Journal articles: 'Identafi 3000'

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Lane, Pierre, Michele Follen, and Calum MacAulay. "Has Fluorescence Spectroscopy Come of Age? A Case Series of Oral Precancers and Cancers Using White Light, Fluorescent Light at 405 nm, and Reflected Light at 545 nm Using the Trimira Identafi 3000." Gender Medicine 9, no. 1 (February 2012): S25—S35. http://dx.doi.org/10.1016/j.genm.2011.09.031.

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Riedel, Wm R. "Identify: a Prolog program to help identify fossils." Computers & Geosciences 15, no. 5 (January 1989): 809–23. http://dx.doi.org/10.1016/0098-3004(89)90083-6.

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Xu, Wen. "Expression Data Analysis to Identify Biomarkers Associated with Asthma in Children." International Journal of Genomics 2014 (2014): 1–5. http://dx.doi.org/10.1155/2014/165175.

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Asthma is characterized by recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing. It is usually caused by a combination of complex and incompletely understood environmental and genetic interactions. We obtained gene expression data with high-throughput screening and identified biomarkers of children's asthma using bioinformatics tools. Next, we explained the pathogenesis of children's asthma from the perspective of gene regulatory networks: DAVID was applied to perform Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enriching analysis for the top 3000 pairs of relationships in differentially regulatory network. Finally, we found that HAND1, PTK1, NFKB1, ZIC3, STAT6, E2F1, PELP1, USF2, and CBFB may play important roles in children's asthma initiation. On account of regulatory impact factor (RIF) score, HAND1, PTK7, and ZIC3 were the potential asthma-related factors. Our study provided some foundations of a strategy for biomarker discovery despite a poor understanding of the mechanisms underlying children's asthma.

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Daou, Hikmat, and Wassim Raphael. "Identifying the Weight of Factors Affecting Creep of Concrete Using Factorial ANOVA." Key Engineering Materials 872 (January 2021): 21–25. http://dx.doi.org/10.4028/www.scientific.net/kem.872.21.

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Creep may affect structural behavior by violating service limit states, redistributing stress or losing prestress forces. For that, knowing the significance of factors that influence creep is a must to accurately predict it. This paper uses the Northwestern university (NU) database to investigate the factors that most affect long-term creep of concrete. Factorial ANOVA was applied to identify the significance of factors affecting creep of concrete at 3000 days using R software. The factorial ANOVA results showed that the sustained load and the relative humidity have the major effect on the value of concrete creep at 3000 days.

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Daou, Hikmat, and Wassim Raphael. "Identifying the Weight of Factors Affecting Creep of Concrete Using Factorial ANOVA." Key Engineering Materials 872 (January 2021): 21–25. http://dx.doi.org/10.4028/www.scientific.net/kem.872.21.

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Creep may affect structural behavior by violating service limit states, redistributing stress or losing prestress forces. For that, knowing the significance of factors that influence creep is a must to accurately predict it. This paper uses the Northwestern university (NU) database to investigate the factors that most affect long-term creep of concrete. Factorial ANOVA was applied to identify the significance of factors affecting creep of concrete at 3000 days using R software. The factorial ANOVA results showed that the sustained load and the relative humidity have the major effect on the value of concrete creep at 3000 days.

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Steilmann, Paula, Norimar D’Avila Denardin, Marisseia Raab, Ana Carolina Menezes, and Suzete Aparecida Lanza Destefano. "DETECÇÃO, QUANTIFICAÇÃO E IDENTIFICAÇÃO DE FITOBACTÉRIAS EM SEMENTES DE TRIGO." Nativa 7, no. 4 (July 1, 2019): 349. http://dx.doi.org/10.31413/nativa.v7i4.6710.

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A qualidade sanitária das sementes merece atenção, considerando os reflexos negativos que a associação de patógenos em sementes pode gerar. Este estudo objetivou detectar, quantificar e identificar bactérias fitopatogênicas em sementes de trigo. A incidência foi avaliada utilizando as sementes diretamente dispostas sobre os meios de cultura 523, WBC e XTS. Dez diferentes métodos de quantificação foram testados, utilizando 100, 500, 1000 e 3000 sementes com e sem incubação; 3000 sementes com centrifugação e 3000 trituradas. Através do meio 523 não foi possível avaliar a incidência devido a presença de contaminantes. Utilizando o meio WBC obtiveram-se incidências de 92, 82 e 78 % para os cultivares Quartzo, Marfin e BRS 331 respectivamente e com o meio XTS 68% de incidência na cultivar BRS 331. Os resultados permitiram observar que o melhor método para quantificação de bactérias em sementes de trigo foi a utilização de 3000 sementes com incubação, com trituração e com centrifugação. Os resultados das avaliações como morfologia colonial, testes bioquímicos e fisiológicos permitem concluir que as bactérias isoladas pertencem às espécies Xanthomonas translucens e Pseudomonas fuscovagine, sendo que, alguns desses isolados a identificação só foi possível ao nível de gênero sendo identificados como Xanthomonas e Pseudomonas.Palavras-chave: bacteriose; patogenicidade; patologia de sementes; triticum aestivum. DETECTION AND QUANTIFICATION OF PHYTOPATHOGENIC BACTERIA IN WHEAT SEED ABSTRACT: The sanitary quality of seeds deserves attention, considering the negative impact that the association of pathogens in seeds can generate. This study aimed detects, quantify and identify phytopathogenic bacteria gifts in wheat seeds. The incidence of bacteria was evaluated using the seeds directly arranged on the culture medium 523, WBC and XTS. Ten different methods of quantification of pathogenic bacteria were tested with 100, 500, 1000 and 3000 seeds with and without incubation; 3000 seeds with crushed and 3000 with centrifugation. Across the middle 523 was not possible to assess the impact due to the presence of contaminants. Using the WBC light yielded incidences of 92, 82 and 78 % for Quartzo, Marfim and BRS 331cultivars respectively. With the environment XTS 68 % incidence BRS 331. Results showed that the best method for quantification of bacteria in wheat seeds was to use incubation with 3000 seeds with milling and centrifuging. The isolates were identified by colony morphology, biochemical and physiological tests showed that the isolated bacteria belonging to the species Pseudomonas fuscovaginae and Xanthomonas translucens and genera Pseudomonas and Xanthomonas.Keywords: bacterial; pathogenicity; seed pathology; triticum aestivum.

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Shu, Xiang, Mark P. Purdue, Yuanqing Ye, Christopher G. Wood, Meng Chen, Zhaoming Wang, Demetrius Albanes, et al. "Multilevel-analysis identify a cis-expression quantitative trait locus associated with risk of renal cell carcinoma." Oncotarget 6, no. 6 (February 25, 2015): 4097–109. http://dx.doi.org/10.18632/oncotarget.3001.

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Murugesu, Jason Arunn. "Police could identify illegal drugs with magnetic levitation." New Scientist 245, no. 3263 (January 2020): 6. http://dx.doi.org/10.1016/s0262-4079(20)30005-1.

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Malik, Javed N., Ashutosh Kumar, Sravanthi Satuluri, Bishuddhakshya Puhan, and Asmita Mohanty. "Ground-Penetrating Radar Investigations along Hajipur Fault: Himalayan Frontal Thrust—Attempt to Identify Near Subsurface Displacement, NW Himalaya, India." International Journal of Geophysics 2012 (2012): 1–7. http://dx.doi.org/10.1155/2012/608269.

