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Journal articles on the topic 'Hypoglycemic Property'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Mubarak, Ayad S., and Tang Yiquen. "Hypoglycemic property of cocoa products: potential underlying mechanisms." International Current Pharmaceutical Journal 4, no. 2 (2015): 362–66. http://dx.doi.org/10.3329/icpj.v4i2.21485.

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Cocoa powder and chocolate is most abundant flavonoids-plant product. Type 2 diabetes mellitus (T2DM) is health and epidemically serious metabolic disorder. The treatment and moreover preventing of T2DM is therapeutic target worldwide. This review focuses on antidiabetic mechanisms of cocoa products. Particularly, intensifying insulin sensitivity, which is a superior pathway for chronic glucose level control, and increasing insulin release for acute glucose level control. Accordingly, the hypoglycemic effect results in elevate synthesis and bioavailability of nitric oxide (NO). Subsequently, i

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2

Dash, ArunKumar, BirendraKumar Pattanaik, SangeetaRani Behera, and AmiteshKumar Palo. "Study of antimicrobial property of some hypoglycemic drugs." Chronicles of Young Scientists 2, no. 4 (2011): 219. http://dx.doi.org/10.4103/2229-5186.93029.

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3

Wang, Hongyu, and Liang Li. "Comprehensive Evaluation of Probiotic Property, Hypoglycemic Ability and Antioxidant Activity of Lactic Acid Bacteria." Foods 11, no. 9 (2022): 1363. http://dx.doi.org/10.3390/foods11091363.

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Taking lactic acid bacteria is an important strategy to alleviate or prevent diabetes, but the candidate strains with good genetic stability and excellent functions still need to be supplemented. In this study, the hypoglycemic ability (α-amylase, α-glucosidase and dipeptidyl peptidase 4), probiotic property and antioxidant activity of lactic acid bacteria were comprehensively evaluated by a principal component analysis (PCA) and analytic hierarchy process (AHP). The results showed that Lactobacillus paracasei(L. paracasei) had a higher survival rate (82.78%) in gastric juice and good toleranc

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Mohapatra, L., S. K. Bhattamisra, R. C. Panigrahy, and S. Parida. "EVALUATION OF ANTIOXIDANT, HYPOGLYCAEMIC, ANTIDIABETIC AND ALPHA AMYLASE INHIBITING ACTIVITIES OF SARGASSUM WIGHTII COLLECTED FROM THE EAST COAST OF INDIA." INDIAN DRUGS 55, no. 01 (2018): 61–69. http://dx.doi.org/10.53879/id.55.01.10988.

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This study evaluated the antioxidant, hypoglycemic, antidiabetic and alpha amylase inhibiting activities of Sargassum wightii. Antioxidant activity of ethyl acetate and methanol extracts of this seaweed was evaluated and extract having promising antioxidant activity was further studied for hypoglycaemic and antidiabetic activity in normal and alloxan induced diabetic mice, respectively, at 100 and 200mg/ kg after toxicity evaluation. Ethyl acetate extract of S. wightii (EAS) has shown promising antioxidant, hypoglycemic and antidiabetic activity. Total phenol content for EAS was 250.09 ± 4.41m

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Dasgupta, Tumpa, Amlan Ganguly, Muhammad Asaduzzaman, and Nazmul Qais. "Evaluation of Anti-microbial, Hypoglycemic and Anti-diarrheal activities of Setaria italica Seeds." Dhaka University Journal of Pharmaceutical Sciences 15, no. 1 (2016): 31–35. http://dx.doi.org/10.3329/dujps.v15i1.29190.

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The ethanolic crude extract of Setaria italica seeds (Poaceae) was investigated for its possible anti-microbial, hypoglycemic and anti-diarrheal activities. Anti-microbial activity was evaluated by disc diffusion method while the hypoglycemic and anti-diarrheal properties were determined by oral glucose tolerance test and castor oil induced diarrheal method, respectively in Albino mice. The ethanolic extract and its different fractions of S. italica have shown good antimicrobial activity against gram negative bacteria having zone of inhibition 9-13 mm (ciprofloxacin: 40- 41 mm). In evaluation

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Mamadou, Dosso, Coulibaly Adama, Coulibaly Ousmane, Soro Doudjo, and N'guessan J. David. "Potential anti-diabetic property of the aqueous extract of the leaves of Saba senegalensis Pichon (apocynaceae) in mice." International Journal of Pharmacology and Toxicology 8, no. 1 (2020): 65. http://dx.doi.org/10.14419/ijpt.v8i1.30635.

