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Relevant bibliographies by topics / Imbalance of protein

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Academic literature on the topic 'Imbalance of protein'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Imbalance of protein"

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Yao, Yalin, Hao Chen, Jianxin Wang, and Yeru Wang. "Generative and Contrastive Self-Supervised Learning for Virulence Factor Identification Based on Protein–Protein Interaction Networks." Microorganisms 13, no. 7 (2025): 1635. https://doi.org/10.3390/microorganisms13071635.

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Virulence factors (VFs), produced by pathogens, facilitate pathogenic microorganisms to invade, colonize, and damage the host cells. Accurate VF identification advances pathogenic mechanism understanding and provides novel anti-virulence targets. Existing models primarily utilize protein sequence features while overlooking the systematic protein–protein interaction (PPI) information, despite pathogenesis typically resulting from coordinated protein–protein actions. Moreover, a severe imbalance exists between virulence and non-virulence proteins, which causes existing models trained on balanced

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Jensen, Kim, Stephen J. Simpson, Vivi H. Nielsen, John Hunt, David Raubenheimer, and David Mayntz. "Nutrient-specific compensatory feeding in a mammalian carnivore, the mink, Neovison vison." British Journal of Nutrition 112, no. 7 (2014): 1226–33. http://dx.doi.org/10.1017/s0007114514001664.

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Balancing of macronutrient intake has only recently been demonstrated in predators. In particular, the ability to regulate carbohydrate intake is little studied in obligate carnivores, as carbohydrate is present at very low concentrations in prey animal tissue. In the present study, we determined whether American mink (Neovison vison) would compensate for dietary nutritional imbalances by foraging for complementary macronutrients (protein, lipid and carbohydrate) when subsequently given a dietary choice. We used three food pairings, within which two macronutrients differed relative to each oth

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Derganc, Jure, Bruno Antonny, and Alenka Čopič. "Membrane bending: the power of protein imbalance." Trends in Biochemical Sciences 38, no. 11 (2013): 576–84. http://dx.doi.org/10.1016/j.tibs.2013.08.006.

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BATUWITA, RUKSHAN, and VASILE PALADE. "ADJUSTED GEOMETRIC-MEAN: A NOVEL PERFORMANCE MEASURE FOR IMBALANCED BIOINFORMATICS DATASETS LEARNING." Journal of Bioinformatics and Computational Biology 10, no. 04 (2012): 1250003. http://dx.doi.org/10.1142/s0219720012500035.

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One common and challenging problem faced by many bioinformatics applications, such as promoter recognition, splice site prediction, RNA gene prediction, drug discovery and protein classification, is the imbalance of the available datasets. In most of these applications, the positive data examples are largely outnumbered by the negative data examples, which often leads to the development of sub-optimal prediction models having high negative recognition rate (Specificity = SP) and low positive recognition rate (Sensitivity = SE). When class imbalance learning methods are applied, usually, the SE

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Mannucci, P. M., A. Tripodi, B. Bottasso, et al. "Markers of Procoagulant Imbalance in Patients with Inherited Thrombophilic Syndromes." Thrombosis and Haemostasis 67, no. 02 (1992): 200–202. http://dx.doi.org/10.1055/s-0038-1648412.

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SummaryIn 107 asymptomatic and untreated patients with inherited syndromes associated with thrombophilia (antithrombin III, protein C and protein S deficiencies), we compared in parallel two plasma peptides which reflect activation of the common coagulation pathway: the prothrombin fragment 1 + 2 (F1+2) and fibrinopeptide A (FPA). Both F1+2 and FPA were measured with simple, commercially available ELISA methods. High levels of F1+2 or FPA were found in about one fourth of the patients as a whole. When patients were divided according to the type of inherited thrombophilie syndrome, it appeared

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Squitti, Rosanna, Peter Faller, Christelle Hureau, Alberto Granzotto, Anthony R. White, and Kasper P. Kepp. "Copper Imbalance in Alzheimer’s Disease and Its Link with the Amyloid Hypothesis: Towards a Combined Clinical, Chemical, and Genetic Etiology." Journal of Alzheimer's Disease 83, no. 1 (2021): 23–41. http://dx.doi.org/10.3233/jad-201556.