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The study area falls in the mesoseismal zone of 1905 Kangra earthquake (Mw 7.8). To identify appropriate trenching site for paleoseismic investigation and to understand the faulting geometry, ground-penetrating radar (GPR) survey was conducted across a Hajipur Fault (HF2) scarp, a branching out fault of Himalayan Frontal Thrust (HFT) in a foot hill zone of NW Himalaya. Several 2D and 3D profiles were collected using 200 MHz antenna with SIR 3000 unit. A 2D GPR profile collected across the HF2 scarp revealed prominent hyperbolas and discontinuous-warped reflections, suggesting a metal pipe and a zone of deformation along a low-angle thrust fault, respectively. The 3D profile revealed remarkable variation in dip of the fault plane and pattern of deformation along the strike of the fault.

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O’Brien, Myles, Matthew Kivell, William Wojcik, Ghislain d’Entremont, Derek Kimmerly, and Jonathon Fowles. "Step Rate Thresholds Associated with Moderate and Vigorous Physical Activity in Adults." International Journal of Environmental Research and Public Health 15, no. 11 (November 3, 2018): 2454. http://dx.doi.org/10.3390/ijerph15112454.

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Adults are recommended to engage in 150 min of moderate (MPA) to vigorous (VPA) aerobic physical activity per week, with the public health message of obtaining 3000 steps in 30 min. There is a paucity of research on step rate thresholds that correspond to absolute MVPA (moderate = 3 METs, vigorous = 6 METs) with no research evaluating adult relative MVPA (moderate = 40% VO2max, vigorous = 60% VO2max). Anthropometric differences also influence intensity-related step rate thresholds. The purpose of this study was to identify step rates across a range of walking intensities so that mathematical models incorporating anthropometric factors could be used to identify individualized MVPA step rate thresholds. Forty-three adults (25♀; age = 39.4 ± 15.2 years) completed a staged treadmill walking protocol with pedometers and indirect calorimetry: six-minutes at 2.4, 3.2, 4.0, 5.6, 6.4, 7.2 km/h. Mathematical modelling revealed absolute and relative MPA step rate thresholds of ~100 steps/minute (spm) and ~125 spm, respectively. VPA corresponded to step rates of ~133 spm and ~139 spm for absolute and relative thresholds respectively. The current public message of 3000 steps in 30 min is valid for absolute MPA. However, VPA is achieved at higher thresholds than previously reported, more than 130 spm for healthy adults.

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Kimberley, Michael M. "The use of sino-Japanese characters to identify locations on figures." Computers & Geosciences 26, no. 5 (June 2000): 603–5. http://dx.doi.org/10.1016/s0098-3004(99)00146-6.

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Kumar, Meera, and Robert G. Lowery. "Development of a High-Throughput Assay to Identify Inhibitors of ENPP1." SLAS DISCOVERY: Advancing the Science of Drug Discovery 26, no. 5 (January 5, 2021): 740–46. http://dx.doi.org/10.1177/2472555220982321.

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The innate immune response to cancer is initiated by cytosolic DNA, where it binds to cGAS and triggers type I interferon (IFN) expression via the STING receptor, leading to activation of tumor-specific T cells. Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) has been identified as the primary enzyme responsible for degrading cGAMP, and therefore it is under intense investigation as a therapeutic target for cancer immunotherapy. ENPP1 hydrolyzes cGAMP to produce AMP and GMP, and hydrolyzes ATP and other nucleotides to monophosphates and pyrophosphate. We developed a robust, high-throughput screening (HTS)-compatible enzymatic assay method for ENPP1 using the Transcreener AMP2/GMP2 Assay, a competitive fluorescence polarization (FP) immunoassay that enables direct detection of AMP and GMP in a homogenous format. The monoclonal antibody used in the Transcreener AMP2/GMP2 Assay showed more than 104-fold selectivity for AMP and GMP versus cGAMP, and 3000-fold selectivity for AMP over ATP, indicating that the assay can be used for detection at initial velocity with either substrate. A working concentration of 100 pM ENPP1 was determined as optimal with a 60 min reaction period, enabling screening with very low quantities of enzyme. A Z′ value of 0.72 was determined using ATP as substrate, indicating a high-quality assay. Consistent with previous studies, we found that ENPP1 preferred ATP as a substrate when compared with other nucleotides like GTP, ADP, and GDP. ENPP1 showed a 20-fold selectivity for 2′3′cGAMP compared with 2′3′c-diGMP and showed no activity with 3′3′c-diAMP. The Transcreener AMP2/GMP2 Assay should prove to be a valuable tool for the discovery of ENPP1 lead molecules.

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Lee, Young Hak, and Taekeun Oh. "The Measurement of P-, S-, and R-Wave Velocities to Evaluate the Condition of Reinforced and Prestressed Concrete Slabs." Advances in Materials Science and Engineering 2016 (2016): 1–14. http://dx.doi.org/10.1155/2016/1548215.

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The traditional P-wave ultrasonic measurement has been used for the condition assessment of general reinforced concrete structures for a long time, but the effects of prestressing applied to concrete structures such as long-span buildings and bridges on ultrasonic pulse velocity have not been studied clearly. Therefore, this study analyzed the statistical distribution of P-wave ultrasonic pulse velocities in reinforced and prestressed concrete slabs of 3000 × 3000 mm with a thickness of 250 mm. In addition, we measured S- and R-waves to identify experimental consistency by statistical analysis using the Kolmogorov-Smirnov goodness-of-fit test. The experimental results show that the P-, S-, and R-wave velocities increased slightly (2-3%) when prestressing was applied. As expected, the S- and R-wave measurements show better statistical reliability and potential for in situ evaluation than the P-wave because they are less sensitive to confinement and boundary conditions. The experimental results in this study can be used when assessing the condition of prestressed concrete structures through the velocities of elastic waves.

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Donneyong, Macarius M., Teng-Jen Chang, John W. Jackson, Michael A. Langston, Paul D. Juarez, Shawnita Sealy-Jefferson, Bo Lu, et al. "Structural and Social Determinants of Health Factors Associated with County-Level Variation in Non-Adherence to Antihypertensive Medication Treatment." International Journal of Environmental Research and Public Health 17, no. 18 (September 14, 2020): 6684. http://dx.doi.org/10.3390/ijerph17186684.

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Background: Non-adherence to antihypertensive medication treatment (AHM) is a complex health behavior with determinants that extend beyond the individual patient. The structural and social determinants of health (SDH) that predispose populations to ill health and unhealthy behaviors could be potential barriers to long-term adherence to AHM. However, the role of SDH in AHM non-adherence has been understudied. Therefore, we aimed to define and identify the SDH factors associated with non-adherence to AHM and to quantify the variation in county-level non-adherence to AHM explained by these factors. Methods: Two cross-sectional datasets, the Centers for Disease Control and Prevention (CDC) Atlas of Heart Disease and Stroke (2014–2016 cycle) and the 2016 County Health Rankings (CHR), were linked to create an analytic dataset. Contextual SDH variables were extracted from the CDC-CHR linked dataset. County-level prevalence of AHM non-adherence, based on Medicare fee-for-service beneficiaries’ claims data, was extracted from the CDC Atlas dataset. The CDC measured AHM non-adherence as the proportion of days covered (PDC) with AHM during a 365 day period for Medicare Part D beneficiaries and aggregated these measures at the county level. We applied confirmatory factor analysis (CFA) to identify the constructs of social determinants of AHM non-adherence. AHM non-adherence variation and its social determinants were measured with structural equation models. Results: Among 3000 counties in the U.S., the weighted mean prevalence of AHM non-adherence (PDC < 80%) in 2015 was 25.0%, with a standard deviation (SD) of 18.8%. AHM non-adherence was directly associated with poverty/food insecurity (β = 0.31, P-value < 0.001) and weak social supports (β = 0.27, P-value < 0.001), but inversely with healthy built environment (β = −0.10, P-value = 0.02). These three constructs explained one-third (R2 = 30.0%) of the variation in county-level AHM non-adherence. Conclusion: AHM non-adherence varies by geographical location, one-third of which is explained by contextual SDH factors including poverty/food insecurity, weak social supports and healthy built environments.

