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Relevant bibliographies by topics / Hyposmie

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Academic literature on the topic 'Hyposmie'

Author: Grafiati

Published: 4 June 2021

Last updated: 11 February 2022

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Journal articles on the topic "Hyposmie"

1

Plathow, C., and M. A. Weber. "Hyposmie und Epistaxis." Der Radiologe 44, no. 2 (February 1, 2004): 177–80. http://dx.doi.org/10.1007/s00117-003-0900-0.

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Weber, R., C. Raschka, and T. Bonzel. "Medikamentös-toxisch bedingte Hyposmie nach Lovastatin." Laryngo-Rhino-Otologie 71, no. 09 (September 1992): 483–84. http://dx.doi.org/10.1055/s-2007-997337.

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Bocksberger, S., W. Wagner, T. Hummel, W. Guggemos, M. Seilmaier, M. Hoelscher, and C. M. Wendtner. "Temporäre Hyposmie bei COVID-19-Patienten." HNO 68, no. 6 (May 25, 2020): 440–43. http://dx.doi.org/10.1007/s00106-020-00891-4.

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Liebler, S., C. Klingmann, B. Helmke, and P. K. Plinkert. "Bronchiale Obstruktion bei behinderter Nasenatmung und Hyposmie." Der Pneumologe 5, no. 3 (April 20, 2008): 183–86. http://dx.doi.org/10.1007/s10405-008-0234-8.

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Gudziol, H., and K. H. Gramowski. "Respirations-Olfaktometrie-eine objektivierende Methode zur quantitativen Bewertung einer Hyposmie." Laryngo-Rhino-Otologie 66, no. 11 (November 1987): 570–72. http://dx.doi.org/10.1055/s-2007-998737.

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Golding-Wood, David G., Mats Holmstrom, Yvonne Darby, Glenis K. Scadding, and Valerie J. Lund. "The treatment of hyposmia with intranasal steroids." Journal of Laryngology & Otology 110, no. 2 (February 1996): 132–35. http://dx.doi.org/10.1017/s0022215100132967.

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AbstractHyposmia is a neglected symptom in patients with rhinitis. We studied 25 patients presenting with perennial rhinitis. Fifteen patients expressed hyposmia as a significant symptom. University of Pennsylvania smell identification test (UPSIT) and visual analogue scales (VAS) were used to score the symptoms of hyposmia, nasal obstruction and nasal discharge before and after six weeks treatment with betamethasone sodium phosphate drops. Those patients with initial symptoms of hyposia significantly improved their UPSIT scores (p= 0.00009) and their VAS scores for hyposmia (p= 0.00133). Despite a significant decrease in the sensation of nasal obstruction, the non-hyposmics showed no increase in UPSIT scores after betamethasone therapy. There was no clear correlation between UPSIT results and other symptom scores. The judicious use of betamethasone drops in the treatment of rhinogenic hyposmia can be recommended.

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Lüers, Jan-Christoffer, Jens Peter Klußmann, and Orlando Guntinas-Lichius. "Die COVID-19-Pandemie und das HNO-Fachgebiet: Worauf kommt es aktuell an?" Laryngo-Rhino-Otologie 99, no. 05 (March 26, 2020): 287–91. http://dx.doi.org/10.1055/a-1095-2344.

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ZusammenfassungDie Übersichtarbeit fasst die aktuellen Erkenntnisse der Auswirkung der COVID-19-Pandemie für die Arbeit der HNO-Ärztin und des HNO-Arztes zusammen. Die aktuell diskutierte Rolle einer Anosmie oder Hyposmie als COVID-19-assoziiertes Symptom wird dargestellt. Wir diskutieren das klinische Management aller HNO-Fälle, aber insbesondere von COVID-19-erkrankten Patienten aus Sicht der HNO-Heilkunde. Ein besonderes Augenmerk gilt den Auswirkungen auf die HNO-Untersuchung und auf HNO-ärztliche Operationen.

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Pellegrino, R., A. Hahner, V. Bojanowski, C. Hummel, J. Gerber, and T. Hummel. "Olfactory function in patients with hyposmia compared to healthy subjects - An fMRI study." Rhinology journal 54, no. 4 (December 1, 2016): 374–81. http://dx.doi.org/10.4193/rhino16.098.

