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Journal articles on the topic 'Ig G anti body'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Perales-Torres, Adriana L., Lucia M. Perez-Navarro, Esperanza M. Garcia-Oropesa, et al. "Influence of adiposity and sex on SARS-CoV-2 antibody response in vaccinated university students: A cross-sectional ESFUERSO study." PLOS Global Public Health 4, no. 7 (2024): e0002686. http://dx.doi.org/10.1371/journal.pgph.0002686.

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Prior studies have identified various determinants of differential immune responses to COVID-19. This study focused on the Ig-G anti-RBD marker, analyzing its potential correlations with sex, vaccine type, body fat percentage, metabolic risk, perceived stress, and previous COVID-19 exposure. In this study, data (available in S1 Data) were obtained from 108 participants from the ESFUERSO cohort, who completed questionnaires detailing their COVID-19 experiences and stress levels assessed through the SISCO scale. IgG anti-RBD concentrations were quantified using an ELISA assay developed by UNAM.

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Dingemans, Anne-Marie, Nico van Walree, Franz Schramel, et al. "High Protein Oral Nutritional Supplements Enable the Majority of Cancer Patients to Meet Protein Intake Recommendations during Systemic Anti-Cancer Treatment: A Randomised Controlled Parallel-Group Study." Nutrients 15, no. 24 (2023): 5030. http://dx.doi.org/10.3390/nu15245030.

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ESPEN guidelines recommend a minimum protein intake of 1.0 g/kg body weight (BW) per day to maintain or restore lean body mass in patients with cancer. During anti-cancer treatment, optimal protein intake is difficult to achieve. We investigated whether a high-protein, low-volume oral nutritional supplement (ONS) supports patients in meeting recommendations. A multi-centre, randomised, controlled, open-label, parallel-group study was carried out in nine hospitals (five countries) between January 2019 and July 2021 in colorectal and lung cancer patients undergoing first-line systemic treatment

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Kaya, Mehmet Nur, Özlem Kılıç, Muhammet Canbaş, Merve Sungur Özgünen, Ezgi Çimen Güneş, and Sedat Yılmaz. "Role of intravenous immunoglobulins in the management of systemic lupus erythematosus: a single-centre experience." Lupus Science & Medicine 11, no. 2 (2024): e001402. http://dx.doi.org/10.1136/lupus-2024-001402.

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ObjectivesSystemic lupus erythematosus (SLE) is a chronic autoimmune disease of unknown aetiology that can affect almost any organ in the body. Although there are no specific guidelines for the use of intravenous immunoglobulin (IG) in the treatment of patients with SLE, it is thought to be an effective treatment. Our study aimed to evaluate the effectiveness and safety of intravenous IG and to describe the possible profile of patients with SLE who are candidates for intravenous IG treatment.MethodsThis study was designed to retrospectively analyse patients with SLE treated with 2 g/kg/month o

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Solang, Margaretha, Masra Latjompoh, Said Butungale, and Aryati Abdul. "Study of Corn Milk (Zea mays saccarata L) Glicemic Index (IG) as Anti-Diabetic Foods." E3S Web of Conferences 400 (2023): 02010. http://dx.doi.org/10.1051/e3sconf/202340002010.

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Plants that have a low glycemic index, such as corn, can be an alternative food consumed by the public to prevent blood sugar levels from rising. Corn is not only low in the glycemic index but also rich in dietary fiber, fe, and beta-carotene (provitamin A). This study aims to examine the carbohydrate content and glycemic index (GI) of sweet corn milk (Zea mays saccarata L). This research uses descriptive quantitative analysis to describe the results of corn milk index values. This research was conducted in the Laboratory of Biochemistry, Department of Biology, Universitas Negeri Gorontalo, in

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Liang, ZhenHong, XiaoHong Liu, and ShuMei Gong. "EVALUATION OF ANTI-HYPERGLYCEMIC ACTIVITIES OF PHLORIDZIN IN DIABETIC MICE." African Journal of Traditional, Complementary and Alternative Medicines 13, no. 3 (2016): 209–18. http://dx.doi.org/10.21010/ajtcam.v13i3.25.

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Background: The aim of the study was to investigate the hypoglycemic effects of Phloridzin. Methods and Materials: High fat diet induced diabetic KKAy mice were administered with phloridzin at an oral dose (60 mg/kg/day, ig.) for 10 weeks. A range of parameters, including blood glucose and lipid, serum insulin, glucose tolerance, were tested to evaluate its anti-hyperglycemic effects. Results: Phloridzin decreased water-intake, body weight, FBG, FINS, HOME-IR, Serum leptin, and CRP levels, increased serum adiponectin level in diabetic mice. Phloridzin also improve

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Rajeev, Kumar, Astik S.K., Bhaskar Subham, Kumar Narendra, and Kumar Sinha Ajay. "A Hospital-Based Study to Assess the Association between Blood PLT and RBC Related Indices and Disease Activity in Patients with Rheumatoid Arthritis." International Journal of Pharmaceutical and Clinical Research 15, no. 1 (2023): 1255–63. https://doi.org/10.5281/zenodo.13163365.

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<strong>Aim: </strong>This study aimed to evaluate the association of blood PLT and RBC related parameters with the disease activity in rheumatoid arthritis (RA) patients. <strong>Methods: </strong>This study included 200 RA patients who were admitted to the Department of General medicine at Nalanda Medical College and Hospital, Patna, Bihar, India for the period of one year. <strong>Results: </strong>There were no differences in age and gender distribution, body mass index (BMI) and WBC between the two groups. Besides, CRP, ESR, RF and anti-CCP in RA patients were sig

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Uchida, Akiko, Kenji Tanimura, Keisuke Shirai, et al. "Discrepancies in the Diagnosis of Congenital Toxoplasma gondii Infection Between B1 Gene Semi-Nested Polymerase Chain Reaction and Serological Analyses." Microorganisms 13, no. 3 (2025): 601. https://doi.org/10.3390/microorganisms13030601.