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Cabello, M., J. A. G. Orza, and V. Galiano. "Air mass origin and its influence over the aerosol size distribution: a study in SE Spain." Advances in Science and Research 2, no. 1 (May 13, 2008): 47–52. http://dx.doi.org/10.5194/asr-2-47-2008.

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Abstract. A k-means cluster analysis of 96 hour trajectories arriving in Southeast (SE) Spain at 3000, 1500 and 500 m for the 7-year period 2000–2006 has been performed to identify and describe the main flows arriving at the study area. The dependence of the aerosol size distribution on the air mass origin has been studied by using non-parametric statistics. There are statistically significant differences on aerosol size distribution and meteorological variables at surface level according to the identified clusters.

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Bonnafous, Fanny, Ghislain Fievet, Nicolas Blanchet, Marie-Claude Boniface, Sébastien Carrère, Jérôme Gouzy, Ludovic Legrand, et al. "Comparison of GWAS models to identify non-additive genetic control of flowering time in sunflower hybrids." Theoretical and Applied Genetics 131, no. 2 (November 2, 2017): 319–32. http://dx.doi.org/10.1007/s00122-017-3003-4.

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Nordbotten, Gerd L., Leif I. Tjelta, and Merete H. Helland. "Maintenance of weight loss and aerobic capacity one year aft er the end of a lifestyle intervention focusing on nutritional guidance and/or exercise." Acta Kinesiologiae Universitatis Tartuensis 25 (January 3, 2020): 19–36. http://dx.doi.org/10.12697/akut.2019.25.02.

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The aims of this study were to: 1) investigate to what extent participants in a lifestyle intervention program, including nutritional guidance and two weekly intensive running sessions, maintain improvements in aerobic capacity and health parameters one year after the end of an intervention; and 2) identify common determinants for those participants who succeeded in weight loss maintenance. A total of 51 participants completed the 33-week intervention. One year after the end of the intervention period (1YA) 34 participants completed anthropometric measurements, 12 (8 women) in the training group (TG) and 22 (13 women) in the nutritional guidance and training group (NTG). A total of 13 participants (9 women) in the TG and 11 participants (7 women) in the NTG completed a 3000 m running test. There were no significant differences in body mass index, 3000 m running time or waist circumference between the groups 1YA. There was however, substantial variation in both groups as to what extent participants had maintained their weight loss. Higher self-efficacy and self-control in relation to food and exercise characterized those who best maintained their weight loss.

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Idayanti, Iik, and Hadira Latiar. "KEPEGAWAIAN DI KESULTANAN SIAK: GAMBARAN ARSIP GAJI ERA SULTAN SYARIF KASIM II." Jurnal Kearsipan 15, no. 1 (June 30, 2020): 63–78. http://dx.doi.org/10.46836/jk.v15i1.150.

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The salary archive used in this study is a digital archive owned by the Siak Regency Library and Archives Office. The archive is a legacy of Sultan Syarif Kasim II's government (1915-1945). There are 3000 archives available. At present, there are not many writings that reveal the contents of this historical value archive, especially those relating to staffing, whereas in this historical archive there is a description of the sultan's policies in the welfare of his people. The purpose of this research is to identify and provide archival description relating to employee salaries. The method applied in this study is qualitative with a descriptive approach. The results showed that of the 3000 digital archives, 280 of them contained salary information for 100 employees. The identified file illustrates 3 things, namely the monitoring of the Colonial Government which was shown in the use of two languages in the archive, namely Malay and Dutch; The government sistem is centralized, because direct employment is responsible to the Sultan; The Sultan appreciates the ability and service of his employees, this is reflected in the difference in salary received by each employee based on his tenure.

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Li, Pingyuan, Mingkun Li, Huayang Gan, and Zhen Xia. "A preliminary study on sediment records of possible typhoon in the northern South China Sea during the past 6500 years." Holocene 31, no. 7 (April 12, 2021): 1221–28. http://dx.doi.org/10.1177/09596836211003229.

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Typhoon is an important meteorological phenomenon that affects the living and development of human beings on the southern China coast. However, there is still lack of clarity in the paleo-typhoon history and its influence on the evolution of the ancient human settlement environment since the mid-Holocene. Here, we identify six typhoon-like deposits from a core retrieved from the northern South China Sea shelf, close to the Pearl River Estuary, based on accelerated mass spectrometry 14C dating, grain size, and geochemistry. The sand fractions, CaO, Sr, SiO2/TiO2, and SiO2/Al2O3 were used to indicate the typhoon-like deposits. Results show that the ages with high-frequency typhoons are present ~200–300 cal yr BP, ~800–1000 cal yr BP, ~1500–1700 cal yr BP, ~2000–2100 cal yr BP, ~2400–2500 cal yr BP, and ~2700–3000 cal yr BP. Our results are comparable to the records from adjacent regions. Significantly, the vast tides occurred in the duration of ~2700–3000 cal yr BP in southern China, which probably caused the ancestors’ migration to the inland. Further studies are needed to deeply study the paleo-typhoon history in the southern China coast to verify our results.

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Hugosson, J. "Can MRI identify prostate cancer in men with PSA less than 3 ng/ml?" European Urology Supplements 15, no. 2 (January 2016): 27. http://dx.doi.org/10.1016/s1569-9056(16)30001-x.

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Barta, Tamás. "The examination of roe deer feeding on agricultural and woody habitats in winter." Acta Agraria Debreceniensis, no. 31 (November 24, 2008): 23–26. http://dx.doi.org/10.34101/actaagrar/31/3000.

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sorting because the micro organisms, which help the digestion of high fibre plants, are missing in his stomack, that is why they are mostly called „concentrate selectors” (Hoffmann, 1985, 1988, 1989).These animals should mostly eat easily digestable plants with high nutrition level (pulses, buds, sprouts and flowers), and they are able to do this sorting because of their mouth size. In winter there is a lack of these plants, so the high selectivity occurs only when the feed is in abbundance.Examining the amount and quality of vegetation available on the habitat of roe deer we can identify the species which can satisfy their feed demand. It is known, that roe deer as other large ruminants, from the plant abundance prefer certain plants and plant parts while there are others which are avoided. The identification of the eaten species and the rate of their occurrence in the feed is the first step to become acquainted with the interaction between animal and the surroundings.On the examined territories there was significant difference between the disembowelled body masses. The does which come from the hunt Nagyszénás weighed 4-5 kilos more than the does from the Csongrád territory. The main feed components were present in different rate in the samples of the territories, in the Nagyszénás samples grain, dicotyledonous herbacous plants were dominant, and were eaten more. The high level of grain in the feed result in better condition and larger body mass.

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De Silva, Kushan, Daniel Jönsson, and Ryan T. Demmer. "A combined strategy of feature selection and machine learning to identify predictors of prediabetes." Journal of the American Medical Informatics Association 27, no. 3 (December 30, 2019): 396–406. http://dx.doi.org/10.1093/jamia/ocz204.

