Log in

Relevant bibliographies by topics / Hypothalmic diseases / Journal articles

To see the other types of publications on this topic, follow the link: Hypothalmic diseases.

Journal articles on the topic 'Hypothalmic diseases'

Author: Grafiati

Published: 27 July 2024

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Hypothalmic diseases.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Haug, R. H. "Recovery of the hypothalmic-pituitary adrenal (HPA) axis in patients with rheumatic diseases receiving low-dose prednisone." Journal of Oral and Maxillofacial Surgery 52, no. 2 (1994): 203. http://dx.doi.org/10.1016/0278-2391(94)90422-7.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Kim, Ye Jin, Thai Hien Tu, Sunggu Yang, Jae Kwang Kim, and Jae Geun Kim. "Characterization of Fatty Acid Composition Underlying Hypothalamic Inflammation in Aged Mice." Molecules 25, no. 14 (2020): 3170. http://dx.doi.org/10.3390/molecules25143170.

Full text

Abstract:

Degenerative diseases, which can develop during aging, are underlined by inflammatory processes. Hypothalamic inflammation triggered by elevation in circulating fatty acid levels is directly coupled to metabolic disorders. The present study aimed to investigate and characterize the hypothalamic inflammation and composition of fatty acids in the hypothalami of aged mice. We verified that inflammation and microglial activation occur in the hypothalami of aged mice by performing quantitative real-time PCR and using immunohistochemistry methods. In addition, we observed increased levels of various

APA, Harvard, Vancouver, ISO, and other styles

3

Zapanti, Evangelia, Konstantinos Terzidis, and George Chrousos. "Dysfunction of the Hypothalamic-Pituitary-Adrenal axis in HIV infection and disease." HORMONES 7, no. 3 (2008): 205–16. http://dx.doi.org/10.14310/horm.2002.1200.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Mravec, Boris, and Alena Szelle Černáčková. "Hypothalamic inflammation and somatic diseases." Česká a slovenská neurologie a neurochirurgie 81/114, no. 3 (2018): 278–83. http://dx.doi.org/10.14735/amcsnn2018278.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

von Werder, K., and O. A. Müller. "Medical therapy of hypothalamic diseases." Acta Neurochirurgica 75, no. 1-4 (1985): 147–51. http://dx.doi.org/10.1007/bf01406335.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Salvio, Gianmaria, Marianna Martino, Giulia Giancola, Giorgio Arnaldi, and Giancarlo Balercia. "Hypothalamic–Pituitary Diseases and Erectile Dysfunction." Journal of Clinical Medicine 10, no. 12 (2021): 2551. http://dx.doi.org/10.3390/jcm10122551.

Full text

Abstract:

Several hormones contribute to ensure penile erection, a neurovascular phenomenon in which nitric oxide plays a major role. Erectile dysfunction (ED), which is defined as the persistent inability to obtain or maintain penile erection sufficient for a satisfactory sexual performance, may be due to arteriogenic, neurogenic, iatrogenic, but also endocrinological causes. The hypothalamus–pituitary axis plays a central role in the endocrine system and represents a fundamental link between the brain and peripheral glands, including gonads. Therefore, the hormonal production of the hypothalamic–pitui

APA, Harvard, Vancouver, ISO, and other styles

7

Swaab, Dick F. "Hypothalamic Peptides in Human Brain Diseases." Trends in Endocrinology & Metabolism 10, no. 6 (1999): 236–44. http://dx.doi.org/10.1016/s1043-2760(99)00158-7.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Reimann, Hobart A. "HYPOTHALAMIC-HYPOPHYSEAL-NEURAL INFLUENCE IN PERIODIC DISEASES." Annals of the New York Academy of Sciences 117, no. 1 (2006): 589–94. http://dx.doi.org/10.1111/j.1749-6632.1964.tb48210.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Lapko, Inna V., Alla V. Zheglova, Kristina V. Klimkina, and Inessa A. Bogatyreva. "Neurohumoral regulation under exposure to vibration and physical overloads." Hygiene and sanitation 101, no. 10 (2022): 1200–1205. http://dx.doi.org/10.47470/0016-9900-2022-101-10-1200-1205.

Full text

Abstract:

Introduction. In response to the action of various occupational factors, central regulatory mechanisms, including the hypothalamus, are involved. Clarification of the influence of the hypothalamus on the indicators of peripheral blood circulation, peripheral innervation and bone metabolism under the influence of vibration and physical overloads is relevant for the diagnosis and treatment of occupational diseases of a neurological profile. The aim of the study. To establish the relationship between hypothalamic disorders and functional indicators of occupational diseases of the peripheral nervo

APA, Harvard, Vancouver, ISO, and other styles

10

Stathori, Galateia, Kyriaki Hatziagapiou, George Mastorakos, Nikolaos F. Vlahos, Evangelia Charmandari, and Georgios Valsamakis. "Endocrine-Disrupting Chemicals, Hypothalamic Inflammation and Reproductive Outcomes: A Review of the Literature." International Journal of Molecular Sciences 25, no. 21 (2024): 11344. http://dx.doi.org/10.3390/ijms252111344.

