Relevant bibliographies by topics / IGF1

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'IGF1'

Author: Grafiati
Published: 4 June 2021
Last updated: 26 July 2025

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Journal articles on the topic "IGF1"

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Juengel, Jennifer L., Lisa J. Haydon, Brigitta Mester, Brian P. Thomson, Michael Beaumont, and Douglas C. Eckery. "The role of IGFs in the regulation of ovarian follicular growth in the brushtail possum (Trichosurus vulpecula)." REPRODUCTION 140, no. 2 (2010): 295–303. http://dx.doi.org/10.1530/rep-10-0142.

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IGFs are known to be key regulators of ovarian follicular growth in eutherian mammals, but little is known regarding their role in marsupials. To better understand the potential role of IGFs in the regulation of follicular growth in marsupials, expression of mRNAs encoding IGF1, IGF2, IGF1R, IGF-binding protein 2 (IGFBP2), IGFBP4 and IGFBP5 was localized by in situ hybridization in developing ovarian follicles of the brushtail possum. In addition, the effects of IGF1 and IGF2 on granulosa cell function were tested in vitro. Both granulosa and theca cells synthesize IGF mRNAs, with the theca ex
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Ndandala, Charles Brighton, Qi Zhou, Zhiyuan Li, Yuwen Guo, Guangli Li, and Huapu Chen. "Identification of Insulin-like Growth Factor (IGF) Family Genes in the Golden Pompano, Trachinotus ovatus: Molecular Cloning, Characterization and Gene Expression." International Journal of Molecular Sciences 25, no. 5 (2024): 2499. http://dx.doi.org/10.3390/ijms25052499.

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Insulin-like growth factors (IGFs) are hormones that primarily stimulate and regulate animal physiological processes. In this study, we cloned and identified the open reading frame (ORF) cDNA sequences of IGF family genes: the insulin-like growth factor 1 (IGF1), insulin-like growth factor 2 (IGF2), and insulin-like growth factor 3 (IGF3). We found that IGF1, IGF2, and IGF3 have a total length of 558, 648, and 585 base pairs (bp), which encoded a predicted protein with 185, 215, and 194 amino acids (aa), respectively. Multiple sequences and phylogenetic tree analysis showed that the mature gol
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Frystyk, Jan, Anders J. Schou, Carsten Heuck, et al. "Prednisolone reduces the ability of serum to activate the IGF1 receptor in vitro without affecting circulating total or free IGF1." European Journal of Endocrinology 168, no. 1 (2013): 1–8. http://dx.doi.org/10.1530/eje-12-0518.

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ObjectiveEnd-point bioassays based on thymidine or sulfate incorporation have demonstrated that glucocorticoid (GC) treatment inhibits serum IGF1 action, but the mechanism is unknown as serum IGF1 concentrations have been reported to either increase or remain unchanged.AimTo investigate whether GC treatment affects the ability of serum to activate the IGF1 receptor (IGF1R) in vitro (i.e. bioactive IGF1), using a specific cell-based IGF1 kinase receptor activation assay.Subjects and methodsTwenty children with stable asthma (age 7.7–13.8 years) treated for 1 week with 5 mg prednisolone in a ran
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Kharkova, A., and O. Minchenko. "Factors and their receptor genes in glioma cells with suppressed function of ERN 1 enzyme upon glucose deprivation." Bulletin of Taras Shevchenko National University of Kyiv. Series: Problems of Physiological Functions Regulation 20, no. 1 (2016): 44–49. http://dx.doi.org/10.17721/2616_6410.2016.20.44-49.

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It was shown that the expression level of insulin like growth factors (IGF1 and IGF2) genes is decreased, but IGF receptor (IRF1R) gene is significantly increased in U87 glioma cells with suppressed activity of the sensor and signaling enzyme ERN1. In U87 glioma cells the expression level of IGF1 gene is decreased but IGF2 and IGF1R do not change significantly upon glucose deprivation condition. The inhibition of ERN1 functional activity does not affect the sensitivity of IGF1 and IGF1R gene expressions to glucose deprivation but the inhibition of ERN1 eliminates the effect of glucose deprivat
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Chisalita, S. I., G. S. Johansson, E. Liefvendahl, K. Bäck, and H. J. Arnqvist. "Human aortic smooth muscle cells are insulin resistant at the receptor level but sensitive to IGF1 and IGF2." Journal of Molecular Endocrinology 43, no. 6 (2009): 231–39. http://dx.doi.org/10.1677/jme-09-0021.

