Dissertations / Theses on the topic 'Identification hybride'
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Maire, Sarah. "Cohabitation de logiques institutionnelles au sein d’une organisation hybride : une approche par les représentations textuelles et visuelles." Thesis, Université de Lorraine, 2018. http://www.theses.fr/2018LORR0135.
Full textThe purpose of this thesis is to bring new insights on the identification and cohabitation of institutional logics in a hybrid organization. The question of the identification of logics is the main concern to then be able to understand the inner workings of logics, their relationships and implications in hybrid organisations, under the influence from a plurality of logics. By taking into account both textual and visual data, we contribute to consider the information contained in these data, as their role in the diffusion of logics. To support the cohabitation of logics, hybrid organizations use texts and visuals in different support. Focused on a case study, the organisation of Scouts and Guides of France, we develop several content analyses, qualitative and quantitative, textual and visual, to capture logics and understand their relationships
Khatami, Iman. "Free-field inlet / outlet noise identification on aircraft engines using microphones array." Thèse, Université de Sherbrooke, 2014. http://hdl.handle.net/11143/7581.
Full textRésumé : La présente thèse étudie la discrimination du bruit d'entrée / de sortie des moteurs d'avion dans des tests statiques en champ libre en utilisant des antennes de microphones en champ lointain. Diverses techniques sont comparées pour ce problème, dont la formation de voie classique (CB), la méthode inverse régularisée (régularisation de Tikhonov), la formation de voies généralisée inverse (L1-GIB), Clean-PSF, Clean-SC et deux méthodes proposées qui s'appellent la méthode hybride et la méthode Clean-hybride. La méthode la formation de voie classique est désavantagée en raison de son besoin de nombreux microphones de mesure. De même, la méthode inverse est désavantagée en raison du besoin d'information a priori sur les sources. La régularisation Tikhonov classique fournit des améliorations dans. la stabilité de la solution; cependant elle reste désavantageuse en raison de son exigence d'imposer une pénalité plus forte pour des positions de source non détectées. Des sources cohérentes et incohérentes peuvent être résolues par la formation de voies généralisée inverse (L1-GIB). Cet algorithme peut identifier les sources multi- polaires aussi bien que les sources monopolaires. Cependant, l'identification de source par la formation de voies généralisée inverse prend beaucoup de temps et exige un ordinateur avec une capacité de mémoire élevée. La méthode hybride est une nouvelle méthode de régularisation qui implique l'utilisation d'un traitement par formation de voie a priori pour définir une norme discrète et dépendante des données pour la régularisation du problème inverse. En comparaison avec la formation de voie classique et la méthode inverse, l'approche hybride (régularisation par formation de voie) fournit des cartographies améliorées d'amplitudes de sources sans aucune complexité supplémentaire substantielle. Bien que la méthode hybride lève les limitations des méthodes classiques, l'application de cette méthode pour l'identification de sources de faible puissance en présence de sources de forte puissance n'est pas satisfaisante. On peut expliquer ceci par la plus grande pénalisation appliquée à la source plus faible dans la méthode hybride, qui aboutit à la sous-estimation de l'amplitude de cette source. Pour surmonter ce défaut, la méthode Clean-SC et la méthode Clean-hybrides proposée qui est une combinaison de la méthode hybride et de Clean-SC sont appliquées. Ces méthodes éliminent l'effet des sources fortes dans les cartographies de puissance de sources pour identifier les sources plus faibles. Les méthodes proposées qui représentent la contribution principale de cette thèse conduisent à des résultats fiables et ouvrent des nouvelles voies de recherche. L'étude théorique de toutes les approches est menée pour divers types de sources et de configurations microphoniques. Pour valider l'étude théorique, plusieurs expériences en laboratoire sont réalisées à Université de Sherbrooke. Les méthodes proposées ont été appliquées aux données de bruit mesurées d'une turbo-soufflante Pratt & Whitney Canada pour fournir une meilleure résolution spatiale des sources acoustique et une solution robuste avec un nombre limité des microphones de mesure comparé aux méthodes existantes.
Mahaman, Bachir Dodo Sahia. "Identification de nouvelles protéines des synapses à ruban." Thesis, Montpellier 1, 2014. http://www.theses.fr/2014MON1T018.
Full textInner hair cells (IHCs) are the sensory cells of the cochlea, the organ of hearing. IHCs transduce sound stimulation into the release of glutamate onto the afferent auditory nerve fibers. To achieve this task, IHCs harbor at their presynaptic side a large organelle, the so-called synaptic ribbon, surrounded by a monolayer of glutamate-filled synaptic vesicles. Exocytosis of glutamate at the hair cell ribbon synapse seems to be unconventional as the synaptic machinery, depicted so far, differs from most of the nervous system synapses. The goal of this work was to identify new members of the synaptic machinery of the hair cell ribbon synapse. To do so, we took advantage of the yeast two-hybrid system using a cochlea cDNA library as the prey and Ribeye (the major ribbon component) as the bait. Transcription factors were highly represented in our screening assay, most probably because Ribeye is highly homologous to the transcription factor Ctbp2. They probably interact with Ctbp2 in the nucleus. Our results underlined the difficulty to identify protein interactions because of the nature of Ribeye itself. However, we found ubiquitin system components among the other candidates, suggesting an ubiquitin-dependent regulation of the activity and/or structure of synaptic ribbons
Cougot, Nicolas. "Identification et caractérisation des facteurs impliqués dans la dégradation des ARNm eucaryotes." Paris 11, 2004. http://www.theses.fr/2004PA112230.