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The cause of Alzheimer’s disease (AD) is incompletely defined. To date, no mono-causal treatment has so far reached its primary clinical endpoints, probably due to the complexity and diverse neuropathology contributing to the neurodegenerative process. In the present paper, we describe the plausible etiological role of copper (Cu) imbalance in the disease. Cu imbalance is strongly associated with neurodegeneration in dementia, but a complete biochemical etiology consistent with the clinical, chemical, and genetic data is required to support a causative association, rather than just correlation

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Karmazina, Irina, and Hady Al-Rihani. "Cytokines and C-Reactive Protein-Trigger of Imbalance of the Hemostasis System during Inflammation." Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 2, no. 2 (2017): 21–25. http://dx.doi.org/10.26693/jmbs02.02.021.

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Campbell, Katie M., Justin Saco, Egmidio Medina, et al. "Abstract 3818: Infrequent chromosomal loss and recurrent gains lead to imbalanced expression of HLA genes in melanoma." Cancer Research 82, no. 12_Supplement (2022): 3818. http://dx.doi.org/10.1158/1538-7445.am2022-3818.

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Abstract Introduction: Loss-of-heterozygosity (LOH) events in chromosome 6p, comprising the human leukocyte antigen (HLA) genes, have been reported in about 10% of cutaneous melanoma (compared to 20-40% of squamous cell carcinomas), while copy number gains in this region have been observed in over 50% of melanoma. Recent studies focused in HLA allelic loss have been restricted to DNA-based approaches, and have not been validated orthogonally at the RNA or protein levels. Here, using clinical melanoma biopsies and patient-derived melanoma cell lines, we show that genetic alterations in HLA gene

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Straznicka, Helena. "Protein requirement and amino acid imbalance in quail." British Poultry Science 31, no. 1 (1990): 139–45. http://dx.doi.org/10.1080/00071669008417239.

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Kimball, Scot R., and Charles H. Lang. "Mechanisms Underlying Muscle Protein Imbalance Induced by Alcohol." Annual Review of Nutrition 38, no. 1 (2018): 197–217. http://dx.doi.org/10.1146/annurev-nutr-071816-064642.

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Both acute intoxication and longer-term cumulative ingestion of alcohol negatively impact the metabolic phenotype of both skeletal and cardiac muscle, independent of overt protein calorie malnutrition, resulting in loss of skeletal muscle strength and cardiac contractility. In large part, these alcohol-induced changes are mediated by a decrease in protein synthesis that in turn is governed by impaired activity of a protein kinase, the mechanistic target of rapamycin (mTOR). Herein, we summarize recent advances in understanding mTOR signal transduction, similarities and differences between the

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Dissertations / Theses on the topic "Imbalance of protein"

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Oku, Yuki. "Local Redox Imbalance Induced by Intraorganellar Accumulation of Misfolded Proteins." Kyoto University, 2019. http://hdl.handle.net/2433/242781.

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Laugsch, Magdalena, Jochen Seebach, Hans Schnittler, and Rolf Jessberger. "Imbalance of SMC1 and SMC3 Cohesins Causes Specific and Distinct Effects." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-127228.

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SMC1 and SMC3 form a high-affinity heterodimer, which provides an open backbone of the cohesin ring, to be closed by a kleisin protein. RNAi mediated knock-down of either one heterodimer partner, SMC1 or SMC3, is expected to cause very similar if not identical phenotypes. However, we observed highly distinct, protein-specific phenotypes. Upon knock-down of human SMC1, much of SMC3 remains stable, accumulates in the cytoplasm and does not associate with other cohesin proteins. Most of the excess nuclear SMC3 is highly mobile and not or only weakly chromosome-associated. In contrast, human SMC3

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Laugsch, Magdalena, Jochen Seebach, Hans Schnittler, and Rolf Jessberger. "Imbalance of SMC1 and SMC3 Cohesins Causes Specific and Distinct Effects." Public Library of Science, 2013. https://tud.qucosa.de/id/qucosa%3A27288.

