Relevant bibliographies by topics / IMCR

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
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Academic literature on the topic 'IMCR'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 June 2024

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Journal articles on the topic "IMCR"

1

Sun, Zimin, Huilan Liu, Yue Wu, Changcheng Zheng, Baolin Tang, Xiaoyu Zhu, and Qifa Liu. "Intensified Myeloablative Conditioning Regimen without Antithymocytic (ATG) Results in Superior Patient Outcome Compared to Myeloablative Conditioning Regimen for Single-Unit Umbilical Cord Blood Transplantation in Hematological Malignancies." Blood 128, no. 22 (December 2, 2016): 5837. http://dx.doi.org/10.1182/blood.v128.22.5837.5837.

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Abstract The superiority and safety of strengthening conditioning regimen for single- unit unrelated cord blood transplantation (sUCBT) in hematological malignancies remain controversial. We retrospectively analyzed the clinical data of 251 hematological malignancies undergoing sUCBT from Apr 2000 to Dec 2014 at Department of hematology in Anhui Provincial Hospital. Out of the 251 patients, 216 received the intensified myeloablative conditioning regimen (IMCR), and 35 received the myeloablative conditioning regimen (MCR). We evaluated the effect of IMCR without using Antithymocyte globulin (ATG) on patient outcomes. The cumulative incidence of myeloid and platelet engraftment of the IMCR group was significantly higher than that in the MCR group (96.98% vs. 82.81%, 85.89% vs. 51.79%, P=0.000 and 0.003, respectively). Corresponding incidences of transplantation-related mortality (TRM) by 180 days in the IMCR group and the MCR group were 19.50% vs. 41.67% (P=0.003), respectively. There were no differences in the incidence of grade II to IV acute GVHD (aGVDH), grade III to IV aGVHD and 2-year cumulative incidence of relapse. Up to Dec. 2015, with a median follow-up of 30 months, the estimated 3-year overall survival and disease- free survival in the IMCR group were both significantly higher than that of the MCR group (64.8% vs. 35.5%, 61.6% vs. 35.5%, P=0.000 and 0.001, respectively). This study is the first to show the superiority of intensified myeloablative regimen to conventional myeloablative regimen.A large-scale prospective study was needed. (A) (B) Figure 1 The cumulative incidence of neutrophil and platelet engraftment of the IMCR group and MCR group. (A)The cumulative incidence of neutrophil engraftment of the IMCR group was predominantly higher than that in the MCR group(96.98% vs. 82.81%, P=0.000). (B)The cumulative incidence of platelet engraftment of the IMCR group was also higher than that in the MCR group(85.89% vs. 51.79%, P=0.003). Figure 1. The cumulative incidence of neutrophil and platelet engraftment of the IMCR group and MCR group. (A)The cumulative incidence of neutrophil engraftment of the IMCR group was predominantly higher than that in the MCR group(96.98% vs. 82.81%, P=0.000). (B)The cumulative incidence of platelet engraftment of the IMCR group was also higher than that in the MCR group(85.89% vs. 51.79%, P=0.003). Figure 2 Comparison of the incidence of 3-year OS between the IMCR group and the MCR group.The incidence of 3-year OS of the IMCR group is predominantly higher than that of the MCR group(62.4% vs. 35.5%,P=0.001). Figure 2. Comparison of the incidence of 3-year OS between the IMCR group and the MCR group.The incidence of 3-year OS of the IMCR group is predominantly higher than that of the MCR group(62.4% vs. 35.5%,P=0.001). Figure 3 Figure 3. Disclosures No relevant conflicts of interest to declare.
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Ssatar, Ibdal, Mohd Nur Ikhmal Salehmin, Mimi Hani Abu Bakar, Wan Ramli Wan Daud, Ika Dyah Kumalasari, Muhammad Aziz, Mahendara Rao Somalu, and Byung Hong Kim. "Evaluating hydrogen production from glucose using graphite felt beads as a solid matrix in immobilized mixed cell reactor at thermophilic fermentation." Communications in Science and Technology 8, no. 2 (December 31, 2023): 180–89. http://dx.doi.org/10.21924/cst.8.2.2023.1238.

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This study has successfully evaluated graphite felt (GF) beads as a solid matrix to immobilize or trap the mixed cultures in an immobilized mixed-cell reactor (IMcR). The anaerobic sludge of palm oil mill effluent was used as an inoculum source in the IMcR with mixed culture. Here, glucose, sucrose, and starch were used as the model substrates to evaluate the performance of IMcR with GF beads for producing bio-hydrogen (BioH2). BioH2, effluent, and surface morphology of GF beads were analyzed by using gas chromatography equipped with a thermal conductivity detector, high-performance liquid chromatography, and scanning electron microscopy, respectively. The highest H2 yield (YH2) and production rates were obtained at 304.0 ± 13.2 mL g?1COD (corresponding to 2.26 mol mol?1glucose) and 1403 ± 61 mL L?1 day?1, respectively. IMcR with GF beads is a new approach for generating high YH2, which can be used for more than two months in an experimental run.
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Ramírez-López, Sandra C., Manuel Alejandro Rentería-Gómez, Cesar R. Solorio Alvarado, and Rocío Gámez-Montaño. "Synthesis of Peptidomimetics via IMCR/Post-Transformation Strategy." Chemistry Proceedings 3, no. 1 (November 14, 2020): 4. http://dx.doi.org/10.3390/ecsoc-24-08396.