Full textIn eukaryotic cells, gene expression involve three main steps. First DNA is transcribed in RNA. This RNA, after maturation is exported to the cytoplasm where it will be translated into protein. MRNA decay has been shown to be a key step in gene expression regulation. Our study was on mRNA decapping, a step involved in two decay pathways. We show that in human cells, hDcp1 and hDcp2, form the decapping complex, and co-localize in cytoplasmic foci. Other studies show that other factors, involved in mRNA decay are also located in these cytoplasmic foci. We show that these foci are not related to already described stress granules. By using RNA interference, we show that these structures are active mRNA decay centers. All the factors involved in mRNA decapping form a network of interactions ensuring the transition between translation and degradation. Our second project was to map the domains of interaction between these different factors. Using the two-hybrid method, we initiate the mapping of the different domains involved in these interactions. These studies would allow better comprehension of the formation of the decay center in human cells by using the results obtained with S. Cerevisiae as a starting point
RAMDANI, LOUNI RABEA. "Detection de ruptures de modeles et identification parametrique hybride de systemes non stationnaires." Paris 6, 1993. http://www.theses.fr/1993PA066460.
Full textBarzaj, Yasmin. "Conception d'une architecture hybride pour l'instrumentation et l'étude du comportement des 2RM." Thesis, Université Paris-Saclay (ComUE), 2016. http://www.theses.fr/2016SACLS119.
Full textIn this thesis, we propose a new technic to identify a hybrid system for Data Acquisition,by using ad-hoc sensors on the vehicle, the sensors in the recent smartphones, MBED and CAN-BUS. The assumption is that the Smartphone's sensors will reduce the complexity and the high cost of these instrumentations. The objective is obtaining acceptable measurement accuracy of the collected trajectories and enable for a large-scale deployment of the system's instrumentation, such as a helpful system in the domain of transport. Weshow in this thesis how to build a hybrid system by depending on the properties of the used sensors in both the smartphones and in the vehicles to identify several situation like a failure sensor, accident situation and Rider's behaviour. This system is tested and evaluated on several real time on line - off- line including the used mode and method
Marret, Séverin. "Identification de cibles sur critères cinématiques." Bordeaux 1, 2008. http://www.theses.fr/2008BOR13613.
Full textAzzouzi, Naoual. "Analyse comparative des génomes d’espèces majeures pour l’aquaculture par cartographie RH et Identification des répertoires des récepteurs olfactifs (OR) et TAAR des cichlides." Thesis, Rennes 1, 2013. http://www.theses.fr/2013REN1S152/document.
Full textThe construction of genome maps consists in placing tags, called markers, on the chromosomes. The denser in evenly spaced markers is a map, the more it is informative, leading to the development of more future applications. Among the different mapping strategies, those using radiation hybrids (RH) have numerous advantages. Indeed, polymorphic markers such as microsatellites, useful for linkage analyses, as well as gene markers, polymorphic or not and allowing comparative mapping with other genomes and definition of synteny breaks and conservation, can be localized on a RH map. Not only these maps are useful to identify genes of interest but they are also essential tools to study genome evolution. Among numerous vertebrates of interest, we constructed RH maps of fishes and cichlids in particular. Indeed these fishes constitute interesting genetic models from economical and evolution points of view. Having genome maps of several of these fishes would help to identify genes implicated in phenotypical or pathological traits, or even markers linked to stress and reproduction. My thesis work consisted in the construction of a genome map of the sea bass, a tilapia RH panel and its RH map, a sturgeon RH panel as well as an oyster RH panel. The tilapia map was used for the assembly of the sequencing data of the tilapia genome. Thanks to this last work realized with an international consortium we had a privileged access to the sequencing data of five cichlid genomes (O. niloticus, P. nyererei, H. burtoni, N. brichardi and M. zebra). We then participated to the annotation of these genomic sequences. In particular we have identified and characterized the olfactory receptor gene (OR) repertoires and of the trace amine-associated receptor (TAAR) gene repertoires of these five cichlids. Which are then made of 158, 88, 90, 69, 102 OR genes and 45, 19, 23, 12, 20 TAAR genes respectively
Meslem, Nacim. "Atteignabilité hybride des systèmes dynamiques continus par analyse par intervalles : application à l'estimation ensembliste." Phd thesis, Université Paris-Est, 2008. http://tel.archives-ouvertes.fr/tel-00461673.
Full textBergeault, Karine. "Identification de deux gènes NPR1chez les VITACEAE, analyse de leur diversité de séquences et interactions avec les facteurs de transcription VvTGA." Phd thesis, Université de Haute Alsace - Mulhouse, 2010. http://tel.archives-ouvertes.fr/tel-00769928.
Full textNouailletas, Rémy. "Modélisation hybride, identification, commande et estimation d'états de système soumis à des frottements secs : application à un embrayage robotisé." Grenoble INPG, 2009. http://www.theses.fr/2009INPG0107.
Full textThis work deals with the modelling, the identification and the control of systems submitted to dry friction. The thesis is divided into four parts. The first one develops two items: the modelling of complex mechanical system and the state of art of existing models for dry friction. The second part concerns the hybrid modelling of system submitted to dry frition. Based on a new generic model, three models are proposed with increasing complexity. The third part is devoted to the practical identification of dry friction. Methods robust to the quantification noise on the data are presented. The last part is about control: firstly, an original approach of non-linear control is proposed. Then, the parameters uncertainties are accounted into the model bya LPV approach. Thus, a robust controller is obtained. All the presented works are validated on a real test bench of a clutch-by-wire
Holbert, Sébastien. "Contribution à l'étude du rôle des partenaires moléculaires de la huntingtine dans la physiopathologie de la maladie de Huntington : identification et caractérisation des protéines CA150 et CIP4." Paris 6, 2003. http://www.theses.fr/2003PA066159.
Full textHariri, Essamlali Kaoutar El. "Modélisation hybride du canal de propagation dans un contexte industriel." Thesis, Poitiers, 2014. http://www.theses.fr/2014POIT2336/document.
