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Journal articles on the topic 'Hypoglycemic and hypolipidemic effects'

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Published: 7 June 2025

Last updated: 2 August 2025

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1

Abousamra, Mona M., Mona Basha, Sally El Awdan та Nasser S. M. Ismail. "EFFECT OF METHYL-Β-CYCLODEXTRIN COMPLEXATION ON THE HYPOGLYCEMIC AND HYPOLIPIDEMIC EFFECTS OF KHELLIN: EXPERIMENTAL STUDY". International Journal of Pharmacy and Pharmaceutical Sciences 8, № 11 (2016): 165. http://dx.doi.org/10.22159/ijpps.2016v8i11.14365.

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Objective: The present work tackled the development and evaluation of inclusion complex of khellin (KH) and methyl-β-cyclodextrin (MβCD). In addition, it tested its possible hypoglycemic and hypolipidemic effects.Methods: Inclusion complexes of KH-MβCD in the presence of water-soluble polymer were prepared by freeze drying (FD), co-evaporation (EV) and kneading methods (KN). The selected ternary complex was characterized by Fourier transform infrared spectrophotometry (FTIR), x-ray diffractometry (XRD), differential scanning calorimetry (DSC) and scanning electron microscopy [1]. Assessment of

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Joseph, P. K., and R. T. Kasinath. "Hypoglycemic and hypolipidemic effects of diacetodibutyl disulphide." Indian Journal of Clinical Biochemistry 15, no. 2 (2000): 68–75. http://dx.doi.org/10.1007/bf02883731.

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Wang, Kaiping, Peng Cao, Weizhi Shui, Qiuxiang Yang, Zhuohong Tang, and Yu Zhang. "Angelica sinensis polysaccharide regulates glucose and lipid metabolism disorder in prediabetic and streptozotocin-induced diabetic mice through the elevation of glycogen levels and reduction of inflammatory factors." Food & Function 6, no. 3 (2015): 902–9. http://dx.doi.org/10.1039/c4fo00859f.

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Habib, M. Anwar, ASM Anisuzzaman, RK Barman, M. Abdul Gafur, and M. Tofazzal Haque. "Isolation and Characterization of Hypolipidemic Compound from Cajanus cajan." TAJ: Journal of Teachers Association 24, no. 1 (2011): 6–10. http://dx.doi.org/10.3329/taj.v24i1.37441.

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The study was carried out to identify the compound responsible for hypolipidemic and hypoglycemic effects of Cajanus cajan (redgram). The methanol extract of redgram seeds was found to decrease fasting blood glucose and lipid profile (p<0.001) on streptozotocin-induced mice compared to control. This activity- guided fraction led to the isolation of a compound, substituted benzene containing polyhydroxy functions fused with lactone (CCA3) by analysis of 1H and 13C-NMR data. Biological studies of the isolated compound possessed prominent hypolipidemic activity. Although a number of hypoglycem

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Tu, Lanlan, Rui Wang, Zheng Fang, et al. "Assessment of the Hypoglycemic and Hypolipidemic Activity of Flavonoid-Rich Extract from Angelica keiskei." Molecules 27, no. 19 (2022): 6625. http://dx.doi.org/10.3390/molecules27196625.

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Angelica keiskei contains a variety of bioactive compounds including chalcone, coumarin, and phytochemicals, endowing it with pharmacological effects such as lipid-lowering activity, antitumor activity, liver protection, and nerve protection. This study aims to study the hypoglycemic and hypolipidemic effects of the flavonoid-rich extract from Angelica keiskei (FEAK) in an effort to exploit new applications of FEAK and increase its commercial value. In this paper, flavonoid compounds in Angelica keiskei were extracted using 50% ethanol, and the contents of the flavonoid compounds were analyzed

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Zhou, Ji-Yin, Shi-Wen Zhou, Sheng-Ya Zeng, Jian-Yun Zhou, Ming-Jin Jiang, and Yan He. "Hypoglycemic and Hypolipidemic Effects of Ethanolic Extract ofMirabilis jalapaL. Root on Normal and Diabetic Mice." Evidence-Based Complementary and Alternative Medicine 2012 (2012): 1–9. http://dx.doi.org/10.1155/2012/257374.