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Background: Individuals with hyposmia, or the partial loss of smell, represent a large sector (15 %) of the population that is likely to grow with the current aging population; however, our understanding to how hyposmics centrally process odors is still not clear. One popular non-invasive tool for in vivo imaging of biological activity among human brains has been function magnetic resonance imaging (fMRI) which uses blood-oxygenation level dependent (BOLD) signal as an indirect measurement. Therefore, the aim of this study was to understand differences in olfaction processing between patients with hyposmia and healthy controls using functional magnetic resonance imaging (fMRI). Methodology: Eleven hyposmic and 12 healthy, normosmic subjects were exposed to two different food-related odors (coffee and peach) during a block-designed fMRI session. Additionally, odor perception qualities were rated for each odor throughout the scanning session. Results: The activations of the normosmic group were localized in typical olfactory areas (insula, orbitofrontal cortex [OFC], limbic system and amygdala). The hyposmic group showed similar regions of activation (insula, OFC, limbic system), however, less activation was found in the amygdala, left anterior cingulate and right OFC, but higher activation was shown in the right parahippocampal and both the left and right posterior cingulate gyrus which are assumed to play an important role in the processing and remembrance of memories. Conclusions: These results indicate similar central olfactory processing among groups, yet subjects with partial loss may attempt to compensate smell impairment with odor memory or higher motivation to smell.

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Steurer, Johann. "Intranasale Steroide scheinen bei COVID-19-Kranken mit Anosmie oder Hyposmie keinen positiven Effekt zu haben." Praxis 110, no. 7 (May 2021): 415–16. http://dx.doi.org/10.1024/1661-8157/a003673.

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Goebel, L., B. Friesenhahn-Ochs, F. Bachelier, D. Kohn, and O. Lorbach. "Epiphyseolysis capitis femoris bei einem 23-jährigen Mann mit nicht diagnostiziertem hypogonadotropen Hypogonadismus." Osteologie 25, no. 02 (2016): 113–16. http://dx.doi.org/10.1055/s-0037-1619001.

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ZusammenfassungEin 23-jähriger Mann berichtete über seit zwei Monaten bestehende Schmerzen der rechten Hüfte ohne Trauma. Eine durchgeführte Röntgenuntersuchung wies eine Epiphyseolysis capitis femoris (ECF) rechts nach, sodass eine therapeutische Hüftkopfspickung rechts und eine prophylaktische Spickung links durchgeführt wurde. Bei kindlichem Habitus und gering ausgebildeten sekundären Geschlechtsmerkmalen erfolgte die Umfelddiagnostik. Das Skelettalter betrug 13,5 Jahre und die Knochendichtemessung wies eine hochgradige Osteoporose nach. Die endokrinologische Untersuchung erbrachte den Nachweis eines hypogonadotropen Hypogonadismus. Ein Mikrodadenom der Hypohyse, eine Hypoplasie des Bulbus olfactorius sowie des Sulcus olfactorius, eine Hodendysgenesie und eine hochgradige Hyposmie wurden nachgewiesen. Bei klinischem Verdacht auf ein Kallmann-Syndrom zeigte sich keine Mutation im KAL1-Gen. Eine Substitutionstherapie mit Testosteron und Cholecalciferol wurde eingeleitet. Zusammenfassend sind nur wenige Fälle über ECF bei Erwachsenen publiziert, allerdings muss auch an diese seltene Ursache von atypischen Hüftbeschwerden gedacht werden, insbesondere bei Patienten mit entsprechendem Risikoprofil.

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Dissertations / Theses on the topic "Hyposmie"

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Grüner, Eva [Verfasser], and Daniela [Akademischer Betreuer] Berg. "β-Amyloidplasmakonzentrationen und Hyposmie in Assoziation zur Entwicklung von Alzheimer-Demenz / Eva Grüner ; Betreuer: Daniela Berg." Tübingen : Universitätsbibliothek Tübingen, 2017. http://d-nb.info/1199547239/34.

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Reichmann, Heinz. "Clinical Criteria for the Diagnosis of Parkinson’s Disease." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-136567.