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SMC1 and SMC3 form a high-affinity heterodimer, which provides an open backbone of the cohesin ring, to be closed by a kleisin protein. RNAi mediated knock-down of either one heterodimer partner, SMC1 or SMC3, is expected to cause very similar if not identical phenotypes. However, we observed highly distinct, protein-specific phenotypes. Upon knock-down of human SMC1, much of SMC3 remains stable, accumulates in the cytoplasm and does not associate with other cohesin proteins. Most of the excess nuclear SMC3 is highly mobile and not or only weakly chromosome-associated. In contrast, human SMC3

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Parikh, Ishita. "Expression and Splicing of Alzheimer’s Disease Risk Gene Phosphatidylinositol-Binding Clathrin Assembly Protein." UKnowledge, 2014. http://uknowledge.uky.edu/physiology_etds/18.

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Recent Genome Wide Association Studies (GWAS) have identified a series of single nucleotide polymorphism (SNP)s that are associated with Alzheimer’s disease (AD). One of the SNPs, rs3851179 (G/A), is near the gene phosphatidylinositol-binding clathrin assembly protein (PICALM). To evaluate whether this SNP is associated with PICALM expression, we quantified PICALM mRNA in 56 brain cDNA samples. Using linear regression analysis, we analyzed PICALM expression relative to rs3851179, AD status, and cell type specific markers. An association was detected between rs3851179 and PICALM, microvessel mR

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DING, ZEJIN. "Diversified Ensemble Classifiers for Highly Imbalanced Data Learning and their Application in Bioinformatics." Digital Archive @ GSU, 2011. http://digitalarchive.gsu.edu/cs_diss/60.

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In this dissertation, the problem of learning from highly imbalanced data is studied. Imbalance data learning is of great importance and challenge in many real applications. Dealing with a minority class normally needs new concepts, observations and solutions in order to fully understand the underlying complicated models. We try to systematically review and solve this special learning task in this dissertation.We propose a new ensemble learning framework—Diversified Ensemble Classifiers for Imbal-anced Data Learning (DECIDL), based on the advantages of existing ensemble imbalanced learning str

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Bellini, Marilanda Ferreira [UNESP]. "Estudos imuno-histoquímico das proteínas p53, p16, Fhit, caspase 3 e antígeno Ki67 ; e citogenético molecular em lesões benignas e carcinoma de esôfago." Universidade Estadual Paulista (UNESP), 2009. http://hdl.handle.net/11449/102727.

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Made available in DSpace on 2014-06-11T19:32:14Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-02-20Bitstream added on 2014-06-13T19:42:42Z : No. of bitstreams: 1 bellini_mf_dr_sjrp.pdf: 4712849 bytes, checksum: eaed69017a355062338fd2f384e1c381 (MD5)<br>Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)<br>O carcinoma de esôfago apresenta um modelo de progressão tumoral a partir da seqüência esofagite, atrofia, displasia, carcinoma

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Bellini, Marilanda Ferreira. "Estudos imuno-histoquímico das proteínas p53, p16, Fhit, caspase 3 e antígeno Ki67 ; e citogenético molecular em lesões benignas e carcinoma de esôfago /." São José do Rio Preto : [s.n.], 2009. http://hdl.handle.net/11449/102727.

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Resumo: O carcinoma de esôfago apresenta um modelo de progressão tumoral a partir da seqüência esofagite, atrofia, displasia, carcinoma in situ e carcinoma invasivo, com algumas alterações genéticas bem estabelecidas nos estágios iniciais e avançados da carcinogênese.Contudo em lesões benignas precursoras como o megaesôfago e esofagite crônica os estudos genéticos são escassos. Portanto, com o objetivo de identificar o envolvimento de algumas proteínas que participam da regulação do ciclo celular e apoptose, no presente estudo foi avaliada a expressão das proteínas p53, p16, Fhit, caspase-3 e

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Costa, Filipa de Jesus. "The effect of amino acid imbalance in neuronal development." Master's thesis, 2019. http://hdl.handle.net/10773/28435.