Full text

Abstract:

Endocrine-disrupting chemicals (EDCs) are environmental and industrial agents that interfere with hormonal functions. EDC exposure is linked to various endocrine diseases, especially in reproduction, although the mechanisms remain unclear and effects vary among individuals. Neuroinflammation, particularly hypothalamic inflammation, is an emerging research area with implications for endocrine-related diseases like obesity. The hypothalamus plays a crucial role in regulating reproduction, and its inflammation can adversely affect reproductive health. EDCs can cross the blood–brain barrier, poten

APA, Harvard, Vancouver, ISO, and other styles

11

Mravec, Boris, Lubica Horvathova, and Alena Cernackova. "Hypothalamic Inflammation at a Crossroad of Somatic Diseases." Cellular and Molecular Neurobiology 39, no. 1 (2018): 11–29. http://dx.doi.org/10.1007/s10571-018-0631-4.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Cai, Dongsheng, and Sinan Khor. "“Hypothalamic Microinflammation” Paradigm in Aging and Metabolic Diseases." Cell Metabolism 30, no. 1 (2019): 19–35. http://dx.doi.org/10.1016/j.cmet.2019.05.021.

Full text

APA, Harvard, Vancouver, ISO, and other styles

13

Karagiannis, Asterios, and Faidon Harsoulis. "Gonadal dysfunction in systemic diseases." European Journal of Endocrinology 152, no. 4 (2005): 501–13. http://dx.doi.org/10.1530/eje.1.01886.

Full text

Abstract:

Gonadal function is significantly affected in many acute and chronic systemic diseases. As the function of the testes and the ovaries is determined by the integrity of the hypothalamic–pituitary–gonadal axis, it is obvious that a systemic disease may affect one or more levels of the axis in such a manner that the gonadal dysfunction may have various clinical and laboratory manifestations. In this brief review, the most common disturbances seen in the main systemic diseases will be discussed.

APA, Harvard, Vancouver, ISO, and other styles

14

Rychlik, A., M. Nowicki, A. Kolodziejska-Sawerska, and M. Szweda. "The effect of orally administered Budesonide on the hypothalamic-pituitary-adrenal axis in dogs with inflammatory bowel disease." Veterinární Medicína 62, No. 5 (2017): 261–68. http://dx.doi.org/10.17221/130/2015-vetmed.

Full text

Abstract:

The aim of this study was to evaluate the effect of Budesonide on the hypothalamic-pituitary-adrenal (HPA) axis in dogs with inflammatory bowel disease. The effect of orally administered Budesonide (Entocort) on the HPA axis was analysed in 21 dogs with inflammatory bowel disease. Biochemical analyses were carried out to evaluate the activity levels of alanine aminotransferase, asparagine aminotransferase, alkaline phosphatase, cortisol and endogenous adrenocorticotropic hormone. Urine samples were collected from each patient before the study and after 30 days of the experiment to determine th

APA, Harvard, Vancouver, ISO, and other styles

15

Plakkot, Bhuvana, Ashley Di Agostino, and Madhan Subramanian. "Implications of Hypothalamic Neural Stem Cells on Aging and Obesity-Associated Cardiovascular Diseases." Cells 12, no. 5 (2023): 769. http://dx.doi.org/10.3390/cells12050769.

Full text

Abstract:

The hypothalamus, one of the major regulatory centers in the brain, controls various homeostatic processes, and hypothalamic neural stem cells (htNSCs) have been observed to interfere with hypothalamic mechanisms regulating aging. NSCs play a pivotal role in the repair and regeneration of brain cells during neurodegenerative diseases and rejuvenate the brain tissue microenvironment. The hypothalamus was recently observed to be involved in neuroinflammation mediated by cellular senescence. Cellular senescence, or systemic aging, is characterized by a progressive irreversible state of cell cycle

APA, Harvard, Vancouver, ISO, and other styles

16

Cai, Dongsheng, and Tiewen Liu. "Hypothalamic inflammation: a double-edged sword to nutritional diseases." Annals of the New York Academy of Sciences 1243, no. 1 (2011): E1—E39. http://dx.doi.org/10.1111/j.1749-6632.2011.06388.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Djordjevic, Ana, Nataša Veličković, Biljana Bursać, Ana Teofilović, and Gordana Matić. "The role of glucocorticoid hormones in diet-induced metabolic diseases." Biologia Serbica 39, no. 1 (2017): 16–25. https://doi.org/10.5281/zenodo.826607.