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Whether insulin, at physiological concentrations, has direct effects on vascular smooth muscle cells (VSMCs) remains controversial. Our aim was to characterize the mechanism for insulin resistance in VSMCs. For comparison, the effects of IGF1 and IGF2 were also studied. Cultured human aortic smooth muscle cells (HASMC) were used. Receptor mRNA was analyzed by quantitative reverse transcription PCR and receptor protein by ELISA and western blot. Biological effects were studied by thymidine incorporation and glucose accumulation. In HASMC, both mRNA and protein expression of IGF1 receptors (IGF1
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Gatford, K. L., G. K. Heinemann, S. D. Thompson, et al. "Circulating IGF1 and IGF2 and SNP genotypes in men and pregnant and non-pregnant women." Endocrine Connections 3, no. 3 (2014): 138–49. http://dx.doi.org/10.1530/ec-14-0068.

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Circulating IGFs are important regulators of prenatal and postnatal growth, and of metabolism and pregnancy, and change with sex, age and pregnancy. Single-nucleotide polymorphisms (SNPs) in genes coding for these hormones associate with circulating abundance of IGF1 and IGF2 in non-pregnant adults and children, but whether this occurs in pregnancy is unknown. We therefore investigated associations of plasma IGF1 and IGF2 with age and genotype at candidate SNPs previously associated with circulating IGF1, IGF2 or methylation of the INS–IGF2–H19 locus in men (n=134), non-pregnant women (n=74) a
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Díaz del Moral, Sandra, Maha Benaouicha, Ramón Muñoz-Chápuli, and Rita Carmona. "The Insulin-like Growth Factor Signalling Pathway in Cardiac Development and Regeneration." International Journal of Molecular Sciences 23, no. 1 (2021): 234. http://dx.doi.org/10.3390/ijms23010234.

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Insulin and Insulin-like growth factors (IGFs) perform key roles during embryonic development, regulating processes of cell proliferation and survival. The IGF signalling pathway comprises two IGFs (IGF1, IGF2), two IGF receptors (IGFR1, IGFR2), and six IGF binding proteins (IGFBPs) that regulate IGF transport and availability. The IGF signalling pathway is essential for cardiac development. IGF2 is the primary mitogen inducing ventricular cardiomyocyte proliferation and morphogenesis of the compact myocardial wall. Conditional deletion of the Igf1r and the insulin receptor (Insr) genes in the
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Mashayekhi, Farhad, Somayeh Shabani, and Zivar Salehi. "Comparison of serum IGF1, IGF2 and IGFBP1-6 concentration in the children with different stages of autism spectrum disorders." Archives of Psychiatry and Psychotherapy 24, no. 3 (2022): 20–24. http://dx.doi.org/10.12740/app/144882.

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Aim of the studyAutism spectrum disorder (ASD) is a neurodevelopmental condition considered by early-onset difficulties in social communication. Insulin-like growth factors (IGFs) play crucial roles in synapse formation. Most of circulating IGFs are bound to IGF-binding proteins (IGFBPs) that modify IGF action. IGFBPs prolong the plasma half-life of IGFs. In this project we studied the association of IGF1/2 and IGFBP1-6 serum concentration with the severity of ASD (Levels 1-3; Mild, Moderate and severe, respectively).Subject or material and methodsA hundred and eighty patients with ASD (Mild;
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Minchenko, Dmytro O., A. P. Kharkova, O. V. Halkin, L. L. Karbovskyi, and O. H. Minchenko. "Effect of hypoxia on the expression of genes encoding insulin-like growth factors and some related proteins in U87 glioma cells without IRE1 function." Endocrine Regulations 50, no. 2 (2016): 43–54. http://dx.doi.org/10.1515/enr-2016-0008.

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AbstractObjective. The aim of the present study was to investigate the effect of hypoxia on the expression of genes encoding insulin-like growth factors (IGF1 and IGF2), their receptor (IGF1R), binding protein-4 (IGFBP4), and stanniocalcin 2 (STC2) in U87 glioma cells in relation to inhibition of endoplasmic reticulum stress signaling mediated by IRE1 (inositol requiring enzyme 1) for evaluation of their possible significance in the control of tumor growth. Methods. The expression of IGF1, IGF2, IGF1R, IGFBP4, and STC2 genes in U87 glioma cells transfected by empty vector pcDNA3.1 (control) an
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Hernández, Rocío, Gimena Gomez Castro, Fernanda Mariel Rodriguez, Luciano Casas, and Enrique Portiansky. "Insulin-like growth factors in cat placenta." Analecta Veterinaria 44 (February 18, 2025): 090. https://doi.org/10.24215/15142590e090.