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A series of three 2,5-Diketopiperazine (DKPs) were synthesized via one-pot process through the post- isocyanide-based multicomponent reactions (IMCR)-transformation strategy. This strategy emphasizes the role of orthogonal bifunctional reagents in the IMCR process to increase their synthetic potential, allowing us accessing a synthetic platform from which it is possible to obtain privileged heterocyclic peptidomimetics via lactamization reaction.
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Koopmanschap, Gijs, Eelco Ruijter, and Romano VA Orru. "Isocyanide-based multicomponent reactions towards cyclic constrained peptidomimetics." Beilstein Journal of Organic Chemistry 10 (March 4, 2014): 544–98. http://dx.doi.org/10.3762/bjoc.10.50.

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In the recent past, the design and synthesis of peptide mimics (peptidomimetics) has received much attention. This because they have shown in many cases enhanced pharmacological properties over their natural peptide analogues. In particular, the incorporation of cyclic constructs into peptides is of high interest as they reduce the flexibility of the peptide enhancing often affinity for a certain receptor. Moreover, these cyclic mimics force the molecule into a well-defined secondary structure. Constraint structural and conformational features are often found in biological active peptides. For the synthesis of cyclic constrained peptidomimetics usually a sequence of multiple reactions has been applied, which makes it difficult to easily introduce structural diversity necessary for fine tuning the biological activity. A promising approach to tackle this problem is the use of multicomponent reactions (MCRs), because they can introduce both structural diversity and molecular complexity in only one step. Among the MCRs, the isocyanide-based multicomponent reactions (IMCRs) are most relevant for the synthesis of peptidomimetics because they provide peptide-like products. However, these IMCRs usually give linear products and in order to obtain cyclic constrained peptidomimetics, the acyclic products have to be cyclized via additional cyclization strategies. This is possible via incorporation of bifunctional substrates into the initial IMCR. Examples of such bifunctional groups are N-protected amino acids, convertible isocyanides or MCR-components that bear an additional alkene, alkyne or azide moiety and can be cyclized via either a deprotection–cyclization strategy, a ring-closing metathesis, a 1,3-dipolar cycloaddition or even via a sequence of multiple multicomponent reactions. The sequential IMCR-cyclization reactions can afford small cyclic peptide mimics (ranging from four- to seven-membered rings), medium-sized cyclic constructs or peptidic macrocycles (>12 membered rings). This review describes the developments since 2002 of IMCRs-cyclization strategies towards a wide variety of small cyclic mimics, medium sized cyclic constructs and macrocyclic peptidomimetics.
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Mota Palma, Jaqueline, Norma Ivonne González-Arratia López-Fuentes, José Luis Valdez Medina, Sergio González Escobar, and Gabriela Hernández Vergara. "Construcción y Análisis Estadístico del Inventario Multidimensional de Celos Románticos: Estudio Preliminar." Actualidades en Psicología 30, no. 120 (June 27, 2016): 31. http://dx.doi.org/10.15517/ap.v30i120.18977.

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<div class="page" title="Page 1"><div class="section"><div class="layoutArea"><div class="column"><p>Con el objetivo de construir y validar una prueba para medir propiedades de los celos románticos, se desarrolló el Inventario Multidimensional de Celos Románticos (IMCR) desde tres ejes: 1) su conceptualización, 2) circunstancias que lo generan y 3) respuestas cognitivas, afectivas y conductuales involucradas. El IMCR está constituido por cinco escalas tipo Likert con sus respectivas opciones de respuesta. Se acudió a juicio de expertos para la validez de contenido y por análisis factoriales exploratorios para la validez de constructo de cada escala, presentando coeficientes de confiabilidad superiores a (α &gt; .873). Por esto, el IMCR tiene una estructura relativamente clara con dimensiones en parte independientes y que miden con razonable precisión los tres ejes; concluyendo que los celos románticos son un constructo multidimensional con respuestas afectivas, cognitivas y conductuales desencadenadas a partir de una situación que representa la posible pérdida de la pareja.</p></div></div></div></div>
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Archilla, Ivan, Leire Pedrosa, Marta Garcia de Herreros, Laia Fernandez-Mañas, Francis Esposito, Pedro Jares, Carolina Figueras, et al. "An Immune-metabolic signature (IMMETCOLS) identifies three clusters in mCRC with different immune-phenotype distribution and potential clinical implications." Journal of Clinical Oncology 40, no. 16_suppl (June 1, 2022): e15534-e15534. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.e15534.

