Academic literature on the topic 'Hypoglycaemic agents'

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Journal articles on the topic "Hypoglycaemic agents"

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Mohajan, Devajit, and Haradhan Kumar Mohajan. "Oral Hypoglycaemic Agents: Non-Insulin Medications for Type 2 Diabetes Patients." Innovation in Science and Technology 3, no. 1 (2024): 23–31. http://dx.doi.org/10.56397/ist.2024.01.04.

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Among type 2 diabetes (T2D) patients, oral medications are called oral hypoglycaemic agents (OHAs), which are preferred over injections due to convenience and acceptability. These are a group of drugs that have been used successfully worldwide for controlling T2D patients to reduce the high blood sugar. These can be classified as either hypoglycaemic agents, such as sulfonylureas and benzoic acid derivatives or antihyperglycaemic agents, such as Biguanides, α-glucosidase inhibitors, and Thiazolidinediones. Most of these stimulate β-cells of the Islets of Langerhans within the pancreas to produ
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Kermode, Allan G., Karen M. McNally, and David A. Joyce. "Sulphonylurea hypoglycaemic agents." Medical Journal of Australia 157, no. 10 (1992): 717–20. http://dx.doi.org/10.5694/j.1326-5377.1992.tb137447p.x.

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Marshall, SM. "Oral hypoglycaemic agents." Practical Diabetes International 20, no. 7 (2003): S1—S4. http://dx.doi.org/10.1002/pdi.524.

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*, Dr. N. Tendu Pranadeep Dr. G. Gayathri Dr. B.Kavya Chowdary Dr.M.Anuhya Dr.C. Pradeep Dr. G. V. Nagaraju Dr.Md.K.Rahman Dr. Alias Kenny. "SAFETY AND EFFICACY OF TENELIGLIPTIN OVER OTHER HYPOGLYCEMIC AGENTS IN TYPE-2 DIABETES." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 07 (2018): 6325–40. https://doi.org/10.5281/zenodo.1310608.

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To compare the safety and efficacy of the Teneligliptin a DPP inhibitor over other hypoglycaemic agents in Type II Diabetes Mellitus. .It is a prospective –observational study in this study was conducted at, Pradeep Diabetic Centre, Rajamahendravaram and the study was carried out for a period of 6 months from Feb 2016 to July 2016, and we are taking total of 114 patients with type 2 diabetes, in our study concludes the combination of Teneligliptin with other oral hypoglycaemic agents have been shown to improve glycaemic control efficiently when compare with the monotherapy shown inadequa
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MacMahon, Clare, Millie O'Gorman, John Martin, et al. "249 Is Our Diabetic Control Too Tight? An Audit of Management of Type II Diabetes in a Long Term Care Setting." Age and Ageing 48, Supplement_3 (2019): iii17—iii65. http://dx.doi.org/10.1093/ageing/afz103.153.

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Abstract Background Recent guidelines on diabetes management recommend individualisation of management particularly in those with frailty or significant co-morbidities. The aim of our audit was to assess diabetic control of residents in a long term care setting. Studies have shown that intensive control in an older population increases the risk of hypoglycaemia and does not necessarily improve clinical outcomes. There is also evidence that increased pill burden and hypoglycaemic events negatively affect quality of life among older people. Methods 176 nursing home residents were assessed. Detai
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Dr., Syed Farasat Ali Shah Dr. Eesha Noor Dr. Ifaza Tariq. "TO DETERMINE THE FREQUENCY OF HYPOGLYCAEMIA IN DIABETIC PATIENTS TAKING ORAL HYPOGLYCAEMIC DRUGS/ INSULIN." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 11 (2018): 12376–81. https://doi.org/10.5281/zenodo.1490073.

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<strong><em>Background: </em></strong><em>The risk of severe hypoglycemia is greatly increased in subjects having old age, renal failure, hepatic failure and pregnancy. The overall prevalence is 2&ndash;3%, and the lifetime risk is around 15%. </em> <strong><em>Objective: </em></strong><em>To determine the frequency of hypoglycemia in diabetic subjects taking oral hypoglycemic agents/ Insulin therapy.</em> <strong><em>Method: </em></strong><em>This cross-sectional study includes 250 out/in patient type 2 diabetic subjects visiting to Pakistan Institute of Medical Sciences that is a tertiary ca
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Ntouva, Antiopi, Konstantinos A. Toulis, Deepikshana Keerthy, et al. "Hypoglycaemia is associated with increased risk of fractures in patients with type 2 diabetes mellitus: a cohort study." European Journal of Endocrinology 180, no. 1 (2019): 51–58. http://dx.doi.org/10.1530/eje-18-0458.

