Log in

Relevant bibliographies by topics / IL-6 / Dissertations / Theses

To see the other types of publications on this topic, follow the link: IL-6.

Dissertations / Theses on the topic 'IL-6'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 dissertations / theses for your research on the topic 'IL-6.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Terrades, Garcia Nekane. "Interleukin-6 (IL-6)/IL-6 receptor and persistence of inflammation in Giant Cell Arteritis. Effects of IL-6 receptor blockade with tocilizumab." Doctoral thesis, Universitat de Barcelona, 2018. http://hdl.handle.net/10803/668038.

Full text

Abstract:

Giant cell arteritis (GCA) is a chronic granulomatous vasculitis affecting large- and medium-sized vessels. This disease can lead to different symptoms related to vascular or systemic inflammation, such as fever and visual loss, and its exact etiology remains to be elucidated. Current treatment of GCA patients is based on glucocorticoids administration. However, not all patients respond properly to this treatment and the disadvantages associated to glucocorticoids promotes the search for new therapeutic alternatives. Blockade of IL-6 signaling with tocilizumab (TCZ), a humanized monoclonal an

APA, Harvard, Vancouver, ISO, and other styles

2

Fischer, Patrick. "Bedeutung der IL-6-Signaltransduktionsinhibitoren SHP2 und SOCS3 für die Desensitisierung des IL-6-Signalweges." [S.l.] : [s.n.], 2006. http://deposit.ddb.de/cgi-bin/dokserv?idn=980407699.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Dawson, Charlotte Helen. "STAT 6 and IL-4 signalling." Thesis, University of Sheffield, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.245716.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Saramago, Eduardo Alves. "O hidrogênio molecular potencializa a hipotermia e previne a hipotensão e a febre durante a inflamação sistêmica induzida por LPS." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/17/17134/tde-07022019-140036/.

Full text

Abstract:

O hidrogênio molecular (H2) exerce efeito antioxidante, anti-apoptótico e antiinflamatório. Nesse estudo testamos a hipótese que o H2 modula as mudanças cardiovasculares, inflamatórias e termorregulatórias na inflamação sistêmica (IS) induzida por lipopolissacarídeo (LPS) em diferentes doses (0,1 ou 1,5 mg/kg, intravenoso, induzindo IS moderada ou severa) em ratos machos Wistar (250-300 g). LPS ou salina foi injetada imediatamente antes do início dos 360 minutos de inalação do H2 (2% H2, 21% O2, balanceado com nitrogênio) ou ar ambiente (21% O2, balanceado com nitrogênio). A temperatura corpor

APA, Harvard, Vancouver, ISO, and other styles

5

Denz, Ulrich. "Einfluss des IL-6-sIL-6R-Fusionsproteins Hyper-IL-6 auf die Leber nach hydrodynamischer Transfektion in vivo." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=973066008.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Poe, Shaunta D. "Autocrine Effects of Catecholamines on Macrophage Release of Interleukin-6 (IL-6)." VCU Scholars Compass, 2006. http://hdl.handle.net/10156/1786.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

FURINI, Federica. "P2X7 receptor (P2X7R) in Systemic Lupus Erythematosus (SLE). Exploring a novel pathogenetic pathway." Doctoral thesis, Università degli studi di Ferrara, 2019. http://hdl.handle.net/11392/2487988.

Full text

Abstract:

Introduzione. P2X7R è un recettore extracellulare ATP-dipendente coinvolto in processi infiammatori e autoimmuni che agiscono principalmente attraverso l'attivazione dell'inflammasoma NLRP3 e il rilascio di IL-1β, ed anche tramite processi implicati nella regolazione della proliferazione dei linfociti e nell'apoptosi cellulare. Diverse osservazioni da modelli animali e studi su paziente evidenziano un possibile collegamento tra l'asse P2X7R-NLRP3 e la patogenesi del Lupus Eritematoso Sistemico (SLE). L'asse inflammasoma-P2X7R oltre alla produzione diretta di IL-1b e IL-18, è coinvolto indirett

APA, Harvard, Vancouver, ISO, and other styles

8

Correia, JosÃ Walter. "Polimorfismo -174g>C do gene de Interleucina-6 da Tuberculose Pulmonar." Universidade Federal do CearÃ, 2009. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=3567.