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The diagnosis of Parkinson’s disease (PD) follows the UK Brain Bank Criteria, which demands bradykinesia and one additional symptom, i.e. rigidity, resting tremor or postural instability. The latter is not a useful sign for the early diagnosis of PD, because it does not appear before Hoehn and Yahr stage 3. Early symptoms of PD which precede the onset of motor symptoms are hyposmia, REM sleep behavioral disorder, constipation, and depression. In addition, an increasing number of patients whose PD is related to a genetic defect are being described. Thus, genetic testing may eventually develop into a tool to identify at-risk patients. The clinical diagnosis of PD can be supported by levodopa or apomorphine tests. Imaging studies such as cranial CT or MRI are helpful to distinguish idiopathic PD from atypical or secondary PD. SPECT and PET methods are valuable to distinguish PD tremor from essential tremor if this is clinically not possible. Using all of these methods, we may soon be able to make a premotor diagnosis of PD, which will raise the question whether early treatment is possible and ethically and clinically advisable
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich

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Ngamsri, Theofanis [Verfasser], and Daniela [Akademischer Betreuer] Berg. "Hyposmie in Assoziation zu Risikofaktoren und prodromal Markern für Morbus Parkinson in einer Population älter als 50 Jahre / Theofanis Ngamsri ; Betreuer: Daniela Berg." Tübingen : Universitätsbibliothek Tübingen, 2016. http://d-nb.info/1165235471/34.

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Reichmann, Heinz. "Clinical Criteria for the Diagnosis of Parkinson’s Disease." Karger, 2010. https://tud.qucosa.de/id/qucosa%3A27712.

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The diagnosis of Parkinson’s disease (PD) follows the UK Brain Bank Criteria, which demands bradykinesia and one additional symptom, i.e. rigidity, resting tremor or postural instability. The latter is not a useful sign for the early diagnosis of PD, because it does not appear before Hoehn and Yahr stage 3. Early symptoms of PD which precede the onset of motor symptoms are hyposmia, REM sleep behavioral disorder, constipation, and depression. In addition, an increasing number of patients whose PD is related to a genetic defect are being described. Thus, genetic testing may eventually develop into a tool to identify at-risk patients. The clinical diagnosis of PD can be supported by levodopa or apomorphine tests. Imaging studies such as cranial CT or MRI are helpful to distinguish idiopathic PD from atypical or secondary PD. SPECT and PET methods are valuable to distinguish PD tremor from essential tremor if this is clinically not possible. Using all of these methods, we may soon be able to make a premotor diagnosis of PD, which will raise the question whether early treatment is possible and ethically and clinically advisable.
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich.

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5

Harke, Franziska [Verfasser]. "Die Betrachtung der vagalen, somatosensorisch evozierten Potentiale in einer Parkinsonrisikopopulation mit Mild Parkinsonian Signs - ein Vergleich mit den Prodromalmarkern Hyposmie und Obstipation in der Früherkennung der Parkinson-Krankheit / Franziska Harke." Tübingen : Universitätsbibliothek Tübingen, 2020. http://d-nb.info/1217249311/34.

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Taguchi, Tomoyuki. "α-Synuclein BAC transgenic mice exhibit RBD-like behaviour and hyposmia: a prodromal Parkinson’s disease model." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/263550.

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7

Giles, Luisa. "Endothelin-1 and oxygen saturation during exercise in normoxia and hyposia." Thesis, University of British Columbia, 2007. http://hdl.handle.net/2429/32612.

