Academic literature on the topic 'IL-10'

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Journal articles on the topic "IL-10"

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Commins, Scott, John W. Steinke, and Larry Borish. "The extended IL-10 superfamily: IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, IL-28, and IL-29." Journal of Allergy and Clinical Immunology 121, no. 5 (2008): 1108–11. http://dx.doi.org/10.1016/j.jaci.2008.02.026.

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Glocker, Erik-Oliver, Daniel Kotlarz, Christoph Klein, Neil Shah, and Bodo Grimbacher. "IL-10 and IL-10 receptor defects in humans." Annals of the New York Academy of Sciences 1246, no. 1 (2011): 102–7. http://dx.doi.org/10.1111/j.1749-6632.2011.06339.x.

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Wang, Min, Youji Hu, Ischiro Shima, and Mark E. Stearns. "IL-10/IL-10 Receptor Signaling Regulates TIMP-1 Expression." Cancer Biology & Therapy 1, no. 5 (2002): 556–63. http://dx.doi.org/10.4161/cbt.1.5.222.

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Rennick, Donna M., and Madeline M. Fort. "XII. IL-10-deficient (IL-10−/−) mice and intestinal inflammation." American Journal of Physiology-Gastrointestinal and Liver Physiology 278, no. 6 (2000): G829—G833. http://dx.doi.org/10.1152/ajpgi.2000.278.6.g829.

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Interleukin (IL)-10−/−mice spontaneously develop intestinal inflammation characterized by discontinuous transmural lesions affecting the small and large intestine and by dysregulated production of proinflammatory cytokines. The uncontrolled generation of IFN-γ-producing CD4+T cells (Th1 type) has been shown to play a causal role in the development of enterocolitis affecting these mutants. This article discusses studies of IL-10−/−mice that have investigated the role of enteric organisms in triggering intestinal disease, the mediators responsible for initiating and maintaining intestinal diseas
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Jankovic, Dragana, and Giorgio Trinchieri. "IL-10 or not IL-10: that is the question." Nature Immunology 8, no. 12 (2007): 1281–83. http://dx.doi.org/10.1038/ni1207-1281.

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Mittal, Sharad K., Kyung-Jin Cho, Satoshi Ishido, and Paul A. Roche. "Interleukin 10 (IL-10)-mediated Immunosuppression." Journal of Biological Chemistry 290, no. 45 (2015): 27158–67. http://dx.doi.org/10.1074/jbc.m115.682708.

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Ouyang, Wenjun, and Anne O’Garra. "IL-10 Family Cytokines IL-10 and IL-22: from Basic Science to Clinical Translation." Immunity 50, no. 4 (2019): 871–91. http://dx.doi.org/10.1016/j.immuni.2019.03.020.

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Conti, P., D. Kempuraj, S. Frydas, et al. "IL-10 subfamily members: IL-19, IL-20, IL-22, IL-24 and IL-26." Immunology Letters 88, no. 3 (2003): 171–74. http://dx.doi.org/10.1016/s0165-2478(03)00087-7.

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Murray, Henry W., Christina M. Lu, Smita Mauze, et al. "Interleukin-10 (IL-10) in Experimental Visceral Leishmaniasis and IL-10 Receptor Blockade as Immunotherapy." Infection and Immunity 70, no. 11 (2002): 6284–93. http://dx.doi.org/10.1128/iai.70.11.6284-6293.2002.

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ABSTRACT Interleukin-10 (IL-10) is thought to promote intracellular infection, including human visceral leishmaniasis, by disabling Th1 cell-type responses and/or deactivating parasitized tissue macrophages. To develop a rationale for IL-10 inhibition as treatment in visceral infection, Th1 cytokine-driven responses were characterized in Leishmania donovani-infected BALB/c mice in which IL-10 was absent or overexpressed or its receptor (IL-10R) was blockaded. IL-10 knockout and normal mice treated prophylactically with anti-IL-10R demonstrated accelerated granuloma assembly and rapid parasite
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Asadullah, K., K. Stephanek, M. Leupold, et al. "Relative IL-10 deficiency and effects of IL-10 therapy in psoriasis." Journal of Dermatological Science 16 (March 1998): S30. http://dx.doi.org/10.1016/s0923-1811(98)83173-3.