Full text

Abstract:

nÃo hÃ<br>O objetivo do estudo foi investigar o perfil de produÃÃo de IL-6 em pacientes com tuberculose pulmonar ativa e avaliar o papel funcional do polimorfismo -174G>C do gene de IL-6 na produÃÃo sistÃmica desta citocina. Um total de 63 pacientes e 99 controles foi estudado, sendo 38 pacientes [25(65,8%) masculinos] e 63 controles [51 (81%) masculinos] para a dosagem de IL-6, enquanto, 42 pacientes [25 (60%) masculinos] e 79 controles [62(78,5%) masculinos] para o estudo do polimorfismo. Os pacientes foram selecionados dos centros de referÃncia da rede estadual de saÃde: Dona LibÃnia, Hospi

APA, Harvard, Vancouver, ISO, and other styles

9

Pereira, Leonardo Costa. "A influência do treinamento excêntrico nos níveis séricos de IL-6 e no polimorfismo -174C/G da IL-6." reponame:Repositório Institucional da UnB, 2013. http://repositorio.unb.br/handle/10482/14374.

Full text

Abstract:

Dissertação (mestrado)—Universidade de Brasília, Programa de Pós Graduação em Ciências da Saúde, 2013.<br>Submitted by Albânia Cézar de Melo (albania@bce.unb.br) on 2013-10-18T14:52:24Z No. of bitstreams: 1 2013_LeonardoCostaPereira.pdf: 2444559 bytes, checksum: 48bcb389fa8bc06f54c9921d742aa8fe (MD5)<br>Approved for entry into archive by Guimaraes Jacqueline(jacqueline.guimaraes@bce.unb.br) on 2013-10-21T11:03:05Z (GMT) No. of bitstreams: 1 2013_LeonardoCostaPereira.pdf: 2444559 bytes, checksum: 48bcb389fa8bc06f54c9921d742aa8fe (MD5)<br>Made available in DSpace on 2013-10-21T11:03:05Z (GMT). N

APA, Harvard, Vancouver, ISO, and other styles

10

Malchow, Sven [Verfasser]. "Impact of IL-6 classic- and IL-6 trans-signaling on Concanavalin A immune-mediated liver damage / Sven Malchow." Kiel : Universitätsbibliothek Kiel, 2010. http://d-nb.info/102000407X/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

OLIVEIRA, Jacqueline Flores de. "Níveis séricos de interleucinas IL-6 e IL-10 em indivíduos com transtorno de estresse pós-traumático em uma amostra de base populacional." Universidade Catolica de Pelotas, 2018. http://tede.ucpel.edu.br:8080/jspui/handle/jspui/691.

Full text

Abstract:

Submitted by Cristiane Chim (cristiane.chim@ucpel.edu.br) on 2018-05-03T12:31:50Z No. of bitstreams: 1 JACQUELINE FLORES DE OLIVEIRA 2018.pdf: 1047235 bytes, checksum: aa5d647bf60bee68ec295537b66e13f6 (MD5)<br>Made available in DSpace on 2018-05-03T12:31:50Z (GMT). No. of bitstreams: 1 JACQUELINE FLORES DE OLIVEIRA 2018.pdf: 1047235 bytes, checksum: aa5d647bf60bee68ec295537b66e13f6 (MD5) Previous issue date: 2018-01-04<br>Conselho Nacional de Pesquisa e Desenvolvimento Científico e Tecnológico - CNPq#<br>#-2555911436985713659#<br>#600<br>Post-traumatic stress disorder (PTSD) is a psychiatric

APA, Harvard, Vancouver, ISO, and other styles

12

Мозгова, Юлія Анатоліївна, Юлия Анатольевна Мозговая та Yuliia Anatoliivna Mozghova. "Динаміка вмісту IL-4 та IL-6 при хронічному тонзиліті в дітей". Thesis, Сумський державний університет, 2013. http://essuir.sumdu.edu.ua/handle/123456789/32359.