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This study made it possible to demonstrate that Saba senegalensis has hypoglycemic and anti-hyperglyvemic effects in mice. The aqueous extract of Saba senegalensis from 75 to 250 mg / Kg bw causes a dose-dependent hypoglycemia ranging from 4.84 to 34.62% (p <0.01-0.05), in normoglycemic mice, 60 minutes after treatment. The Glucose-Induced Hyperglycemia Orally (OPGH) test showed that in the presence of Saba senegalensis aqueous extract at a concentration between 75 and 250mg/Kg bw, the glucose-induced hyperglycemic peak (3g/Kg bw) is reduced from 26.49 to 71.77% (p < 0.01-0.05), 30 minut

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Sarkhail, Parisa, and Peyman Rahmani. "Hypoglycemic Property of Satureja khuzestanica in Human Still in Doubt." International Journal of Pharmacology 7, no. 7 (2011): 745–46. http://dx.doi.org/10.3923/ijp.2011.745.746.

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8

Moqbel, Fahmi S., and Prakash R. Naik. "Effect of different fractions of Hibiscus rosa sinensis leaf extract on islets of Langerhans and antioxidant activity in non-obese diabetic (NOD) mouse." Journal of Applied and Natural Science 3, no. 2 (2011): 206–10. http://dx.doi.org/10.31018/jans.v3i2.180.

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The present investigation was undertaken to study the effect of Hibiscus rosa sinensis leaf extract fractions on islets of Langerhans, total antioxidant activity in non-obese diabetic (NOD) mouse. Two sets of experiments were conducted. First experiment was designed to test the hypoglycemic properties of different isolated fractions. Five fractions were screened for hypoglycemic property. Fractions F3, F4 and F5 showed hypoglycemic in NOD mice. Second set of experiment was conducted to assess the effects of above fractions on the diameter of islets of Langerhans and on the â-cells number and t

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9

LUYEN, NGUYEN THI, NGUYEN HAI DANG, PHUNG THI XUAN BINH, NGUYEN THI HAI, and NGUYEN TIEN DAT. "Hypoglycemic property of triterpenoid saponin PFS isolated from Polyscias fruticosa leaves." Anais da Academia Brasileira de Ciências 90, no. 3 (2018): 2881–86. http://dx.doi.org/10.1590/0001-3765201820170945.

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10

Okpanachi, Gideon, Avosuahi Oyi, Hassan Musa, A. Abdulsamad, Muhammad Sani, and Jamilu Ya’u. "Phytochemical Screening and Hypoglycemic Property of Globimetula braunii (Loranthaceae) Leaf Extracts." Journal of Pharmaceutical Research International 22, no. 1 (2018): 1–11. http://dx.doi.org/10.9734/jpri/2018/39870.

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11

Sunmonu, Taofik O., and Anthony J. Afolayan. "Evaluation of Antidiabetic Activity and Associated Toxicity ofArtemisia afraAqueous Extract in Wistar Rats." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–8. http://dx.doi.org/10.1155/2013/929074.

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Artemisia afraJacq. ex Willd. is a widely used medicinal plant in South Africa for the treatment of diabetes. This study aimed to evaluate the hypoglycemic activity and possible toxicity effect of aqueous leaf extract of the herb administered at different dosages for 15 days in streptozotocin-induced diabetic rats. Administration of the extract at 50, 100, and 200 mg/kg body weight significantly (P<0.05) increased body weight, decreased blood glucose levels, increased glucose tolerance, and improved imbalance in lipid metabolism in diabetic rats. These are indications of antidiabetic proper

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12

Kollind, M., U. Adamson, and P. E. Lins. "Somatostatin reduces posthypoglycemic insulin resistance in insulin-dependent diabetes mellitus." Acta Endocrinologica 118, no. 2 (1988): 173–78. http://dx.doi.org/10.1530/acta.0.1180173.

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Abstract. In order to study whether somatostatin reduces posthypoglycemic insulin resistance, hypoglycemia was induced between 7.00 and 8.00 h by an iv infusion of insulin with and without somatostatin (250 μg/h) in 6 male patients with insulin-dependent diabetes mellitus (IDDM). Exogenous glucagon was infused to substitute for the suppression of its endogenous release (1.0-1.5 ng·kg−1·min−1). Insulin resistance was assessed by a somatostatin-insulin-infusion test (SIGIT) between 11.00 and 15.00 h. In the study without hypoglycemia, blood glucose was kept close to 6 mmol/l from 8.00 h until st

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13

Jin, Ming, Ming-hua Shen, Mei-hua Jin, Ai-hua Jin, Xue-zhe Yin, and Ji-shu Quan. "Hypoglycemic property of soy isoflavones from hypocotyl in Goto-Kakizaki diabetic rats." Journal of Clinical Biochemistry and Nutrition 62, no. 2 (2018): 148–54. http://dx.doi.org/10.3164/jcbn.17-68.

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14

Borikar, Sachin P., Nilesh G. Kallewar, Debarshi Kar Mahapatra, et al. "Decoction of Andrographis paniculata whole plant and Gymnema sylvestre leaves demonstrated noteworthy hypoglycemic activity in Sprague Dawley rat." Journal of Phytopharmacology 7, no. 1 (2018): 84–87. http://dx.doi.org/10.31254/phyto.2018.7117.