Full textThis thesis focuses on the modeling of the propagation channel in industrial environments. In this context, the propagation channel has a different behavior than typically encountered in indoor. This is due to the construction of buildings that are larger and open and the presence of machines, moving objects and metal materials encountered in these environments. Thus, the existing indoor channel models are not valid. Using deterministic models as an alternative is possible, but limited by the computing time.To address this problem, we propose a hybrid channel model for communications in industrial environments inspired by a ray tracing method and Winner model. The originality of this model is its hybrid nature consisting, in preprocessing, in partitionning the environment in areas of visibility or non-visibility «weak» and «strong» based on deterministic criteria related to the wave propagation. A statistical model, as WINNER , using the concept of cluster is then played in each of these areas and faithfully reproducing the evolution of the characteristic parameters of the identified clusters. We have validated our model by comparing it firstly to a deterministic model and then to measurement. Its robustness as well that of WINNER are tested by simulating them in three different environments and by comparing them with the deterministic model
Le, Halpere Gilles. "Étude d'une machine à absorption fonctionnant en mode climatisation : identification d'un nouveau mélange adapté à un cycle hybride original à hautes performances." Toulouse, INPT, 1998. http://www.theses.fr/1998INPT101G.
Full textDang, Weidong. "Finite element modelling of hybrid (spot welded/bonded) joints under service conditions." Thesis, Compiègne, 2015. http://www.theses.fr/2015COMP2187/document.
Full textSpot welding and adhesive bonding are widely used in joining of sheet metals, such as assembling of car body-in-white. Recently, spot weld and adhesive are combined to make weld bonded joint, which is employed to join Advanced High Strength Steel to improve the stiffness and crashworthiness of car body. In industry, the assessment of designing prior to prototype requires reliable constitutive models in terms of the prediction of the mechanical behaviors. The FE model of weld bonded joint is a new challenge as it should combine the models of spot welding and the models of adhesive. This thesis focuses on the modeling of weld bonded joint by DP600 steel and structural adhesive SikaPower®-498. The model of weld bonded joint consists of solid model and simplified model. The former is devoted to predict the behavior of weld bonded joint on small-scale specimen: KS2 and lap-shear. The latter can be used to predict the performance of large components with acceptable computational cost. As regards solid model, spot welded joint and adhesive bonded joint behaviors are separately identified by KS2 specimen under different loading path. The inhomogeneities in fusion zone and heat affected zone of spot weld are taken into account via the scaling of the flow stress of base metal. The scaling factors are calibrated by inverse identification. Gurson model is used to predict ductile fracture in heat affected zone and base metal while cohesive zone model is employed to simulate quasi-brittle fracture in the interface of fusion zone. The parameters of cohesive zone model are identified by the J-integral at the notch tip of spot weld crack. Cohesive zone elements with traction-separation-laws are also used to predict adhesive debonding. Model parameters are calibrated by Double Cantilevered Beam and End Notched Flexure specimens, corresponding to Mode-I and Mode-II fracture respectively. The model developed for spot weld is associated with adhesive model to predict weld bonded joint. As regards simplified model, connector elements are employed to predict the damage of spot weld. The parameters of connector element are identified by KS2 tests under different loading paths. Finally, the simplified model of spot welding, adhesive bonding, and weld-bonding are validated by T-joint which can represent the B-pillar of car body
Özkizilkaya, Özlem. "Thermosensibilité de la demande électrique : identification de la part non linéaire par couplage d'une modélisation bottom-up et de l'approche bayésienne." Thesis, Paris, ENMP, 2014. http://www.theses.fr/2014ENMP0050/document.
Full textThe growing heat pump market contributes to the increase in temperature sensitivity of electricity demand. It becomes necessary to understand the impact of temperature sensitive end-uses of electricity, including those which are correlated non-linearly to the outside temperature. In this context, this thesis aims to build a modeling framework to i) analyze the influencing factors of the temperature sensitivity of electricity demand from a physical description of temperature-sensitive equipment, and ii) to perform diagnoses of these parameters of influence by taking into account the associated uncertainties. A hybrid modeling approach that benefits the advantages of statistical models and physical models is used to answer these questions.Firstly, the temperature-sensitive part of electricity demand is estimated by a predictive top-down model. Then a physical model to analyze the temperature sensitivity at regional level is developed based on building thermal energy needs. A regional coefficient of performance (COP) is determined for the whole installed heat pumps by using pseudo-physical models which are regressed on manufacturer data or actual performance measures. Finally, the parameters of influence of the developed temperature sensitivity model are estimated using the Bayesian approach which provides a framework for the treatment of uncertainty in the form of probabilities. Equivalent coefficients of heat loss, an equivalent internal temperature, as well as the share of Joule heating and the share of heat pumps for the regional building stock are obtained
Kerbouai, Hamza. "Modélisation, dimensionnement et optimisation d'un capteur hybride pour la détection des deux roues motorisées dans le trafic routier." Thesis, Belfort-Montbéliard, 2015. http://www.theses.fr/2015BELF0260/document.
Full textFor several years the road safety numbers show the need to develop a technological tool that aims to know thepowered two wheelers vehicles behavior (2PW) to improve their security. From this problematic arise our researchworks that come under the project METRAMOTO (Powered two wheelers traffic measurement for road safety andrisks assessment). The main objective is modeling, sizing and optimization of an hybrid sensor consisted ofelectromagnetic loops and piezoelectric shock sensors. The idea is to use electromagnetic loops to discriminate the2PW presence from the other vehicles, combined with piezoelectric segments to detect the shocks produced by thevehicles wheels passage, all associated with a management algorithm and data processing. Today the sizing of thedetection systems based on electromagnetic loops or piezoelectric cables is done experimentally on controlled sitesusing several vehicles types. This technique requires significant test series which are costly and dangerous. Thisstudy aims to modeling the different interactions between the studied sensor and vehicles in order to its sizing.Electromagnetic and electromechanical models are developed to describe the different interactions that take placebetween electromagnetic loops on the one hand, between electromagnetic loops and vehicles on the other handand those between vehicle wheels and piezoelectric cable. On the basis of established models, a general approachis elaborated driving to sizing the hybrid sensor for any given road. We are also interested to the data processingcoming from the hybrid sensor for which we propose an approach to identifying the different vehicle categoriesincluding the 2PW. Two sensor configurations for two different roads are then proposed. They are associated atdata processing algorithms allowing the acquisition of loops and cables signals, the distinction between the differentvehicles classes, the estimation of the vehicles positions on the road and the measuring of their speed
Cousturier, Richard. "Amélioration par la gestion de redondance du comportement des robots à structure hybride sous sollicitations d’usinage." Thesis, Université Clermont Auvergne (2017-2020), 2017. http://www.theses.fr/2017CLFAC090/document.