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Placental development involves maternal-fetal signalling events, and it is an under-researched topic in feline reproduction. Few studies of endotheliochorial placentas deal with insulin-like growth factors (IGFs), which are among the principal developmental regulators. While placental expression of IGFs and type 1 IGF receptor (IGF1R) has already been reported in bitches, data regarding the IGF system in queens are limited to uterine tissues. This study aimed to detect IGF1, IGF2, and IGF1R in fetal and maternal placental structures. Samples from twenty-three placentas were classified into one
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Dissertations / Theses on the topic "IGF1"

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Dias, Elaine Oliveira. "Expressão do fator de crescimento similar à insulina 1 e 2 (IGF1 e IGF2) e receptor de IGF1 (IGF1R) no carcinoma papilífero da tireoide." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/5/5135/tde-24022015-110719/.

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INTRODUÇÃO: Acredita-se que os fatores de crescimento insulina símile 1 (IGF1) e IGF2 tenham um papel chave na progressão de tumores, resistência à apoptose e terapias. A resistência à insulina tem sido associada ao aumento do volume tireoidiano e aumento do risco de desenvolver nódulos e câncer de tireoide; no entanto, há poucos estudos que avaliaram o papel dos IGFs e seus receptores no carcinoma papilífero de tireoide (CPT) e, até o momento, nenhum estudo foi conclusivo sobre a relação entre a via insulina/IGF e o comportamento do CPT. OBJETIVOS: 1) Estudar a expressão do IGF1, IGF2 e o IGF
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Jakoby, Judith Martina [Verfasser], and Regine [Akademischer Betreuer] Süss. "Aktives liposomales Targeting IGF1-Rezeptor-exprimierender Tumoren." Freiburg : Universität, 2014. http://d-nb.info/1123481849/34.

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Wallborn, Tillmann. "Klinisches Erscheinungsbild und zugrundeliegende molekularbiologische Mechanismen der heterozygoten V599E-IGF-I Rezeptormutation." Doctoral thesis, Universitätsbibliothek Leipzig, 2012. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-90100.

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Untersuchungen haben gezeigt, dass unterdurchschnittlich leichte Neugeborene für zahlreiche Erkrankungen ein erhöhtes Risiko tragen. Beschrieben ist unter anderem das vermehrte Auftreten psychosozialer Probleme sowie metabolischer und kardiovaskulärer Spätfolgen. Inzwischen sind zahlreiche mögliche Ursachen einer intrauterinen und postnatalen Wachstumsretardierung beschrieben worden. Unter diesen Ursachen finden sich auch genetische Veränderungen von Proteinen der endokrinologischen Wachstumsregulierung. So wurden Mutationen im GH1 Gen, in Entwicklungsgenen von GH produzierenden Zellen, im IGF
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Harmel, Eva-Maria Sophia. "Klinisches Erscheinungsbild und funktionelle Charakterisierung eines Patienten mit einer heterozygoten Exon 6 Deletion im IGF1R." Doctoral thesis, Universitätsbibliothek Leipzig, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-163923.

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Hintergrund: Der Insulin-like growth factor receptor (IGF1R) spielt eine zentrale Rolle bei Wachstumsprozessen. Heterozygote IGF1R-Mutationen führen durch eine partielle IGF1-Resistenz zu Kleinwuchs. Methoden: Auxologische und endokrinologische Daten des Patienten wurden erhoben. Anhand von Fibroblasten wurde die IGF1R-Deletion charakterisiert und die Auswirkungen auf die mRNA- und Protein-Expression sowie die Signaltransduktion untersucht. Ergebnisse: Der Junge, der eine heterozygote Exon 6 Deletion im IGF1R – durch Alu-Rekombination verursacht – und eine heterozygote SHOX-Variante (p.Met24
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Müller, Eva. "Klinische und funktionelle Charakterisierung einer stark wachstumsretardierten Patientin mit einer zusammengesetzten heterozygoten Pericentrinmutation und einer heterozygoten IGF1-Rezeptor Mutation." Doctoral thesis, Universitätsbibliothek Leipzig, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-131321.

