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1

Messina, Antonietta, Eléanor Luce, Nassima Benzoubir, et al. "Evidence of Adult Features and Functions of Hepatocytes Differentiated from Human Induced Pluripotent Stem Cells and Self-Organized as Organoids." Cells 11, no. 3 (2022): 537. http://dx.doi.org/10.3390/cells11030537.

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Background: Human-induced pluripotent stem cell-derived hepatocytes (iHeps) have been shown to have considerable potential in liver diseases, toxicity, and pharmacological studies. However, there is a growing need to obtain iHeps that are truly similar to primary adult hepatocytes in terms of morphological features and functions. We generated such human iHeps, self-assembled as organoids (iHep-Orgs). Methods: iPSC-derived hepatoblasts were self-assembled into spheroids and differentiated into mature hepatocytes modulating final step of differentiation. Results: In about four weeks of culture,
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2

Ageyev, A. I., S. S. Kozub, K. P. Myznikov, et al. "Superconducting program at IHEP." IEEE Transactions on Appiled Superconductivity 10, no. 1 (2000): 1556–59. http://dx.doi.org/10.1109/77.828540.

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3

Mochalov, V. "Spin physics at IHEP." Physics of Particles and Nuclei 44, no. 6 (2013): 930–36. http://dx.doi.org/10.1134/s1063779613060154.

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4

Klimenko, S. V., V. N. Kochin, and A. V. Samarin. "Computer graphics at IHEP." Computers & Graphics 10, no. 1 (1986): 63–69. http://dx.doi.org/10.1016/0097-8493(86)90069-5.

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5

Afonin, A. G., V. T. Baranov, S. Bellucci, et al. "Crystal undulator experiment at IHEP." Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms 234, no. 1-2 (2005): 122–27. http://dx.doi.org/10.1016/j.nimb.2004.11.006.

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6

Peng, Jun, Tao Huang, Hua-Chang Liu, et al. "Beam halo experiment at IHEP." Chinese Physics C 37, no. 3 (2013): 037002. http://dx.doi.org/10.1088/1674-1137/37/3/037002.

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7

Wu, Zhi-Tao, Dan Yao, Shu-Yi Ji, et al. "Optimized Hepatocyte-Like Cells with Functional Drug Transporters Directly-Reprogrammed from Mouse Fibroblasts and their Potential in Drug Disposition and Toxicology." Cellular Physiology and Biochemistry 38, no. 5 (2016): 1815–30. http://dx.doi.org/10.1159/000443120.

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Background/Aims: To develop a suitable hepatocyte-like cell model that could be a substitute for primary hepatocytes with essential transporter expression and functions. Induced hepatocyte-like (iHep) cells directly reprogrammed from mice fibroblast cells were fully characterized. Methods: Naïve iHep cells were transfected with nuclear hepatocyte factor 4 alpha (Hnf4α) and treated with selected small molecules. Sandwich cultured configuration was applied. The mRNA and protein expression of transporters were determined by Real Time PCR and confocal. The functional transporters were estimated by
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8

Movshovich, Ya V., A. V. Kuleshov, A. E. Burdonov, and Yu V. Novikov. "Irkutsk heavy engineering plant experience in the market of mining and processing equipment." Earth sciences and subsoil use 46, no. 1 (2023): 125–36. http://dx.doi.org/10.21285/2686-9993-2023-46-1-125-136.

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The article celebrates the 115th anniversary of the Irkutsk heavy engineering plant (IHEP) and describes its operation experience. During this time, IHEP worked its way up from a workshop supplying the army, an agricultural and mechanical plant to one of the largest Russian machine-building plants with a full production cycle in the Commonwealth of Independent States. The scientific base developed at the enterprise makes it possible to automate the same type tasks, as well as to upgrade equipment in order to improve its technological performance. The article analyzes the operation results of t
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9

Nechaevskiy, Andrey, Gennady Ososkov, Darya Pryahina, Vladimir Trofimov, and Weidong Li. "Simulation approach for improving the computing network topology and performance of the China IHEP Data Center." EPJ Web of Conferences 214 (2019): 08018. http://dx.doi.org/10.1051/epjconf/201921408018.