Full textIndustrial robots have evolved fundamentally in recent years to reach the industrial requirements. We now find more suitable anthropomorphic robots leading to the realization of more complex tasks like deformable objects cutting such as meat cutting or constrained to high loading like during machining. The behavior study of anthropomorphic robots, parallel or hybrid one highlights a kinematic and dynamic anisotropy, which impacts the expected accuracy.This thesis studied the integration of the kinematic redundancy that can partially overcome this problem by well setting the task to achieve it in a space compatible with the expected capacity.This work helped us to improve our optimization tool and to try it on both FE model of the robot and real robot.Thus, the thesis makes contributions to: - the definition of criteria adapted to the realization of complex and under high loading task for the management of the kinematic redundancy; - the structural behavior identification, under loading, by metrology tools (Laser tracker) ; - the behavior optimization to improve the cutting process quality during machining ; - robots finite elements modeling using stiffness identification for both bodies and joints
Randoux, Béatrice. "Modifications dans l'expression des gènes au cours de l'embryogenèse somatique chez un hybride de chicorée : identification de gènes codant pour une protéine de liaison au GTP." Lille 1, 1999. https://pepite-depot.univ-lille.fr/LIBRE/Th_Num/1999/50376-1999-339.pdf.
Full textParis, Manuel. "Identification du comportement en torsion à fort facteur d’avancement des pales d’hélicoptère conventionne : application à la réduction des efforts de commandes sur une formule hybride haute vitesse de type X3." Thesis, Paris, ENSAM, 2014. http://www.theses.fr/2014ENAM0045.
Full textNowadays, the increase of cruise speed for conventional helicopters (main rotor and anti-torque rear rotor) reaches an asymptote. The X3 concept proposed by Airbus Helicopters is a hybrid helicopter combining 2 propellers at the tip of small wings in order to unload the main rotor. This solution is economically viable because it reuses well-proven technologies such as the Spheriflex rotor, already used on the Dolphin family for many years. X3 flight tests have shown a good behavior of the rotor concerning performances as well as handling qualities, but control loads in the rotor system were significantly higher in cruise conditions than for conventional helicopters. In order to save the payload, over-sizing of the mechanical parts in order to withstand these loads can't be an appropriate solution. The work presented in this thesis deals with the problematic of control loads reduction.In order to reduce the control loads, the first step is to highlight the roots of these loads and to get a predictive tool over the whole flight domain. Experimental measurements from X3 flight tests give the aerodynamic loads on the blade sections, leading to understand the blades torsional dynamic behavior in several flight test cases (cruise, turns and high speed flight). Phenomena responsible for the increase of control loads are then identified, and the rotor computation tool HOST used at Airbus Helicopters is corrected to predict accurately control loads over the conventional as well as the high speed helicopter flight domain.The corrected rotor computation tool HOST, associated with the physical comprehension of the blade torsional dynamics, is used to quantify the possible solutions proposed for control loads reduction. Two main ways are studied: the optimization of the control system architecture and the reduction of pitch link loads. The optimization of control system architecture shows a dramatic reduction of control loads in the servo actuators and in the non-rotating scissors, thanks to an optimization algorithm developed during this thesis. The reduction of pitch link loads study shows that the optimization of the helicopter equilibrium leads to drastic reduction, whereas the modification of blade design does not show any significant reduction even at high speed
Azzouzi, Naoual. "Analyse comparative des génomes d'espèces majeures pour l'aquaculture par cartographie RH et Identification des répertoires des récepteurs olfactifs (OR) et TAAR des cichlides." Phd thesis, Université Rennes 1, 2013. http://tel.archives-ouvertes.fr/tel-00989008.
Full textAtlati, Samir. "Développement d'une nouvelle approche hybride pour la modélisation des échanges thermiques à l'interface outil-copeau : application à l'usinage de l'alliage d'aluminium aéronautique AA2024-T351." Thesis, Université de Lorraine, 2012. http://www.theses.fr/2012LORR0200/document.
Full textThis PhD. thesis is realised in the framework of an international cooperation between the University of Lorraine (France) and the University of Oujda (Morocco). The work done concerns the modelling of machining process by material removal. Two important aspects of machining have been investigated: the chip formation process and the heat exchange at the tool-chip interface. In the first part of the thesis, a FE modelling of the cutting process has been established. Chips segmentation have been particularly analysed using à new parameter (Segmentation Intensity Ratio) allowing the quantification of the phenomenon. A correlation has been established between the cutting force reduction and the chip segmentation intensity. The second part of the thesis has been devoted to the study of heat exchange at the tool-chip interface, among other phenomena that contribute to the tool wear. One important point of the study is the establishment of a hybrid identification procedure (analytical/numerical) to estimate the heat flux transmitted into the cutting tool, and identification of the heat partition coefficient at the contact interface for each cutting speed. With identified values of the heat partition coefficient obtained by varying the cutting speed, a heat exchange multi-branch law has been proposed and parameters of this law have been identified. This law corresponds firstly to the evolution of the heat partition coefficient as a function of the cutting speed. Thereafter, it was defined in term of the relative sliding velocity at the tool-chip contact interface, in order to implement it in a FE code. The user interface VUINTER of Abaqus/Explicit has been used to implement the proposed law, to fully control the mechanical and thermal contact. It is henceforth possible to implement with this user interface any thermomechanical contact (friction, heat partition coefficient, etc.). The implementation via the user subroutine VUINTER was validated first on adequate tests, then on machining. The obtained results for heat fluxes with this new procedure are in good agreement with experimental measurements for the tool-workmaterial couple considered: AA2024-T351/WC-Co
Van, Wayenbergh Réginald. "Recherche de partenaires protéiques du facteur de transcription HRT1 par la technique du double hybride: identification de BOIP, nouvel ADNc codant une protéine interagissant avec le domaine Orange de HRT1." Doctoral thesis, Universite Libre de Bruxelles, 2004. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/211120.