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Mother Nature is an elite source for the exploration of leads with good hypoglycemic potential. Progressing in the direction of research, two well-known plants from the Indian subcontinent; A. paniculata (Family: Acanthaceae) and G. sylvestre (Family: Apocynaceae) were chosen and evaluated for their hypoglycemic property in alloxan induced diabetic rat model using metformin hydrochloride as the standard drug. In the current investigation, whole plant decoction of A. paniculata and decoction of G. sylvestre leaves were utilized. The research specified preliminary phytochemical investigations wh

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15

Begum, H., F. Parveen, MJ Iqbal, and SN Islam. "Hypoglycemic Property of the Ethanolic Extract of Cinnamon on Alloxan Induced Diabetic Mice." Bangladesh Medical Journal 41, no. 2 (2014): 13–16. http://dx.doi.org/10.3329/bmj.v41i2.18794.

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This study aimed to investigate the effect of ethanolic extract of cinnamon on hyperglycemic mice. Cinnamon extract was administered at 150mg/kg and 200mg/kg body weight in alloxan induced hyperglycemic mice and the glucose lowering effect was compared to a standard oral anti diabetic drug- glibenclamide for 28 days. The fasting glucose level was measured in serum of normal and alloxan induced hyperglycemic mice. Diabetic mice exhibited an increase in the levels of glucose. It was found that blood glucose concentration was significantly decreased in a dose-dependent manner (p<0.001) with th

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16

Shang, Hongmei, Jiangchao Zhao, Yang Guo, Hexiang Zhang, Mengying Duan, and Hongxin Wu. "Extraction, purification, emulsifying property, hypoglycemic activity, and antioxidant activity of polysaccharides from comfrey." Industrial Crops and Products 146 (April 2020): 112183. http://dx.doi.org/10.1016/j.indcrop.2020.112183.

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17

Wang, Jing, Weihua Jin, Wenjing Zhang, Yun Hou, Hong Zhang, and Quanbin Zhang. "Hypoglycemic property of acidic polysaccharide extracted from Saccharina japonica and its potential mechanism." Carbohydrate Polymers 95, no. 1 (2013): 143–47. http://dx.doi.org/10.1016/j.carbpol.2013.02.076.

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18

Cajuday, Lilibeth A., and Edna A. Amparado. "Hypoglycemic property of Telosma procumbens (Blanco) Merr. (Apocynaceae) in normal and alloxan-induced diabetic juvenile mice (Mus musculus)." Journal of Phytopharmacology 3, no. 2 (2014): 113–17. http://dx.doi.org/10.31254/phyto.2014.3206.

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The incidence of diabetes is alarmingly fast in both developed and developing countries. In Third World countries, medicinal plants have always played a significant role in the maintenance of health and management of diseases. In the Philippines, there are many plants with reported antidiabetic property, but are not scientifically tested yet including Telosma procumbens (Blanco) Merr. Using male mice as model organism, ethanolic leaf extract of the plant was tested for hypoglycemic activity in both normoglycemic and alloxan-induced diabetic mice. Results obtained proved the blood glucose reduc

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19

Sharma, Himanshi, Aakar Singh, Shivanghi Srivastava, Shivanshu Pandey, and Shivom Verma. "Assessment of Anti-Diabetic Property of Cassia occidentalis Seed Extract in Wistar Rats." International Journal of Pharmaceutical Sciences and Medicine 9, no. 6 (2024): 85–103. http://dx.doi.org/10.47760/ijpsm.2024.v09i06.009.

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The study investigates the anti-diabetic effects of ethanol extracts from Cassia occidentalis seeds in normal and alloxan-induced diabetic rats. Cassia occidentalis, known for its anti-hepatotoxic and antibacterial properties, has been claimed to have hypoglycemic effects. Acute toxicity studies in Wistar rats revealed reduced food and beverage intake and body weight with the ethanol extract. In diabetic rats, the extract significantly reduced blood glucose levels and promoted regeneration of necrosed kidney and pancreas tissues. Histopathological analysis suggested potential beta cell regener

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20

Rachael, Omodara, Tolani, Awoyinka, Olayinka Anthony, and Omojokun, Ayomide Olubunmi. "Comparative Effects of Fermented and Unfermented Parkia biglobosa Bean Seeds in Diabetic Induced Experimental Rats." Microbiology Research Journal International 34, no. 2 (2024): 44–52. http://dx.doi.org/10.9734/mrji/2024/v34i21431.