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We tested the hypothesis that decrements in arterial oxyhaemoglobin saturation could be related to elevations in circulating endothelin-1 following 30 minutes of exercise at ventilatory threshold. Eight aerobically trained males (mean ± SEM: age 26.14 ± 1.77 years, height 182.36 ± 1 . 5 1 cm, mass 72.89 ± 2.62 kg) completed 2 maximal exercise tests (mean ± SEM: normoxia (n) 68.56 ± 2.06 mL.kg-¹min-¹; hypoxia (Fi02 0.14)(h) 53.88 ± 1.35 mL.kg-¹.min-¹), and two 30-minute steady state exercise protocols at the power achieved at threshold during maximal exercise tests (mean ± SEM: power (Watts) 257.14 ± 21.57 (n) 191.25 ± 10.79 (Fi02 0.14)(h); HR (bpm) 161.7 ± 5.34 (n) 156.6 ± 3.45 (h)). When participants exercised for 30 minutes at ventilatory threshold inspiring 14%02, a significant decrease in oxygen saturation (as measured by pulse oximetry) was observed, when compared to values in normoxia (80.2 ± 1.17 % (h) vs 94.12 ± 0.24 % (n); p<0.001). This desaturation was not accompanied by significant changes in plasma endothelin-1 (ET-1), big endothelin-1 (BigET-1) or nitric oxide (NO). Both pulmonary artery pressure (PAP) and oscillatory compliance (OC) were significantly greater following exercise (F[superscript omitted] = 4.74 p< 0.05), compared to pre-exercise values. These outcome variables were not different between normoxia and hypoxia. Plasma ET-1 or BigET-1 levels did not differ significantly over time or across conditions F[superscript omitted] = 4.74 p> 0.05). In conclusion, plasma ET-1 levels following 30-minutes of steady state exercise at ventilatory threshold are unrelated to decrements in oxyhaemoglobin saturation.
Education, Faculty of
Kinesiology, School of
Graduate

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8

Hedén, Blomqvist Ebba. "Evaluation of medical and/or surgical treatment of anosmia/hyposmia in association with inflammatory disease of the upper airway /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-930-7.

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Bailie, Jason M. "The Influence of Odorant Intensity on Odor Identification in Older Adults." University of Cincinnati / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1250010194.

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Mariño, Franklin. "Pérdida del sentido del olfato: profundizando en su epidemiología, causas rinosinusales y posibilidades terapéuticas." Doctoral thesis, Universitat de Barcelona, 2014. http://hdl.handle.net/10803/291110.

