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1
Edouart, Dimitri. "Imagerie flash laser (IFL) dans l'atmosphère turbulente : étude des fluctuations de l'éclairement dans le plan image." École nationale supérieure de l'aéronautique et de l'espace (Toulouse ; 1972-2007), 2004. http://www.theses.fr/2004ESAE0002.
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L'lmagerie Flash Laser (IFL) procède d’un principe d’imagerie active utilisant un laser impulsionnel et un détecteur matriciel pourvu d’une ‘porte temporelle’ de très courte durée. La réjection de la diffusion sur les aérosols atmosphériques et du fond ambiant offrent potentiellement des performances remarquables pour la détection et l'identification en environnement sévère (brouillard, précipitations. . . ). Les images obtenues dans l'atmosphère turbulente présentent cependant une modulation aléatoire appelée ‘tavelures’. La thèse propose une analyse de ce bruit dans divers régimes de fonctionnement. En particulier, elle identifie une forme de tavelures résultant d’un couplage entre le processus de diffusion lambertienne sur la surface de l’objet et la propagation à travers la turbulence atmosphérique. Une validation semi-quantitative de ce phénomène par simulations numériques est présentée. Par ailleurs, une méthode expérimentale permettant une caractérisation instantanée des propriétés statistiques de la modulation spatiale du faisceau d’éclairement introduit par la turbulence atmosphérique (la ‘scintillation’) est proposée.
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SANTOS, Breno Bittencourt. "Índice de Felicidade Local (IFL): Uma Proposta Teórico-Metodológica de Construção de Uma Medida de Desenvolvimento Social." Universidade Federal de Pernambuco, 2015. https://repositorio.ufpe.br/handle/123456789/16183.
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Previous issue date: 2015-07-30<br>CAPEs<br>A presente pesquisa alinha-se à perspectiva de Desenvolvimento Social, na qual se
propõe que, para além de critérios econômicos, o desenvolvimento deve ser mensurado
também a partir das dimensões sociais, políticas, culturais e emocionais relativas aos
indivíduos, grupos e territórios. Nesta perspectiva, os estudos da felicidade buscam
determinar o nível de satisfação dos indivíduos com suas próprias vidas, sendo levada
em consideração a análise de fatores socioeconômicos, demográficos, ambientais,
culturais e emocionais que podem apresentar relação com a felicidade do indivíduo. A
questão que norteou este estudo foi: quais são os fatores e em que medida eles podem
servir de parâmetros para a construção de uma medida de desenvolvimento social
baseada na mensuração da felicidade? O objetivo geral da pesquisa foi construir uma
proposta teórico-metodológica de medida de desenvolvimento social baseada na
felicidade, intitulada de Índice de Felicidade Local (IFL) e aplicar o IFL a uma amostra
populacional composta por habitantes dos municípios de Cabo de Santo Agostinho e
Ipojuca. Para isso, foram utilizados procedimentos estatísticos variados, especialmente a
técnica de análise de regressão multivariada, testes de correlação e testes de diferenças
de médias. Como resultados verifica-se que a população apresenta altos índices de
desigualdade socioeconômica e vulnerabilidade social, especialmente no que tange à
escolaridade, aos rendimentos dos trabalhadores e às posições no mercado de trabalho.
Neste estudo, observou-se que os indicadores de bem-estar subjetivo apresentam
maiores inter-relações com os níveis de felicidade dos indivíduos do que os indicadores
objetivos de bem-estar social. Dentre os indicadores de bem-estar subjetivos analisados,
constata-se que os indicadores relativos à satisfação com o poder de compra/ capacidade
de consumo e à satisfação com as relações familiares e de amizade são os que
apresentam maior influência na felicidade dos indivíduos. Estes resultados demonstram
que, no contexto analisado, a felicidade tende a ser influenciada por aspectos materiais e
não materiais de condições de vida. Por fim, verifica-se que, dentre os grupos
populacionais investigados, os imigrantes tendem a apresentar piores condições de bemestar
subjetivo e de felicidade que os não migrantes.<br>This research is aligned with the Social Development perspective, which proposes that,
in addition to economic criteria, the development must be measured also from social,
political, cultural and emotional concerning to individuals, groups and territories. On
this perspective, the happiness studies seek to determine the level of satisfaction of
individuals with their own lives, being taken into consideration the analysis of socioeconomic,
demographic, environmental, cultural and emotional factors that can present
connections with the happiness of the individuals. The question that guided this study
was: what are the factors and how they can serve as parameters for the construction of
a social development measure based on measuring happiness? The overall objective
was to build a theoretical and methodological proposal for social development measure
based on happiness, titled Local Happiness Index (LHI) and apply the LHI to a
population sample of inhabitants of the municipalities of Cabo de Santo Agostinho and
Ipojuca. For this, various statistical procedures were used, especially the multivariate
regression analysis technique, correlation tests and tests of mean differences. As a
result it turns out that the population has high rates of socioeconomic inequality and
social vulnerability, especially with regard to education, the income of workers and
positions in the labor market. On this study, the subjective well-being indicators have
greater inter-relations with the happiness levels of individuals than objective indicators
of social well-being. Among the subjective well-being indicators analyzed, it appears
that the indicators regarding satisfaction with the purchasing power/consumption
capacity and to meet with the family and friendship relationships are those with greater
influence in the happiness of individuals. These results demonstrate that in the context
analyzed, happiness tends to be influenced by material aspects and not material living
conditions. Finally, it turns out that among the populations investigated, recent
immigrants tend to have less level of subjective well-being and happiness in comparison
with non-migrants.
3
Mizza, Daria. "Instructional technology, L2 writing theory, and IFL : a case-study conducted in a British university among tutors and students." Thesis, University of Warwick, 2008. http://wrap.warwick.ac.uk/1112/.
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This study reviews a series of theoretical models and educational experiences, in order to examine how some of the claims made in the existing literature regarding the role of IT - mainly computer technologies - in writing instruction play out in the case of Italian as a Foreign Language (IFL). With this purpose in mind, this study examines a specific context - three IFL modules taught at the University of Warwick - and uses relevant teaching and learning experiences as a case-study and data sample. By using qualitative analysis supported by some quantitative methodologies, this study triangulates data from questionnaires, semi-structured interviews, focus-groups, field notes, classroom observation rubrics, as well as classroom artefacts, including online resources and educational software used over the course of the academic years 2004-2005 and 2005-2006. The data collected is filtered through a tripartite framework - learning/instructional environment, IFL tutors, and IFL students - designed to address the need expressed in the literature for analysis of multiple dimensions in complex interactions (Abbott, 1997; Athanases and Heath, 1995; Ramanathan and Atkinson, 1999; Snyder, 1997). The salient themes which emerge from the study are the critical roles of IFL tutors' and IFL students' expectations as well as the framework of values underlying these, along with particular features of information technologies themselves, in shaping participants' experiences and practices with respect to IT and writing, sometimes in unanticipated ways. Finally, the study considers the ways in which the results of the present research support, contradict, or expand existing literature, especially in relation to a number of specific factors, such as: the type of IT used in writing instruction; the physical configurations of IT-enhanced classrooms; and students' as well as tutors' approaches to learning and teaching IFL writing with and without technology. While the present work, like many other studies in the field of SLA and L2 writing, does not provide complete answer to the complex questions of language learning, it highlights the importance of both the instructional environment as well as the participants' framework of values. Only then, IT will be able to potentially enhance language instruction and become an integral component of learning. This research raises new questions, providing the basis for further research in the area of SLA theory and pedagogy.
4
Tamponi, Anna Rita. "Mind sets and IFL : texts and tasks : a theoretical model acting as a link between Italian language acquisition, cultural categories and literary texts." Thesis, University College London (University of London), 2006. http://discovery.ucl.ac.uk/1445866/.