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e15534 Background: The overall response rate following immune check-point blockade (ICB) is < 5% in microsatellite stable (MSS) advanced colorectal cancer (mCRC), and between 30-35% in MSI mCRC. We here evaluate the relationship between our immune-metabolic signature (IMMETCOLS) distribution (cluster (IMC) 1; mesenchymal glycolytic, IMC 2; epithelial-non glycolytic and IMC 3; epithelial mitochondrial oxidative) with immune phenotypes (inflamed (IF), immune-excluded (IE) and immune-desert (ID)) in MSS and MSI mCRC patients (pts). Methods: We have analyzed IMMETCOLS in a retrospective cohort of 128 mCRC pts enriched with MSI-H and BRAF genotype using the nCounter platform (Nanostring Technologies, US). Immune phenotypes were evaluated by immunohistochemistry using 7 immune markers (CD68, CD163, CD8, CD3, FOXP3, PD-L1 and PD1) in a subset of 47 mCRC pts (27 MSS and 20 MSI), in TMAs containing 4 cores from the center of the tumor (CT) and invasive front (IF). The number of stained immune cells was counted using a computerized image analysis system, and PD-L1 was evaluated using CPS score (< 1 vs > 1). Patients having a CD3 cell count below 572 cells/mm2 and a CD8 density below 175 cells/mm2 in IF or CT were considered as ID. (Halama Nils, 2011). CD3 density was also semi-quantitatively estimated in peritumoral stroma and intra-tumoral (range 1-4), defining as IE those cases with a difference > 1 between the two regions in both IF and CT (Brooks JM, 2019). Results: Cluster distribution was similar between MSI (IMC1-40%, IMC2-20% and IMC-40%) and MSS (IMC1-34%, IMC2-24%, IMC3-43%) pts. Patients with high LDH levels (> 1.5ULN) were enriched with IMC3 phenotype (p < 0.0001). MSI have increased CD3 (p = 0.002), CD68 (p = 0.002) and CD163 (p = 0.001) in CT than MSS patients. IMC1 pts had increased CD163/CD68 ratio in CT (p = 0.004). 75% of MSI pts were IE and 25% IF. 55% of MSS pts were IE, 38% ID and 7% IF. IMMETCOLS/ immune-phenotype distribution was: IMC1 (16% ID/ 84% IE), IMC2 (12% ID/ 63% IE/ 25% IF) and IMC3 (35%ID/ 47% IE/ 18% IF). PD1 immuno-expression > 1% (IF and CT) and PD-L1 positivity was observed in 38%, 30% and 28% of pts respectively. There were no differences in PD-L1 (CPS) and PD1 expression between MSS and MSI tumors. Inflamed tumors show higher PD-L1 expression compared with IE and ID immune-phenotypes (p = 0.014). PD1 > 1% expression at IF was significatively lower in IMC1 vs IMC2 and IMC3 tumors (p = 0.032). Conclusions: IMC1 subtype is associated with low PD1 expression, high CD163/CD68 ratio and IE phenotype even in MSI-H mCRC patients. Therefore, IMMETCOLS testing would be of value to identify MSI mCRC pts that do not benefit to ICB therapy.
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Torres-Hernández, Fernando, Ángel Rentería-Gómez, and Rocío Gámez-Montaño. "Synthesis of Epoxyisoindolinones via Microwave-Assisted Ugi-4CR/Intramolecular-Diels-Alder Reaction." Cells 3, no. 1 (November 14, 2020): 83. http://dx.doi.org/10.3390/ecsoc-24-08425.

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A series of epoxyisoindolinones were synthesized by microwave-assisted post-IMCR transformation-based domino strategy via the Ugi-4CR/Intramolecular-Diels-Alder (U-4CR/IMDA) sequence under mild, solvent-, catalyst-free ecofriendly conditions, and orthogonal-bifunctional components. Epoxyisoindolinones are a privileged core of high interest in medicinal chemistry mainly for its anticancer activity in several cell lines.
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Ramírez-López, Sandra C., Àngel Rentería-Gómez, Luis E. Cárdenas Galindo, and Rocío Gámez-Montaño. "Synthesis of Tetrakis-Tetrazole via a Repetitive MCR." Chemistry Proceedings 3, no. 1 (November 14, 2020): 44. http://dx.doi.org/10.3390/ecsoc-24-08395.

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The synthesis of novel and complex molecules of tetrakis-tetrazole was done via a Ugi-azide repetitive reaction from easily accessible starting materials in good yields. The use of orthogonal bifunctional reagents in isocyanide-based multicomponent reactions (IMCR) allowed the synthesis of structurally complex molecules in one pot manner. The molecules herein synthesized could have applications such as use as chelating agents and organocatalysts.
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Rentería-Gómez, Manuel A., Tannya R. Ibarra-Rivera, and Rocío Gámez-Montaño. "A One-Pot Synthesis of Fluoro α-Acylamino Amide-Xanthates via an IMCR-Post Transformation Strategy." Chemistry Proceedings 3, no. 1 (November 14, 2020): 59. http://dx.doi.org/10.3390/ecsoc-24-08421.