Full text

Abstract:

<strong>Summary.</strong> Excessive fructose intake promotes the development of metabolic syndrome through the deregulation of metabolic pathways in the hypothalamus, liver and adipose tissue, which play crucial roles in metabolic homeostasis by responding to the body’s nutritional and energy requirements. Variable amounts and modes of fructose intake have been shown to result in different patterns of expression of metabolic disturbances, which generally include adiposity, insulin and leptin resistance, dyslipidemia and hypertension. We explored the possible mediatory role of glucocorticoid si

APA, Harvard, Vancouver, ISO, and other styles

18

Kurup, R. K., and P. A. Kurup. "Hypothalamic digoxin and brain function." Acta Neuropsychiatrica 15, no. 2 (2003): 74–90. http://dx.doi.org/10.1034/j.1601-5215.2003.00012.x.

Full text

Abstract:

Background and objectives:The study assessed the biochemical differences between right hemispheric-dominant and left hemispheric-dominant individuals. The chemical hemispheric-dominance in various systemic and neuropsychiatric diseases was also studied.Methods:The isoprenoid metabolites, digoxin, dolichol and ubiquinone, glycoconjugate metabolism, free radical metabolism and the RBC membrane composition, were studied in individuals with differing hemispheric-dominance. The digoxin levels and RBC membrane Na+-K+ATPase activity were also studied in systemic and neuropsychiatric diseases.Results:

APA, Harvard, Vancouver, ISO, and other styles

19

Müller, Hermann L. "RARE-04. Hypothalamic syndrome – severe sequelae due to different sellar and parasellar masses." Neuro-Oncology 24, Supplement_1 (2022): i9—i10. http://dx.doi.org/10.1093/neuonc/noac079.029.

Full text

Abstract:

Abstract Hypothalamic syndrome is a rare disorder caused by disease- and/or treatment-related injury to the hypothalamus, most commonly associated with rare, noncancerous parasellar masses such as craniopharyngioma, germ cell tumours, gliomas, cysts of Rathke’s pouch and Langerhans cell histiocytosis as well as genetic neurodevelopmental syndromes such as Prader-Willi syndrome and septo-optic dysplasia. Hypothalamic syndrome is characterized by intractable weight gain associated with severe morbid obesity and memory impairment, attention deficit, reduced impulse control as well as increased ri

APA, Harvard, Vancouver, ISO, and other styles

20

KURUP, RAVI KUMAR, and PARAMESWARA ACHUTHA KURUP. "HYPOTHALAMIC DIGOXIN, CEREBRAL CHEMICAL DOMINANCE, AND PATHOGENESIS OF PULMONARY DISEASES." International Journal of Neuroscience 113, no. 2 (2003): 235–58. http://dx.doi.org/10.1080/00207450390162056.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

ABRAMSKY, O., E. WERTMAN, A. RECHES, T. BRENNER, and H. OVADIA. "Effect of Hypothalamic Lesions on Experimental Autoimmune Diseases in Rats." Annals of the New York Academy of Sciences 496, no. 1 Neuroimmune I (1987): 360–65. http://dx.doi.org/10.1111/j.1749-6632.1987.tb35788.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Ulisse, Salvatore, Enke Baldini, Daniele Pironi, et al. "Is Melanoma Progression Affected by Thyroid Diseases?" International Journal of Molecular Sciences 23, no. 17 (2022): 10036. http://dx.doi.org/10.3390/ijms231710036.

Full text

Abstract:

Clinical and epidemiological evidence indicate a relationship between thyroid diseases and melanoma. In particular, the hypothyroidism condition appears to promote melanoma spread, which suggests a protective role of thyroid hormones against disease progression. In addition, experimental data suggest that, in addition to thyroid hormones, other hormonal players of the hypothalamic–pituitary–thyroid (HPT) axis, namely the thyrotropin releasing hormone and the thyrotropin, are likely to affect melanoma cells behavior. This information warrants further clinical and experimental studies in order t

APA, Harvard, Vancouver, ISO, and other styles

23

Thomaz, Natalie K., Larissa Daniele Bobermin, and André Quincozes-Santos. "Sexual Dimorphism and Hypothalamic Astrocytes: Focus on Glioprotection." Neuroglia 5, no. 3 (2024): 274–88. http://dx.doi.org/10.3390/neuroglia5030019.