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Aims: The present work investigates the hypoglycemic effect of fermented seeds of Parkia biglobosa (PB, African locust beans) in alloxan-induced diabetic rats. Its effect was compared with that of unfermented Parkia biglobosa. Methodology: In order to assess the hypoglycemic effects of the fermented seeds on experimental animals, fasting blood sugar (FBS), total cholesterol, triglycerides, high-density lipoprotein (HDL), and low-density lipoprotein (LDL) were determined. The microbiota analysis of the fecal sample was also determined. Result: Alloxan administered to the rats signif

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21

Xu, Weidong, Jiayao Li, Weipeng Qi, and Ye Peng. "Hypoglycemic Effect of Vitexin in C57BL/6J Mice and HepG2 Models." Journal of Food Quality 2021 (March 10, 2021): 1–7. http://dx.doi.org/10.1155/2021/5535476.

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Apigenin-8-C-glucoside (vitexin), a natural phytochemical contained in hawthorn, has been reported to have versatile beneficial bioactivities, such as antioxidation, anticancer property, and adipogenesis inhibition. The present research aimed to determine the influence of vitexin on insulin resistance elicited by HFD in mice and HepG2 cells. Vitexin markedly alleviated body weight gain and improved glucose and insulin intolerance induced by HFD. Vitexin partially normalized blood glucose, cholesterol, TNF-α, and hepatic lipid content. Moreover, vitexin recovered the reduced glucose uptake indu

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22

Peng, Fei, Xin Ren, Bin Du, Linan Chen, Zuoqing Yu, and Yuedong Yang. "Structure, Physicochemical Property, and Functional Activity of Dietary Fiber Obtained from Pear Fruit Pomace (Pyrus ussuriensis Maxim) via Different Extraction Methods." Foods 11, no. 14 (2022): 2161. http://dx.doi.org/10.3390/foods11142161.

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In this study, soluble dietary fiber (SDF) and insoluble dietary fiber (IDF) were extracted from Pyrus ussuriensis Maxim pomace via three methods including enzymic extraction (EE), microwave-assisted enzymatic extraction (MEE), and three-phase partitioning (TPP). The effects of different extraction methods on the structure, physicochemical property, and functional activity of the extracted dietary fiber were evaluated. The results showed that different extraction methods had significant effects on the extraction yield, molecular weight distribution, thermal stability, antioxidant activity, and

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23

Bothiraj K V, Murugan, and Vanitha V. "Green coffee bean seed and their role in antioxidant–A review." International Journal of Research in Pharmaceutical Sciences 11, no. 1 (2020): 233–40. http://dx.doi.org/10.26452/ijrps.v11i1.1812.

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All around the world, Coffee place an important position in the beverages. It contains phenolic acid as well as polyphenols. It has the property of antioxidant; mood enhances mood, and also increases alertness, reduces weight, efficiency against hypertension, and antitumor property because of its polyphenols and phenolic constituents. Chlorogenic acids (CGA) are the main components found in the fraction of phenols from green coffee beans. CGA has several therapeutic properties, which include antioxidant activities and also has hepatoprotective, hypoglycemic, and antiviral properties. Several e

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Agarwal, Rakesh, Yogi Amrit Raj, and Dinesh Kumar. "Hypoglycemic potential of Momordica charantia Linn in Streptozotocin induced diabetic Albino mice." Environment Conservation Journal 11, no. 3 (2010): 1–5. http://dx.doi.org/10.36953/ecj.2010.110301.

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In order to check hypoglycemic property of Momordica charantia, experiments were conducted in streptozotocin induced diabetic albino mice. The LD50 of STZ was seen to be 650 mg/kg bw. Significant reduction in blood glucose level was seen within 24 hours after administration of ethanolic extract of MC. On administration of subsequent doses of ethanolic extract, significant decrease has also been seen in serum glucose level, creatinine, ALT, AST, AP of STZ induced albino mice. Thus one or other part of MC can be used in lowering down blood glucose level.

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Begum, Parveen, Fatema Tabassum, Md Abdullah Al Noman, Monira Ahsan, and Sheikh Nazrul Islam. "HYPOGLYCEMIC PROPERTY OF ETHNIC VEGETABLES CONSUMED BY THE TRIBAL PEOPLE OF CHITTAGONG HILL TRACTS." International Research Journal of Pharmacy 8, no. 10 (2017): 25–28. http://dx.doi.org/10.7897/2230-8407.0810177.

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Khulood S., Salim. "Hypoglycemic Property of Ginger and Green Tea and their Possible Mechanisms in Diabetes Mellitus." Open Conference Proceedings Journal 5, no. 1 (2014): 13–19. http://dx.doi.org/10.2174/2210289201405010013.

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27

Devkota, HP, A. Adhikari-Devkota, S. Yahara, and P. Basnet. "Anti-oxidative Activity of Nepalese Traditional Anti-diabetic Medicines." Nepal Journal of Science and Technology 14, no. 2 (2014): 151–54. http://dx.doi.org/10.3126/njst.v14i2.10429.