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Abstract Objective To identify predictors of prediabetes using feature selection and machine learning on a nationally representative sample of the US population. Materials and Methods We analyzed n = 6346 men and women enrolled in the National Health and Nutrition Examination Survey 2013–2014. Prediabetes was defined using American Diabetes Association guidelines. The sample was randomly partitioned to training (n = 3174) and internal validation (n = 3172) sets. Feature selection algorithms were run on training data containing 156 preselected exposure variables. Four machine learning algorithms were applied on 46 exposure variables in original and resampled training datasets built using 4 resampling methods. Predictive models were tested on internal validation data (n = 3172) and external validation data (n = 3000) prepared from National Health and Nutrition Examination Survey 2011–2012. Model performance was evaluated using area under the receiver operating characteristic curve (AUROC). Predictors were assessed by odds ratios in logistic models and variable importance in others. The Centers for Disease Control (CDC) prediabetes screening tool was the benchmark to compare model performance. Results Prediabetes prevalence was 23.43%. The CDC prediabetes screening tool produced 64.40% AUROC. Seven optimal (≥ 70% AUROC) models identified 25 predictors including 4 potentially novel associations; 20 by both logistic and other nonlinear/ensemble models and 5 solely by the latter. All optimal models outperformed the CDC prediabetes screening tool (P < 0.05). Discussion Combined use of feature selection and machine learning increased predictive performance outperforming the recommended screening tool. A range of predictors of prediabetes was identified. Conclusion This work demonstrated the value of combining feature selection with machine learning to identify a wide range of predictors that could enhance prediabetes prediction and clinical decision-making.

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Feeser, Ingo, Walter Dörfler, Jutta Kneisel, Martin Hinz, and Stefan Dreibrodt. "Human impact and population dynamics in the Neolithic and Bronze Age: Multi-proxy evidence from north-western Central Europe." Holocene 29, no. 10 (June 27, 2019): 1596–606. http://dx.doi.org/10.1177/0959683619857223.

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This paper aims at reconstructing the population dynamics during the Neolithic and Bronze Age, c. 4500–500 cal. BC, in north-western Central Europe. The approach is based on the assumption that increased population density is positively linked with human activity and human impact on the environment, respectively. Therefore, we use archaeological 14C dates and palaeoenvironmental data from northern Germany and south-western Denmark to construct and compare independent proxies of human activity. The latter involves relative quantification of human impact based on pollen analysis and soil erosion history inferred from summarizing of dated colluvial layers. Concurring patterns of changes in human activity are frequently recorded on a multi-centennial scale. Whereas such multi-proxy patterns are interpreted to indicate relative population changes, divergent patterns are discussed in the context of proxy-related uncertainties and potential biases. Patterns of temporal distribution of increasing and decreasing human activity are understood as ‘boom and bust’ phases in population density/size. Based on the comparison of the three proxies, we identify five phases of growing (boom) and four phases of decreasing (bust) population. The boom phases date to ca. 4000–3500, 3000–2900, 2200–2100, 1450–1300 and 1000–750 cal. BC. The bust phases to ca. 3200–3000, 2400–2300, 1650–1500 and 1200–1100 cal. BC.

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Biesse, Frédéric, Jérôme Mahé, and Nicolas Lévy. "Average Worn Profile of Tires in Europe." Tire Science and Technology 42, no. 3 (July 1, 2014): 166–84. http://dx.doi.org/10.2346/tire.14.420303.

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ABSTRACT Tire tread wear is a key issue in the tire development process and for tire customers. In order to measure the wear performance, tire manufacturers usually proceed to wear tests and calculate the tire life from those tests. An important point in this tire life computation is the criteria chosen for defining the tire's end of life. In Europe, there is a legal minimum tread depth set to 1.6 mm applicable to 75% of the tread pattern width. However, outside those 75% (i.e., on the shoulder part), no clear and shared limit is defined. Also, the usual behavior of customers to decide when their tires should be changed is not well known. The goal of this 2012 study was to identify an average worn profile of tires in Europe and the behavior of customers for replacing their tires. For that, 3000 tires worn out by customers have been collected in scrapyards and measured in five European countries. In this article, we will present the tire collecting method, the measurement process, the analysis method, and some general results and statistics on this 3000 tire database. Finally, the method to compute the average end of life profile and the resulting profile is given.

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KASUYA, A., H. IWASAKI, Y. SAITO, M. OKUDA, H. TAKAHASHI, M. SUEZAWA, K. SUMIYAMA, K. SUZUKI, and Y. NISHINA. "MAGNETIC MEASUREMENTS ON YC2 ENCAPSULATED IN GRAPHITIC POLYHEDRAL PARTICLES." Surface Review and Letters 03, no. 01 (February 1996): 853–55. http://dx.doi.org/10.1142/s0218625x96001534.

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Graphitic polyhedrons encaging YC 2 of 30–70 nm in diameter have been synthesized by an arc-discharge method. Our measurements identify that YC 2 crystallizes in a body-centered tetragonal and becomes type-II superconductor below 3.9 K. The transition temperature shows very small size dependence, and is nearly equal to previous measurements on bulk YC 2 in vacuum. Although YC 2 is hygroscopic, our samples yield reliable and reproducible experimental results in our electron microscope, x-ray diffraction, paramagnetic resonance, and magnetization measurements in air under magnetic field up to 3000 Oe and temperatures down to 1.7 K.

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Rodríguez-Salazar, María Clara, and Ángela Patricia Valero-Ballesteros. "Efecto de una intervención Act sobre la resistencia aeróbica y evitación experiencial en marchistas / Effect of an ACT Intervention on Aerobic Endurance and Experiential Avoidance in Walkers." Revista Costarricense de Psicología 34, no. 2 (December 16, 2015): 97. http://dx.doi.org/10.22544/rcps.v34i02.04.

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Resumen:El presente estudio tuvo como propósito identificar el efecto de la intervención en Terapia de Aceptación y Compromiso (ACT) sobre la resistencia aeróbica y conducta de evitación experiencial en un grupo de marchistas de Bogotá. Se utilizó un diseño pretest-postest con grupo control. La muestra estuvo compuesta por diez marchistas de ambos sexos, con un promedio de edad de 16.70 y un rango entre los 15 y 20 años de edad, pertenecientes a la Liga de Atletismo de Bogotá. Se eligieron por conveniencia. Se emplearon como instrumentos de medición el test de los 3000 m y el Cuestionario de Aceptación Acción (AAQ). La intervención en ACT se realizó en cuatro sesiones en las que se desarrollaron los contenidos definidos por los autores de la intervención (Wilson y Luciano, 2002). Para el análisis de los datos, se empleó estadística no paramétrica a través de la prueba U de Mann-Whitney. Los resultados señalan una mayor resistencia aeróbica en la prueba de los 3000 m en el postest del grupo experimental con respecto al grupo control, así como una mayor aceptación de los eventos internos negativos. Abstract:The purpose of the present study was to identify the effect of an Acceptance and Commitment intervention Therapy (ACT) on aerobic endurance and experiential avoidance behavior of a group of walkers in Bogota. This study used a pretest-posttest design with a control group. The sample consisted of ten walkers of either sex, with an average age of 16.70 years, and a range between 15 and 20 years old, belonging to the Bogotá Athletics League. The participants were chosen as a convenience sample. The instruments used were the 3000-meter test and the Acceptance and Action Questionnaire (AAQ). The ACT intervention was conducted in four sessions, where they developed the contents defined by the authors of this intervention (Wilson and Luciano, 2002). Non-parametric statistics were used for data analysis, by means of the Mann-Whitney U. The posttest results indicate a greater aerobic resistance in the 3000-meter test for the test group in comparison to the control group. Likewise the experimental group shows a greater acceptance for negative internal events.