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Objective Type 2 diabetes is associated with an increased risk of fracture. Any factor that incrementally increases this risk should be taken into account when individualising treatment. Hypoglycaemia is a common complication of antidiabetes medications and suggested as a risk factor for fractures; yet, its real-life clinical impact is unclear. Design A population-based, retrospective open cohort study using routinely collected data between 1st of January 1995 and 1st of May 2016 in The Health Improvement Network (THIN) database. Methods Patients with type 2 diabetes mellitus with documented h
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Rosskamp, R. "Safety aspects of oral hypoglycaemic agents." Diabetologia 39, no. 12 (1996): 1668–72. http://dx.doi.org/10.1007/s001250050632.

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Batra, Chandar M., Kiran Kumar, and Monica Goyal. "D1 MTE1 Case 1: Steroid refractory insulin autoimmune syndrome treated with rituximab and continuous glucose monitoring." Indian Journal of Endocrinology and Metabolism 26, Suppl 1 (2022): S1. http://dx.doi.org/10.4103/2230-8210.342324.

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A 67-year-old female presented with severe hypoglycaemia with a blood glucose of 34mg/dl 5 hours after having dinner. She did not have diabetes and had no access to oral hypoglycaemic agents, insulin, or any other drug known to cause hypoglycaemia. She was a known case of primary hypothyroidism euthyroid on treatment. The physical examination was unremarkable. Her liver, renal functions, thyroid, and adrenal functions were normal. At blood sugar of 23 mg/dl, her serum insulin was 24000uU/ml (normal&lt;3uU/ml) and c-peptide was 16.2 ng/ml (normal 0-0.6ng/ml) which were very high. As the serum i
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Mkele, Gail. "Where do sulphonylureas fit in the type 2 diabetes guidelines?" South African Family Practice 56, no. 4 (2014): 2. http://dx.doi.org/10.4102/safp.v56i4.4190.

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Sulphonylureas act by binding to sulphonylurea receptors and stimulating insulin secretion from pancreatic beta cells. This class of oral hypoglycaemic agents is still widely used in the management of type 2 diabetes in patients where lifestyle changes alone are insufficient. Although the older-generation sulphonylureas no longer have a place in therapy, the newer-generation sulphonylureas are a widely recognised choice, either as monotherapy, or in combination with insulin and/or other oral hypoglycaemic agents.
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Dissertations / Theses on the topic "Hypoglycaemic agents"

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Aloudah, Nouf Mohammad. "Oral hypoglycaemic medication adherence in Saudi Arabia." Thesis, University of Aberdeen, 2016. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=231048.

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Diabetes has been labelled as one of the largest crises in the twenty-first century. Saudi Arabia is one of the top 10 countries for prevalence of diabetes and one in five people has the condition. Medication adherence assessment is vital to help clinicians reach therapy outcomes and identify gaps in patient management. The aim of this PhD was to explore oral hypoglycaemic medication (OHM) adherence in patients with Type 2 diabetes patients in Saudi Arabia and to identify factors associated with OHM adherence. The aim was addressed by: 1) Conducting a systematic review to identify which tools
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Chu, Qingwei. "In vivo effects of peroxoVanadium (pV) compounds as hypoglycaemic agents." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0025/MQ37109.pdf.

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Pellerin, Marieve. "Diabète gestationnel : insuline ou hypoglycémiants oraux ? Étude pilote de la préférence des femmes et de l'influence du traitement sur la qualité de vie." Mémoire, Université de Sherbrooke, 2015. http://hdl.handle.net/11143/8036.

