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Journal articles on the topic 'IEDRA Model'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Varun, Shenoy, and S. Aithal P. "Quantitative ABCD Analysis of IEDRA Model of Placement Determination." International Journal of Case Studies in Business, IT and Education (IJCSBE) 1, no. 2 (2017): 103–13. https://doi.org/10.5281/zenodo.1133691.

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The current technological and digital era has always directed campus recruitment process towards eruption of paradigm shifts matching new systems of industrial workforce engagements. The dilemma of job seeking graduates today in campus has ever more convoluted towards the rapid changes in industry and employment market. IEDRA Model of Student Campus Placement Realization was a more comprehensive study undertaken by Shenoy & Aithal (2017) to resolve such a dilemma of students. Therefore here, a brief study is undertaken to discover practical viabilities, understand the usefulness, resourcef

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Varun, Shenoy, and Aithal Sreeramana. "A New IEDRA Model for Student Placement Realization." International Journal of Management, Technology, and Social Sciences (IJMTS) 2, no. 2 (2017): 20–27. https://doi.org/10.5281/zenodo.835611.

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Getting campus placement for employment even before completion of their course is a price achievement for graduating students. Even getting a first job immediately after course completion is a new dream start for young graduates. However, the complication exists when students in final graduating year at campus are very much unsure and uncertain about their chances of getting first job placement despite of all skill training and career counselling imparted owing to various factors. Therefore, to address and solve this dilemma of students, a new IEDRA (Interested, Eligible, Deserving, Registered

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Májek, Michal, and Matej Trtúšek. "Discovery of new tetrazines for bioorthogonal reactions with strained alkenes via computational chemistry." RSC Advances 14, no. 7 (2024): 4345–51. http://dx.doi.org/10.1039/d3ra08712c.

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Secondary orbital interaction in action: DFT calculations in combination with the distortion–interaction model help to uncover underlying factors responsible for the increased reactivity of sulfone- and sulfoxide-substituted tetrazines in iEDDA.

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Kimmel, April D., Zhongzhe Pan, Ellen Brazier, et al. "Development and calibration of a mathematical model of HIV outcomes among Rwandan adults: Informing achievement of global targets across sub-populations in Rwanda." PLOS One 20, no. 5 (2025): e0310662. https://doi.org/10.1371/journal.pone.0310662.

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Background We developed and calibrated the Central Africa-International epidemiology Databases to Evaluate AIDS (CA-IeDEA) HIV policy model to inform achievement of global goals, overall and across all sub-populations, in Rwanda. Methods We created a deterministic dynamic model to project adult HIV epidemic and care continuum outcomes, overall and for 35 subpopulations (age group, sex, HIV acquisition risk, urbanicity). Data came from the Rwanda cohort of CA-IeDEA, 2004–2020; Rwanda Demographic and Health Surveys, 2005, 2010, 2015; Rwanda Population-based HIV Impact Assessment, 2019; and liter

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Chen, Yang, Xiaoyan Sun, Dunwei Gong, and Xiangjuan Yao. "DPM-IEDA: Dual Probabilistic Model Assisted Interactive Estimation of Distribution Algorithm for Personalized Search." IEEE Access 7 (2019): 41006–16. http://dx.doi.org/10.1109/access.2019.2904140.

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Skrivankova, Veronika W., Stefanie Hossmann, Morna Cornell, et al. "Authorship inequalities in global health research: the IeDEA Southern Africa collaboration." BMJ Global Health 8, no. 12 (2023): e013316. http://dx.doi.org/10.1136/bmjgh-2023-013316.

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BackgroundThe International epidemiology Databases to Evaluate AIDS conducts research in several regions, including in Southern Africa. We assessed authorship inequalities for the Southern African region, which is led by South African and Swiss investigators.MethodsWe analysed authorships of publications from 2007 to 2020 by gender, country income group, time and citation impact. We used 2020 World Bank categories to define income groups and the relative citation ratio (RCR) to assess citation impact. Authorship parasitism was defined as articles without authors from the countries where the st

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Liu, Sixing, Yilin Zhang, Hao Wang, Fan Wu, Shifei Tao, and Yujing Zhang. "Efficient Design of Broadband and Low-Profile Multilayer Absorbing Materials on Cobalt–Iron Magnetic Alloy Doped with Rare Earth Element." Nanomaterials 14, no. 13 (2024): 1107. http://dx.doi.org/10.3390/nano14131107.

