Academic literature on the topic 'ICG'

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Journal articles on the topic "ICG"

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Zhang, Jinguo, Xinghua Han, Lin Lin, Jian Chen, Feng Wang, Qi Ding, Li Hao, et al. "Unraveling the Expression Patterns of Immune Checkpoints Identifies New Subtypes and Emerging Therapeutic Indicators in Lung Adenocarcinoma." Oxidative Medicine and Cellular Longevity 2022 (February 7, 2022): 1–19. http://dx.doi.org/10.1155/2022/3583985.

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Immune checkpoint genes (ICGs) play pivotal roles in tumor immune microenvironment (TIME), and thus, targeting them represents a promising strategy for cancer immunotherapy. However, the genetic landscape of ICGs in lung adenocarcinoma (LUAD) is still unknown. Herein, we comprehensively evaluated the ICG expression profiles of 1439 LUAD samples and linked ICG expression patterns with infiltration of immune cells, clinical features, and response to immune checkpoint blockade (ICB). The ICGscore was developed to quantify ICG expression patterns of individual patient by principal component analysis algorithms. Three distinct ICG expression patterns and three ICG-related genomic clusters were determined, which were implicated in different clinical outcomes, level of immune infiltrates, and biological process. LUAD patients were subdivided into high- and low-ICGscore subgroups. Patients with higher ICGscore were characterized by favorable survival outcomes, increased immune cell infiltration, and enhanced expression of ICGs. Further analysis revealed that lower ICGscore was associated with greater tumor mutation loads and higher mutation rates of TTN, KEAP1, and ZFHX4. High ICGscore has the potential to be a robust indicator in clinical benefit of immunotherapy. Taken together, unraveling the ICG expression patterns will advance our understanding of heterogeneity of TIME and guides more effective immunotherapeutic strategies in LUAD.
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Duan, Y., and Y. Li. "P646 Utilisation of indocyanine green fluorescence imaging for Crohn’s disease following intestinal resection." Journal of Crohn's and Colitis 14, Supplement_1 (January 2020): S534. http://dx.doi.org/10.1093/ecco-jcc/jjz203.774.

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Abstract Background Growing evidences have shown that there are important advantages related to the utilisation of indocyanine green fluorescence imaging (ICG-FI) to reduce the risk of postoperative anastomotic leakage (AL) in colorectal surgery. However, the impact of ICG-FI on postoperative AL of Crohn’s disease (CD) following intestinal resection has not been investigated. Methods This is a retrospective study of consecutive CD patients who were treated with intestinal resection and anastomosis at a single institution between January 2017 and August 2019. The cohort was divided into 2 groups, those with ICG-FI compared with those without ICG-FI for intestinal resection. ICG was administered intravenously with a bolus of 5 mg, and the intestinal perfusion was evaluated by a SPY Elite system. Their baseline characteristics and perioperative outcomes were further analysed. Results No adverse reactions were recorded. Of the 88 CD patients who underwent intestinal resection, 36 patients underwent ICG-FI during intestinal resection, while 52 CD patients who underwent routine intestinal resection were from a prospectively maintained database. The 2 groups were similar in terms of patient demographics, immunosuppressive medication use, and the procedural factors. In patients with ICG-FI, poor perfusion of the bowel judged by ICG-FI led to additional intestinal resection in 25% (9/36). ICG-FI reduces the AL rate from 13.5% (7 leaks) of non-ICF-FI group to 8.3% (3 leaks) in ICG-FI group (p = 0.456). Forty-four (50%) patients had previous intestinal resection. Overall, 10 anastomotic leaks were identified (11.4% leak rate). There were 2 leaks (4.5%) detected in patients with no previous intestinal resection, compared with 8 leaks (18.2%) identified in patients with a history of previous intestinal resection (p = 0.044). The number of previous resections correlated with increasing risk for AL (correlation coefficient = 0.998). In univariate analysis, steroid use, CRP level and preoperative weight loss >10% in 6 months were independently associated with AL. Conclusion ICG-FI is applicable to intestinal resection for CD and may play a role in perfusion-related AL. A large prospective randomised trial should be warranted.
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Hide, Takuichiro, Shigetoshi Yano, Naoki Shinojima, and Jun-ichi Kuratsu. "Usefulness of the indocyanine green fluorescence endoscope in endonasal transsphenoidal surgery." Journal of Neurosurgery 122, no. 5 (May 2015): 1185–92. http://dx.doi.org/10.3171/2014.9.jns14599.

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OBJECT To avoid disorientation during endoscopic endonasal transsphenoidal surgery (ETSS), the confirmation of anatomical landmarks is essential. Neuronavigation systems can be pointed at exact sites, but their spatial resolution power is too low for the detection of vessels that cannot be seen on MR images. On Doppler ultrasonography the shape of concealed arteries and veins cannot be visualized. To address these problems, the authors evaluated the clinical usefulness of the indocyanine green (ICG) endoscope. METHODS The authors included 38 patients with pituitary adenomas (n = 26), tuberculum sellae meningiomas (n = 4), craniopharyngiomas (n = 3), chordomas (n = 2), Rathke's cleft cyst (n = 1), dermoid cyst (n = 1), or fibrous dysplasia (n = 1). After opening the sphenoid sinus and placing the ICG endoscope, the authors injected 12.5 mg of ICG into a peripheral vein as a bolus and observed the internal carotid arteries (ICAs), cavernous sinus, intercavernous sinus, and pituitary. RESULTS The ICA was clearly identified by a strong fluorescence signal through the dura mater and the covering thin bone. The intercavernous and cavernous sinuses were visualized a few seconds later. In patients with tuberculum sellae meningiomas, the abnormal tumor arteries in the dura were seen and the vague outline of the attachment was identified. At the final inspection after tumor removal, perforators to the brain, optic nerves, chiasm, and pituitary stalk were visualized. ICG fluorescence signals from the hypophyseal arteries were strong enough to see and spread to the area of perfusion with the passage of time. CONCLUSIONS The ICA and the patent cavernous sinus were detected with the ICG endoscope in real time and at high resolution. The ICG endoscope is very useful during ETSS. The authors suggest that the real-time observation of the blood supply to the optic nerves and pituitary helps to predict the preservation of their function.
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Thakur, Binay, Aiming Li, Mukti Devkota, Manish Chaudhary, and Yogesh Regmi. "Fluoroscence Angiography for Assessment of Gastric Conduit: Initial Experience from a Tertiary Care Center." Nepalese Journal of Cancer 3, no. 1 (October 11, 2019): 13–18. http://dx.doi.org/10.3126/njc.v3i1.25909.