Full text

Abstract:

Хронічне запалення піднебінних мигдаликів є розповсюдженим захворюванням дитячого віку, що несприятливо впливає на зростаючий організм. На хронічний тонзиліт страждає більше 2-3% дітей раннього віку, 6-7% - дошкільного та 8-9% школярів. При цитуванні документа, використовуйте посилання http://essuir.sumdu.edu.ua/handle/123456789/32359

APA, Harvard, Vancouver, ISO, and other styles

13

Cirocco, Robert E. "Cytokine analisys in atlantic bottlenose dolphins: molecular characterization of IL-4, IL-6, and IL-10." FIU Digital Commons, 2001. http://digitalcommons.fiu.edu/etd/2370.

Full text

Abstract:

The health status of wild and captive Atlantic Bottlenose dolphins (Tersiops truncatis) is difficult to ascertain. Mass strandings of these animals have been attributed to pollutants, as well as bacterial infections. Using human Enzyme Linked Immuno-Assays (ELISA) for immunological cytokines, I measured soluble cytokine levels with respect to their health status. In a retrospective analysis of dolphin sera, there was a trend of higher cytokine levels in “sick” animals. I cultured dolphin lymphocytes in the presence of a mitogen (PHA), a super antigen (Staph-A), Lipopolysaccharide (LPS), and a

APA, Harvard, Vancouver, ISO, and other styles

14

Woolley, Jane Alison. "The production, assessment and application of antibodies to human interleukin-6 (IL-6)." Thesis, Queen Mary, University of London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338809.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Champa, Zachary J. "Modulation of IL-6 and IL-8 Expression in Ovarian Cancer Cells by a Small OrganicCompound." Ohio University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1460987166.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Erta, Cañabate Maria. "Role of astrocytic IL-6 and IL-6R in normal physiology and neuroinflammation." Doctoral thesis, Universitat Autònoma de Barcelona, 2014. http://hdl.handle.net/10803/275952.

Full text

Abstract:

La Interleucina 6 (IL-6) és una citocina altament multifuncional, amb moltes accions pleiotròpiques, considerada una de les principals citocines controlant el sistema immune i coordinant-lo amb els sistemes nerviós i endocrí. La IL-6 es produeix en molts tipus cel·lulars dins del sistema nerviós central (SNC) i al seu torn, múltiples cèl·lules hi poden respondre. Per tant, és necessari caracteritzar quina és la contribució específica de cada tipus cel·lular en el paper global de la IL-6, tant en condicions fisiològiques com patològiques. Com que els astròcits tenen una important resposta enfro

APA, Harvard, Vancouver, ISO, and other styles

17

Dewolf-Pieuchot, Nicole. "L'Enfant de 6 ans et la lecture comment il pense, comment il apprend /." Lille 3 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb37617548n.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Sasser, Amy Kate. "The role of stromal fibroblasts and IL-6 in breast cancer progression." Columbus, Ohio : Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1172866243.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Harré, Eva-Maria. "Die Rolle von Interleukin-6 (IL-6) in der zentralnervös vermittelten Fieberentstehung der Ratte." Wettenberg : VVB Laufersweiler, 2003. http://deposit.d-nb.de/cgi-bin/dokserv?idn=968960545.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Manjavachi, Marianne Neves. "Mecanismos envolvidos na hipernocicepção mecânica muscular induzida pela Interleucina-6 (IL-6) em camundongos." reponame:Repositório Institucional da UFSC, 2012. http://repositorio.ufsc.br/xmlui/handle/123456789/93523.