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A series of six novel amide-xanthate products containing several fluorine atoms were prepared in moderate to good yields (40–92%) via an isocyanide-based multicomponent reaction (IMCR) of 5-CR by Ugi-4CR followed by an SN2 sequence in a one-pot manner. The design of molecules with fluorine atoms is of interest in medicinal chemistry and a research line of our interest. The role of fluorine atoms in biological properties is well documented, improving bioavailability, lipophilicity, and metabolic resistance in bioactive molecules.
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Ramírez-López, Sandra C., M. V. Basavanag Unnamatla, and Rocío Gámez-Montaño. "A One-Pot Process for the Synthesis of Alkyne-3-tretrazolyl-tetrazolo [1,5-a] Quinolines." Proceedings 9, no. 1 (November 14, 2018): 42. http://dx.doi.org/10.3390/ecsoc-22-05798.

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An efficient synthesis of alkyne-3-tetrazolyl-tetrazolo[1,5-a] quinolones via a one-pot isocyanide-based multicomponent reaction (IMCR) process: I-MCR Ugi-azide/SNAr/ring-chain azido tautomerization was performed under eco-friendly conditions. We report the one-pot synthesis of tris-heterocycles containing a tetrazolo[1,5-a] quinoline connected to a 1,5-disubstituted-tetrazole (1,5-DS-T). The synthesis of these compounds is of great interest in synthetic and medicinal chemistry because these heterocycles are considered privileged scaffolds and their preparation and evaluation may lead to the discovery of novel bioactive molecules.
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Dissertations / Theses on the topic "IMCR"

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Narboni, Claude. "Réactions multi composants et essais d’accès à de nouveaux pentazoles." Thesis, Université Paris-Saclay (ComUE), 2017. http://www.theses.fr/2017SACLY008.

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Ces travaux proposent d'explorer lachimie de l'azote, de la synthèse de moléculespauvres en azote à visée biologique à lasynthèse de molécules très riches en azote papplication en propulsion.La première partie porte sur la synthèse demolécules contenant peu d'azote. Le but est decompléter les bibliothèques de réactionsdisponibles pour la synthèse de moléculesnaturelle ou à forte activité biologique. Pour cefaire, les réactions multicomposants mettant enjeu des isonitriles sont des outils de choix : ellespermettent d'obtenir des structures complexesen très peu d'étapes. Nous avons testé diversnucléophiles dans une séquence réactionnellePasserini / Tsuji-Trost suivie de différentespost-condensations. Nous avons ainsi pu obtenirdes molécules aussi variées que des lactames,des diènes, des cyclopentanes, descyclopentènes ou encore des pyrroles.La seconde partie se concentre sur de nouvellesmolécules énergétiques très riches en azoNous nous sommes intéressés au pentazoles,avenir des HEDM. La modélisation desmolécules cibles nous a permis de sélectionnerales plus prometteuses et de tester leur faisabilitéen synthèse
This work proposes to explore thechemistry of nitrogen, from the synthesis oflow-in-nitrogen molecules with potentialbiological activity to the synthesis of veryhigh-in-nitrogen molecules for application inpropulsion.The first part deals with the synthesis ofmolecules containing little nitrogen. The aim isto supplement the library of reactions availablefor the synthesis of natural molecules ormolecules with biological activity. To achievethis, multicomponent reactions involvingisonitriles are tools of choice: they enablesynthesis of complex structures in very fewsteps. We tested various nucleophiles in aPasserini / Tsuji-Trost reaction sequencefollowed by different post-condensations. Wehave thus been able to obtain molecules asvaried as lactams, dienes, cyclopentanes,cyclopentenes or even pyrroles.The second part focuses on new energymolecules rich in nitrogen. We were interestedin pentazoles, the future of HEDM. Themodeling of the target molecules allowed us toselect the most promising ones, to then testtheir feasibility in synthesis
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Narboni, Claude. "Réactions multi composants et essais d’accès à de nouveaux pentazoles." Electronic Thesis or Diss., Université Paris-Saclay (ComUE), 2017. http://www.theses.fr/2017SACLY008.

