Relevant bibliographies by topics / Hypothalamic Pituitary Adrenal Axis (HPA)

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Hypothalamic Pituitary Adrenal Axis (HPA)'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Hypothalamic Pituitary Adrenal Axis (HPA)"

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Keller‐Wood, Maureen. "Hypothalamic‐Pituitary‐Adrenal Axis—Feedback Control." Comprehensive Physiology 5, no. 3 (2015): 1161–82. https://doi.org/10.1002/j.2040-4603.2015.tb00644.x.

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ABSTRACTThe hypothalamo‐pituitary‐adrenal axis (HPA) is responsible for stimulation of adrenal corticosteroids in response to stress. Negative feedback control by corticosteroids limits pituitary secretion of corticotropin, ACTH, and hypothalamic secretion of corticotropin‐releasing hormone, CRH, and vasopressin, AVP, resulting in regulation of both basal and stress‐induced ACTH secretion. The negative feedback effect of corticosteroids occurs by action of corticosteroids at mineralocorticoid receptors (MR) and/or glucocorticoid receptors (GRs) located in multiple sites in the brain and in the
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Miller, Walter L. "The Hypothalamic-Pituitary-Adrenal Axis: A Brief History." Hormone Research in Paediatrics 89, no. 4 (2018): 212–23. http://dx.doi.org/10.1159/000487755.

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The hypothalamic-pituitary-adrenal (HPA) axis is central to homeostasis, stress responses, energy metabolism, and neuropsychiatric function. The history of this complex system involves discovery of the relevant glands (adrenal, pituitary, hypothalamus), hormones (cortisol, corticotropin, corticotropin-releasing hormone), and the receptors for these hormones. The adrenal and pituitary were identified by classical anatomists, but most of this history has taken place rather recently, and has involved complex chemistry, biochemistry, genetics, and clinical investigation. The integration of the HPA
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Taheri, Serpil, Züleyha Karaca, Ecmel Mehmetbeyoglu, et al. "The Role of Apoptosis and Autophagy in the Hypothalamic-Pituitary-Adrenal (HPA) Axis after Traumatic Brain Injury (TBI)." International Journal of Molecular Sciences 23, no. 24 (2022): 15699. http://dx.doi.org/10.3390/ijms232415699.

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Traumatic brain injury (TBI) is a major health problem affecting millions of people worldwide and leading to death or permanent damage. TBI affects the hypothalamic–pituitary–adrenal (HPA) axis either by primary injury to the hypothalamic–hypophyseal region or by secondary vascular damage, brain, and/or pituitary edema, vasospasm, and inflammation. Neuroendocrine dysfunctions after TBI have been clinically described in all hypothalamic–pituitary axes. We established a mild TBI (mTBI) in rats by using the controlled cortical impact (CCI) model. The hypothalamus, pituitary, and adrenals were col
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Musselman, Dominique L., and Charles B. Nemeroff. "Depression and Endocrine Disorders: Focus on the Thyroid and Adrenal System." British Journal of Psychiatry 168, S30 (1996): 123–28. http://dx.doi.org/10.1192/s0007125000298504.

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Of the various hypothalamic–pituitary–end organ axes, the thyroid and adrenal systems have been implicated most often in affective disorders. Patients with primary thyroid disease have high rates of depression, and patients with Addison's disease or Cushing's syndrome have relatively high rates of affective and anxiety symptoms. However, the major support for these endocrine axes in the pathophysiology of mood disorders comes from studies in which alterations in components of the hypothalamic–pituitary–thyroid (HPT) and the hypothalamic–pituitary–adrenal (HPA) axes have been documented in pati
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Gupta, Deepashree, and John E. Morley. "Hypothalamic‐Pituitary‐Adrenal (HPA) Axis and Aging." Comprehensive Physiology 4, no. 4 (2014): 1495–510. https://doi.org/10.1002/j.2040-4603.2014.tb00585.x.