Full text

Abstract:

Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2010<br>Made available in DSpace on 2012-10-24T23:37:57Z (GMT). No. of bitstreams: 1 278034.pdf: 787631 bytes, checksum: 4e1a362ea442a16afcf597e48553d44d (MD5)<br>O objetivo do presente estudo foi investigar os possíveis mecanismos e mediadores envolvidos na hipernocicepção mecânica muscular induzida pela administração intramuscular (i.m.) de IL-6, no músculo gastrocnêmio de camundongos. Foi demonstrado que a injeção i.m. de IL-6 (3, 6 ou 10

APA, Harvard, Vancouver, ISO, and other styles

21

Lopes, Fernando Henrique Azevedo. "NÃveis sÃricos de interleucina-6 e polimorfismo - 174G>C em infecÃÃo latente pelo Mycobacterium tuberculosis." Universidade Federal do CearÃ, 2012. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=7533.

Full text

Abstract:

CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>A interleucina-6 (IL-6) Ã uma importante citocina que exerce papel fundamental na imunopatogÃnese de diversas doenÃas infecciosas. O objetivo deste estudo foi investigar o nÃvel de produÃÃo sistÃmica de IL-6 e aferir o papel funcional do polimorfismo -174 G>C do gene dessa citocina em indivÃduos diagnosticados como portadores de infecÃÃo latente pelo Mycobacterium tuberculosis (ILTB). Para controle, foram utilizados dois grupos de comparaÃÃo: um deles composto por portadores de tuberculose pulmonar ativa (TB) e o outro formado por

APA, Harvard, Vancouver, ISO, and other styles

22

Berg, Arjen van den. "Post-transcriptional modulation of IL-6 and IL-8 responses in structural airway cells." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2006. http://dare.uva.nl/document/32479.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

ARAÚJO, Maria da Conceição Melo. "Polimorfismo nos genes il-1 e il-6 e o insucesso de implantes dentários." UNIVERSIDADE FEDERAL DE PERNAMBUCO, 2014. https://repositorio.ufpe.br/handle/123456789/14987.

Full text

Abstract:

Submitted by Isaac Francisco de Souza Dias (isaac.souzadias@ufpe.br) on 2016-01-25T16:57:05Z No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Dissertação - Formato Digital2.pdf: 1376666 bytes, checksum: 9522835840997f24e4c9a259f0bf5fab (MD5)<br>Made available in DSpace on 2016-01-25T16:57:05Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) Dissertação - Formato Digital2.pdf: 1376666 bytes, checksum: 9522835840997f24e4c9a259f0bf5fab (MD5) Previous issue date: 2014-08-26<br>REUNI<br>Objetiva

APA, Harvard, Vancouver, ISO, and other styles

24

Klebow, Sabrina [Verfasser]. "The role of theproinflammatory cytokines IL-17, IL-6 and IL-1 in (IMQ-induced) psoriasis / Sabrina Klebow." Mainz : Universitätsbibliothek Mainz, 2016. http://d-nb.info/1111809518/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Palmer, Jodie. "The IL-6 type cytokine family in prostate cancer." Monash University, Centre for Functional Genomics and Human Disease, 2003. http://arrow.monash.edu.au/hdl/1959.1/9441.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Ayala-Fontanez, Nilmarie. "Paradoxical onset of psoriasis after IL-6 receptor blockade." Case Western Reserve University School of Graduate Studies / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=case1436396399.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Schebesta, Kathrin [Verfasser]. "Das Endothel sezerniert Interleukin-6 (IL-6) und stimuliert die adrenale Interleukin-6 und Aldosteronsynthese über einen Interleukin-6 unabhängigen Mechanismus / Kathrin Schebesta." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2015. http://d-nb.info/1079652612/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Peron, Jean Pierre Schatzmann. "O fenômeno da tolerância oral e a regulação de células patogênicas Th17 no modelo de encefalomielite experimental auto-imune." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/42/42133/tde-17092008-113606/.