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Die menschliche Entwicklung ist charakterisiert durch ein rasches fetales Wachstum, ein langsames postnatales Wachstum, ein kontinuierliches Wachstum im Laufe der Kindheit sowie einen Wachstumsschub während der Pubertät. In den letzten Jahren wurde gezeigt, dass Mutationen in den Genen des Pericentrins (PCNT) und des Insulin-like growth factor-1 Rezeptors (Insulin ähnlicher Wachstumsfaktor Typ 1 Rezeptor, IGF1R) seltene Auslöser von prä- und postnataler Wachstumsrestriktion darstellen können. In dieser Arbeit wird eine stark wachstumsretardierte Patientin mit zusammengesetzter heterozygoter PC
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Besen, Lisia Schaefer. "Concentração de IGF1 livre e insulina no fluido folicular e a expressão folicular dos receptores de IGF1 durante a foliculogênese da égua." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2016. http://hdl.handle.net/10183/150241.

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O objetivo deste estudo foi analisar as concentrações do fator de crescimento semelhante à insulina tipo 1 (IGF1) e insulina (INS) no fluido folicular durante foliculogênese em éguas, e localizar o receptor tipo 1 de IGF (IGF1R) nas paredes foliculares. Durante a estação reprodutiva, 40 éguas mestiças enviadas para abate em matadouro, com idades variando entre 6 e 16 anos foram utilizadas. As éguas foram abatidas de forma humanitária. Os tratos reprodutivos internos foram recuperados dentro de 10 min após o abate, ovários de éguas cíclicas foram separados do resto do aparelho. As éguas foram c
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Schneider, Harald Jörn, Nele Friedrich, Jens Klotsche, et al. "Prediction of incident diabetes mellitus by baseline IGF1 levels." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2013. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-100978.

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Objective: IGF1 is associated with metabolic parameters and involved in glucose metabolism. Low-IGF1 has been implicated in the etiology of glucose intolerance and subjects with pathological causes of either low- or high-IGF1 are at risk of diabetes. We hypothesized that both low- and high-IGF1 levels increase the risk of diabetes and aimed to assess the role of IGF1 in the risk of developing diabetes in a large prospective study. Design: An analysis of two prospective cohort studies, the DETECT study and SHIP. Methods: We measured IGF1 levels in 7777 nondiabetic subjects and assessed incide
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Parente, Pereira A. C. "Study of two bipolar susceptibility genes : Slynar and IGF1." Thesis, University College London (University of London), 2009. http://discovery.ucl.ac.uk/18571/.

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Linkage studies have implicated the 12q22-24 region in susceptibility to bipolar disorder. In this region alleles at the “Slynar” and Insulin Like Growth Factor 1 (IGF1) genes showed association with bipolar disorder. The Slynar gene is contained within a region of 278 kb on chromosome 12q24 and expresses the sequence AY070435 in the human brain. AY070435 has no known function. A Macaque brain expressed cDNA which is highly homologous to human AY070435 has been cloned and sequenced. To further characterise the human Slynar gene and expressed mRNA transcript studies were carried out to identify
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Schneider, Harald Jörn, Nele Friedrich, Jens Klotsche, et al. "Prediction of incident diabetes mellitus by baseline IGF1 levels." BioScientifica, 2011. https://tud.qucosa.de/id/qucosa%3A26329.

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Objective: IGF1 is associated with metabolic parameters and involved in glucose metabolism. Low-IGF1 has been implicated in the etiology of glucose intolerance and subjects with pathological causes of either low- or high-IGF1 are at risk of diabetes. We hypothesized that both low- and high-IGF1 levels increase the risk of diabetes and aimed to assess the role of IGF1 in the risk of developing diabetes in a large prospective study. Design: An analysis of two prospective cohort studies, the DETECT study and SHIP. Methods: We measured IGF1 levels in 7777 nondiabetic subjects and assessed incide
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Silva, Liliana de Jesus Vieira da. "Central effects of insulin and IGF1 in diabetic neuropathy." Master's thesis, Universidade de Aveiro, 2010. http://hdl.handle.net/10773/8778.