Full text

Abstract:

Sexual dimorphism refers to biological differences between males and females in the same species, including morphological, physiological, and behavioral characteristics. Steroid hormones are associated with changes in several brain regions, as well as the pathophysiology of aging, obesity, and neuropsychiatric diseases. The hypothalamus controls several physiological processes, including metabolism, reproduction, circadian rhythm, and body homeostasis. Refined communication between neurons and glial cells, particularly astrocytes, coordinates physiological and behavioral hypothalamic functions

APA, Harvard, Vancouver, ISO, and other styles

24

Melnichenko, G. A., V. A. Chernogolov, and M. G. Pavlova. "General data on the hypothalamic-pituitary disorders (guidelines for patients)." Problems of Endocrinology 42, no. 4 (1996): 31–32. http://dx.doi.org/10.14341/probl12072.

Full text

Abstract:

Most diseases of the hypothalamus and pituitary gland are relatively rare, and therefore not only patients, but many doctors are new to their manifestations, diagnostic methods, treatment tactics, and most importantly, rehabilitation methods (including psychological). The low incidence of such diseases, however, does not detract from the importance of the problems faced by a particular patient. Currently, schools for teaching methods of self-monitoring of patients with diabetes mellitus and a number of other chronic diseases have been created and are actively functioning. There is a need to cr

APA, Harvard, Vancouver, ISO, and other styles

25

Noraliev, I.A. "THE ROLE OF DEPRESSION IN THE DEVELOPMENT OF CARDIOVASCULAR DISEASES." Multidisciplinary Journal of Science and Technology 5, no. 5 (2025): 830–32. https://doi.org/10.5281/zenodo.15465028.

Full text

Abstract:

This article explores the intricate relationship between depression and cardiovascular diseases (CVDs), examining how psychological distress, particularly major depressive disorder (MDD), contributes to the onset, progression, and prognosis of various heart-related conditions. It reviews the biological, behavioral, and social pathways through which depression exerts its influence, including dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, increased inflammatory markers, poor health behaviors, and medication non-adherence. The growing body of evidence underscores the importance o

APA, Harvard, Vancouver, ISO, and other styles

26

Mukhopadhyay, Debasmita, and Bashair M. Mussa. "Identification of Novel Hypothalamic MicroRNAs as Promising Therapeutics for SARS-CoV-2 by Regulating ACE2 and TMPRSS2 Expression: An In Silico Analysis." Brain Sciences 10, no. 10 (2020): 666. http://dx.doi.org/10.3390/brainsci10100666.

Full text

Abstract:

Background: Neuroinvasion of severe acute respiratory syndrome coronavirus (SARS-CoV) is well documented and, given the similarities between this virus and SARS-CoV-2, it seems that the neurological impairment that is associated with coronavirus disease 2019 (COVID-19) is due to SARS-CoV-2 neuroinvasion. Hypothalamic circuits are exposed to the entry of the virus via the olfactory bulb and interact centrally with crucial respiratory nuclei. Hypothalamic microRNAs are considered as potential biomarkers and modulators for various diseases and future therapeutic targets. The present study aims to

APA, Harvard, Vancouver, ISO, and other styles

27

Vorontsov, A. V., T. V. Semicheva, and V. A. Peterkova. "Magnetic resonance imaging in the diagnosis of hypothalamopituitary diseases in patients with true premature sexual development." Problems of Endocrinology 49, no. 1 (2003): 32–36. http://dx.doi.org/10.14341/probl11438.

Full text

Abstract:

То evaluate the incidence of different types of organic abnormalities occurring in premature sexual development (PSD) of central genesis and to study a role of magnetic resonance imaging (MRI) in the diagnosis of PSD, MRI was used in 33 patients with a clinically established diagnosis of true (gonadotropin-dependent) PSD of central genesis. Among the examined children with PSD, hypothalamic hamartoma was detected in 27.3%) of the patients; there were no MRI data suggesting hypothalamopituitary abnormalities in 72.7%o. On the MRI images, a hypothalamic hamartoma appeared as a round or oval

APA, Harvard, Vancouver, ISO, and other styles

28

Schaefer, S., N. Boegershausen, S. Meyer, D. Ivan, K. Schepelmann, and P. H. Kann. "Hypothalamic–pituitary insufficiency following infectious diseases of the central nervous system." European Journal of Endocrinology 158, no. 1 (2008): 3–9. http://dx.doi.org/10.1530/eje-07-0484.