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AbstractHuman aging is associated with increasing frailty and morbidity which can result in significant disability. Dysfunction of the hypothalamic‐pituitary‐adrenal (HPA) axis may contribute to aging‐related diseases like depression, cognitive deficits, and Alzheimer's disease in some older individuals. In addition to neuro‐cognitive dysfunction, it has also been associated with declining physical performance possibly due to sarcopenia. This article reviews the pathophysiology of HPA dysfunction with respect to increased basal adrenocorticotropic hormone (ACTH) and cortisol secretion, decreas
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Zhou, Bei, Qilong Xu, Junjie Guo, et al. "Necroptosis Contributes to LPS-Induced Activation of the Hypothalamic-Pituitary-Adrenal Axis in a Piglet Model." International Journal of Molecular Sciences 23, no. 19 (2022): 11218. http://dx.doi.org/10.3390/ijms231911218.

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Stressors cause activation of the hypothalamic-pituitary-adrenal (HPA) axis and a systemic inflammatory response. As a newly proposed cell death manner in recent years, necroptosis occurs in a variety of tissue damage and inflammation. However, the role of necroptosis in HPA axis activation remains to be elucidated. The aim of this study was to investigate the occurrence of necroptosis and its role in HPA activation in a porcine stress model induced by Escherichia coli lipopolysaccharide (LPS). Several typical stress behaviors like fever, anorexia, shivering and vomiting were observed in pigle
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Müller, Helge, Juliane Kröger, Olaf Jöhren, et al. "Stress sensitivity is increased in transgenic rats with low brain angiotensinogen." Journal of Endocrinology 204, no. 1 (2009): 85–92. http://dx.doi.org/10.1677/joe-09-0363.

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AT1 blockers attenuate hypothalamo-pituitary–adrenal (HPA) axis reactivity in hypertension independently of their potency to lower blood pressure. A reduced pituitary sensitivity to CRH and a downregulation of hypothalamic CRH expression have been suggested to influence HPA axis activity during chronic AT1 blockade. This study was aimed at confirming the role of central angiotensin II in regulating HPA reactivity by using the transgenic rat TGR(ASrAOGEN), a model featuring low levels of brain angiotensinogen. Different stress tests were performed to determine HPA reactivity in TGR(ASrAOGEN) an
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Sattler, Janko, Jinwen Tu, Shihani Stoner та ін. "Role of 11β-HSD type 1 in abnormal HPA axis activity during immune-mediated arthritis". Endocrine Connections 7, № 2 (2018): 385–94. http://dx.doi.org/10.1530/ec-17-0361.

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Patients with chronic immune-mediated arthritis exhibit abnormal hypothalamo-pituitary-adrenal (HPA) axis activity. The basis for this abnormality is not known. Immune-mediated arthritis is associated with increased extra-adrenal synthesis of active glucocorticoids by the 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme. 11β-HSD1 is expressed in the central nervous system, including regions involved in HPA axis regulation. We examined whether altered 11β-HSD1 expression within these regions contributes to HPA axis dysregulation during arthritis. The expression of 11β-HSD1, and other c
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Qadri, Fatimunnisa, Florian Rimmele, Lisa Mallis, et al. "Acute hypothalamo-pituitary-adrenal axis response to LPS-induced endotoxemia: expression pattern of kinin type B1 and B2 receptors." Biological Chemistry 397, no. 2 (2016): 97–109. http://dx.doi.org/10.1515/hsz-2015-0206.

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Abstract Bradykinin (BK) and des-Arg9-BK are pro-inflammatory mediators acting via B2 (B2R) and B1 (B1R) receptors, respectively. We investigated the role of B2R and B1R in lipopolysaccharide (LPS)-induced hypothalamo-pituitary-adrenal (HPA) axis activation in SD rats. LPS given intraperitoneally (ip) up-regulated B1R mRNA in the hypothalamus, both B1R and B2R were up-regulated in pituitary and adrenal glands. Receptor localization was performed using immunofluorescence staining. B1R was localized in the endothelial cells, nucleus supraopticus (SON), adenohypophysis and adrenal cortex. B2R was
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Quinn, Matthew, Yoshiyuki Ueno, Hae Yong Pae, et al. "Suppression of the HPA axis during extrahepatic biliary obstruction induces cholangiocyte proliferation in the rat." American Journal of Physiology-Gastrointestinal and Liver Physiology 302, no. 1 (2012): G182—G193. http://dx.doi.org/10.1152/ajpgi.00205.2011.