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Introduction: Anastomotic leak (AL) after surgery for esophageal cancer remains a main cause of postoperative morbidity and mortality. Poor tissue perfusion at the site of anastomosis is one of the major factors for leak. We aimed to review the results of Indocyanine Green dye (ICG) with a goal to decrease the leak rate. Methods: Patients with cancer of esophagus and gastroesophageal junction were subjected to either upfront surgery or preoperative chemoradiation/ chemotherapy followed by surgery. Stomach was used for reconstruction. Intravenous injection of 5 mg – 10 mg ICG was given and vascular perfusion was assessed with infrared light of laparoscopic telescope. Gastroesophageal anastomosis was made at the site of adequate ICG perfusion. These patients (ICG group) was compared to the other group of patients in whom ICG was not used (Non-ICG group). Results: 28 and 396 patients belonged to ICG and Non-ICG group, respectively. 61% in ICG group and 32% in Non-ICG group had preoperative treatment (p <.001). AL was observed in 7% and 16% in ICG and Non-ICG group, respectively (p = 0.2). Healing time of leak was 15 days in ICG group and 32 days in Non-ICG group (p = .03). One patient required revision of anastomotic site based on ICG finding. There was no adverse reaction related to ICG injection. Conclusion: Fluoroscence angiography using ICG is a safe method for evaluation of vascular perfusion of gastric conduit. Though the leak rate was not statistically different in the two groups, ICG group required lesser time for complete resolution of AL, which might indicate lesser severity of anastomotic disruption.
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Castagneto-Gissey, Lidia, Maria Francesca Russo, Alessandra Iodice, James Casella-Mariolo, Angelo Serao, Andrea Picchetto, Giancarlo D’Ambrosio, et al. "Intracholecystic versus Intravenous Indocyanine Green (ICG) Injection for Biliary Anatomy Evaluation by Fluorescent Cholangiography during Laparoscopic Cholecystectomy: A Case–Control Study." Journal of Clinical Medicine 11, no. 12 (June 17, 2022): 3508. http://dx.doi.org/10.3390/jcm11123508.

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(1) Background: Fluorescence cholangiography has been proposed as a method for improving the visualization and identification of extrahepatic biliary anatomy in order to possibly reduce injuries and related complications. The most common method of indocyanine green (ICG) administration is the intravenous route, whereas evidence on direct ICG injection into the gallbladder is still quite limited. We aimed to compare the two different methods of ICG administration in terms of the visualization of extrahepatic biliary anatomy during laparoscopic cholecystectomy (LC), analyzing differences in the time of visualization, as well as the efficacy, advantages, and disadvantages of both modalities. (2) Methods: A total of 35 consecutive adult patients affected by acute or chronic gallbladder disease were enrolled in this prospective case–control study. Seventeen patients underwent LC with direct gallbladder ICG injection (IC-ICG) and eighteen subjects received intravenous ICG administration (IV-ICG). (3) Results: The groups were comparable with regard to their demographic and perioperative characteristics. The IV-ICG group had a significantly shorter overall operative time compared to the IC-ICG group (p = 0.017). IV-ICG was better at delineating the duodenum and the common hepatic duct compared to the IC-ICG method (p = 0.009 and p = 0.041, respectively). The cystic duct could be delineated pre-dissection in 76.5% and 66.7% of cases in the IC-ICG and IV-ICG group, respectively, and this increased to 88.2% and 83.3% after dissection. The common bile duct could be highlighted in 76.5% and 77.8% of cases in the IC-ICG and IV-ICG group, respectively. Liver fluorescence was present in one case in the IC-ICG group and in all cases after IV-ICG administration (5.8% versus 100%; p < 0.0001). (4) Conclusions: The present study demonstrates how ICG-fluorescence cholangiography can be helpful in identifying the extrahepatic biliary anatomy during dissection of Calot’s triangle in both administration methods. In comparison with intravenous ICG injection, the intracholecystic ICG route could provide a better signal-to-background ratio by avoiding hepatic fluorescence, thus increasing the bile duct-to-liver contrast.
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Mielke, Dorothee, Vesna Malinova, and Veit Rohde. "Comparison of Intraoperative Microscopic and Endoscopic ICG Angiography in Aneurysm Surgery." Operative Neurosurgery 10, no. 3 (September 1, 2014): 418–25. http://dx.doi.org/10.1227/neu.0000000000000345.

