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Journal articles on the topic "IFML4"

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Lunova, Mariia, Jan Kubovciak, Barbora Smolková, Mariia Uzhytchak, Kyra Michalova, Alexandr Dejneka, Pavel Strnad, Oleg Lunov, and Milan Jirsa. "Expression of Interferons Lambda 3 and 4 Induces Identical Response in Human Liver Cell Lines Depending Exclusively on Canonical Signaling." International Journal of Molecular Sciences 22, no. 5 (March 4, 2021): 2560. http://dx.doi.org/10.3390/ijms22052560.

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Lambda interferons mediate antiviral immunity by inducing interferon-stimulated genes (ISGs) in epithelial tissues. A common variant rs368234815TT/∆G creating functional gene from an IFNL4 pseudogene is associated with the expression of major ISGs in the liver but impaired clearance of hepatitis C. To explain this, we compared Halo-tagged and non-tagged IFNL3 and IFNL4 signaling in liver-derived cell lines. Transfection with non-tagged IFNL3, non-tagged IFNL4 and Halo-tagged IFNL4 led to a similar degree of JAK-STAT activation and ISG induction; however, the response to transfection with Halo-tagged IFNL3 was lower and delayed. Transfection with non-tagged IFNL3 or IFNL4 induced no transcriptome change in the cells lacking either IL10R2 or IFNLR1 receptor subunits. Cytosolic overexpression of signal peptide-lacking IFNL3 or IFNL4 in wild type cells did not interfere with JAK-STAT signaling triggered by interferons in the medium. Finally, expression profile changes induced by transfection with non-tagged IFNL3 and IFNL4 were highly similar. These data do not support the hypothesis about IFNL4-specific non-canonical signaling and point out that functional studies conducted with tagged interferons should be interpreted with caution.
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Miyamura, Tatsuo, Tatsuo Kanda, Shingo Nakamoto, Makoto Arai, Masato Nakamura, Shuang Wu, Xia Jiang, et al. "IFNL4 ss469415590 Variant Is Associated with Treatment Response in Japanese HCV Genotype 1 Infected Individuals Treated with IFN-Including Regimens." International Journal of Hepatology 2014 (2014): 1–6. http://dx.doi.org/10.1155/2014/723868.

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Aim. Eradication of hepatitis C virus (HCV) is still challenging even if interferon- (IFN-) free regimens with direct-acting antiviral agents (DAAs) for HCV-infected individuals are available in clinical practice. IFNL4 is a newly described protein, associated with human antiviral defenses. We investigated whether IFNL4 ss469415590 variant has an effect on the prediction of treatment response in HCV-infected patients treated with IFN-including regimens.Patients and Methods. In all, 185 patients infected with HCV genotype 1 treated with peg-IFN plus ribavirin, with or without telaprevir, were genotyped for IFNL4 ss469415590. We retrospectively investigated whether the role of IFNL4 ss469415590 variant and other factors could predict sustained virological response (SVR) in Japanese patients infected with HCV genotype 1.Results. There were 65.7%, 31.5%, and 2.8% patients in the IFNL4 ss469415590 TT/TT, TT/-G, and -G/-G groups, respectively. SVR rates were 82.1% or 49.3% in patients treated with peg-IFN plus ribavirin with or without telaprevir, respectively. IFNL4 ss469415590 variant and HCV viral loads or IFNL4 ss469415590 variant and early virological response were better predictors of SVR in patients treated with peg-IFN plus ribavirin with or without telaprevir, respectively.Conclusion. In the era of DAAs, measurement of IFNL4 ss469415590 variant could help the prediction of SVR in Japanese HCV genotype 1 infected individuals treated with IFN-including regimens.
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Sy, Aminata, Leanne McCabe, Emma Hudson, Azim M. Ansari, Vincent Pedergnana, Shang-Kuan Lin, S. Santana, et al. "Utility of a buccal swab point-of-care test for the IFNL4 genotype in the era of direct acting antivirals for hepatitis C virus." PLOS ONE 18, no. 1 (January 23, 2023): e0280551. http://dx.doi.org/10.1371/journal.pone.0280551.