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The present research was carried out at UCL and may be considered an 'action-research', being the result of theoretical reflections and didactic applications. It originated in the observation that learning the Italian language was not perceived by ab initio students as connected to their personal and academic experiences. An initial hypothesis was formulated that an early introduction to literary texts accompanied by tasks could favour the interlanguage development in ab initio University students. Furthermore, this development, mainly as far as written production is concerned, might be facilitated in learners who are specifically guided and trained to elaborate a written input, which might be recognized by them as 'meaningful', thanks to noticing and attention management tasks, and to production tasks, which have a relevant influence on the re-organization of forms and meaning. In other words, this action-research aimed at verifying how written performance in ab initio students was activated by the Task Based Approach and reflected the integration of language and content through the acquisition of written skills in Italian. The method of the three year study (2002-05) can be described as a qualitative approach in any stage: pre-actional, i.e. selection of literary texts and of appropriate tasks actional, i.e. organization of texts and tasks into modules and collection of data post-actional, i.e. systematic analysis of students' productions and feedbacks. In order to carry out this action-research, a course was devised and was called Text and Task Course (TTC), in which literary texts were the starting point and the model necessary to process language through specific tasks. So linguistically easy literary extracts of about 300 words each have been selected to represent different written text types such as letters and dialogues, poems and ballads, narratives and descriptions, each of them dealing with topics familiar to the learners. Each text was accompanied and enhanced by pre-, while- and production tasks. Production tasks in particular favoured the re-elaboration of texts and combined representational structures with controlled attention. Measures for the assessment of written production during TTC were: Holistic Rating, which included fluency and creativity Accuracy Ratios, which included intelligibility index and error index Complexity Ratios, which included dependent and coordinate clauses per t-units ratio and re-elaboration of a model or text type. Each of these parameters have been analytically described and applied. In the light of these considerations, it seems consistent to claim that the positive results in written production, after a relatively short time of instruction, were influenced by the training Texts and Tasks learners (TTL) received in the TTC and their interlanguage development was favoured by the constant re-elaboration of written input. In conclusion, the initial hypotheses were confirmed and the Text and Task approach, under given circumstances, was validated.
5
Qin, Daoming. "Role of 16S Ribosomal RNA in Translation Initiation." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1299007063.
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Araújo, Weslei Silva de. "Das Escolas Técnicas Federais aos Institutos Federais: a licenciatura em Física no campus Goiânia do IFG." Universidade Federal de Goiás, 2016. http://repositorio.bc.ufg.br/tede/handle/tede/5983.
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Previous issue date: 2016-07-25<br>In this paper we sought to understand how the Degree in Physics in IFG Goiânia
campus is structured and what the perspective of teachers in the area, specifically
in the implementation of degree in Physics, and forward the changes in the
institution. The choice of this theme is due to the requirement stipulated by law
11.892 of December 29, 2008, the Federal Institutes of Education, Science and
Technology, in offering undergraduate courses, especially in the areas of Science
and Mathematics, despite its recognized expertise in professional education. Some
research has dealt with the theme of the presence of the degrees in FIs, discussing
the profile, the deployment and the challenges that they are consoli dated.
However, here we seek teachers' perception of the process. Characterized as a
qualitative study we used bibliographical research to survey the changes via legal
documents in the institution, as well as research on the site e -MEC for
recognizing the quantity of courses offered in this mode before and after the
creation of the IFs. For analysis of the survey responses a nd interviews with
teachers of Physical area of Goiânia the IFG campus, we used content analysis,
according to Bardin (2002). It was identified as perceived by teachers who: (i)
changes in the institution provided an expansion and internalization, even
disorderly; (Ii) the change in the teaching profession and school
mischaracterization with devaluation of technical education; (Iii) the course
designed to meet the law, structure and operation in construction, has a focus on
specific knowledge at the expense of teaching; (Iv) teachers work almost
exclusively in the classroom, with little or no research and extension activities.
These aspects lead to understand that there is still a lack of identity in I Fs after
implantation of degrees and forward the changes in this institutions.<br>Neste trabalho buscou-se compreender de que forma a Licenciatur a em Física no
campus Goiânia do IFG se estrutura e qual a perspectiva dos professores da área ,
especificamente, na implantação da licenciatura em Física , e frente as mudanças
ocorridas na instituição. A escolha deste tema se deve pela obrigatoriedade,
estipulada pela lei 11.892 de 29 de dezembro de 2008, dos Institutos Federais de
Educação, Ciência e Tecnologia, em ofertar cursos de licenciaturas,
principalmente nas áreas de Ciências e Matemática, apesar de sua reconhecida
competência na área de educação p rofissional. Algumas pesquisas têm tratado da
temática sobre a presença das licenciaturas nos IFs, discutindo o perfil, a
implantação e os desafios para que os mesmos sejam consolidados. No entanto,
aqui buscamos a percepção dos professores sobre todo o pr ocesso. Caracterizado
como um trabalho de abordagem qualitativa utilizou-se inicialmente de pesquisa
bibliográfica para levantamento das alterações ocorridas via documentos legais na
instituição, assim como pesquisa no site e -MEC para o reconhecimento do
quantitativo de cursos ofertados nesta modalidade antes e depois da cria ção dos
IFs. Para análise das respostas do questionário e das entrevistas realizadas com os
professores da área de Física, do campus Goiânia do IFG, utilizou-se a Análise de
Conteúdo, segundo Bardin (2002). Identificou-se, segundo a percepção dos
professores que: (i) as mudanças na instituição proporciona ram uma expansão e
interiorização, mesmo que desordenada ; (ii) a alteração na carreira do professor e
a descaracterização da escola com desvalorização do ensino técnico; (iii) o curso
criado para atender a lei, com estrutura e funcionamento em construção, possui
um enfoque no conhecimento específico em detrimento do pedagógico; (iv) os
professores atuam quase que exclusivamente em sala de aula, com poucas ou
nenhuma atividade de pesquisa e de extensão. Estes aspectos levam a entender que
há ainda uma falta de identidade nos IFs após a implantação das licenciaturas e
frente as mudanças ocorridas nesta s instituições.
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Ahlström, Margareta. "Hörselskadade barn i kommunikation och samspel /." Stockholm : Univ, 2000. http://www.lhs.se/iol/publikationer/.
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Engdahl, Ingrid. "Med barnens röst : ettåringar "berättar" om sin förskola /." Stockholm : Institutionen för individ, omvärld och lärande, Lärarhögskolan i Stockholm, 2007. http://www.lhs.se/iol/publikationer/.
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Rukavina, Ivan. "Cyber-physics intrinsic modelling for smart systems." Thesis, Compiègne, 2021. http://bibliotheque.utc.fr/EXPLOITATION/doc/IFD/2021COMP2581.