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Chronic overproduction of free radicals in human body has a role in numerous disease states including diabetes. Proper use of antioxidants may help in the prevention and/or treatment of diabetes. For the management of diabetes, a combination of herbal drugs is being practiced traditionally in Nepal. These herbal medicines might have a good correlation to anti-oxidative properties. Anti-oxidative property was evaluated with the methanolic extracts of nineteen common traditional anti-diabetic medicines by 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging method. Among the evaluated herbal

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Kurian, Gino A. "Hypoglycemic effect of poly-herbal combination in streptozotocin-induced diabetic rats." Bangladesh Journal of Pharmacology 11, no. 2 (2016): 364. http://dx.doi.org/10.3329/bjp.v11i2.24855.

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<p class="Abstract">The present study evaluates the combinatorial effect of a poly-herbal combination with multiple therapeutic effects as a hypoglycemic and hypolipidemic agent. Herbal combination of <em>Salacia oblonga, Tinospora cordifolia, Emblica officinalis, Curcuma longa</em> and <em>Gymnema sylvestre</em> was prepared and administered to streptozotocin (55 mg/kg, i.p.)-induced diabetic rats, at a dose of 100 mg/kg, for four weeks. The poly-herbal combination significantly elevated the plasma insulin (90%) and reduced serum glucose (42%), cholesterol (49%),

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Chandiran, Irisappan Sarath, Korlakunta Narasimha Jayaveera, and Karimulla Shaik. "Antioxidant property of Grewia serrulata DC and its hypoglycemic effect on normal and hyperglycemic rats." Journal of Pharmacy Research 6, no. 8 (2013): 813–17. http://dx.doi.org/10.1016/j.jopr.2013.08.004.

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30

Chin, Yao Xian, Xin Chen, Wan Xiu Cao, et al. "Characterization of seaweed hypoglycemic property with integration of virtual screening for identification of bioactive compounds." Journal of Functional Foods 64 (January 2020): 103656. http://dx.doi.org/10.1016/j.jff.2019.103656.

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Hussain, Mazhar, Muhammad Amir Rafique, Abdul Qudoos Arain, Shoaib Akhtar, Muhammad Bilal Ghafoor, and Lubna Akhtar. "To compare the efficacy and safety profile of sitagliptin and glimipiride in type 2 diabetic patients." Professional Medical Journal 27, no. 05 (2020): 895–901. http://dx.doi.org/10.29309/tpmj/2020.27.05.3401.

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Objectives: To compare the efficacy and safety profile of sitagliptin vs. glimepiride in type 2 diabetic patients. Study Design: Comparative study. Setting: At Islam Central Hospital, Sialkot at its Medical outdoor unit. Period: 16 week from September to December 2018. Materials & Methods: In which Type 2 diabetic patients (n=220) were randomly placed into interventional groups to prescribed either sitagliptin or glimepiride for an interval of 16 weeks. A blood sugar level was maintained by dose titration in both groups. The main end point was change in FBG & HbA1C while additional end

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Ampawong, Sumate, Duangnate Isarangkul, and Pornanong Aramwit. "Sericin ameliorated dysmorphic mitochondria in high-cholesterol diet/streptozotocin rat by antioxidative property." Experimental Biology and Medicine 242, no. 4 (2016): 411–21. http://dx.doi.org/10.1177/1535370216681553.

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Sericin has been implicated in lower cholesterolemic effect due to its properties with several mechanisms. Mitochondria are one of the most important targets to be affected in high blood cholesterol and glucose conditions. The protective role of sericin on mitochondria remains doubtful. To examine this role, electron microscopic, histopathologic, immunohistochemical, and biochemical studies were performed in a high-cholesterol diet/streptozotocin rat model. The results demonstrated that sericin reduced blood cholesterol without hypoglycemic effect. Sericin alleviated dysmorphic mitochondria in

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Parisi, Ortensia Ilaria, Mariarosa Ruffo, Fabio Amone, et al. "PDO Rotonda’s Red Eggplant Extract: In vitro Determination of Biological Properties and Minerals Bioaccessibility." Current Nutrition & Food Science 16, no. 1 (2020): 65–74. http://dx.doi.org/10.2174/1573401314666180622110952.

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Background: The Rotonda’s Red Eggplant belongs to the family of Solanum aethiopicum and it is cultivated in a specific area of Potenza (Basilicata, South of Italy) including villages of Rotonda, Viggianello, Castelluccio Superiore and Castelluccio Inferiore. The Red Eggplant cultivated in this area has gained the PDO, “Protected Designation of Origin”. Objective: The aim of this research was to evaluate the use of PDO Rotonda’s Red Eggplant extract as a possible nutraceutical supplement. The antioxidant, antihypertensive, hypoglycemic, and hypolipidemic properties were in vitro evaluated. Meth

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Chandran, Rahul, Saikumar Sathyanarayanan, Murugan Rajan, Muniyandi Kasipandi, and Thangaraj Parimelazhagan. "Anti-oxidant, hypoglycemic and anti-hyperglycemic properties of Syzygium calophyllifolium." Bangladesh Journal of Pharmacology 10, no. 3 (2015): 672. http://dx.doi.org/10.3329/bjp.v10i3.23361.