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Background The CC genotype of the IFNL4 gene is known to be associated with increased Hepatitis C (HCV) cure rates with interferon-based therapy and may contribute to cure with direct acting antivirals. The Genedrive® IFNL4 is a CE marked Point of Care (PoC) molecular diagnostic test, designed for in vitro diagnostic use to provide rapid, real-time detection of IFNL4 genotype status for SNP rs12979860. Methods 120 Participants were consented to a substudy comparing IFNL4 genotyping results from a buccal swab analysed on the Genedrive® platform with results generated using the Affymetix UK Biobank array considered to be the gold standard. Results Buccal swabs were taken from 120 participants for PoC IFNL4 testing and a whole blood sample for genetic sequencing. Whole blood genotyping vs. buccal swab PoC testing identified 40 (33%), 65 (54%), and 15 (13%) had CC, CT and TT IFNL4 genotype respectively. The Buccal swab PoC identified 38 (32%) CC, 64 (53%) CT and 18 (15%) TT IFNL4 genotype respectively. The sensitivity and specificity of the buccal swab test to detect CC vs non-CC was 90% (95% CI 76–97%) and 98% (95% CI 91–100%) respectively. Conclusions The buccal swab test was better at correctly identifying non-CC genotypes than CC genotypes. The high specificity of the Genedrive® assay prevents CT/TT genotypes being mistaken for CC, and could avoid patients being identified as potentially ‘good responders’ to interferon-based therapy.
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Sorrentino, Leonardo, Valentina Silvestri, Giuseppe Oliveto, Mirko Scordio, Federica Frasca, Matteo Fracella, Camilla Bitossi, et al. "Distribution of Interferon Lambda 4 Single Nucleotide Polymorphism rs11322783 Genotypes in Patients with COVID-19." Microorganisms 10, no. 2 (February 4, 2022): 363. http://dx.doi.org/10.3390/microorganisms10020363.

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Type III interferons (IFN-III), also known as IFN-Lambda, have a pivotal role during SARS-CoV-2 infection. IFN-Lambda response among individuals is heterogeneous and its association with COVID-19 symptoms severity needs to be further clarified. We analyzed the genotype frequencies of IFNL4 single nucleotide polymorphism (SNP) rs11322783 in patients with COVID-19 (n = 128), in comparison with a validated data set of European healthy controls (n = 14152). The IFNL4 SNP was also analyzed according to the haematological and clinical parameters of patients with COVID-19. The distributions of IFNL4 genotypes among SARS-CoV-2 positive patients [TT/TT 41.4% (n = 53), TT/ΔG 47.7% (n = 61) and ΔG/ΔG 10.9% (n = 14)] and healthy controls were comparable. Different levels of white blood cells (p = 0.036) and neutrophils (p = 0.042) were found in the IFNL4 different genotypes in patients with COVID-19; the ΔG/ΔG genotype was more represented in the groups with low white blood cells and neutrophils. There were no differences in major inflammation parameters (C-reactive protein, D-dimer, Albumin, and Lactate-dehydrogenase (LDH)] and survival rate according to the IFNL4 genotypes. In conclusion, although patients with COVID-19 did not exhibit a different distribution of the IFNL4 SNP, the ΔG/ΔG genotype was associated with a lower count of immune cell populations. These findings need to be confirmed in larger groups of patients with COVID-19 and the role of IFNL4 SNP needs to be also investigated in other respiratory viral infections.
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SEVENSTER, MERLIJN. "DECIDABILITY OF INDEPENDENCE-FRIENDLY MODAL LOGIC." Review of Symbolic Logic 3, no. 3 (July 13, 2010): 415–41. http://dx.doi.org/10.1017/s1755020310000146.