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Dans le cadre de cette thèse, une approche de calcul de couplage multi-échelle et multi-physique en 2D et en 3D est présentée. La modélisation multi-échelle d’une structure consiste de l’échelle macro qui représente la réponse homogénéisée de la structure entière, tandis que l’échelle micro peut capturer les détails du comportement à la petite échelle du matériau, où des mécanismes inélastiques, tels que la plasticité ou l’endommagement, peuvent être pris en compte. L’intérieur de chaque macro-élément est rempli par le maillage à l’échelle micro qui s’y adapte entièrement. Les deux échelles sont couplées à travers le champ de déplacements imposé à l’interface. Le calcul par éléments finis est effectué, en utilisant une procédure de solution operator-split sur les deux échelles. En 2D, une discontinuité dans le champ de déplacements est introduite à l’échelle macro dans un élément fini Q4, pour pouvoir capturer l’adoucissement comportement d’un matériau piézoélectrique. Un degré de liberté supplémentaire qui représente le voltage est ajouté aux noeuds des macro-éléments de tétraèdre et d’hexaèdre en 3D. La poutre de Timoshenko comportant un modèle de commutation de polarisation est utilisée à l’échelle micro. Également, une formulation multi-échelle de Hellinger-Reissner a été développée et implémentée pour un simple patch test en électrostatique. La procédure proposée est mise en œuvre dans le logiciel de calcul par éléments finis FEAP - Finite Element Analysis Program. Pour simuler le comportement aux deux échelles, FEAP est modifié, et deux versions différentes du code sont obtenues - macroFEAP et microFEAP. Le couplage de ces codes est réalisé avec Component Template Library - CTL qui rend possible l’échange d’informations entre les deux échelles. Les capacités de cette approche multi-échelle en 2D et en 3D sont démontrées dans un environnement purement mécanique, mais aussi multi-physique. La formulation théorique et l’application algorithmique sont présentées, et les avantages de la méthode multi-échelle pour la modélisation des matériaux hétérogènes sont illustrés avec plusieurs exemples numériques<br>In this thesis, a multi-scale and multi-physics coupling computation procedure for a 2D and 3D setting is presented. When modeling the behavior of a structure by a multi-scale method, the macro-scale is used to describe the homogenized response of the structure, and the micro-scale to describe the details of the behavior on the smaller scale of the material where some inelastic mechanisms, like damage or plasticity, can be taken into account. The micro-scale mesh is defined for each macro-scale element in a way to fit entirely inside it. The two scales are coupled by imposing a constraint on the displacement field over their interface. The computation is performed using the operator split solution procedure on both scales, using the standard finite element method. In a 2D setting, an embedded discontinuity is implemented in the Q4 macroscale element to capture the softening behavior happening on the micro-scale. For the micro-scale element, a constant strain triangle (CST) is used. In a 3D setting, a macro-scale tetrahedral and hexahedral elements are developed, while on the micro-scale Timoshenko beam finite elements are used. This multi-scale methodology is extended with a multi-physics functionality, to simulate the behavior of a piezoelectric material. An additional degree of freedom (voltage) is added on the nodes of the 3D macro-scale tetrahedral and hexahedral elements. For the micro-scale element, a Timoshenko beam element with added polarization switching model is used. Also, a multi-scale Hellinger- Reissner formulation for electrostatics has been developed and implemented for a simple electrostatic patch test. For implementing the proposed procedure, Finite Element Analysis Program (FEAP) is used. To simulate the behavior on both macro and micro-scale, FEAP is modified and two different version of FEAP code are implemented – macroFEAP and microFEAP. For coupling, the two codes are exchanging information between them, and Component Template Library (CTL) is used. The capabilities of the proposed multi-scale approach in a 2D and 3D pure mechanics settings, but also multi-physics environment have been shown. The theoretical formulation and algorithmic implementation are described, and the advantages of the multi-scale approach for modeling heterogeneous materials are shown on several numerical examples
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Malak, Saly. "Optical localization of multiple micro-conveyors mobile over smart surfaces." Thesis, Compiègne, 2019. http://bibliotheque.utc.fr/EXPLOITATION/doc/IFD/2019COMP2526.
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Dans le contexte de la micro-robotique, cette thèse vise à développer une méthode de localisation et de suivi optique de micro-convoyeurs se déplaçant sur une surface. Le principe de la méthode de localisation proposée consiste à détecter un faisceau réfléchi sur le micro-convoyeur et à analyser ce signal optique pour obtenir les positions correspondantes. Les principaux éléments du système sont un rétroréflecteur à coin cube placé sur un micro-convoyeur et qui permet de réfléchir le signal optique dans sa direction incidente, un miroir MEMS qui permet de balayer la surface avec un éclairement laser, un séparateur de faisceau qui est un composant optique utilisé pour guider la lumière réfléchie vers un photodétecteur utilisé pour assurer la localisation et le suivi à travers l’exploitation du signal détecté par ce dernier. L’importance de la localisation est d’optimiser la trajectoire suivie par les micro-convoyeurs en contrôlant leur position et leur vitesse pour finalement pouvoir localiser les micro-convoyeurs avec une grande précision et éviter d’éventuelles collisions entre eux. Pour faire des tests expérimentaux et évaluer le capteur développé, la surface utilisée est une surface de micro-convoyage basée sur un principe électromagnétique, développée au laboratoire Roberval. Une calibration du système, en utilisant l’homographie, a été effectuée afin d’assurer la localisation et le suivi du micro-convoyeur pour après contrôler sa trajectoire et sa vitesse. Une localisation et un suivi simultané de deux micro-convoyeurs en utilisant un multiplexage temporel a été également développé et validé dans ce travail<br>This thesis aims to develop a method for optical localization and tracking of microconveyors moving over a surface in the context of micro-robotics. The principle of the proposed localization method consists of detecting a beam that is reflected on the micro-conveyor and analyzing this optical received signal to obtain the corresponding positions. The main elements of the system are a corner cube reflector, a MEMS mirror and a beam splitter. The corner cube is placed on the micro-conveyor in order to allow the optical signal to be reflected in its incident direction. The MEMS mirror allows the surface to be scanned with the laser. As for the beam splitter, it is an optical component used to guide the reflected light to a photodetector which is in turn used for localization and tracking through the exploitation of the signal that it detects. The important role of localization is to optimize the trajectory followed by the micro-conveyors. This could be achieved by controlling the respective position and speed of each of them in order to be finally able to localize the micro-conveyor with high precision and to avoid possible collisions between them. The surface used is a micro-conveying surface based on an electromagnetic principle, developed at the Roberval laboratory. The surface is used to perform experimental tests and to evaluate the developed sensor. A system calibration, using homography, was carried out in order to ensure the localization and tracking of the micro-conveyor, and then to control its trajectory and speed. Simultaneous localization and tracking of two micro-conveyors using time division multiplexing was also developed and validated in this work. An application of the thesis at the macroscopic scale is presented as well through applying free space optical communication between two mobile systems controlled by closed-loop optical tracking. Each system includes an active transmitter and a receiver (instead of a passive corner cube reflector in the case of the micro-conveyor). The system is driven by two servomotors which permit it to have free movement in three-dimensional space. The two modules must be aligned in order to be able to send and receive information by laser and thus communicate. In this case, a high-precision tracking system which is capable of aligning the two moving modules is required
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Bach, Dang Phong. "Development of a finite element strategy for the modeling of nano-reinforced materials." Thesis, Compiègne, 2020. http://bibliotheque.utc.fr/EXPLOITATION/doc/IFD/2020COMP2550.
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La modélisation des matériaux nano-renforcés nécessite de prendre en compte l’effet de taille induit par les phénomènes locaux à l’interface entre la nanoinclusion et la matrice. Cet effet de taille est interprété par une augmentation du rapport interface/volume et peut être pris en compte en introduisant une élasticité surfacique à l’interface. Alors que de nombreux travaux ont été développés du point de vue analytique, peu de contributions ont trait à la description numérique et à la mise en œuvre de cette élasticité surfacique dans la méthode des éléments finis (FEM). Nos études visent à développer des outils numériques efficaces basés sur la FEM pour la modélisation de nanocomposites. Dans un premier temps, nous évaluons les deux stratégies numériques existantes, à savoir l’approche XFEM et l’approche des éléments d’interface, dans la reproduction de l’effet de taille dans le processus d’homogénéisation. Deuxièmement, sur la base d’un test de performance des trois types de formulations d’E-FEM dans le cas de discontinuités faibles, nous proposons une formulation améliorée de SKON permettant d’intégrer l’effet d’une interface cohérente. Enfin, la modélisation numérique du comportement non linéaire des nanocomposites est étudiée. Lors de la première étape, une loi élastoplastique de type von Mises avec durcissement linéaire isotrope est considérée pour le volume, tandis que l’interface est considérée comme élastique linéaire<br>The modelization of nano-reinforced material requires to take into account the size effect caused by the local phenomena at the interface between the nano-inclusion and the matrix. This size effect is interpreted through an increase in the ratio interface/volume and can be taken into account by introducing a surface elasticity at the interface. Whereas a lot of works have been developed from the analytical point of view, few contributions are related to numerical description and implementation of such surface elasticity in Finite Element Method (FEM). Our studies aim to develop efficient numerical tools based on FEM for the modeling of nanocomposites. Firstly, we evaluate the two existent numerical strategies namely the XFEM approach and the Interface element approach in reproducing the size effect in the homogenization process. Secondly, based on a performance test on the three types of formulations of E-FEM for the case of weak discontinuity, we propose an enhanced SKON formulation allowing to incorporate the effect of a coherent interface. Finally, the numerical modeling on the nonlinear behavior of nanocomposites is investigated. In the first step, a von Mises type elastoplastic law with linear isotropic hardening is considered for the bulk while the interface is considered as linear elastic
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Dagmey, Aurélien. "Enrichissement d’huiles alimentaires riches en acides gras polyinsaturés, par des composés phénoliques d’origine naturelle, afin de les protéger de la peroxydation lipidique, en vue d’une encapsulation pour augmenter la durée de conservation de ces huiles." Thesis, Compiègne, 2020. http://bibliotheque.utc.fr/EXPLOITATION/doc/IFD/2020COMP2553.