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Cholestatic patients often present with clinical features suggestive of adrenal insufficiency. In the bile duct-ligated (BDL) model of cholestasis, the hypothalamic-pituitary-adrenal (HPA) axis is suppressed. The consequences of this suppression on cholangiocyte proliferation are unknown. We evaluated 1) HPA axis activity in various rat models of cholestasis and 2) effects of HPA axis modulation on cholangiocyte proliferation. Expression of regulatory molecules of the HPA axis was determined after BDL, partial BDL, and α-naphthylisothiocyanate (ANIT) intoxication. The HPA axis was suppressed b
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Dissertations / Theses on the topic "Hypothalamic Pituitary Adrenal Axis (HPA)"

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Kalyani, Manu. "Interaction between Prolactin and the Hypothalamic-Pituitary-Adrenal (HPA) axis." Miami University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=miami1397233916.

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Heinzmann, Jan-Michael. "Central and peripheral aspects of hypothalamic-pituitary-adrenal (HPA) axis dysfunction." Diss., lmu, 2012. http://nbn-resolving.de/urn:nbn:de:bvb:19-150032.

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Bakirtzi, Georgia. "Epigenetic regulation of POMC : implications for the hypothalamic-pituitary-adrenal (HPA) axis." Thesis, University of Sheffield, 2015. http://etheses.whiterose.ac.uk/9455/.

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Seale, Josephine Victoria. "Gonadal steroids : modulators of hypothalamo-pituitary-adrenal (HPA) axis activity throughout life." Thesis, University of Bristol, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.414189.

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Evanson, Nathan K. "Rapid regulation of the hypothalamus-pituitary-adrenal axis by glutamate and glucocorticoids." Cincinnati, Ohio : University of Cincinnati, 2008. http://rave.ohiolink.edu/etdc/view.cgi?acc_num=ucin1227289026.

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Thesis (Ph.D.)--University of Cincinnati, 2008.<br>Advisor: James Herman PhD (Committee Chair), Randall Sakai PhD (Committee Member), Stephen Woods PhD (Committee Member), David D'Alessio MD (Committee Member), Yvonne Ulrich-Lai PhD (Committee Member). Title from electronic thesis title page (viewed Feb. 9, 2009). Keywords: HPA axis; glutamate; cannabinoids; nongenomic; glucocorticoids. Includes abstract. Includes bibliographical references.
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Dettmer, Amanda M. "Early rearing experience, hypothalamic-pituitary-adrenal (HPA) activity, and serotonin transporter genotype influences on the development of anxiety in infant rhesus monkeys (Macaca mulatta) /." Amherst, Mass. : University of Massachusetts Amherst, 2009. http://scholarworks.umass.edu/open_access_dissertations/45/.

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Janse, van Vuuren Marthinus. "Hypothalamic-pituitary-adrenal-axis vs. the sympatho-adrenal medullary system in the acute response to psychological stress." Thesis, Stellenbosch : University of Stellenbosch, 2011. http://hdl.handle.net/10019.1/6738.

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Thesis (MSc (Physiological Sciences))--University of Stellenbosch, 2011.<br>Includes bibliography.<br>ENGLISH ABSTRACT: The hypothalamic-pituitary-adrenal-(HPA) axis has long been closely associated with psychological stress-induced activation of the adrenal cortex and subsequent glucocorticoid production. Another, less known peripheral limb of the psychological stress response, is the sympatho adrenal medullary pathway. We hypothesized that the sympatho-adrenal medullary system constitutes the primary response to acute psychological stress, with the HPA-axis functioning as a secondary re
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Nayar, Shweta. "NOCICEPTIN/ORPHANIN FQ (N/OFQ) REGULATION OF THE STRESS RESPONSE: INTERACTION BETWEEN PROLACTIN AND THE HYPOTHALAMIC-PITUITARY-ADRENAL (HPA) AXIS." Miami University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=miami1382509698.

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Finn, David Patrick. "Monoamines and the neuroendocrine response to stress : the role of imidazoline I₂ binding sites and α₂-adrenoceptors." Thesis, University of Bristol, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.340303.

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Gordon, Jennifer. "Depression, the dynamic function of the autonomic nervous system and hypothalamic-pituitary-adrenal (HPA) axis, and cardiovascular disease." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=110429.