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In this paper we consider an independence-friendly modal logic, IFML. It follows from results in the literature that qua expressive power, IFML is a fragment of second-order existential logic, $\Sigma _1^1$, that cannot be translated into first-order logic. It is also known that IFML lacks the tree structure property. We show that IFML has the ‘truncated structure property’, a weaker version of the tree structure property, and that its satisfiability problem is solvable in 2NEXP. This implies that this paper reveals a new decidable fragment of $\Sigma _1^1$. We also show that IFML becomes undecidable if we add the identity symbol to its vocabulary by means of a reduction from the tiling problem.
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Barlogie, Bart, Michel Attal, John Crowley, Frits van Rhee, Jackie Szymonifka, Philippe Moreau, Brian G. M. Durie, and Jean-Luc Harousseau. "Long-Term Follow-Up of Autotransplantation Trials for Multiple Myeloma: Update of Protocols Conducted by the Intergroupe Francophone du Myelome, Southwest Oncology Group, and University of Arkansas for Medical Sciences." Journal of Clinical Oncology 28, no. 7 (March 1, 2010): 1209–14. http://dx.doi.org/10.1200/jco.2009.25.6081.

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Purpose The purpose of this study was to update outcomes of autotransplantation trials for myeloma conducted by the Intergroupe Francophone du Myelome (IFM), the Southwest Oncology Group, and the University of Arkansas for Medical Sciences (Total Therapy [TT]). Methods IFM90 (N = 194), IFM04 (N = 402), IFM9902 (N = 692), IFM9904 (N = 197), S9321 (N = 817), TT1 (N = 231), TT2 (N = 668), and TT3 (N = 303) were updated, and results were compared with original reports. Results Superior survival with single transplantation versus standard therapy in IFM90 was confirmed (P = .004), and a trend in favor of tandem versus single transplantation was maintained in IFM94 (P = .08). S9321 data were validated, with comparable survival in single transplantation and standard treatment arms (P = .35). A survival benefit from thalidomide maintenance in IFM9902 was not confirmed (P = .39) but emerged for the thalidomide arm of TT2 (P = .04). On multivariate analysis, survival was superior in TT2, TT3, and IFM9902 (all P < .001); tandem transplantations were superior to both single transplantations and standard therapies (P < .001), as were tandem transplantations with added thalidomide versus trials without thalidomide (P < .001). Postrelapse survival (PRS) was superior when initial event-free survival (EFS) exceeded 1280 days and when tandem transplantations had been administered, whereas PRS was shorter when EFS lasted 803 days or less and when trials had included thalidomide and bortezomib. Conclusion These long-term follow-up data of transplantation trials provide a crucial framework of reference for outcome reporting of novel agent–based trials reportedly exhibiting remarkable short-term efficacy approaching high-dose therapy results.
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Huschka, Henriette, and Sabine Mihm. "Hepatic IFNL4 Gene Activation in Hepatocellular Carcinoma Patients with Regard to Etiology." International Journal of Molecular Sciences 22, no. 15 (July 21, 2021): 7803. http://dx.doi.org/10.3390/ijms22157803.

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Hepatocellular carcinoma (HCC) is a malignancy with a leading lethality. The etiology is quite diverse, ranging from viral infections to metabolic disorders or intoxications, and associates with specific somatic mutational patterns and specific host immunological phenotypes. Particularly, hepatitis C virus (HCV)-infected liver is featured by an activation of interferon (IFN)-stimulated genes (ISGs; IFN signature), which we suppose is driven by type III IFNL4. Taking advantage of the TCGA collection of HCC patients of various different etiologies, this study aimed at validating our previous findings on hepatic IFNL4 gene activation in HCV infection in an independent and larger cohort of patients with advanced liver disease. In a cohort of n = 377 cases, the entirety of the sequencing data was used to assess the IFNL genotypes, and the cases were stratified for etiology. The number of IFNL4 transcripts within nonmalignant and malignant tissues was found to be more abundant in patients with HCV or HCV/HBV infections when compared to other risk factors. Moreover, in patients with HCV infection as a risk factor, a close, positive relationship was found between ISG activation and the number of functional IFNL4 transcripts. Data on this independent TCGA sample support the concept of an IFNL4-dependent HCV-driven activation of hepatic ISGs. In addition to that, they add to the understanding of etiology-related host immunological phenotypes in HCC.
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Jenkins, Frank J., Tsion Z. Minas, Wei Tang, Tiffany H. Dorsey, and Stefan Ambs. "Abstract LB162: Human herpesvirus 8 infection is associated with prostate cancer among IFNL4-ΔG carriers." Cancer Research 82, no. 12_Supplement (June 15, 2022): LB162. http://dx.doi.org/10.1158/1538-7445.am2022-lb162.