Full text

Abstract:

Recentemente demonstrou-se o papel de células T produtoras de IL-17 na patogênese da esclerosa múltipla e de seu modelo, a EAE. Através da produção desta e de outras citocinas, a população chamada Th17 promove o rompimento da barreira hematoencefálica e a conseqüente infiltração de células patogênicas para dentro do SNC. Nesse contexto, em nosso trabalho utilizamos o fenômeno da tolerância oral para avaliar a capacidade deste em suprimir a resposta imune durante o modelo de EAE, mais especificamente as células Th17. Nossos dados demonstram uma diminuição de IL-17 tanto na periferia como no SN

APA, Harvard, Vancouver, ISO, and other styles

29

Loung, Le Anh. "Genetic variations in the interleukin-6(IL-6) gene : implication in coronary heart disease (CHD)." Thesis, University College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406589.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Vilela, Josie Fadul 1982. "Investigação dos polimorfismos dos genes da interleucina-1 (IL-1), IL1RN, IL-4, IL-6 e IL-10 em pacientes adultos portadores de púrpura trombocitopênica imune = Investigation of interleukin-1 (IL-1), IL1RN, IL-4, IL-6 and IL-10 gene polymorphism adult patients with immune thrombocytopenic purpura." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310653.

Full text

Abstract:

Orientador: Marcelo Addas Carvalho<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-21T03:08:54Z (GMT). No. of bitstreams: 1 Vilela_JosieFadul_M.pdf: 1739915 bytes, checksum: ea1d6c47907a49ccd0e00255b01d3dee (MD5) Previous issue date: 2012<br>Resumo: A Púrpura Trombocitopênica Imune (PTI) é uma doença autoimune caracterizada pela presença de autoanticorpos contra as glicoproteínas de membrana plaquetária, tais como GPIIb/IIIa e GPIb/IX. O processo patogênico da PTI envolve uma destruição acelerada das plaqueta

APA, Harvard, Vancouver, ISO, and other styles

31

Gil, Ibánez Inés [Verfasser], and Henning [Akademischer Betreuer] Wege. "Ligand-independent IL-6 pathway activation (L-gp130) accelerates the transformation of proliferating human hepatocytes via increased oxidative stress in comparison to ligand-dependent IL-6 pathway activation (Hyper-IL-6) / Inés Gil Ibánez. Betreuer: Henning Wege." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2015. http://d-nb.info/1079655220/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Shive, Carey Lynn. "The impact of inflammatory cytokines, il-6 and il-1beta, on the pathogenesis of immune failure in HIV disease." Case Western Reserve University School of Graduate Studies / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=case1396627515.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

DESIATO, GENNI. "Regulation of the GABA switch by immunomodulatory signals." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2018. http://hdl.handle.net/10281/199045.

Full text

Abstract:

L'acido Gamma Amino butirrico, noto come GABA, rappresenta il principale neurotrasmettitore inibitorio del Sistema Nervoso nell'individuo adulto. Tuttavia, durante le precoci fasi di sviluppo, il GABA ha attività depolarizzante ed eccitatoria, fondamentale per il successivo e corretto sviluppo della rete. Il "GABA switch" rappresenta quindi un evento critico dello sviluppo neuronale, caratterizzato da uno shift funzionale della trasmissione GABAergica, da eccitatoria a inibitoria, le cui alterazioni sono comuni caratteristiche dei disordini del neurosviluppo, solitamente associati a disabilità

APA, Harvard, Vancouver, ISO, and other styles

34

Pereira, Daniele Sirineu. "Efeito do polimorfismo -174 G/C da região promotora do gene IL-6, índices plasmáticos de IL-6 e força muscular de mulheres idosas." Universidade Federal de Minas Gerais, 2008. http://hdl.handle.net/1843/MSMR-7WYHM5.