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The present study investigated the insulin sensitivity, hypoglycemic, and hypolipidemic activities of ethanolic extract ofMirabilis jalapaL. root (EEM) in normal and diabetic mice. After induction of diabetes with streptozotocin, both normal and diabetic mice were singly or repeatedly for 28 days administrated with EEM at doses of 2, 4, 8 g/kg, respectively. Before induction of diabetes, mice were administrated with EEM at doses of 2, 4, 8 g/kg for 14 days and were injected with streptozotocin and continued on EEM administration for another 28 days. Both after and before induction of diabetes,

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Xu, Jialin, Tingting Liu, Yuanyuan Li, et al. "Hypoglycemic and hypolipidemic effects of triterpenoid-enriched Jamun (Eugenia jambolana Lam.) fruit extract in streptozotocin-induced type 1 diabetic mice." Food & Function 9, no. 6 (2018): 3330–37. http://dx.doi.org/10.1039/c8fo00095f.

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Jia, Sheng, Ying Hu, Wenna Zhang, et al. "Hypoglycemic and hypolipidemic effects of neohesperidin derived from Citrus aurantium L. in diabetic KK-Aymice." Food & Function 6, no. 3 (2015): 878–86. http://dx.doi.org/10.1039/c4fo00993b.

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Chen, Zhongqin, Cong Wang, Yuxiang Pan, Xudong Gao, and Haixia Chen. "Hypoglycemic and hypolipidemic effects of anthocyanins extract from black soybean seed coat in high fat diet and streptozotocin-induced diabetic mice." Food & Function 9, no. 1 (2018): 426–39. http://dx.doi.org/10.1039/c7fo00983f.

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10

Yang, Chang, Qi Feng, Huan Liao, Xinlei Yu, Yang Liu та Di Wang. "Anti-Diabetic Nephropathy Activities of Polysaccharides Obtained from Termitornyces albuminosus via Regulation of NF-κB Signaling in db/db Mice". International Journal of Molecular Sciences 20, № 20 (2019): 5205. http://dx.doi.org/10.3390/ijms20205205.

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Termitornyces albuminosus is a kind of traditional Chinese edible fungus rich in nutrients and medicinal ingredients, and it has anti-oxidative, analgesic and anti-inflammatory effects. However, the hypoglycemic and nephroprotective effects of polysaccharides separated from T. albuminosus (PTA) have not been reported. The properties of PTA were analyzed in a BKS.Cg-Dock7m +/+ Leprdb/JNju (db/db) mouse model of diabetes. After the administration of PTA for eight weeks, the hypoglycemic and hypolipidemic activities of PTA in the db/db mice were assessed. The results of a cytokine array combined

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Ou, Juanying, Junqing Huang, Danyue Zhao, Bin Du, and Mingfu Wang. "Protective effect of rosmarinic acid and carnosic acid against streptozotocin-induced oxidation, glycation, inflammation and microbiota imbalance in diabetic rats." Food & Function 9, no. 2 (2018): 851–60. http://dx.doi.org/10.1039/c7fo01508a.

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12

Pothuraju, Ramesh, Raj Kumar Sharma, Suneel Kumar Onteru, Satvinder Singh, and Shaik Abdul Hussain. "Hypoglycemic and Hypolipidemic Effects ofAloe veraExtract Preparations: A Review." Phytotherapy Research 30, no. 2 (2015): 200–207. http://dx.doi.org/10.1002/ptr.5532.

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13

Schneider, Mariane, Adrieli Sachett, Amanda P. Schönell, et al. "Hypoglycemic and hypolipidemic effects of Solidago chilensis in rats." Revista Brasileira de Farmacognosia 25, no. 3 (2015): 258–63. http://dx.doi.org/10.1016/j.bjp.2015.05.001.

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14

Liu, Yangyang, Chaorui Wang, Jinshan Li, Yuxia Mei, and Yunxiang Liang. "Hypoglycemic and Hypolipidemic Effects of Phellinus Linteus Mycelial Extract from Solid-State Culture in A Rat Model of Type 2 Diabetes." Nutrients 11, no. 2 (2019): 296. http://dx.doi.org/10.3390/nu11020296.

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Hypoglycemic and hypolipidemic effects of P. linteus have been observed in numerous studies, but the underlying molecular mechanisms are unclear. In this study, we prepared P. linteus extract (PLE) from mycelia of solid-state culture, and evaluated its hypoglycemic and hypolipidemic effects in rat models of high-fat diet (HFD)-induced and low-dose streptozotocin (STZ)-induced type 2 diabetes. PLE treatment effectively reduced blood glucose levels, and improved insulin resistance and lipid and lipoprotein profiles. The hypoglycemic effect of PLE was based on inhibition of key hepatic gluconeoge

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15

Sovia, E., W. Ratwita, D. Wijayanti, and D. R. Novianty. "HYPOGLYCEMIC AND HYPOLIPIDEMIC EFFECTS OF ANNONA MURICATA L. LEAF ETHANOL EXTRACT." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 3 (2017): 170. http://dx.doi.org/10.22159/ijpps.2017v9i3.16402.