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Costa, Ricardo Diniz da, and John Starkey. "PhotoLin: a program to identify and analyze linear structures in aerial photographs, satellite images and maps." Computers & Geosciences 27, no. 5 (June 2001): 527–34. http://dx.doi.org/10.1016/s0098-3004(00)00146-1.

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Rush, Janet P., Larry W. Chambers, and Wayne Keddy. "A Study To Identify Who Is the Responsible Physician for Each Patient in a Teaching Hospital." QRB - Quality Review Bulletin 12, no. 12 (December 1986): 426–30. http://dx.doi.org/10.1016/s0097-5990(16)30090-2.

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Peters, Susan, Leonard van den Berg, Jan Veldink, and Roel Vermeulen. "O6E.6 Occupational exposures and ALS: international collaborations and new ways to identify risk factors." Occupational and Environmental Medicine 76, Suppl 1 (April 2019): A61.1—A61. http://dx.doi.org/10.1136/oem-2019-epi.163.

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BackgroundAssociations between occupational exposures and amyotrophic lateral sclerosis (ALS) have been suggested, but results are inconsistent. Case-control studies are best suited for inclusion of clinically confirmed incident cases, but prone to recall bias. Cohort studies are free from recall bias and may have pre-symptomatic blood stored, to inform about exposures (e.g. lead) well before disease onset.MethodsAn ongoing nation-wide ALS case-control study has been conducted in the Netherlands since 2006 (currently over 3000 cases and 4500 controls) to study risk factors and possible gene-environment interactions. Part of this study has been pooled with case-control studies from Ireland and Italy (Euro-MOTOR), where the same questionnaire was administered.ResultsWithin the Euro-MOTOR study, ∼1300 cases and ∼2600 controls had full job histories available. Occupational exposures to a range of agents were assessed using job-exposure matrices. Analyses were adjusted for age, sex, centre, education, smoking and alcohol. We found significant associations between ALS and exposure to silica (OR 1.73, 95% CI 1.28–2.33), extremely low-frequency magnetic fields (OR 1.16, 95% CI 1.01–1.33) and electric shocks (OR 1.23, 95% CI 1.05–1.43), independent of the other occupational exposures studied.Future perspectivesA nested ALS case-control study was conducted within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. 219 people who died from ALS have been identified, and pre-symptomatic blood samples from 168 of these cases are available for analyses. Three controls per case were selected by incidence density sampling matched by age at recruitment, sex and study centre. Metal concentrations will be analysed in the erythrocytes. This would be the first prospective study on the association between exposure to metals and ALS.ConclusionEach study design has its strengths and weaknesses, and ALS should be investigated in a range of (occupational) studies to gain better understanding of its aetiology.

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Doucette, Lance P., Nicole C. L. Noel, Yi Zhai, Manlong Xu, Oana Caluseriu, Stephanie C. Hoang, Alina J. Radziwon, and Ian M. MacDonald. "Whole exome sequencing reveals putatively novel associations in retinopathies and drusen formation." European Journal of Human Genetics 29, no. 8 (March 29, 2021): 1171–85. http://dx.doi.org/10.1038/s41431-021-00872-3.

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AbstractInherited retinal dystrophies (IRDs) affect 1 in 3000 individuals worldwide and are genetically heterogeneous, with over 270 identified genes and loci; however, there are still many identified disorders with no current genetic etiology. Whole exome sequencing (WES) provides a hypothesis-free first examination of IRD patients in either a clinical or research setting to identify the genetic cause of disease. We present a study of IRD in ten families from Alberta, Canada, through the lens of novel gene discovery. We identify the genetic etiology of IRDs in three of the families to be variants in known disease-associated genes, previously missed by clinical investigations. In addition, we identify two potentially novel associations: LRP1 in early-onset drusen formation and UBE2U in a multi-system condition presenting with retinoschisis, cataracts, learning disabilities, and developmental delay. We also describe interesting results in our unsolved cases to provide further information to other investigators of these blinding conditions.

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Soria, Jean-Charles, Hui Kong Gan, Hendrik-Tobias Arkenau, Sarah Patricia Blagden, Ruth Plummer, Malcolm Ranson, T. R. Jeffry Evans, et al. "Phase I clinical and pharmacologic study of the focal adhesion kinase (FAK) inhibitor GSK2256098 in pts with advanced solid tumors." Journal of Clinical Oncology 30, no. 15_suppl (May 20, 2012): 3000. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.3000.

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3000 Background: FAK has an important role in cancer invasion and metastasis. FAK and phospho-FAK (pFAK) are increased in advanced cancer and are correlated with poor prognosis. GSK2256098 is a potent and specific small molecule inhibitor of FAK. Methods: This is a first-time in cancer pts, dose escalation study (NCT01138033) to identify the maximum tolerated dose (MTD), safety, pharmacokinetics (PK), pharmacodynamics (PD), and clinical activity. Part 1 used a modified accelerated titration procedure switching to standard 3+3 design based on toxicity during the first 21 days of treatment. Pts were treated with GSK2256098 orally twice daily (BID) with food. Safety was established in cohorts of 1-6 pts. After MTD determination, Parts 2 and 3 were opened to further evaluate safety, PK and PD. Serial PK samples were obtained over 24 h on Days 1 and 15. Pre- and post-dose skin, hair and tumor tissue biopsies were analyzed for pFAK. Results: 57 pts with advanced solid tumors have been treated at escalating doses ranging from 80 mg to 1500 mg BID: median age=58.8 (range 21-84). The most common tumor types include: mesothelioma (23), ovary (7), colon (3), kidney (3), and pancreas (3). MTD was determined to be 1000 mg BID. DLTs were Gr 2 proteinuria (1000 mg), Gr 2 nausea, vomiting, fatigue (1250 mg) and Gr 3 asthenia (1500 mg). Most frequent toxicities were nausea (32 pts, 56%), diarrhea (31 pts, 54%), vomiting (25 pts, 44%), decreased appetite (18 pts 32%) and asthenia (11 pts, 19%). The majority of toxicities were Gr 1-2; Gr 3 drug-related events included hypertriglyceridemia (n=2), hyperlipasemia (2), asthenia (1), increased amylase (1), and loss of consciousness (1). Few dose reductions and interruptions have occurred. Minor responses/stable disease (SD) were observed in pts with mesothelioma (-12%, 27 wks), melanoma (-26%, 54 wks), and naso/pharyngeal cancer (-31% target lesion, 30 wks) and SD in renal cell (48+ wks). In preliminary analysis of single-dose PK, exposure generally increased in a dose-proportional manner, and the geometric mean t½ was 4.2 h. Accumulation was not observed with repeat dosing. Conclusions: GSK2256098 is well tolerated with evidence of clinical activity. PK supports BID dosing.

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Sealey, Katrina M., Michael J. Drinkwater, Mike J. Irwin, and John K. Webb. "The Red Bright Quasar Survey (RBQS)." International Astronomical Union Colloquium 148 (1995): 522–27. http://dx.doi.org/10.1017/s0252921100022466.

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AbstractWe are using the UK Schmidt telescope (UKST) to carry out a new objective prism survey, covering 2000-3000 square degrees of high galactic latitude sky in the equatorial region. The survey is targeted at discovering both bright (R < 18) quasars in general and bright high redshift (2 < z < 4) quasars in particular, which will be valuable for high resolution spectroscopic follow-up studies. We are using a mixture of ultra-violet excess (XJVX) and a new template matching technique to identify all the bright quasars. Details of the project are discussed and some preliminary results of the survey are presented.