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Mestrado em Biologia Molecular e Celular<br>Este estudo avaliou se o tratamento de ratos diabéticos induzidos com estreptozotocina, com insulina ou factor de crescimento derivado da insulina (IGF1), em doses que não revertem a hiperglicemia, afectam os sinais comportamentais da neuropatia diabética e a ativação neuronal na medula espinhal. Foi também avaliada a participação de algumas das principais áreas do tronco cerebral (VLPAG), envolvidas na modulação descendente da dor. Uma semana após a indução da diabetes, foi iniciado o tratamento dos animais, 3 vezes por semana durante 3 seman
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Books on the topic "IGF1"

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Chang, Hye Rim. Studies Defining The Local Function of Adipose Tissue IGF1 And The Role of Lipolysis in Adipose Tissue Macrophage Lipid Uptake. [publisher not identified], 2015.

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Jin, Shuanggen, and Riccardo Barzaghi, eds. IGFS 2014. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-39820-4.

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Rosenfeld, Ron G., and Charles T. Roberts, eds. The IGF System. Humana Press, 1999. http://dx.doi.org/10.1007/978-1-59259-712-3.

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Müller, Eugenio E., ed. IGFs in the Nervous System. Springer Milan, 1998. http://dx.doi.org/10.1007/978-88-470-2246-1.

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E, Müller E., ed. IGFs in the nervous system. Springer, 1998.

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Blackman, Marc R., Jesse Roth, S. Mitchell Harman, and Jay R. Shapiro, eds. GHRH, GH, and IGF-I. Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-0807-5.

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Colloque médecine et recherche (8th : 2008 Paris, France). IGFs: Local repair and survival factors throughout life span. Springer, 2010.

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Houston, M. Sue, Jeffrey M. P. Holly, and Eva L. Feldman, eds. IGF and Nutrition in Health and Disease. Humana Press, 2004. http://dx.doi.org/10.1007/978-1-59259-795-6.

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Sue, Houston M., Holly Jeffrey M. P, and Feldman Eva L, eds. IGF and nutrition in health and disease. Humana Press, 2005.

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Binder, Cathrin. Untersuchungen zur Expression der Gene IGF2 und H19 in kultivierten Hautfibroblasten von Kindern mit Silver-Russell-Syndrom und Epimutation des IGF2/H19-Locus. s.n.], 2014.

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Book chapters on the topic "IGF1"

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Mancini, Antonio, Carmine Bruno, Andrea Palladino, Edoardo Vergani, and Elena Giacchi. "GH–IGF1 axis in spermatogenesis and male fertility." In Molecular Signaling in Spermatogenesis and Male Infertility. CRC Press, 2019. http://dx.doi.org/10.1201/9780429244216-6.

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de Siqueira, Flávia Ramos, Luzia Naôko Shinohara Furukawa, and Joel Claudio Heimann. "Igf1 DNA Methylation, Epigenetics, and Low-Salt Diet in Fetal Programming." In Handbook of Nutrition, Diet, and Epigenetics. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-55530-0_6.

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de Siqueira, Flávia Ramos, Luzia Naôko Shinohara Furukawa, and Joel Claudio Heimann. "Igf1 DNA Methylation, Epigenetics, and Low-Salt Diet in Fetal Programming." In Handbook of Nutrition, Diet, and Epigenetics. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-31143-2_6-1.

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Robinson, Iain C. A. F. "GH & IGF1: Aspects of Global and Local Release and Actions." In Research and Perspectives in Endocrine Interactions. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-04302-4_1.

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Werner, Haim, Zohar Attias-Geva, Itay Bentov, et al. "Cancer Genes, Tumor Suppressors, and Regulation of IGF1-R Gene Expression in Cancer." In Insulin-like Growth Factors and Cancer. Springer US, 2011. http://dx.doi.org/10.1007/978-1-4614-0598-6_8.

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Homm, C., F. Kainer, A. Holk, T. Heinze, and J. W. Dudenhausen. "Zusammenhang zwischen IGF1 im Nabelvenenblut, Geburtsgewicht, Plazentagewicht und Nabelschnurinsulin bei Neugeborenen am Termin." In Gynäkologie und Geburtshilfe 1992. Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-77857-5_660.

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Weeks, Kate L., Bianca C. Bernardo, Jenny Y. Y. Ooi, Natalie L. Patterson, and Julie R. McMullen. "The IGF1-PI3K-Akt Signaling Pathway in Mediating Exercise-Induced Cardiac Hypertrophy and Protection." In Advances in Experimental Medicine and Biology. Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-4304-8_12.