Full text

Abstract:

ObjectiveHypothalamic–pituitary insufficiency may have diverse causes. The aim of this study was to determine the incidence of hypothalamic–pituitary insufficiency in patients with previous infectious diseases of the central nervous system (CNS) of different etiologies and mild-to-moderate clinical course.DesignPatient series. Basal and stimulated (insulin tolerance test) pituitary function testing was performed in 19 patients with previous neuroborreliosis, encephalitis, or meningitis following an interval of between 10 and 56 months (mean 26.1±13.1 months) after the acute event.ResultsFour p

APA, Harvard, Vancouver, ISO, and other styles

29

Crofford, Leslie J. "The hypothalamic–pituitary–adrenal axis in the pathogenesis of rheumatic diseases." Endocrinology and Metabolism Clinics of North America 31, no. 1 (2002): 1–13. http://dx.doi.org/10.1016/s0889-8529(01)00004-4.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

HARBUZ, M. S., D. S. JESSOP, H. S. CHOWDREY, J. M. BLACKWELL, P. J. LARSEN, and S. L. LIGHTMAN. "Evidence for Altered Control of Hypothalamic CRF in Immune-Mediated Diseases." Annals of the New York Academy of Sciences 771, no. 1 Stress (1995): 449–58. http://dx.doi.org/10.1111/j.1749-6632.1995.tb44701.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Lee, Hannah, Thai Hien Tu, Byong Seo Park, Sunggu Yang, and Jae Geun Kim. "Adiponectin Reverses the Hypothalamic Microglial Inflammation during Short-Term Exposure to Fat-Rich Diet." International Journal of Molecular Sciences 20, no. 22 (2019): 5738. http://dx.doi.org/10.3390/ijms20225738.

Full text

Abstract:

Adiponectin, an adipokine derived from the adipose tissue, manifests anti-inflammatory effects in the metabolically active organs and is, therefore, beneficial in various metabolic diseases associated with inflammation. However, the role of adiponectin in alleviating the hypothalamic inflammation connected to the pathogenesis of obesity has not yet been clearly interrogated. Here, we identified that the systemic administration of adiponectin suppresses the activation of microglia and thereby reverses the hypothalamic inflammation during short-term exposure to a high-fat diet. Additionally, we

APA, Harvard, Vancouver, ISO, and other styles

32

Lencu, Codruţa, Teodora Alexescu, Mirela Petrulea, and Monica Lencu. "RESPIRATORY MANIFESTATIONS IN ENDOCRINE DISEASES." Medicine and Pharmacy Reports 89, no. 4 (2016): 459–63. http://dx.doi.org/10.15386/cjmed-671.

Full text

Abstract:

The control mechanisms of respiration as a vital function are complex: voluntary – cortical, and involuntary – metabolic, neural, emotional and endocrine. Hormones and hypothalamic neuropeptides (that act as neurotrasmitters and neuromodulators in the central nervous system) play a role in the regulation of respiration and in bronchopulmonary morphology. This article presents respiratory manifestations in adult endocrine diseases that evolve with hormone deficit or hypersecretion. In hyperthyroidism, patients develop ventilation disorders, obstructive and central sleep apnea, and pleural colle

APA, Harvard, Vancouver, ISO, and other styles

33

Kõks, Sulev, Ursel Soomets, Mario Plaas, et al. "Hypothalamic gene expression profile indicates a reduction in G protein signaling in the Wfs1 mutant mice." Physiological Genomics 43, no. 24 (2011): 1351–58. http://dx.doi.org/10.1152/physiolgenomics.00117.2011.

Full text

Abstract:

The Wfs1 gene codes for a protein with unknown function, but deficiency in this protein results in a range of neuropsychiatric and neuroendocrine syndromes. In the present study we aimed to find the functional networks influenced by Wfs1 in the hypothalamus. We performed gene expression profiling (Mouse Gene 1.0 ST Arrays) in Wfs1-deficient mice; 305 genes were differentially expressed with nominal P value < 0.01. FDR (false discovery rate)-adjusted P values were significant (0.007) only for two genes: C4b (t=9.66) and Wfs1 ( t = −9.03). However, several genes related to G protein signaling

APA, Harvard, Vancouver, ISO, and other styles

34

Ryzhov, J. R., and A. O. Shpakov. "ADIPONECTIN AS AN ENDOGENOUS REGULATOR OF THE HYPOTHALAMIC-PITUITARY-GONADAL AXIS." Translational Medicine 5, no. 5 (2018): 26–36. http://dx.doi.org/10.18705/2311-4495-2018-5-5-.