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Objective: The aim of this study was to investigate hypoglycemic and hypolipidemic effects of Annona muricata leaf ethanol extract. This study also investigated phytochemical analysis of the extract and improvement in the islet of Langerhans.Methods: Hypoglycemic and hypolipidemic effects were evaluated using alloxan induced diabetic rats. Twenty-five Wistar rats devided into five groups, that are normal group, control group that induced by alloxan 125 mg/kg body weight and given CMC (carboxymethyl cellulose), and three treatment group that induced by alloxan and given Annona muricata leaf eth

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Wang, Yong, Haiying Wang, and Fengzhen Yang. "Barbaloin Treatment Contributes to the Rebalance of Glucose and Lipid Homeostasis of Gestational Diabetes Mellitus Mice." Dose-Response 18, no. 4 (2020): 155932582098491. http://dx.doi.org/10.1177/1559325820984910.

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Aloe vera L has been shown to possess hypoglycemic and hypolipidemic effects on type 2 diabetic patients, and its major benefits may be linked to barbaloin, which is a major component of Aloe vera L. This study focused on investigating the potential effects and underlying mechanisms of barbaloin on gestational diabetes mellitus (GDM). The db/+ diabetic mice with GDM were daily orally administered with barbaloin or metformin during the gestational period. The results demonstrated that administration of barbaloin significantly reduced blood glucose levels and increased insulin levels in GDM mice

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17

Zhang, Xiaoqian, Jing Fang, Ruipeng Ge, et al. "Regulation of Glucolipid Metabolism in Mice Using Dendrobium huoshanense Extract and PI3k/Akt Signaling Pathway Activation." Journal of Food Biochemistry 2023 (October 31, 2023): 1–12. http://dx.doi.org/10.1155/2023/8878821.

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The present research is carried out to study the hypoglycemic and hypolipidemic effects of the Dendrobium huoshanense C. Z. Tang et S. J. Cheng extract on type 2 diabetic mice. D. huoshanense extract was prepared using the condensation reflux method. The chemical components were separated by UPLC Triple-TOF MS/MS to further identify the components that mainly exerted hypoglycemic and hypolipidemic effects. Type 2 diabetic C57BL/6 mice were induced by a high-fat diet (HFD) followed by intraperitoneal streptozotocin (STZ) and were daily gavaged with different doses of D. huoshanense extract for

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18

Al Mouslem, Abdulaziz K. "Antidiabetic and Hypolipidemic Potentials of Extract of Picris Babylonica in Streptozotocin-Induced Diabetic Model in Rats." Biomedical and Pharmacology Journal 15, no. 1 (2022): 261–67. http://dx.doi.org/10.13005/bpj/2362.

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Objectives: To investigate the hypoglycemic and hypolipidemic potentials of Picris babylonica extract in streptozotocin (STZ) induced diabetes in rats. Methods: Animals were injected with 40mg/kg of STZ to induce diabetes, a common diabetic model. Development of the disease were assessed by measuring blood glucose level 3 days prior systemic administration of STZ and following STZ injection. Animals received 200mg/kg and 400mg/kg of Picris babylonica extract and 0.6mg/kg of glibenclamide, standard, by oral rout for 14 consecutive days. Results: Administration of the Picris babylonica extract s

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19

Rasool, Shahid, Bassam Al Meslmani, and Muaaz Alajlani. "Determination of Hypoglycemic, Hypolipidemic and Nephroprotective Effects of Berberis Calliobotrys in Alloxan-Induced Diabetic Rats." Molecules 28, no. 8 (2023): 3533. http://dx.doi.org/10.3390/molecules28083533.

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Many plants of the Berberis genus have been reported pharmacologically to possess anti-diabetic potential, and Berberis calliobotrys has been found to be an inhibitor of α-glucosidase, α-amylase and tyrosinase. Thus, this study investigated the hypoglycemic effects of Berberis calliobotrys methanol extract/fractions using in vitro and In vivo methods. Bovine serum albumin (BSA), BSA–methylglyoxal and BSA–glucose methods were used to assess anti-glycation activity in vitro, while in vivo hypoglycemic effects were determined by oral glucose tolerance test (OGTT). Moreover, the hypolipidemic and

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20

Dewi, Sri Hartati Candra, Chatarina Wariyah, and Niken Astuti. "Efek hipoglikemik dan hipolipidemik dendeng daging itik curing dengan ekstrak kurkumin kunyit pada Tikus Wistar." Livestock and Animal Research 19, no. 3 (2021): 301. http://dx.doi.org/10.20961/lar.v19i3.48708.