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FUNDAMENTO: A pesar de la importancia del olfato para la nutrición, seguridad y calidad de vida, la prevalencia y factores de riesgo del deterioro olfativo en nuestra población no han sido bien estudiados. La patología inflamatoria nasosinusal (rinitis/rinosinusitis) causa disfunción olfatoria y, aunque existe asociación entre patología nasosinusal y bronquial, se desconoce si la pérdida del olfato puede constituir un factor diagnóstico. También se desconoce si el tratamiento médico mejora el olfato de los pacientes con rinitis alérgica persistente, si el entrenamiento olfativo puede mejorar el sentido del olfato o si la resección del neuroepitelio olfatorio en la cirugía de base de cráneo puede alterarlo. HIPÓTESIS: Existe alta prevalencia de pérdida olfativa en la población general, a veces asociada a enfermedades inflamatorias nasales asociadas a patología broncopulmonar y a la cirugía endoscópica nasosinusal de base de cráneo. El tratamiento médico y el entrenamiento olfativo pueden mejorar las aptitudes olfatorias. OBJETIVOS: 1º) Determinar la prevalencia de pérdida del olfato y los factores de riesgo asociados en la población general. 2º) Estudiar la pérdida del olfato como factor diagnóstico de la patología nasal y broncopulmonar asociada, y como efecto adverso de la cirugía de base de cráneo. 3º) Analizar el efecto del tratamiento de la patología nasal y del entrenamiento olfativo sobre la función olfatoria. METODOLOGÍA: Correspondiente a 5 estudios: 1º) dos cuestionarios (olfato y demografía) y 4 olores microencapsulados distribuidos en población general mediante un periódico (250.000 ejemplares). 2º) Olfatometría comparando enólogos y controles. 3º) Función olfatoria comparando pacientes con bronquiectasias y controles. 4º) Síntomas nasales y olfatometría en pacientes con rinitis alérgica persistente antes y después del tratamiento con levocetirizina. 5º) Síntomas nasales y olfatometría en pacientes intervenidos de tumores de base de cráneo por abordaje endoscópico nasosinusal. RESULTADOS: Extensos resultados publicados en 5 artículos: BMJ Open 2012, Rhinology 2010, RespMed 2011, Int Arch Allergy Immunol 2012, Neurosurgery 2012. CONCLUSIONES: 1º) Existe una alta prevalencia de hiposmia (19%) y anosmia (0,3%) en la población general, aunque sólo el 7% de los sujetos considera tener un sentido del olfato pobre. 2º) La capacidad de detección olfativa se deteriora progresivamente a lo largo de la vida, pero las habilidades cognitivas olfativas se incrementan con la experiencia adquirida en las primeras décadas de la vida para posteriormente decaer a partir de la sexta década de vida. 3º) El sentido del olfato de las mujeres es superior al de los hombres para todas las edades.4º) El embarazo, el sexo masculino, la mala auto-valoración del olfato, un bajo nivel educativo y el envejecimiento son factores de riesgo para la pérdida del sentido del olfato; mientras que la exposición a sustancias tóxicas y fumar son factores protectores moderados. 5º Gracias al entrenamiento y la experiencia, los enólogos poseen una mayor capacidad de identificación. pero no de detección, olfativa que las personas no entrenadas. 6º Existe un claro deterioro de la función olfativa en los pacientes con bronquiectasias en comparación con controles sanos, particularmente en los pacientes afectos de rinosinusitis crónica, poliposis nasal e inmunodeficiencia humoral primaria. 7º) La levocetirizina mejora la pérdida del olfato medida por EVA en pacientes con rinitis alérgica persistente después de 7 días de tratamiento gracias a la disminución de la inflamación nasal. 8º) El abordaje endonasal extendido, pero no el abordaje transnasal transesfenoidal endosópico, tiene un impacto negativo a corto plazo (3 meses) en el sentido del olfato de los pacientes sometidos a cirugía de base de cráneo.
INTRODUCTION: Despite the importance of smell for nutrition, safety and quality of life, the prevalence and risk factors of olfactory impairment in our population have not been well studied. Although there is an association between sinus and bronchial disease, it is not known whether hyposmia can be a diagnostic factor or not. It is also unknown if medical treatment improves smell loss in patients with persistent allergic rhinitis, if olfactory training can improve smell function or if skull base surgery can alter it. HYPOTHESIS: There is a high prevalence of olfactory loss in general population, sometimes associated with bronchopulmonary pathology and endoscopic skull base surgery. Medical treatment and olfactory training can improve smell skills. OBJECTIVES: 1)To report the prevalence of loss of smell and associated risk factors in the general population. 2)To study the loss of smell as a diagnostic tool in the sinonasal and bronchial associated disease, and as a side effect of skull base surgery. 3)To analyze the effect of treatment of nasal inflammatory conditions and training on olfactory function. METHODOLOGY: Corresponding to 5 studies: 1)Two questionnaires (smell and demography) and 4 smells microencapsulated odorants distributed through a newspaper (250,000 copies). 2)Olfactometry in enologists and untrained subjects. 3)Olfactory function in patients with bronchiectasis and controls. 4)Nasal Symptoms and olfactometry in patients with persistent allergic rhinitis before and after treatment with levocetirizine. 5)Nasal Symptoms and olfactometry in patients undergoing skull base tumors by endoscopic sinus approach. RESULTS AND CONCLUSIONS: 1)There is a high prevalence of hyposmia (19%) and anosmia (0.3%) in the general population 2)Smell detection deteriorates throughout life. 3)Women are superior to men in smell abilities. 4)Pregnancy, male gender, poor self-reported sense of smell, low educational level and aging are risk factors for loss of smell; while exposure to toxic substances and smoking are moderate protective factors. 5) Enologists have a superior smell identification than untrained subjects. 6)Patients with bronchiectasis have a deteriorated sense of smell compared to healthy controls. 7)Levocetirizine improves olfactory loss in patients with persistent allergic rhinitis 8)Expanded endonasal approach has a short term negative impact in smell function of patients undergoing skull base surgery.

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Book chapters on the topic "Hyposmie"

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Smith, David V., and Heather J. Duncan. "Primary Olfactory Disorders: Anosmia, Hyposmia, and Dysosmia." In Science of Olfaction, 439–66. New York, NY: Springer New York, 1992. http://dx.doi.org/10.1007/978-1-4612-2836-3_16.