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The paper describes the project intended to improve the computing network topology and performance of the China IHEP Data Center taking into account growing numbers of hosts, experiments and computing resources. The analysis of the computing performance of the IHEP Data Center in order to optimize its distributed data processing system is a really hard problem due to the great scale and complexity of shared computing and storage resources between various HEP experiments. In order to fulfil the requirements, we adopt the simulation program SyMSim that was developed at the Laboratory of Informat
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10

Antipov, Yu, A. Borisov, V. Goryachev, et al. "IHEP drift tube prototype for ATLAS." Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 379, no. 3 (1996): 427–28. http://dx.doi.org/10.1016/0168-9002(96)00554-2.

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11

Valdiviezo, Alan, Yuki Kato, Erin S. Baker, Weihsueh A. Chiu, and Ivan Rusyn. "Evaluation of Metabolism of a Defined Pesticide Mixture through Multiple In Vitro Liver Models." Toxics 10, no. 10 (2022): 566. http://dx.doi.org/10.3390/toxics10100566.

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The evaluation of exposure to multiple contaminants in a mixture presents a number of challenges. For example, the characterization of chemical metabolism in a mixture setting remains a research area with critical knowledge gaps. Studies of chemical metabolism typically utilize suspension cultures of primary human hepatocytes; however, this model is not suitable for studies of more extended exposures and donor-to-donor variability in a metabolic capacity is unavoidable. To address this issue, we utilized several in vitro models based on human-induced pluripotent stem cell (iPSC)-derived hepato
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12

Wang, J. "The experimental program at IHEP of CAS." Journal of Instrumentation 15, no. 09 (2020): C09008. http://dx.doi.org/10.1088/1748-0221/15/09/c09008.

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13

Denisov, S. P., and D. A. Stoyanova. "Cherenkov counters in experiments at IHEP accelerator." Radiation Physics and Chemistry 75, no. 8 (2006): 856–61. http://dx.doi.org/10.1016/j.radphyschem.2005.12.009.

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14

Gao, J., and J. L. Xie. "Rf gun development at IHEP for BFELP." Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 304, no. 1-3 (1991): 357–63. http://dx.doi.org/10.1016/0168-9002(91)90886-u.

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15

Buzulutskov, A. F., and L. K. Turchanovich. "Development of photosensitive wire detectors at IHEP." Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 323, no. 1-2 (1992): 458–65. http://dx.doi.org/10.1016/0168-9002(92)90333-y.

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16

Zeng, Shan, Fazhi Qi, Lei Han, Xiangyu Gong, and Tao Wu. "Research and Evaluation of RoCE in IHEP Data Center." EPJ Web of Conferences 251 (2021): 02018. http://dx.doi.org/10.1051/epjconf/202125102018.

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With more and more large-scale scientific facilities are built, more and more HPC requirements are needed in IHEP. RDMA is a technology that allows servers in a network to exchange data in main memory without involving the processor, cache or operating system of either server, which can provide high bandwidth and low latency. There are two RDMA technologies which were InfiniBand and a relative newcomer called RoCE – RDMA over Converged Ethernet. This paper introduces the RoCE technology, we research and compare the performance of both IB and RoCE in IHEP data center, and we also evaluate the a
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17

Zhou, Z. S., Y. Chen, Y. L. Chi, et al. "Progress on CEPC 650 MHz klystron." International Journal of Modern Physics A 36, no. 22 (2021): 2142011. http://dx.doi.org/10.1142/s0217751x21420112.

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The beam power of the CEPC Collider is about 60 MW, so an efficiency of an RF power source is very important for cost of project implementation. The most popular source for an accelerator is a klystron, which has the advantage that it can be operated at high power with a reasonable high efficiency. IHEP is developing 650 MHz klystron with 800 kW CW output power and 80% efficiency. To reach this goal, a couple of klystron prototypes will be manufactured in the near future. The first prototype is completely manufactured by Institute of Electronics (IE) and GLVAC Company and the first step of hig
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18

Liu, Baiqi, Peng Sha, Chao Dong, et al. "Nitrogen doping with dual-vacuum furnace at IHEP." Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 993 (March 2021): 165080. http://dx.doi.org/10.1016/j.nima.2021.165080.