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Ces travaux proposent d'explorer lachimie de l'azote, de la synthèse de moléculespauvres en azote à visée biologique à lasynthèse de molécules très riches en azote papplication en propulsion.La première partie porte sur la synthèse demolécules contenant peu d'azote. Le but est decompléter les bibliothèques de réactionsdisponibles pour la synthèse de moléculesnaturelle ou à forte activité biologique. Pour cefaire, les réactions multicomposants mettant enjeu des isonitriles sont des outils de choix : ellespermettent d'obtenir des structures complexesen très peu d'étapes. Nous avons testé diversnucléophiles dans une séquence réactionnellePasserini / Tsuji-Trost suivie de différentespost-condensations. Nous avons ainsi pu obtenirdes molécules aussi variées que des lactames,des diènes, des cyclopentanes, descyclopentènes ou encore des pyrroles.La seconde partie se concentre sur de nouvellesmolécules énergétiques très riches en azoNous nous sommes intéressés au pentazoles,avenir des HEDM. La modélisation desmolécules cibles nous a permis de sélectionnerales plus prometteuses et de tester leur faisabilitéen synthèse
This work proposes to explore thechemistry of nitrogen, from the synthesis oflow-in-nitrogen molecules with potentialbiological activity to the synthesis of veryhigh-in-nitrogen molecules for application inpropulsion.The first part deals with the synthesis ofmolecules containing little nitrogen. The aim isto supplement the library of reactions availablefor the synthesis of natural molecules ormolecules with biological activity. To achievethis, multicomponent reactions involvingisonitriles are tools of choice: they enablesynthesis of complex structures in very fewsteps. We tested various nucleophiles in aPasserini / Tsuji-Trost reaction sequencefollowed by different post-condensations. Wehave thus been able to obtain molecules asvaried as lactams, dienes, cyclopentanes,cyclopentenes or even pyrroles.The second part focuses on new energymolecules rich in nitrogen. We were interestedin pentazoles, the future of HEDM. Themodeling of the target molecules allowed us toselect the most promising ones, to then testtheir feasibility in synthesis
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Patil, Pravin. "Des réactions multicomposants impliquant des isonitriles a la synthèse d'heterocycles." Phd thesis, Ecole Polytechnique X, 2012. http://pastel.archives-ouvertes.fr/pastel-00739959.

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Ces travaux mettent en valeur les réactions multicomposants a base d'isonitriles dans différentes applications autour des réactions d'Ugi-Smiles et de Nef pour la synthèse de systèmes hétérocycliques complexes. Nous avons démontré la possibilité d'utiliser des 4-hydroxypyridine et pyrimidines dans des couplages Ugi-Smiles. Ces réactions ont été appliquées à la préparation d'analogues d'antipaludéens. Diverses applications radicalaires ont été explorées sur des adduits de Ugi et Ugi-Smiles ( chimie des xanthates, couplages oxydatifs d'indoles). Nous avons par ailleurs exploré la chimie des dihalogénoisonitriles dans différentes synthèses hétérocycliques.
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Števanka, Kamil. "Koncepce výměníku pro IMSR reaktor." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2017. http://www.nusl.cz/ntk/nusl-318093.

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Cílem práce bylo vytvořit základní koncept integrovaného výměníku tepla pro solí chlazený reaktor vyvíjený společností Terrestrial Energy s využitím programu Promex. První kapitola se zabývá historií a současnou situací v oblasti výzkumu malých modulárních reaktorů chlazených fluoridovými solemi. Ve druhé kapitole jsou popsány vlastnosti fluoridových solí a konstrukčních materiálů. Poslední kapitola se zabývá simulací tepelného výměníku pomocí programu Promex, validací modelu, transformací protiproudého výměníku na výměník s U trubkami a vizualizací výměníku s použitím CAD Invetoru.
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Makri, Aikaterini, Karolos-Konstantinos Papadas, and Bodo B. Schlegelmilch. "Global-local consumer identities as drivers of global digital brand usage." Emerald Publishing Limited, 2018. http://dx.doi.org/10.1108/IMR-03-2018-0104.

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Purpose: The purpose of this paper is to represent the first empirical attempt to explore global-local consumer identities as drivers of global digital brand usage. Specifically, this study considers a unique category of digital products, social networking sites (SNS), and develops a set of hypotheses to assess the mechanism through which location-based identities influence the actual usage of global SNS (Facebook and Instagram). Moreover, cross-country variations are investigated under the lens of developed vs developing countries. Design/methodology/Approach: Cross-country surveys in a developed (Austria) and a developing country (Thailand) were conducted. Data collected from 425 young adults were analyzed using SEM techniques in order to test a set of hypotheses. Findings: Results show that in Thailand, users with a global identity enjoy participating in global SNS more than their counterparts in Austria. In addition, consumers with a local identity in Thailand demonstrate less pleasure when participating in global SNS than their counterparts in Austria, and consequently are less inclined to use global SNS. Practical implications: Findings provide digital marketers with useful insights into important strategic decisions regarding the selection and potential adaptation of global digital brands according to the country context. Originality/value: This research is the first to extend the location-based identity research in the context of global digital brands, explain how global-local identities predict SNS usage through an engagement mechanism and investigate cross-country variations of this mechanism.
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Bamford, Lesley Jean. "Implementing IMCI supervision in South Africa." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.409351.

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Kumar, Chandan. "Modelling intermittent microwave convective drying (IMCD) of food materials." Thesis, Queensland University of Technology, 2015. https://eprints.qut.edu.au/85437/1/CHANDAN_KUMAR_Thesis.pdf.