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<p class="MDPI17abstract"><strong>Objective: </strong>This research aimed to determine hypoglycemic and hypolipidemic effects of cured duck meat jerky with curcumin using male Wistar rats as experimental animals.</p><p class="MDPI17abstract"><strong>Methods: </strong>This research involved a completely randomized design in oneway pattern with 4 treatments on diabetic (TD) and hyperlipidemic (HD) rats : zero jerky (standard feed, PS), low jerky 0.96 g/head/day (DR), high jerky 1.91g/head/day (DT) and vitamin E 28.80 mg/head/day as control antioxidants (

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21

R, Ahmed, Jeyabalan G, and Goyal PK. "Evaluation of Hypo-glycemic and Anti-oxidant Potential of Caesalpinia sappan Leave in STZ Induced Diabetic Rats." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 04 (2024): 945–47. https://doi.org/10.25258/ijddt.14.4.2.

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In southern Asia, including India, Sri Lanka, and other countries, the stem bark, root, and leaves of Caesalpinia Sappan (Fabaceae) have been utilized in traditional medical systems to cure diabetes and numerous other illnesses. The hypoglycemic and hypolipidemic potential of this valued plant's leaves and bark, however, has not yet been proven by science. The current study's objective is to assess the hypoglycemic and hypolipidemic effects of Caesalpinia Sappan leaf ethanol extracts. Hydro-alcoholic extracts in dose 200mg/kg of Caesalpinia Sappan leaves (CSL) was evaluated for hypo-glycemic e

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22

Pei, Fangyi, Yuze Lv, Xinbo Cao, Xuemeng Wang, Yanxin Ren, and Jingping Ge. "Structural Characteristics and the Antioxidant and Hypoglycemic Activities of a Polysaccharide from Lonicera caerulea L. Pomace." Fermentation 8, no. 9 (2022): 422. http://dx.doi.org/10.3390/fermentation8090422.

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In this study, a novel polysaccharide, LPP, was obtained from Lonicera caerulea L. pomace by ultrasonic-assisted heating and was purified by Sephadex G-100. The structural characteristics of LPP showed that the molecular weight (Mw) was 8.53 × 104 Da; that it was mainly composed of galacturonic acid, followed by galactose; that it possessed the characteristic functional groups of polysaccharides; and that it had an absence of O-glycosidic bonds and crystalline and triple helix structures. Furthermore, LPP exhibited a favorable thermodynamic stability and antioxidant, hypoglycemic, and hypolipi

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23

Zhao, Rong, Rui Jin, Yong Chen, and Feng-mei Han. "Hypoglycemic and Hypolipidemic Effects of Lycium barbarum Polysaccharide in Diabetic Rats." Chinese Herbal Medicines 7, no. 4 (2015): 310–15. http://dx.doi.org/10.1016/s1674-6384(15)60057-0.

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Al Ani, Khudhair A. M. Abed, and Duraid A. Abbas. "Evaluation of the Effect of Bromocriptine and Sitagliptin and Their Combination on Lipid Profile and Inflammatory Parameters in Induced Type 2 Diabetes Mellitus (T2DM) in Male Albino Rat." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 12, no. 03 (2022): 1422–27. http://dx.doi.org/10.25258/ijddt.12.3.82.

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The current study aimed to investigate the hypolipidemic and anti-inflammatory effects of recently used hypoglycemic drugs bromocriptine and sitagliptine alone and combined dosing regimen on induced type 2 diabetes mellitus (T2DM) in albino rats. Forty adult male rats divided equally into five groups including four diabetic groups and one non-diabetic representing control negative.

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Ogechukwu Celestina Iloka, Chinecherem Christiana Maduka, Chidimma Ozoemena Nweke, and Rebecca Nkiru Sampson. "Phytochemical composition, acute toxicity, hypoglycemic and hypolipidemic effects of ethanol extract of Allium sativum (garlic) bulb in male Wistar rats." World Journal of Advanced Research and Reviews 20, no. 2 (2023): 144–56. http://dx.doi.org/10.30574/wjarr.2023.20.2.1984.