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Tryptamine is a non-canonical amino acid that can be obtained in the diet, by tryptophan decarboxylation or synthesized by the gut microbiota. The tryptamine acts at the level of enteric and central nervous systems, enabling bidirectional communication between the two systems (gut-brain axis). In the central nervous system, at physiological concentrations, acts as a modulator. However, at non-physiological concentrations it has a neurotoxic effect and induces protein aggregation. This protein aggregation results from the imbalance between tryptamine and tryptophan concentrations, which leads t

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Nasim, Md Talat, A. Ghouri, B. Patel, et al. "Stoichiometric imbalance in the receptor complex contributes to dysfunctional BMPR-II mediated signalling in pulmonary arterial hypertension." 2008. http://hdl.handle.net/10454/6113.

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Heterozygous germline defects in a gene encoding a type II receptor for bone morphogenetic proteins (BMPR-II) underlie the majority of inherited cases of the vascular disorder known as pulmonary arterial hypertension (PAH). However, the precise molecular consequences of PAH causing mutations on the function of the receptor complex remain unclear. We employed novel enzymatic and fluorescence activity based techniques to assess the impact of PAH mutations on pre-mRNA splicing, nonsense-mediated decay (NMD) and receptor complex interactions. We demonstrate that nonsense and frameshift mutations t

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Σκρεπετός, Δημήτριος. "Σχεδιασμός και υλοποίηση πολυκριτηριακής υβριδικής μεθόδου ταξινόμησης βιολογικών δεδομένων με χρήση εξελικτικών αλγορίθμων και νευρωνικών δικτύων". Thesis, 2014. http://hdl.handle.net/10889/8037.

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Δύσκολα προβλήματα ταξινόμησης από τον χώρο της Βιοπληροφορικής όπως η πρόβλεψη των microRNA γονιδιών και η πρόβλεψη των πρωτεϊνικών αλληλεπιδράσεων (Protein- Protein Interactions) απαιτούν ισχυρούς ταξινομητές οι οποίοι θα πρέπει να έχουν καλή ακρίβεια ταξινόμησης, να χειρίζονται ελλιπείς τιμές, να είναι ερμηνεύσιμοι, και να μην πάσχουν από το πρόβλημα ανισορροπίας κλάσεων. Ένας ευρέως χρησιμοποιούμενος ταξινομητής είναι τα νευρωνικά δίκτυα, τα οποία ωστόσο χρειάζονται προσδιορισμό της αρχιτεκτονικής τους και των λοιπών παραμέτρων τους, ενώ και οι αλγόριθμοι εκμάθησής τους συνήθως συγκλίνουν

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Books on the topic "Imbalance of protein"

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Raymundo, Roberto B. Monetary policy, housing prices, trade imbalances and the financial crisis: Establishing links and identifying policies to protect the financial system and global coordination in the implementation of monetary policy and fiscal stimulus programs : the new role of the IMF. Yuchengco Center, De La Salle University, 2009.

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Raymundo, Roberto B. Monetary policy, housing prices, trade imbalances and the financial crisis: Establishing links and identifying policies to protect the financial system and global coordination in the implementation of monetary policy and fiscal stimulus programs : the new role of the IMF. Yuchengco Center, De La Salle University, 2009.

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Avesani, Carla Maria, Juan Jesús Carrero, Bengt Lindholm, and Peter Stenvinkel. Nutritional screening and nutritional management in dialysis patients. Edited by Jonathan Himmelfarb. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0274.

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Patients on dialysis are prone to nutritional disturbances, that is, protein-energy wasting, obesity, and imbalance in body fluids and in serum phosphorus and potassium equilibrium. Hence, specialized nutritional care is highly important and include (a) a carefully assessment of the nutritional status, (b) prescription of diet with adequate energy and nutrients to treat and prevent the development of nutritional disturbances often observed in these patients, and (c) periodic follow-up to check adherence of the prescribed diet as well as to evaluate the nutritional status and efficacy of the di

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Keshav, Satish, and Alexandra Kent. Starvation and malnutrition. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0332.

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Starvation is a state of severe malnutrition due to a reduction in macro- and micronutrient intake. The basis underlying starvation is an imbalance between energy intake and energy expenditure. The commonest cause of starvation is lack of available food, usually due to environmental, social, and economic reasons, although other causes include anorexia nervosa; depression and other psychiatric disorders; coma and disturbance of consciousness; intestinal failure; and mechanical failure of digestion, including poor dentition and intestinal obstruction. Protein energy malnutrition is usually seen

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Capone, George T. Down Syndrome. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0056.

