Academic literature on the topic 'Ileal microbiome'

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Journal articles on the topic "Ileal microbiome"

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Olaisen, Maya, Arnar Flatberg, Atle van Beelen Granlund, et al. "Bacterial Mucosa-associated Microbiome in Inflamed and Proximal Noninflamed Ileum of Patients With Crohn’s Disease." Inflammatory Bowel Diseases 27, no. 1 (2020): 12–24. http://dx.doi.org/10.1093/ibd/izaa107.

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Abstract Background Microbiota is most likely essential in the pathogenesis of Crohn’s disease (CD). Fecal diversion after ileocecal resection (ICR) protects against CD recurrence, whereas infusion of fecal content triggers inflammation. After ICR, the majority of patients experience endoscopic recurrence in the neoterminal ileum, and the ileal microbiome is of particular interest. We have assessed the mucosa-associated microbiome in the inflamed and noninflamed ileum in patients with CD. Methods Mucosa-associated microbiome was assessed by 16S rRNA sequencing of biopsies sampled 5 and 15 cm o
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Wang, Leli, Yiru Zhang, Juan Xu, et al. "Biosynthetic Gene Clusters from Swine Gut Microbiome." Microorganisms 11, no. 2 (2023): 434. http://dx.doi.org/10.3390/microorganisms11020434.

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The abuse of antibiotics has become a serious health challenge in the veterinary field. It creates environmental selection pressure on bacteria and facilitates the rapid spread of antibiotic resistance genes. The speed of discovery and application of cost-effective alternatives to antibiotics is slow in pig production. Natural products from biosynthetic gene clusters (BGCs) represent promising therapeutic agents for animal and human health and have attracted extraordinary passion from researchers due to their ability to participate in biofilm inhibition, stress resistance, and the killing of c
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Olaisen, M., A. Flatberg, A. van Beelen Granlund, et al. "P833 Bacterial mucosa-associated microbiome in inflamed and proximal non-inflamed ileum of patients with Crohn’s disease." Journal of Crohn's and Colitis 14, Supplement_1 (2020): S645—S646. http://dx.doi.org/10.1093/ecco-jcc/jjz203.961.

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Abstract Background The microbiota most likely has an essential role in the pathogenesis of Crohn’s disease (CD). While faecal diversion after ileocecal resection (ICR) protects against CD recurrence, re-exposure triggers inflammation. After ICR, the majority of patients develop recurrence in the neoterminal ileum and the ileal microbiome is of particular interest. We have therefore assessed the mucosa-associated bacterial microbiome in the inflamed and non-inflamed ileum of patients with CD. Methods Patients with an established diagnosis of CD undergoing ileocolonoscopy and healthy controls (
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Zhen, Yongkang, Chong Zhang, Jiaqi Lin, Ali Rahmat, Feiyang He, and Mengzhi Wang. "Effects of Exogenous Oral Infusion of Volatile Fatty Acids on Ileal Microbiome Profiling and Epithelial Health in Goats." Fermentation 9, no. 9 (2023): 801. http://dx.doi.org/10.3390/fermentation9090801.

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The role of volatile fatty acids (VFAs) in ruminal fermentation is well studied, but their effects on the ileal microbiome and epithelial health remain less explored. In this study, we investigated the impact of the exogenous oral infusion of three VFAs, sodium acetate (NaAc), propionate (NaPr), and butyrate (NaBu), on the VFA concentrations in ileal contents, as well as ileal microbiome profiling and epithelial health parameters (inflammatory cytokine and tight junctions) in goats. The data demonstrated that the oral infusion of three VFAs can enhance VFA production by increasing the proporti
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Kneis, Barbara, Stefan Wirtz, Klaus Weber, et al. "Colon Cancer Microbiome Landscaping: Differences in Right- and Left-Sided Colon Cancer and a Tumor Microbiome-Ileal Microbiome Association." International Journal of Molecular Sciences 24, no. 4 (2023): 3265. http://dx.doi.org/10.3390/ijms24043265.

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In the current era of precision oncology, it is widely acknowledged that CRC is a heterogeneous disease entity. Tumor location (right- or left-sided colon cancer or rectal cancer) is a crucial factor in determining disease progression as well as prognosis and influences disease management. In the last decade, numerous works have reported that the microbiome is an important element of CRC carcinogenesis, progression and therapy response. Owing to the heterogeneous nature of microbiomes, the findings of these studies were inconsistent. The majority of the studies combined colon cancer (CC) and r
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Junior, Sudario Roberto Silva, Jinlong Zhu, Chi Chen, et al. "221 Modulation of gut microbiome and nutrient digestibility by Aspergillus oryzae prebiotic in pigs fed high-fiber diets: A multi-omics approach." Journal of Animal Science 103, Supplement_1 (2025): 48–49. https://doi.org/10.1093/jas/skaf102.053.