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Abstract BACKGROUND: Indocyanine green (ICG) angiography is used to detect vessel compromise by the clip, residual aneurysms after clipping, or persistent aneurysm filling due to incomplete clipping. For ICG angiography, the microscope must be in a direct line-of-sight with the region of interest, limiting the identification of hidden arteries and dog-ear remnants. OBJECTIVE: To use a prototype endoscope for visualization of ICG fluorescence in hidden regions of the microsurgical field and evaluate its potential usefulness compared with microscopic ICG angiography (m-ICG-A) in a consecutive series of 30 aneurysms in 26 patients. METHODS: In selected cases, before and routinely after microsurgical clip application, m-ICG-A and endoscopic ICG angiography (e-ICG-A) were performed. The information gained by m-ICG-A was compared with that gained by e-ICG-A. RESULTS: E-ICG-A was technically feasible in all operations. Intra-arterial fluorescence could be visualized up to 10 times longer with the endoscope than with the microscope. The endoscope allowed a closer view on the fluorescent artery-aneurysm-complex. e-ICG-A provided more information than m-ICG-A in 11 operations (confirmation of unhindered blood flow in microscopically hidden vessels [n = 6], neck remnant identification [n = 2], neck remnant exclusion [n = 2], blood flow control in 2 distant clipped aneurysms [n = 1]). In 14 operations, identical information was obtained, and in 1 operation e-ICG-A was inferior because of trapped intra-aneurysmal fluorescence. CONCLUSION: In selected cases, e-ICG-A provides the neurosurgeon with information that cannot be obtained by m-ICG-A. e-ICG-A is capable of emerging as a useful adjunct in aneurysm surgery and has the potential to further improve operative results.
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Sato, Tomohito, Yoko Karasawa, Sho Ishikawa, Manzo Taguchi, Tadashi Muraoka, Masataka Ito, and Masaru Takeuchi. "Potential Phototoxicity of Indocyanine Green in Retinal Pigment Epithelial Cells after Angiography under Ambient Illumination." Oxidative Medicine and Cellular Longevity 2018 (June 27, 2018): 1–10. http://dx.doi.org/10.1155/2018/6065285.

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Indocyanine green (ICG) angiography is an indispensable inspection to diagnose and treat for chorioretinal diseases. In this study, we investigated the phototoxicity of ICG on RPE cells at the levels of residual ICG after angiography under ambient light. After incubation of ARPE-19 cells in a colorless medium containing 0 to 10 μg/mL ICG for 24 hours in the dark or under 2000 lx illumination from a fluorescent lamp, cell viability decreased and cell death rate increased in cultures with more than 5.0 μg/mL ICG under illumination. In culture with 10 μg/mL ICG under illumination, morphology of cells changed to be oval and TUNEL- and malondialdehyde-positive cells increased compared to other cultures with ICG in the dark or without ICG under illumination. Furthermore, the level of intracellular reactive oxygen species was also elevated. On the other hand, toxicity of ICG denatured by illumination was not observed. Blocking green to red light overlapping wavelengths of ICG absorbance exhibited decreased cell death rate. The present study indicated that ICG at the estimated intravenous concentrations after ICG angiography induces potential phototoxicity on human RPE cells via oxidative damage under continuous ambient illumination and that the cytotoxicity is reduced by blocking green to red light wavelengths.
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Furuse, Motomasa, Ryo Hiramatsu, and Toshihiko Kuroiwa. "Intraoperative ICG Angiography." Neurosurgery 70, no. 4 (April 2012): E1056. http://dx.doi.org/10.1227/neu.0b013e31824869d3.

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Howe, Lucy. "ICG and AMPPPE." Ophthalmology 103, no. 6 (June 1996): 863. http://dx.doi.org/10.1016/s0161-6420(96)30602-7.

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Benouar, Sara, Abdelakram Hafid, Mokhtar Attari, Malika Kedir-Talha, and Fernando Seoane. "Systematic variability in ICG recordings results in ICG complex subtypes – steps towards the enhancement of ICG characterization." Journal of Electrical Bioimpedance 9, no. 1 (December 19, 2018): 72–82. http://dx.doi.org/10.2478/joeb-2018-0012.

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Abstract The quality of an impedance cardiography (ICG) signal critically impacts the calculation of hemodynamic parameters. These calculations depend solely on the identification of ICG characteristic points on the ABEXYOZ complex. Unfortunately, contrary to the relatively constant morphology of the PQRST complex in electrocardiography, the waveform morphology of ICG data is far from stationary, which causes difficulties in the accuracy of the automated detection of characteristic ICG points. This study evaluated ICG recordings obtained from 10 volunteers. The results indicate that there are several different waveforms for the ABEXYOZ complex; there are up to five clearly distinct waveforms for the ABEXYOZ complex in addition to those that are typically reported. The differences between waveform types increased the difficulty of detecting ICG points. To accurately detect all ICG points, the ABEXYOZ complex should be analyzed according to the corresponding waveform type.
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Dissertations / Theses on the topic "ICG"

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Chan, Lai Sheung. "Therapeutic potential of a Wnt modulator ICG-001 on nasopharyngeal carcinoma." HKBU Institutional Repository, 2017. https://repository.hkbu.edu.hk/etd_oa/410.

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According to the cancer stem cells (CSCs) hypothesis, CSCs are responsible for the treatment failures. CSCs are a subset of cells possessing stemness properties within the heterogeneous tumor mass. Therapeutic intervention on Wnt signaling is of our great interest because an aberrant Wnt signaling is an important driver to maintain the potency of CSCs. In nasopharyngeal carcinoma (NPC), deregulated expression of the Wnt signaling components is frequently observed. ICG-001 is a selective Wnt modulator (CBP antagonist) that specifically interrupts the interaction between β-catenin and CBP, thereby encourages the interaction between β-catenin and p300 and the subsequent differentiation and reduction of the CSCs subset. For this reason, the present study aimed to evaluate the therapeutic potential of ICG-001 in NPC. Results showed that ICG-001 inhibited both the migration of the NPC cells and the formation of tumor spheres. In the first part of the mechanistic studies (Chapter 3), ICG-001 was found to restore the expression of miR-150 in NPC cells. MiR-150 was further found to directly reduce CD44 expression and inhibit NPC cell migration. In the second part of the mechanistic studies (Chapter 4), ICG-001 was found to reduce the expression of Evi1 in NPC cells. The effect was accompanied with the inhibition of both the NPC cells migration and the tumor spheres formation. Two molecular axes, namely miR-96/Evi1/miR-449a and survivin/Evi1/miR-449a, were found to be involved in the inhibition of the tumor cell migration and spheroids formation. The therapeutic potential of using this CBP antagonist (ICG-001) in NPC, namely the in vitro and in vivo efficacy of ICG-001 combined with cisplatin, was examined (Chapter 5). Concurrent treatment of ICG-001 and cisplatin exhibited a synergistic inhibition on the in vitro growth and the tumor sphere forming capacity of NPC cells as well as the growth of NPC xenografts. Taken together, results presented in this thesis suggested that ICG-001 (PRI-724 is the analog of ICG-001 currently used in clinical trials) has a therapeutic potential in NPC.
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Granda, Barrena Juan Renato. "Sistema de software para el manejo de información de entidades al ICG." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2015. http://hdl.handle.net/10757/578662.