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People with Down syndrome (trisomy 21) are distinguished by having an extra copy of chromosome 21. Chromosome 21 contains an estimated 562 genes, including 161 known to code for functional proteins, and at least 396 considered novel. Gene dosage imbalance is the primary mechanism, which results in the molecular, cellular, histological, and anatomical features characteristic of the condition. Throughout brain development, major neurobiological events go awry, resulting in a differently organized brain and characteristic developmental delays noted during infancy and the preschool years. The cons

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Vigdor, Steven E. Water, Water, Here and There. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198814825.003.0004.

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Chapter 4 deals with the stability of the proton, hence of hydrogen, and how to reconcile that stability with the baryon number nonconservation (or baryon conservation) needed to establish a matter–antimatter imbalance in the infant universe. Sakharov’s three conditions for establishing a matter–antimatter imbalance are presented. Grand unified theories and experimental searches for proton decay are described. The concept of spontaneous symmetry breaking is introduced in describing the electroweak phase transition in the infant universe. That transition is treated as the potential site for int

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Burns, Tom, and Mike Firn. Compulsion and freedom. Edited by Tom Burns and Mike Firn. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198754237.003.0008.

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Outreach is particularly needed for patients with limited insight into their need for treatment. This chapter examines the concept of insight and the practices used to support it and to ensure treatment despite its limitations. Balancing individual liberty and recovery against the need for effective treatment is a constant challenge for outreach workers. Internationally, levels of compulsion are increasing. Compulsion has expanded beyond the hospital into the community despite the absence of evidence that such community treatment orders (CTOs) have any significant benefits for patients. Differ

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E. Block, Walter, and Peter L. Nelson. Water Capitalism. Lexington Books, 2015. https://doi.org/10.5040/9781978739918.

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Water covers some 75% of the earth’s surface, while land covers 25%, approximately. Yet the former accounts for less than 1% of world GDP, the latter 99% plus. Part of the reason for this imbalance is that there are more people located on land than water. But a more important explanation is that while land is privately owned, water is unowned (with the exception of a few small lakes and ponds), or governmentally owned (rivers, large lakes). This gives rise to the tragedy of the commons: when something is unowned, people have less of an incentive to care for it, preserve it, and protect it, tha

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De Vries, Catherine E. Euroscepticism and the Future of European Integration. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198793380.001.0001.

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The European Union (EU) is facing one of the rockiest periods in its existence. At no time in its history has it looked so economically fragile, so insecure about how to protect its borders, so divided over how to tackle the crisis of legitimacy facing its institutions, and so under assault by Eurosceptic parties. The unprecedented levels of integration in recent decades have led to increased public contestation, yet at the same the EU is more reliant on public support for its continued legitimacy than ever before. This book examines the role of public opinion in the European integration proce

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Book chapters on the topic "Imbalance of protein"

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Kapoor, Riti Thapar. "Effect of Calcium Silicate Supplementation on the Growth of Trigonella Foenum-Graecum L. Variety Hisar Sonali Under Saline Conditions." In Proceedings of the Conference BioSangam 2022: Emerging Trends in Biotechnology (BIOSANGAM 2022). Atlantis Press International BV, 2022. http://dx.doi.org/10.2991/978-94-6463-020-6_21.

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AbstractSalinity is a major abiotic stress which decreases crop productivity. Salt stress also causes osmotic, water, ionic and oxidative stresses. Plants exposure to salt can check their growth by reduction in water and nutrient uptake, osmotic imbalance and cytotoxicity incited by sodium and chloride ions. Present study deals with the impact of salt on germination, growth and physiological components of fenugreek and its alleviation by the application of calcium silicate. The salt stress reduced fenugreek germination and growth but supplementation of calcium silicate to salt stressed seedlin

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Casini, Alessandro F., Emilia Maellaro, Alfonso Pompella, Marco Ferrali, and Mario Comporti. "Lipid Peroxidation, Protein Thiols, Calcium Homeostasis and Imbalance of Antioxidant Systems in Bromobenzene Induced Liver Damage." In Chemical Carcinogenesis. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4757-9640-7_17.