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Congenital Toxoplasma gondii (T. gondii) infection, which can be caused by a primary T. gondii infection during pregnancy, results in severe neurological sequelae in affected children. We have been conducting a prospective cohort study since January 2019 on pregnant women who were suspected of having primary T. gondii infection based on serological tests. In this study, congenital infection was diagnosed using semi-nested polymerase chain reaction (PCR) to detect the B1 gene in the body fluids of newborns. Up until December 2023, forty-one newborns born to mothers suspected of having primary T

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Conrad, Matthew B., Alex Trauner, Jason Hull, Michelle Hawkins, Brian Robley, and Amanda N. Bradbery. "PSIII-5 Confirmation of Passive Transfer of Anti-Endotoxin Igy in Neonatal Foals." Journal of Animal Science 101, Supplement_3 (2023): 386. http://dx.doi.org/10.1093/jas/skad281.457.

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Abstract Passive immune transfer in a newborn foal is highly dependent upon the quality and concentration of immunoglobulins (Ig) in maternal colostrum, primarily IgG. Anti-endotoxin IgY derived from chicken egg yolks has been used in calves to reduce morbidity and mortality. Its use may provide additional pathogen-specific immune protection to neonatal foals, but passive transfer has not been confirmed. Therefore, the objective of this study was to quantify passive IgY transfer in neonatal foals given an egg-derived anti-endotoxin IgY supplement (Camas, Inc.) and identify effects on passive i

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Nussey, Daniel H., Kathryn A. Watt, Abigail Clark, et al. "Multivariate immune defences and fitness in the wild: complex but ecologically important associations among plasma antibodies, health and survival." Proceedings of the Royal Society B: Biological Sciences 281, no. 1779 (2014): 20132931. http://dx.doi.org/10.1098/rspb.2013.2931.

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Despite our rapidly advancing mechanistic understanding of vertebrate immunity under controlled laboratory conditions, the links between immunity, infection and fitness under natural conditions remain poorly understood. Antibodies are central to acquired immune responses, and antibody levels circulating in vivo reflect a composite of constitutive and induced functional variants of diverse specificities (e.g. binding antigens from prevalent parasites, self tissues or novel non-self sources). Here, we measured plasma concentrations of 11 different antibody types in adult females from an unmanage

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Scott, Fiona, Christian Wichmann, Ingrid Burvenich, et al. "324 Preclinical evaluation of anti-VISTA antibody CI-8993 in a syngeneic huVISTA-KI model." Journal for ImmunoTherapy of Cancer 9, Suppl 2 (2021): A349. http://dx.doi.org/10.1136/jitc-2021-sitc2021.324.

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BackgroundVISTA (V-domain Ig suppressor of T-cell activation) inhibits anti-tumour immune responses. The Investigational product CI-8993 is a fully human IgG1k monoclonal antibody that binds specifically to this immune checkpoint molecule. Phase I safety has been established in prior trials in patients with advanced cancer (NCT02671955). To assist determining the pharmacokinetics and biodistribution of CI-8993 in patients we aimed to develop a Zirconium-89 (89Zr)-labelled CI-8993 for PET imaging and quantitation, and validate in preclinical models prior to a planned human trial.MethodsConjugat

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Galmiche, Marie, Nicolas Lucas, Pierre Déchelotte, et al. "Plasma Peptide Concentrations and Peptide-Reactive Immunoglobulins in Patients with Eating Disorders at Inclusion in the French EDILS Cohort (Eating Disorders Inventory and Longitudinal Survey)." Nutrients 12, no. 2 (2020): 522. http://dx.doi.org/10.3390/nu12020522.

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Eating disorders (EDs) are increasingly frequent. Their pathophysiology involves disturbance of peptide signaling and the microbiota–gut–brain axis. This study analyzed peptides and corresponding immunoglobulin (Ig) concentrations in groups of ED. In 120 patients with restrictive (R), bulimic (B), and compulsive (C) ED, the plasma concentrations of leptin, glucagon-like peptide-1 (GLP-1), peptide YY (PYY), and insulin were analyzed by Milliplex and those of acyl ghrelin (AG), des-acyl ghrelin (DAG), and α-melanocyte-stimulating hormone (α-MSH) by ELISA kits. Immunoglobulin G (in response to an

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Rutigliano, Vincenzo, Enzo Ierardi, Ruggiero Francavilla, et al. "Helicobacter pylori and Nonulcer Dyspepsia in Childhood: Clinical Pattern, Diagnostic Techniques, and Bacterial Strains." Journal of Pediatric Gastroenterology and Nutrition 28, no. 3 (1999): 296–300. http://dx.doi.org/10.1002/j.1536-4801.1999.tb02066.x.

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ABSTRACTBackground:This is a report of the results of a multicenter study performed in children with dyspepsia from five pediatric centers in Puglia, a region in southern Italy. In the study, clinical features of Helicobacter pylori infection, the reliability of diagnostic techniques, and the involvement of bacterial strains were examined.Methods:Fifty‐three outpatients with dyspepsia enrolled in our study and compiled a diary recording clinical symptoms in patients before they underwent the following diagnostic techniques: endoscopy, biopsy for histologic analysis, rapid urease test, 13C urea

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Srinivas, G., D.V. Ramanjaneyulu, E. Muralinath, et al. "An Essential Parameters of Parvo Virus Include Patho Physiology, Histo Pathology, Diagnosis, Differential Diagnosis, Treatment and Prognosis." Journal of Research and Reviews in Nursing Science and Education 2, no. 2 (2025): 11–17. https://doi.org/10.5281/zenodo.15541791.