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Månsson, Sara, Kristin Davidsson, Patrick Lauenburg, and Marcus Thern. "Automated Statistical Methods for Fault Detection in District Heating Customer Installations." Energies 12, no. 1 (December 29, 2018): 113. http://dx.doi.org/10.3390/en12010113.

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In order to develop more sustainable district heating systems, the district heating sector is currently trying to increase the energy efficiency of these systems. One way of doing so is to identify customer installations in the systems that have poor cooling performance. This study aimed to develop an algorithm that was able to detect the poorly performing installations automatically using meter readings from the installations. The algorithm was developed using statistical methods and was tested on a data set consisting of data from 3000 installations located in a district heating system in Sweden. As many as 1273 installations were identified by the algorithm as having poor cooling performance. This clearly shows that it is of major interest to the district heating companies to identify the installations with poor cooling performance rapidly and automatically, in order to rectify them as soon as possible.

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Cotlarciuc, Ioana, Muhammad Saleem Khan, Ankita Maheshwari, Sunaina Yadav, Fahmi Yousif Khan, H. Al-Hail, Ranil De Silva, et al. "Bio-repository of DNA in stroke: a study protocol of three ancestral populations." JRSM Cardiovascular Disease 1, no. 4 (July 2012): 1–8. http://dx.doi.org/10.1258/cvd.2012.012019.

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Stroke is a leading cause of death and disability in the world. Identifying the genes underlying stroke risk may help us to improve our understanding of the mechanisms that cause stroke and also identify novel therapeutic targets. To have sufficient power to disentangle the genetic component of stroke, large-scale highly phenotyped DNA repositories are necessary. The BRAINS (Bio-repository of DNA in stroke) study aims to recruit subjects with all subtypes of stroke as well as controls from UK, India, Sri Lanka and Qatar. BRAINS-UK will include 1500 stroke patients of European ancestry as well as British South Asians. BRAINS-South Asia aims to recruit 3000 stroke subjects and 3000 controls from across India and Sri Lanka. BRAINS-Middle East aims to enrol 1500 stroke patients from Qatar. The controls for BRAINS-Middle East will be recruited from a population-based Qatari Biobank. With the addition of new recruitment centres in India and Qatar, we present an updated version of the BRAINS study protocol. This is the first international DNA biobank for stroke patients and controls from the Middle East. By investigating the influence of genetic factors on stroke risk in European, South Asian and Middle Eastern populations, BRAINS has the potential to improve our understanding of genetic differences between these groups and may lead to new population-specific therapeutic targets.

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Vargas, José Eduardo, Nadine Kubesch, Carles Hernandéz-Ferrer, Glória Carrasco-Turigas, Mariona Bustamante, Mark Nieuwenhuijsen, and Juan R. González. "A systemic approach to identify signaling pathways activated during short-term exposure to traffic-related urban air pollution from human blood." Environmental Science and Pollution Research 25, no. 29 (August 23, 2018): 29572–83. http://dx.doi.org/10.1007/s11356-018-3009-8.

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Kim, Tae Won, Jeeyun Lee, Sang Joon Shin, Jin-Soo Kim, Yu Jung Kim, Hye Sook Han, Soo Jung Lee, et al. "Belvarafenib, a novel pan-RAF inhibitor, in solid tumor patients harboring BRAF, KRAS, or NRAS mutations: Phase I study." Journal of Clinical Oncology 37, no. 15_suppl (May 20, 2019): 3000. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.3000.

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3000 Background: Belvarafenib (HM95573/GDC-5573) is an oral type II pan-RAF kinase inhibitor which demonstrates selective anti-tumor activity in several non-clinical cancer models and in cancer patients with RAS- or RAF- mutation. Here we present overall safety and efficacy findings of two phase 1 studies, consisting of dose escalation and dose expansion stages. Methods: Patients with advanced solid cancers harboring documented RAS- or RAF- mutation were enrolled. In the dose escalation study, patients were treated with Belvarafenib at a starting dose of 50 mg once daily (QD) to 800 mg BID to assess safety and tolerability and identify the recommended dose (RD). Dose escalation was guided based on pharmacokinetic data and used a traditional 3+3 design. The dose expansion study was comprised of 6 cohorts (according to the type of tumor and RAS- or RAF gene mutation) and patients received the RD of Belvarafenib. The primary objective was to explore anti-tumor activity (per RECIST 1.1) and pharmacodynamic effects. Results: The dose escalation study included 72 patients in 9 dose cohorts (cut-off date of 18 Jan 2017). Dose dependent increase in exposures observed up to 650 mg BID. The most common treatment-emergent adverse events that occurred in more than 20% of patients were rash, dermatitis acneiform and pyrexia. A total of 4 DLTs (different kinds of rashes) were reported and included 2 DLTs at the 800 mg BID level. Therefore, 650 mg BID was considered the MTD and 450 mg BID was identified as the RD for Belvarafenib. There were 7 partial responses (3 confirmed PRs) from 200 mg QD to 800 mg BID in NRAS-mutant melanoma, BRAF-mutant melanoma, KRAS-mutant sarcoma, and BRAF-mutant GIST. Four of nine patients with NRAS-mutant melanoma had a PR (ORR 44%). The dose expansion study included 63 patients in 5 indication-specific and basket cohorts administered with 450 mg BID Belvarafenib (cut-off date of 6 Oct 2018). No new safety signal was detected. There were two PRs each in patients with NRAS-mutant melanoma (2/9), BRAF-mutant melanoma (2/6) and BRAF-mutant CRC (2/7), respectively. Conclusions: Belvarafenib was well tolerated and exhibited anti-tumor activity in patients with advanced solid tumors harboring RAS or RAF mutations. Belvarafenib is being further investigated in combination with the MEK inhibitor cobimetinib. Clinical trial information: NCT02405065, NCT03118817.

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Mahale, Vivek N., Guifu Zhang, and Ming Xue. "Fuzzy Logic Classification of S-Band Polarimetric Radar Echoes to Identify Three-Body Scattering and Improve Data Quality." Journal of Applied Meteorology and Climatology 53, no. 8 (August 2014): 2017–33. http://dx.doi.org/10.1175/jamc-d-13-0358.1.

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AbstractThe three-body scatter signature (TBSS) is a radar artifact that appears downrange from a high-radar-reflectivity core in a thunderstorm as a result of the presence of hailstones. It is useful to identify the TBSS artifact for quality control of radar data used in numerical weather prediction and quantitative precipitation estimation. Therefore, it is advantageous to develop a method to automatically identify TBSS in radar data for the above applications and to help identify hailstones within thunderstorms. In this study, a fuzzy logic classification algorithm for TBSS identification is developed. Polarimetric radar data collected by the experimental S-band Weather Surveillance Radar-1988 Doppler (WSR-88D) in Norman, Oklahoma (KOUN), are used to develop trapezoidal membership functions for the TBSS class of radar echo within a hydrometeor classification algorithm (HCA). Nearly 3000 radar gates are removed from 50 TBSSs to develop the membership functions from the data statistics. Five variables are investigated for the discrimination of the radar echo: 1) horizontal radar reflectivity factor ZH, 2) differential reflectivity ZDR, 3) copolar cross-correlation coefficient ρhv, 4) along-beam standard deviation of horizontal radar reflectivity factor SD(ZH), and 5) along-beam standard deviation of differential phase SD(ΦDP). These membership functions are added to an HCA to identify TBSSs. Testing is conducted on radar data collected by dual-polarization-upgraded operational WSR-88Ds from multiple severe-weather events, and results show that automatic identification of the TBSS through the enhanced HCA is feasible for operational use.