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Magnetic metal absorbing materials have exhibited excellent absorptance performance. However, their applications are still limited in terms of light weight, low thickness and wide absorption bandwidth. To address this challenge, we design a broadband and low-profile multilayer absorber using cobalt–iron (CoFe) alloys doped with rare earth elements (REEs) lanthanum (La) and Neodymium (Nd). An improved estimation of distribution algorithm (IEDA) is employed in conjunction with a mathematical model of multilayer absorbing materials (MAMs) to optimize both the relative bandwidth with reflection lo

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Damerow, Helen, Ralph Hübner, Benedikt Judmann, et al. "Side-by-Side Comparison of Five Chelators for 89Zr-Labeling of Biomolecules: Investigation of Chemical/Radiochemical Properties and Complex Stability." Cancers 13, no. 24 (2021): 6349. http://dx.doi.org/10.3390/cancers13246349.

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In this work, five different chelating agents, namely DFO, CTH-36, DFO*, 3,4,3-(LI-1,2-HOPO) and DOTA-GA, were compared with regard to the relative kinetic inertness of their corresponding 89Zr complexes to evaluate their potential for in vivo application and stable 89Zr complexation. The chelators were identically functionalized with tetrazines, enabling a fully comparable, efficient, chemoselective and biorthogonal conjugation chemistry for the modification of any complementarily derivatized biomolecules of interest. A small model peptide of clinical relevance (TCO-c(RGDfK)) was derivatized

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Tsondai, Priscilla R., Mary-Ann Davies, Thida Singtoroj, et al. "Creating a data collection and management platform to support measurement of adolescent HIV care transition processes within low- and middle-income countries: The GRADUATE project." PLOS Global Public Health 4, no. 8 (2024): e0002705. http://dx.doi.org/10.1371/journal.pgph.0002705.

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Few national programs and research cohorts within low- and middle-income countries (LMICs) document transition-related processes and outcomes for adolescents and young adults living with HIV (AYLH) transitioning to adulthood. Between 2017–2020, The Global fRAmework of Data collection Used for Adolescent HIV Transition Evaluation (GRADUATE) project convened a collaborative advisory group to identify key variables and definitions capturing the process, predictors, and outcomes across the transition period. In total, 114 variables identified as essential to measuring AYLH transition-related data

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Qiao, Zhanzhou, Guangsong Guo, and Yong Zhang. "An Interactive Estimation of the Distribution Algorithm Integrated with Surrogate-Assisted Fitness." Symmetry 15, no. 10 (2023): 1852. http://dx.doi.org/10.3390/sym15101852.

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To accurately model user preference information and ensure the symmetry or similarity between real user preference and the estimated value in product optimization design, an interactive estimation of a distribution algorithm integrated with surrogate-assisted fitness evaluation (SAF-IEDA) is proposed in this paper. Firstly, taking the evaluation information of a few individuals as training data, a similarity evaluation method between decision variables is proposed. Following that, a preference probability model is built to estimate the distribution probability of decision variables. Then, the

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Kumar, Nitin, R. K. Agrawal, and Ajay Jaiswal. "Incremental and Decremental Exponential Discriminant Analysis for Face Recognition." International Journal of Computer Vision and Image Processing 4, no. 1 (2014): 40–55. http://dx.doi.org/10.4018/ijcvip.2014010104.