Full text

Abstract:

The present study investigates the effect of -174 G/C promoter polymorphism of the interleukin-6 (IL-6) gene on the plasmatic levels of IL-6 and muscular strength, as well as the association between doses of IL-6 and the muscular strength of elderly women. The sample consisted of 199 institutionalized and community-living elderly patients (73.0 ± 7.8 years) in the city of Belo Horizonte, Brazil. The -174 G/C polymorphism in the promoter of the human IL-6 gene was determined by direct sequencing of a polymerase chain reaction product. The plasmatic concentrations of IL-6 were measured using the

APA, Harvard, Vancouver, ISO, and other styles

35

Ferrer, Villahoz Beatriz. "Influencia de la citoquina Interleuquina 6 (IL-6) adipocitaria y muscular en el control del metabolismo." Doctoral thesis, Universitat Autònoma de Barcelona, 2013. http://hdl.handle.net/10803/116320.

Full text

Abstract:

La interleuquina -6 (IL-6) es una citoquina pleiotrópica cuya función principal se da en el sistema inmune en el control de la inflamación. Realiza importantes funciones en la homeostasis del sistema nervioso central (SNC), en la respuesta al ejercicio físico e incluso en el metabolismo (particularmente en funciones relacionadas con la insulina). Diversos estudios han demostrado que la IL-6 podría tener un papel en el control del peso corporal tanto a nivel de SNC como periférico, aunque no está claro si la IL-6 endógena que participa en la regulación del peso corporal a nivel del SNC procede

APA, Harvard, Vancouver, ISO, and other styles

36

Yan, Jin, Ohannes Melemedjian, Theodore Price, and Gregory Dussor. "Sensitization of dural afferents underlies migraine-related behavior following meningeal application of interleukin-6 (IL-6)." BioMed Central, 2012. http://hdl.handle.net/10150/610216.

Full text

Abstract:

BACKGROUND:Migraine headache is one of the most common neurological disorders, but the pathophysiology contributing to migraine is poorly understood. Intracranial interleukin-6 (IL-6) levels have been shown to be elevated during migraine attacks, suggesting that this cytokine may facilitate pain signaling from the meninges and contribute to the development of headache.METHODS:Cutaneous allodynia was measured in rats following stimulation of the dura with IL-6 alone or in combination with the MEK inhibitor, U0126. The number of action potentials and latency to the first action potential peak in

APA, Harvard, Vancouver, ISO, and other styles

37

Shakya, Astha. "ERK3 negatively regulates the IL-6/STAT3 signaling via SOCS3." Wright State University / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=wright1576834819053154.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Lin, Wai Wai. "TRAF3 regulates B cell survival and IL-6 receptor signaling." Diss., University of Iowa, 2015. https://ir.uiowa.edu/etd/1678.

Full text

Abstract:

Tumor-necrosis factor (TNF)-receptor (R) associated factor 3 (TRAF3) is an important adaptor protein that plays a variety of context-dependent regulatory roles in all types of immune cells. In B cells, TRAF3 mediates signaling downstream of CD40, B cell activating factor (BAFF)-R, and toll-like receptors (TLR)s to restrain B cell survival and function. Downstream of CD40 and BAFF-R, TRAF3 negatively regulates NF-κB2 activation through NF-κB inducing kinase (NIK) stabilization. NF-κB2 activation is important for B cell-homeostatic survival. However, the constitutively active NF-κB2 in other TRA

APA, Harvard, Vancouver, ISO, and other styles

39

Kurth, Ingo. "Untersuchungen zur Zytokinbindung und Rezeptoraktivierung des Signaltransduktors gp130 durch seine Liganden IL-6 und IL-11." [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=968740758.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Gallion-Rochette, Emmanuelle. "Adaptations cellulaires et moléculaires de la réponse inflammatoire à l'activité physique chez les enfants atteints d'arthrite juvénile idiopathique." Thesis, Université Clermont Auvergne‎ (2017-2020), 2018. http://www.theses.fr/2018CLFAC030.