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Septian, Wike Andre, Ari Ardiantoro, Kuswati, Muhaimin Rifa’i, Mohammad Alessandro Nalaprily Bagus Prasetya, and Suyadi. "Identification of IGF1 Gene Polymorphisms Using PCR-RFLP in Indigenous Goats of East Java." In Advances in Biological Sciences Research. Atlantis Press International BV, 2025. https://doi.org/10.2991/978-94-6463-670-3_48.

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Novianti, Irida, Suyadi, Veronica M. A. Nurgiartiningsih, and Sri Rahayu. "A Variant of Insulin like Growth Factor 1 (IGF1) Gene Affects Body Conformation Traits in Madura Bulls." In Advances in Biological Sciences Research. Atlantis Press International BV, 2023. http://dx.doi.org/10.2991/978-94-6463-116-6_45.

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McMullen, Julie R., and Seigo Izumo. "Role of the Insulin-Like Growth Factor 1 (IGF1)/Phosphoinositide-3-Kinase (PI3K) Pathway Mediating Physiological Cardiac Hypertrophy." In Novartis Foundation Symposia. John Wiley & Sons, Ltd, 2008. http://dx.doi.org/10.1002/0470029331.ch7.

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Conference papers on the topic "IGF1"

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Meyer, Karolin F. M., Susanne Krauss-Etschmann, Rikst Nynke Verkaik-Schakel, et al. "Pregnancy smoking: Tissue- and sex-specific drift of Igf1r and Igf1 methylation in mouse fetuses and neonates." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.oa2947.

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Cedano Prieto, Dora M., Jessica Yu, Yoko Takada та Yoshikazu Takada. "Abstract LB-007: Interaction between integrin α4β1 and IGF1 and its role in IGF signaling in hematologic malignancies". У Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-lb-007.

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Kozlov, D. S., S. A. Rodimova, D. P. Krylov, A. M. Mozherov, M. V. Zyuzin, and D. S. Kuznetsova. "ANALYSIS OF THE EFFICIENCY OF MIRNA DELIVERY USING NANOPARTICLES IN EX VIVO TISSUE SLICES OF THE LIVER." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-333.

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The study is aimed at selecting the optimal carrier for miRNA delivery. In the course of the study, miRNAs targeting insulin-like growth factor 1 were selected. The distribution and cytotoxicity of several types of nanoparticles were analyzed using a model of liver tissue explants and multiphoton microscopy. The efficiency of suppression of IGF1 expression was assessed using stem-loop PCR, RT-PCR and ELISA.
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Shafiee, Mohamad Nasir, Abdul Muzhill Hannaan Abdul Hafizz, Reena Rahayu Md Zin, et al. "IGF1 and PTEN expressions prognosticate outcomes in endometrioid endometrial cancer (EEC)." In ASGO 2023. Korean Society of Gynecologic Oncology, 2024. http://dx.doi.org/10.3802/jgo.2024.35.s1.0061.

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Osuka, Satoru, Oltea Sampetrean, Takatsune Shimizu, et al. "Abstract 238: IGF1 receptor signaling regulates adaptive radioprotection in glioma stem cells." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-238.

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Bhattacharya, Soumyaroop, Sorachai Srisuma, Siva Kumar Solleti, et al. "Misexpression Of Asporin, A Unique IGF1-Regulated Extracellular Matrix Proteoglycan, In Bronchopulmonary Dysplasia." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a1210.

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LeRoy, Elizabeth C., Elizabeth T. Jacobs, Erin L. Ashbeck, et al. "Abstract 2853: Genetic variation in IGF1, GHR, and IGFBP1 is associated with colorectal cancer." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-2853.

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Kopantseva, Marina R., Eugenia Usova, Arsen Mikaelyan, et al. "Abstract 1540: Effect of IGF1 on cancer and stromal cells of human pancreatic tumors." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-1540.

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Gao, F., C. Li, B. Zhou, Z. Borok, S. Bellusci, and P. Minoo. "Gene Regulatory Network View of IGF1 Signaling in Secondary Crest Myofibroblasts During Postnatal Alveologenesis." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a5984.

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Somri-Gannam, L., S. Meisel Sharon, S. Hantisteanu, M. Hallak, and I. Bruchim. "72 The involvement of IGF1 axis in dendritic cells differentiation in epithelial ovarian cancer." In IGCS Annual 2019 Meeting Abstracts. BMJ Publishing Group Ltd, 2019. http://dx.doi.org/10.1136/ijgc-2019-igcs.72.