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Linear Discriminant Analysis (LDA) is widely used for feature extraction in face recognition but suffers from small sample size (SSS) problem in its original formulation. Exponential discriminant analysis (EDA) is one of the variants of LDA suggested recently to overcome this problem. For many real time systems, it may not be feasible to have all the data samples in advance before the actual model is developed. The new data samples may appear in chunks at different points of time. In this paper, the authors propose incremental formulation of EDA to avoid learning from scratch. The proposed inc

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Harvey, David, Wessel Valkenburg, and Amara Amara. "Predicting malaria epidemics in Burkina Faso with machine learning." PLOS ONE 16, no. 6 (2021): e0253302. http://dx.doi.org/10.1371/journal.pone.0253302.

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Accurately forecasting the case rate of malaria would enable key decision makers to intervene months before the onset of any outbreak, potentially saving lives. Until now, methods that forecast malaria have involved complicated numerical simulations that model transmission through a community. Here we present the first data-driven malaria epidemic early warning system that can predict the 13-week case rate in a primary health facility in Burkina Faso. Using the extraordinarily high-fidelity data of infant consultations taken from the Integrated e-Diagnostic Approach (IeDA) system that has been

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Otaru, Sofia, Surachet Imlimthan, Mirkka Sarparanta, Kerttuli Helariutta, Kristiina Wähälä, and Anu Airaksinen. "Evaluation of Organo [18F]Fluorosilicon Tetrazine as a Prosthetic Group for the Synthesis of PET Radiotracers." Molecules 25, no. 5 (2020): 1208. http://dx.doi.org/10.3390/molecules25051208.

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Fluorine-18 is the most widely used positron emission tomography (PET) radionuclide currently in clinical application, due to its optimal nuclear properties. The synthesis of 18F-labeled radiotracers often requires harsh reaction conditions, limiting the use of sensitive bio- and macromolecules as precursors for direct radiolabeling with fluorine-18. We aimed to develop a milder and efficient in vitro and in vivo labeling method for trans-cyclooctene (TCO) functionalized proteins, through the bioorthogonal inverse-electron demand Diels-Alder (IEDDA) reaction with fluorine-18 radiolabeled tetra

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Kalema, N., B. Musick, S. Babirye, et al. "Trends in prevalent TB among persons enrolling for HIV care before and after ‘Test and Treat’ across East-Africa." IJTLD OPEN 2, no. 6 (2025): 359–65. https://doi.org/10.5588/ijtldopen.24.0687.

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<sec><title>BACKGROUND</title>In 2015, WHO recommended the global adoption of the ‘Test and Treat’ strategy (TTS) for all persons living with HIV (PLHIV). While TTS has improved viral suppression and reduced mortality, its impact on TB in PLHIV remains unclear.</sec><sec><title>METHODS</title>We assessed TB prevalence trends 48 months before and after TTS among PLHIV aged ≥18 years enrolling at HIV primary care sites affiliated with the East Africa International Epidemiology Databases to Evaluate AIDS (EA-IeDEA) consortium. We defined prevalent TB as b

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Desmonde, Sophie, Joycelyn Dame, Karen Malateste, et al. "Disparities in dolutegravir utilisation in children, adolescents and young adults (0–24 years) living with HIV. An analysis of the IeDEA Pediatric West African cohort." BMJ Global Health 10, no. 1 (2025): e016512. https://doi.org/10.1136/bmjgh-2024-016512.

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IntroductionWe describe the 24-month incidence of Dolutegravir (DTG)-containing antiretroviral treatment (ART) initiation since its introduction in 2019 in West Africa.MethodsWe included all patients aged 0–24 years on ART from nine clinics in Côte d’Ivoire (n=4), Ghana, Nigeria, Mali, Benin, and Burkina Faso. Baseline varied by clinic and was defined as date of first DTG prescription; patients were followed up until database closure/death/loss to follow-up (LTFU, no visit ≥7 months), whichever came first. We computed the cumulative incidence function for DTG initiation; associated factors wer

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Bredack, Christoph, Martin R. Edelmann, Edilio Borroni, Luca C. Gobbi, and Michael Honer. "Antibody-Based In Vivo Imaging of Central Nervous System Targets—Evaluation of a Pretargeting Approach Utilizing a TCO-Conjugated Brain Shuttle Antibody and Radiolabeled Tetrazines." Pharmaceuticals 15, no. 12 (2022): 1445. http://dx.doi.org/10.3390/ph15121445.