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Mérian, Juliette. "Développement et caractérisation in vivo de nanoparticules lipidiques biocompatibles au moyen des techniques d’imagerie de fluorescence et nucléaire." Thesis, Paris 5, 2012. http://www.theses.fr/2012PA05P614/document.

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La nanomédecine est un secteur d’activité en plein essor depuis le développement des liposomes, nanovecteurs permettant d’encapsuler des molécules hydrosolubles ou amphiphiles pour la délivrance de médicament. Les nouveaux agents thérapeutiques synthétisés étant de plus en plus lipophiles, le développement de nouveaux vecteurs nanoparticulaires permettant leur transport constitue aujourd’hui un enjeu majeur. Les lipidots, nanoparticules lipidiques solides biocompatibles de 50 nm de diamètre, composées d’un mélange d’huile, de cire et de lécithine stabilisées par une couronne de surfactants pegylés, permettent de transporter des composés hautement hydrophobes en leur cœur. Des agents nucléaires pour la tomographie à émission monophotonique et des agents de fluorescence ont pu y être encapsulés pour l’évaluation de la biodistribution de ces nanoparticules chez la souris saine ainsi que dans différents modèles tumoraux. Un peptide de ciblage, le cRGD a également été greffé à la surface des lipidots afin d’adresser préférentiellement, dans les 3 premières heures après injection, les nanoparticules vers les tumeurs surexprimant les intégrines αvβ3. Une biodistribution particulière des lipidots dans les organes stéroïdiens (surrénales, ovaires) a été observée avec une localisation spécifique dans les zones synthétisant les hormones stéroïdiennes (le corps jaune pour les ovaires, la zone corticale pour les surrénales). Cette affinité unique a été mise à projet pour cibler des tumeurs hormono-dépendantes, ainsi que pour encapsuler des hormones ovariennes pour le traitement hormonal substitutif ou le contrôle de la procréation
Nanomedicine is a fast growing field since the development of liposomes, nanovectors able to encapsulate in their core or phospholipid bilayer hydrophilic or amphiphilic molecules for drug delivery purposes. Nowadays, most of the new synthetized therapeutic compounds are hydrophobic, necessitating the development of new types of nanocargos. Lipidots, 50 nm diameter biocompatible solid lipid nanoparticles, composed of a mixture of oil, wax and lecithin stabilized by a shell of pegylated surfactants, are used to encapsulate highly hydrophobic compounds in their core for vectorization purpose. Nuclear agents for simple photon emission tomography, or near infrared fluorescent dyes, have been encapsulated in the lipidot core, to assess the biodistribution of these nanoparticles in healthy mice as well as in a large range of tumor models. A targeting peptide, the cRGD motif, was also grafted on the surface of lipidots to vectorize preferentially the nanoparticles to tumors overexpressing αvβ3 integrins. An unexpected lipidot biodistribution in steroid organs (adrenal, ovary) was observed, with a specific localization in areas of steroid hormones synthesis (corpus luteum in ovaries, cortex for adrenals). This unique lipidot affinity was used to target hormono-dependent cancer cells, as well as to encapsulate ovarian hormones, like estradiol or ethynil estradiol, for hormone substitution therapy or birth control
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Warn, Tilman F. B. [Verfasser]. "Intraoperative Messung der Gewebsperfusion von Nierentransplantaten mittels ICG-Angiografie / Tilman F. B. Warn." Lübeck : Zentrale Hochschulbibliothek Lübeck, 2016. http://d-nb.info/1099333814/34.

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Chiang, Yiu Chun. "ICG-001 inhibits metastasis of nasopharyngeal carcinoma via miRNA-134/β1-integrin axis." HKBU Institutional Repository, 2020. https://repository.hkbu.edu.hk/etd_oa/879.

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Background: ICG-001, an antagonist of CBP (CREB-binding protein), has been demonstrated to exert anti-tumor activity via the modulation of the Wnt signalling pathway. It has previously been demonstrated that miRNAs play an important role in ICG-001-mediated tumor suppression. In the present study, the role of miRNA-134 and 1-integrin in ICG-001-mediated anti-tumor activity in nasopharyngeal carcinoma (NPC) was examined. Methods: NPC cell lines including C666-1, HONE-1 and HK-1 were used in this study. RT-PCR and Western blot were used to study the expression of miRNA-134 and the protein expression of the target proteins, respectively. Confocal microscopy was used to analyse the subcellular localization of 1-integrin. In the functional studies, in vitro endothelial adhesion assay and in vivo nude mice model were used to evaluate the adhesion and migration of ICG-001-treated NPC cells in animals, respectively. Results: ICG-001 was found to up-regulate the expression of miRNA-134 and down-regulate 1-integrin in NPC cells. The effect was accompanied with the inhibition of the adhesion of NPC cells to lung endothelial cells. In addition, over-expression of miRNA-134 would down-regulate the expression of 1-integrin. Results from 1-integrin 3'UTR Renilla luciferase reporter assay confirmed that 1-integrin is a target of miRNA-134 in NPC cells. In the animal study, the ability of ICG-001-pretreated NPC cells or stable miRNA-134 expressing NPC cells to migrate to the mouse lung was greatly reduced. Conclusion: The CBP antagonist ICG-001 may further be developed as an anti-tumor agent for the treatment of nasopharyngeal carcinoma
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Pons, i. Playà Gemma. "Planificación pre-operatoria de anastomosis linfático-venosas mediante ICG-linfografía y linfo-resonancia magnética." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/383993.