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Abstract Background: Chronic inflammation as seen with chronic infections, has been proposed as a risk factor for prostate cancer. Numerous studies failed to identify a specific microbial agent associated with prostate cancer risk. We have previously reported that human herpesvirus 8 (HHV-8) is associated with increased prostate cancer risk in Tobago; a population that is 97% of African ancestry. This association was not found in several studies of US men, who were predominately of European American ancestry. It is unclear if the discrepancies between US and Tobago men are due to differences in HHV-8 seroprevalence rates or ancestry-related genetics. Previous studies have reported that the dinucleotide germline variant, rs368234815-ΔG, in the IFNL4 gene encoding interferon λ4 is more prevalent among individuals of African ancestry and impairs viral clearance. In this study, we investigated whether the association of HHV-8 with prostate cancer is IFNL4-ΔG-dependent. Methods: We investigated the association of HHV-8 seropositivity with prostate cancer in 728 IFNL4-ΔG-genotyped cases and 813 genotyped population-based control men from the NCI-Maryland Prostate Cancer Case-Control study. Associations between HHV-8 and prostate cancer were assessed in multivariable unconditional logistic regression models. We calculated adjusted odds ratios (OR) and stratified the analysis into men harboring the IFNL4-ΔG-variant and non-carriers (ΔG/ΔG or ΔG/TT vs. TT/TT). Results: HHV-8 seropositivity was higher in cases than controls (OR 1.76; 95%CI: 1.20 - 2.59). The association of HHV-8 seropositivity with prostate cancer was restricted to carriers of the ΔG allele (OR 2.19: 95%CI: 1.38 - 3.48). HHV-8 seropositivity did not associate with prostate cancer among TT/TT genotype carriers (OR 1.03: 95%CI: 0.51 - 2.11). Further stratification by race/ethnicity showed that HHV-8 is associated with prostate cancer exclusively among carriers of the ΔG allele in both European American (OR 2.59; 95%CI: 1.20 - 5.56) and African American men (OR 1.96; 95%CI: 1.08 - 3.56). Conclusions: HHV-8 seropositivity is associated with increased odds of prostate cancer in men harboring the IFNL4 rs368234815-ΔG variant. Impact: The study establishes IFNL4-ΔG as a candidate prostate cancer risk factor in men with an HHV-8 infection. This gene-environment association of IFNL4-ΔG with prostate cancer should be further evaluated using prospective study designs. Citation Format: Frank J. Jenkins, Tsion Z. Minas, Wei Tang, Tiffany H. Dorsey, Stefan Ambs. Human herpesvirus 8 infection is associated with prostate cancer among IFNL4-ΔG carriers [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr LB162.
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Gadalla, Shahinaz M., Tao Wang, Olusegun Onabajo, Youjin Wang, Michael D. Haagenson, Jennifer A. Sees, Stephen R. Spellman, Hormuzd A. Katki, Stephanie J. Lee, and Ludmila Prokunina-Olsson. "Donor IFNL4 Genotype Is Associated with Transplant-Related Mortality after Unrelated Donor Myeloablative Hematopoietic Cell Transplantation in Patients with Acute Leukemia." Blood 132, Supplement 1 (November 29, 2018): 968. http://dx.doi.org/10.1182/blood-2018-99-111391.