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Allium sativum (garlic) has been used in traditional medicine in Nigeria in the treatment of various ailments such as cold, cough, and microbial infections; and there have been various claims about its pharmacological activities including anti-inflammatory, antimicrobial, hypoglycemic, hypolipidemic, antioxidant, antidiabetic, and anticancer properties. However, there are insufficient data to back up these claims. It is against this backdrop, this study evaluated the phytochemical composition, acute toxicity, hypoglycaemic and hypolipidemic potentials of ethanol extract of A. sativum bulb in m

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26

Le, Minh Hoang, Huyen Sanh Sam, Duy Toan Pham, Ngoc Chi Lan Nguyen, Ngoc Diem Le, and Tran Nhat Phong Dao. "Ngu-Vi-Tieu-Khat decoction, a Vietnamese traditional medicine, possesses hypoglycemic and hypolipidemic effects on streptozotocin-induced type-2 diabetic rat model." Pharmacia 70, no. 4 (2023): 943–50. http://dx.doi.org/10.3897/pharmacia.70.e108879.

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This study aims to assess the hypoglycemic effects of Ngu-Vi-Tieu-Khat (NVTK) decoction, a traditional Vietnamese medicine, in a rat model of type-2 diabetes. The NVTK decoction was prepared using the maceration method and tested for its hypoglycemic effects by measuring blood glucose levels, insulin resistance indicators, and pancreatic mass. The results showed that NVTK decoction improved diabetes symptoms, increased insulin levels, reduced insulin resistance, restored pancreatic mass, and decreased total cholesterol (TC), triglycerides (TG) and low-density lipoprotein cholesterol (LDL-C) wh

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Le, Minh Hoang, Huyen Sanh Sam, Duy Toan Pham, Ngoc Chi Lan Nguyen, Ngoc Diem Le, and Tran Nhat Phong Dao. "Ngu-Vi-Tieu-Khat decoction, a Vietnamese traditional medicine, possesses hypoglycemic and hypolipidemic effects on streptozotocin-induced type-2 diabetic rat model." Pharmacia 70, no. (4) (2023): 943–50. https://doi.org/10.3897/pharmacia.70.e108879.

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This study aims to assess the hypoglycemic effects of Ngu-Vi-Tieu-Khat (NVTK) decoction, a traditional Vietnamese medicine, in a rat model of type-2 diabetes. The NVTK decoction was prepared using the maceration method and tested for its hypoglycemic effects by measuring blood glucose levels, insulin resistance indicators, and pancreatic mass. The results showed that NVTK decoction improved diabetes symptoms, increased insulin levels, reduced insulin resistance, restored pancreatic mass, and decreased total cholesterol (TC), triglycerides (TG) and low-density lipoprotein cholesterol (LDL-C) wh

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28

Kurian, Gino A. "Hypoglycemic effect of poly-herbal combination in streptozotocin-induced diabetic rats." Bangladesh Journal of Pharmacology 11, no. 2 (2016): 364. http://dx.doi.org/10.3329/bjp.v11i2.24855.

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<p class="Abstract">The present study evaluates the combinatorial effect of a poly-herbal combination with multiple therapeutic effects as a hypoglycemic and hypolipidemic agent. Herbal combination of <em>Salacia oblonga, Tinospora cordifolia, Emblica officinalis, Curcuma longa</em> and <em>Gymnema sylvestre</em> was prepared and administered to streptozotocin (55 mg/kg, i.p.)-induced diabetic rats, at a dose of 100 mg/kg, for four weeks. The poly-herbal combination significantly elevated the plasma insulin (90%) and reduced serum glucose (42%), cholesterol (49%),

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29

Yin, Peipei, Shan Zhao, Siyu Chen, et al. "Hypoglycemic and Hypolipidemic Effects of Polyphenols from Burs of Castanea mollissima Blume." Molecules 16, no. 11 (2011): 9764–74. http://dx.doi.org/10.3390/molecules16119764.

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30

Santos, Enaide Soares, Geraldo Lucas Abrantes Coelho, Yan Kauê Saraiva Fontes Loula, et al. "Hypoglycemic, Hypolipidemic, and Anti-Inflammatory Effects of Beta-Pinene in Diabetic Rats." Evidence-Based Complementary and Alternative Medicine 2022 (May 17, 2022): 1–8. http://dx.doi.org/10.1155/2022/8173307.