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Les acides linoléique (LA) et α-linolénique (ALA) sont deux acides gras polyinsaturés. Ils sont indispensables à l’Homme car nous sommes incapables de les synthétiser in situ. Ces deux acides gras sont les représentants des oméga-6 (LA) et oméga-3 (ALA). Bien qu’ils soient indispensables et donc nécessaires, l’enjeu du ratio oméga-6/oméga-3 entre ces deux familles est également important à prendre en compte dans l’alimentation. Les habitudes de consommation des Français, ces trente dernières années, ont fait évoluer la balance en défaveur des oméga-3 par rapport aux oméga-6. Or un rééquilibre de la balance oméga-6/oméga-3 tend à diminuer les risques cardiovasculaires. Les huiles de lin et de cameline sont des cultures endémiques en France extrêmement riches en ALA. Elles sont les plus adaptées à une complémentation en oméga-3 d’origine végétale. Cependant, les hautes teneurs en acides gras polyinsaturés de ces huiles sont responsables de leurs faibles stabilités oxydatives. La consommation d’huiles ou de graisses oxydées n’est pas recommandée car elle peut apporter des molécules toxiques. Ainsi l’enjeu de ce projet était d’améliorer la durée de conservation d’huiles riches en acides gras polyinsaturés en valorisant les antioxydants extraits des tourteaux obtenus après trituration des graines. Parmi les molécules étudiées, l’acide gallique, l’acide caféique, le gallate de propyle ainsi que les pinorésinol et laricirésinol purifiées du lin ont montré un réel intérêt pour ralentir l’oxydation, tandis que le sécoisolaricirésinol s’est montré inefficace<br>Linoleic (LA) and α-linolenic (ALA) acids are two polyunsaturated fatty acids. They are essential for humans because we are unable to synthesize them in situ. These two fatty acids are the representatives of omega-6 (LA) and omega-3 (ALA). Although they are essential and therefore necessary, the issue of the omega-6 / omega-3 ratio between these two families is also important to take into account in the diet. The consumption habits of the French over the past thirty years have shifted the balance against omega-3s compared to omega-6s. Or a rebalancing of the omega-6 / omega-3 balance tends to reduce cardiovascular risks. Linseed and camelina oils are endemic crops in France extremely rich in ALA. They are the most suitable for supplementation with omega-3 of plant origin. However, the high contents of polyunsaturated fatty acids in these oils are responsible for their low oxidative stabilities. The consumption of oxidized oils or fats is not recommended because they can contribute toxic molecules. The aim of this project was to improve the shelf life of oils rich in polyunsaturated fatty acids by enhancing the antioxidant extracts of the cakes obtained after crushing the seeds. Among the molecules studied, gallic acid, caffeic acid, propyl gallate as well as pinoresinol and lariciresinol purified from flax showed a real interest in slowing down oxidation, while secoisolariciresinol was ineffective
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Welte, Anthony. "Spatio-temporal data fusion for intelligent vehicle localization." Thesis, Compiègne, 2020. http://bibliotheque.utc.fr/EXPLOITATION/doc/IFD/2020COMP2572.
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La localisation précise constitue une brique essentielle permettant aux véhicules de naviguer de manière autonome sur la route. Cela peut être atteint à travers les capteurs déjà existants, de nouvelles technologies (Iidars, caméras intelligentes) et des cartes haute définition. Dans ce travail, l'intérêt d'enregistrer et réutiliser des informations sauvegardées en mémoire est exploré. Les systèmes de localisation doivent permettre une estimation à haute fréquence, des associations de données, de la calibration et de la détection d'erreurs. Une architecture composée de plusieurs couches de traitement est proposée et étudiée. Une couche principale de filtrage estime la pose tandis que les autres couches abordent les problèmes plus complexes. L'estimation d'état haute fréquence repose sur des mesures proprioceptives. La calibration du système est essentielle afin d'obtenir une pose précise. En gardant les états estimés et les observations en mémoire, les modèles d'observation des capteurs peuvent être calibrés à partir des estimations lissées. Les Iidars et les caméras intelligentes fournissent des mesures qui peuvent être utilisées pour la localisation mais soulèvent des problèmes d'association de données. Dans cette thèse, le problème est abordé à travers une fenêtre spatio-temporelle, amenant une image plus détaillée de l'environnement. Le buffer d'états est ajusté avec les observations et toutes les associations possibles. Bien que l'utilisation d'amers cartographiés permette d'améliorer la localisation, cela n'est possible que si la carte est fiable. Une approche utilisant les résidus lissés a posteriori a été développée pour détecter ces changements de carte<br>Localization is an essential basic capability for vehicles to be able to navigate autonomously on the road. This can be achieved through already available sensors and new technologies (Iidars, smart cameras). These sensors combined with highly accurate maps result in greater accuracy. In this work, the benefits of storing and reusing information in memory (in data buffers) are explored. Localization systems need to perform a high-frequency estimation, map matching, calibration and error detection. A framework composed of several processing layers is proposed and studied. A main filtering layer estimates the vehicle pose while other layers address the more complex problems. High-frequency state estimation relies on proprioceptive measurements combined with GNSS observations. Calibration is essential to obtain an accurate pose. By keeping state estimates and observations in a buffer, the observation models of these sensors can be calibrated. This is achieved using smoothed estimates in place of a ground truth. Lidars and smart cameras provide measurements that can be used for localization but raise matching issues with map features. In this work, the matching problem is addressed on a spatio-temporal window, resulting in a more detailed pictur of the environment. The state buffer is adjusted using the observations and all possible matches. Although using mapped features for localization enables to reach greater accuracy, this is only true if the map can be trusted. An approach using the post smoothing residuals has been developed to detect changes and either mitigate or reject the affected features
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Vinardi, Carine. "Les défis du Lean à l’ère de la mondialisation et de l’industrie 4.0." Thesis, Compiègne, 2019. http://bibliotheque.utc.fr/EXPLOITATION/doc/IFD/2019COMP2500.
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Les entreprises multinationales ou transnationales, dont le nombre ne cesse d’augmenter, présentent la particularité d’avoir des salariés présents sur les différents continents, travaillant avec des rythmes et des cultures différentes. Dans le cadre des activités des entreprises, de plus en plus de salariés sont amenés à travailler en équipe multiculturelle et délocalisée. Ces mêmes entreprises sont à la recherche des meilleures performances opérationnelles et le déploiement de la démarche Lean est un levier reconnu d’obtention des meilleures performances de manière pérenne et ce depuis des dizaines d’années. En parallèle, depuis le développement d’internet et des nouvelles technologies, de nouveaux outils deviennent disponibles pour collecter et analyser les données ou encore pour produire. Au sein des entreprises et alors que les impacts sont souvent traités de manière séparés, c’est bien de manière systémique et en même temps qu’interagissent les dimensions culturelles, le déploiement du Lean et la mise en œuvre des outils liés à l’ère numérique. Dans un soucis ultime performance pérenne, c’est bien l’efficacité du système dans sa globalité dont il est question. Ce mémoire propose de faire un état des lieux séparé puis synchronisé et de proposer une aide à l’évaluation et à la mise en œuvre cohérente de l’ensemble des trois éléments<br>Multinational or transnational companies, whose number is constantly increasing, have the particularity of having employees working on different continents, having different rhythms and culture. More and more employees are required to work in multicultural and remote teams as part of their business activities. These same companies are looking for the best operational performance and the deployment of the Lean approach is a recognised lever for obtaining the best performance in a sustainable manner and has been for decades. In parallel, since the development of the Internet and digital technologies, new tools have become avaible to collect and analyse data or to manufacture. Within companies, while the impacts are often processed separately, it is indeed in a systemic way and at the same time that the cultural dimensions, the deployment of Lean and the implementation of tools linked to the digital era. With the ultimate aim of sustainable performance it is the efficiency of the system as a whole that is at stake. This thesis proposes to review of industrial situations, and to propose an support for the evaluation and consistent implementation of all three elements i.e culture, Lean and digitalization
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Mahut, Fabien. "Intégration des approches PLM et SLM pour le développement et la gestion des Systèmes Produit-Service en contexte automobile : proposition d’un cadre méthodologique." Thesis, Compiègne, 2019. http://bibliotheque.utc.fr/EXPLOITATION/doc/IFD/2019COMP2473.
