Academic literature on the topic 'Hypoxic-ischemic CNS'

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Journal articles on the topic "Hypoxic-ischemic CNS"

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Sorokovikova, T. V., L. V. Chichanovskaya, T. V. Menshikova, et al. "Current concepts of hypoxic-ischemic CNS lesions." Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery), no. 6 (May 28, 2025): 742–51. https://doi.org/10.33920/med-01-2506-04.

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Hypoxic-ischemic lesions occur in premature and preterm infants and lead to disorders of the central nervous system, with the main cause of this condition being perinatal asphyxia. Modern statistical data indicate that approximately every second newborn with systemic hypoxia in the perinatal period has morphofunctional CNS disorders. Currently, asphyxia is the third most common cause of neonatal mortality, with prematurity and severe infectious diseases ranking first and second. Hypoxic-ischemic encephalopathy occurring in the neonatal period causes abnormalities in the development of the nerv
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Abdullayeva, G., S. Batyrkhanov, and M. Abdullaeva. "Indicators of psychomotor development of premature infants by perinatal CNS lesion." European Psychiatry 64, S1 (2021): S757. http://dx.doi.org/10.1192/j.eurpsy.2021.2006.

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IntroductionThe birth premature babies with hypoxic-ischemic damage to the neutral system with the subsequent development of hypoxic encephalopathy (HIE). Monitoring of the mental development and neurological status of such prematurely born children is carried out taking into account the corrected age and traditional scales.ObjectivesTo compare indicators of psychomotor development in preterm infants (gestational age < 32 weeks) with and without hypoxic-ischemic encephalopathy.MethodsA prospective study was carried out in the neurological department. The study included data from infants wit
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Kravchenko, L. V., M. A. Levkovich, S. B. Berezhanskaya, et al. "Clinical and immunological criteria for prediction of thechronic course of cytomegalovirus infection on the background of hypoxic-ischemic damage of the central nervous system in children in the first year of life." HIV Infection and Immunosuppressive Disorders 14, no. 3 (2022): 35–42. http://dx.doi.org/10.22328/2077-9828-2022-14-3-35-42.

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Objective. To develop prognostic criteria for the chronic course of cytomegalovirus infection by studying disorders of the regulation of the immune response in children of the first year of life against the background of hypoxic-ischemic CNS damage.Materials and methods. 108 newborns with cytomegalovirus infection occurring against the background of perinatal hypoxicischemic lesions of the central unequal system were examined. All observed patients at 1 and 3 months of life conducted an immunological examination, including the determination of T and B-lymphocytes. Determination of the populati
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Saidovich, Ergashev Suxrob, Mamurova Mavludaxon Mirxamzayevna, and Turayev Bobir Temirpulotovich. "CLINICAL-NEUROPHYSIOLOGICAL AND MORPHOLOGICAL STUDIES OF CHILDREN WITH CONSEQUENCES OF HYPOXIC." Journal of Medical Genetics and Clinical Biology 2, no. 2 (2025): 117–25. https://doi.org/10.61796/jmgcb.v2i2.1214.

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Objective: The problem of perinatal brain injury of hypoxic-ischemic genesis remains a critical issue, with a focus on its high mortality rates, significant disability, and impact on neuropsychic and somatic development in children. These injuries lead to difficulties in social adaptation, diagnosis, and treatment. Methods: The study aims to explore current therapeutic measures applied to children with perinatal hypoxic-ischemic damage to the central nervous system (CNS), evaluating their effectiveness in addressing these challenges. Various medical and social factors are examined to understan
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Aleksandrov, A. G., and D. V. Blinov. "Blood-brain barrier breach after acute cerebral hypoxia in infants." Rehabilitology 2, no. 1 (2024): 107–14. http://dx.doi.org/10.17749/2949-5873/rehabil.2024.13.