Full textTout d’abord nous avons construit les outils appropriés pour l’élaboration du travail, à savoir, les clones de levures exprimant les appâts spécifiques des domaines de la protéine étudiée et la création d’une banque d’ADNc du xénope au stade de la neurulation. Ensuite, trois criblages ont été réalisés. Dans le premier cas, nous avons recherché les partenaires des domaines bHLH et Orange (bHLH-O). Le domaine bHLH est en effet responsable de la dimérisation de ce type de protéine. Le domaine Orange qui suit le domaine bHLH, pourrait participer dans le choix du partenaire d’hétérodimérisation. Nous avons isolé deux facteurs de type bHLH-Orange apparentés à HRT1, XHairy1 et XHairy2b et confirmé leur interaction avec XHRT1. Les domaines impliqués dans ces interactions sont les bHLH-O pour les trois facteurs. Ce même criblage nous a permis d’isoler un nouvel ADNc qui code une protéine sans domaine apparent connu actuellement. Nous avons montré que cette protéine reconnaissait spécifiquement le domaine Orange de HRT1 mais pas celui des autres facteurs de type bHLH-O. Elle a été baptisée BOIP pour Bc8 Orange Interacting Protein. Le rôle physiologique de cette interaction n’a pu être démontré. Nous avons établi que la protéine BOIP pouvait aussi s’homodimériser. Nous avons aussi déterminé son profil d’expression chez le xénope et la souris. Son transcrit est hautement présent dans les testicules adultes. La protéine pourrait donc jouer un rôle important dans la spermatogenèse. Les deux autres criblages, utilisant les domaines situés dans la partie C-terminale de XHRT1, ont apporté des nouveaux partenaires potentiels, mais ces interactions n’ont pu être confirmées dans un système indépendant.
Enfin, en étudiant plus en détail les interactions entre XHRT1 et XHairy1 ou XHairy2b, nous avons mis à jour une possible fonction de spécificité dans le choix du partenaire dans la région C-terminale de HRT1. La formation de ces dimères pourrait jouer un rôle dans la formation du tube neural mais également dans d’autres différenciations tissulaires.
Doctorat en sciences, Spécialisation biologie moléculaire
info:eu-repo/semantics/nonPublished
Domlan, Elom Ayih. "Diagnostic des systèmes à changement de régime de fonctionnement." Phd thesis, Institut National Polytechnique de Lorraine - INPL, 2006. http://tel.archives-ouvertes.fr/tel-00107611.
Full textMagnard, Clémence. "Approche fonctionnelle de la protéine codée par le gène de prédisposition au cancer du sein BRCA1 : identification de partenaires protéiques de sa région carboxy-terminale BRCT." Lyon 1, 2002. http://www.theses.fr/2002LYO1T049.
Full textGinis, Olivia. "Identification de facteurs de transcription régulateurs de la voie de biosynthèse des alcaloïdes indoliques monoterpéniques chez Catharanthus roseus." Thesis, Tours, 2012. http://www.theses.fr/2012TOUR4014/document.
Full textCatharanthus roseus is a tropical plant producing specifically monoterpene indole alkaloids (MIA) of high interest due to their therapeutical values. In C. roseus cells, the terpenoid branch including the methyl erythritol phosphate pathway (MEP) provides the MIA terpenoid moiety and is regarded as limited for MIA biosynthesis. This branch presents a coordinated transcriptional regulation in response to hormonal signals leading to MIA production. In this context, bioinformatic analysises and functional characterization of MEP pathway gene promoters allowed the identification of new transcription factor families involved in the MIA pathway regulation. Members of ZCT proteins, WRKY and type B RR families specifically interact with the hds promoter from the MEP pathway and regulate its activity. This work permits to gain into insight the transcriptional network controlling the MIA biosynthesis. It is possible now to consider using transcription factor that act as activators and target genes from the terpenoid branch to increase the accumulation of alkaloids of pharmaceutical interest in C. roseus by metabolic engineering approaches
Malbert-Colas, Laurence. "Recherche et identification de partenaires du canal épithélial à sodium ENaC : étude du rôle potentiel de ces partenaires dans la régulation de l'activité de ENaC." Paris 7, 2003. http://www.theses.fr/2003PA077168.
Full textWebb, Daniel Martin. "Hybrid dynamic modeling and identification." Connect to online resource, 2007. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3273671.
Full textRadanielson, Mariot Ando. "Identification de nouveaux traits de sélection pour améliorer la productivité en situation de déficit hydrique chez le tournesol." Thesis, Montpellier, SupAgro, 2011. http://www.theses.fr/2011NSAM0013/document.