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Ces travaux de thèse portent sur le développement et la gestion des Systèmes Produit-Service (ou Product-Service Systems, PSS) automobiles. Ces nouvelles offres intégrées de produits et services comportent des spécificités qui obligent à dépasser les démarches de développement des produits historiques considérés. Dans un état de l’art, ces travaux s’intéressent aux cadres méthodologiques pour le développement des PSS. Le premier niveau de ces cadres, focalisé sur les approches d’ingénierie, porte sur le Service Lifecycle Management (SLM) et son interaction avec le Product Lifecycle Management (PLM). Le deuxième niveau du cadre méthodologique s’intéresse aux processus et méthodes de développement des systèmes et PSS. Le troisième niveau du cadre méthodologique s’intéresse aux modélisations de PSS. La proposition est définie à travers les trois niveaux du cadre méthodologique, en respect de 7 critères retenus pour l’ingénierie des PSS. Elle repose sur un schéma d’interaction entre le PLM et le SLM détaillé, supportant un processus de développement, intégrant les pratiques de gestion de la diversité et d’Ingénierie Système. L’ensemble est cohérent avec une modélisation des PSS intégrant les architectures système, et basé sur le FBS et le triplet Result-Ressource-Process essentiels à la description du service. Deux cas d’étude ont permis d’expérimenter cette proposition. Le premier cas d’étude, portant sur un PSS existant et maitrisé, s’est traduit en la spécification d’un outil d’amélioration de la qualité du service. Le deuxième cas d’étude porte sur un PSS de diagnostic connecté et permet d’illustrer la proposition pour supporter son déploiement dans l’entreprise<br>This research work is exploring the development and management of Product-Service Systems. These new integrated offers go along with specific issues which challenge the current product development strategies. Analyzing the academic literature on this matter, this work focuses on methodological frameworks for the development of PSS offers. The first level of these frameworks is about engineering approaches considers Service Lifecycle Management (SLM) and Product Lifecycle Management (PLM) interactions. The second level is about specific systems or PSS development processes and methods. The third and last level challenges the definitions of a PSS model. Fed by this review, this work provides a coherent proposal for PSS development across these three levels, qualified by 7 analysis criterias. On the first level, a detailed PLM-SLM interaction scheme is proposed. It supports a development process on the second level, alongside a PSS model based on FBS and result-resource-process triplet as a matter for service adequate description. This proposal has been experimented through two study cases. The first one, about an existing and mature PSS, enabled the development of a quality management tool. The second, about the development of a connected diagnostic PSS enabled to strengthen the illustration of the proposal for its adoption
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Paulukat, Jens. "Regulation of IL-18 binding protein by IFN-[gamma] [IFN-gamma]." [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=969682123.
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Tancred, Linda. "Mechanisms of the intracellular survival of Francisella tularensis." Doctoral thesis, Umeå universitet, Klinisk bakteriologi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-45869.
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Francisella tularensis is a gram-negative, highly virulent, intracellular bacterium which causes the zoonotic disease tularemia. The subspecies tularensis and holarctica are clinically important, and the former is the more virulent. The intracellular lifestyle of F. tularensis is not completely understood, but after uptake in monocytes, the bacterium escapes from the phagosome within hours and replicates massively in the cytosol. The escape is dependent on factors encoded by the Intracellular Growth Locus (igl) operon, located in the Francisella Pathogenicity Island, FPI. The thesis was aimed to clarify and understand the interaction of F. tularensis strains with the endosomal pathway of monocytic cells in general and the roles of the Igl proteins and the global regulator MglA for this interaction in particular. A focus has also been to elucidate the roles of reactive oxygen and nitrogen species for the intracellular host-parasite interaction. We show that mutants in the IglB, IglC, or IglD proteins or their regulator MglA of the live vaccine strain, LVS (subspecies holarctica), all demonstrated reduced replication rates and lowered cytopathogenicity compared to the wild type in a J774 mouse macrophage cell model. Colocalization with LAMP-1 was significantly increased for the IglC, IglD and MglA mutants compared to LVS. This indicated an impaired ability to escape into the cytoplasm, while at the same time they, like LVS, partly prevented fusion with lysosomes. IFN-γ activation of the J774 host cells prior to infection had a bactericidal effect on LVS and all of the mutants, though the cidal effect was significantly more pronounced for the mutants. Following IFN-γ activation, a majority of the mutant-containing phagosomesfused with lysosomeswhile LVS remained localized in the cytosol without significantly increased interactions with the endosomal pathway. Previous studies have revealed that IFN-γ activation of F. tularensis-infected macrophages leads to control of infection but conclusions about the importance of reactive nitrogen and oxygen species on bacterial killing are inconsistent. We found that the growth inhibition resulting from IFN-γ activation could not be attributed to an increased oxidative burst since PMA-induced superoxide production was still inhibited by LVS to the same extent as in non-activated macrophages. On the other hand, reactive nitrogen species may in part have contributed to the cidal effect. To further assess the role of reactive nitrogen species to the killing of F. tularensis, nitric oxide was administrated exogenously to J774 cells infected with LVS. This led to significant killing of intracellular LVS with a concomitant increased phagosomal localization and downregulation of the virulence gene regulator mglA. These effects were reversed by addition of a peroxynitrite decomposition catalyst. A spontaneous avirulent mutant of subspecies tularensis, strain FSC043, was previously demonstrated to provide protective immunity in mice. Here, microscopic analyses of the strain revealed an unusual intracellular localization with a delayed phagosomal escape. This may account for the low virulence, while at the same time FSC043 remains immunogenic and thereby confers protection. The igl operon is intact in strain FCS043 and we hypothesize that a defect in the FPI gene pdpC contributed to the observed phenotype. Altogether, this thesis work demonstrates the importance of the mglA and igl genes for the virulence of F. tularensis and specifically their important roles for a functional phagosomal escape and inhibition of the host cell oxidative burst. Also, addition of exogenous nitric oxide likely leads to formation of peroxynitrite intracellularly, a reactive molecule which confines the bacterium to the phagosome and confers a significant bactericidal effect on intracellular F. tularensis.
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Chen, Shu. "Studies on interferon (IFN) induction and isolation of IFN-inducing mutant viruses." Thesis, University of St Andrews, 2011. http://hdl.handle.net/10023/1678.
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The interferon (IFN) system is a powerful antiviral defense system. Host cell pattern recognition receptors (PRRs) recognise pathogen-associated molecule patterns (PAMPs) which when activated, lead to the transcription of the IFN-β gene. As a consequence IFN is secreted from the cell and activates the JAK-STAT pathway to up-regulate the transcription of IFN-stimulated genes (ISGs). The products of many ISGs inhibit viral replication and cell proliferation. Viruses encode IFN antagonists that dampen down the IFN response, making it less effective. However, within a virus population, there are always likely to be naturally occurring mutant viruses that have lost the ability to circumvent the host IFN response, and if isolated, these viruses would be unlikely to cause severe disease in the host and may therefore be developed as live attenuated virus vaccine candidates. To develop a methodology to rapidly isolate IFN-inducing mutant viruses, we generated an A549 reporter cell-line in which expression of GFP was driven by the IFN-β promoter. Using this cell-line, we show that the number of cells that became positive for GFP correlated with the amount of IFN secreted by the infected cells and the number of defective interfering (DI) particles within the virus preparations. However, we were unable to isolate IFN-inducing mutant viruses using the A549/pr(IFN-β).GFP cell-line(s). Possible reasons for this may be either that, in cells infected by IFN-inducing mutant viruses, an antiviral state was established independent of IFN that prevented virus replication in the reporter cells in which the IFN-β promoter was activated; or the viruses that activated the IFN-β promoter were DIs only which were not be able to replicate without non-defective helper viruses. A549/pr(IFN-β).GFP cells are also being used for high throughput assays to screen chemical libraries for compounds that block IFN induction. Such compounds may be potential candidates for anti-inflammatory drugs.