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Bioorthogonal pretargeted imaging using the inverse-electron-demand Diels–Alder (IEDDA) reaction between a tetrazine (Tz) and a trans-cyclooctene (TCO) represents an attractive strategy for molecular imaging via antibodies. The advantages of using a pretargeted imaging approach are on the one hand the possibility to achieve a high signal-to-noise ratio and imaging contrast; on the other hand, the method allows the uncoupling of the biological half-life of antibodies from the physical half-life of short-lived radionuclides. A brain-penetrating antibody (mAb) specific for β-amyloid (Aβ) plaques

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17

WANG, YAN-LIN, KE-YI WANG, WEN-YAN ZHAO, WAN-LI WANG, ZHUANG HAN, and ZI-XING ZHANG. "EFFECTS OF SINGLE CROUCH WALKING GAITS ON FATIGUE DAMAGES OF LOWER EXTREMITY MAIN MUSCLES." Journal of Mechanics in Medicine and Biology 19, no. 07 (2019): 1940046. http://dx.doi.org/10.1142/s0219519419400463.

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Single crouch walking gait (SCWG) is one of the main walking gaits when one of the legs is injured. However, the research on movement biomechanical characteristics (MBC) of lower extremity in SCWG has not been reported. So, the aim of this study is to analyze kinematics and main muscle fatigue damages of lower extremity in SCWG. Gaits data were collected with functional assessment biomechanics (FAB) system which applies the real-time wireless gait phase detection system, the movement function relations of joints of lower extremity were obtained by fitting the collected data in normal walking g

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Varun, Shenoy, and P. S. Aithal Dr. "ABCD Analysis of IEDRA Model of Placement Determination." December 6, 2022. https://doi.org/10.5281/zenodo.7403006.

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The current technological and digital era has always directed campus recruitment process towards eruption of paradigm shifts matching new systems of industrial workforce engagements. The dilemma of job seeking graduates today in campus has ever more convoluted towards the rapid changes in industry and employment market. IEDRA Model of Student Campus Placement Realization was a more comprehensive study undertaken by Shenoy & Aithal (2017) to resolve such a dilemma of students. Therefore here, a brief study is undertaken to discover practical viabilities, understand the usefulness, resourcef

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Shenoy, Varun, and P. S. Aithal. "Quantitative ABCD Analysis of IEDRA Model of Placement Determination." International Journal of Case Studies in Business, IT, and Education, December 10, 2017, 103–13. http://dx.doi.org/10.47992/ijcsbe.2581.6942.0019.

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The current technological and digital era has always directed campus recruitment process towards eruption of paradigm shifts matching new systems of industrial workforce engagements. The dilemma of job seeking graduates today in campus has ever more convoluted towards the rapid changes in industry and employment market. IEDRA Model of Student Campus Placement Realization was a more comprehensive study undertaken by Shenoy & Aithal (2017) to resolve such a dilemma of students. Therefore here, a brief study is undertaken to discover practical viabilities, understand the usefulness, resourcef

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Shenoy, Varun, and P. S. Aithal. "A New IEDRA Model for Student Placement Realization." International Journal of Management, Technology, and Social Sciences, July 28, 2017, 20–27. http://dx.doi.org/10.47992/ijmts.2581.6012.0021.

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Getting campus placement for employment even before completion of their course is a price achievement for graduating students. Even getting a first job immediately after course completion is a new dream start for young graduates. However, the complication exists when students in final graduating year at campus are very much unsure and uncertain about their chances of getting first job placement despite of all skill training and career counselling imparted owing to various factors. Therefore, to address and solve this dilemma of students, a new IEDRA (Interested, Eligible, Deserving, Registered

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21

Liu, Si‐Xing, Shi‐Fei Tao, Fan Wu, and Hao Wang. "Efficient Optimization of High‐Quality Microwave Metasurface Absorbers Using a Random Forest‐Assisted Improved Estimation of Distribution Algorithm." Advanced Materials Technologies, March 29, 2025. https://doi.org/10.1002/admt.202402075.