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19

Alekseev, A. G., and S. A. Kharlampiev. "Dosimetric Characteristics of the IHEP Neutron Reference Fields." Radiation Protection Dosimetry 70, no. 1 (1997): 341–44. http://dx.doi.org/10.1093/oxfordjournals.rpd.a031972.

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20

Abramov, V. V., N. I. Belikov, Yu M. Goncharenko, et al. "Preparation of new polarization experiment SPASCHARM at IHEP." Journal of Physics: Conference Series 295 (May 1, 2011): 012018. http://dx.doi.org/10.1088/1742-6596/295/1/012018.

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21

AFONIN, A. G., V. T. BARANOV, G. I. BRITVICH, et al. "STUDIES AND APPLICATION OF BENT CRYSTALS FOR BEAM STEERING AT 70 GEV IHEP ACCELERATOR." International Journal of Modern Physics A 25, supp01 (2010): 86–97. http://dx.doi.org/10.1142/s0217751x10049931.

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This report overviews studies accomplished in the U70 proton synchrotron of IHEP-Protvino during the recent two decades. Major attention is paid to a routine application of bent crystals for beam extraction from the machine. It has been confirmed experimentally that efficiency of beam extraction with a crystal deflector of around 85% is well feasible for a proton beam with intensity up to 1012 protons per cycle. Another trend is to use bent crystals for halo collimation in a high energy collider. New promising options emerge for, say, LHC and ILC based on the "volume reflection" effect, which
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22

Xu, Hang, Jinqiang Xu, Xiaoping Li, Liwen Feng, Senlin Huang, and Jingyi Li. "High power drive laser system for photocathode at IHEP." Optics Express 29, no. 18 (2021): 29550. http://dx.doi.org/10.1364/oe.438199.

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23

Zian, ZHU, ZHAO Ling, HOU Zhilong, et al. "Development of Superconducting Magnets and its Applications in IHEP." TEION KOGAKU (Journal of Cryogenics and Superconductivity Society of Japan) 46, no. 11 (2011): 635–40. http://dx.doi.org/10.2221/jcsj.46.635.

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24

Chesnokov, Yu A., A. G. Afonin, V. T. Baranov, et al. "Crystal devices for beam steering in the IHEP accelerator." Journal of Physics: Conference Series 517 (May 30, 2014): 012042. http://dx.doi.org/10.1088/1742-6596/517/1/012042.

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25

Nurushev, S. B., M. A. Chetvertkov, V. A. Chetvertkova, et al. "Polarized antiproton beam at U-70 accelerator of IHEP." Journal of Physics: Conference Series 678 (February 5, 2016): 012047. http://dx.doi.org/10.1088/1742-6596/678/1/012047.

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26

Weichao Yao, Zi'an Zhu, Ling Zhao, et al. "Uniformity Aspects of Superconducting MRI Magnet Developed by IHEP." IEEE Transactions on Applied Superconductivity 24, no. 1 (2014): 30–34. http://dx.doi.org/10.1109/tasc.2013.2287314.

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27

JIANG, Xiaowei, Jingyan Shi, Jiaheng Zou, Qingbao Hu, Ran Du, and Zhenyu Sun. "Research and Exploit of Resource Sharing Strategy at IHEP." EPJ Web of Conferences 214 (2019): 03014. http://dx.doi.org/10.1051/epjconf/201921403014.

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At IHEP (Institute of High Energy Physics, Chinese Academy of Sciences), computing resources are contributed by different experiments including BES, JUNO, DYW, HXMT, etc. The resources were divided into different partitions to satisfy the dedicated experiment data processing requirements. IHEP had a local Torqu&Maui cluster with 50 queues serving for above 10 experiments. The separated resource partitions leaded to imbalance resource load. In a typical situation, BES resource partition was quite busy without free slot but still with lots of jobs in idle, while JUNO resources are free and w
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28

Sytin, A. "Present status of the UNK control system at IHEP." Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 352, no. 1-2 (1994): 56–60. http://dx.doi.org/10.1016/0168-9002(94)91460-5.