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Dissertations / Theses on the topic "IL-10"

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Frisch, Kristina. "Klonierung von IL-10 und IL-10-Homologen und Funktionsanalyse in einem Mausmodell der polymikrobiellen Sepsis." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=973392185.

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Ng, Tien Haeng Sky. "Mechanisms of IL-10 transcriptional regulation." Thesis, University of Bristol, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.702135.

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Previous work has shown that subcutaneous (s.c) specific immunotherapy (SIT) using the myelin protein peptide MBP Acl-9 [4Y] induces protection against EAE in the TCR transgenic Tg4 mice. Repeated administration of MBP Ac1-9 [4Y] was found to induce IL-1O expressing TH1 like cells which were termed IL-l0 Tregs. To further the understanding of how IL-1O transcription is regulated, the expression of IFN-y, IL-4, IL-1O, c-Maf, NFIL3 protein and mRNA, Gata3 mRNA and epigenetic modifications at the Il10 promoter were characterised for each dose of s.c MBP Ac 1-9 [4 Y] administration. The analysis r
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Cordeiro, Cynthia Azeredo. "Polimorfismos dos Genes das Citocinas IL-1alfa, IL -1beta, IL-10 e TNF-alfa." Universidade Federal de Minas Gerais, 2008. http://hdl.handle.net/1843/RRSA-7F5KG7.

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Purpose: Toxoplasmic Retinochoroiditis (TR) is the most common identifiable cause of posterior uveitis in many parts of the world. There is a great controversy regarding which factors are responsible for the occurrence or reccurrence of TR. Experimental data have demonstrated a relevant role for IL-10, TNF-alfa, IL-1alfa and IL-1alfa in the modulation of acute ocular toxoplasmosis. Therefore, we aim to investigate thepossible association between an IL10 (-1082G/A), TNF-alfa (-308G/A), IL1A (-889C/T) and IL1B (+3954C/T) gene polymorphisms and TR in humans. Methods: One hundred patients with dia
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Wong, Li-Chuen. "IL-10 promoter polymorphisms in atopic dermatitis." Thesis, The University of Sydney, 2002. https://hdl.handle.net/2123/27849.

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Atopic dermatitis (AD) is one of the many clinical manifestations of atopy. It is one of the most common chronic inflammatory skin diseases with increasing prevalence over the last century. The aetiology of this disease is multifactorial with a complex interaction of genetic, environmental and immunologic factors.
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Saramago, Eduardo Alves. "O hidrogênio molecular potencializa a hipotermia e previne a hipotensão e a febre durante a inflamação sistêmica induzida por LPS." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/17/17134/tde-07022019-140036/.

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O hidrogênio molecular (H2) exerce efeito antioxidante, anti-apoptótico e antiinflamatório. Nesse estudo testamos a hipótese que o H2 modula as mudanças cardiovasculares, inflamatórias e termorregulatórias na inflamação sistêmica (IS) induzida por lipopolissacarídeo (LPS) em diferentes doses (0,1 ou 1,5 mg/kg, intravenoso, induzindo IS moderada ou severa) em ratos machos Wistar (250-300 g). LPS ou salina foi injetada imediatamente antes do início dos 360 minutos de inalação do H2 (2% H2, 21% O2, balanceado com nitrogênio) ou ar ambiente (21% O2, balanceado com nitrogênio). A temperatura corpor
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Vale, Mariana Lima. "Atividade analgesica das interleucinas 4, 10 e 13 (IL-4, IL-10 e il-13) na dor inflamatoria experimental : papel de celulas residentes e citocinas." reponame:Repositório Institucional da UFC, 2000. http://www.repositorio.ufc.br/handle/riufc/2569.