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El linfedema es una enfermedad crónica progresiva originada por una anomalía funcional del sistema linfático, que puede llegar a ser muy invalidante. El cáncer de mama es la primera causa de linfedema en países desarrollados. A pesar de su notable incidencia (más de 2.000 nuevos casos por año secundarios a cáncer de mama en España), no ha recibido la atención necesaria durante mucho tiempo. Y esto se debe principalmente a la dificultad para visualizar las finas estructuras del sistema linfático y a la complejidad para entender su fisiopatología. Durante las últimas décadas ha resurgido un interés por el sistema linfático y sus patologías asociadas, con el objetivo de conseguir un tratamiento definitivo para el linfedema. La evolución de las técnicas de diagnóstico por imagen y el desarrollo de las técnicas de supermicrocirugía han permitido avanzar en el campo de la linfología. Las anastomosis linfático-venosas son un tratamiento quirúrgico para el linfedema, que requiere la identificación y mapeo de los canales linfáticos funcionantes. Actualmente ICG-Linfografía se ha posicionado como la técnica de elección para evaluar la funcionalidad del sistema linfático, y para seleccionar los candidatos para cirugía reconstructiva del sistema linfático. La Linfo-Resonancia Magnética ofrece imágenes 3D tanto del sistema linfático superficial como profundo de una extremidad completa. Estas dos exploraciones permiten obtener imágenes del sistema linfático con suficiente resolución temporal y espacial para describir los vasos linfáticos funcionantes. Esto será esencial para la planificación pre-operatoria de la microcirugía de anastomosis linfático-venosas. Presentamos nuestro protocolo para abordar el tratamiento quirúrgico del linfedema. La aplicación de este protocolo representará un avance para unificar criterios en la selección de pacientes y para conseguir una cirugía más segura, eficaz y racional.
Lymphedema is a chronic progressive disease caused by abnormal lymphatic drainage. The main cause in developed countries is related to malignancy, especially breast cancer, and its treatment. Despite its significant incidence (more than 2.000 new cases per year due to breast cancer in Spain), this disorder did not receive the attention it deserved for a long time, mainly due to the complexity in understanding the physiology of the lymphatic system and the difficulty in visualizing its anatomy. In recent decades, however, interest in lymphedema has been revived with the intent to pursue a definitive surgical treatment. Recent advances in diagnostic imaging techniques and the development of supermicrosugery have led to significant progress in the field of lymphology. Lymphatico-venular anastomosis is a surgical treatment for lymphedema that requires the identification and mapping of functional lymphatic channels. Currently, ICG-lymphography is the primary imaging modality to evaluate lymphedema functionality and to select the candidates for reconstructive surgical techniques. 3T MR lymphangiography offers 3D visualization of both the superficial and deep lymphatic system of an entire limb. These non-invasive tests provides images of the lymphatic system with sufficient temporal and spatial resolution to depict functional lymphatic vessels. Such knowledge is essential for preoperative planning of LVA microsurgery. We present our protocol to approach surgical treatment for lymphedema. The application of this protocol represents a step forward in unifying the criteria to select patients and to achieve a safe, effective and rational surgery.
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Keršulytė, Gintarė. "Širdies signalų analizės metodų paieška ir kūrimas." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2007. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2007~D_20070816_142805-77618.

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Didelė dalis širdies susirgimų diagnostinių kriterijų gaunama registruojant ir analizuojant kardiosignalus, kurie atspindi tiek elektrinės širdies veiklos sutrikimus (EKG), tiek ir hemodinaminės bei mechaninės veiklos pokyčius, t.y. impedanskardiograma (IKG) ir seismokardiograma (SKG). Dar daugiau, efektyvus širdies susirgimų diagnostikos problemų sprendimas yra naujų kardiosignalų analizės technologijų kūrimas. Jau kelis dešimtmečius Furjė transformacija taikoma EKG dažnumų analizei, tuo tarpu kai IKG ir SKG dažnio charakteristikų vertinimui šis metodas nebuvo naudojamas. Darbo tikslas buvo pritaikyti Furjė analizę įvertinant bei palyginant tris sinchroniškai užregistruotus kardiosignalus, nes jie atspindi elektrinės širdies, hemodinaminės bei mechaninės širdies veiklos pokyčius geriau nei vienas EKG signalas. Kitas darbo tikslas buvo pritaikyti Furjė analizę įvertinant bei palyginant trijų sinchroniškai užregistruotų signalų - EKG, IKG ir SKG dažnio charakteristikas ir koherenciją bei klasifikuoti dvi grupes - "sveikas" ir "ligonis". Rezultatai rodo, kad koherencijos vertinimas ir spektrinė analizė gali būti naudinga gali būti naudingas širdies kraujagyslių bei plaučių sistemų ligų diagnostikai.
A big part of heart disease diagnostics criteria is collected by registration and analysis of cardio signals that reflect the disturbances of the electric heart activity – electrocardiogram (EСG), changes of hemodynamic - impedance cardiograms (IСG) and mechanic activity - seismocardiogram (SСG). ECG analysis is generally applying in clinic practice, but usually in visual way only. Due to the development of the technologies, the bigger amount of data could be stored and more exact analysis of information could be carried out. Therefore, a solution of problem of effective diagnostics of heart diseases is the creation of new technologies for analysis of cardio signals. Previously Fourier series were applied to frequency analysis of ECG, but this method was not applied for estimation of ICG and SCG frequency characteristics. In this thesis the frequency analysis method was applied to three cardio signals, because they reflect the electrical and mechanical work of the human heart better as entirely ECG signal. The main aim of this work was to adapt Fourier transformation to assessing and comparing some characteristics of hereinbefore signals, such as coherence and classify two searching groups - “healthy” and “sick”. Results showed that rating of coherence and spectral analysis could be useful for rightly analyzing and classifying the searching groups.
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Mork, Christian. "ICG-Clearance und hepatovenöse Sauerstoffsättigung als erweitertes Monitoring der postoperativen Leberfunktion eine prospektive, klinische Beobachtungsstudie /." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=972767266.