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Depression is associated with an increased risk of cardiovascular disease (CVD). One possible mechanism of this effect is dysregulation of the biological stress systems, the autonomic nervous system (ANS) and hypothalamic-pituitary-adrenal (HPA) axis. The current thesis aimed to better understand the relationship between depression and these two systems. In the first study, the effect of major depression on heart rate recovery following exercise, a marker of ANS tone, was examined in cardiac patients. Depression was associated with poor early heart rate recovery, suggesting reduced post-exerci
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Books on the topic "Hypothalamic Pituitary Adrenal Axis (HPA)"

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Geer, Eliza B., ed. The Hypothalamic-Pituitary-Adrenal Axis in Health and Disease. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-45950-9.

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F, Schatzberg Alan, Nemeroff Charles B, and American College of Neuropsychopharmacology. Meeting, eds. The Hypothalamic-pituitary-adrenal axis: Physiology, pathophysiology, and psychiatric implications. Raven Press, 1988.

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C, Gaillard Rolf, ed. The ACTH axis: Pathogenesis, diagnosis, and treatment. Kluwer Academic Publishers, 2003.

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F, Ganong William, Dallman M. F, Roberts James Lewis 1951, Krieger Dorothy T, Herbert E. 1926-, and New York Academy of Sciences., eds. The Hypothalamic-pituitary-adrenal axis revisited: A symposium in honor of Dorothy Krieger and Edward Herbert. New York Academy of Sciences, 1987.

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T, Podvigina T., та Filaretova L. P, ред. Adaptat͡s︡ii͡a︡ kak funkt͡s︡ii͡a︡ gipofizarno-adrenokortikalʹnoĭ sistemy. "Nauka", 1994.

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Abebe, Getachew. The integrity of the hypothalamic-pituitary-adrenal axis in Boran (Bos indicus) cattle infected with Trypanosoma congolense. Brunel University, 1991.

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Siller, Stefanie. Epigenetic modification of the hypothalamic-pituitary-adrenal axis during early life of the house sparrow (Passer domesticus). [publisher not identified], 2022.

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Banjanin, Sonja. Effects of repeated antenatal dexamethasone (dex) exposure on hypothalamic-pituitary-adrenal (HPA) function in mature adult guinea pigs (Cavis porcellus). National Library of Canada, 2003.

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Castro-Diehl, Olga Cecilia. Association of Sleep Duration and Quality with Activation of Two Neuroendocrine Systems: Hypothalamic-Pituitary-Adrenal Axis and Sympathetic Nervous System. The Multi-Ethnic Study of Atherosclerosis (MESA). [publisher not identified], 2016.

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K, Lüdecke Dieter, Chrousos George P, Tolis George, and International Symposium on Challenges of Hypersecretion: ACTH, Cushing's Syndrome, and Other Hypercortisolemic States (2nd : 1989 : Crete, Greece), eds. ACTH, Cushing's syndrome, and other hypercortisolemic states. Raven Press, 1990.

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Book chapters on the topic "Hypothalamic Pituitary Adrenal Axis (HPA)"

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Sainburg, Robert L., Andrew L. Clark, George E. Billman, et al. "Hypothalamus-Pituitary-Adrenal (HPA) Axis." In Encyclopedia of Exercise Medicine in Health and Disease. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-540-29807-6_3113.

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Tsakiri, Sophia P., George P. Chrousos, and Andrew N. Margioris. "Molecular Development of the Hypothalamic-Pituitary-Adrenal (HPA) Axis." In Developmental Endocrinology. Humana Press, 2002. http://dx.doi.org/10.1007/978-1-59259-156-5_16.

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Daskalakis, Nikolaos P., Marlon A. McGill, Amy Lehrner, and Rachel Yehuda. "Endocrine Aspects of PTSD: Hypothalamic-Pituitary-Adrenal (HPA) Axis and Beyond." In Comprehensive Guide to Post-Traumatic Stress Disorders. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-08359-9_130.

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Daskalakis, Nikolaos P., Marlon A. McGill, Amy Lehrner, and Rachel Yehuda. "Endocrine Aspects of PTSD: Hypothalamic-Pituitary-Adrenal (HPA) Axis and Beyond." In Comprehensive Guide to Post-Traumatic Stress Disorder. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-08613-2_130-1.