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<em>One virus that only affects people is parvovirus B19. The fifth illness, also known as erythema infectious or slapped cheek syndrome, is known to be caused by it. It primarily affects young children, though it can sometimes affect adults. In addition, it may result in Poly arthropathy, popular-purpuric gloves and socks syndrome (PPGSS) in young people, certain anemias, hydrops fetalis, particularly in pregnant women, and an aplastic crisis. Viral transmission occurs through both respiratory secretions and blood products. The virus can infect a pregnant woman and then infect her unborn chil

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Gorbacheva, I. A., I. N. Antonova, Yu A. Sycheva, V. V. Ivanov, Yu R. Kulikova, and P. S. Shabak-Spassky. "The involvement of chronic persistent viral infection to various diseases of the oral cavity." Parodontologiya 25, no. 4 (2020): 301–7. http://dx.doi.org/10.33925/1683-3759-2020-25-4-301-307.

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Relevance. According to the literature all over the world, there is a tendency to reduce immunological reactivity in humans, this is facilitated by the presence of chronic persistent herpes viral infection. Herpes infection has systemic immunosuppressive effects of the infection on the human body, and also highlighted the role of the virus in a slow occurrence of combined pathology of internal organs and infectious and inflammatory diseases of the oral tissues and periodontium. High interest of specialists to this problem сaused by the necessity of new methods of complex treatment polymorbidit

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Bae, Jooeun, Shuichi Kitayama, Zach Herbert, et al. "Development of B-cell maturation antigen (BCMA)-specific CD8⁺ cytotoxic T lymphocytes using induced pluripotent stem cell technology for multiple myeloma." Journal of Clinical Oncology 40, no. 16_suppl (2022): 2542. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.2542.

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2542 Background: A strategy for reversal of T cell exhaustion is reprograming of antigen-specific CTL to early lineage memory T cells with selective anti-tumor activities. To accomplish this goal, we epigenetically reprogrammed BCMA-specific CD8+ CTL to a pluripotent state through key defined transcription factors, established “induced Pluripotent Stem Cells (iPSC)” exhibiting transcriptional and epigenetic features, re-differentiated them back into antigen-specific CTL and evaluated their properties and functional activities against multiple myeloma (MM). Methods: Functionally activeIFN-g pro

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Bae, Jooeun, Shuichi Kitayama, Zach Herbert, et al. "Development of B-cell maturation antigen (BCMA)-specific CD8⁺ cytotoxic T lymphocytes using induced pluripotent stem cell technology for multiple myeloma." Journal of Clinical Oncology 40, no. 16_suppl (2022): 2542. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.2542.

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2542 Background: A strategy for reversal of T cell exhaustion is reprograming of antigen-specific CTL to early lineage memory T cells with selective anti-tumor activities. To accomplish this goal, we epigenetically reprogrammed BCMA-specific CD8+ CTL to a pluripotent state through key defined transcription factors, established “induced Pluripotent Stem Cells (iPSC)” exhibiting transcriptional and epigenetic features, re-differentiated them back into antigen-specific CTL and evaluated their properties and functional activities against multiple myeloma (MM). Methods: Functionally activeIFN-g pro

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BILAL, R. M., F. HASSAN, M. SAEED, et al. "Prospects of yeast based feed additives in poultry nutrition: Potential effects and applications." Indian Journal of Animal Sciences 90, no. 4 (2020): 495–505. http://dx.doi.org/10.56093/ijans.v90i4.104177.

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Yeast and its derivatives are extensively utilized as feed additives in poultry industry owing to their desirable health and growth promoting effects. Exhaustive number of studies had reported positive effects of yeast based additives on growth, meat quality, immunity, antioxidant status, and gastrointestinal functions in poultry birds. Owing to their prebiotic/probiotic properties, they also play significant role in gut development and modulation of gut microbiome by favouring beneficial microbes while reducing colonization of pathogenic microbes by competitive exclusion. They also possess ef

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A. Muhsin, Mohammed, Mohammed Sh. Jebur, and Basim M. Hussan. "Detection of Epsteinâ€“Barr virus and Cytomegalovirus in Iraqi Acute Lymphoblastic Leukemia patients." AL-QADISIYAH MEDICAL JOURNAL 10, no. 18 (2017): 201–8. http://dx.doi.org/10.28922/qmj.2014.10.18.201-208.

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Objective : determination the percent of infection of EBV and CMV infections in Iraqi patient infected with ALL .Methods : the study have concentrated to determine the rate of EBV and CMV infections by detecting EBV and CMV antibodies in both the IgM and IgG classes of immunoglobulins by ELISA method and Indirect Immunofluorescence Test ( IIFT) as well as chromogenic in situ hybridization (CISH) for detecting Epstein-Barr virus (EBV) EBER RNA and CMV DNA . Results : from total 50 ALL patients were involved in this study , 50% were having viral infection (22% patients infected with EBV and 28%

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Sydorchuk, L., O. Gavrilyuk, S. Deineka, et al. "Immunosupressive activity of opportunist pathogens of the infectious-inflammatory process in the urinary tract of men with calculous pyelonephritis." Bukovinian Medical Herald 25, no. 3 (99) (2021): 102–9. http://dx.doi.org/10.24061/2413-0737.xxv.3.99.2021.16.