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This thesis develops comprehensive mathematical models for an advanced drying technology Intermittent Microwave Convective Drying (IMCD). The models provide an improved physical understanding of the heat and mass transport during the drying process, which will help to improve the quality of dried food and energy efficiency of the process, as well as will increase the ability of automation and optimization. The final model in this thesis represents the most comprehensive fundamental multiphase model for IMCD that considers 3D electromagnetics coupled with multiphase porous media transport processes. The 3D electromagnetics considers Maxwell's equation and multiphase transport model considers three different phases: solid matrix, liquid water and gas consisting water vapour and air. The multiphase transport includes pressure-driven flow, capillary diffusion, binary diffusion, and evaporation. The models developed in this thesis were validated with extensive experimental investigations.
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Pete, Thobeka Portia. "Deformation processed IMC-reinforced metal matrix composites." Thesis, This resource online, 1994. http://scholar.lib.vt.edu/theses/available/etd-07112009-040418/.

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Mayombana, Charles Chrisostom. "Local understanding and practices related to IMCI interventions in eastern Tanzania." Basel : [s.n.], 2005. http://edoc.unibas.ch/diss/DissB_7175.

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Černý, Martin. "Konstrukční návrh uložení měřící aparatury IMC ve vozidle." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2018. http://www.nusl.cz/ntk/nusl-377458.

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Devices for measuring the dynamic load and vibration of certain parts of the bodywork or parts of other parts of the vehicle are made using accelerometers and measuring instruments IMC. It must be simply installed into the interior of the vehicle so that it is not necessary to remove any parts of the interior and to avoid damage to all parts of the interior. The preparation must also withstand the considerable dynamic load generated by the harder operation tests.
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Books on the topic "IMCR"

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Durchholz, Reiner. Compositional data objects: The IMC/IMCL reference manual. Chichester: Wiley, 1992.

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Kağıthane: Imar planı araştırmaları. İstanbul: Kağıthane Belediyesi Başkanlığı, 2013.

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Yalçın, Azmi. Kurumsal itibar ve imar. Ankara: Akademisyen Kitabevi, 2018.

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Steve, Smith. Racing the IMCA modified. Santa Ana, CA: Steve Smith Autosports, 1992.

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Hossain, Md Monjur. Community IMCI strategy in Bangladesh. Dhaka: IMCI National Working Group, Directorate General of Health Services, Ministry of Health and Family Welfare, 2004.

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Hossain, Md Monjur. Community IMCI strategy in Bangladesh. Dhaka: IMCI National Working Group, Directorate General of Health Services, Ministry of Health and Family Welfare, 2004.

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Çeçener, Besim. İstanbul'un kültür ve imar sorunları. İstanbul: Mimarlar Odası, İstanbul Büyükkent Şubesi, 1995.

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Osmanlıdan günümüze imar ve yasalar. Sarıyer, İstanbul: Ninova Yayınları, 2017.

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Council, International Code. IMC fundamentals, 2003. International Code Council: Falls Church, VA, 2004.

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Council, International Code, ed. 2003 IMC fundamentals. Falls Church, VA: International Code Council, 2003.

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Book chapters on the topic "IMCR"

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Dandia, Anshu, Shahnawaz Khan, Vijay Parewa, Amit Sharma, and Begraj Kumawat. "Modern Synthesis of Bioactive Heterocycles via IMCR Modification." In Multicomponent Reactions, 229–80. Boca Raton : CRC Press, 2017.: CRC Press, 2017. http://dx.doi.org/10.1201/9781315369754-9.

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Arroyo, Ignacio. "IMC." In Yearbook Maritime Law, 351–54. Dordrecht: Springer Netherlands, 1986. http://dx.doi.org/10.1007/978-94-017-3707-4_30.

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Mehlhorn, Heinz. "IMC." In Encyclopedia of Parasitology, 1325. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-43978-4_3963.

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Mehlhorn, Heinz. "IMC." In Encyclopedia of Parasitology, 1. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27769-6_3963-1.

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Eagle, Lynne, Barbara Czarnecka, Stephan Dahl, and Jenny Lloyd. "IMC and branding." In Marketing Communications, 143–64. Second edition. | Abingdon, Oxon; New York, NY: Routledge, 2021.: Routledge, 2020. http://dx.doi.org/10.4324/9781003089292-7.

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Percy, Larry. "Brands and IMC." In Strategic Integrated Marketing Communications, 20–38. 4th ed. London: Routledge, 2023. http://dx.doi.org/10.4324/9781003169635-3.

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Percy, Larry. "Overview of IMC." In Strategic Integrated Marketing Communications, 3–19. 4th ed. London: Routledge, 2023. http://dx.doi.org/10.4324/9781003169635-2.

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Percy, Larry. "Companies and IMC." In Strategic Integrated Marketing Communications, 39–61. 4th ed. London: Routledge, 2023. http://dx.doi.org/10.4324/9781003169635-4.