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Background. Diabetes is a metabolic disease linked to multiple comorbidities, such as low-grade inflammation. β-pinene, a monoterpene commonly found in aromatic plants, is endowed with anti-inflammatory effect and this fact lead us to investigate the possible hypoglycemic, hypolipidemic and anti-inflammatory effects of the monoterpene in the alloxan-induced diabetes experimental model. Methods. Male Wistar rats (200–250 g) were treated orally with β-pinene (25, 50, 100, and 200 mg/kg) or glibenclamide (5 mg/kg), for seven consecutive days. Diabetes was induced by alloxan (40 mg/kg) through the

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31

Ashiq, Aisha, Saleem Jan, Yar Muhammad Khan, et al. "Hypoglycemic and hypolipidemic effects of Oligomeris linifolia in Alloxan-induced diabetic mice1." Current Trends in Biotechnology and Pharmacy 17, no. 2 (2023): 901–6. http://dx.doi.org/10.5530/ctbp.2023.2.27.

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Xie, Yun-Dong, Ji-Ping Liu, Wei Wang, et al. "3,4-Dihydroxyphenethyl nitrate with nitric oxide releasing, antioxidant, hypoglycemic and hypolipidemic effects." Bioorganic & Medicinal Chemistry Letters 30, no. 15 (2020): 127277. http://dx.doi.org/10.1016/j.bmcl.2020.127277.

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Islam, Dipa, Amdadul Huque, Sheuly, et al. "Hypoglycemic and hypolipidemic effects of Nelumbo nucifera flower in Long-Evans rats." Journal of Herbmed Pharmacology 7, no. 3 (2018): 148–54. http://dx.doi.org/10.15171/jhp.2018.25.

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Aissaoui, Abderrahmane, Soumia Zizi, Zafar H. Israili, and Badiâa Lyoussi. "Hypoglycemic and hypolipidemic effects of Coriandrum sativum L. in Meriones shawi rats." Journal of Ethnopharmacology 137, no. 1 (2011): 652–61. http://dx.doi.org/10.1016/j.jep.2011.06.019.

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Bermudes-Contreras, Juan David, Marcela Verónica Gutiérrez-Velázquez, Eli Amanda Delgado-Alvarado, René Torres-Ricario, and Jorge Cornejo-Garrido. "Hypoglycemic and Hypolipidemic Effects of Triterpenoid Standardized Extract of Agave durangensis Gentry." Plants 14, no. 6 (2025): 894. https://doi.org/10.3390/plants14060894.

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Diabetes mellitus is a chronic, degenerative, and multifactorial disease characterized by hyperglycemia, and at least 537 million people suffered from diabetes in 2021. Agave durangensis Gentry, a species of agave native to the state of Durango, reports phenolic compounds, flavonols, flavonoids, and saponins and could be an alternative for the treatment of diabetes. The aim of this work was to identify the compounds in the leaves of Agave durangensis Gentry and their potential activity in diabetes. The leaf extract of Agave durangensis Gentry (EAD) was characterized by ultra-performance liquid

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Liu, Lina, Yihui Chen, Bei Chen, et al. "Advances in Research on Marine-Derived Lipid-Lowering Active Substances and Their Molecular Mechanisms." Nutrients 15, no. 24 (2023): 5118. http://dx.doi.org/10.3390/nu15245118.

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Hyperlipidemia (HLP) is a metabolic disorder caused by abnormal lipid metabolism. Recently, the prevalence of HLP caused by poor dietary habits in the population has been increasing year by year. In addition, lipid-lowering drugs currently in clinical use have shown significant improvement in blood lipid levels, but are accompanied by certain side effects. However, bioactive marine substances have been shown to possess a variety of physiological activities such as hypoglycemic, antioxidant, antithrombotic and effects on blood pressure. Therefore, the hypolipidemic efficacy of marine bioactive

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Nduka, A. G., A. O. Oluwatoyin, A. O. Temitope, and O. Odutola. "Hypoglycemic and hypolipidemic effects of Corchorus olitorius leaves as a food supplement on rats with alloxan-induced diabet." Ukrainian Biochemical Journal 92, no. 4 (2020): 63–69. http://dx.doi.org/10.15407/ubj92.04.063.

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Tahir, Farah Naz, Hania Ali, and Iqra Taqi. "HYPOLIPIDEMIC AND HYPOGLYCEMIC ACTIVITY OF MEDICINAL PLANTS IN STZ (STREPTOZOTOCIN) INDUCED HYPERLIPIDEMIC RATS AND THEIR ROLE IN HEALTH AND DISEASE." Gomal Journal of Medical Sciences 20, no. 1 (2022): 45–50. http://dx.doi.org/10.46903/gjms/20.01.1078.