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AbstractThe design of microwave metasurface absorbers (MMAs) is complicated because numerous design parameters require high‐performance optimization algorithms. In this article, a random forest‐assisted improved estimation of distribution algorithm (RFIEDA) is proposed. RFIEDA aims to obtain a high‐quality MMA design with a limited number of exact expensive evaluations, where the geometric parameters and MMA unit patterns are both optimized. To address the mixed variable nature of geometric parameters and MMA unit patterns, a coding method is presented to transform geometric parameters into bi

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Annunziata, Alfonso, Sadek Amhaz, Jérémy Forté, et al. "Bioorthogonal Post‐Labeling Reveals Nuclear Localization of a Highly Cytotoxic Half‐sandwich Ir(III) Tetrazine Complex in Live Cells." ChemBioChem, April 3, 2025. https://doi.org/10.1002/cbic.202500090.

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Intracellular imaging of anticancer metallodrugs often relies on pre‐labeling with organic fluorophores, which significantly affects their physicochemical properties and intracellular distribution. On the other hand, the reported post‐labeling strategies based on click‐chemistry reactions require cell fixation and permeabilization. Here, we present a post‐labeling approach based on the catalyst‐free, inverse electron‐demand Diels‐Alder reaction (iEDDA) between a strained fluorescein‐tagged bicyclononyne derivative (BCN‐FAM) and half‐sandwich Ir(III) complexes containing bidentate ligands compr

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Su, Yixin, Wei Jiang, Fangquan Lin, et al. "Intrinsic and Extrinsic Factor Disentanglement for Recommendation in Various Context Scenarios." ACM Transactions on Information Systems, March 18, 2025. https://doi.org/10.1145/3722553.

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In recommender systems, the patterns of user behaviors (e.g., purchase, click) may vary greatly in different contexts (e.g., time and location). This is because user behavior is jointly determined by two types of factors: intrinsic factors , which reflect consistent user preference, and extrinsic factors , which reflect external incentives that may vary in different contexts. Differentiating between intrinsic and extrinsic factors helps learn user behaviors better. However, existing studies have only considered differentiating them from a single, pre-defined context (e.g., time or location), i

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Jamroz, Daria, Nathalie Fischer‐Durand, Marcin Palusiak, et al. "Inverse electron‐demand Diels‐Alder (iEDDA) bioorthogonal conjugation of half‐sandwich transition metallocarbonyl entities to a model protein." Applied Organometallic Chemistry 34, no. 4 (2020). http://dx.doi.org/10.1002/aoc.5507.

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25

Kern, Dóra, Allegra Lövei, Péter Kele, and Attila Kormos. "I Bind It That Way – Bioorthogonal Unmasking of Profluorescent Quinone Methides." European Journal of Organic Chemistry, July 2, 2024. http://dx.doi.org/10.1002/ejoc.202400541.

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Proof‐of‐concept studies for the bioorthogonally controlled generation of pro‐fluorescent quinone‐methides are presented here. The novel concept relies on a click‐to‐release tetrazine unit that chemically cages a pro‐fluorescent quinone methide precursor. On a synthetically readily accessible model compound we demonstrate that IEDDA reaction of the tetrazine with a TCO leads to the liberation of a pro‐fluorescent quinone methide, which is readily captured by nearby nucleophiles to form a fluorescent scaffold. Unlike in previous approaches to access bioorthogonally activatable fluorogenic probe

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Go, Eun Byeol, Jae Hun Lee, Jeong Haeng Cho, Na Hyun Kwon, Jong-il Choi, and Inchan Kwon. "Enhanced therapeutic potential of antibody fragment via IEDDA-mediated site-specific albumin conjugation." Journal of Biological Engineering 18, no. 1 (2024). http://dx.doi.org/10.1186/s13036-024-00418-3.