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VALE, Mariana Lima. Atividade analgesica das interleucinas 4, 10 e 13 (IL-4, IL-10 e il-13) na dor inflamatoria experimental : papel de celulas residentes e citocinas. 2000. 140 f. Dissertação (Mestrado em Farmacologia) - Universidade Federal do Ceará. Faculdade de Medicina, 2000.<br>Submitted by denise santos (denise.santos@ufc.br) on 2012-05-04T12:19:28Z No. of bitstreams: 1 2000_dis_mlvale.pdf: 664941 bytes, checksum: a8df00b6a53f2d6632ebe816657800aa (MD5)<br>Approved for entry into archive by Eliene Nascimento(elienegvn@hotmail.com) on 2012-05-04T12:36:24Z (GMT) No. of bitstreams: 1 2000_
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Costa, Tânia Alves da. "A função da IL-10 na paracoccidioidomise pulmonar murina." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/42/42133/tde-16122010-113911/.

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O principal mecanismo de defesa de hospedeiros infectados pelo Paracoccidioides brasiliensis (Pb), fungo dimórfico que causa a mais importante micose sistêmica da América Latina, é a imunidade celular. Neste processo participam macrófagos ativados por IFN-<font face=\"Symbol\">g e a IL-10 parece ser a citocina que se contrapõe a esta ativação. Tanto na patologia humana como em modelos experimentais há fortes indicações de que a IL-10 age como supressora da imunidade celular causando efeitos deletérios aos hospedeiros; entretanto, estudos diretos sobre a função da IL-10 na paracoccidiodomicose
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Cirocco, Robert E. "Cytokine analisys in atlantic bottlenose dolphins: molecular characterization of IL-4, IL-6, and IL-10." FIU Digital Commons, 2001. http://digitalcommons.fiu.edu/etd/2370.

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The health status of wild and captive Atlantic Bottlenose dolphins (Tersiops truncatis) is difficult to ascertain. Mass strandings of these animals have been attributed to pollutants, as well as bacterial infections. Using human Enzyme Linked Immuno-Assays (ELISA) for immunological cytokines, I measured soluble cytokine levels with respect to their health status. In a retrospective analysis of dolphin sera, there was a trend of higher cytokine levels in “sick” animals. I cultured dolphin lymphocytes in the presence of a mitogen (PHA), a super antigen (Staph-A), Lipopolysaccharide (LPS), and a
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Mitchell, Ruth Elizabeth. "Regulation of IL-10 in CD4+ T cells." Thesis, University of Bristol, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.691167.

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OLIVEIRA, Gabriela Almeida de. "Polimorfismos de citocinas (TNF-A, IL-10 e IL-17) no câncer gástrico." Universidade Federal do Pará, 2016. http://repositorio.ufpa.br/jspui/handle/2011/7251.

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Submitted by Cássio da Cruz Nogueira (cassionogueirakk@gmail.com) on 2017-01-05T11:27:08Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissertacao_PoliformismosCitocinasCancer.pdf: 4538726 bytes, checksum: a9402888128957139063bdb3b7fd849e (MD5)<br>Approved for entry into archive by Edisangela Bastos (edisangela@ufpa.br) on 2017-01-09T17:13:32Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissertacao_PoliformismosCitocinasCancer.pdf: 4538726 bytes, checksum: a9402888128957139063bdb3b7fd849e
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Books on the topic "IL-10"

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Grossi, Plinio. Il Ticino dei '10. Fontana, 1997.

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Gordon, Yefim. Ilyushin IL-2 and IL-10 Shturmovik. Crowood, 2004.

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Costa, Manuel Rui. Il mio 10 per Firenze. AN.MA & San Marco Sport Events, 1998.

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Mübariz, Qurbanlı, and Ălii̐ev Ilgar, eds. Yeni Azärbaycan Partiyası 10 il. Azarbaycan, 2002.

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Chiara, Piero. Il Decameron raccontato in 10 novelle. A. Mondadori, 1992.

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Castel nuovo (Museum : Naples, Italy), ed. Il Futurismo: Anni '10 - anni '20. Skira, 2018.

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Paek, Tʻae-wŏn. Paek Tʻae-wŏn kongye chakpʻumjŏn: 1985-yŏn 10-wŏl 10-il--16-il Tongbang Pʻŭllaja Misulgwan. Kabŭl, 1985.

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Kim, Chŏng-il. Misullon: 1991-yŏn 10-wŏl 16-il. Chosŏn Nodongdang Chʻulpʻansa, 1992.