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<p class="Abstract">The article discusses anti-oxidant oral glucose tolerance and anti-hyperglycemic potentials of <em>Syzygium calophyllifolium</em>. Extracts from successive solvent extraction were tested for the total phenolic, tannin, flavonoid content and free radical scavenging property using DPPH, ABTS<sup>+</sup>, phosphomolyb-denum, FRAP, superoxide and metal chelating assays. Ethyl acetate extract of bark responded well against DPPH (IC<sub>50</sub> 4.13), ABTS<sup>+</sup> (36832.29 µM TE/ g extract),phosphomolybdenum (100.4 g AAE

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Moukette, Bruno Moukette, Vicky Jocelyne Ama Moor, Cacral Prosper Biapa Nya, et al. "Antioxidant and Synergistic Antidiabetic Activities of a Three-Plant Preparation Used in Cameroon Folk Medicine." International Scholarly Research Notices 2017 (April 26, 2017): 1–7. http://dx.doi.org/10.1155/2017/9501675.

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Introduction. Several plant preparations like a mixture of aqueous extracts of Spilanthes africana; Portulaca oleracea; and Sida rhombifolia are currently utilized in Foumban (West Cameroon) to manage diabetes. The aim of this study is to investigate the antidiabetic property of the aqueous mixture of three plant extracts (1 : 1 : 1) on streptozotocin induced diabetes rats. Methods. Diabetes was induced to rats by intraperitoneal (i.p.) injection of streptozotocin (STZ) at a dose of 50 mg/kg b.w. The diabetic rats received different dosages of the mixture of extracts for 21 days and glibenclam

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Chaurasia, J. K., and Yamini B. Tripathi. "Chemical characterization of various fractions of leaves ofCinnamomum tamalaLinn toward their antioxidant, hypoglycemic, and anti-inflammatory property." Immunopharmacology and Immunotoxicology 33, no. 3 (2010): 466–72. http://dx.doi.org/10.3109/08923973.2010.538850.

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Chan, Eric Wei Chiang, Siu Kuin Wong, and Hung Tuck Chan. "Volkameria inermis: An overview of its chemical constituents and pharmacological properties, notably the amelioration of motor tics." Journal of Herbmed Pharmacology 12, no. 2 (2023): 176–86. http://dx.doi.org/10.34172/jhp.2023.18.

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This overview on Volkameria inermis (Lamiaceae) is the first in updating information on the chemical constituents and pharmacological properties of the species, notably on its unique ability in ameliorating motor tics. The information was procured from Google, Google Scholar, PubMed, PubMed Central, Science Direct, J-Stage, and PubChem. Previously named Clerodendrum inerme (Verbenaceae), V. inermis is a scrambling or scandent coastal shrub in the tropics and sub-tropics. From different parts of the plant, compounds such as flavonoids, diterpenes/diterpenoids, sterols, triterpenes/triterpenoids

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Hypoglycemic, Effect of Methanol Extract of Carica Papaya (Pawpaw) Leaves in Alloxan-Induced Diabetic Rats, O. ALAEBO Prince, E. ORIAKU Chinwe, et al. "Hypoglycemic Effect of Methanol Extract of Carica Papaya (Pawpaw) Leaves in Alloxan-Induced Diabetic Rats." International Journal of Innovative Science and Research Technology 7, no. 1 (2022): 627–31. https://doi.org/10.5281/zenodo.5995940.

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This experiment evaluatedthe hypoglycemic effect of methanol extract of Carica papaya leaves in alloxan-induced diabetic rats. Forty (40) male albino rats were grouped into eight: Group A (normal control), Group B (positive control) were induced and treated with glibenclamide, group C (negative control) were induced and not treated, group Dwas induced and treated with Carica papaya leave extract at doses of 200, group E induced and treated with Carica papaya leave extract at doses of 400, group F induced and treated with Carica papaya leave extract at doses of 600, group G induced and treated

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Hanley, James F., Darin D. Willardsen, and Robert Biberdorf. "Profound Hypoglycemia in a Mail-Order Pharmacy Customer as a Result of a Dispensing Error." Hospital Pharmacy 37, no. 7 (2002): 734–36. http://dx.doi.org/10.1177/001857870203700714.

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Accidental hypoglycemia is most commonly associated with the inadvertent ingestion of oral hypoglycemic drugs, and profound hypoglycemia can result in significant morbidity and mortality. Dispensing errors involving sulfonylureas are usually cited as the cause, and these errors have historically been related to sound-alike compounds or proximity errors. We present the case of a patient who received sulfonylureas meant for a different patient through the mail and simply complied with the instructions on the medication bottle, with the result of severe hypoglycemia. This case demonstrates the ne

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Kamisah, Yusof, Faizah Othman, Hj Mohd Saad Qodriyah, and Kamsiah Jaarin. "Parkia speciosaHassk.: A Potential Phytomedicine." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/709028.