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Abstract Background The use of single-chain variable fragments (scFvs) for treating human diseases, such as cancer and immune system disorders, has attracted significant attention. However, a critical drawback of scFv is its extremely short serum half-life, which limits its therapeutic potential. Thus, there is a critical need to prolong the serum half-life of the scFv for clinical applications. One promising serum half-life extender for therapeutic proteins is human serum albumin (HSA), which is the most abundant protein in human serum, known to have an exceptionally long serum half-life. How

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Wu, Ruiqian, Ying Zhang, and Giorgos Bakoyannis. "Non‐Parametric Estimation for Semi‐Competing Risks Data With Event Misascertainment." Statistics in Medicine 44, no. 3-4 (2025). https://doi.org/10.1002/sim.10332.

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ABSTRACTThe semi‐competing risks data model is a special type of disease‐state model that focuses on studying the association between an intermediate event and a terminal event and proves to be a useful tool in modeling disease progression. The study of the semi‐competing risk data model not only allows us to evaluate whether a disease episode is related to death but also provides a toolkit to predict death, given that the episode occurred at a certain time. However, the computation of the semi‐competing risk models is a numerically challenging task. The Gamma‐Frailty conditional Markov model

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Chen, Lifang, Tao Wang, and Hongze Ge. "TMTrans: texture mixed transformers for medical image segmentation." AI Communications, August 29, 2023, 1–16. http://dx.doi.org/10.3233/aic-230089.

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Accurate segmentation of skin cancer is crucial for doctors to identify and treat lesions. Researchers are increasingly using auxiliary modules with Transformers to optimize the model’s ability to process global context information and reduce detail loss. Additionally, diseased skin texture differs from normal skin, and pre-processed texture images can reflect the shape and edge information of the diseased area. We propose TMTrans (Texture Mixed Transformers). We have innovatively designed a dual axis attention mechanism (IEDA-Trans) that considers both global context and local information, as

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Thomadakis, Christos, Constantin T. Yiannoutsos, Nikos Pantazis, et al. "The effect of HIV treatment interruption on subsequent immunologic response." American Journal of Epidemiology, April 12, 2023. http://dx.doi.org/10.1093/aje/kwad076.

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Abstract CD4 count recovery after antiretroviral treatment (ART) initiation has been thoroughly examined in HIV infection. However, immunologic response after ART restart following care interruption is less well studied. We compare the CD4 trends before disengagement from care and after ART re-initiation. Data were obtained from the East-Africa International epidemiology Databases to Evaluate AIDS (IeDEA) Collaboration (N= 62,534). CD4 trends before disengagement, during disengagement, and after ART re-initiation were simultaneously estimated through a linear mixed model with two subject-speci

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McDonagh, Anthony W., Brooke L. McNeil, Julie Rousseau, et al. "Development of a multi faceted platform containing a tetrazine, fluorophore and chelator: synthesis, characterization, radiolabeling, and immuno-SPECT imaging." EJNMMI Radiopharmacy and Chemistry 7, no. 1 (2022). http://dx.doi.org/10.1186/s41181-022-00164-1.

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Abstract Background Combining optical (fluorescence) imaging with nuclear imaging has the potential to offer a powerful tool in personal health care, where nuclear imaging offers in vivo functional whole-body visualization, and the fluorescence modality may be used for image-guided tumor resection. Varying chemical strategies have been exploited to fuse both modalities into one molecular entity. When radiometals are employed in nuclear imaging, a chelator is typically inserted into the molecule to facilitate radiolabeling; the availability of the chelator further expands the potential use of t

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Humphrey, John M., Philani Mpofu, April C. Pettit, et al. "Mortality Among People With HIV Treated for Tuberculosis Based on Positive, Negative, or No Bacteriologic Test Results for Tuberculosis: The IeDEA Consortium." Open Forum Infectious Diseases 7, no. 1 (2020). http://dx.doi.org/10.1093/ofid/ofaa006.