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Kim, Chŏng-il. Misullon: 1991-yŏn 10-wŏl 16-il. Chosŏn Nodongdang Chʻulpʻansa, 1992.

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Caflisch, Ulrich. Il gi X: Giug humoristic en 10 scenas. Lia Rumantscha, 1993.

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Book chapters on the topic "IL-10"

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Benjamin, David. "Interleukin-10 (IL-10)." In Cytokines: Interleukins and Their Receptors. Springer US, 1995. http://dx.doi.org/10.1007/978-1-4613-1241-3_12.

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Engelhardt, Karin R., and Bodo Grimbacher. "IL-10 in Humans: Lessons from the Gut, IL-10/IL-10 Receptor Deficiencies, and IL-10 Polymorphisms." In Current Topics in Microbiology and Immunology. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-662-43492-5_1.

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Lee, Myung-Shik, and Nora Sarvetnick. "IL-10 Transgenic Mice." In Interleukin-10. Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-662-22038-2_15.

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Shanmugam, Saravanan, Jullyana S. S. Quintans, Parimelazhagan Thangaraj, et al. "Monoterpenes Modulating IL-10." In Phytomedicine. CRC Press, 2020. http://dx.doi.org/10.1201/9781003014898-16.

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Carvalho, Edgar M. "IL-10 In Human Leishmaniasis." In Interleukin-10. Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-662-22038-2_10.

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Sieling, Peter A., and Robert L. Modlin. "IL-10 in Mycobacterial Infection." In Interleukin-10. Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-662-22038-2_9.

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Schroeder, John T. "Diagnostic Components: T Helper Cell Cytokines (IL-4, IL-5, IL-9, IL-10, IL-13, IL-17)." In Encyclopedia of Medical Immunology. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4614-9194-1_298.

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Schuitemaker, Hanneke, Neeltje A. Kootstra, and Frank Miedema. "IL-10 and HIV-1 Replication." In Interleukin-10. Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-662-22038-2_11.

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Yssel, Hans, and René de Waal Malefyt. "IL-10 and Human T Cells." In Interleukin-10. Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-662-22038-2_3.

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Van Vlasselaer, Peter. "IL-10 and Bone Formation/Hematopoiesis." In Interleukin-10. Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-662-22038-2_7.

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Conference papers on the topic "IL-10"

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Sato, Yoichi, Arvydas Kausas, and Takunori Taira. "Improved effective thermal conductivity of DFC-PowerChip fabricated by il-SAB." In Advanced Solid State Lasers. Optica Publishing Group, 2024. https://doi.org/10.1364/assl.2024.aw5a.3.

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Thermal resistance between bonded surfaces in composite media fabricated by inter-layer surface activated bonding (il-SAB) is negligible. It indicates 10-W/mK thermal conductivity of YAG can be enhanced over 27.9-W/mK using DFC-PowerChip by il-SAB.
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"Транскриптомный ответ Lacticaseibacillus rhamnosus на цитокины IL-8 и IL-10". У Биоинформатика регуляции и структуры геномов / системная биология. ИЦиГ СО РАН, 2024. http://dx.doi.org/10.18699/bgrs2024-1.4-09.

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Darmaputra, I. Gusti Nyoman, Luh Mas Rusyati, Wibi Riawan, Anang Endaryanto, and Cita Rosita Sigit Prakoeswa. "The Correlation between Neutrophil CD64, Interleukin-17 (Il-17), Interleukin-10 (Il-10) in Skin Tissue and Neutrophil CD64, Il-17 and Il-10 in Blood Circulation in Erythema Nodosum Leprosum (ENL) Patients." In The 23rd Regional Conference of Dermatology 2018. SCITEPRESS - Science and Technology Publications, 2018. http://dx.doi.org/10.5220/0008155802860290.

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Khan, Aslam A. "Abstract 387: PEDF binds to IL- 10 receptor in the absence of IL-10 and inhibits melanoma tumor growth." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-387.