Full text

Abstract:

Adiponectin is the most important adipokine controlling the food behavior and energy homeostasis. At present, there is much evidence that adiponectin also regulates the functions of the reproductive system, and its targets are hypothalamic neurons responsible for the synthesis and secretion of gonadoliberin, the pituitary gonadotrophs producing the luteinizing hormone, and the gonads. In the target tissues, which are blocks of the hypothalamic-pituitary-gonadal axis, all the main components of adiponectin-regulated signaling system, including adiponectin and both types of adiponectin receptors

APA, Harvard, Vancouver, ISO, and other styles

35

Ryzhov, J. R., and A. O. Shpakov. "ADIPONECTIN AS AN ENDOGENOUS REGULATOR OF THE HYPOTHALAMIC-PITUITARY-GONADAL AXIS." Translational Medicine 5, no. 5 (2018): 26–36. http://dx.doi.org/10.18705/2311-4495-2018-5-5-26-36.

Full text

Abstract:

Adiponectin is the most important adipokine controlling the food behavior and energy homeostasis. At present, there is much evidence that adiponectin also regulates the functions of the reproductive system, and its targets are hypothalamic neurons responsible for the synthesis and secretion of gonadoliberin, the pituitary gonadotrophs producing the luteinizing hormone, and the gonads. In the target tissues, which are blocks of the hypothalamic-pituitary-gonadal axis, all the main components of adiponectin-regulated signaling system, including adiponectin and both types of adiponectin receptors

APA, Harvard, Vancouver, ISO, and other styles

36

Park, Joon Seok, Kyu Sik Kim, and Hyung Jin Choi. "Glucagon-Like Peptide-1 and Hypothalamic Regulation of Satiation: Cognitive and Neural Insights from Human and Animal Studies." Diabetes & Metabolism Journal 49, no. 3 (2025): 333–47. https://doi.org/10.4093/dmj.2025.0106.

Full text

Abstract:

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have emerged as blockbuster drugs for treating metabolic diseases. Glucagon-like peptide-1 (GLP-1) plays a pivotal role in glucose homeostasis by enhancing insulin secretion, suppressing glucagon release, delaying gastric emptying, and acting on the central nervous system to regulate satiation and satiety. This review summarizes the discovery of GLP-1 and the development of GLP-1RAs, with a particular focus on their central mechanisms of action. Human neuroimaging studies demonstrate that GLP-1RAs influence brain activity during food cogniti

APA, Harvard, Vancouver, ISO, and other styles

37

Van Drunen, Rachel, and Kristin Eckel-Mahan. "Circadian Rhythms of the Hypothalamus: From Function to Physiology." Clocks & Sleep 3, no. 1 (2021): 189–226. http://dx.doi.org/10.3390/clockssleep3010012.

Full text

Abstract:

The nearly ubiquitous expression of endogenous 24 h oscillations known as circadian rhythms regulate the timing of physiological functions in the body. These intrinsic rhythms are sensitive to external cues, known as zeitgebers, which entrain the internal biological processes to the daily environmental changes in light, temperature, and food availability. Light directly entrains the master clock, the suprachiasmatic nucleus (SCN) which lies in the hypothalamus of the brain and is responsible for synchronizing internal rhythms. However, recent evidence underscores the importance of other hypoth

APA, Harvard, Vancouver, ISO, and other styles

38

Hosseinifard, Elaheh-Sadat, Khadijeh Bavafa-Valenlia, Maryam Saghafi-Asl, and Mohammad Morshedi. "Antioxidative and Metabolic Effects of Lactobacillus plantarum, Inulin, and Their Synbiotic on the Hypothalamus and Serum of Healthy Rats." Nutrition and Metabolic Insights 13 (January 2020): 117863882092509. http://dx.doi.org/10.1177/1178638820925092.

Full text

Abstract:

Nowadays, much attention has been paid to the link between gut microbiota and brain. The beneficial metabolic effects of probiotics and prebiotics in several diseases such as diabetes and obesity have been reported. However, studies bridging the association of gut microbiome with brain function in healthy states are rare. Therefore, it was hypothesized that the administration of Lactobacillus plantarum ( L plantarum) and inulin may affect serum and hypothalamic metabolic parameters as well as oxidative markers in healthy male rats. Daily L plantarum (107 CFU/mL) and inulin (5% of daily food we

APA, Harvard, Vancouver, ISO, and other styles

39

Laviano, Alessandro, Akio Inui, Daniel L. Marks, et al. "Neural control of the anorexia-cachexia syndrome." American Journal of Physiology-Endocrinology and Metabolism 295, no. 5 (2008): E1000—E1008. http://dx.doi.org/10.1152/ajpendo.90252.2008.