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Objective - identification of pathogens of the infectious-inflammatory process of the urinary tract in men with calculous pyelonephritis, antilysozyme, anticomplementary, anti-immunoglobulin activity and inhibitory effect on the phagocytic activity of peripheral blood neutrophils.Material and methods. 34 strains of opportunistic taxa were isolated and identified by bacteriological method from 30 sick men aged 31 to 65 years (mean age 48.8 ± 4.27 years). These bacteria have antilysozyme, anti-complementary and anti-immunoglobulin activity, as well as the suppressive effect of supernatants of cu

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Sotoodeh Jahromi, Abdolreza, Abbas Ahmadi-vasmehjani, Hassan Zabetian, et al. "Sero-Epidemiological Study of Hepatitis E Virus among Thalassemia as High Risk Patients: A Cross-Sectional Survey in Jahrom, Southern, Iran." Global Journal of Health Science 8, no. 9 (2016): 245. http://dx.doi.org/10.5539/gjhs.v8n9p245.

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<p>Hepatitis E virus (HEV) could be cause of viral hepatitis in the developing countries and cause severe epidemics. According to other studies, blood transfusion as a probable route of HEV infection has been suggested. An infection with hepatitis agents such as HEV causes active liver failure in multi-transfusion patients in particular thalassemia. The purpose of this study determines the seropositivity of anti-HEV antibodies in thalassemia individuals in Jahrom. In a cross-sectional study, sera from 110 thalassemia were collected between 2013 and 2014. Enzyme-linked immunosorbent assay

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Simpson, L., I. McNiece, M. Newberg, et al. "Detection and characterization of a B cell stimulatory factor (BSF-TC) derived from a bone marrow stromal cell line." Journal of Immunology 142, no. 11 (1989): 3894–900. http://dx.doi.org/10.4049/jimmunol.142.11.3894.

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Abstract Stromal cell lines derived from murine bone marrow support the growth of immature pre-B cells and produce cytokines that affect the growth and differentiation of other hematopoietic precursors. Conditioned medium (CM) from one such line (TC-1) stimulated marked proliferation of B cells previously activated by anti-Ig (anti-Ig blasts). Proliferation of anti-Ig blasts was not induced by purified cytokines known to be produced by TC-1 (CSF-1, GM-CSF, or G-CSF) or by IL-1, IL-2, IL-3, IL-4, IL-5, or IL-6. Furthermore, IL-2, IL-4, and IL-5, alone or in combination, failed to support prolif

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S, Donatila Mano, Yohanes Firmansyah, Hendsun Hendsun, Edwin Destra, and Alexander Halim Santoso. "Hubungan Jarak Waktu dan Jumlah Vaksin dengan Hasil Reaktif Ig-G SARS-Cov-2 (Studi Kasus Populasi Remaja SMA Kalam Kudus II Jakarta)." Malahayati Nursing Journal 5, no. 8 (2023): 2338–50. http://dx.doi.org/10.33024/mnj.v5i8.10594.

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ABSTRACT Vaccination against SARS-CoV-2 is essential in enhancing the body's defense against SARS-CoV-2 infection by increasing the level of Ig-G antibodies against SARS-CoV-2. Determining the relationship between the number of vaccines and the vaccination interval plays a role in the level of Ig-G antibodies against SARS-CoV-2 in the body to prevent primary infection from SARS-CoV-2. The assessment of cause-effect relationships is conducted through a cross-sectional study involving 76 subjects who met the inclusion criteria. The analysis performed includes descriptive analysis and analytical

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Marcinnò, Andrea, Fabiana Marnetto, Paola Valentino, et al. "Rituximab-induced hypogammaglobulinemia in patients with neuromyelitis optica spectrum disorders." Neurology - Neuroimmunology Neuroinflammation 5, no. 6 (2018): e498. http://dx.doi.org/10.1212/nxi.0000000000000498.

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ObjectiveTo evaluate the long-term effects of rituximab (RTX) on total and specific immunoglobulins (Igs) in patients with neuromyelitis optica spectrum disorders (NMOSDs).MethodsTotal IgG, IgA, and IgM levels were evaluated in 15 patients with NMOSDs treated with RTX (median follow-up 70 months). Anti-aquaporin 4 (AQP4)-IgG titration was performed on samples from 9 positive patients. Anti-tetanus (TET), anti-varicella-zoster virus (VZV), and anti-Epstein–Barr virus nuclear antigen (EBNA) IgGs were also tested in patients with NMOSDs and in 6 healthy controls (HCs).ResultsRTX reduced total IgG

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Puspitasari, Carina Shelia, Fasihah Irfani Fitri, and Kiking Ritarwan. "Correlation between IgG Anti-Toxoplasmosis Gondii Antibodies and Cognitive Function in Human Immunodeficiency Virus-Acquired Immunodeficiency Syndrome (HIV-AIDS) Patients with Cerebral Toxoplasmosis." Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) 5, no. 3 (2023): 116–26. http://dx.doi.org/10.32734/jetromi.v5i3.12049.

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Background: Patients with HIV-AIDS are at increased risk for both opportunistic infections, such as cerebral toxoplasmosis, and cognitive impairment. IgG anti-Toxoplasmosis gondii (T.gondii) is a marker for latent infection. However, its role in cognition in HIV patients remains unclear. The study aims to determine the correlation between Ig-G anti-T.gondii and each domain cognitive function in HIV patients with cerebral toxoplasmosis. Method: This was a cross-sectional study involving 110 HIV patients with cerebral toxoplasmosis who met the inclusion and exclusion criteria. We assessed cognit

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Sokurova, Alla Mikhaylovna. "Specific laboratory diagnosis of viral hepatitis." Pediatrician (St. Petersburg) 5, no. 3 (2014): 96–100. http://dx.doi.org/10.17816/ped5396-100.