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Roberts, Sidney. "Effects of Amino Acid Imbalance on Amino Acid Utilization, Protein Synthesis and Polyribosome Function in Cerebral Cortex." In Novartis Foundation Symposia. John Wiley & Sons, Ltd., 2008. http://dx.doi.org/10.1002/9780470720059.ch17.

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Ding, Zejin, and Yan-Qing Zhang. "Review of Imbalanced Data Learning for Protein Methylation Prediction." In Algorithmic and Artificial Intelligence Methods for Protein Bioinformatics. John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118567869.ch4.

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Beigi, Majid, and Andreas Zell. "SPSO: Synthetic Protein Sequence Oversampling for Imbalanced Protein Data and Remote Homology Detection." In Biological and Medical Data Analysis. Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/11946465_10.

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Jung, Jaehee, and Michael R. Thon. "Automatic Annotation of Protein Functional Class from Sparse and Imbalanced Data Sets." In Data Mining and Bioinformatics. Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/11960669_7.

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Palodeto, Viviane, Hernán Terenzi, and Jefferson Luiz Brum Marques. "Training Neural Networks for Protein Secondary Structure Prediction: The Effects of Imbalanced Data Set." In Emerging Intelligent Computing Technology and Applications. With Aspects of Artificial Intelligence. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-04020-7_28.

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Barbot, Michela. "Cedere dei beni al posto del denaro dovuto. La datio in solutum in Francia e Italia fra XVII e XVIII secolo." In Datini Studies in Economic History. Firenze University Press, 2024. http://dx.doi.org/10.36253/979-12-215-0347-0.07.

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This research, which focuses on a comparison between early modern France and Italy, deals with datio in solutum, i.e. the transfer of goods in settlement of a monetary debt. After illustrating its essential features, the text presents the legal interpretations of datio in solutum, analyses its legislative regulation and addresses the well-documented case of the Duchy of Milan. The research shows that the differences between France and Italy reveal two different political attitudes towards debts and obligations: the French one, more inclined to protect the creditor, and the Italian one, more di

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Dundar, Ahmet. "Safety of Food Additives: Sweeteners." In Food Safety. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053358787.2.

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Aspartame, acesulfame K, cyclamate, sucralose, steviol, saccharin, neotame and glycosides are known as artificial sweeteners. Such sweeteners are considered as risk factors in the pathophysiology of many diseases such as obesity, cancer, neurological diseases and cardiovascular diseases. However, the role of artificial sweeteners in the mechanism of action of diseases has not been fully explained. In the pathophysiological mechanism, it has been shown that artificial sweeteners cause oxidative damage, create an imbalance between anti-oxidant and oxidant, and cause health problems by stimulatin

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Kiran, Tugba Raika, and Aysun Bay Karabulut. "Free Radicals and Antioxidants in Diabetics." In Current Multidisciplinary Approach to Diabetes Mellitus Occurrence Mechanism. Nobel Tip Kitabevleri, 2023. http://dx.doi.org/10.69860/nobel.9786053359104.5.

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In diabetics, there is an imbalance between free radicals and antioxidants, leading to oxidative stress, a condition characterized by increased production of reactive oxygen species (ROS) and impaired antioxidant defenses. Free radicals, such as superoxide anion (O2•−), hydroxyl radical (•OH), and hydrogen peroxide (H2O2), are generated as by-products of normal cellular metabolism and play a role in cell signaling and immune response. However, excessive ROS production in diabetes, exacerbated by hyperglycemia and insulin resistance, overwhelms antioxidant defenses, which include enzymatic anti

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Conference papers on the topic "Imbalance of protein"

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Wu, Liwen, Yi Xiang, Yikun Yang, Gang Xue, Shaowen Yao, and Xin Jin. "A Classification Model for Class Imbalance Problem in Protein Subnuclear Localization." In 2018 11th International Congress on Image and Signal Processing, BioMedical Engineering and Informatics (CISP-BMEI). IEEE, 2018. http://dx.doi.org/10.1109/cisp-bmei.2018.8633252.