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Ramírez, Francisco, and Don Mason. "Corticosterone and the hypothalamic-pituitary-adrenal (HPA) axis in autoimmune diseases." In Steroid Hormones and the T-Cell Cytokine Profile. Springer London, 1997. http://dx.doi.org/10.1007/978-1-4471-0931-0_7.

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Gupta, Ankush. "Role of Stress and Hormones of the Hypothalamic-Pituitary-Adrenal (HPA) Axis in Aging." In Models, Molecules and Mechanisms in Biogerontology. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-3585-3_12.

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Maguire, Jamie. "GABAergic Control of the Hypothalamic–Pituitary–Adrenal (HPA) Axis: Role of Extrasynaptic GABAA Receptors." In Extrasynaptic GABAA Receptors. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1426-5_12.

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Lv, Qiufeng, Gonglin Dong, Shuang Cao, et al. "Effects of Taurine on Blood Index of Hypothalamic Pituitary Adrenal (HPA) Axis of Stress-Induced Hypertensive Rat." In Taurine 9. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-15126-7_49.

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Kyrou, Ioannis, and Constantine Tsigos. "Hypothalamic-Pituitary-Adrenal Axis." In Adrenal Glands. Springer Berlin Heidelberg, 2005. http://dx.doi.org/10.1007/3-540-26861-8_3.

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Heaney, Jennifer. "Hypothalamic-Pituitary-Adrenal Axis." In Encyclopedia of Behavioral Medicine. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-39903-0_460.

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Conference papers on the topic "Hypothalamic Pituitary Adrenal Axis (HPA)"

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"From poverty to depression to inflammation: a literature review." In International Conference on Public Health and Humanitarian Action. International Federation of Medical Students' Associations - Jordan, 2022. http://dx.doi.org/10.56950/ovii9740.

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Background: Depression is the most commonly presented psychiatric disorder1 . People with low socioeconomic status are more likely to experience depression compared to those with higher socioeconomic status2 . Recent studies have revealed that people experiencing depression symptoms have a greater vulnerability to infections3 . Also, it has been shown in recent studies that there is a correlation between irregular cytokine levels and an uncontrolled inflammatory response4 . Objective: The present review addresses the relationship between the immune system response and depression. In addition t
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Oliveria, John Paul, Abbey Torek, Tara Strinich, Karen Howie, John Bienenstock, and Gail Gauvreau. "The Hypothalamic-Pituitary-Adrenal Axis In Subjects With Allergic Asthma." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a5650.

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Rigatos, Gerasimos. "Differential flatness properties and adaptive control of the hypothalamic-pituitary-adrenal axis model." In INTERNATIONAL CONFERENCE OF COMPUTATIONAL METHODS IN SCIENCES AND ENGINEERING 2016 (ICCMSE 2016). Author(s), 2016. http://dx.doi.org/10.1063/1.4968674.

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Kolesnikova, M. M., K. A. Ayriyant, E. V. Mezhlumyan, and N. P. Bondar. "INFLUENCE OF EARLY POSTNATAL INFLAMMATION ON GLIAL CELLS AND HYPOTHALAMIC-PITITUITARY-ADRENAL AXIS IN BTBR MALES." In XI МЕЖДУНАРОДНАЯ КОНФЕРЕНЦИЯ МОЛОДЫХ УЧЕНЫХ: БИОИНФОРМАТИКОВ, БИОТЕХНОЛОГОВ, БИОФИЗИКОВ, ВИРУСОЛОГОВ, МОЛЕКУЛЯРНЫХ БИОЛОГОВ И СПЕЦИАЛИСТОВ ФУНДАМЕНТАЛЬНОЙ МЕДИЦИНЫ. IPC NSU, 2024. https://doi.org/10.25205/978-5-4437-1691-6-244.

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BTBR T+Itpr3tf/J (BTBR) mice are a valid model for studying idiopathic autism. This work examines the ability of the experience of induced early postnatal inflammation to enhance neuroinflammation and aberrant functioning of the hypothalamic-pituitary-adrenal axis observed in both patients with autism and BTBR mice.
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Chakrabarty, Ankush, Gregery T. Buzzard, Martin J. Corless, Stanislaw H. Zak, and Ann E. Rundell. "Correcting hypothalamic-pituitary-adrenal axis dysfunction using observer-based explicit nonlinear model predictive control." In 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2014. http://dx.doi.org/10.1109/embc.2014.6944359.