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Résumé : Introduction : Le débat sur l’utilisation des hypoglycémiants oraux (HGO) dans le traitement du diabète gestationnel (DG) perdure. Plusieurs études ont montré que la metformine et le glyburide sont deux alternatives acceptables en grossesse. Malgré tout, l’insuline reste le choix de première intention pour le traitement du DG lorsque la diète et l’exercice physique ne suffisent plus. Les principaux arguments en faveur des HGO sont la possibilité d’une meilleure observance du traitement et une meilleure qualité de vie (QDV). Cependant, les études sur la QDV chez les femmes atteintes de
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"Combined therapy with oral hypoglycaemic agents compared to insulin therapy alone in Hong Kong Chinese patients with non-insulin dependent diabetes mellitus." 1997. http://library.cuhk.edu.hk/record=b5889155.

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by Lynn Wah Wong Tsang.<br>Consent form in Chinese.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 1997.<br>Includes bibliographical references (leaves 127-145).<br>Declaration --- p.i<br>Acknowledgments --- p.ii<br>Table of Contents --- p.iii<br>List of Tables --- p.vii<br>List of Figures --- p.x<br>List of Appendix --- p.xi<br>Chapter CHAPTER1 --- INTRODUCTION<br>Chapter 1.1 --- General Introduction --- p.2<br>Chapter 1.2 --- Literature Review --- p.6<br>Chapter 1.2.1 --- Classifications of Diabetes Mellitus --- p.6<br>Chapter 1.2.2 --- Diagnostic Criteria of Diabetes Mellitu
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Books on the topic "Hypoglycaemic agents"

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Miles, Fisher B., and Frier Brian M, eds. Hypoglycaemia in clinical diabetes. John Wiley, 1999.

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Frier, Brian M., Simon Heller, and Rory McCrimmon. Hypoglycaemia in Clinical Diabetes. Wiley & Sons, Incorporated, John, 2013.

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Fisher, Miles, and Brian M. Frier. Hypoglycaemia in Clinical Diabetes. Wiley & Sons, Incorporated, John, 2007.

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Frier, Brian M., Simon Heller, and Rory McCrimmon. Hypoglycaemia in Clinical Diabetes. Wiley & Sons, Limited, John, 2013.

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(Editor), Brian M. Frier, and Miles Fisher (Editor), eds. Hypoglycaemia in Clinical Diabetes (Practical Diabetes). 2nd ed. Wiley-Interscience, 2007.

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van Hooijdonk, Roosmarijn T. M., and Marcus J. Schultz. Insulin and oral anti-hyperglycaemic agents in critical illness. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0050.

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Dysglycaemia is frequently seen in the intensive care unit (ICU). Hyperglycaemia, hypoglycaemia and glycaemic variability are all independently associated with mortality and morbidity in critically-ill patients. It is common practice to treat hypergycaemia in these patients, while at the same time preventing hypoglycaemia and glycaemic variability. Insulin infusion is preferred over oral anti–hyperglycaemic agents for glucose control in the ICU because of the highly unpredictable biological availability of oral anti-hyperglycaemic agents during critical illness. Many oral anti–hyperglycaemic a
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Guire, Michelle Mc. The influence of streptozotcin diabetes and the hypoglycaemic agent metformin on rat skeletal muscles. 1997.

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Bleck, Thomas P. Pathophysiology and causes of seizures. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0231.

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Seizures result from imbalances between excitation and inhibition, and between neuronal synchrony and dyssynchrony. Current models implicate the cerebral cortex in the genesis of seizures, although thalamic mechanisms (particularly the thalamic reticular formation) are involved in the synchronization of cortical neurons. Often, the precipitants of a seizure in the critical care setting are pharmacological. Several mechanisms linked to critical illness can lead to seizures. Failure to remove glutamate and potassium from the extracellular space, functions performed predominantly by astrocytes, o
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Bleck, Thomas P. Assessment and management of seizures in the critically ill. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0232.

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In previously conscious patients seizures are usually easily detected. Critically-ill patients are frequently sedated and a proportion are paralysed with neuromuscular blocking agents, in such patients it may be hard or impossible to detect seizures clinically. An urgent electroencephalogram (EEG) should be obtained whenever seizures are witness or suspected, especially if the patient does not rapidly return to baseline, when non-convulsive status epilepticus must be excluded. Unless the cause of the seizure activity is already known, an urgent CT, or MRI is indicated. If central nervous syste
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Wilton, Niall, Brian J. Anderson, and Bruno Marciniak. Anatomy, physiology, and pharmacology in paediatric anaesthesia. Edited by Jonathan G. Hardman and Neil S. Morton. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0069.