Full text

Abstract:

L'arthrite juvénile idiopathique (AJI) est une maladie rare chronique caractérisée par une inflammation persistante qui se manifeste par des douleurs articulaires, le gonflement des articulations et la limitation des mouvements articulaires. La fatigue et les douleurs entraînent une diminution de l'activité physique et une sédentarité accrue. Ce manque d'activité physique a pour conséquence une altération de la qualité de vie et une aggravation de la fatigue chronique, des troubles de l'humeur et des troubles métaboliques chez ces enfants. Les études sur les programmes d'exercices physiques mo

APA, Harvard, Vancouver, ISO, and other styles

41

Guillot, Xavier. "Effets thérapeutiques et anti-inflammatoires de la cryothérapie dans les rhumatismes inflammatoires." Thesis, Besançon, 2016. http://www.theses.fr/2016BESA3009/document.

Full text

Abstract:

La cryothérapie est utilisée de manière large et empirique à visée adjuvante dans les rhumatismes inflammatoires, avec un niveau de preuve faible. Dans une revue systématique de la littérature, en poolant les données de 6 études non contrôlées, nous avons pu démontrer que la cryothérapie (locale ou corps entier) appliquée deux fois par jour pendant 7 à 15 jours réduisait significativement l'EVA douleur et le score d'activité DAS25 dans la polyarthrite rhumatoïde. La cryothérapie locale (glace ou gaz froide) montrait par ailleurs des effets taille intra-classes supérieurs à ceux obtenus en util

APA, Harvard, Vancouver, ISO, and other styles

42

DiLorenzo, Frank Michael. "The Effects of Dha Supplementation on Markers of Inflammation and Muscle Damage Following an Acute Eccentric Exercise Bout." Thesis, Virginia Tech, 2012. http://hdl.handle.net/10919/43760.

Full text

Abstract:

Aim: The purpose of this study was to investigate the influence of docosahexaenoic acid (DHA) on muscle damage and inflammation following an acute eccentric exercise bout. Methods: A double-blind placebo-controlled, study was performed using 41 healthy, untrained males aged 18-28 y who consumed either 2 g/d DHA or placebo (PL, corn oil) for 32 days. Supplements were consumed for 28 days prior to exercise. Participants completed an eccentric exercise procedure of the elbow flexors at 140% of 1-RM (6 sets x 10 repetitions). The time under tension (TUT) for each set of eccentric contractions was

APA, Harvard, Vancouver, ISO, and other styles

43

Broch, i. Montané Montserrat. "Contribució de les citocines proinflamatòries, factor de necrosi tumoral alfa (tnea) i interleucina 6 (il-6), a la resistència a la insulina. Estudi serològic i genètic." Doctoral thesis, Universitat Rovira i Virgili, 2002. http://hdl.handle.net/10803/8748.

Full text

Abstract:

La Diabetes mellitus tipo 2 (DM2) está causada principalmente por la disminución de la acción de la insulina (resistencia a la insulina) y por el deterioramiento de la función de las células beta. La DM2 y la obesidad se hallan íntimamente relacionadas. Así, el tejido adiposo es capaz de sintetizar y secretar diversas moléculas que se han visto implicadas en la modulación de la sensibilidad a la insulina (Si). Entre estas moléculas están las citocinas Factor de Necrosis Tumoral alfa (TNF) y la Interleucina 6 (IL-6).<br/>El TNF actúa mediante los receptores TNFR1 y TNFR2. La uni

APA, Harvard, Vancouver, ISO, and other styles

44

Harré, Eva-Maria [Verfasser]. "Die Rolle von Interleukin-6 (IL-6) in der zentralnervös vermittelten Fieberentstehung der Ratte / Eva-Maria Harré." Wettenberg : VVB Laufersweiler, 2003. http://d-nb.info/968960545/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Silva, Ítala Cristine. "Papel da interleucina 6 (IL-6) na resposta inflamatória neutrofílica durante a infecção por Leishmania infantum>." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/17/17147/tde-06062017-170957/.