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Kaslik, Eva, Dan Bogdan Navolan, and Mihaela Neamţu. "Stability analysis of a hypothalamic-pituitary-adrenal axis model with inclusion of glucocorticoid receptor and memory." In ICNPAA 2016 WORLD CONGRESS: 11th International Conference on Mathematical Problems in Engineering, Aerospace and Sciences. Author(s), 2017. http://dx.doi.org/10.1063/1.4972703.

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Patlis, AsiaLuna. "Cellular and molecular effects of weight stigma: The effect of cortisol on hypothalamic neurons in vitro." In 10th Annual International Weight Stigma Conference. Weight Stigma Conference, 2024. https://doi.org/10.31076/2024.p22.

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Weight stigma has been associated with changes to the stress-responsive hypothalamic-pituitary-adrenocortical (HPA) axis. Chronic activation of the HPA axis leads to elevated levels of circulating glucocorticoids such as cortisol. This poster will show a project proposal to study the cellular and molecular effects of cortisol on human arcuate-like hypothalamic neurons in vitro. The arcuate nucleus of the hypothalamus (ARC) is involved in the homeostatic regulation of body weight and feeding. The ARC is home to two important neuronal populations: proopiomelanocortin (POMC) and agouti-related ne
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Perov, S. Yu, and S. A. Askerova. "THE NEUROENDOCRINE SYSTEM RESPONSE OF 2-5 G COMMUNICATION ELECTROMAGNETIC FIELD ANIMAL EXPOSURE." In The 16th «OCCUPATION and HEALTH» Russian National Congress with International Participation (OHRNC-2021). FSBSI “IRIOH”, 2021. http://dx.doi.org/10.31089/978-5-6042929-2-1-2021-1-398-402.

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Abstract: Background. The neuroendocrine effect on the hypothalamus-pituitary-adrenal cortex axis is significant example stressor of electromagnetic exposure for biological object. Aim. The neuroendocrine effect investigation of multi-frequency electromagnetic field laboratory animals’ exposure from 2-5 generations cellular base stations Methods. The neuroendocrine status evaluated by corticosterone and adrenocorticotropic hormone (ACTH) concentrations in blood exposed and sham rats. ACTH and corticosterone rat blood assessed by immunoenzyme method. Results. The results of the multi-frequency
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RAVIZZA, L., R. G. MASERA, P. PROLO, et al. "MODULATION OF NATURAL KILLER (NK) CELL ACTIVITY BY HORMONES OF THE HYPOTHALAMIC-PITUITARY-ADRENAL AXIS IN ANOREXIA NERVOSA." In IX World Congress of Psychiatry. WORLD SCIENTIFIC, 1994. http://dx.doi.org/10.1142/9789814440912_0012.

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JURCĂU, Ramona-Niculina, Ioana-Marieta JURCĂU, and Aurelia GLAVAN. "Rhodiola Rosea, an adaptogen useful in fatigue – from research to practice." In Ştiință și educație: noi abordări și perspective", conferinţă ştiinţifică internaţională. Ion Creangă Pedagogical State University, 2024. https://doi.org/10.46727/c.v1.21-22-03-2024.p394-399.

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Rhodiola Rosea (RR) belongs to those herbs that reported having adaptive properties. Studies have shown that RR can reduce mental fatigue in stressful conditions in life. Due to its adaptogenic properties, RR has been studied for its performance-enhancing capabilities in healthy populations and for its therapeutic properties in a number of clinical researches. RR determines the regulation of homeostasis through several mechanisms of action associated with the hypothalamic pituitary-adrenal axis and the control of key mediators of the stress response, including cortisol. Thus, RR reduces mental
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Reports on the topic "Hypothalamic Pituitary Adrenal Axis (HPA)"

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Vargas-Uricoechea, Hernando, Alejandro Castellanos-Pinedo, Karen Urrego-Noguera, et al. Mindfulness-Based Interventions and the Hypothalamic–Pituitary–Adrenal Axis: A Systematic Review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2024. http://dx.doi.org/10.37766/inplasy2024.11.0017.

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