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Anaesthesia for children is tempered by changes that occur during both growth and development. Drug dose is affected by size and clearance maturation processes as well as the changing body composition that occurs with age. All organ systems undergo these maturation changes and most are complete within the first few years of life. Normal physiological variables in infancy and childhood are quite different from adults. The central nervous, cardiovascular, and respiratory systems are particularly important. Cerebral immaturity and plasticity impacts sensitivity to drugs, pain responses, and behav
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Book chapters on the topic "Hypoglycaemic agents"

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McCombe, Kate, and Lara Wijayasiri. "Hypoglycaemic Agents." In The Primary FRCA Structured Oral Examination Study Guide 2, 3rd ed. CRC Press, 2025. https://doi.org/10.1201/9781003276470-35.

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Touber, J. L. "Introduction: Diet and hypoglycaemic agents." In Pathogenesis and Treatment of Diabetes Mellitus. Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-009-4301-8_10.

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Watson, K. A. "In Search of Hypoglycaemic Agents for the Treatment of Non-Insulin Dependent Diabetes Mellitus." In Structure-Based Drug Design. Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-015-9028-0_17.

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"Hypoglycaemic Agents." In The Primary FRCA Structured Oral Examination Study Guide 2. CRC Press, 2017. http://dx.doi.org/10.1201/9781315383293-33.

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"Hypoglycaemic Agents." In Encyclopedia of Molecular Pharmacology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-57401-7_300274.

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Hulin, Bernard. "1 New Hypoglycaemic Agents." In Progress in Medicinal Chemistry. Elsevier, 1994. http://dx.doi.org/10.1016/s0079-6468(08)70018-3.

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"Oral hypoglycaemic treatment." In Practical Diabetes Care, edited by Rowan Hillson. Oxford University PressNew York, NY, 2002. http://dx.doi.org/10.1093/oso/9780192632906.003.0008.

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Abstract Consider oral hypoglycaemic drugs for patients whose blood glucose control is poor despite dietary effort (see Table 8.1), and who do not require insulin injections. Set individual targets for blood glucose or glycosylated haemoglobin taking the patient’ s overall clinical and mental state, and home circumstances into consideration. A strict glucose balance is not always appropriate in a very elderly person living alone, for example. Oral hypoglycaemic agents work only if the patient has some residual insulin production. They should be avoided in patients with Type 1 diabetes for whom
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Steiner, Kurt E., and Eric L. Lien. "6 Hypoglycaemic Agents Which Do Not Release Insulin." In Progress in Medicinal Chemistry. Elsevier, 1987. http://dx.doi.org/10.1016/s0079-6468(08)70423-5.

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Ramrakha, Punit S., Kevin P. Moore, and Amir H. Sam. "Drug overdoses." In Oxford Handbook of Acute Medicine. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780198797425.003.0014.

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This chapter describes drug overdoses, the general approach, and antidotes. It includes information on overdoses of anticonvulsants, antipsychotic drugs, aspirin, benzodiazepines, beta-blockers, calcium channel blockers, carbon monoxide, cyanide, digoxin, ethanol, hypoglycaemic agents, iron, lithium, non-steroidal anti-inflammatory drugs, recreational drugs (stimulants: amphetamines, cocaine; hallucinogens: ketamine, magic mushrooms; depressants: opioids, GHB/GBL), paracetamol, selective serotonin reuptake inhibitors (SSRIs), toxic alcohols, and tricyclic antidepressants.
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Bahn Kawa, Leslie. "Management of Type 2 DiabetesMellitus." In Type 2 Diabetes - From Diagnosis to Effective Management [Working Title]. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.1002478.

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Type 2 diabetes mellitus is a complex metabolic disease with complex derangements of metabolic pathways that are involved in the glucose metabolism in different organs: the liver, muscles, pancreas, the gut, kidneys, fat cells and the brain. The objectives of the treatment of Type 2 diabetes mellitus are to reverse the underlying eight pathophysiologies called the ‘ominous octet’, achieve glycaemic control, control comorbidities and prevent or reduce the chronic complications. Lifestyle management and pharmacotherapy remain the mainstay of treatment of Type 2 diabetes mellitus. The development
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