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Background. Neuronal lesion, including hypoxic-ischemic damage to the central nervous system (CNS) in perinatal period, leads to the release of neuron-specific enolase (NSE) into peripheral bloodstream. Consequently, NSE can be considered as a biological marker of nervous system injury. Based on NSE level analysis, timely rehabilitation for newborns can be provided, thereby reducing the likelihood of complications associated with CNS injury.Objective: retrospective assessment of NSE level in peripheral blood over a 24-week period in infants of different gestational age with perinatal hypoxic-i
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Petrashenko, Viktoria A., Andrii M. Loboda, Olexandr I. Smiyan, et al. "LABORATORY CRITERIA OF PERINATAL DAMAGE OF CENTRAL NERVOUS SYSTEM AT PREMATURE NEWBORNS." Wiadomości Lekarskie 72, no. 8 (2019): 1512–16. http://dx.doi.org/10.36740/wlek201908118.

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Introduction: Fetal and neonatal hypoxia takes a special place among the damaging factors of central nervous system (CNS). All forms of oxygen deficiency are accompanied by the development of bioenergetic hypoxia, which leads to tension of metabolic processes of the organism. Metabolic effect of hypoxia includes stark reduce of mitochondrial activity due to a significant inhibition enzymes of the Krebs cycle: succinate dehydrogenase (SDH) and lactate dehydrogenase (LDH). In newborn babies is not always possible to objectively assess the condition of the CNS defeat, because very often the sever
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Cherniavska, Yu I., V. I. Pokhylko, O. Ye Akimov, S. M. Tsvirenko, and O. V. Yakovenko. "PROFILE OF NITRIC OXIDE METABOLISM INDICATORS IN PRETERM INFANTS WITH PERINATAL CENTRAL NERVOUS SYSTEM INJURIES." Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії 23, no. 4 (2023): 50–55. http://dx.doi.org/10.31718/2077-1096.23.4.50.

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Introduction. Premature infants often experience a heightened risk of brain damage, potentially leading to various disorders affecting motor, cognitive, behavioral, social, and sensory functions. The underlying pathological processes of hypoxic-ischemic central nervous system (CNS) injury predominantly stem from compromised cerebral blood flow and oxygen transport. Timely diagnosis and treatment options for prematurely born children with perinatal CNS damage remain limited. Nitric oxide, a universal regulator of physiological functions, plays a crucial role. Endothelial dysfunction, marked by
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Sorokovikova, T. V., A. M. Morozov, K. A. Aleksanyan, Yu I. Kovalchuk, and V. V. Frolova. "Epileptic seizures caused by hypoxic-ischemic damage to the central nervous system." Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery), no. 1 (January 19, 2024): 111–19. http://dx.doi.org/10.33920/med-01-2401-11.

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Epilepsy is a chronic disease of the brain. There are many risk factors and causes of this disease, but it is known that the peak incidence occurs in the first year of a child's life. This is due to the fact that this pathology in most cases is the outcome of perinatal damage to the central nervous system (CNS), which has a hypoxic-ischemic genesis. Hemodynamic disturbances that occur in hypoxia lead to various metabolic shifts, which is subsequently accompanied by neuronal damage and reduced inhibitory influence over all processes. Based on the analysis of literature data, we studied the mech
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Kravchenko, L. V., M. A. Levkovich, S. B. Berezhanskaya, et al. "Clinical and diagnostic significance of determining the cytokine status in infants with chronic cytomegalovirus infection against the background of hypoxic-ischemic CNS damage." CHILDREN INFECTIONS 21, no. 3 (2022): 28–32. http://dx.doi.org/10.22627/2072-8107-2022-21-3-28-32.

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Objective: based on the production of cytokines, to identify the immunological features of the chronic course of cytomegalovirus infection in children of the first year of life against the background of hypoxic-ischemic CNS damage.Research methods:108 newborns with cytomegalovirus infection occurring against the background of perinatal hypoxic-ischemic lesions of the central unequal system were examined. All observed patients immediately after the diagnosis of cytomegalovirus infection underwent an immunological examination, including the determination of the levels of interferon-alpha (IFN-α)
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Mankovskyi, Dmytro S. "Hypoxic-ischemic brain injuries in cardiosurgical patients (rationale of causal connections)." BULLETIN OF MEDICAL AND BIOLOGICAL RESEARCH 4, no. 1 (2022): 64–69. http://dx.doi.org/10.11603/bmbr.2706-6290.2022.1.12972.