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Kland, Konstanze. "Evaluation der ICG-Clearance (LIMON®) zur Diagnostik von Leberfunktionsstörungen bei Patienten nach allogener Stammzelltransplantation." Diss., lmu, 2011. http://nbn-resolving.de/urn:nbn:de:bvb:19-130870.

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Alexandersson, Pelle. "Psykometrisk prövning av PG-13; ett självskattningsinstrument för ihållande sorg." Thesis, Stockholms universitet, Psykologiska institutionen, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-43566.

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Frågan om ”normal” respektive ”patologisk” sorg har under en lång tid varit ett omdiskuterat ämne inom psykologin och psykiatrin. En grupp forskare har tagit fram kriterier på ett syndrom som fått benämningen ihållande sorg (”prolonged grief”). Studier har visat på att ihållande sorg är ett distinkt syndrom separat från depression, posttraumatisk stressyndrom och generaliserat ångestsyndrom. Ihållande sorg föreslås ingå som en diagnos i de kommande versionerna av de diagnostiska manualerna DSM och ICD. Syftet med denna studie var att översätta självskattningsinstrumentet Prolonged Grief Disorder (PG-13) till svenska, och undersöka dess reliabilitet och validitet genom bland annat en explorativ och konfirmatorisk faktoranalys. Studien genomfördes på ett annonsrekryterat heterogent sample (n=162 varav 90 % var kvinnor) vad gäller typ av dödsfall och relation till den avlidne. Respondenterna besvarade en webb- eller pappersenkät som bestod av 75 items. PG-13 bedöms ha en hög reliabilitet, god begrepps- och samtidig validitet samt en måttlig diskriminativ validitet.
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Books on the topic "ICG"

1

Guidance, Institute of Career. ICG international factsheets on guidance: Australia. Stourbidge: ICG, 2000.

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Bauer, Reimar. IDL-Referenz der ICG-Daten-Struktur. Jülich: Forschungszentrum, Zentralbibliothek, 2006.

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Kusano, Mitsuo, Norihiro Kokudo, Masakazu Toi, and Masaki Kaibori, eds. ICG Fluorescence Imaging and Navigation Surgery. Tokyo: Springer Japan, 2016. http://dx.doi.org/10.1007/978-4-431-55528-5.

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Guidance, Institute of Career. ICG international factsheets on guidance: New Zealand. Stourbidge: ICG, 2000.

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Guidance, Institute of Career. ICG international factsheets on guidance: United States of America. Stourbidge: ICG, 2000.

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International Congress on Glass. (19th 2001 Edinburgh, Scotland). XIX International Congress on Glass: ICG XIX, July 1-6, 2001, Edinburgh International Conference Centre, Scotland. Sheffield: Society of Glass Technology, 2001.

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Reference from the Lieutenant Governor in council: ICG Utilities (Ontario) Ltd. ; cogeneration project Boise Cascade Canada Ltd. Fort Frances. Toronto, Ont: Ontario Energy Board, 1989.

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International Conference on Geosynthetics (7th 2002 Nice, France). Geosynthetics: State of the art, recent developments : proceedings of the seventh International Conference on Geosynthetics, 7 ICG-Nice 2002, France, 22-27 September 2002. Edited by Delmas Philippe, Gourc J. P, Girard H, International Geosynthetics Society, and Comité français des géosynthétiques. Lisse: Balkema, 2002.

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Gernhardt, Robert. Ich, Ich, Ich: Roman. München: Heyne, 1995.

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Bego, Mark. Ice Ice Ice: The extraordinary Vanilla Ice story. New York: Bantam, 1991.

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Book chapters on the topic "ICG"

1

Spinoglio, Giuseppe. "ICG Fluorescence." In Robotics in General Surgery, 461–76. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-8739-5_36.

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Arora, Atul, Aniruddha Agarwal, and Vishali Gupta. "Normal ICG." In The Uveitis Atlas, 1–4. New Delhi: Springer India, 2019. http://dx.doi.org/10.1007/978-81-322-2506-5_10-2.

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Levesque, E., and F. Saliba. "ICG Clearance Monitoring in ICH Patients." In Yearbook of Intensive Care and Emergency Medicine, 646–57. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-92276-6_60.

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Levesque, E., and F. Saliba. "ICG Clearance Monitoring in ICU Patients." In Intensive Care Medicine, 646–57. New York, NY: Springer New York, 2009. http://dx.doi.org/10.1007/978-0-387-92278-2_60.

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Yamamoto, Takumi. "Indocyanine Green (ICG) Lymphography." In Congenital Vascular Malformations, 173–78. Berlin, Heidelberg: Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-46709-1_26.

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Kumon, Yoshiaki, Hideaki Watanabe, Shiro Ohue, and Takanori Ohnishi. "ICG Videoangiography in Neurosurgical Procedures." In ICG Fluorescence Imaging and Navigation Surgery, 31–45. Tokyo: Springer Japan, 2016. http://dx.doi.org/10.1007/978-4-431-55528-5_4.

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Han, Ho-Seong, and Jai Young Cho. "Application of Indocyanine Green (ICG)." In Color Atlas of Laparoscopic Liver Resection, 13. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-1546-7_5.