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Goodsall, Timothy Mark. "The swift IFU Detector system and IFU observations of z~3 galaxies." Thesis, University of Oxford, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.510964.
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Cai, Di. "IfD - information for discrimination." Thesis, University of Glasgow, 2004. http://theses.gla.ac.uk/3972/.
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The problem of term mismatch and ambiguity has long been serious and outstanding in IR. The problem can result in the system formulating an incomplete and imprecise query representation, leading to a failure of retrieval. Many query reformulation methods have been proposed to address the problem. These methods employ term classes which are considered as related to individual query terms. They are hindered by the computational cost of term classification, and by the fact that the terms in some class are generally related to some specific query term belonging to the class rather than relevant to the context of the query. In this thesis we propose a series of methods for automatic query reformulation (AQR). The methods constitute a formal model called IfD, standing for Information for Discrimination. In IfD, each discrimination measure is modelled as information contained in terms supporting one of two opposite hypotheses. The extent of association of terms with the query can thus be defined based directly on the discrimination. The strength of association of candidate terms with the query can then be computed, and good terms can be selected to enhance the query. Justifications for IfD are presented from several aspects: formal interpretations of information for discrimination are introduced to show its soundness; criteria are put forward to show its rationality; properties of discrimination measures are analysed to show its appropriateness; examples are examined to show its usability; extension is discussed to show its potential; implementation is described to show its feasibility; comparisons with other methods are made to show its flexibility; improvements in retrieval performance are exhibited to show its powerful capability. Our conclusion is that the advantage and promise IfD should make it an indispensable methodology for AQR, which we believe can be an effective technique for improvement in retrieval performance.
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Hofmann, B. "On Ill-Posedness and Local Ill-Posedness of Operator Equations in Hilbert Spaces." Universitätsbibliothek Chemnitz, 1998. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-199801185.
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In this paper, we study ill-posedness concepts of nonlinear and linear inverse problems
in a Hilbert space setting. We define local ill-posedness of a nonlinear operator
equation $F(x) = y_0$ in a solution point $x_0$ and the interplay between the nonlinear
problem and its linearization using the Frechet derivative $F\acent(x_0)$ . To find an
appropriate ill-posedness concept for the linarized equation we define intrinsic
ill-posedness for linear operator equations $Ax = y$ and compare this approach with
the ill-posedness definitions due to Hadamard and Nashed.
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Hering, Annette. "Analysen zur IFN-[gamma]-Induktionskinetik [IFN-gamma-Induktionskinetik] von humanen naiven Th-Zellen." [S.l.] : [s.n.], 2002. http://www.diss.fu-berlin.de/2002/170/index.html.
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Westberg, Anna. "Scoutskjortan : mer än ett klädesplagg /." Stockholm : Lärarhögsk, 2004. http://www.lhs.se/iol/publikationer/IOLrapport_pdf/IOL.Forskning24.pdf.
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Tranter, Rhys Edward. "Ill seen Ill said : trauma, representation and subjectivity in Samuel Beckett's post-war writing." Thesis, Cardiff University, 2014. http://orca.cf.ac.uk/59995/.
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Over the last two decades, our understanding of Samuel Beckett’s life and work has been expanded by an unprecedented number of biographies, memoirs and personal correspondence published for the first time. As a result, academic research has been able to plot a series of connections between the writer’s literary work and the cultural and historical moments that shaped it. Beckett has been hailed as a poet whose work engages like no other with the atrocities of the Second World War. This thesis takes as its starting point an issue that often arises in evaluations of the writer, but which has never before been explored in detail: the theme of trauma. With reference to the work of prominent contemporary theorists, this project elucidates what we mean by the term trauma, and why it can be useful to our understanding of Samuel Beckett’s work. Drawing on the writings of Sigmund Freud, Cathy Caruth, and others, this thesis diagnoses traumatic symptoms and gestures in Beckett’s post-war writing. It identifies the role that ‘acting out’ and ‘working through’ plays in some of his late theatrical texts. And, moreover, the thesis begins to trace the role that trauma can play in our understanding of language and meaning. Adopting a broadly poststructuralist view, this study engages with texts by Maurice Blanchot and Jacques Derrida to ask how trauma challenges the status of language and the Western humanist subject. It will demonstrate how how trauma problematises our understanding of walking and thinking in Beckett’s post-war prose; where the presence of live theatrical production is unsettled by traumatic repetition; and why Beckett’s plays for radio undermine our expectations of twentieth-century modernity. While charting the way that Beckett uses and adapts traumatic themes and ideas, the thesis observes how the term signals a broader crisis in Western humanist understandings of time, place and identity.
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Der, Sandy D. "Regulation of IFN-Ã expression." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape16/PQDD_0001/NQ27908.pdf.
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Shravat, Aneesh. "Making sense of ill health." Thesis, City University London, 2011. http://openaccess.city.ac.uk/1175/.
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All the work in this portfolio is concerned with making sense of ill health. In particular it primarily focuses on person centred approaches to working with people that have either been affected directly or indirectly by ill health. The research focuses on person centred therapists’ subjective experiences of working with older adults who have cancer. The aim is to draw the focus to Counselling Psychologists and other mental health professionals to the experiences of person centred therapists of working with older adults with cancer, as no research has been undertaken in this area previously. It is hoped that the research can illuminate an area in which little research has been undertaken previously. The Critical Literature Review focuses on the literature, which evaluates the effectiveness of psychological interventions for older adults with chronic illness. In particular it outlines the paucity that exists in this research and the possible reasons for this. It is hoped that this can focus mental health professionals on the need for more research to inform future interventions and indeed future debate on the effectiveness of different psychotherapeutic models in order provide clarity for professionals working with this client group. The Case Study provides an example of using a person centred approach with a client whose father has cancer. It provides an insight in to how the focus of the therapeutic relationship can help a client focus on underlying feelings and help see his situation with more clarity. It also provides an example of seeing a client’s lived experience descriptively as opposed to being seen as an expert trying to explain or analyse these experiences.
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Han, Thang Sieu. "Body morphology and ill health." Thesis, University of Glasgow, 1997. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.711896.
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Chau, Teresa C. "IFE, an interactive formula editor." FIU Digital Commons, 1988. http://digitalcommons.fiu.edu/etd/2117.
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IFE, the Interactive Formula Editor is an experimental system designed, developed and implemented to propose a different approach to handle mathematical formulae. Its main characteristics are: (1) Interactive creation and edition of a mathematical formula, (2) Tex-form output for a printed version of a formula, and (3) Ability to generate a new set of characters by means of a character editor.
Mathematical symbols are provided and adjusted by the system, automatically. The system also, guides the user during the formula description because it knows the syntax of the graphical representation.
The system seems to be complete and perform well. The listing of the program is included, as are suggestions for further development.
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Kühnle, Simone. "The reconstitution of immunocompetence by GM-CSF or (IFN-g) [(IFN-gamma)] after pharmacological suppression." [S.l.] : [s.n.], 2000. http://deposit.ddb.de/cgi-bin/dokserv?idn=961227540.
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Zurney, Jennifer Michelle. "Cardiac Cell Type-Specific Differences in the Interferon (IFN) Response, and Reovirus Repression of IFN." NCSU, 2008. http://www.lib.ncsu.edu/theses/available/etd-06302008-141954/.