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Calais, Jérémie, Bernard Dubray, Lamyaa Nkhali, Sebastien Thureau, Charles Lemarignier, Romain Modzelewski, Isabelle Gardin, Frederic Di Fiore, Pierre Michel, and Pierre Vera. "High FDG uptake areas on pre-radiotherapy PET/CT identify preferential sites of local relapse after chemoradiotherapy for locally advanced oesophageal cancer." European Journal of Nuclear Medicine and Molecular Imaging 42, no. 6 (February 14, 2015): 858–67. http://dx.doi.org/10.1007/s00259-015-3004-y.

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Prathapar, S. A., W. S. Meyer, J. C. Madden, and E. Alociljá. "SWAGMAN Options: A hierarchical multicriteria framework to identify profitable land uses that minimize water table rise and salinization." Applied Mathematics and Computation 83, no. 2-3 (May 1997): 217–40. http://dx.doi.org/10.1016/s0096-3003(96)00186-5.

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Sucularli, C., H. Kocak, and C. E. Keegan. "111 High-throughput gene expression analysis to identify P53-dependent and -independent mechanisms contributing to the acd phenotype." European Journal of Cancer 51 (September 2015): S4. http://dx.doi.org/10.1016/s0959-8049(16)30009-0.

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Crognier, E. "Child mortality and society in Morocco." Journal of Biosocial Science 19, no. 2 (April 1987): 127–37. http://dx.doi.org/10.1017/s0021932000016722.

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SummaryMultivariate (correspondence) analysis is employed to identify socioeconomic factors affecting fertility and infant mortality in Marrakesh (Morocco), using questionnaire data from some 3000 women attending 20 dispensaries in different parts of the city. Factors of the material environment (availability of water and electricity in the residence), size of household and number of wage earners in it are pervasive and suggest a polarity between archaic elements in the society (low material comfort, polygyny, absence of contraception) and the more forward looking (monogamy, tertiary occupations). Fertility and child mortality variations reflect this polarity. The differences that occur among the 20 dispensaries direct attention to the neighbourhoods where public health measures may be expected to be most effective and rewarding.

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Rai, Himanshu, Roshni Khare, Rajan Kumar Gupta, and Dalip Kumar Upreti. "Terricolous lichens as indicator of anthropogenic disturbances in a high altitude grassland in Garhwal (Western Himalaya), India." Botanica Orientalis: Journal of Plant Science 8 (March 2, 2012): 16–23. http://dx.doi.org/10.3126/botor.v8i0.5554.

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Lichens are known to be more sensitive indicators of ecosystem functioning and disturbances than any other cryptogams and vascular plant communities. Himalayan habitats, despite their stressed climates, harbor some of the unique biodiversity of the region, vital for overall ecosystem functioning and stability. Lichens, due to their desiccation tolerance, are able to survive in high altitude habitats and evolved into diverse categories and functional groups. Present study examines the terricolous lichen community in Chopta-Tungnath temperate-alpine grassland of Garhwal Himalaya, in order to identify potential elements (species/growth form) as indicator of anthropogenic disturbances. Terricolous lichens were sampled from twelve sites distributed in three stratified macrohabitats, along increasing altitudinal gradient. A total of twenty soil lichen species belonging to ten genera, six families and four morphological groups (i.e. leprose, foliose, dimorphic and fruticose) were identified. Terricolous lichen diversity was negatively correlated (r = 0.70; p<0.05) with altitude. Among the four growth forms, fruticose growth form was indicator of grazing disturbance, distinguishing low grazed high altitude (3400-4001 m asl) areas with highly grazed low altitude (2700-3000 m asl) to mid altitude (3000-3400 m asl) areas. Terricolous lichen diversity in the study area was found constrained by vascular plants at lower altitudes, human-related impacts (tourism and livestock grazing induced trampling) at mid-altitudes and habitat characteristics (low soil cover) at higher altitudes.doi: http://dx.doi.org/10.3126/botor.v8i0.5554 Botanica Orientalis – Journal of Plant Science (2011) 8: 16-23

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Huljannah, Miftah, Fitra Ayu Lestari, and Tomi Erfando. "Preliminary Study on The Utilization Of Seaweed and Green Grass Jelly Leaves as Candidate Alternatives for EOR Polymer." TEKNIK 41, no. 3 (November 18, 2020): 246–52. http://dx.doi.org/10.14710/teknik.v41i3.28148.

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The declining in production can occur because wells that have been producing for a long time are no longer able to lift oil to the surface in primary and secondary ways. Therefore, tertiary methods such as chemical injection like polymer flooding were carried out. Polymers commonly used in flooding polymers are divided into three namely synthetic polymers, biopolymers, and natural polymers. Natural polymers have abundant sources such as seaweed and grass jelly. This study was aimed to identify alternative renewable polymers as flooding polymer materials by knowing initial characteristics such as viscosity, compatibility and the effect of shear rates. This test wass carried out by an experimental method with several stages, namely drying, crushing to powder, and making polymers that were dissolved into brines that have different salinity. Then the polymer was allowed to stand for more than 24 hours until it was tested. The material tested was seaweed, grass jelly, and biopolymer xanthan gum as a comparison. The parameters used are polymer concentrations of 1000 ppm, 2000 ppm and 3000 ppm with each salinity of 3000 ppm, 9000 ppm and 15000 ppm. The test results showed that the characteristics of natural polymers were the same as biopolymers, the viscosity decreased as the brines salinity increased .The absence of sedimentation resulted from Seaweed and grass jelly solution and formation water indicated that the polymers had good compatibility and shear rate test has shown that the polymers are psuodoplastic.

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Bennett, Ryan P., Courtney L. Finch, Elena N. Postnikova, Ryan A. Stewart, Yingyun Cai, Shuiqing Yu, Janie Liang, et al. "A Novel Ebola Virus VP40 Matrix Protein-Based Screening for Identification of Novel Candidate Medical Countermeasures." Viruses 13, no. 1 (December 31, 2020): 52. http://dx.doi.org/10.3390/v13010052.

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Filoviruses, such as Ebola virus and Marburg virus, are of significant human health concern. From 2013 to 2016, Ebola virus caused 11,323 fatalities in Western Africa. Since 2018, two Ebola virus disease outbreaks in the Democratic Republic of the Congo resulted in 2354 fatalities. Although there is progress in medical countermeasure (MCM) development (in particular, vaccines and antibody-based therapeutics), the need for efficacious small-molecule therapeutics remains unmet. Here we describe a novel high-throughput screening assay to identify inhibitors of Ebola virus VP40 matrix protein association with viral particle assembly sites on the interior of the host cell plasma membrane. Using this assay, we screened nearly 3000 small molecules and identified several molecules with the desired inhibitory properties. In secondary assays, one identified compound, sangivamycin, inhibited not only Ebola viral infectivity but also that of other viruses. This finding indicates that it is possible for this new VP40-based screening method to identify highly potent MCMs against Ebola virus and its relatives.

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Chulay, Marianne. "Good Research Ideas for Clinicians." AACN Advanced Critical Care 17, no. 3 (July 1, 2006): 253–65. http://dx.doi.org/10.4037/15597768-2006-3004.