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Abstract Introduction. Interferon Lambda 4 gene (IFNL4) encodes IFN-λ4 protein, a new member of the type-III interferon family. IFNL4 genotype (rs368234815-dG allele), defines the genetic ability to produce IFN-λ4 and has been associated with reduced clearance of hepatitis C virus (HCV) infection. Given antiviral activity and immune modulation properties of IFN-λ4, we hypothesized that IFNL4 genotype of recipient and/or donor may modulate post-transplant survival outcomes, possibly through control of viral infections, and/or alloreactivity. Methods. From the Center for International Blood and Marrow Transplant Research (CIBMTR) database, we randomly selected 627 patients who received unrelated hematopoietic cell transplantation (HCT) for acute myeloid leukemia (AML, N=449) or acute lymphocytic leukemia (ALL, N=178). The patients had to match the following criteria: 1) HCT between 2004 and 2012, 2) available pre-HCT blood sample for the donor and recipient, 3) 8/8 HLA matching, and 3) myeloablative conditioning. IFNL4 genotyping was completed for 619 donors and 522 recipients using a custom-designed TaqMan assay for rs368234815. Multivariable Cox proportional hazard models were used for statistical analyses. Follow-up ended in November 2017. Results. Median age at HCT was 40 years (range=<1-68). Most patients (66%, N=411) were in first complete remission, had a Karnofsky Performance Score (KPS) between 90-100% (70%, N=436), and received peripheral blood stem cell grafts (70%, N=439). The median post-HCT follow-up was 68 months (range=5-122). Donor IFNL4 genotype was associated with risk of transplant-related mortality (TRM); with 5 years probabilities=19%, 27%, and 30% for donor TT/TT (n=286), TT/dG (n=267), and dG/dG (n=64) genotypes, respectively, p=0.02. The results remained significant in multivariable analysis (p=0.002); compared with patients receiving HCT from donors with TT/TT genotype, with the HR=1.59 (95% CI=1.13-2.23, p=0.007) for TT/dG donors and HR=1.95 (95% CI=1.18-3.23, p=0.009) for dG/dG donors. The data suggested that donor IFNL4 genotype may also predict risk of disease-free survival (DFS; HR=1.43, 95% CI=1.02-2.00, p=0.03), and overall survival (OS; HR=1.40 (95% CI=0.98-1.99, p=0.06) for donor dG/dG genotype (Table1). No association between recipient genotype and any survival outcome was observed (p>0.05 for OS, DFS, and TRM) Conclusions. Donor IFNL4 genotype is associated with risk of transplant-related mortality in patients with acute leukemia. The data suggest that avoiding donors with dG/dG genotype will improve HCT outcomes without limiting the potential donor pool. A validation study is needed; if confirmed, IFNL4 genotype may provide an added value to donor selection criteria. Disclosures Lee: Onyx: Research Funding; Kadmon: Research Funding; Amgen: Consultancy, Research Funding; Mallinckrodt: Honoraria; Incyte: Consultancy; Pfizer: Consultancy; Takeda: Research Funding.
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Wakil, Karzan, and Dayang N. A. Jawawi. "Extensibility Interaction Flow Modeling Language Metamodels to Develop New Web Application Concerns." Kurdistan Journal of Applied Research 2, no. 3 (August 27, 2017): 172–77. http://dx.doi.org/10.24017/science.2017.3.23.

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Web engineering is a systematic approach to develop web applications, and numerous web engineering methods have been proposed. These methods were extended through defining new models by using different mechanisms to capture the web application concepts. Due to the complexity rising of web applications, the web engineering methods cannot provide web solutions anymore. Even though Interaction Flow Modeling Language (IFML) is recently proposed as a new method for developing web applications, it has limitations. Therefore these methods need to be improved. In this paper, we present the ability of IFML extensibility to support new concerns from web applications. Moreover, we extend IFML through UML mechanisms to support new concerns from the context to the user interface. The new IFML solves the lack of context web application through defining a new model and becomes a new direction to develop concerns modern web applications.
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Dissertations / Theses on the topic "IFML4"

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MARCEDDU, GIUSEPPE. "Bioinformatics e Biostatistics applied to research in pediatric genetic disease. Clinical evidence in IFNλ4 polymorphisms associated with HCV infection in patients with beta thalassemia and WGCNA analysis weighted for IFNλ4 genotype rs12979860 to detect RPL9P18 as hub in HCV infected cell." Doctoral thesis, Università degli Studi di Cagliari, 2015. http://hdl.handle.net/11584/266612.