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Miwa, Mitsuharu. "Photodynamic Characteristics of ICG Fluorescence Imaging." In ICG Fluorescence Imaging and Navigation Surgery, 3–7. Tokyo: Springer Japan, 2016. http://dx.doi.org/10.1007/978-4-431-55528-5_1.

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Tagaya, Nobumi. "ICG Fluorescence Cholangiography During Laparoscopic Cholecystectomy." In ICG Fluorescence Imaging and Navigation Surgery, 389–96. Tokyo: Springer Japan, 2016. http://dx.doi.org/10.1007/978-4-431-55528-5_36.

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Kitai, Toshiyuki. "Principle and Development of ICG Method." In ICG Fluorescence Imaging and Navigation Surgery, 101–11. Tokyo: Springer Japan, 2016. http://dx.doi.org/10.1007/978-4-431-55528-5_8.

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Conference papers on the topic "ICG"

1

Rosen, Richard B., Mark Hathaway, John Rogers, Justin Pedro, Patricia Garcia, George M. Dobre, Rishard Weitz, and Adrian Gh Podoleanu. "Simultaneous OCT/SLO/ICG system." In Biomedical Optics 2006, edited by Valery V. Tuchin, Joseph A. Izatt, and James G. Fujimoto. SPIE, 2006. http://dx.doi.org/10.1117/12.648176.

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Crovisier, Jason, Baharak Bahmani, Reema Saleh, Valentine Vullev, and Bahman Anvari. "Effects of ICG concentration and particle diameter on photophysical properties of ICG-doped nanoparticles." In SPIE BiOS, edited by Samuel Achilefu and Ramesh Raghavachari. SPIE, 2014. http://dx.doi.org/10.1117/12.2042298.

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Tuchin, Valery V., Gregory B. Altshuler, Elina A. Genina, Alexey N. Bashkatov, Georgy V. Simonenko, Olga D. Odoevskaya, and Ilya V. Yaroslavsky. "ICG laser therapy of acne vulgaris." In Biomedical Optics 2004, edited by Steven L. Jacques and William P. Roach. SPIE, 2004. http://dx.doi.org/10.1117/12.531010.

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Zhu, L., Q. He, C. H. von Kerczek, L. D. T. Topoleski, and R. W. Flower. "Extraction of Flow Information in Choriocapillaris in Human Eyes From ICG Dye Angiography Images." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-33067.

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Indocyanine green (ICG) dye angiography has been used by ophthalmologists as a useful tool for routine examination of the vasculature of the choroid in human eyes. ICG dye angiography is performed by venous injecting of ICG dye, which is delivered to different vascular structures in the eyes at different times. A multi-spectral fundus camera is used to take the dye intensity images of the eye at a speed of thirty images per second. In this study, a new approach is developed to extract information of velocity distribution in the choriocapillaris and its feeding blood vessels from the ICG dye angiograms. The ICG dye intensity rise and decay curves are constructed from the ICG dye images at each image pixel location in the choriocapillaris. It is shown that the magnitude of the local velocity in the choriocapillaris is proportional to the transient of the ICG dye intensity curve. The approach allows the determination of the absolute value of the velocity in the choriocapillaris and is calibrated by the image data at two axial locations of a straight blood vessel of uniform cross-section area. The velocity image of the entire choriocapillaris is then constructed. This approach could be used in clinical applications for diagnostic purposes since it provides detailed quantified flow information in human eyes.
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Shan Liu, Keming Yue, Hua Yang, and Ting Guo. "The research on ICG signal de-noising." In 2016 IEEE Advanced Information Management, Communicates, Electronic and Automation Control Conference (IMCEC). IEEE, 2016. http://dx.doi.org/10.1109/imcec.2016.7867513.

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Grosenick, Dirk, Axel Hagen, Herbert Rinneberg, Rainer Macdonald, Alexander Pöllinger, Susen Burock, and Peter M. Schlag. "Fluorescence Imaging of Breast Cancer with ICG." In Biomedical Optics. Washington, D.C.: OSA, 2010. http://dx.doi.org/10.1364/biomed.2010.bsub3.

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Miwa, Mitsuharu, and Takahiro Shikayama. "ICG fluorescence imaging and its medical applications." In International Conference of Optical Instrument and Technology, edited by Shenghua Ye, Guangjun Zhang, and Jun Ni. SPIE, 2008. http://dx.doi.org/10.1117/12.817856.

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Larkin, Sean, Alessandro Invernizzi, David Beecher, Giovanni Staurenghi, and Tim Holmes. "Perfusion measures from dynamic ICG scanning laser ophthalmoscopy." In BiOS, edited by Fabrice Manns, Per G. Söderberg, and Arthur Ho. SPIE, 2010. http://dx.doi.org/10.1117/12.839534.

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Busch, Jr., David R., Zhongyao Zhao, Shoko Nioka, Arjun G. Yodh, Mitchell Schnall, Britton Chance, and Xavier Intes. "Fast CW imager for ICG and Gd kinetics." In Biomedical Optics 2006, edited by Fred S. Azar and Dimitris N. Metaxas. SPIE, 2006. http://dx.doi.org/10.1117/12.649400.

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"A NEW METHOD FOR ICG CHARACTERISTIC POINT DETECTION." In International Conference on Bio-inspired Systems and Signal Processing. SciTePress - Science and and Technology Publications, 2008. http://dx.doi.org/10.5220/0001057802440249.

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Reports on the topic "ICG"

1

Deng, Chun, Zhenyu Zhang, Zhi Guo, Hengduo Qi, Yang Liu, Haimin Xiao, and Xiaojun Li. Assessment of intraoperative use of indocyanine green fluorescence imaging on the number of lymph node dissection during minimally invasive gastrectomy: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2021. http://dx.doi.org/10.37766/inplasy2021.11.0062.