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29

Gao, Jie, JiYuan Zhai, WeiMin Pan, et al. "Status of the IHEP 1.3 GHz superconducting RF program." Science China Physics, Mechanics and Astronomy 54, S2 (2011): 154–59. http://dx.doi.org/10.1007/s11433-011-4510-y.

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30

Jiang, Xiaowei, Chaoqi Guo, Qingbao Hu, Ran Du, Jingyan Shi, and Gongxing Sun. "Using Kerberos Tokens in Distributed Computing System at IHEP." EPJ Web of Conferences 295 (2024): 04052. http://dx.doi.org/10.1051/epjconf/202429504052.

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The token-based certification method is spreading in the distributed computing system of high energy physics. More and more software and middleware are supporting tokens as one of the certification methods. As an example, WLCG has upgraded all the services to support WLCG tokens [1]. In IHEP (Institute of High Energy Physics in China), the Kerberos [2] token has been used as the main certification method in the local cluster. Naturally, it is selected as the certification method in the distributed computing system. In this case, a set of toolkits were developed or introduced to use Kerberos to
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31

Yuan, C. Z. "The initial ψ′ physics program at the BES experiment". Modern Physics Letters A 35, № 24 (2020): 2030009. http://dx.doi.org/10.1142/s0217732320300098.

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In this article, I review the early years of the study of charmonium physics at the BES experiment and its consequences on the future research at the BESII and BESIII experiments, based on my own experience of working at BES since summer 1992 and material found from the Institute of High Energy Physics (IHEP) archives.
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32

Li, M., Y. Fan, B. Liu, et al. "The performance of IHEP-NDL LGAD sensors after neutron irradiation." Journal of Instrumentation 16, no. 08 (2021): P08053. http://dx.doi.org/10.1088/1748-0221/16/08/p08053.

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33

Masuzawa, M., and R. Sugahara. "Field Measurements of the ATF2 Quadrupole Magnets Manufactured by IHEP." IEEE Transactions on Applied Superconductivity 20, no. 3 (2010): 1969–72. http://dx.doi.org/10.1109/tasc.2010.2041763.

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34

Borisov, A., R. Fakhroutdinov, A. Kojine, et al. "ATLAS monitored drift tube assembly and test at IHEP (Protvino)." Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 494, no. 1-3 (2002): 214–17. http://dx.doi.org/10.1016/s0168-9002(02)01468-7.

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35

Peng, Ying-Hua, Xin-Yin Zhang, Han Li, Peng Sha, Zhong-Quan Li, and Wei-Min Pan. "Design of a 325 MHz SC Spoke040 cavity at IHEP." Chinese Physics C 38, no. 11 (2014): 117005. http://dx.doi.org/10.1088/1674-1137/38/11/117005.

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36

Prokoshkin, Yu D. "Cherenkov detectors in experiments at the IHEP 70 GeV accelerator." Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 248, no. 1 (1986): 60–61. http://dx.doi.org/10.1016/0168-9002(86)90497-3.

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37

Baranov, S., Y. Batusov, S. Bunyatov, et al. "Search for heavy neutrinos at the IHEP-JINR Neutrino Detector." Physics Letters B 302, no. 2-3 (1993): 336–40. http://dx.doi.org/10.1016/0370-2693(93)90405-7.

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38

Du, Ran, Jingyan Shi, Xiaowei Jiang, and Chaoqi Guo. "A web workbench system for the Slurm cluster at IHEP." EPJ Web of Conferences 295 (2024): 01007. http://dx.doi.org/10.1051/epjconf/202429501007.

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Slurm REST APIs are released since version 20.02. With those REST APIs one can interact with slurmctld and slurmdbd daemons in a REST- ful way. As a result, job submission and cluster status query can be achieved with a web system. To take advantage of Slurm REST APIs, a web workbench system is developed for the Slurm cluster at IHEP. The workbench system con- sists with four subsystems including dashboard, tomato, jasmine and cosmos. The dashboard subsystem is used to display cluster status including nodes and jobs. The tomato subsystem is developed to submit special HTCondor glidein jobs in
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39

Donskov, Sergey V., Vladimir N. Kolosov, Anatoly A. Lednev та ін. "A search for decay η′ → 4 π0 with GAMS-4π setup". Modern Physics Letters A 29, № 40 (2014): 1450213. http://dx.doi.org/10.1142/s0217732314502137.