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Genome-wide association studies have identified host genetic variation to be critical for spontaneous clearance and treatment response in patients infected with hepatitis C virus (HCV). We demonstrated the same in patients with thalassemia major infected by genotype 1b of HCV. In the present first part study we retrospectively analyzed 368 anti-HCV positive patients with beta-thalassemia in two Italian major thalassemic centers (Cagliari and Turin). The strongest IFNλ4 SNP found associated with HCV was rs12979860 where C/C genotype was related to response to the interferon treatment and, above all, to spontaneous clearance of the virus. However, the positive predictive power was stronger for viral persistence than spontaneous clearance indeed TT allele was more predictive than CC. Another polymorphism rs4803221 was analyzed because had independent effects respect to rs12979860. The haplotype tagged by SNP rs12979860 and rs4803221 significantly could improve the viral clearance prediction in infected patients. Neither necrotic-inflammation or bilirubin values in the chronic phase of the hepatitis C were related to IFNλ4 polymorphisms. No relation among IFNλ4 polymorphisms and fibrosis stage directly shown by the liver biopsy was found. Second part of our study was to identify hub genes associated in pathways closely related to IFNλ4 variants in HCV response. We used gene expression profile data of GSE54648, downloaded from Gene Expression Omnibus (GEO). We focused our attention on expression genes differential between rs12979860 unfavorable TT genotype and favorable CC genotype, using weighted gene expression network analysis (WGCNA - R package). Significant modules were selected using the clustering analysis. At the final the best significant module was “black” module. Its pathways were involved in translation mechanisms such as translation termination, translation elongation, nuclear-transcribed mRNA catabolic process, cellular protein complex disassembly, therefore biological mechanisms that occur inside ribosome. We discovered RPL9P18 pseudogene as a hub potentially related in inhibition of spontaneous clearance and furthermore likely involved in drug treatment inhibition. Our result suggests an active role for ribosome pseudogene in innate antiviral response probably during ISG (IFN-stimulated genes) translation. Moreover, through co-expression analysis we demonstrate a new possible role of IFNλ4 genotype in HCV infection, associate with expression of ribosomal pathways.
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Syrový, Jiří. "Vývoj a implementace webové aplikace s podporou notace IFML." Master's thesis, 2015. http://www.nusl.cz/ntk/nusl-189543.

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Syrový, J. Development and implementation of web applications with the support of IFML notation. Diploma thesis. Brno: Mendel University in Brno, 2015. This diploma thesis deals with the problems of development and implementation of web applications with the support of IFML notation. Processes in the sales department of middle-sized company which are focused on the electronic auctions are modelled through the use of UML 2.0 notation and BPMN 2.0 using a CASE software tool called Enterprise Architect. Then the complete process of development of web applications is made with the support of the product's life cycle using the modeling language IFML and a CASE software tool called WebRatio. The implementation of web applications is made using ASP.NET technology and Microsoft SQL Server.
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Matulík, Ondřej. "Realizace webové aplikace sportovního klubu s podporou CASE nástroje WebRatio a jazyka IFML." Master's thesis, 2016. http://www.nusl.cz/ntk/nusl-251294.