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Abstract Traditional evaluations of feed additives in swine diets have primarily focused on performance metrics, but improving nutrient utilization from high-fiber diets requires a deeper understanding of the interactions among diet, gut microbiome, and digestibility. Therefore, a multi-omics approach is necessary to explore these complex relationships. The objective of this study was to investigate the effects of dietary inclusion of an Aspergillus oryzae prebiotic (AOP; Amaferm®, BioZyme Inc.) on the gut microbiome and metabolome of growing pigs fed high-fiber diets, and to examine associati
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Calzadilla, Nathan, Dulari Jayawardena, Aisha Qazi, et al. "Serotonin Transporter Deficiency Induces Metabolic Alterations in the Ileal Mucosa." International Journal of Molecular Sciences 25, no. 8 (2024): 4459. http://dx.doi.org/10.3390/ijms25084459.

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Serotonin transporter (SERT) deficiency has been implicated in metabolic syndrome, intestinal inflammation, and microbial dysbiosis. Interestingly, changes in microbiome metabolic capacity and several alterations in host gene expression, including lipid metabolism, were previously observed in SERT−/− mice ileal mucosa. However, the precise host or microbial metabolites altered by SERT deficiency that may contribute to the pleiotropic phenotype of SERT KO mice are not yet understood. This study investigated the hypothesis that SERT deficiency impacts lipid and microbial metabolite abundances in
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da Silva, Julia Marixara Sousa, Ana Maria De Souza Almeida, Ana Carolina Borsanelli, et al. "Intestinal Microbiome Profiles in Broiler Chickens Raised with Different Probiotic Strains." Microorganisms 12, no. 8 (2024): 1639. http://dx.doi.org/10.3390/microorganisms12081639.

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The composition of the intestinal microbiota can influence the metabolism and overall functioning of avian organisms. Therefore, the objective of this study was to evaluate the effect of three different probiotics and an antibiotic on the microbiomes of 1.400 male Cobb® broiler raised for 42 days. The experiment was conducted with the following treatments: positive control diet (basal diet + antibiotic); negative control diet (basal diet without antibiotic and without probiotic); basal diet + Normal Avian Gut Flora (NAGF); basal diet + multiple colonizing strain probiotics (MCSPs); and basal d
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Wall, Dannica C., Dana Dittoe, Ramon D. Malherios, Kenneth E. Anderson, and Nick Anthony. "Evaluating the Ileal and Cecal Microbiota Composition of a 1940 Heritage Genetic Line and a 2016 Commercial Line of white Leghorns Fed Representative Diets from 1940 to 2016." Applied Sciences 13, no. 22 (2023): 12259. http://dx.doi.org/10.3390/app132212259.

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This study identified and evaluated differences between microbiome compositions of the ileum and ceca of 1940 and 2016 white leghorn genetic strains fed representative contemporary diets from those times. Ileal and cecal samples were collected at 69 weeks of age. Alpha and beta diversity metrics were generated, and the Analysis of Composition of Microbiomes (ANCOM) was utilized to determine significantly different taxa. Ileum and ceca alpha diversity were significantly different (p = 0.001; Q = 0.001); however, no differences between genetic lineage were observed (p > 0.05; Q > 0.05). Be
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Nana, Gael, Suparna Mitra, Henry Watson та ін. "Luminal Bioavailability of Orally Administered ω-3 PUFAs in the Distal Small Intestine, and Associated Changes to the Ileal Microbiome, in Humans with a Temporary Ileostomy". Journal of Nutrition 151, № 8 (2021): 2142–52. http://dx.doi.org/10.1093/jn/nxab113.

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ABSTRACT Background Oral administration of purified omega-3 (ω-3) PUFAs is associated with changes to the fecal microbiome. However, it is not known whether this effect is associated with increased PUFA concentrations in the gut. Objectives We investigated the luminal bioavailability of oral ω-3 PUFAs (daily dose 1 g EPA and 1g DHA free fatty acid equivalents as triglycerides in soft-gel capsules, twice daily) and changes to the gut microbiome, in the ileum. Methods Ileostomy fluid (IF) and blood were obtained at baseline, after first capsule dosing (median 2 h), and at a similar time after fi
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Dissertations / Theses on the topic "Ileal microbiome"

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Glavan, Tiffany Wallingford. "Molecular Analysis Reveals Unique Microbiome in Ileal Pouch During Pouchitis Compared to Healthy Pouches in Ulcerative Colitis and Familial Adenomatous Polyposis." DigitalCommons@CalPoly, 2011. https://digitalcommons.calpoly.edu/theses/543.