Full text

Abstract:

The anorexia-cachexia syndrome is a debilitating clinical condition characterizing the course of chronic diseases, which heavily impacts on patients' morbidity and quality of life, ultimately accelerating death. The pathogenesis is multifactorial and reflects the complexity and redundancy of the mechanisms controlling energy homeostasis under physiological conditions. Accumulating evidence indicates that, during disease, disturbances of the hypothalamic pathways controlling energy homeostasis occur, leading to profound metabolic changes in peripheral tissues. In particular, the hypothalamic me

APA, Harvard, Vancouver, ISO, and other styles

40

Panaro, Maria Antonietta, Tarek Benameur, and Chiara Porro. "Hypothalamic Neuropeptide Brain Protection: Focus on Oxytocin." Journal of Clinical Medicine 9, no. 5 (2020): 1534. http://dx.doi.org/10.3390/jcm9051534.

Full text

Abstract:

Oxytocin (OXT) is hypothalamic neuropeptide synthetized in the brain by magnocellular and parvo cellular neurons of the paraventricular (PVN), supraoptic (SON) and accessory nuclei (AN) of the hypothalamus. OXT acts in the central and peripheral nervous systems via G-protein-coupled receptors. The classical physiological functions of OXT are uterine contractions, the milk ejection reflex during lactation, penile erection and sexual arousal, but recent studies have demonstrated that OXT may have anti-inflammatory and anti-oxidant properties and regulate immune and anti-inflammatory responses. I

APA, Harvard, Vancouver, ISO, and other styles

41

Chiurazzi, Martina, Martina Di Maro, Mauro Cozzolino, and Antonio Colantuoni. "Mitochondrial Dynamics and Microglia as New Targets in Metabolism Regulation." International Journal of Molecular Sciences 21, no. 10 (2020): 3450. http://dx.doi.org/10.3390/ijms21103450.

Full text

Abstract:

Energy homeostasis regulation is essential for the maintenance of life. Neuronal hypothalamic populations are involved in the regulation of energy balance. In order play this role, they require energy: mitochondria, indeed, have a key role in ensuring a constant energy supply to neurons. Mitochondria are cellular organelles that are involved in dynamic processes; their dysfunction has been associated with many diseases, such as obesity and type 2 diabetes, indicating their importance in cellular metabolism and bioenergetics. Food intake excess can induce mitochondrial dysfunction with conseque

APA, Harvard, Vancouver, ISO, and other styles

42

KAUPPILA, MARJUT, PERTTI KOSKINEN, KARI REMES, JORMA VIIKARI та KERTTU IRJALA. "Hypothalamic-Pituitary Axis Remains Intact After Interferon-α Treatment in Hematologic Diseases". Journal of Interferon & Cytokine Research 17, № 9 (1997): 543–50. http://dx.doi.org/10.1089/jir.1997.17.543.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Sabirova, E. Y., and E. N. Anisimova. "AGING AND CIRCADIAN RHYTHM DISORDERS: CURRENT STATE OF THE ISSUE." DRUGS AND RATIONAL PHARMACOTHERAPY 11, no. 2 (2024): 32–36. http://dx.doi.org/10.56356/27827259_2023_11_32.

Full text

Abstract:

Over the last century, the number of diseases associated with age, such as type 2 diabetes mellitus, obesity, mental illness, and a number of oncological pathologies, has increased significantly, which has a negative impact on the overall quality of life. Studies in aged animal models have revealed progressive dyscoordination at multiple levels of regulation, including transcriptional, translational, and posttranslational processes, as a result of cellular stress and circadian disruption. The circadian clock is emerging as a key regulator maintaining physiological homeostasis and promoting hea

APA, Harvard, Vancouver, ISO, and other styles

44

Salahuddin, Mohammed F., Fakhri Mahdi, Suresh P. Sulochana, and Jason J. Paris. "HIV-1 Tat Protein Promotes Neuroendocrine Dysfunction Concurrent with the Potentiation of Oxycodone’s Psychomotor Effects in Female Mice." Viruses 13, no. 5 (2021): 813. http://dx.doi.org/10.3390/v13050813.

Full text

Abstract:

Human immunodeficiency virus (HIV) is associated with neuroendocrine dysfunction which may contribute to co-morbid stress-sensitive disorders. The hypothalamic-pituitary-adrenal (HPA) or -gonadal (HPG) axes are perturbed in up to 50% of HIV patients. The mechanisms are not known, but we have found the HIV-1 trans-activator of transcription (Tat) protein to recapitulate the clinical phenotype in male mice. We hypothesized that HPA and/or HPG dysregulation contributes to Tat-mediated interactions with oxycodone, an opioid often prescribed to HIV patients, in females. Female mice that conditional

APA, Harvard, Vancouver, ISO, and other styles

45

Zenkova, T. S., and I. A. Fedin. "The use of magnetic resonance imaging in the diagnosis of diseases of the hypothalamic-pituitary system." Problems of Endocrinology 39, no. 6 (1993): 57–62. http://dx.doi.org/10.14341/probl11955.