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While the conduct of nursing research is an important professional value, it is an activity rarely performed by nurses employed in the service setting. Whether the reason is a lack of commitment to a scientific basis for nursing practice or an inability to operationalize the research process in the clinical setting, the outcome is a dearth of clinically relevant studies to guide patient care. Clinicians must be involved in asking and answering clinically relevant questions to maximize patient outcomes. This article provides suggestions to assist clinicians to identify the types of clinical questions that are most likely to result in successful completion of research projects by busy, service-setting clinicians. Strategies are described that will assist clinicians to identify research questions of relevance to their practice areas.

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Fumia, Doreen. "Divides, High Rise and Boundaries." Ethnologies 32, no. 2 (September 15, 2011): 257–89. http://dx.doi.org/10.7202/1006312ar.

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Acts of domination are not always easy to identify, and in hindsight, the best intentions of post WWII rezoning and “arden city”high-rise developments have not served poor, racialized immigrants well. While the poor in the Downtown East Side of Toronto did not benefit from postwar urban renewal, the middle classes did, but only because they mustered resources in order to block zoning that would allow high rises. As a result, one area of the DTES is one of the most condensed stocks of beautifully preserved Victorian-style homes in Canada. This article interrogates the postwar rationalization of the DTES and the claim, and the resistance to it, that it is “ot the right for 3000 poor people to live downtown”.

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Gabrielli, P., G. Cozzi, S. Torcini, P. Cescon, and C. Barbante. "Source and origin of atmospheric trace elements entrapped in winter snow of the Italian Eastern Alps." Atmospheric Chemistry and Physics Discussions 6, no. 5 (September 19, 2006): 8781–815. http://dx.doi.org/10.5194/acpd-6-8781-2006.

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Abstract. Trace elements concentrations were determined in shallow snow samples from 21 sites in the Italian Eastern Alps in order to identify the sources of the contaminants present in the tropospheric winter boundary layer. The collection of superficial snow layers was carried out weekly at altitudes between 1000 and 3000 m next to meteorological stations, far away from villages, roads and ski slopes. Ultra clean procedures were adopted in order to avoid contamination of the snow during the different experimental phases. Trace elements (Ag, Ba, Bi, Cd, Co, Cr, Cu, Fe, Mo, Mn, Pb, Sb, Ti, U, V and Zn) were determined by Inductively Coupled Plasma Sector Field Mass Spectrometer (ICP-SFMS). Ancillary parameters such as major ions (SO42−, NO3−, Ca2+;, Mg2+, K

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Ensign, Kristine A., Brian M. Dodge, Debra Herbenick, and Carrie L. Docherty. "Development of an Instrument to Assess Athletic Trainers' Attitudes Toward Transgender Patients." Journal of Athletic Training 53, no. 4 (April 1, 2018): 431–36. http://dx.doi.org/10.4085/1062-6050-496-16.

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Context: The unique contexts in which athletic trainers (ATs) work require specific tools in order to understand their attitudes toward diverse patient populations, including sexual and gender minorities. Objective: To develop and validate the Attitudes Toward Transgender Patients (ATTP) instrument for ATs. Design: Cross-sectional study. Setting: Semistructured interviews, paper-based questionnaire, and electronic questionnaire. Patients or Other Participants: Six ATs completed semistructured interviews to develop themes regarding transgender patients. Additionally, 39 students in professional and postprofessional athletic training programs answered questionnaires designed to elicit statements regarding transgender patients. For item reduction, a sample of 3000 ATs were e-mailed (response rate = 17%), and for validation, another sample of 3000 ATs were e-mailed (response rate = 13%). Athletic trainers' e-mail addresses were obtained from the National Athletic Trainers' Association. Data Collection and Analysis: The 3 phases were (1) exploratory interviews, (2) construct validity and item reduction, and (3) criterion validity. Items were created based on interviews and questionnaires. Principal axis factoring was used for item reduction, and Pearson correlations were used for validation. Results: Thirty-six statements pertaining to transgender patients were developed from the interview and questionnaire data. After item reduction, 10 items remained to form the ATTP (α = .834). For validation, the ATTP and Transphobia Scale were significantly correlated (r = .723; P < .001). Conclusions: The ability to assess attitudes toward transgender patients will allow clinicians to identify needed areas of focus for training and education. The ATTP assesses affective and cognitive attitudes and behavioral intentions toward transgender patients in common clinical settings.

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Kaufmann, Kai B., Wolfgang Baar, Kai Silbach, Julian Knörlein, Bernd Jänigen, Johannes Kalbhenn, Sebastian Heinrich, Przemyslaw Pisarski, Hartmut Buerkle, and Ulrich Göbel. "Modifiable Risk Factors for Delayed Graft Function After Deceased Donor Kidney Transplantation." Progress in Transplantation 29, no. 3 (June 5, 2019): 269–74. http://dx.doi.org/10.1177/1526924819855357.

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Purpose: Delayed graft function is a major complication after kidney transplantation affecting patients’ long-term outcome. The aim of this study was to identify modifiable risk factors for delayed graft function after deceased donor kidney transplantation. Methods: This is a single-center retrospective cohort study of a university transplantation center. Univariate and multivariate step-wise logistic regression analysis of patient-specific and procedural risk factors were conducted. Results: We analyzed 380 deceased donor kidney transplantation patients between October 30, 2008 and December 30, 2017. The incidence of delayed graft function was 15% (58/380). Among the patient-specific risk factors recipient diabetes (2.8 [1.4-5.9] odds ratio [OR] [95% confidence interval [CI]]), American Society of Anesthesiologist score of 4 (2.7 [1.2-6.5] OR [95% CI]), cold ischemic time >13 hours (2.8 [1.5-5.3] OR [95% CI]) and donor age >55 years (1.9 [1.01-3.6] OR [95% CI]) revealed significance. The significant intraoperative, procedural risk factors included the use of colloids (3.9 [1.4-11.3] OR [95% CI]), albumin (3.0 [1.2-7.5] OR [95% CI]), crystalloids >3000 mL (3.1 [1.2-7.5] OR [95% CI]) and mean arterial pressure <80 mm Hg at the time of reperfusion (2.4 [1.2-4.8] OR [95% CI]). Conclusion: Patients undergoing deceased donor kidney transplantation with a mean arterial pressure >80 mm Hg at the time of transplant reperfusion without requiring excessive fluid therapy in terms of colloids, albumin or crystalloids >3000 mL are less likely to develop delayed graft function.

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Volkov, V. V., and Y. Zhu. "In-Situ Tem Dynamic Magnetizing Experiments Used To Identify The Pinning Centers In Hard Magnets Re13.75fe80.25b6 (Re=Nd, Pr)." Microscopy and Microanalysis 5, S2 (August 1999): 20–21. http://dx.doi.org/10.1017/s1431927600013428.

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The new JEOL 3000F high resolution electron microscope at BNL has been optimized for Lorentz imaging. The necessary field-free environment around the sample is obtained by switching off the objective lens in the free-lens control mode, and the associated reduction in magnification is compensated for by a Gatan post-column image filter (GIF) at ∼ 20x magnification. Fresnel imaging is obtained by defocusing with objective mini-lens (OM). The use of low angle diffraction with an aperture located at the back focal plane makes it possible to obtain Foucault images.In-situTEM dynamic magnetizing experiments combined with Lorentz magnetrc microscopy both in Fresnel and Foucault modes were used to characterize the magnetic structure of some hard and relatively soft magnets, Nd13.75Fe80.25B6 and Pr13.75Fe80.25B6, prepared by different processing routes. The goal of these in-situexperiments was to develop a reliable and effective procedure to search for, identify, and classify the different pinning centers present in real magnets that accord with their “pinning power” versus applied magnetic field.

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Journal articles on the topic 'Identafi 3000'

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