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Gollnick, Sandra O., David A. Musser, and Barbara W. Henderson. "Photodynamic therapy affects the expression of IL-6 and IL-10 in vivo." In BiOS '98 International Biomedical Optics Symposium, edited by Steven L. Jacques. SPIE, 1998. http://dx.doi.org/10.1117/12.308168.

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Cerri, S., M. Gold, J. Jin, et al. "Human IL-10 Producing T Cells Specific forMycobacterium tuberculosis." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a5907.

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Boaventura, Thayssa Aparecida. "IL-10 NO MICROAMBIENTE TUMORAL: IMUNOSSUPRESSÃO OU ESTRATÉGIA TERAPÊUTICA?" In V Congresso Brasileiro de Imunologia. Revista Multidisciplinar em Saúde, 2025. https://doi.org/10.51161/v-conbrai/54318.

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Senturk, T., BG Cetin, and N. Aydin. "315 The relationship between il-10, il-17, il-23 and vitamin d levels, and disease activity of systemic lupus erythematosus." In LUPUS 2017 & ACA 2017, (12th International Congress on SLE &, 7th Asian Congress on Autoimmunity). Lupus Foundation of America, 2017. http://dx.doi.org/10.1136/lupus-2017-000215.315.

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Sato, K., Y. Aizaki, H. Yazawa, and T. Mimura. "AB0066 Combination of il-10 and il-18 but not il-6 and il-18 induces ifn-gamma production and surface expression of trail on nk cells." In Annual European Congress of Rheumatology, EULAR 2018, Amsterdam, 13–16 June 2018. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. http://dx.doi.org/10.1136/annrheumdis-2018-eular.3407.

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Cai, J., G. Su, X. Qi, et al. "Myeloid-Derived Suppressor Cells Ameliorate Lung Ischemia-Reperfusion Injury Via Regulation of IL-17 and IL-10." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1002.

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Reports on the topic "IL-10"

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Petkova, Boryana, Emilia Alova, Iliya Karagyozov, et al. IL-10: a Potential Prognostic Biomarker for Missed Abortion. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, 2019. http://dx.doi.org/10.7546/crabs.2019.07.16.

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Grigorov, Boncho G., Anastasiya G. Trenova, Georgi S. Slavov, Lyuba D. Miteva, and Spaska A. Stanilova. Interleukin‑10 (IL‑10) Promoter Polymorphism at Position –1082 in Bulgarian Patients with Multiple Sclerosis. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, 2019. http://dx.doi.org/10.7546/crabs.2019.01.11.

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Cao, Xianling, Xuanyou Zhou, Naixin Xu, Songchang Chang, and Chenming Xu. Association of IL-4 and IL-10 Polymorphisms with Preterm Birth Susceptibility: A Systematic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.4.0044.

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Review question / Objective: The aim of our systematic review and meta-analysis was to summarize the effects of IL-4 and IL-10 gene polymorphism and clarify their possible association with PTB. Condition being studied: World Health Organization (WHO) defines preterm birth (PTB) as babies born alive before 37 weeks of pregnancy are completed. The new estimates show that the prevalence of PTB during 2014 ranged from 8.7% to13.4% of all live births, about 15 million preterm babies born each year. Besides, PTB is the leading cause of death worldwide for children below 5 years of age. Babies born p
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สุรทัตต์, สันนิภา, та รุ่งโรจน์ ธนาวงษ์นุเวช. การศึกษาผลของไวรัสวัคซีน พี อาร์ อาร์ เอส ต่อการสร้างไซโตคายน์ ของเซลล์เม็ดเลือดขาวชนิดโมโนนิวเคลียร์ที่แยกได้จากสุกร : รายงานผลการวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 2004. https://doi.org/10.58837/chula.res.2004.82.

