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Relevant bibliographies by topics / Hypoglycin

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Journal articles
Dissertations / Theses
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Academic literature on the topic 'Hypoglycin'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "Hypoglycin"

1

Van Hoof, F., L. Hue, J. Vamecq, and H. S. Sherratt. "Protection of rats by clofibrate against the hypoglycaemic and toxic effects of hypoglycin and pent-4-enoate. An ultrastructural and biochemical study." Biochemical Journal 229, no. 2 (1985): 387–97. http://dx.doi.org/10.1042/bj2290387.

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An ultrastructural and biochemical study of the toxic and hypoglycaemic effects of hypoglycin and pent-4-enoate was made on the livers of normal and clofibrate-fed rats. Injection of hypoglycin to rats doubles (from 22% to 44%) the volume fraction of mitochondria and decreases (from 1.05% to 0.26%) the volume fraction of peroxisomes in hepatocytes. The fast-acting toxin pent-4-enoate causes few ultrastructural changes except for the accumulation of lipids. In male adult rats fed with 0.5% clofibrate in their diet for 1-2 months, the volume fraction occupied by peroxisomes and mitochondria in h

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2

Hue, L., and H. S. Sherratt. "Inhibition of gluconeogenesis by hypoglycin in the rat. Evidence for inhibition of glucose-6-phosphatase in vivo." Biochemical Journal 240, no. 3 (1986): 765–69. http://dx.doi.org/10.1042/bj2400765.

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Treatment of rats with hypoglycaemic doses of hypoglycin has been shown to abolish the relative detritiation of [2-3H,U-14C]glucose [Osmundsen, Billington, Taylor & Sherratt (1978) Biochem. J. 170, 337-342], indicating that both the Cori and the glucose/glucose 6-phosphate cycles were inhibited in vivo. This inhibition was confirmed and, in addition, it was shown that the conversion in vivo of both [14C]lactate and [14C]fructose into glucose was decreased after hypoglycin treatment. These results suggest that hypoglycin poisoning results in the inhibition in vivo of glucose-6-phosphatase a

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Veitch, R. K., H. S. A. Sherratt, and K. Bartlett. "Organic aciduria in rats made resistant to hypoglycin toxicity by pretreatment with clofibrate." Biochemical Journal 246, no. 3 (1987): 775–78. http://dx.doi.org/10.1042/bj2460775.

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1. The lethal, hypoglycaemic and hypothermic effects of hypoglycin in fasted rats are prevented if the rats had been fed on a diet containing clofibrate (0.5% w/w). 2. Injection of hypoglycin into fasted rats maintained on a standard diet caused severe prostration, hypothermia and a massive dicarboxylic aciduria [Tanaka (1972) J. Biol. Chem. 247, 7465-7478]. 3. Rats maintained on a diet containing clofibrate appeared normal after injection of hypoglycin, but had a marked dicarboxylic aciduria which was less than that induced in rats on a normal diet. 4. After administration of hypoglycin, buty

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Engel, Anna Maria, Ahmed H. El-Khatib, Martin Bachmann, et al. "Release of Hypoglycin A from Hypoglycin B and Decrease of Hypoglycin A and Methylene Cyclopropyl Glycine Concentrations in Ruminal Fluid Batch Cultures." Toxins 17, no. 2 (2025): 46. https://doi.org/10.3390/toxins17020046.

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The transformation of hypoglycin A (HGA), hypoglycin B (HGB), and methylene cyclopropyl glycine (MCPrG) in ruminal fluid batch cultures was investigated, and the effect of these toxins on the batch culture microorganisms using microbial metabolites was measured. An experiment was conducted using ovine ruminal fluid batch cultures and the ANKOM RF Gas Production System over four runs, each with an incubation period of 48 h. The fermenters contained 200 mg of (i) a substrate mixture (80% cellulose, 20% starch; CSM), (ii) CSM and 1.5 mL of a solution of pure toxins (a mixture of 500 ng/mL HGA and

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Golden, K. D., та E. A. Kean. "Dicarḃoxylic aciduria in hypoglycin poisoning". Clinical Nutrition 9, № 1 (1990): XXV. http://dx.doi.org/10.1016/0261-5614(90)90136-g.

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Pettenello, Martina, Zuzana Čriepoková, Natalia Rovňanová, Veronika Kostolániová, Igor Valocký, and Vladimír Hura. "Atypical myopathy in a horse: first confirmed case in Slovakia." Acta Veterinaria Brno 92, no. 3 (2023): 267–70. http://dx.doi.org/10.2754/avb202392030267.

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Atypical myopathy is an acute and often fatal rhabdomyolysis occurring in grazing horses, caused by ingestion of hypoglycin A, a toxin detected in the seeds and seedlings of sycamore trees. This article describes a case of atypical myopathy in a two-year-old Haflinger colt with clinical signs of weakness, muscle tremors, recumbency and esophageal obstruction. Despite intensive care, the clinical status deteriorated and given the poor prognosis, the horse was euthanized. Diagnosis of atypical myopathy was confirmed by increased concentrations of hypoglycin A and methylenecyclopropyl acetic acid

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Pitkin, Fabian, and Sala Randall. "Laboratory Patterns in Hypoglycin A Toxicity." Archives of Clinical and Biomedical Research 01, no. 02 (2017): 76–84. http://dx.doi.org/10.26502/acbr.5017008.