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In the past few years, medical plants research focused on a lot by scientists all over the world. Many evidence has been studied to show the potential effects of medicinal plants in the medical field. This is due to the presence of many metabolites in plants that includes flavonoids, tannins, terpenoids, and many hypolipidemic and hypoglycemic agents. This study aims to evaluate various medicinal plants for anti-diabetic and hypolipidemic activity in rats. Diabetes mellitus is one of the most common non communicable diseases present globally and it’s most lethal complication which developed is

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Ogechukwu, Celestina Iloka, Christiana Maduka Chinecherem, Ozoemena Nweke Chidimma, and Nkiru Sampson Rebecca. "Phytochemical composition, acute toxicity, hypoglycemic and hypolipidemic effects of ethanol extract of Allium sativum (garlic) bulb in male Wistar rats." World Journal of Advanced Research and Reviews 20, no. 2 (2023): 144–56. https://doi.org/10.5281/zenodo.12569186.

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<em>Allium sativum</em> (garlic) has been used in traditional medicine in Nigeria in the treatment of various ailments such as cold, cough, and microbial infections; and there have been various claims about its pharmacological activities including anti-inflammatory, antimicrobial, hypoglycemic, hypolipidemic, antioxidant, antidiabetic, and anticancer properties. However, there are insufficient data to back up these claims. It is against this backdrop, this study evaluated the phytochemical composition, acute toxicity, hypoglycaemic and hypolipidemic potentials of ethanol extract of <

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Sharmin, R., M. R. I. Khan, Most A. Akhtar, et al. "Hypoglycemic and Hypolipidemic Effects of Cucumber, White Pumpkin and Ridge Gourd in Alloxan Induced Diabetic Rats." Journal of Scientific Research 5, no. 1 (2012): 161–70. http://dx.doi.org/10.3329/jsr.v5i1.10252.

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Ethanolic extracts of some fruits of Cucurbitaceae family such as Cucumis sativus (cucumber), Lagenaria siceraria (white pumpkin), Luffa acutangula (ridge gourd), Benincasa hispida (ash gourd), Citrullus lanatus (sweet melon) and Cucarbita maxima (pumpkin) have been studied for their hypoglycemic effects on alloxan induced diabetic rats (AIDRs). Screening results suggested that among the tested fruits the hypoglycemic potency follows: cucumber > white pumpkin > ridge gourd. These three fruit-extracts were further investigated for their hypoglycemic, hypolipidemic and glycogenesis effects

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Rahman, Shahid, Gul Jan, Farzana Gul Jan, and Hafeez Ur Rahim. "Phytochemical Investigation and Therapeutical Potential of Cotinus coggygria Scop. in Alloxan-Induced Diabetic Mice." Oxidative Medicine and Cellular Longevity 2022 (December 31, 2022): 1–14. http://dx.doi.org/10.1155/2022/8802178.

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Plants are a significant source for the development of new phytomedicines due to their great clinical benefits, efficiency, cost-effectiveness, fewer side effects, and more affordable therapies. Numerous plants used in traditional treatments, such as Cotinus coggygria Scop., have been effective in the treatment of diabetes mellitus (DM). Therefore, the study is aimed at assessing the phytochemical, antioxidant, and antidiabetic properties of C. coggygria. The hypoglycemic and hypolipidemic activity was evaluated in Swiss male Albino mice by administering an oral dose of 150-250 mg/kg of C. cog

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J, Goje L., Maisamari C.A, F.U Maigari, P.E Ghamba, A.D.T. Goji, and P.P Mshelia. "The Hypoglycemic and Hypolipidemic Effects of the Aqueous Extract of Vernonia Amygdalina Leaves on Alloxan Induced Diabetic Albino Rats." International Journal of Sciences Volume 3, no. 2014-09 (2014): 5–11. https://doi.org/10.5281/zenodo.3348777.

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The study was conducted to determine the hypoglycemic and hypolipidemic effects of the aqueous extract of vernonia amygdalina leaves extract. Healthy albino rats weighing between 200g and 230g were used. The rats were divided in to four different groups each containing five albino rats respectively. Three of the groups (b, c and d) were induced with diabetes by the administration of alloxan monohydrate at a concentration of 150mg/kg through intraperitoneal injection. The fasting blood glucose of the rats and their weights were measured before and after the induction of diabetes using glucose m

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Ahamed, Ridoy, Afifa Parvin Shanta, Israt Jahan Bulbul, Md Mahbubur Rahman Tanim, Md Ruhul Kuddus, and Mohammad A. Rashid. "Hypoglycemic and Hypolipidemic Activities of Bile of Bangladeshi Labeo rohita on Streptozotocin (STZ) - Induced Diabetic Rats." Bangladesh Pharmaceutical Journal 25, no. 1 (2022): 32–37. http://dx.doi.org/10.3329/bpj.v25i1.57838.

