs moléculaires des interactions microbiennes de la levure Yarrowia lipolytica avec les micro-organismes de son environnement biotique." Thesis, Paris, AgroParisTech, 2012. http://www.theses.fr/2012AGPT0061.

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Les écosystèmes microbiens sont composés d'une grande diversité de micro-organismes dans lesquels des interactions inter-espèces et intra-espèces se mettent en place. La compréhension et la maîtrise de ces écosystèmes représentent un enjeu scientifique, sanitaire et économique et passent par l'identification et la compréhension des interactions qui régissent leur fonctionnement. L'étude de l'interaction entre deux levures fromagères Yarrowia lipolytica et Debaryomyces hansenii, a montré une inhibition de la croissance de D. hansenii en présence de Y. lipolytica. L'étude transcriptomique nous a
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Lacroix, Céline. "Nrg1p and Rfg1p in Candida albicans yeast-to-hyphae transition." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=112528.

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The ability of Candida albicans to change morphology plays several roles in its virulence and as a human commensal. The yeast-to-hyphae transition is tightly regulated by several sets of activating and repressing pathways. The DNA-binding proteins Rfg1p, Nrg1p and the global repressor Tup1p are part of the repressors found to regulate this morphogenesis. Knowledge of these repressors is based on extrapolations from homology to S. cerevisiae and from expression studies of mutants in inducing conditions, all of which are indirect means of determining a protein's function. We proposed a genome-wi
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Shareck, Julie. "Effect of fatty acids on hyphal growth in the pathogenic yeast Candida albicans." Thèse, 2011. http://hdl.handle.net/1866/5494.

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Candida albicans est une levure pathogène qui, à l’état commensal, colonise les muqueuses de la cavité orale et du tractus gastro-intestinal. De nature opportuniste, C. albicans cause de nombreuses infections, allant des candidoses superficielles (muguet buccal, vulvo-vaginite) aux candidoses systémiques sévères. C. albicans a la capacité de se développer sous diverses morphologies, telles que les formes levures, pseudohyphes et hyphes. Des stimuli environnementaux mimant les conditions retrouvées chez l’hôte (température de 37°C, pH neutre, présence de sérum) induisent la transition levure-à-
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Book chapters on the topic "Hyphal transition"

1

Vanden Bossche, Hugo, and Patrick Marichal. "Is there a Role for Sterols and Steroids in Fungal Growth and Transition from Yeast to Hyphal-Form and Vice Versa? An Overview." In Dimorphic Fungi in Biology and Medicine. Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-2834-0_15.

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Domínguez, Angel. "Induction of the Yeast-Hypha Transition in Yarrowia lipolytica." In Non-Conventional Yeasts in Genetics, Biochemistry and Biotechnology. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-642-55758-3_55.

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Journal articles
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