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During the last years, the incidence of chronic forms of viral hepatitis has increased. This necessitates the need for a reliable and timely means of diagnosis, which have been improved progressively. The list of markers of infection has been expanding, and the appropriate interpretation of this data would allow doctors to make the choice of treatment required for each particular case. The following methods are used for diagnosis of viral hepatitis: immunno-electron microscopy (IEM), enzyme-linked immunosorbent assay (ELISA), polymerase chain reaction (PCR). The markers of acute hepatitis A ar

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Fadeyi, Emmanuel A., Tawfeq Naal, Mary Green, Julie H. Simmons, Mary Rose Jones, and Gregory J. Pomper. "Anti-M–Induced Delayed Hemolytic Transfusion Reaction." Laboratory Medicine 51, no. 4 (2019): 426–29. http://dx.doi.org/10.1093/labmed/lmz078.

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Abstract Background Anti-M is most often assumed to be naturally occurring and can be comprised of a mixture of predominantly immunoglobulin(Ig)M with a lesser IgG component. Anti-M-antibodies usually do not react at 37°C and therefore are considered to be of little clinical significance. Methods A 28-year-old man presented with hemorrhagic shock from numerous injuries sustained in a motor vehicle collision. The patient received several units of red blood cells (RBCs). The antibody screen, the direct antiglobulin test (DAT), and the RBC genotype were sent for laboratory evaluation. Results A t

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Gorban, Nataliia E., Irina B. Vovk, Iryna M. Nikitina, Valentina K. Kondratiuk, and Nadiia O. Yemets. "IMMUNOGLOBULIN INDICATORS TO VIRUSES CYTOMEGAL AND GENITAL HERPES IN THE BLOOD SERUM OF WOMEN WITH NON-ATIPICAL ENDOMETRIAL HYPERPROLIFETATIVE PATHOLOGY." Wiadomości Lekarskie 73, no. 8 (2020): 1600–1604. http://dx.doi.org/10.36740/wlek202008102.

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The aim of the study was to analyze the level of Ig M- and Ig G-antibody (Ab) for cytomegalovirus (CMV) and herpes simplex virus type 2 (HSV-2) in serum of women with non-atypical endometrial hyperproliferative pathology. Materials and methods: The analysis of immunoglobulin indices to CMV and HSV-2 in serum of women with non-atypical endometrial hyperproliferative pathology. In women with uterine body polyps the presence of CMV in the uterine cavity was found in 54.8% of cases, in women with non-atypical endometrial hyperplasia in 38.3% of cases. The levels of Ig G-Ab and Ig M-Ab to CMV in se

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Jia, Xinyan, Xiangxin Liu та Wenzhong Yang. "Predictive Value Analysis of Serum Ig A, Ig G, and TNF-α in Recurrence of Multiple Myeloma". Disease Markers 2022 (12 жовтня 2022): 1–7. http://dx.doi.org/10.1155/2022/2095696.

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Objective. The study is aimed at analyzing the predictive value of serum Ig A, Ig G, and TNF-α in the recurrence of multiple myeloma (MM). Methods. 136 patients with MM treated in our hospital from January 2010 to January 2017 were followed up for 5 years. Finally, 100 patients who met the inclusion and exclusion criteria and had the complete follow-up visit were selected as the study subjects, with the recurrence of MM as endpoint event, and the observation was taken until the occurrence of endpoint event in patients or the termination of this study. They were divided into the recurrence grou

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Schwerer, Beatrix, Andrea Neisser, and Hanno Bernheimer. "Distinct Immunoglobulin Class and Immunoglobulin G Subclass Patterns against Ganglioside GQ1b in Miller Fisher Syndrome following Different Types of Infection." Infection and Immunity 67, no. 5 (1999): 2414–20. http://dx.doi.org/10.1128/iai.67.5.2414-2420.1999.

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ABSTRACT We studied serum antibodies against gangliosides GQ1b and GM1 in 13 patients with Miller Fisher syndrome (MFS) and in 18 patients with Guillain-Barré syndrome (GBS) with cranial nerve involvement. Anti-GQ1b titers were elevated in all patients with MFS cases (immunoglobulin G [IgG] > IgA, IgM), and in 8 of the 18 with GBS. Lower frequencies of increased anti-GM1 titers were observed in MFS patients (3 of 13), as well as in GBS patients (5 of 18). During the course of MFS, anti-GQ1b titers of all Ig classes decreased within 3 weeks after onset. By contrast, anti-GM1 titers (mainly

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Arfijanto, M. Vitanata, and Isty Rindryastuti. "A Patient with Typhoid Hepatitis." Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy 22, no. 2 (2021): 154–58. http://dx.doi.org/10.24871/2222021154-158.

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Typhoid hepatitis is typhoid fever accompanied by symptoms of jaundice, hepatomegaly and abnormal liver function tests. The incidence varies between 0.4% -26% of typhoid fever patients. We report a case of a 34-year-old male, presented with fever, epistaxis, gastrointestinal symptoms, thrombocytopenia and elevated AST/ ALT, thus the patient was first diagnosed as dengue hemorrhagic fever grade II. On day 9th the signs and symptoms were persisted, Ig M and Ig G Dengue was negative. Then we evaluated the virus marker for hepatitis and blood culture. The results were negative for HBsAg, anti HCV

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Ismail, Ashraf, Khalid A. Enan, Abdel Rahim M. El-Hussein, Hala Ibrahim, Hajar A. Gsemalseed, and Abdel-Moniem Eltayeb Abdo. "Aggravating Effects of Hepatitis E Virus Infection on Patients with Chronic Liver Disease in Ibn-Sina Hospital Sudan." Asian Journal of Research in Infectious Diseases 13, no. 2 (2023): 44–51. http://dx.doi.org/10.9734/ajrid/2023/v13i2264.