Full text

Abstract:

As leishmanioses são um conjunto de doenças causadas pela infecção com protozoários do gênero Leishmania. No Brasil, o parasita L. infantum provoca a manifestação de uma doença sistêmica e crônica, conhecida como leishmaniose visceral (VL), que, quando não tratada, pode levar o indivíduo à óbito. A gravidade da leishmaniose visceral vem sendo associada ao aumento do nível sistêmico de IL- 6 em pacientes sintomáticos. Ainda não está claro como o aumento dessa citocina coordena a progressão da doença. Nós demonstramos durante a infecção por L. infantum experimental há produção dessa citocina nos

APA, Harvard, Vancouver, ISO, and other styles

46

Habowski, Scott. "Effects of the IL-6 Gene Polymorphism -174G/C on Interleukin-6 Production and Endurance Exercise Performance." Kent State University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=kent1532023529854917.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Hata, Hiroshi. "Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell-mediated spontaneous autoimmune arthritis in mice". Kyoto University, 2005. http://hdl.handle.net/2433/145302.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Holmes, Anna Greer, and not supplied. "Role of interleukin-6 in states of metabolic health and disease." RMIT University. Medical Sciences, 2006. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20070131.121620.

Full text

Abstract:

Obesity and type 2 diabetes are the most prevalent metabolic diseases affecting over 50% of people in the western world. Although the pathogenesis of type 2 diabetes is not fully understood, growing evidence links this disease to a state of chronic inflammation, which occurs in metabolically active tissue such as the liver, adipose tissue and skeletal muscle and results in the secretion of inflammatory cytokines, of which interleukin-6 (IL-6) is one. It is generally accepted that elevations in the plasma and/or tissue of this family of cytokines have a negative effect on whole body

APA, Harvard, Vancouver, ISO, and other styles

49

Nguyen, Loan. "The role of interleukin-1 receptors in brain cell signalling." Thesis, University of Manchester, 2010. https://www.research.manchester.ac.uk/portal/en/theses/the-role-of-interleukin1-receptors-in-brain-cell-signalling(78c927ce-a654-4eac-b2d7-2ca4ca8c0fd4).html.

Full text

Abstract:

IL-1α and IL-1β are two IL-1 agonists which signals at the same receptor complex composed of IL-1R1/IL-1RAcP. However, IL-1α and IL-1β exert differential actions. A recent CNS-specific IL-1 receptor accessory protein, called IL-1RAcPb, has been characterised but its actions are unknown. In T cell line, over expression of IL-1RAcPb negatively regulate IL-1 action (Smith et al, 2009), but over-expression of IL-1RAcPb in HEK cell line induces IL-1 signaling (Lu et al, 2008). The role of IL-1RAcPb has not been studied in primary cells. The aim of this project was to investigate the role of IL-1RAc

APA, Harvard, Vancouver, ISO, and other styles

50

Gagnon, Julien. "Les effets synergiques des cytokines pro-inflammatoires et des cytokines impliquées dans l’homéostasie sur les réponses des lymphocytes T CD8 aux antigènes." Thèse, Université de Sherbrooke, 2016. http://hdl.handle.net/11143/8777.

Full text

Abstract:

Résumé : L’IL-7 et l’IL-15 sont des cytokines impliquées dans l’homéostasie des lymphocytes T CD8 naïfs et mémoires respectivement. Lors d’une réponse immunitaire, certaines cytokines pro-inflammatoires, comme l’IL-6 et l’IL-21, sont produites par les cellules du système immunitaire inné. Nous avons observé que certaines cytokines de ces deux groupes (homéostasie et pro-inflammatoires), peuvent avoir un effet synergique sur la fonction des lymphocytes T CD8. Spécifiquement, l’incubation des lymphocytes T CD8 naïfs avec l’IL-6 ou l’IL-21, en présence d’IL-7 ou d’IL-15 cause une forte proliférat

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!