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Reports on the topic "IGF1"

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Hansen, Peter J., and Zvi Roth. Use of Oocyte and Embryo Survival Factors to Enhance Fertility of Heat-stressed Dairy Cattle. United States Department of Agriculture, 2011. http://dx.doi.org/10.32747/2011.7697105.bard.

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The overall goal was to identify survival factors that can improve pregnancy success following insemination or embryo transfer in lactating dairy cows exposed to heat stress. First, we demonstrated that oocytes are actually damaged by elevated temperature in the summer. Then we tested two thermoprotective molecules for their effect on oocyte damage caused by heat shock. One molecule, ceramide was not thermoprptective. Another, insulin-like growth factor-1 (IGF) reduced the effects of heat shock on oocyte apoptosis and oocyte cleavage when added during maturation. We also used lactating cows ex
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Sumrejkanchanakij, Piyamas, Prasit Pavasant, and Tusanee Yongchaitrakul. The influence of collagen I on Insulin-like growth factor-I induced Osteopontin expression in human periodontal ligament fibroblasts. Chulalongkorn University, 2006. https://doi.org/10.58837/chula.res.2006.14.

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Extracellular matrix and growth factors are the crucial factors that regulate healing and regenerating process in human periodontal ligament (HPDL) cells. The purpose of this study was to examine the effects of type I collagen and insulin-like growth factor-I (IGF-I) on osteopontin (OPN) expression. The data showed that OPN expression was significantly decreased when cells were cultured on collagen-coated plates. Addition of IGF-I obviously induced OPN expression only in a collagen-coated condition, suggesting an attenuation effect of IGF-I on OPN expression inhibited by type I collagen. Cells
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Funkenstein, Bruria, and Cunming Duan. GH-IGF Axis in Sparus aurata: Possible Applications to Genetic Selection. United States Department of Agriculture, 2000. http://dx.doi.org/10.32747/2000.7580665.bard.

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Many factors affect growth rate in fish: environmental, nutritional, genetics and endogenous (physiological) factors. Endogenous control of growth is very complex and many hormone systems are involved. Nevertheless, it is well accepted that growth hormone (GH) plays a major role in stimulating somatic growth. Although it is now clear that most, if not all, components of the GH-IGF axis exist in fish, we are still far from understanding how fish grow. In our project we used as the experimental system a marine fish, the gilthead sea bream (Sparus aurata), which inhabits lagoons along the Mediter
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Harbeson, Caroline E., and Steven A. Rosenzweig. The Role of Insulin-Like Growth Factor (IGF) in IGF-Mediated Tumorigenesis. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada432027.

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Cullen, Kevin J. The Effect of DNA Methylation on IGF2 Expression. Defense Technical Information Center, 1998. http://dx.doi.org/10.21236/ada361324.

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Hansen, Peter J., and Amir Arav. Embryo transfer as a tool for improving fertility of heat-stressed dairy cattle. United States Department of Agriculture, 2007. http://dx.doi.org/10.32747/2007.7587730.bard.

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The overall objective of the current proposal is to develop procedures to improve the pregnancy rate achieved following transfer of fresh or cryopreserved embryos produced in the laboratory into heat-stress recipients. The overall hypothesis is that pregnancy rate in heat-stressed lactating cows can be improved by use of embryo transfer and that additional gains in pregnancy rate can be achieved through development of procedures to cryopreserve embryos, select embryos most likely to establish and maintain pregnancy after transfer, and to enhance embryo competence for post-transfer survival thr
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Agura-Collins, Tanya D. Relationships Between IGF-1, IGF-Binding Proteins and Diet in African American and Caucasian Men. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada393886.

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Agurs-Collins, Tanya. Relationships Between IGF-1, IGF-Binding Proteins and Diet in African American and Caucasian Men. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada406111.

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Agurs-Collins, Tanya. Relationships Between IGF-1, IGF-Binding Proteins and Diet in African American and Caucasian Men. Defense Technical Information Center, 2004. http://dx.doi.org/10.21236/ada428675.

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Agurs-Collins, Tanya. Relationships Between IGF-1, IGF-Binding Proteins and Diet in African American and Caucasian Men. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada416702.

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