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A search for rare decay η′ → 4 π0 has been performed with GAMS-4π setup. The new upper limit is BR (η′ → 4 π0) < 3.2 ⋅10-4 at 90% confidence level. The π- p charge-exchange reaction at 32.5 GeV /c was used as a source of 1.3⋅106η′ mesons. Experiment was carried out at the IHEP U-70 accelerator.
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40

Dong, Chao, Zefeng Lin, Peng Sha, Baiqi Liu, Lingxi Ye, and Xiangcong He. "Preliminary Research of Niobium Cavity Coating with Nb3Sn Film at IHEP." Physica C: Superconductivity and its Applications 600 (September 2022): 1354107. http://dx.doi.org/10.1016/j.physc.2022.1354107.

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41

Rykov, V. L., V. V. Abramov, A. A. Bogdanov, et al. "Polarimetry with inclusive charged pions at U-70 accelerator of IHEP." Journal of Physics: Conference Series 678 (February 5, 2016): 012028. http://dx.doi.org/10.1088/1742-6596/678/1/012028.

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42

Qian, S., Y. Wang, Z. Ning, et al. "The high timing resolution T0 system in IHEP E3 beam line." Journal of Instrumentation 7, no. 02 (2012): P02013. http://dx.doi.org/10.1088/1748-0221/7/02/p02013.

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43

Bao-Yi, Wang, Ma Yan-Yun, Wang Ping, et al. "Development and application of the intense slow positron beam at IHEP." Chinese Physics C 32, no. 2 (2008): 156–59. http://dx.doi.org/10.1088/1674-1137/32/2/016.

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Zu-Sheng, Zhou, Chi Yun-Long, Git Meng-Ping, and Pei Guo-Xi. "200 MW S-band traveling wave resonant ring development at IHEP." Chinese Physics C 34, no. 3 (2010): 402–4. http://dx.doi.org/10.1088/1674-1137/34/3/019.

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Wang, Shu-Hong, Jiu-Qing Wang, Sen-Yu Chen, et al. "Design studies on the ERL-FEL test facility at IHEP, Beijing." Chinese Physics C 36, no. 5 (2012): 469–74. http://dx.doi.org/10.1088/1674-1137/36/5/016.

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46

Bogdanov, A. A., M. A. Chetvertkov, V. A. Chetvertkova, et al. "Beam polarimetry at the SPASCHARM experiment at IHEP U-70 accelerator." Journal of Physics: Conference Series 798 (January 2017): 012179. http://dx.doi.org/10.1088/1742-6596/798/1/012179.

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47

Avdeichikov, V. V., A. N. Aleev, E. N. Ardashev, et al. "Spectrometer with a vertex detector for experiments at the IHEP accelerator." Instruments and Experimental Techniques 56, no. 1 (2013): 9–31. http://dx.doi.org/10.1134/s0020441212060012.

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48

Shalanda, N. A., M. M. Soldatov, and V. A. Senko. "Data taking from multiwire chambers and hodoscopes at IHEP physical setups." Instruments and Experimental Techniques 59, no. 2 (2016): 209–15. http://dx.doi.org/10.1134/s0020441216010139.

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49

Voight, Mamie, and Julie Ajinkya. "An IHEP Perspective: Research to Inform Community College Policy and Practice." Community College Journal of Research and Practice 39, no. 10 (2015): 923–28. http://dx.doi.org/10.1080/10668926.2015.1033784.

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50

Afonin, A. G., V. T. Baranov, V. M. Biryukov, et al. "The schemes of proton extraction from IHEP accelerator using bent crystals." Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms 234, no. 1-2 (2005): 14–22. http://dx.doi.org/10.1016/j.nimb.2004.12.128.

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