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Viral myocarditis is an important human disease associated with a wide variety of viruses. The cardiac damage and inflammation associated with viral myocarditis can be immune mediated and/or due to direct cytopathic effect. Reovirus-induced myocarditis reflects direct virus-mediated apoptosis of cardiac cells, providing an excellent model to study direct cytopathic effect in the heart. Previous work has found interferon-beta (IFN) to be an important determinant for protection against viral myocarditis. Importantly, IFN signals through the Jak-STAT pathway to induce the expression of interferon-stimulated genes (ISGs) and establish an antiviral state. First, we investigated the underlying mechanisms of the IFN response in these cardiac cells. We found that high basal IFN-beta expression in cardiac myocytes protects this vulnerable, nonreplenishable cardiac cell type, while high basal expression of interferon alpha receptor 1 and latent Jak-STAT components in adjoining cardiac fibroblasts renders these cells more responsive to IFN and prevents them from inadvertently serving as a virus reservoir. This provides the first evidence for an integrated network of cell-type-specific innate immune components for organ protection. Next, we investigated whether particular reovirus strains were able to repress IFN signaling. We found that the mildly myocarditic reovirus, T1L, but not the nonmyocarditic reovirus, T3D, could repress IFN induction of ISGs and that this repressor function is determined by the M1 gene of T1L. Infection with T1L or reassortant or recombinant viruses containing the T1L M1 gene results in accumulation of IRF9 in the nucleus; an effect not previously described for any virus. The M1 gene has also previously been identified as a determinant of virus strain-specific differences in the IFN response, and the M1 gene and the IFN response have been identified as determinants of virus strain-specific differences in induction of murine myocarditis. Here, we find that virus-induced myocarditis is associated with repression of IFN function, providing new insights into the pathophysiology of this disease. Together, these data provide the first report of an increase in IRF9 nuclear accumulation associated with viral subversion of the IFN response, and provide evidence that virus strain-specific differences in IFN antagonism are a determinant of disease.
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Reich, Julie A. "Perceptions of Parental Differential Treatment: Correlates in Chronically Ill and Non-Ill Samples of Children." [Tampa, Fla.] : University of South Florida, 2003. http://purl.fcla.edu/fcla/etd/SFE0000063.
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BAZALGETTE, COURREGES LACOSTE GREGORY. "Spectroscopie de tres haute resolution de icl. Photodissociation et collision de la molecule de icl orientee." Toulouse 3, 1997. http://www.theses.fr/1997TOU30224.
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Spectroscopie de tres haute resolution de icl : nous avons applique une technique de spectroscopie de saturation a la transition a-x de icl pour eliminer l'effet doppler residuel et determiner sa structure hyperfine. La faible largeur naturelle de cette transition confere a cette experience un interet metrologique. Les resultats que nous avons obtenu sur icl permettent de resoudre les structures hyperfines de l'iode et du chlore, contrairement a la technique de spectroscopie conventionnelle ou la structure du chlore est masquee par l'effet doppler residuel. Ces resultats sont interessants car la structure hyperfine moleculaire caracterise de maniere tres precise la liaison chimique. Photodissociation et collision de la molecule de icl orientee : h. J. Loesch a montre, en 1990, comment orienter l'axe moleculaire en appliquant un champ electrique intense sur des molecules polaires tres froides en rotation, produites par expansion supersonique. Plusieurs experiences de collisions ont ainsi ete realisees, mais l'orientation n'a jamais ete mesuree directement. Nous avons effectue une telle mesure sur un jet moleculaire de icl grace a une experience de photodissociation. Le jet de icl ensemence dans l'argon a ete optimise afin d'obtenir simultanement une tres basse temperature rotationnelle et une faible fraction de icl dans des complexes. Les atomes d'iode produits par la photodissociation et emis dans la direction du champ electrique sont detectes par spectrometrie de masse. Cette experience mesure l'orientation de l'axe moleculaire en fonction du champ applique et donne un acces direct au signe du moment dipolaire de icl dans l'etat x. Nous avons modelise l'experience par un calcul monte-carlo et mis en evidence d'importants effets non lineaires en champ electrique du processus d'orientation. D'autre part, nous avons etudie la theorie des effets de reorientation moleculaire lors d'une collision entre un atome et une molecule orientee par un champ electrique intense.
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Nilsson, Andreas. "IBL in GUI for mobile devices." Thesis, Linköpings universitet, Institutionen för teknik och naturvetenskap, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-93048.
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Mobile phones are here to stay, and the interaction with them is an evolving process. Designing software for mobile devices poses new challenges not seen in desktop computer environments. Screen size, performance and inputs, are just a few areas where they significantly differ. Although, intriguingly the gap between them is narrowing. Devices are now able to do things previously only restricted to PCs. The graphics chip integrated with high-end devices of today and tomorrow has capabilities worth exploring. With more power and advanced shader support, techniques such as image based lighting becomes worth exploring. To solve the problem described in this thesis I built a framework for image processing. This framework is further described indirectly throughout the report and is available upon request. The framework is never the focus of the report since any framework should suffice and the developed framework should not hinder the reader’s own experimentations. The purpose of this thesis is to see whether image based lighting (IBL) and image based rendering (IBR) is feasible with a mobile phone, as well as explore which applications it would suit for. Also, examining if it can be combined with high dynamic range imaging (HDRI) to enhance the user experience. Both IBL/IBR and HDRI might be new terms for the reader; if so I encourage you to read 2.2 for a deeper understanding.
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Lai, Sum-yee Sumi, and 黎心怡. "Equal opportunities for the mentally-ill." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B44569853.
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Shiu, Stephen Yuen Wing. "Molecular studies of louping ill virus." Thesis, University of Oxford, 1991. http://ora.ox.ac.uk/objects/uuid:949ac059-3386-4435-90e1-15166075fd89.
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The genomic RNA encoding the structural proteins of louping ill, a tickborne flavivirus, was cloned and sequenced. Sequence comparisons of louping ill envelope protein showed greater homology with tick-borne than mosquito-borne flaviviruses and greater homology with the western than the far eastern subtype of tick-borne encephalitis virus. Louping ill and tick-borne encephalitis viruses are probably varieties of a common tick-borne ancestral virus. The average amino acid sequence diversity between members of the tick-borne serogroup was significantly lower than that of mosquito-borne serogroups, suggesting that tick-borne flaviviruses have been subjected to different evolutionary immune selection pressure from the mosquito-borne viruses. Using the published model of tick-borne encephalitis envelope protein and the derived sequence data on louping ill virus, three discontinuous peptides (amino acids 81-88, 207-212 and 230-234) which may represent critical molecular determinants within the receptor binding site of tick-borne flaviviruses, were identified. These peptides may provide a specific genetic marker for these viruses. Recombinant baculoviruses and vaccinia viruses containing cloned DNA, encoding either the envelope protein or the structural proteins of louping ill virus, were constructed. Glycosylated envelope protein, presented both inside and on the surface of insect and mammalian cells, was expressed by all four recombinant viruses. Differences in antigenic presentation of envelope protein were observed between envelope protein and structural protein constructs as well as between insect cell and mammalian cell expression systems. Despite the expression of epitopes known to elicit neutralizing and protective antibodies when present in authentic antigen, the recombinant envelope protein expressed by either baculovirus or vaccinia virus failed to induce, under the experimental conditions employed, either neutralizing or protective antibodies in both mice and rabbits against louping ill virus. Hence, louping ill envelope protein expressed by baculoviruses and vaccinia viruses was antigenically reactive but immunogenically inert.
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Woods, Valerie. "Work inequalities and musculoskeletal ill health." Thesis, University of Surrey, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.435101.
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Lai, Sum-yee Sumi. "Equal opportunities for the mentally-ill /." Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B22284394.
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Cisneros, Francisco. "Terminally ill and hospice residential settings." Theological Research Exchange Network (TREN), 1996. http://www.tren.com.
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Fabre, Maria I. "International comparison of critically ill patients." Thesis, Massachusetts Institute of Technology, 2017. http://hdl.handle.net/1721.1/112844.