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Parkia speciosaHassk., or stink bean, is a plant indigenous to Southeast Asia. It is consumed either raw or cooked. It has been used in folk medicine to treat diabetes, hypertension, and kidney problems. It contains minerals and vitamins. It displays many beneficial properties. Its extracts from the empty pods and seeds have a high content of total polyphenol, phytosterol, and flavonoids. It demonstrates a good antioxidant activity. Its hypoglycemic effect is reported to be attributable to the presence ofβ-sitosterol, stigmasterol, and stigmast-4-en-3-one. The cyclic polysulfide compounds exhi

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Gupta, Saran Kumar, Ashis Kumar Nanda, Raja Ghosh, and Palash Mandal. "ELICITATION OF TRIGONELLINE, A HYPOGLYCEMIC AGENT IN FENUGREEK SPROUTS BY CALCIUM AND NITRIC OXIDE PRIMING." Asian Journal of Pharmaceutical and Clinical Research 10, no. 5 (2017): 120. http://dx.doi.org/10.22159/ajpcr.2017.v10i5.16910.

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Objective: This work was performed to evaluate the effect of priming with exogenous sources of calcium ion and nitric oxide on the antidiabeticactivity and the alkaloid contents of fenugreek sprouts along with isolation and identification of trigonelline, a bioactive alkaloid responsible for hypoglycemic property of fenugreek.Methods: The fenugreek seeds were pre-treated with calcium chloride (CC), lanthanum chloride (LC) a calcium channel blocker; ethylene glycol-bis (2-aminoethylether) -N, N, N´, N tetra acetic acid (EG) a calcium chelator; sodium nitroprusside (SNP) and 2-(4-carboxyphenyl)

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Rayam, Sriharsha, B. L. Kudagi, Umer Sufyan M., Madhavulu Buchineni, and Rama Mohan Pathapati. "Assessment of Morus alba (Mulberry) leaves extract for anti-convulsant property in rats." International Journal of Basic & Clinical Pharmacology 8, no. 3 (2019): 520. http://dx.doi.org/10.18203/2319-2003.ijbcp20190658.

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Background: The mulberry tree, a plant of the family Moraceae and the genus Morus, has been widely cultivated to feed silkworms. Various parts of Morus alba linn used as an Anti-inflammatory, hypoglycemic, cardioprotective, hepatoprotective, free radical scavenging activity and neuroprotective agent. The plant contains flavonoids, moranoline, albanol, morusin coumarine, and stilbene, which have. In this study, anticonvulsant property of Morus alba leaves extract (MAE) was evaluated by using MES and PTZ induced convulsion in rats.Methods: Effects of MAE were evaluated in experimental models of

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Melino, Leo, and Papajani. "Natural Hydrogen Sulfide Donors from Allium sp. as a Nutraceutical Approach in Type 2 Diabetes Prevention and Therapy." Nutrients 11, no. 7 (2019): 1581. http://dx.doi.org/10.3390/nu11071581.

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Type 2 diabetes mellitus (DM) is a socially relevant chronic disease with high prevalence worldwide. DM may lead to several vascular, macrovascular, and microvascular complications (cerebrovascular, coronary artery, and peripheral arterial diseases, retinopathy, neuropathy, and nephropathy), often accelerating the progression of atherosclerosis. Dietary therapy is generally considered to be the first step in the treatment of diabetic patients. Among the current therapeutic options, such as insulin therapy and hypoglycemic drugs, in recent years, attention has been shifting to the effects and p

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Emeka, Emordi Jonathan, Agbaje Esther Oluwatoyin, Oreagba Ibrahim Adekunle, and Iribhogbe Osede Ignis. "Preliminary phytochemical screening and evaluation of hypoglycemic properties of the root extract of Uveria chamae." Bangladesh Journal of Pharmacology 10, no. 2 (2015): 326. http://dx.doi.org/10.3329/bjp.v10i2.22287.

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<p>The purpose of this study is to evaluate the hypoglycaemic properties and preliminary phytochemical screening of <em>Uveria chamae</em>. The hypoglycaemic properties of <em>Uveria chamae</em> was assessed on normoglycaemic rat that received single dose of the extract at 250 and 500 mg/kg body weight and blood glucose levels estimated at 2, 4, and 6 hours (single dose study). The hypoglycaemic property of the extract was also evaluated in normoglycemic rats by oral glucose tolerance test. Phytochemical screening of the extract for the presence of secondary metab

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Begum, Anjuman Ara, Md Mosiul Haque, Mahfuzul Islam, and Sukalyan Kumar Kundu. "Evaluation of Antioxidant Activity and Cytotoxic Property of Methanolic Extract of Flemingia macrophylla (Willd.)." Bangladesh Pharmaceutical Journal 16, no. 2 (2015): 159–63. http://dx.doi.org/10.3329/bpj.v16i2.22298.