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Diabetes mellitus (DM) is one of the most commonly diagnosed condition all over the world. Fish is a typical delicacy and one of the most nutritious foods available. Fresh fish bile, according to various indigenous healthcare professionals in Bangladesh, has anti-diabetic effects and its importance in the treatment or management of diabetes and cardiovascular illnesses has also been documented in few recent studies. The goal of this work was to test the hypoglycemic potential of Labeo rohita bile content in order to objectively validate this folklore claim. In this study, in-vivo investigation

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Rivera, Antonio, Elvia Becerra-Martinez, Yesenia Pacheco-Hernández, Gerardo Landeta-Cortés, and Nemesio Villa-Ruano. "Synergistic hypolipidemic and hypoglycemic effects of mixtures of Lactobacillus nagelii/betanin in a mouse model." Tropical Journal of Pharmaceutical Research 19, no. 6 (2020): 1269–76. http://dx.doi.org/10.4314/tjpr.v19i6.23.

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Purpose: To determine the nutraceutical effect of mixtures containing Lactobacillus nagelii/betanin on the carbohydrate and lipid metabolism of mice.Methods: Lactobacillus nagelii and betanin were isolated from the raw materials. These components were subsequently assessed for their anti-hyperglycemic and hypolipidemic activities, and administered individually or combined in normoglycemic and diabetic mice. These animals were subjected to a standard OGTT and given an atherogenic diet.Results: The combination of L. nagelii (2.0 × 109 CFU/mL) and betanin (30 mg/kg body weight) exerted a signific

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El-Noweihi, Amira, Nagla Elmelegy, Sally Bakar, and Shimaa El-Nasser. "HYPOGLYCEMIC AND HYPOLIPIDEMIC EFFECTS OF GINGER IMPROVE KIDNEY FUNCTION IN OBESE MALE RATS." Bulletin of Pharmaceutical Sciences. Assiut 42, no. 1 (2019): 19–29. http://dx.doi.org/10.21608/bfsa.2019.62260.

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Nweze, Chibuzo, Tayyibah Lay, Abdullahi Muhammad, and Abraham Ubhenin. "Hypoglycemic, Hepatoprotective and Hypolipidemic Effects of Pleurotus ostreatus in Alloxan-Induced Hyperglycemic Rats." Tropical Journal of Natural Product Research 1, no. 4 (2017): 163–67. http://dx.doi.org/10.26538/tjnpr/v1i4.5.

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Laaboudi, Wafa, Jamal Ghanam, Oumaima Ghoumari, Fatiha Sounni, Mohammed Merzouki, and Mohamed Benlemlih. "HYPOGLYCEMIC AND HYPOLIPIDEMIC EFFECTS OF PHENOLIC OLIVE TREE EXTRACT IN STREPTOZOTOCIN DIABETIC RATS." International Journal of Pharmacy and Pharmaceutical Sciences 8, no. 12 (2016): 287. http://dx.doi.org/10.22159/ijpps.2016v8i12.14077.

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<p><strong>Objective: </strong>The aim of the present study was to determine the effects of an olive tree extract with high polyphenols content on blood glucose level and other related parameters in streptozotocin-induced diabetic rats.<strong></strong></p><p><strong>Methods: </strong>Diabetes was induced in rats by intraperitoneal injection of streptozotocin (55 mg/kg bw). 72h after injection, rats with fasting blood glucose higher than 2 g/l were used for the experiments. Olive tree extract was administered for 28 d and blood glucose leve

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Hwang, Ji-Yeon, Jian Zhang, Min-Jung Kang, et al. "Hypoglycemic and hypolipidemic effects of Saururus chinensis Baill in streptozotocin-induced diabetic rats." Nutrition Research and Practice 1, no. 2 (2007): 100. http://dx.doi.org/10.4162/nrp.2007.1.2.100.

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Lee, Soo Jung, Gui Fang Zhang, and Nak Ju Sung. "Hypolipidemic and hypoglycemic effects ofOrostachys japonicusA. Berger extracts in streptozotocin-induced diabetic rats." Nutrition Research and Practice 5, no. 4 (2011): 301. http://dx.doi.org/10.4162/nrp.2011.5.4.301.

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Seo, Dongyeon, Naeun Kim, Ahyeong Jeon, et al. "Hypoglycemic and hypolipidemic effects of unsaponifiable matter from okra seed in diabetic rats." Nutrition Research and Practice 18, no. 3 (2024): 345. http://dx.doi.org/10.4162/nrp.2024.18.3.345.

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