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งานวิจัยนี้ทำการศึกษาผลของเชื้อไวรัสวัคซีนพี อาร์ อาร์ เอส (In vitro effect) ต่อการสร้างไซโตคายน์ของเซลล์เม็ดเลือดขาวชนิดโมโนนิวเคลียร์ (PBMC) ที่แยกได้จากสุกร โดยทำการเพาะเลี้ยงเซลล์ PBMC ร่วมกับเชื้อไวรัสวัคซีนพี อาร์ อาร์ เอส ชนิดต่างๆ ในห้องปฏิบัติการณ์ ผลการศึกษาพบว่าเชื้อไวรัสวัคซีนพี อาร์ อาร์ เอส ชนิดสายพันธุ์ยุโรป (EU) สามารถกระตุ้นให้เซลล์ PBMC มีการสร้างสารอินเตอร์ลิวคิน 10 (IL-10) ซึ่งเป็นไซโตคายน์ที่มีฤทธิ์ในการกดการทำงานของระบบภูมิคุ้มกันสูงขึ้นกว่าปกติ โดยทำการยืนยันผลการศึกษาทั้งในระดับการแสดงออกของยีน และโปรตีน IL-10 ที่หลั่งออกมาจากเซลล์ โดยทั้งนี้ไม่พบการกระตุ้นการสร้าง IL-1
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Jafrin, Sarah, Md Abdul Aziz, and Mohammad Safiqul Islam. Elevated levels of pleiotropic interleukin-6 (IL-6) and interleukin-10 (IL-10) are critically involved with the severity and mortality of COVID-19: An updated longitudinal meta-analysis and systematic review on 147 studies. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.4.0046.

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Review question / Objective: How were serum IL-6 and IL-10 linked with the severity and mortality of COVID-19 patients? To evaluate the role of IL-6 and IL-10 in the development of the severity or morality of COVID-19 patients. The outcomes (mean difference) were calculated between the severe vs. non-severe COVID-19 patients and non-survival vs. survival patients to evaluate the risk of severity or mortality. Condition being studied: Severity and mortality among the COVID-19 patients. Information sources: The international scientific authorized databases such as Google Scholar, PubMed, Embase,
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ธนาวงษ์นุเวช, รุ่งโรจน์, та สันนิภา สุรทัตถ์. การศึกษาพยาธิกำเนิดของไวรัสพี อาร์ อาร์ เอส สายพันธุ์ที่แยกได้ในประเทศไทย : รายงานผลการวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 2003. https://doi.org/10.58837/chula.res.2003.66.

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ไวรัสพี อาร์ อาร์ เอส ที่แยกได้ในประเทศไทย ทั้ง 2 สายพันธุ์สามารถเหนี่ยวนำให้เกิดโรคได้โดยพบว่า ไวรัสพี อาร์ อาร์ เอส สายพันธุ์ US (01NP1) ก่อโรครุนแรงกว่า ไวรัสพี อาร์ อาร์ เอส สายพันธุ์ EU (02SB3) และยังพบรอยโรครุนแรงในสุกรที่ชันสูตรวันที่ 15 แต่พบแอนติเจนของไวรัส พี อาร์ อาร์ เอสในสุกรกลุ่มที่ได้รับเชื้อสายพันธุ์ยุโรปมากกว่าสายพันธุ์อเมริกา ในแทบทุกเนื้อเยื่อที่ได้รับการตรวจไวรัส พี อาร์ อาร์ เอส สายพันธุ์ EU อาจแฝงตัวในสุกรได้นานกว่าและอาจมีผลให้เกิดภาวะ persistent infection ทำให้ยากต่อการกำจัดเชื้อออกจากฝูงสุกร นอกจากนี้ยังพบการเพิ่มขึ้นของยีนที่สร้าง IL-10 อย่างมีนัยสำคัญทางสถิติ (p&lt;0
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Splitter, Gary, Zeev Trainin, and Yacov Brenner. Lymphocyte Response to Genetically Engineered Bovine Leukemia Virus Proteins in Persistently Lymphocytic Cattle from Israel and the U.S. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7570556.bard.

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The goal of this proposal was to identify proteins of BLV recognized by lymphocyte subpopulations and determine the contribution of these proteins to viral pathogenesis. Our hypothesis was that BLV pathogenesis is governed by the T-cell response and that the immune system likely plays an important role in controlling the utcome of infection. Our studies presented in ths final report demonstrate that T cell competency declines with advancing stages of infection. Dramatic differences were observed in lymphocyte proliferation to recombinant proteins encoded by BLV gag (p12, p15, and p24) and env
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ธราภิวัฒนานนท์, ทิพวรรณ, ประสิทธิ์ ภวสันต์ та ทัศนีย์ ยงชัยตระกูล. การตอบสนองของเซลล์โพรงฟันต่ออินเตอร์ลิวคิน-6 : รายงานวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 2007. https://doi.org/10.58837/chula.res.2007.16.