Full textThis work was an attempt to assist sunflower breeding program by crop physiology knowledge to sustain and to improve productivity under water deficit. The approach was based on using SUNFLO-CLIMATOR, a biophysical crop modelling to identify the limiting factors to plant productivity. These factors were considered as potential new traits for breeding program. Their assessment for this objective corresponded to four criteria: genotypic variability, impact on plant productivity, heritability and simplified phenotyping method. Thus, traits related to genotypic parameters of three processes were analysed: phenology, architecture and soil water uptake. Their variability was evaluated on field and greenhouse experiments carried out with 19 inbred lines and 125 hybrids. Sensitivity analysis of plant yield, simulated with SUNFLO-CLIMATOR model, was then done to estimate the impact of the parameter variability among the studied genotypes. Quantitative genetic analyses were used to evaluate their heritability and the combining ability of the parental inbred lines.Large phenotypic variability was observed for each parameter with a significant “genotype” effect. Thermal time for flowering displayed high heritability about H² = 0.78. Thermal time to physiological maturity (M3) displayed high environmental effect on its variability. Its genotypic variability would probably need new way of modelling such as the development of a seed growth module. Architectural traits related to canopy size and shape presented also lower heritability (0.20 ≤ H² ≤ 0.39) and their impact on plant productivity depends on their interaction. However the trait position of the largest leaf A2gen and its leaf area A3gen could be yet used to screen the best inbred lines for improving radiation interception efficiency of the hybrids during the grain-filling phase.Root depth is a relevant trait for deeper soil. Its access remains difficult and time consuming. For shallower or medium depth soil, higher water extraction capacity seemed allow higher plant yield with linear relationship about 0.8 – 1.5 q ha-1 more per 1% decrease of soil water content minimal for water extraction. The index of water extraction (IEgen) displayed high value of heritability (0.77 ≤ H² ≤ 0.83). The genotypic parameters A2gen, A3gen, IEgen were confirmed with genetic resources to enhance plant productivity under water deficit. Research for their molecular marker would be a next step for this work and an issue for a new selection assisted by marker molecular and plant modelling
Garletti, Agnès. "Instrumentation du tuteur distant, par l'intermédiaire d'une typologie théorique des habiletés cognitives, afin d'identifier les stratégies cognitives de l'apprenant singulier d'un niveau A2 de français langue étrangère en compréhension écrite au sein d'un dispositif hybride de formation." Phd thesis, Université du Maine, 2013. http://tel.archives-ouvertes.fr/tel-00954893.
Full textGarletti, Agnès. "Instrumentation du tuteur distant, par l’intermédiaire d’une typologie théorique des habiletés cognitives, afin d’identifier les stratégies cognitives de l’apprenant singulier d’un niveau A2 de français langue étrangère en compréhension écrite au sein d’un dispositif hybride de formation." Thesis, Le Mans, 2013. http://www.theses.fr/2013LEMA3007/document.
Full textA Given that in his perception activities in university Online teaching and learning environments, the tutor has difficulty in detecting cognitive strategies that cause a blockage and which requires specific instrumentation for visualize the cognitive activity of the learner in his mediated learning path, our research objective is to instrument an On-line tutor for this actor with hybrid training on the UMTICE platform that can identify the cognitive strategies in the individual French as Foreign Language learner’s written comprehension. This research problem gives rise to two research hypotheses, first for the design of a theoretical typology of cognitive abilities in order to name the cognitive strategies that this learner could use when performing written comprehension tasks, and second to qualify the use of our tool by the On-line tutor in his perceptual cognitive identification function during the experiment that took place in a particular course at the CIEF of University Lumière Lyon 2
Gapaillard, Muriel. "Représentation, commande et identification de systèmes hybrides." Angers, 2005. http://www.theses.fr/2005ANGE0023.
Full textTwo classes of hybrid systems with controlled or autonomous jumps and switchings are studied. Continuous representations of these systems are introduced, which enable to avoid difficulties associated with discontinuities. These representations are used to solve optimal control and identification problems. This approach, leading to the replacement of a hybrid problem by a continuous one, is justified by convergence theorems to either classical minima or epsilon-quasiminima with no compacity assumption, that are demonstrated by Gronwall’s lemma and Lebesgue’s theorem. These representations enable to solve hybrid problems by means of methods adapted to continuous problems. This possibility is illustrated by the use of calculus of variations. The practical advantages brought by the representations are highlighted
Ferro, Humberto Fioravante. "Hybrid convex combinations for IIR system identification." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/3/3142/tde-04072016-103658/.
Full textA baixa complexidade dos filtros adaptativos (FAs) IIR é atrativa para aplicações em tempo real, mas certos inconvenientes têm impedido sua ampla utilização até agora. Para os FAs baseados no gradiente descendente, condições operacionais adversas suscitam problemas de convergência em cenários de identificação de sistemas: pólos subamortecidos ou agrupados, submodelagem ou sinais correlacionados originam superfícies de erro onde a adaptação desacelera em grandes planícies ou para em mínimos locais sub-ótimos que não podem ser identificados como tais a priori. Além disso, a não-estacionaridade do regressor de entrada causada pela recursividade do filtro e as aproximações feitas pelas regras de atualização dos algoritmos de gradiente estocástico restringem o passo de aprendizado a valores pequenos, retardando a convergência. Neste trabalho, propomos estratégias de aprimoramento de desempenho baseadas em combinações híbridas e estáveis de FAs que alcançam taxas de convergências mais altas do que FAs IIR comuns.
Hamidoghli, Yousef. "Production and identification of interspecific potato somatic hybrids." Thesis, University of the West of Scotland, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283091.
Full textBo, Zhang, Ren Yixun, Yang Dongkai, and Zhang Qishan. "FAST ACQUISITION ALGORITHM FOR HYBRID DS/FH RECEIVER." International Foundation for Telemetering, 2007. http://hdl.handle.net/10150/604569.
Full textThis paper introduced a fast scanning and waiting acquisition method for a DS/FH receiver used in the telemetry field. Mathematic model of the hybrid DS/FH system’s acquisition process is given and discussed. The average acquisition time expression using this method and generalized average acquisition time formula is derived also. The validity of the proposed algorithm is verified after simulation. In the circumstances of Additive Gauss White Noise for the channel, simulation result at Ec/N0= -15dB shows that the average acquisition time is decreased almost 4 times than that of waiting and searching method.
Torres, Reynier Hernández. "Vibration-based damage identification using hybrid optimization algorithms." Instituto Nacional de Pesquisas Espaciais (INPE), 2017. http://urlib.net/sid.inpe.br/mtc-m21b/2017/08.18.16.12.