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Thesis: M. Eng., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2017.<br>This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.<br>Cataloged from student-submitted PDF version of thesis.<br>Includes bibliographical references (page 26).<br>Severity of illness scores are useful in quality improvement for benchmarking care in the ICU and in research for risk-adjustment. [1] However, these scores lack generalizability beyond the patients on whom the scores were trained on. An international consortium, Global Open Source Severity of Illness Score (GOSSIS) Project, has put together various databases to create a definition of critical care severity independent of geographic and cultural data. [2] In order to combine the databases efficiently, 200 variables of interest were identified and extracted from the databases, when possible. Some variables showed different distributions throughout the databases that can be attributed to differences in medical practices and selection bias of hospitals. Thus, the predictive models that were trained in one database scored poorly when tested on a different database. Thus, a combination of the extracted variables from different databases with some necessary data manipulation should create a more generalizable severity of illness score.<br>by Maria I. Fabre.<br>M. Eng.
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Branco, Ricardo Garcia. "Stress response in critically ill children." Thesis, University of Cambridge, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.609718.
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Pina, Lígia Isabel Gomes de. "Esclerose múltipla: terapêutica com IFN-β". Master's thesis, [s.n.], 2012. http://hdl.handle.net/10284/3202.
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Trabalho apresentado à Universidade Fernando Pessoa, como parte dos requisitos para obtenção do grau de Mestre em Ciências Farmacêuticas<br>A esclerose múltipla (EM) é a doença crónica mais comum do sistema nervoso central (SNC) e é caracterizada pela destruição da mielina. Hoje em dia é objecto de inúmeras pesquisas para determinar com precisão as suas causas e definir um tratamento eficaz. A diferente susceptibilidade à doença entre homens e mulheres, negros e caucasianos, jovens e idosos e a distribuição geográfica díspar da EM parece sugerir uma interacção efectiva entre factores genéticos e ambientais. Apesar de ser uma doença auto-imune, o tratamento com imunossupressores ficou aquém das expectativas e começaram a utilizar-se imunomoduladores como o Interferão beta (IFN-β) de modo a reduzir a frequência e a gravidade dos surtos. Multiple sclerosis is the most common chronic disease of the central nervous system and is characterized by the destruction of myelin. Nowadays is subject of numerous studies to establish accurately the causes and define an effective treatment. The different susceptibility to disease between men and women, blacks and whites, young and old and unequal geographical distribution of MS appears to suggest an effective interaction between genetic and environmental factors. Although it is an autoimmune disease, treatment with immunosuppressive agents is still poor and it was initiated the use of immunomodulators such as interferon beta (IFN-β) to reduce the frequency and severity of the attacks.
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Garde, Maria Salomé. "Mentally ill homeless and companion pets." CSUSB ScholarWorks, 2003. https://scholarworks.lib.csusb.edu/etd-project/2186.
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The present study assessed the relationship between mentally ill homeless and their companion pets and questioned if the pets acted as a barrier for them to receive shelter and other services. The study also sought to find if pets acted as a communication tool between this population and society. themselves because they are mentally vulnerable and victims of a mental disorder.
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Robertson, Gillian. "Hypernatraemic gastroenteritis in critically ill children." Master's thesis, University of Cape Town, 2005. http://hdl.handle.net/11427/9261.
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Tran, Trinh, and Rifqa Al-sammaraie. "Användning av filformatet IFC i byggprojekt." Thesis, Malmö universitet, Fakulteten för teknik och samhälle (TS), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-20033.
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Byggnadsinformationsmodellering (BIM) kan utföras med olika programvaror som används av de olika aktörerna i ett byggprojekt. BIM medför flera fördelar för byggprocessen som till exempel modelleringsfördelar, tekniska fördelar och ekonomiska fördelar. Däremot är informationsöverföringen mellan olika 3D-program (interoperabilitet) ett problem och en av de största utmaningarna för BIM-användare idag. IFC är ett standardiserat (sedan 1997), öppet och neutralt filformat som möjliggör överföring av information mellan olika 3D-program. Syftet med denna studie var att undersöka hur hanteringen av information på IFC-format upplevs av olika aktörer som deltar i ett byggprojekt. Studien undersöker även utvecklingsmöjligheter av IFC-format utifrån användarnas perspektiv för att säkerställa smidigt och kvalitetssäkert informationsflöde i ett projekt. Frågeställningar som har behandlats är vilka möjligheter och hinder som IFC-format anses ha utifrån användarnas perspektiv, hur IFC upplevs och används av olika aktörer samt hur ett krav på att använda IFC-format upplevs av aktörer inom byggbranschen. I studien genomfördes en litteraturundersökning inom ämnet för att få förståelse för hantering av IFC-format i byggbranschen. Därefter genomfördes en kvalitativ undersökning där totalt sju aktörer från olika verksamheter intervjuades. Denna kompletterades med en kvantitativ under-sökning genom en enkätstudie. Slutsatsen i arbetet är att IFC-format är vanligt förekommande i byggprojekt. IFC-format upplevs som ett verktyg som möjliggör och underlättar kommunikation och samordning mellan modeller och discipliner. Däremot anser majoriteten av IFC-användare att IFC fortfarande är ett bristfälligt format. Litteraturstudien tillsammans med den kvantitativa och kvalitativa undersökningen visar att kunskapen om hantering av IFC-formatet brister inom byggbranschen vilket är en av anledningarna till informationsförlusterna. Flertalet av studiens deltagare var positivt inställda till att krav ställs på att IFC måste användas i byggprojekt, när formatet utvecklas ytterligare.<br>Building information modeling (BIM) can be carried out in various software applications that are used by the different actors in a construction project. However, interoperability problems are one of the biggest challenges for BIM users today. The purpose of this study was to investigate how IFC format management is experienced by different actors in a construction project. The study also examines development opportunities of IFC format from the user’s perspectives to ensure smooth and quality-assured information flow in a project. In this research, a literature study was carried out to gain an understanding of the management of IFC format at present. A qualitative and a quantitative study was also carried out, by conducting interviews with actors from different companies and collecting data through a survey. The conclusion is that IFC format is very common in construction projects. IFC format is a tool that enables and facilitates communication and coordination between models and disciplines. However, the majority of IFC users consider that the IFC is still a defective format. The participants were primarily optimistic of the fact of IFC being a requirement within the construction industry. However, believes that further development is needed before being implemented.
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Shyshkov, Andriy. "NUMERICAL SOLUTION OF ILL-POSED PROBLEMS." Kent State University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=kent1271700548.
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Neuman, Arthur James III. "Regularization Methods for Ill-posed Problems." Kent State University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=kent1273611079.
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Junger, Anette. "Barns upplevelse av intensiv familjeterapi (IFT)." Thesis, Ersta Sköndal Bräcke högskola, S:t Lukas utbildningsinstitut, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:esh:diva-6043.
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Rayborn, Kimberly Nicole Bryant. "Student perceptions of mentally ill offenders." Thesis, The University of Southern Mississippi, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10104495.
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<p> Since deinstitutionalization, the responsibility for mentally ill members of society has shifted to the criminal justice system in a process of trans-institutionalization or “criminalization of mental illness” (Slate & Johnson, 2013, p. 28). Though various groups have been studied to ascertain their perception of mentally ill individuals and offenders, previous research focuses largely on students of psychology, social work, and medicine. Little research has been conducted regarding the perceptions of criminal justice students toward mental illness, despite the increasing involvement of the criminal justice system in treating and handling mentally ill individuals in the past thirty years. This exploratory research serves as a replication to a study which was conducted by Thompson, Paulson, Valgardson, Nored, and Johnson (2014). </p>
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Larsen, Henrik Fred. "Assessment of chemical emissions in life cycle impact assessment : focus on low substances data availability and ecotoxicity effect indicators /." Department of Manufacturing, Engineering and Management, Technical University of Denmark, 2004. http://tempo.ipl.dtu.dk/ipl/upload/publ/PhD-thesis-rev.pdf.
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Yeung, Yee-yu. "An assessment of the implementation of social rehabilitation for the mentally ill." [Hong Kong : University of Hong Kong], 1993. http://sunzi.lib.hku.hk/hkuto/record.jsp?B13552983.
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