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Nunes, Ana Katarina Campos, Camila Sinimbú Forte, Arthur Felipe Vasconcelos Ferreira Reis, et al. "Functional Impact Prediction of CFTR Gene Variants in Indigenous Populations of Brazil." In 20º Congresso Brasileiro de Bioinformática: X-Meeting 2024. Even3, 2024. https://doi.org/10.29327/9786527208433.834440.

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Cystic Fibrosis (CF) is a condition resulting from dysfunction in the CFTR protein, leading to a multisystemic disease of ion imbalance that increases the viscosity of mucus produced in epithelial cel

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Stork, Larissa Rosa, Lucca Stephani Ribeiro, Izabella Savergnini Deprá, Luísa D’Ávila Camargo, and Maria Angélica Santos Novaes. "Tau protein and its role in Alzheimer’s disease physiopathology: a literature review." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.132.

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Background: Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by a double proteinopathy: deposition of amyloid-β into plaques and hyperphosphorylation of Tau protein. Objectives: To understand the genetic and molecular aspects of Tau protein and its relationship with Alzheimer’s disease. Methods: We conducted a systematic literature search using Pubmed/ MEDLINE and ClinicalKey databases, applying the descriptors: “Alzheimer Disease” AND “Tau proteins’’ AND Tauopathies, during July and August of 2020. The inclusion criteria were English and Portuguese articles published bet

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Rangarajan, S., P. Londono, C. M. Evans, and V. J. Thannickal. "Mitochondrial Uncoupling Protein-2 Promotes Aerobic Glycolysis and Redox Imbalance in Age-Related Lung Fibrosis." In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5550.

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Bielawiec, M., J. Kloczko, M. Wojtukiewicz, and M. Borowska. "PROTEIN C AND AT III IN ESSENTIAL HYPERTENSION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644257.

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Since hypertension is generally accepted as a risk factor for atherosclerosis and, on the other hand, alterations in haemostasis were reported in the disease, we focused our interest on two plasma inhibitors-protein C and antithrombin III, which play critical roles in the regulation of blood clotting process. We studied 19 patients with newly diagnosed essential hypertension at ist and 2ncl degreeof the disease (acc.to WHO criteria). Protein C antigen level was measured by means of ELISA Protein C test (Boehringer Mannheim GmbH).AT III and Factor VIII R:Ag concentrations were measured by rocke

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Fukui, S., N. Iwamoto, R. Masuyama, K. Kosai, K. Yanagihara, and A. Kawakami. "FRI0017 A novel concept of M1 and M2 monocytes in rheumatoid arthritis: pro-inflammatory monocyte polarization imbalance, anti-citrullinated protein antibody and osteoclastogenesis." In Annual European Congress of Rheumatology, 14–17 June, 2017. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2017-eular.2083.

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Bandeira, Jonathan da Silva, and Roberta Andrade de Araújo Fagundes. "Enhancing Alzheimer’s Disease Diagnosis: Insights from MLP and 1D CNN Models." In Simpósio Brasileiro de Sistemas de Informação. Sociedade Brasileira de Computação, 2025. https://doi.org/10.5753/sbsi.2025.246492.

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Context: Alzheimer’s Disease (AD) is a complex neurodegenerative disorder that requires early diagnosis to improve patient outcomes. Recent advances in computational intelligence have sparked interest in leveraging machine learning to enhance diagnostic accuracy and efficiency. These innovations are crucial for transforming decision-making within Information Systems in clinical settings. Problem: Traditional methods like PET-scans and cerebrospinal fluid collection are highly accurate but costly and invasive, limiting accessibility. Developing data-driven, non-invasive solutions that retain di

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Hatami-Marbini, Hamed, Ebitimi Etebu, and Abdolrasol Rahimi. "Characterizing Swelling Pressure and Hydration Relationship for Porcine Corneal Stroma." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14759.

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The mechanical properties and structure of connective tissues such as the cornea and articular cartilage are derived from the functions and properties of their extracellular matrix, which is a polyelectrolyte gel composed of collagenous fibers embedded in an aqueous matrix. The collagen fibrils in the extracellular matrix of the corneal stroma are arranged in a regular lattice structure, which is necessary for corneal transparency and transmitting the incident light to the back of the eye. This regular pseudo hexagonal arrangement is attributed to the interaction of collagen fibrils with the p

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Šarac, Ivana. "The basic principles of diet therapy in the treatment of patients with associated heart and kidney diseases." In 7th International Congress of Cardionephrology KARNEF 2025. Punta Niš, 2025. https://doi.org/10.46793/karnef25.231s.