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Abstract Background In resource-constrained settings, many people with HIV (PWH) are treated for tuberculosis (TB) without bacteriologic testing. Their mortality compared with those with bacteriologic testing is uncertain. Methods We conducted an observational cohort study among PWH ≥15 years of age initiating TB treatment at sites affiliated with 4 International epidemiology Databases to Evaluate AIDS consortium regions from 2012 to 2014: Caribbean, Central and South America, and Central, East, and West Africa. The exposure of interest was the TB bacteriologic test status at TB treatment init

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Cho, Jeonghaeng, Byungseop Yang, Jae Hun Lee, et al. "In vivo study of newly developed albumin-conjugated urate oxidase for gout treatment." Arthritis Research & Therapy 25, no. 1 (2023). http://dx.doi.org/10.1186/s13075-023-03231-3.

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Abstract Background Exogenously providing engineered Uox with enhanced half-life is one of the important urate-lowering treatments for gout. The potential of PAT101, a recombinant human albumin (rHA)-conjugated variant, was evaluated and compared as a novel gout treatment through various in vivo studies with PAT101 and competing drugs. Methods PAT101 was produced by site-specific conjugation of rHA and Aspergillus flavus Uox (AfUox-rHA) through clickable non-natural amino acid (frTet) and Inverse electron demand Diels–Alder (IEDDA) reaction. In vivo pharmacokinetics, efficacy tests and in vitr

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Mathison, Megumi, Robert Gersch, Ahmed Nasser, et al. "Abstract 9748: In Vivo Cardiac Cellular Reprogramming Efficacy is Enhanced by Angiogenic Preconditioning of the Infarcted Myocardium." Circulation 126, suppl_21 (2012). http://dx.doi.org/10.1161/circ.126.suppl_21.a9748.

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A new in situ cellular reprogramming strategy demonstrated to convert fibroblasts into cardiomyocytes may represent an ideal cardiac regenerative therapy, obviating challenges inherent in stem cell implantation. We hypothesized that this strategy would be enhanced by angiogenic pretreatment of myocardial scar targeted by this treatment. Methods: The efficacy of lentivirus-mediated delivery of Gata4, Mef 2c and Tbx5 to transdifferentiate rat fibroblasts into induced cardiomyocytes (iCMs; Ieda et. al ., Cell . 2010; 142: 375-386) was validated by i n vitro FACS and immunofluorescence studies. Ad

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Tiendrebeogo, Thierry, Karen Malateste, Armel Poda, et al. "Impact of switching to a dolutegravir‐based regimen on body weight changes: insights from West African adult HIV cohorts." Journal of the International AIDS Society 27, no. 12 (2024). http://dx.doi.org/10.1002/jia2.26371.

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AbstractIntroductionAdverse metabolic effects related to dolutegravir (DTG) are increasingly reported as countries are adopting DTG‐based regimens as first‐line antiretroviral therapy (ART), but there is limited data from sub‐Saharan Africa. We explored changes in body weight pre‐ and post‐switch to a DTG‐based regimen and assessed the association between DTG switch and significant weight gain (SWG) defined as a ≥10% increase over a 12‐month period in people living with HIV (PLHIV) on ART in West Africa.MethodsWe first included all PLHIV followed in the IeDEA West Africa cohorts between Januar

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McCanney, James M. "INDUCED ELECTRIC DIPOLE RED SHIFT & RESTRUCTING COSMOLOGY." ASEAN Journal of Psychiatry, 2024, 01–16. https://doi.org/10.54615/2231-7805.2024.12(10).370.

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The material in the current paper was written between the years 1979 – 1981, when I was fortunate enough to be on the faculty in both the Physics and Mathematics Departments of Cornell University, Ithaca, NY. This was when vast amounts of data were flowing in from NASA space probes arriving at many of the planets, and I had access to it in addition to Cornell’s Library of Congress with all journal publications present in the stacks including rare books. NASA had a large presence at Cornell which was a depository of all NASA data and staff of many resident NASA scientists. These all played impo

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