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อันตรายต่อโพรงฟัน จะเหนี่ยวนำให้มีการหลั่งสารที่เกี่ยวกับการอักเสบ และเกิดการละลายตัวของเนื้อฟันจากภายในโพรงฟัน (internal resorption) คณะผู้วิจัยได้ตั้งสมมติฐานว่าอินเตอร์ลิวคิน-6 (IL-6) ที่เพิ่มขึ้นในภาวะที่มีการอักเสบของโพรงฟัน มีผลต่อเซลล์โพรงฟัน โดยรบกวนสมดุลของ รีเซบเตอร์ แอคติเวเตอร์ ออฟ นิวเคลีย แฟคเตอร์ แคปปาบี ไลแกนส์ (RANKL) และออสติโอโปรติเจริน (OPG) ซึ่งมีผลกระตุ้นการเกิดเซลล์สลายกระดูก และย่อยสลายเนื้อฟัน การศึกษาด้วยอาร์ที พีซีอาร์ และเวสเทอร์นอนาไลซิส พบว่าอินเตอร์ลิวคิน-6 (1 และ 10 นาโนกรัม/มิลลิลิตร) กระตุ้นการสร้าง RANKL ทั้งในระดับอาร์เอ็นเอและโปรตีน แต่ไม่มีผลต่อ OPG และมาโ
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ศุภปีติพร, กัญญา, วรมันต์ ไวดาบ та วรศักดิ์ โชติเลอศักดิ์. การศึกษาความสัมพันธ์ของระดับการแสดงออกของยีน ที่เกี่ยวข้องกับระบบภูมิคุ้มกันกับความรุนแรงของโรคติดเชื้อไวรัสเด็งกิว : รายงานผลการวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 2009. https://doi.org/10.58837/chula.res.2009.16.

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ศึกษาความสัมพันธ์ของระดับการแสดงออกของยีน (mRNA) ที่เกี่ยวข้องกับระบบภูมิคุ้มกันกับความรุนแรงของโรคติดเชื้อไวรัสเด็งกิว ผู้เข้าร่วมการวิจัยประกอบด้วยผู้ป่วยที่ได้รับการวินิจฉัยว่าติดเชื้อไวรัสเด็งกิวและได้รับการจำแนกตามรุนแรงของการติดเชื้อ โดยใช้หลักเกณฑ์ขององค์การอนามัยโลก ตัวอย่างเลือดที่นำมาสกัด mRNA และนำมาวิเคราะห์ได้จากผู้ป่วยเด็กที่ติดเชื้อไวรัสเด็งกิวในวันที่ไข้ลง ระดับการแสดงออกของยีน IL-8, IL-1beta และ MMP-9 ในเม็ดเลือดขาวของผู้ป่วยเด็กที่เป็นโรคไข้เด็งกิว (Dengue fever) จำนวน 30 ราย ผู้ป่วยเด็กที่เป็นโรคไข้เลือดออก (Dengue hemorrhagic fever) จำนวน 19 ราย และผู้ป่วยเด็กที่มีไข้จากการ
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Chen, Yuhang, Jie Wang, Liqun Wu, Hong Chen, and Ziwei Zhang. Efficacy and safety of Chinese herbal medicines in the treatment of allergic rhinitis in children: a systematic review and meta-analysis based on randomized controlled trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.4.0076.

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Review question / Objective: Population: Children (< 18 years) who were definitively diagnosed with allergic rhinitis were included, without concomitant other diseases. No limitation on location or gender. This study will only consider randomized controlled trials (RCTs) of Chinese herbal medicine for treating patients with allergic rhinitis. Other studies, such as animal studies, reviews, case reports, non-controlled studies, and quasi-RCTs, were not included. Comparison: The control intervention is based on allergic rhinitis treatment guidelines or placebo. Outcome: Primary outcomes: Nasal i
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