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Flemingia macrophylla locally known as Charchara in Bangladesh is a medicinal herb. Being a member of the Fabaceae family it claims a number of medicinal uses including hypoglycemic activity, neuroprotective effect and gynecological remedies. Methanolic extract of F. macrophylla was investigated to evaluate its antioxidant and general toxic properties in this study. Antioxidant potential was evaluated using total antioxidant capacity, total phenol contents, total flavonoid contents and DPPH (1,1-diphenyl-2-picrylhydrazyl) assays. Both leaf and stem extracts of F. macrophylla were found to po

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Arumugam, Balakrishnan, Arunambiga Subramaniam, and Praveena Alagaraj. "Stevia as a Natural Sweetener: A Review." Cardiovascular & Hematological Agents in Medicinal Chemistry 18, no. 2 (2020): 94–103. http://dx.doi.org/10.2174/1871525718666200207105436.

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: Stevia rebaudiana of the Asteraceae family is a perennial shrub. It is a sweetener herb also known as sweet weed, sweet leaf, sweet herbs and honey leaf, native to Argentina, Brazil and Paraguay. The leaves of stevia are sweeter than sucrose with zero calories. Steviol, a diterpenoid glycoside derivative identified from this plant, is sweeter than sucrose and is safe when used as a sweetening agent. Diabetic and obese people with hyperglycemia who are in a condition to follow a strict diet can use stevioside as an alternative sweetener. In addition to its hypoglycemic property, the plant als

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Rath, Deepankar, Gurudutta Pattnaik, and Biswakanth Kar. "An Overview on Ethnopharmacology of Different Medicinal Plants of Odisha State of India in the Management of Diabetes Mellitus." Asian Journal of Chemistry 33, no. 11 (2021): 2589–98. http://dx.doi.org/10.14233/ajchem.2021.23389.

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Diabetes mellitus, commonly known as diabetes, is a group of metabolic disorder associated with elevated blood glucose level. World health organization recommended the traditional and herbal remedies for the diabetic management. The application of herbal remedies is extremely increased worldwide in the last three decades. Most of the synthetic drugs were discovered from the plant source out of different regions of the world to meet the demand. Several medicinal plants like Gymnema sylvestre, Pterocarpus marsupium, Catharanthus roseus, Trigonella foenum, Annona squamosa, Aegle marmelos, Withani

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Wen, Kun, Qiyun Zhang, Jing Xie, et al. "Effect of Mono- and Polysaccharide on the Structure and Property of Soy Protein Isolate during Maillard Reaction." Foods 13, no. 17 (2024): 2832. http://dx.doi.org/10.3390/foods13172832.

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As a protein extracted from soybeans, soy protein isolate (SPI) may undergo the Maillard reaction (MR) with co-existing saccharides during the processing of soy-containing foods, potentially altering its structural and functional properties. This work aimed to investigate the effect of mono- and polysaccharides on the structure and functional properties of SPI during MR. The study found that compared to oat β-glucan, the reaction rate between SPI and D-galactose was faster, leading to a higher degree of glycosylation in the SPI–galactose conjugate. D-galactose and oat β-glucan showed different

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Du, Bin, Maninder Meenu, Hongzhi Liu та Baojun Xu. "A Concise Review on the Molecular Structure and Function Relationship of β-Glucan". International Journal of Molecular Sciences 20, № 16 (2019): 4032. http://dx.doi.org/10.3390/ijms20164032.

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β-glucan is a non-starch soluble polysaccharide widely present in yeast, mushrooms, bacteria, algae, barley, and oat. β-Glucan is regarded as a functional food ingredient due to its various health benefits. The high molecular weight (Mw) and high viscosity of β-glucan are responsible for its hypocholesterolemic and hypoglycemic properties. Thus, β-glucan is also used in the food industry for the production of functional food products. The inherent gel-forming property and high viscosity of β-glucan lead to the production of low-fat foods with improved textural properties. Various studies have

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Suman, Rajesh Kumar, Ipseeta Ray Mohanty, Manjusha K. Borde, et al. "Evaluation of antidiabetic efficacy of Murraya koenigii on Streptozotocin induced diabetes in experimental rats." International Journal of Basic & Clinical Pharmacology 8, no. 8 (2019): 1906. http://dx.doi.org/10.18203/2319-2003.ijbcp20193200.

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Background: The medicinal plant Murraya koenigii shown to have a wide variety of pharmacological activities (hypoglycemic and hypolipidemic). Objective of this study is the present study was designed to evaluate Antidiabetic and Hypolipidemic property of Murraya koenigii in experimentally induced diabetes in rats.Methods: Experimental diabetes was produced with single dose of Streptozotocin (STZ): 45 mg/kg IP. The rats were randomly allocated in various groups for 37 days. After the confirmation of diabetes on 7th day (>200 mg/dl), hydroalcoholic extract of Murraya koenigii (500 mg/kg) was

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