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Background: Hepatitis E virus (HEV) is one of the most common causes of acute hepatitis. Sudan is considered as hyper-endemic for HEV. HEV infection in patients with preexisting chronic liver diseases (CLDs) has been reported to result in severe clinical manifestations and poor outcomes. However data on the role of HEV infection in worsening of pre-existing CLD are limited. Objective: To determine hepatitis E virus (HEV) infection and its effect on severity of CLD. Methods: A descriptive cross-sectional study that consecutively enrolled 87 CLD patients in Ibn-Sina Specialized Hospi

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Yu, Zheng, Meiying Zhang, Hongyang Jing, et al. "Characterization of LRP4/Agrin Antibodies From a Patient With Myasthenia Gravis." Neurology 97, no. 10 (2021): e975-e987. http://dx.doi.org/10.1212/wnl.0000000000012463.

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Background and ObjectiveTo determine whether human anti-LRP4/agrin antibodies are pathogenic in mice and to investigate underpinning pathogenic mechanisms.MethodsImmunoglobulin (Ig) was purified from a patient with myasthenia gravis (MG) with anti-LRP4/agrin antibodies and transferred to mice. Mice were characterized for body weight, muscle strength, twitch and tetanic force, neuromuscular junction (NMJ) functions including compound muscle action potential (CMAP) and endplate potentials, and NMJ structure. Effects of the antibodies on agrin-elicited muscle-specific tyrosine kinase (MuSK) activ

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Mast, Jan, Johan Buyse, and Bruno M. Goddeeris. "Dietary L-carnitine supplementation increases antigen-specific immunoglobulin G production in broiler chickens." British Journal of Nutrition 83, no. 2 (2000): 161–66. http://dx.doi.org/10.1017/s0007114500000209.

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The usefulness of supplementary dietary L-CARNITINE AS AN IMMUNOMODULATOR TO INCREASE ANTIGEN-SPECIFIC ANTIBODY LEVELS WAS ANALYSED IN 2–6-WEEK-OLD BROILERS. THE CHICKENS RECEIVED COMMERCIAL FEEDS EITHER UNSUPPLEMENTED (STARTER FEED 17·8 MG CARNITINE/KG, FINISHER DIET 22·9 MG CARNITINE/KG) OR SUPPLEMENTED WITH l-carnitine (100 mg carnitine/kg added to feed). At 14 d of age, both groups were distributed in equal numbers and sex ratios over two environmentally controlled chambers where temperature (28°) was either reduced immediately to 20°, or gradually to 22° at 36 d of age. Antigen-specific i

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Dhani Redhono Harioputro, Nurhasan Agung Prabowo, Fatna Andika Wati, Indrayana Sunarso, Arie Kusumawardani, and Arsyi Dasa Ramadhan. "Indirect contact increases antibody titers in people exposed to Anthrax." GSC Biological and Pharmaceutical Sciences 25, no. 2 (2023): 405–10. http://dx.doi.org/10.30574/gscbps.2023.25.2.0506.

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Introduction: Anthrax is a zoonotic infection that often becomes epidemic in endemic areas. It can be transmitted to humans through contact with infected animals. The most common manifestation is the appearance of eschar on the skin. Early detection as a screening for anthrax exposure can use serum anti PA Ig G antibody tests. This study aims to analyze the contact history and appearance of eschar on the skin against serum antibodies of people exposed to anthrax. Material and Methods: This analytical observational study used a cross-sectional design. It assessed the relationship of contact his

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Fraser, Douglas D., Gediminas Cepinskas, Marat Slessarev, et al. "Critically Ill COVID-19 Patients Exhibit Anti-SARS-CoV-2 Serological Responses." Pathophysiology 28, no. 2 (2021): 212–23. http://dx.doi.org/10.3390/pathophysiology28020014.

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Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is a global health care emergency. Anti-SARS-CoV-2 serological profiling of critically ill COVID-19 patients was performed to determine their humoral response. Blood was collected from critically ill ICU patients, either COVID-19 positive (+) or COVID-19 negative (−), to measure anti-SARS-CoV-2 immunoglobulins: IgM; IgA; IgG; and Total Ig (combined IgM/IgA/IgG). Cohorts were similar, with the exception that COVID-19+ patients had a greater body mass indexes, developed bilateral pneumonias more frequently and suffered increased hypoxia

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Hivroz, C., B. Gény, J. C. Brouet, and C. Grillot-Courvalin. "Altered signal transduction secondary to surface IgM cross-linking on B-chronic lymphocytic leukemia cells. Differential activation of the phosphatidylinositol-specific phospholipase C." Journal of Immunology 144, no. 6 (1990): 2351–58. http://dx.doi.org/10.4049/jimmunol.144.6.2351.

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Abstract To further study the mechanisms by which surface Ig triggering activates the inositol phospholipid signaling pathway, we have used B cells from chronic lymphocytic leukemia patients which, as previously described, display two patterns of response upon sIg cross-linking: in one group this cross-linking induces an inositol phosphate release, an intracellular free Ca2+ concentration elevation and a subsequent cell proliferation; in a second group none of these events occur although there is an increased class II Ag expression following anti-mu stimulation as in the first group. We have b

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Burri, E., and R. Meier. "Mangelernährung im Spital – Eine Pilotstudie." Praxis 97, no. 12 (2008): 657–63. http://dx.doi.org/10.1024/1661-8157.97.12.657.