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Implementation of web application for sport club with the support of CASE tool WebRatio and IFML notation. Diploma thesis. Brno: Mendel University in Brno, 2015. This diploma thesis deals with implementation of web application for sport club with the support of CASE tool WebRatio and IFML notation. The thesis describes software development method-ologies with a main focus on web applications and IFML notation. The practical part of this thesis deals with the implementation of a web application based on analysis of the current state of the problem domain and defined business requirements. Development process of entire application was conducted in accordance with the IFML notation. For the analysis and system modelling were used diagrams and models of UML2 and IFML languages. Models and diagrams were made by CASE tool WebRatio and Enterprise Architect. The application was implemented using ASP.NET MVC technology, Mi-crosoft SQL Server database tool and C# language.
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Záboj, Martin. "Návrh a implementace inovativních řešení podnikového informačního systému." Master's thesis, 2017. http://www.nusl.cz/ntk/nusl-431967.

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Záboj, M. Design and implementation of innovative enterprise information system solutions. Brno: Mendel University, 2017. This diploma thesis deals with the analysis of real processes in the company, which focuses on the development of web applications and systems. Processes are modeled using the BPMN 2.0 notation and their simulations are performed. Based on the analysis, process innovations are designed.Complete process of developing a web application is performedwith IFML support. Implementation of the applica-tion is completed in the Nette framework.
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Huschka, Henriette. "Genetische Polymorphismen in Typ-III-Interferon-Genen und deren prognostische Signifikanz für das hepatozelluläre Karzinom und das duktale Pankreasadenokarzinom." Doctoral thesis, 2021. http://hdl.handle.net/21.11130/00-1735-0000-0005-1598-8.

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Books on the topic "IFML4"

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Wazlawick, Raul Sidnei. Object-Oriented Analysis and Design for Information Systems: Modeling with UML, OCL, and IFML. Elsevier Science & Technology Books, 2014.

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Object-Oriented Analysis and Design for Information Systems: Modeling with UML, OCL, and IFML. Elsevier Science & Technology Books, 2014.

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Interaction Flow Modeling Language: Model-Driven UI Engineering of Web and Mobile Apps with IFML. Elsevier Science & Technology Books, 2014.

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Brambilla, Marco, and Piero Fraternali. Interaction Flow Modeling Language: Model-Driven UI Engineering of Web and Mobile Apps with IFML. Elsevier Science & Technology Books, 2014.

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Book chapters on the topic "IFML4"

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Rodriguez-Echeverria, Roberto, Javier Luis Cánovas Izquierdo, and Jordi Cabot. "Towards a UML and IFML Mapping to GraphQL." In Current Trends in Web Engineering, 149–55. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-74433-9_13.

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Fatima, Iffat, Muhammad Waseem Anwar, Farooque Azam, Bilal Maqbool, and Hanny Tufail. "Extending Interaction Flow Modeling Language (IFML) for Android User Interface Components." In Communications in Computer and Information Science, 76–89. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-30275-7_7.

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Laaz, Naziha, and Samir Mbarki. "Combining Ontologies and IFML Models Regarding the GUIs of Rich Internet Applications." In Artificial Intelligence: Methodology, Systems, and Applications, 226–36. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-44748-3_22.

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Acerbis, Roberto, Aldo Bongio, Marco Brambilla, and Stefano Butti. "Model-Driven Development Based on OMG’s IFML with WebRatio Web and Mobile Platform." In Engineering the Web in the Big Data Era, 605–8. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-19890-3_39.

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Wakil, Karzan, Dayang N. A. Jawawi, and Naziha Laaz. "Role of Interaction Flow Modeling Language (IFML) in the Development of Ubiquitous Web Applications (UWAs)." In Advances in Intelligent Systems and Computing, 390–401. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-36674-2_40.

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Brambilla, Marco, Andrea Mauri, and Eric Umuhoza. "Extending the Interaction Flow Modeling Language (IFML) for Model Driven Development of Mobile Applications Front End." In Mobile Web Information Systems, 176–91. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-10359-4_15.

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Riaz, Muhammad Talha, Farooque Azam, Nazish Yousaf, Muhammad Waseem Anwar, and Adil Aziz. "An Approach of Usability Testing for Web User Interface Through Interaction Flow Modeling Language (IFML) Models." In Advances in Internet, Data and Web Technologies, 552–63. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-39746-3_56.