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Kitchen, Philip J. "Is IMC “Marketing Oriented”?" In Rediscovering the Essentiality of Marketing, 441–42. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29877-1_92.

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Søilen, Klaus Solberg. "Integrated Marketing Communications (IMC)." In Management for Professionals, 1–13. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-36793-9_1.

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Conference papers on the topic "IMCR"

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Wang, Chengcheng, Xingjian Ma, Wenwen Jiang, Liang Zhao, Na Lin, and Junling Shi. "IMCR: Influence Maximisation-Based Cluster Routing Algorithm for SDVN." In 2019 IEEE 21st International Conference on High Performance Computing and Communications; IEEE 17th International Conference on Smart City; IEEE 5th International Conference on Data Science and Systems (HPCC/SmartCity/DSS). IEEE, 2019. http://dx.doi.org/10.1109/hpcc/smartcity/dss.2019.00361.

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Chauhan, Preeti, Michael Osterman, and Michael Pecht. "Impact of Thermal Aging on the Growth of Cu-Sn Intermetallic Compounds in Pb-Free Solder Joints in 2512 Resistors." In ASME 2009 International Mechanical Engineering Congress and Exposition. ASMEDC, 2009. http://dx.doi.org/10.1115/imece2009-10169.

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Interfacial intermetallic compounds (IMCs) in solder joints are formed during soldering and continue to grow after assembly. Excessive interfacial IMC growth may impact the reliability of solder interconnections due to changes in material behavior. The impact of thermal aging on IMC growth can be determined by subjecting assemblies to elevated temperatures and determining the interfacial IMC growth. This paper discusses the interfacial IMCs formed in the solder-Cu interface for SAC305, SAC105, and Sn-0.7Cu-0.05Ni+Ge (SN100C) assemblies. Test assemblies were produced using tin-finished 2512 resistors soldered onto OSP-finished copper lands. The assemblies were subjected to aging conditions of 100°C for 24 h and 600 h; and 150°C for 24 h and the impact of high temperature aging on the thickness of IMCs formed at solder-Cu interface was studied. Samples stored at room temperature for 600 h were the reference specimen for the experiment. The IMC growth observed in the lead-free solders was compared with that in eutectic SnPb. Interfacial IMCs formed in room temperature conditioned specimens were scallop shaped and non-uniform. The IMC structure evolved with aging temperature and duration resulting in smoother and more uniform IMCs in 100°C/600 h aged samples. A comparison of IMC thickness in the solders at given aging conditions revealed that SAC305 exhibited highest IMC thickness, followed by SAC105 and SN100C. SnPb showed the least IMC thickness at all aging conditions except at 150°C for 24 h. At this condition, SnPb showed IMC thickness comparable to SAC305 solder and was higher than other solders.
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Pimenta, Marcelo Soares, and Carlos Alberto Heuser. "Uma formalização em IMC: o modelo DODM." In Simpósio Brasileiro de Engenharia de Software. Sociedade Brasileira de Computação, 1989. http://dx.doi.org/10.5753/sbes.1989.25268.

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O trabalho apresenta a descrição formal dos tipos de objetos do DODM, o modelo de dados do SGBD orientado à engenharia de software DAMOKLES, usando a abordagem de formalização IMC (Information Modeling by Composition) e a respectiva linguagem IMCL. A intenção é permitir uma melhor compreensão do DODM, bem como testar a aplicabilidade de IMC a casos reais.
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Pang, John H. L., and Luhua Xu. "Board-Level Drop Reliability Performance Before and After Thermal Cycling Aging." In ASME 2007 InterPACK Conference collocated with the ASME/JSME 2007 Thermal Engineering Heat Transfer Summer Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/ipack2007-33738.

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The combined sequential reliability test of thermal cycling aging followed by board level drop test for lead-free SnAgCu soldered assemblies were investigated. Interfacial IMCs, Kirkendall voids formation and interconnect failure mode are studied subject to TC aging. Kirkendall voids were observed with Ar+ sputtering etching. The failure sites and mechanism were examined and correlated with IMC and void formation. Significant decrease of drop life was observed for both SAC/ENIG and SAC/Cu-OSP assemblies after thermal cycling aging. Growth of Kirkendall voids and IMC significantly weakened the solder joint interface during TC aging. Drop impact crack path changed from the IMC to the IMC/Cu interface.
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Choudhury, Soud Farhan, and Leila Ladani. "Anisotropic Behavior of Single Grain Cu6Sn5 Intermetallic." In ASME 2014 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/imece2014-40196.