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Saiz-Sanchez, Daniel, Carlos de la Rosa-Prieto, Isabel Ubeda-Banon, and Alino Martinez-Marcos. "Neural Basis of Hyposmia in Alzheimer’s Disease." In The Clinical Spectrum of Alzheimer's Disease -The Charge Toward Comprehensive Diagnostic and Therapeutic Strategies. InTech, 2011. http://dx.doi.org/10.5772/18169.

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B., Alessandra, Marco Fusetti, and Alberto Eibenstei. "The Predictive Role of Hyposmia in Alzheimer's Disease." In The Clinical Spectrum of Alzheimer's Disease -The Charge Toward Comprehensive Diagnostic and Therapeutic Strategies. InTech, 2011. http://dx.doi.org/10.5772/18256.

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Rovini, Erika, Dario Esposito, Carlo Maremmani, Paolo Bongioanni, and Filippo Cavallo. "Empowering Patients in Self-Management of Parkinson's Disease Through Cooperative ICT Systems." In Wearable Technologies, 637–63. IGI Global, 2018. http://dx.doi.org/10.4018/978-1-5225-5484-4.ch028.

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The objective of this chapter is to demonstrate the technical feasibility and medical effectiveness of personalised services and care programmes for Parkinson's disease, based on the combination of mHealth applications, cooperative ICTs, cloud technologies and wearable integrated devices, which empower patients to manage their health and disease in cooperation with their formal and informal caregivers, and with professional medical staff across different care settings, such as hospital and home. The presented service revolves around the use of two wearable inertial sensors, i.e. SensFoot and SensHand, for measuring foot and hand performance in the MDS-UPDRS III motor exercises. The devices were tested in medical settings with eight patients, eight hyposmic subjects and eight healthy controls, and the results demonstrated that this approach allows quantitative metrics for objective evaluation to be measured, in order to identify pre-motor/pre-clinical diagnosis and to provide a complete service of tele-health with remote control provided by cloud technologies.

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Rovini, Erika, Dario Esposito, Carlo Maremmani, Paolo Bongioanni, and Filippo Cavallo. "Empowering Patients in Self-Management of Parkinson's Disease through Cooperative ICT Systems." In Advances in Medical Technologies and Clinical Practice, 251–77. IGI Global, 2016. http://dx.doi.org/10.4018/978-1-4666-9530-6.ch010.

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The objective of this chapter is to demonstrate the technical feasibility and medical effectiveness of personalised services and care programmes for Parkinson's disease, based on the combination of mHealth applications, cooperative ICTs, cloud technologies and wearable integrated devices, which empower patients to manage their health and disease in cooperation with their formal and informal caregivers, and with professional medical staff across different care settings, such as hospital and home. The presented service revolves around the use of two wearable inertial sensors, i.e. SensFoot and SensHand, for measuring foot and hand performance in the MDS-UPDRS III motor exercises. The devices were tested in medical settings with eight patients, eight hyposmic subjects and eight healthy controls, and the results demonstrated that this approach allows quantitative metrics for objective evaluation to be measured, in order to identify pre-motor/pre-clinical diagnosis and to provide a complete service of tele-health with remote control provided by cloud technologies.

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Masayuki, Karaki, Kobayashi Eiji, Touge Tetsuo, and Mori Nozomu. "Evaluation of Olfactory Impairment in Parkinson’s Disease Using Near-Infrared Spectroscopy." In Advances in Bioinformatics and Biomedical Engineering, 293–302. IGI Global, 2013. http://dx.doi.org/10.4018/978-1-4666-2113-8.ch030.

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Hyposmia, psychiatric disorders, and cognitive problems are common non-motor manifestations of Parkinson’s disease (PD), but how they are related to the progression of PD remains unclear. Olfactory dysfunction, which is a common non-motor symptom of Parkinson’s disease, is considered to be an early manifestation of this disease. The aim of this study is to investigate the usefulness of near-infrared spectroscopy (NIRS) in measuring olfaction in PD patients and to establish the cortical basis of olfactory function in PD patients. This study was conducted on 9 healthy normosmic volunteers and 24 patients with PD. The authors employed a 22-channel NIRS device with eight light-incident fibers and seven light-detection fibers and placed fibers every 2.5 cm on the forehead of volunteers. Isovaleric acid was used as the odor stimulant. The authors measured the changes in total hemoglobin (tHb) concentration from baseline values and compared the results obtained from healthy normosmic volunteers with those from PD patients. PD patients had higher scores in the subjective olfactory test and smaller changes in tHb concentrations compared with normal volunteers. In particular, no changes in tHb concentration were detected in patients with the awareness of the sense of smell disorder.