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The relationship between chronic kidney disease (CKD) and cardiovascular disease (CVD) is extensively documented in the literature. Patients with CKD exhibit an elevated cardiovascular risk, often presenting edema, imbalance in electrolytes, proteins, lipoproteins, hormones (including vitamin D, parathormone, renin-angiotensin-aldosterone system), enzymes, growth factors, cytokines, endothelial dysfunction, inflammation, oxidative stress, insulin resistance, and anemia, leading to cardiovascular remodeling. This results in hypertension, arteriosclerosis, arterial and cardiac valve calcificatio

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Kwon, E., H. K. Min, M. Y. Kim, et al. "FRI0151 Protein inhibitor of activated stat3 prevents peripheral arthritis and gut inflammation by regulating th17/treg cell imbalance via stat3 signalling in mice model of spondyloarthritis." In Annual European Congress of Rheumatology, EULAR 2018, Amsterdam, 13–16 June 2018. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. http://dx.doi.org/10.1136/annrheumdis-2018-eular.1824.

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Reports on the topic "Imbalance of protein"

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Lurie, Susan, John Labavitch, Ruth Ben-Arie, and Ken Shackel. Woolliness in Peaches and Nectarines. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7570557.bard.

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The overall goal of the research was to understand the processes involved in the development of woolliness in peaches and nectarines. Four specific hypotheses were proposed and in the course of the research evidence was gathered t support two of them and to not support two others. The hypotheses and a summary of the evidence are outlined below. 1. That woolliness arises from an imbalance between the activities of the cell wall pectin degrading enzymes. Using 'Flavortop' nectarines and 'Hermoza' peaches as model systems, storage regimes were manipulated to induce or prevent woolliness. The expr

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Diokno-Sicat, Charlotte Justine, Angel Faye Castillo, and Ricxie Maddawin. Philippine Local Government Public Expenditure Review: A Survey of National Government Local Government Support Programs. Philippine Institute for Development Studies, 2020. https://doi.org/10.62986/dp2020.48.

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Philippine local governments were given increased autonomy, revenue-raising and expenditure responsibilities under the Local Government Code of 1991 (LGC). At the same time, the LGC instituted the intergovernmental fiscal transfer called the internal revenue allotment (IRA) to help to help local governments fulfill their mandates recognizing fiscal imbalance in devolved functions. Apart from this, national government provides additional assistance to local governments through programs lodged in different agencies that are meant for devolved infrastructure services. This study examines these na

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Bhutiani, Rakesh. Environmental Justice and Policy: A Global Imperative for a Fairer, Greener Future: An Urgent need 2025. Rakesh Bhutiani, 2025. https://doi.org/10.36953/rbb.13072025.

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“Environmental justice is not just about the environment-it about people. It’s about dignity. It’s about equity.” The damage we do to the planet does not land evenly. Dark smoke hangs over busy, low-income neighbourhoods, while coastlines that poor island families call home slowly slip below wave after wave. Too often, those who did the least to cause the problem feel the blow first and hardest. That imbalance sits at the heart of environmental justice. It says that caring for nature and caring for people must walk hand in hand. When a new mine opens, a highway stretches through a community, o

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Ocampo-Gaviria, José Antonio, Roberto Steiner Sampedro, Mauricio Villamizar Villegas, et al. Report of the Board of Directors to the Congress of Colombia - March 2023. Banco de la República de Colombia, 2023. http://dx.doi.org/10.32468/inf-jun-dir-con-rep-eng.03-2023.

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Banco de la República is celebrating its 100th anniversary in 2023. This is a very significant anniversary and one that provides an opportunity to highlight the contribution the Bank has made to the country’s development. Its track record as guarantor of monetary stability has established it as the one independent state institution that generates the greatest confidence among Colombians due to its transparency, management capabilities, and effective compliance with the central banking and cultural responsibilities entrusted to it by the Constitution and the Law. On a date as important as this,

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