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Hintergrund: Die Mangelernährung bei hospitalisierten Patienten wird noch zu selten erfasst und meist keine Ernährungstherapie eingeleitet. Methoden: Pilotstudie mit konsekutiver Erfassung von 50 stationären Patienten bei Spitaleintritt mittels Nutritional Risk Score (NRS). Beginn einer Ernährungstherapie bei NRS ≥ 3 (Interventionsgruppe, IG), normale Spitalkost bei NRS < 3 (Nicht-Interventionsgruppe, NIG). Bei allen Patienten wurden Gewicht, Body-Mass-Index, Albumin und Transferrin bei Eintritt und Austritt erfasst. Die tägliche Kalorien- und Proteinzufuhr wurde mit dem errechneten Tagesbe

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Phan, Tri Giang, Michelle Amesbury, Sandra Gardam, et al. "B Cell Receptor–independent Stimuli Trigger Immunoglobulin (Ig) Class Switch Recombination and Production of IgG Autoantibodies by Anergic Self-Reactive B Cells." Journal of Experimental Medicine 197, no. 7 (2003): 845–60. http://dx.doi.org/10.1084/jem.20022144.

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In both humans and animals, immunoglobulin (Ig)G autoantibodies are less frequent but more pathogenic than IgM autoantibodies, suggesting that controls over Ig isotype switching are required to reinforce B cell self-tolerance. We have used gene targeting to produce mice in which hen egg lysozyme (HEL)-specific B cells can switch to all Ig isotypes (SWHEL mice). When crossed with soluble HEL transgenic (Tg) mice, self-reactive SWHEL B cells became anergic. However, in contrast to anergic B cells from the original nonswitching anti-HEL × soluble HEL double Tg model, self-reactive SWHEL B cells a

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Harnett, M. M., and G. G. Klaus. "G protein coupling of antigen receptor-stimulated polyphosphoinositide hydrolysis in B cells." Journal of Immunology 140, no. 9 (1988): 3135–39. http://dx.doi.org/10.4049/jimmunol.140.9.3135.

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Abstract Cross-linking of the IgM and IgD Ag-R on mature B lymphocytes provokes the rapid hydrolysis of phosphatidylinositol 4,5-bisphosphate. We show here that in permeabilized, [3H]inositol-labeled mouse B cells the nonhydrolyzable GTP analogue GTP gamma S induces release of inositol phosphates, including inositol trisphosphate. The response is markedly augmented by the addition of polyclonal anti-Ig or anti-mu or anti-delta mAb. Inositol phosphate release provoked in intact B cells by any of the anti-receptor antibodies was not inhibited by pertussis toxin and only partially inhibited by ch

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González-Gross, Marcela, Carlos Quesada-González, Javier Rueda, et al. "Analysis of Effectiveness of a Supplement Combining Harpagophytum procumbens, Zingiber officinale and Bixa orellana in Healthy Recreational Runners with Self-Reported Knee Pain: A Pilot, Randomized, Triple-Blind, Placebo-Controlled Trial." International Journal of Environmental Research and Public Health 18, no. 11 (2021): 5538. http://dx.doi.org/10.3390/ijerph18115538.

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Recreational running (RR) is becoming a popular way to increase physical activity for improving health, together with a higher incidence of knee injuries. The aim was to analyze the effect of a four-week supplementation with a mixture of Harpagophytum procumbens, Zingiber officinale and Bixa orellana on males, middle-aged, RR with an undiagnosed knee discomfort. A randomized triple-blind placebo-control trial was conducted among male RR aged 40–60 years suffering from self-declared knee discomfort after training. Participants were assigned to supplementation (2 g/day in 6 doses; n = 13; interv

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Nurinasari, Hafi, Sajidan, Bambang Purwanto, Dono Indarto, and Didik T. Subekti. "Effect of Toxoplasma Infection Dosage on Igg, Igm, Fetus Weight and Body Length, and Necrosis of Placenta and Fetal Heart." HAYATI Journal of Biosciences 31, no. 3 (2024): 596–602. http://dx.doi.org/10.4308/hjb.31.3.596-602.

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One of the most prevalent zoonotic illnesses in the world, toxoplasmosis, affects both humans and animals and is caused by the parasite Toxoplasma gondii. The infection will trigger the immune system to increase antibody production. This study aims to determine the dose of toxoplasma that causes necrosis in rats placental and fetal hearts. This study was laboratory experimental research with a Randomized Control Trial (RCT). The study design used a post-test only with a control group design. The Ig G variable obtained from the control group (CG) and treatment group 3 (TG3) is the most signific

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Parija, SubhashChandra, and GireeshA Raman. "Anti-Taenia solium larval stage Ig G antibodies in patients with epileptic seizures." Tropical Parasitology 1, no. 1 (2011): 20. http://dx.doi.org/10.4103/2229-5070.72113.

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Parija, SubhashChandra, and GireeshA Raman. "Anti-Taenia solium larval stage Ig G antibodies in patients with epileptic seizures." Tropical Parasitology 1, no. 1 (2010): 20. http://dx.doi.org/10.4103/0000-0205.72113.

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Dhani, Redhono Harioputro, Agung Prabowo Nurhasan, Andika Wati Fatna, Sunarso Indrayana, Kusumawardani Arie, and Dasa Ramadhan Arsyi. "Indirect contact increases antibody titers in people exposed to Anthrax." GSC Biological and Pharmaceutical Sciences 25, no. 2 (2023): 405–10. https://doi.org/10.5281/zenodo.10610118.

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<strong>Introduction: </strong>Anthrax is a zoonotic infection that often becomes epidemic in endemic areas. It can be transmitted to humans through contact with infected animals. The most common manifestation is the appearance of <em>eschar</em> on the skin. Early detection as a screening for anthrax exposure can use serum anti PA Ig G antibody tests. This study aims to analyze the contact history and appearance of <em>eschar</em> on the skin against serum antibodies of people exposed to anthrax. <strong>Material and Methods: </strong>This analytical observationa

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Winder, N. Christine, and Roland von Fellenberg. "Immunofluorescent evaluation of the lower respiratory tract of healthy horses and of horses with chronic bronchiolitis." American Journal of Veterinary Research 47, no. 6 (1986): 1271–74. https://doi.org/10.2460/ajvr.1986.47.06.1271.