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Review question / Objective: Whether is indocyanine green fluorescence imaging-guided lymphadenectomy feasible to improve the number of lymph node dissections during radical gastrectomy in patients with gastric cancer undergoing curative resection? Condition being studied: Gastric cancer was the sixth most common malignant tumor and the fourth leading cause of cancer-related death in the world. Radical lymphadenectomy was a standard procedure in radical gastrectomy for gastric cancer. The retrieval of more lymph nodes was beneficial for improving the accuracy of tumor staging and the long-term survival of patients with gastric cancer. Indocyanine green(ICG) near-infrared fluorescent imaging has been found to provide surgeons with effective visualization of the lymphatic anatomy. As a new surgical navigation technique, ICG near-infrared fluorescent imaging was a hot spot and had already demonstrated promising results in the localization of lymph nodes during surgery in patients with breast cancer, non–small cell lung cancer, and gastric cancer. In addition, ICG had increasingly been reported in the localization of tumor, lymph node dissection, and the evaluation of anastomotic blood supply during radical gastrectomy for gastric cancer. However, it remained unclear whether ICG fluorescence imaging would assist surgeons in performing safe and sufficient lymphadenectomy.
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Pons, Aina, Annalisa Hauck, and Tarek Abdel Aziz. On Indocyanine Green Fluorescence and Autofluorescence in thyroid and parathyroid surgery: A systematic review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, February 2022. http://dx.doi.org/10.37766/inplasy2022.2.0067.

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Review question / Objective: Autofluorescence (AF) and Indocyanine Green Fluorescence (ICG) were used for the first time for parathyroid gland (PG) identification in 2011 and 2015, respectively, during thyroidectomy/parathyroidectomy. Authors reported promising results. We aim to understand the efficacy, technical challenges, cost-effectiveness, and impact on postoperative biochemical and clinical outcomes of such new techniques. Eligibility criteria: The language filter was set to allow for publications in English, German, Spanish, and French assessing the use of ICG and/or AF for PG identification. Only titles and abstracts, followed by the full text dating from 2008 to 2020 have been considered in this review. Existing systematic reviews were excluded from the results.
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Lu, Dengwei, Enjie Tang, Supeng Yin, Yizeng Sun, Yuquan Yuan, Tingjie Yin, Zeyu Yang, and Fan Zhang. Intraoperative strategies in identification and functional protection of parathyroid gland for patients with thyroidectomy: A network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2022. http://dx.doi.org/10.37766/inplasy2022.11.0109.

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Review question / Objective: To assess the roles of intraoperative visualization of parathyroid glands (IVPG) strategies including autofluorescence (AF), indocyanine green (ICG) fluorescence and carbon nanoparticles (CN) in identification and functional protection of parathyroid glands (PGs). Condition being studied: The IVPG strategy is essential for intraoperative identification and functional protection of PGs in patients undergoing thyroid surgery. Recent studies have revealed that autofluorescence (AF), indocyanine green (ICG) fluorescence, and carbon nanoparticles (CN) contribute to reducing the incidence of postoperative hypocalcemia by improving PGs identification(6-8). However, different IVPGs have respective superiority and inferiority in clinical application. Thus, this network meta-analysis aimed to systematically analyze the significance of IVPG strategy in identifying PGs and protecting their function.
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Lear, E., and R. Housley, eds. Response to the IANA Stewardship Transition Coordination Group (ICG) Request for Proposals on the IANA Protocol Parameters Registries. RFC Editor, August 2016. http://dx.doi.org/10.17487/rfc7979.

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Cenedese, Claudia, and Mary-Louise Timmermans. 2017 program of studies: ice-ocean interactions. Woods Hole Oceanographic Institution, November 2018. http://dx.doi.org/10.1575/1912/27807.

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The 2017 Geophysical Fluid Dynamics Summer Study Program theme was Ice-Ocean Interactions. Three principal lecturers, Andrew Fowler (Oxford), Adrian Jenkins (British Antarctic Survey) and Fiamma Straneo (WHOI/Scripps Institution of Oceanography) were our expert guides for the first two weeks. Their captivating lectures covered topics ranging from the theoretical underpinnings of ice-sheet dynamics, to models and observations of ice-ocean interactions and high-latitude ocean circulation, to the role of the cryosphere in climate change. These icy topics did not end after the first two weeks. Several of the Fellows' projects related to ice-ocean dynamics and thermodynamics, and many visitors gave talks on these themes.
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Blackman, Allen, Sahan Dissanayake, Adan Martinez Cruz, Leonardo Corral, and Maja Schling. Benefits of Titling Indigenous Communities in the Peruvian Amazon: A Stated Preference Approach. Inter-American Development Bank, December 2022. http://dx.doi.org/10.18235/0004678.

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We conduct a discrete choice experiment with leaders of a random sample of 164 Peruvian indigenous communities (ICs) - to our knowledge, the first use of rigorous stated preference methods to analyze land titling. We find that: (i) on average, IC leaders are willing to pay US$35,000-45,000 for a title, roughly twice the per community administrative cost of titling; (ii) WTP is positively correlated with the value of IC land and the risk of land grabbing; and (iii) leaders prefer titling processes that involve indigenous representatives and titles that encompass land with cultural value.
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Dallimore, S. R. Ice Bonding and Excess Ice. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1991. http://dx.doi.org/10.4095/132231.

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Coon, Max D. Sea Ice Model for Marginal Ice Zone. Fort Belvoir, VA: Defense Technical Information Center, September 2003. http://dx.doi.org/10.21236/ada615524.

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Coon, Max D. Sea Ice Model for Marginal Ice Zone. Fort Belvoir, VA: Defense Technical Information Center, September 2001. http://dx.doi.org/10.21236/ada626073.

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Karig, Fred. Ice Camp. Fort Belvoir, VA: Defense Technical Information Center, September 1999. http://dx.doi.org/10.21236/ada629717.

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