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In severe cases of ulcerative colitis (UC) unresponsive to current treatment options, patients require a complete proctocolectomy, or surgical removal of the colon. Ileal pouch anal anastomosis (IPAA) has become the preferred surgical technique for patients who require surgery, as this method restores rectal function. This procedure is also used to treat colorectal cancers such as adenocarcinoma and familial adenomatous polyposis (FAP). The surgery involves an abdominal colectomy with the construction of an ileal pouch created from folded tissue recovered from the ileal portion of the small in
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Ta, Allison D. M. D. "Baseline Luminal Narrowing is Associated with Ileal Microbial Shifts and Gene Expression Programs and Subsequent Transmural Healing in Pediatric Crohn’s Disease." University of Cincinnati / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1617105155605576.

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Patrascu, Isabelle. "Description des systèmes enzymatiques du microbiote iléal humain associés à la dégradation des fibres alimentaires et exploration du microbiote fécal d'un individu obèse : approche de métagénomique fonctionnelle et recherche de glycoside hydrolases inédites." Thesis, Université Paris-Saclay (ComUE), 2017. http://www.theses.fr/2017SACLS098.

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La fermentation des fibres alimentaires est l’une des fonctions majeures du microbiote intestinal humain. Les bactéries fibrolytiques synthétisent un grand nombre d’enzymes, appelées Glycoside Hydrolases (GH), indispensables à la déconstruction de la grande variété structurelle des polysaccharides pariétaux que nous ingérons. Au cours de ce travail, nous avons exploré, grâce à une approche de métagénomique fonctionnelle, l’organisation et les propriétés des systèmes enzymatiques bactériens impliqués dans la dégradation des glycanes de parois végétales dans l’intestin humain.En premier lieu, no
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Torres, Karoll Andrea Alfonso [UNESP]. "Avaliação do desempenho zootécnico, da função da mucosa intestinal e da microbiota ileal quando da substituição do milho pelo sorgo na ração de frangos de corte." Universidade Estadual Paulista (UNESP), 2010. http://hdl.handle.net/11449/104936.

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Made available in DSpace on 2014-06-11T19:33:32Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-02-24Bitstream added on 2014-06-13T19:04:37Z : No. of bitstreams: 1 torres_kaa_dr_jabo.pdf: 619941 bytes, checksum: e0160fe883801063a539b7087e557875 (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>Experimento 1: Foram avaliados os efeitos da substituição do milho pelo sorgo na ração para frangos de corte sobre o desempenho, o rendimento de carcaça e partes, a morfometria (densidade de vilos, altura dos vilos, profundidade das criptas, número de células calici
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Almeida, Maristela Gomes de. ""Estudo da microbiota intestinal em doentes com retocolite ulcerativa antes e após retocolectomia com anastomose de bolsa ileal ao canal anal"." Universidade de São Paulo, 2004. http://www.teses.usp.br/teses/disponiveis/5/5154/tde-19102005-160653/.

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Este estudo tem como objetivo, descrever a microbiota intestinal de pacientes com retocolite ulcerativa grave, em tratamento clínico, antes e após retocolectomia com anastomose de bolsa ileal ao canal anal. Comparou-se a flora bacteriana do íleo terminal e do reto no pré-operatório com a flora encontrada na bolsa ileal após dois e oito meses do fechamento da ileostomia e com a flora do íleo terminal e do reto de um grupo controle. Observou-se que a Veillonella sp foi a bactéria mais freqüentemente encontrada em todos os grupos. Não houve diferenças significativas entre a flora intestinal do gr
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Torres, Karoll Andrea Alfonso. "Avaliação do desempenho zootécnico, da função da mucosa intestinal e da microbiota ileal quando da substituição do milho pelo sorgo na ração de frangos de corte /." Jaboticabal : [s.n.], 2010. http://hdl.handle.net/11449/104936.

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Resumo: Experimento 1: Foram avaliados os efeitos da substituição do milho pelo sorgo na ração para frangos de corte sobre o desempenho, o rendimento de carcaça e partes, a morfometria (densidade de vilos, altura dos vilos, profundidade das criptas, número de células caliciformes e índice mitótico nas criptas) e a integridade da mucosa do duodeno, jejuno e íleo, e a atividade das enzimas de membrana (aminopeptidase, fosfatase alcalina e maltase) da mucosa do jejuno. Foram utilizados 792 pintainhos de um dia machos, Cobb-500, distribuídos ao acaso em quatro tratamentos (0, 50, 75 ou 100% de sub
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Cordonnier, Charlotte. "Survie et pathogénicité des EHEC dans l'environnement digestif : Interactions avec le microbiote et l'épithélium intestinal. : Influence de l'administration de levures probiotiques." Thesis, Clermont-Ferrand 1, 2015. http://www.theses.fr/2015CLF1MM21/document.