Full textO problema inverso da identificação de danos estruturais é abordado nesta tese. A solução inversa é obtida resolvendo um problema de otimização usando diferentes algoritmos híbridos. O modelo direto estrutural é resolvido pelo Método dos Elementos Finitos. Código FORTRAN desenvolvido pelo grupo de pesquisa do Laboratório Associado de Computação e Matemática Aplicada (LAC) do Instituto Nacional de Pesquisas Espaciais (INPE) foi aplicado em alguns problemas e, para outros experimentos numéricos, o software NASTRAN foi empregado. O histórico de tempo de aceleração, velocidade ou deslocamento pode ser usado como dados experimentais nesta metodologia. A função objetivo é formulada como a soma da diferença quadrática entre o deslocamento medido e os dados calculados pelo modelo direto. Diferentes metaheurísticas híbridas são testadas, usando uma abordagem em duas etapas. A primeira etapa realiza a exploração em todo o espaço de busca, e a segunda etapa realiza a intensificação a partir da melhor solução encontrada pela primeira etapa. Uma abordagem de otimização combina o Algoritmo de Colisão de Múltiplas Partículas (MPCA) com o método de busca direta Hooke-Jeeves (HJ). O MPCA é melhorado usando diferentes mecanismos derivados da Aprendizagem Baseada na Oposição, como são a Amostragem Baseada no Centro, e a Aprendizagem Baseada em Rotação. Outro otimizador aplicado é o novo q-gradiente, que também é hibridado com o método HJ. A metodologia é testada em estruturas com diferentes complexidades. Supõe-se que os danos são invariante no tempo para gerar as medidas experimentais sintéticas. Dados sem ruído e com diferentes níveis de ruído foram considerados em testes usando modelos implementados em FORTRAN. A maioria dos experimentos foi realizada usando um conjunto completo de dados, de todos os nós possíveis, e um dos experimentos foi feito usando um conjunto incompleto de dados, com um baixo nível de ruído. Para os experimentos utilizando o NASTRAN, foram considerados dados sintéticos sem ruído, e foi utilizado o conjunto completo de dados. Em geral, boas estimativas para localização e gravidade do dano foram alcançadas. Alguns falsos positivos apareceram nas estimativas, mas os danos presentes nos sistemas foram bem identificados.
Houda, Taha. "Human Interaction in a large workspace parallel robot platform with a virtual environment." Electronic Thesis or Diss., université Paris-Saclay, 2020. http://www.theses.fr/2020UPASG047.
Full textThe thesis objective relates to the denition, the implementation and the evaluation of a Motion Cueing Algorithm taking into account the perceptual constraints of the vestibular systemin humans and the constraints related to the movement physics of the used simulator. The latter consists of a series-parallel robotic platform with 8 degrees of freedom, entirely designed in the laboratory and intended primarily to assist people with motor disabilities. This sensory restitution requires multidisciplinary research work in robotics and virtual reality. Moreover, a formalization of dynamic modeling, based on the state of the art, was adapted and the dynamic parameters optimized and identied for the 8 degrees of freedom motion platform. Several methods of trajectory generation, exploitation of the platform redundancy, have been studied, implemented,and compared. The most e cient particle swarm optimization (PSO) method was chosen. This algorithm is then used to optimize the parameters of the platform controller in sliding mode. The simulator was used for a virtual reality ski application reproducing the Combloux resort in Haute-Savoie dedicated to disabled people. The simulation results show a very good trajectory tracking behavior and a good reduction in terms of oscillations. This work will be continued through the use of multi-sensory human-assisted virtual reality interfaces
Ajib, Balsam. "Data-driven building thermal modeling using system identification for hybrid systems." Thesis, Ecole nationale supérieure Mines-Télécom Lille Douai, 2018. http://www.theses.fr/2018MTLD0006/document.
Full textThe building sector is a major energy consumer, therefore, a framework of actions has been decided on by countries worldwide to limit its impact. For implementing such actions, the availability of models providing an accurate description of the thermal behavior of buildings is essential. For this purpose, this thesis proposes the application of a new data-driven technique for modeling the thermal behavior of buildings based on a hybrid system approach. Hybrid systems exhibit both continuous and discrete dynamics. This choice is motivated by the fact that a building is a complex system characterized by nonlinear phenomena and the occurrence of different events. We use a PieceWise AutoRegressive eXogeneous inputs (PWARX) model for the identification of hybrid systems. It is a collection of sub-models where each sub-model is an ARX equation representing a certain configuration in the building characterized by its own dynamics. This thesis starts with a state-of-the-art on building thermal modeling. Then, the choice of a hybrid system approach is motivated by a mathematical interpretation based on the equations derived from an RC thermal circuit of a building zone. This is followed by a brief background about hybrid system identification and a detailed description of the PWARX methodology. For the prediction phase, it is shown how to use the Support Vector Machine (SVM) technique to classify new data to the right sub-model. Then, it is shown how to integrate these models in a hybrid control loop to estimate the gain in the energy performance for a building after insulation work. The performance of the proposed technique is validated using data collected from various test cases
Abdulsattar, Fatimah. "Identification by a hybrid 3D/2D gait recognition algorithm." Thesis, University of Southampton, 2016. https://eprints.soton.ac.uk/404663/.
Full textMuhibullah. "Computation experimental DIC hybrid strategy for robust 3D ductile plastic law identification." Phd thesis, INSA de Lyon, 2012. http://tel.archives-ouvertes.fr/tel-00838763.
Full textLauer, Fabien. "Machines à Vecteurs de Support et Identification de Systèmes Hybrides." Phd thesis, Université Henri Poincaré - Nancy I, 2008. http://tel.archives-ouvertes.fr/tel-00332810.
Full textLe, Van Luong. "Identification de systèmes dynamiques hybrides : géométrie, parcimonie et non-linéarités." Phd thesis, Université de Lorraine, 2013. http://tel.archives-ouvertes.fr/tel-00874283.