Full text

Abstract:

In recent years, it has become apparent that the incidence of diseases of the hypothalamic-pituitary system is extremely high. The clinical manifestations of diseases such as acromegaly, Itsenko Cushing's disease, primary hyperprolactinemic hypogonadism are considered to be well known [8, 9, 32, 45]. However, to select the optimal method of treatment in each specific clinical situation, it is imperative for the clinician to obtain information about the state of the main structural link of the pathological process - the pituitary gland

APA, Harvard, Vancouver, ISO, and other styles

46

Molfino, Alessio, Gianfranco Gioia, Filippo Rossi Fanelli, and Alessandro Laviano. "Contribution of Neuroinflammation to the Pathogenesis of Cancer Cachexia." Mediators of Inflammation 2015 (2015): 1–7. http://dx.doi.org/10.1155/2015/801685.

Full text

Abstract:

Inflammation characterizes the course of acute and chronic diseases and is largely responsible for the metabolic and behavioral changes occurring during the clinical journey of patients. Robust data indicate that, during cancer, functional modifications within brain areas regulating energy homeostasis contribute to the onset of anorexia, reduced food intake, and increased catabolism of muscle mass and adipose tissue. In particular, functional changes are associated with increased hypothalamic concentration of proinflammatory cytokines, which suggests that neuroinflammation may represent the ad

APA, Harvard, Vancouver, ISO, and other styles

47

Gilyazutdinov, I. A., M. K. Mikhailov, and F. Z. Mindubaeva. "Importance of craniography in the diagnosis of neuroendocrinal syndromes and central genesis diseases." Kazan medical journal 74, no. 4 (1993): 288–90. http://dx.doi.org/10.17816/kazmj71446.

Full text

Abstract:

As many as 681 patients with syndromes of scleropolycystosis of ovaries, amenorrhea, galactorrhea, oligonorrhea, lutein phase deficiency, climacteric, hypothalamic genesis obesity and sterility, precancer and cancer of endometrium, and body of the womb are observed. Calcium metabolism is examined in some patients. The frequency of the changes of bones of the vault and base of the skull in the above mentioned states (signs of endocraniosis, en docrinopathy, intracranial hypertension as well as calcification of the pineal gland) is given,, It is stated that patients with ncuroendocrii. Syndromes

APA, Harvard, Vancouver, ISO, and other styles

48

Makovka, Yu V., L. A. Fedoseeva, D. Yu Oshchepkov, A. L. Markel, and O. E. Redina. "Restraint stress-induced expression of <i>Fos</i> and several related genes in the hypothalamus of the hypertensive ISIAH rats." Молекулярная биология 58, no. 1 (2024): 78–87. http://dx.doi.org/10.31857/s0026898424010079.

Full text

Abstract:

Stress can play a significant role in the development of arterial hypertension and many other complications of cardiovascular diseases. Considerable attention is paid to the study of the molecular mechanisms involved in the body’s response to stressful influences, but there are still many blank spots in understanding the details. ISIAH rats model a stress-sensitive form of arterial hypertension. ISIAH rats are characterized by genetically determined enhanced hypothalamic-adrenal-cortical and sympathetic adrenomedullary systems activity, which suggests a functional state of increased stress rea

APA, Harvard, Vancouver, ISO, and other styles

49

Pigarova, E. A., L. K. Dzeranova, and L. Ya Rozhinskaya. "Klinicheskiy sluchay narusheniyavodno-elektrolitnogo obmena kak pervogosimptoma rasprostranennogo metastaticheskogoprotsessa: osobennosti diagnostiki i lecheniyapreparatom sinteticheskogo analogavazopressina (Presayneks)." Obesity and metabolism 8, no. 3 (2011): 67–70. http://dx.doi.org/10.14341/2071-8713-4840.

Full text

Abstract:

The main manifestations of central diabetes insipidus (CDI), a disease of absolute deficiency of hypothalamic hormone vasopressin, are severe thirst and polyuria, which severely interferes with normal life of patients. In some cases CDI may be the first sign of wide spread metastatic process, appearing many years after successful treatment of oncological diseases.

APA, Harvard, Vancouver, ISO, and other styles

50

Muir, Andrew, and Noel K. Maclaren. "Autoimmune Diseases of the Adrenal Glands, Parathyroid Glands, Gonads, and Hypothalamic-Pituitary Axis." Endocrinology and Metabolism Clinics of North America 20, no. 3 (1991): 619–44. http://dx.doi.org/10.1016/s0889-8529(18)30261-5.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!