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SUMMARY Pulmonary parenchymal tissues from 6 healthy horses and from 9 horses with chronic bronchiolitis were evaluated by use of an indirect immunofluorescent technique. In horses of both groups, the diffuse interstitial immunofluorescence was most intense for immunoglobulin (Ig)G, moderate for IgA, and minimal for IgM. Intensity of fluorescence was increased markedly in diseased lungs exposed to anti-IgA and anti-IgG. Around small bronchi and large bronchioles of healthy horses, IgA-containing cells generally were more numerous than were IgG-Fc fragment (Fc)-containing cells; in small bronch

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Morawetz, R. A., L. Gabriele, L. V. Rizzo, et al. "Interleukin (IL)-4-independent immunoglobulin class switch to immunoglobulin (Ig)E in the mouse." Journal of Experimental Medicine 184, no. 5 (1996): 1651–61. http://dx.doi.org/10.1084/jem.184.5.1651.

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Immunoglobulin (Ig) class switching in B cells is regulated by stimuli transduced by cytokines and cell-cell contact. Among these stimuli, interleukin (IL)-4 has been considered an absolute prerequisite for class switching to IgE in the mouse. Here we report that IL-4-deficient (IL-4-/-) and wildtype mice had comparably elevated serum IgE levels during the course of a murine retrovirus-induced immunodeficiency syndrome, MAIDS. IgE switching in IL-4-/- mice was also induced by injection of anti-IgD antibody. Treatment with anti-IgD induced germline epsilon (g epsilon) transcripts with comparabl

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Mullins, Christina Susanne, Michael Gock, Mathias Krohn, and Michael Linnebacher. "Human Colorectal Carcinoma Infiltrating B Lymphocytes Are Active Secretors of the Immunoglobulin Isotypes A, G, and M." Cancers 11, no. 6 (2019): 776. http://dx.doi.org/10.3390/cancers11060776.

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Despite the importance of tumor infiltrating B cells (TiBc) in immunological circuits, their functional role is scarcely investigated. Here, we analyzed immunoglobulin (Ig) secretion of the subtypes IgA, IgG, and IgM of TiBc from freshly resected primary and secondary colorectal carcinomas (CRC) by FluoroSpot (n = 30 CRC) directly ex vivo. High, intermediate, and low secretion was observed in 33%, 37%, and 30% of the tumors for IgA; in 10%, 27%, and 63% for IgG; and in 21%, 36%, and 50% for IgM, respectively. These ex vivo data validate our previous findings: Most TiBc present in the CRC micro

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Mejía-Martínez, K., C. Lemus-Flores, and J. F. Zambrano-Zaragoza. "Estudio comparativo en la respuesta inmune humoral de Ig M e Ig G en cerdo criollo mexicano y comercial." Archivos de Zootecnia 59, no. 226 (2008): 177–84. http://dx.doi.org/10.21071/az.v59i226.4732.

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En el presente estudio, se analizó la respuesta humoral IgG e IgM en cerdos Criollos mexicanos (Cuino (CC) y Pelón Mexicano (CPM)) y se comparó con la de cerdos comerciales (CCO) F1 Yorkshire-Landrace, para establecer diferencias que nos permitieran utilizarlos como indicador de resistencia a la enfermedad. Para ello, se analizaron 76 animales procedentes de la Unidad Académica de Medicina Veterinaria y Zootecnia de la Universidad Autónoma de Nayarit. Cerdos destetados de 45 días de edad fueron retados con la vacuna bacterina mixta porcina, que contiene cepas de Salmonella, Escherichia coli y

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Moschonis, George, Maria Michalopoulou, Konstantina Tsoutsoulopoulou, et al. "Assessment of the Effectiveness of a Computerised Decision-Support Tool for Health Professionals for the Prevention and Treatment of Childhood Obesity. Results from a Randomised Controlled Trial." Nutrients 11, no. 3 (2019): 706. http://dx.doi.org/10.3390/nu11030706.

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We examined the effectiveness of a computerised decision-support tool (DST), designed for paediatric healthcare professionals, as a means to tackle childhood obesity. A randomised controlled trial was conducted with 65 families of 6–12-year old overweight or obese children. Paediatricians, paediatric endocrinologists and a dietitian in two children’s hospitals implemented the intervention. The intervention group (IG) received personalised meal plans and lifestyle optimisation recommendations via the DST, while families in the control group (CG) received general recommendations. After three mon

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Hinton, Dennis M., and Mushtaq A. Khan. "Evaluation of the Miniature Swine for Use in Immunotoxicity Assessment: I. Quantitation of Humoral Responses to Sheep Red Blood Cells and Effects of Cyclophosphamide." Journal of the American College of Toxicology 8, no. 5 (1989): 1039–52. http://dx.doi.org/10.3109/10915818909018064.

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T-cell-dependent and t-independent humoral responses as well as cell-mediated re-sponses(1) were assessed with groups of young, Hormel-Hanford miniature swine. Test antigens established in various immunotoxicity studies with rodents were used. Results with the widely used t-dependent test antigen, sheep red blood cells (SRBC), are presented in this report. Groups of swine were immunized with varying dosages of SRBC to evaluate basal responses. Serum antibody titers were estimated by the standardized hemolysin (HLY) visual endpoint (EP) assay and a quantitative spectro-photometric (SP) variatio

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