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Brambilla, Marco, and Piero Fraternali. "IFML extensions." In Interaction Flow Modeling Language, 137–66. Elsevier, 2015. http://dx.doi.org/10.1016/b978-0-12-800108-0.00007-2.

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Brambilla, Marco, and Piero Fraternali. "IFML by examples." In Interaction Flow Modeling Language, 233–77. Elsevier, 2015. http://dx.doi.org/10.1016/b978-0-12-800108-0.00009-6.

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"IFML notation summary." In Interaction Flow Modeling Language, 381–87. Elsevier, 2015. http://dx.doi.org/10.1016/b978-0-12-800108-0.15001-5.

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Conference papers on the topic "IFML4"

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Queiroz, Randerson, Anna Beatriz Marques, Adriana Lopes, Edson Oliveira, and Tayana Conte. "Evaluating Usability of IFML Models." In IHC 2018: 17th Brazilian Symposium on Human Factors in Computing Systems. New York, NY, USA: ACM, 2018. http://dx.doi.org/10.1145/3274192.3274213.

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Rodriguez-Echeverria, Roberto, José M. Conejero, Juan C. Preciado, and Fernando Sanchez-Figueroa. "AutoCRUD - Automating IFML Specification of CRUD Operations." In International Workshop on Avanced practices in Model-Driven Web Engineering. SCITEPRESS - Science and and Technology Publications, 2016. http://dx.doi.org/10.5220/0005923003070314.

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Frajták, Karel, Miroslav Bureš, and Ivan Jelínek. "Transformation of IFML schemas to automated tests." In the 2015 Conference. New York, New York, USA: ACM Press, 2015. http://dx.doi.org/10.1145/2811411.2811556.

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Huang, An, Minxue Pan, Tian Zhang, and Xuandong Li. "Static extraction of IFML models for Android apps." In MODELS '18: ACM/IEEE 21th International Conference on Model Driven Engineering Languages and Systems. New York, NY, USA: ACM, 2018. http://dx.doi.org/10.1145/3270112.3278185.

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Gotti, Sara, and Samir Mbarki. "Toward IFVM Virtual Machine: A Model Driven IFML Interpretation." In 11th International Conference on Software Engineering and Applications. SCITEPRESS - Science and Technology Publications, 2016. http://dx.doi.org/10.5220/0005986102200225.

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Queiroz, Randerson, Anna Beatriz Marques, and Tayana Conte. "Using IFML for user interface modeling: an empirical study (S)." In The 30th International Conference on Software Engineering and Knowledge Engineering. KSI Research Inc. and Knowledge Systems Institute Graduate School, 2018. http://dx.doi.org/10.18293/seke2018-103.

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Hamdani, Maryum, Wasi Haider Butt, Muhammad Waseem Anwar, and Farooque Azam. "A Systematic Literature Review on Interaction Flow Modeling Language (IFML)." In the 2018 2nd International Conference. New York, New York, USA: ACM Press, 2018. http://dx.doi.org/10.1145/3180374.3181333.

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Laaz, Naziha, and Samir Mbarki. "Integrating IFML models and owl ontologies to derive UIs web-Apps." In 2016 International Conference on Information Technology for Organizations Development (IT4OD). IEEE, 2016. http://dx.doi.org/10.1109/it4od.2016.7479284.

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Piotopoulos, Stavros, and Evangelos Sakkopoulos. "Transforming procedures to web applications using IFML: The new Greek Citizenship Test." In 2021 12th International Conference on Information, Intelligence, Systems & Applications (IISA). IEEE, 2021. http://dx.doi.org/10.1109/iisa52424.2021.9555545.

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Laaz, Naziha, and Samir Mbarki. "A model-driven approach for generating RIA interfaces using IFML and ontologies." In 2016 4th IEEE International Colloquium on Information Science and Technology (CIST). IEEE, 2016. http://dx.doi.org/10.1109/cist.2016.7805005.

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