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Summary. The presented article substantiates the materials on causation in the most common variants of hypoxic-ischemic brain lesions in cardiac surgery patients. The study showed that the functional changes assumed by the patient's brain (under the conditions of heart surgery using the resources of artificial circulation), reflects the state of the structural patterns of the whole organism. The aim of the study – to analyze the clinical and anamnestic materials on pathogenetic prototypes of hypoxic-ischemic lesions that occur in patients as a result of cardiac surgery. Materials and Methods.
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Dissertations / Theses on the topic "Hypoxic-ischemic CNS"

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Ezenagu, Uchenna Esther, and Jane Oluchi Nnajiofur. "Fnaerobic metabolism in premature newborn with hypoxic-ischemic lesion of CNS." Thesis, Sumy State University, 2015. http://essuir.sumdu.edu.ua/handle/123456789/41176.

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Aloziem, Nnenna Zinnah, and Obinna Nwokiea. "Aerobic metabolism in premature newborns with hypoxic-ischemic lesion of CNS." Thesis, Sumy State University, 2015. http://essuir.sumdu.edu.ua/handle/123456789/41233.

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Ekuase, Philip, and Mhando Catherine Samwel. "Neurospecific enolase - early diagnostical marker of CNS damage." Thesis, Sumy State University, 2015. http://essuir.sumdu.edu.ua/handle/123456789/41257.

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Касян, Світлана Миколаївна, Светлана Николаевна Касян, Svetlana Nikolaevna Kasyan, Г. В. Богданова, О. І. Гапієнко та Т. О. Желєзна. "Прогностична значимість вмісту мікроелементів у сечі новонароджених із гіпоксично-ішемічним ураженням ЦНС". Thesis, Сумський державний університет, 2016. http://essuir.sumdu.edu.ua/handle/123456789/48059.

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Гіпоксично-ішемічне ураження ЦНС (ГІУ ЦНС) є однією з найбільш актуальних медико-соціальних проблем сучасної неонатології та неврології. Наслідки гіпоксично-ішемічного ураження ЦНС визначаються формуванням неврологічних і соматичних розладів, які призводить до інвалідизації та соціальної дезадаптації. У кожної третьої дитини річного віку діагностується неврологічна патологія – від затримки психомоторного розвитку до тяжких форм дитячого церебрального параліча (ДЦП). Серед дітей, вперше визнаних інвалідами, 57% складають хворі на ДЦП. Метою нашого дослідження було підвищити ефективність діагно
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Маркевич, Віталій Едуардович, Виталий Эдуардович Маркевич, Vitalii Eduardovych Markevych та ін. "Особливості нервово-психічного розвитку дітей наприкінці першого року життя, які перенесли гіпоксично-ішемічне ураження ЦНС". Thesis, Сумський державний університет, 2016. http://essuir.sumdu.edu.ua/handle/123456789/48072.

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Перинатальні ураження ЦНС гіпоксично-ішемічного генезу є найбільш частою причиною неврологічних відхилень в періоді новонародженості і суттєво впливають на подальший фізичний та нервово-психічний розвиток (НПР) дитини. Мета дослідження: вивчити особливості НПР дітей наприкінці першого року життя, які перенесли гіпоксично-ішемічне ураження ЦНС (ГІУ ЦНС).
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Book chapters on the topic "Hypoxic-ischemic CNS"

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Yawno, Tamara, and Rod Hunt. "Recent Developments in Neonatal Seizure Interventions." In Current Treatments for Epilepsy [Working Title]. IntechOpen, 2025. https://doi.org/10.5772/intechopen.1008914.

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Neonatal seizures, a leading neurological disorder, occur in 1 to 3 per 1000 live births, with higher incidence in premature infants. Despite advancements in neonatal care reducing mortality, long-term morbidity—such as cerebral palsy, developmental delays, and post-neonatal epilepsy—remains a significant concern. Neonatal seizures are predominantly symptomatic of acute brain injury, with common causes including hypoxic-ischemic encephalopathy (HIE) in term infants and intraventricular hemorrhage in preterm infants, along with CNS infections, metabolic disorders, and brain malformations. Recen
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