Full textIbn, Taarit Kaouther. "Contribution à l'identification des systèmes à retards et d'une classe de systèmes hybrides." Phd thesis, Ecole Centrale de Lille, 2010. http://tel.archives-ouvertes.fr/tel-00587336.
Full textRudloff, Laurent. "Etudes expérimentales de paliers aérostatiques hybrides et des paliers aérodynamiques à feuilles." Poitiers, 2011. http://theses.univ-poitiers.fr/22002/2011-Rudloff-Laurent-These.pdf.
Full textThe thesis activities are made on two different test rigs. On the first test rig, the dynamic characteristics of a hybrid aerostatic bearing are experimentally investigated in a rigid rotor configuration. The rotor is driven up to 60 krpm by an impulse turbine and is horizontally mounted on two identical aerostatic bearings fed with are pressures up to 11 bar. Dynamic loads consist either of impacts provided by a hammer or of added unbalance masses. The test rig can measure the bearing feeding pressures and flow, the rotation speed, the impact force, the displacements of the two bearings and the bearing housing accelerations. This experimental information together with the equations of motion of the rotor enables the identification of the dynamic coefficients of the bearings. A validation of these coefficients is providing by the unbalanced response of the rotor. The second part, on the second test rig, presents the results of the experimental analysis of static and dynamic characteristics of a generation 1 foil bearing. The test rig is of floating bearing type, and can reach the speed of 40 krpm. Two different casings are used for start up and for measurement of dynamic coefficients. In its first configuration, the test rig is designed to measure the start up torque. In its second configuration, a different casing is used to measure the impedances of the foil bearing. Stiffness and damping coefficients are identified from the complex impedances and enable the calculation of natural frequencies. The experimental results show that the dynamic characteristics of the tested bearing have a weak dependence on the rotation speed but vary with the excitation frequency
Jing, Yonghua. "Identification of the Na,K-ATP interacting proteins." University of Toledo Health Science Campus / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=mco1139260222.
Full textMaÏga, Moussa. "Surveillance préventive des systèmes hybrides à incertitudes bornées." Thesis, Orléans, 2015. http://www.theses.fr/2015ORLE2010/document.
Full textThis thesis is dedicated to the development of generic algorithms for the set-membership observation of the continuous state and the discrete mode of hybrid dynamical systems in order to achieve fault detection. This thesis is organized into two parts. In the first part, we have proposed a fast and effective method for the set-membership guard crossing. It consists in carrying out bisection in the time direction only and then makes several contractors working simultaneously to reduce the domain of state vectors located on the guard during the study time slot. Then, we proposed a method for merging trajectories based on zonotopic enclosures. These methods, used together, allowed us to characterize in a guaranteed way the set of all hybrid state trajectories generated by an uncertain hybrid dynamical system on a finite time horizon. The second part focuses on set-membership methods for the parameters or the hybrid state (mode and continuous state) of a hybrid dynamical system in a bounded error framework. We started first by describing fault detection methods for hybrid systems using the parametric approach and the hybrid observer approach. Then, we have described two methods for performing fault detection tasks. We have proposed a method for computing in a guaranteed way all the parameters consistent with the hybrid dynamical model, the actual data and the prior error bound, by using our nonlinear hybrid reachability method and an algorithm for partition which we denote SIVIA-H. Then, for hybrid state estimation, we have proposed a method based on a predictor-corrector, which is also built on top of our non-linear method for hybrid reachability
Hung, Kwok Wang. "Identification of the EphA4-interacting proteins by yeast two-hybrid screening /." View abstract or full-text, 2006. http://library.ust.hk/cgi/db/thesis.pl?BICH%202006%20HUNG.
Full textKashuba, Elena. "Identification of EBNA binding cellular proteins, using yeast two-hybrid system /." Stockholm, 2002. http://diss.kib.ki.se/2003/91-7349-416-X/.
Full textMcGillewie, L. "Identification of novel ligands of WDR47, using yeast two-hybrid analysis." Thesis, Stellenbosch : University of Stellenbosch, 2009. http://hdl.handle.net/10019.1/3002.
Full textThe mammalian neocortex contributes to the increasing functional complexity of the mammalian brain, partly because of its striking organisation into distinct neuronal layers. The development of the neocortex has been well studied because disrupted neurodevelopment results in several human diseases. The basic principles of neocortical development have been well established for some time; however the molecular mechanisms have only recently been identified. One major advance in our understanding of these molecular mechanisms was the discovery of Reelin, an extracellular matrix protein that directs the migration of neurons to their final positions in the developing neocortex. Reelin is a large multi-domain protein that exerts its functions by binding to its ligands on the cell surface and initiating a signal transduction cascade that ultimately results in cytoskeletal rearrangements. Several investigations have been undertaken to elucidate the functions of each of these domains to gain a better understanding reelin’s functions. We have previously identified the WR40 repeat protein 47 (WDR47), a protein of unknown function, as a novel putative ligand for the N-terminal reeler domain of reelin. To gain better understanding into the functional significance of this interaction, the present study sought to identify novel WDR47- interacting proteins. In order to achieve this, a cDNA encoding a polypeptide that contains the two N-terminal domains of WDR47, i.e. the Lis homology and the C-terminal Lis homology domain (CTLH) was used as bait in a Y2H screen of a foetal brain cDNA library. Putative WDR47 ligands were subsequently verified using 3D in vivo co-localisation. Results of these analyses showed that SCG10, a microtubule destabilizing protein belonging to the stathmin family of proteins, interacted with the N-terminal of WDR47. The identification of SCG10 as a novel WDR47 interacting protein not only sheds some light on the role and function of WDR47 but also aids in a better understanding of the reelin pathway and cortical lamination. Moreover, the data presented here, may also provide researchers with new avenues of research into molecular mechanisms involved in neuronal migration disorders.
Huvanandana, Sanpachai. "A framework for a fast fingerprint identification using a hybrid system /." Thesis, Connect to this title online; UW restricted, 2002. http://hdl.handle.net/1773/5927.
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