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Les Escherichia coli entérohémorragiques (EHEC) sont des pathogènes majeurs pour l’homme responsables de toxi-infections alimentaires pouvant évoluer vers des complications potentiellement mortelles. La pathogénicité de ces souches est essentiellement due à la production de Shiga-toxines (Stx), même si d’autres facteurs semblent jouer un rôle important dans la virulence, comme des facteurs d’adhésion. La survie et la régulation des facteurs de virulence des EHEC dans l’environnement digestif humain sont des facteurs clés dans la pathogénicité bactérienne, mais restent à ce jour mal décrits, es
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Tyler, Andrea. "Understanding the Etiology of Inflammatory Complications Following Ileal Pouch-Anal Anastomosis." Thesis, 2014. http://hdl.handle.net/1807/66295.

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Introduction: Inflammatory pouch complications, including pouchitis, chronic pouchitis (CP) and a Crohn’s disease-like phenotype (CDL) of the pouch following ileal pouch-anal anastomosis (IPAA), are relatively common, and arise via unknown mechanisms. The phenotypic similarities between pouch inflammation and inflammatory bowel disease (IBD) suggest there may be common pathways involved in both disorders. The aim of this thesis is to investigate the serological, genetic and microbial factors contributing to the development of pouch inflammation in a large, well characterized patient cohort. M
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Nana, G., S. Mitra, H. Watson та ін. "Luminal Bioavailability of Orally Administered ω-3 PUFAs in the Distal Small Intestine, and Associated Changes to the Ileal Microbiome, in Humans with a Temporary Ileostomy". 2021. http://hdl.handle.net/10454/18557.

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yes<br>Background: Oral administration of purified omega-3 (ω-3) PUFAs is associated with changes to the fecal microbiome. However, it is not known whether this effect is associated with increased PUFA concentrations in the gut. Objectives: We investigated the luminal bioavailability of oral ω-3 PUFAs (daily dose 1 g EPA and 1g DHA free fatty acid equivalents as triglycerides in soft-gel capsules, twice daily) and changes to the gut microbiome, in the ileum. Methods: Ileostomy fluid (IF) and blood were obtained at baseline, after first capsule dosing (median 2 h), and at a similar time after
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""Estudo da microbiota intestinal em doentes com retocolite ulcerativa antes e após retocolectomia com anastomose de bolsa ileal ao canal anal"." Tese, Biblioteca Digital de Teses e Dissertações da USP, 2004. http://www.teses.usp.br/teses/disponiveis/5/5154/tde-19102005-160653/.

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Books on the topic "Ileal microbiome"

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I. Coskun, E. Tahtabicen, F. Koç, et al. Effects of combined in ovo injection of dried whey and Enterococcus faecium on performance, ileal histomorphology, erythrocyte morphology and ileal microbiota of broiler chickens. Verlag Eugen Ulmer, 2015. http://dx.doi.org/10.1399/eps.2015.102.

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Book chapters on the topic "Ileal microbiome"

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Naito, Yuji, Tomohisa Takagi, and Ryo Inoue. "Role of Gut Microbiota in Bile-Acid Metabolism." In Psychology and Pathophysiological Outcomes of Eating. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.100440.

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The role of the gut microbiota in modifying the pathophysiology of various diseases, including neurodegenerative diseases, is increasingly becoming clear. Bile acids have been shown to be endogenous factors that affect gut microbiota, and bile-acid metabolites directly or indirectly affect host physiology and pathophysiology. The development of metagenomic analysis for gut microbiota and systematic bile-acid measurement using LC–MS/MS has triggered a breakthrough for research in this field. Clinically, an inhibitor of the ileal bile-acid transporter (Elobixibat) was used as a therapeutic agent
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Coffey, J. Calvin, and Jarlath Bolger. "Microbiota in Pouchitis and De Novo Crohn’s Disease of the Ileal Pouch." In Pouchitis and Ileal Pouch Disorders. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-12-809402-0.00010-1.

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Conference papers on the topic "Ileal microbiome"

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Schimit, Eduarda Chiamolera. "ZOONOSES TRANSMITIDAS POR PASSERIFORMES VÍTIMAS DE TRÁFICO." In I Congresso On-line Nacional de Clínica Veterinária de Pequenos Animais. Revista Multidisciplinar em Saúde, 2021. http://dx.doi.org/10.51161/rems/2396.

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Introdução: Passeriformes são aves pequenas, conhecidos como passarinhos, reconhecidas pela presença de quatro dedos ao mesmo nível. Seu canto agradável e variação de cores atrai interesse pela criação doméstica, tornando-os importantes disseminadores de patógenos virulentos. Dentre as mais de 5.000 mil espécies destacam-se os curiós, canários e thraupidae como desejados pelos humano. Objetivo: Com este resumo objetivou-se identificar a zoonose mais frequente em aves vítimas de tráfico no Brasil e seus aspectos ambientais associados. Material e Métodos: O método adotado foi de revisão bibliogr
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