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"Germany France Nether United lands Kingdom mathematical gean.mean gecm.mean gecm. gecm.mean procedure graphic. graphic. graphic. graphic. probit-analysis Table 3; Mathematical treatment of threshold data 5. SELECTION OF PMALISTS 5.1 Requirement for panelists Panlists are required to have the following qualities: - sensitivity: subjects with specific anosmia or hyposmia must be ex cluded. - physical condition: subjects whose sense of smell is temporarily im paired by desease must be excluded. - reliability: subjects must be able to reproduce accurate results con sistently. - honesty: subjects must exactly say what they perceive. Germany France Nether United lands Kingdom Sensitivity "normal" 5 reference not too actual odor sense, age odors range good, not or key carp. 18-50 y. 1:1000 too bad Physical condition quest. quest. Reliability repeated measures with H2S Honesty 20% errors Table 4: Selection of panelists Olfactory sensitivity for one individual varies about factor three due to climatological, physiological, environmental reaons etc. The sensory sensitivity also varies from odorant to odorant. So it is difficult to select a panel with a sensitivity distribution similar to that of the population. The preferred method in the United Kingdom for screening panelists uses the actual odor to be tested as a key component. In France selection is carried out on the basis of the threshold for five standard odor ants. In Germany a "normal11 sense of smell is requested of persons between the age of 18 and 50 years, in the Netherlands no exact specifi cations are given. Anyway, an extreme clustering around the mean or to wards the extremes has to be avoided." In Odour Prevention and Control of Organic Sludge and Livestock Farming, 73. CRC Press, 1986. http://dx.doi.org/10.1201/9781482286311-27.

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Conference papers on the topic "Hyposmie"

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Pamfil, C., S. Rednic, I. Catana, M. Deac Badaranza, D. Balint Gib, P. Vele, L. Bene, and L. Damian. "PS10:182 Nmda-positive neuropsychiatric lupus manifesting as weight increase and hyposmia." In 11th European Lupus Meeting, Düsseldorf, Germany, 21–24 March 2018, Abstract presentations. Lupus Foundation of America, 2018. http://dx.doi.org/10.1136/lupus-2018-abstract.224.

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Sedaghat, A., I. Gengler, M. Speth, and K. Phillips. "Dissecting of chronic rhinosinusitis nasal symptoms to determine the significance of hyposmia in disease control." In Abstract- und Posterband – 91. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn – Welche Qualität macht den Unterschied. © Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0040-1711368.

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Krug, D., MT van Mackelenbergh, T. Heilmann, M. Elessawy, A. Schreiber, J. Zimmer, AD Boicev, et al. "Unerwünschte Ereignisse und Hautreaktionen in der HYPOSIB - Studie (ARO 2013-05): Daten des Sicherheitsbericht 2019." In 40. Jahrestagung der Deutschen Gesellschaft für Senologie e.V. © Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0040-1710641.

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Krug, D., D. Olbrich, R. Vonthein, A. Illen, IR König, K. Dellas, and J. Dunst. "Fraktionierung und Prognosefaktoren in der HYPOSIB-Studie – Hypofraktionierung mit simultan-integriertem Boost versus Standard-Fraktionierung beim Mammakarzinom." In 39. Jahrestagung der Deutschen Gesellschaft für Senologie. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1688013.

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Krug, D., MT van Mackelenbergh, T. Heilmann, M. Elessawy, A. Schreiber, J. Zimmer, AD Boicev, et al. "Wie empfinden und bewerten Patientinnen mit Mammakarzinom die einzelnen Therapiemodalitäten: Ergebnisse einer Patientenbefragung im Rahmen der HYPOSIB - Studie (ARO 2013-05)." In 40. Jahrestagung der Deutschen Gesellschaft für Senologie e.V. © Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0040-1710640.

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