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8

Rendle, David. "‘Atypical’ myopathy — hypoglycin toxicity in horses." Livestock 21, no. 3 (2016): 188–93. http://dx.doi.org/10.12968/live.2016.21.3.188.

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Falloon, O’Neil C., Saheeda Mujaffar, and Donna Minott. "Physicochemical and Functional Properties of Protein Isolate from Ackee (Blighia sapida) Seed." West Indian Journal of Engineering 44, no. 2 (2022): 92–102. http://dx.doi.org/10.47412/ajtd3244.

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Ackee seeds are a major waste of the ackee canning industry. The seeds bio-accumulate the toxin hypoglycin but are also a potential source of protein. The objective of this study was to produce a protein isolate from the ackee seed and determine the chemical and functional properties of the isolate. Proteins were extracted from the defatted ackee seed flour using sodium borate buffer (pH 10.0, 50 mM) and aqueous ethanol (75% v/v). The protein isolate was then dried under vacuum and milled into a powder. The ackee seed protein isolate contained low molecular weight proteins comprising principal

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El-Khatib, Ahmed H., Anna Maria Engel, and Stefan Weigel. "Co-Occurrence of Hypoglycin A and Hypoglycin B in Sycamore and Box Elder Maple Proved by LC-MS/MS and LC-HR-MS." Toxins 14, no. 9 (2022): 608. http://dx.doi.org/10.3390/toxins14090608.

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Hypoglycin A (HGA) and methylenecyclpropylglycine (MCPrG) are formed by some maple trees (Acer species) and have been associated with incidences of atypical myopathy among horses in pastures. In this work, a simple and sensitive ultra-performance liquid chromatography tandem mass spectrometry (UPLC–MS/MS) method without derivatization was developed for the quantification of HGA and MCPrG in maple samples and validated according to EU guidelines. The LOQ presented here for HGA (16.4 µg/kg) is considerably lower than the lowest published LOQ (500 µg/kg). This method confirms that sycamore and bo

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Dissertations / Theses on the topic "Hypoglycin"

1

Bebbington, David. "Total synthesis of hypoglycin A." Thesis, University of Oxford, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.306112.

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Gair, Susan. "New approaches to the syntheses of nikkomycin B and hypoglycin A." Thesis, University of Newcastle Upon Tyne, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.363878.

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Carlier, Jérémy. "Implication médico-légale des toxiques d'origine végétale : approche analytique." Thesis, Lyon 1, 2014. http://www.theses.fr/2014LYO10221/document.

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Les intoxications ayant pour cause la prise de toxiques végétaux sont relativement fréquentes. Ces intoxications font suites à une ingestion accidentelle ou volontaire (aliments contaminés, préparations à but « thérapeutique », acte suicidaire, .). Le nombre de ces intoxications est sous-estimé car les signes cliniques sont souvent non spécifiques et les médecins méconnaissent la dangerosité des composés présents et l'incidence des intoxications par les plantes. La sous-estimation du nombre d'intoxications est également liée au manque de méthodes analytiques développées spécifiquement pour la

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Krägeloh, Tanja [Verfasser]. "Untersuchungen zur intestinalen Resorption von Hypoglycin A im Hinblick auf die Atypische Myopathie des Pferdes / Tanja Krägeloh." Hannover : Bibliothek der Tierärztlichen Hochschule Hannover, 2017. http://d-nb.info/113627961X/34.

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Book chapters on the topic "Hypoglycin"

1

"hypoglycin, n." In Oxford English Dictionary, 3rd ed. Oxford University Press, 2023. http://dx.doi.org/10.1093/oed/4029142973.

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Gordon, André. "Biochemistry of Hypoglycin and Toxic Hypoglycemic Syndrome." In Food Safety and Quality Systems in Developing Countries. Elsevier, 2015. http://dx.doi.org/10.1016/b978-0-12-801227-7.00004-4.

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Jackson-Malete, Jose, Orane Blake, and André Gordon. "Natural Toxins in Fruits and Vegetables: Blighia sapida and Hypoglycin." In Food Safety and Quality Systems in Developing Countries. Elsevier, 2015. http://dx.doi.org/10.1016/b978-0-12-801227-7.00002-0.

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D’mello, J. P. Felix. "Toxic compounds from fruit and vegetables." In Phytochemistry of Fruit and Vegetables. Oxford University PressOxford, 1997. http://dx.doi.org/10.1093/oso/9780198577904.003.0017.

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Abstract It is possible to adopt a very wide interpretation of this title, based on conventional meanings of the terms ‘fruit’ and ‘vegetables’. The Oxford dictionary defines fruit as ‘the edible product of a plant or tree, consisting of the seed and its envelope’. The definition for vegetables includes plants ‘cultivated for food’, particularly edible herbs or roots. If one also applies a broad definition for the phrase ‘toxic compounds’, then it is immediately apparent that we would be considering an almost infinite array of deleterious substances in the context of a wide variety of plant pr

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