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Intermetallic (IMC) layers (Cu6Sn5 and Cu3Sn) are an essential component of a solder joint for good metallurgical bonding. However, the mechanical and physical properties of IMC layers differ significantly from the solder and substrate, and excessive IMC layers can lower the reliability of solder joints due to their brittle nature. Moreover, continuous miniaturization of packages and joints has increased the volume fraction of IMCs to a point where smaller joints could be completely composed of IMCs. Further miniaturization of joints may result in statistical grain size effects. One of the most common types of IMCs in microelectronic joints is Cu6Sn5, which is formed in a variety of bonding materials with different compositions of Sn, Cu, and Ag. Due to its large percentage of volume in solder joint; to predict the reliability of micro solder joints, it is necessary to characterize single crystal Cu6Sn5 IMC completely. This study reports the information on grain growth orientation and elastic-plastic properties such as young’s modulus, hardness, yield strength and strain hardening exponent of single grain of Cu6Sn5 in Sn-3.5Ag/Cu solder alloy system. IMCs materials were grown using reflow process using an experiment in which the time and temperature of reflow process was varied. Electron backscatter diffraction (EBSD) analysis was conducted after the reflow to measure the grain size and determine the preferred grain orientation. It was found that the growth orientation is in the orientation of the c-axis. Nanoindentation was carried out in 4 individual grains with different crystallographic orientation along normal to the growth axis to determine the elastic properties of Cu6Sn5 single crystal. Plastic properties were predicted using the nanoindentation results and Dao reverse analysis model. The results indicate that the hardness for Cu6Sn5 grains with different orientation along normal to growth axis is statistically indistinguishable. Lower elastic modulus was observed for a grain with [010] direction parallel to the loading direction. Yield strength of a grain with (001) plane parallel to the loading direction was slightly lower than other grain orientations. Overall, the experimental results obtained were found to be within the range shown in the literature.
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Fahim, Abdullah, Sudan Ahmed, Jeffrey C. Suhling, and Pradeep Lall. "Nanoindentation Measurements of the Mechanical Properties of Individual Phases Within Lead Free Solder Joints Subjected to Isothermal Aging." In ASME 2018 International Technical Conference and Exhibition on Packaging and Integration of Electronic and Photonic Microsystems. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/ipack2018-8408.

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Exposure of lead free solder joints to high temperature isothermal aging conditions leads to microstructure evolution, which mainly includes coarsening of the intermetallic (IMC) phases. In our previous work, it was found that the coarsening of IMCs led to degradation of the overall mechanical properties of the SAC solder composite consisting of β-Sn matrix and IMC particles. However, it is not known whether the isothermal aging changes properties of the individual β-Sn and IMC phases, which could also be affecting to the overall degradation of properties. In this study, the aging induced variations of the mechanical properties of the β-Sn phase, and of Sn-Cu IMC particles in SAC solder joints have been explored using nanoindentation. SAC solder joints extracted from SuperBGA (SBGA) packages were aged for different time intervals (0, 1, 5, 10 days) at T = 125 °C. Nanoindentation test samples were prepared by cross sectioning the solder joints, and then molding them in epoxy and polishing them to prepare the joint surfaces for nanoindentation. Multiple β-Sn grains were identified in joints using optical polarized microscopy and IMCs were also observed. Individual β-Sn grains and IMC particles were then indented at room temperature to measure their mechanical properties (elastic modulus and hardness) and time dependent creep deformations. Properties measured at different aging time were then compared to explore aging induced degradations of the individual phases. The properties of the individual phases did not show significant degradation. Thus, IMC coarsening is the primary reason for the degradation of bulk solder joint properties, and changes of the properties of the individual phases making up the lead free solder material are negligible.
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Bargaoui, Hajer, Nader Mbarek, Olivier Togni, and Mounir Frikha. "IMRR and IMPR routing protocols for inter and intra wireless mesh Communications." In 2015 International Conference on Protocol Engineering (ICPE) and International Conference on New Technologies of Distributed Systems (NTDS). IEEE, 2015. http://dx.doi.org/10.1109/notere.2015.7293490.

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Ma, Hong, Peihao Geng, and Guoliang Qin. "Effect of Alloying Elements of Al Alloy on the Interfacial Microstructure and Fracture Behaviour of Al Alloy/Steel Inertia Friction Welded Joint: A Comparative Study." In ASME 2022 17th International Manufacturing Science and Engineering Conference. American Society of Mechanical Engineers, 2022. http://dx.doi.org/10.1115/msec2022-85196.

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Abstract The present study highlighted the effect of alloying elements in Al alloy on the interfacial microstructure, and the corresponding fracture behaviour of the Al alloy/steel inertia friction welded joint by selectively adopting two types of Al alloys. A strong texture of &lt;111&gt;//radial direction was formed on the Al alloy side in both types of joints, while no obvious changes were identified on the steel side. Different types of intermetallic compounds (IMCs) were formed at the weld interface. In the Al-Mg-Si alloy/steel joint produced at a low heat input, the interfacial microstructure was composed of a nanoscale amorphous layer and partially crystallised layer, while it turned into a fully crystallised Fe2Al5 phase with Si enriched when the heat input was enhanced. In the Al-Cu alloy/steel joint, Cu was enriched at the weld interface, with the possible formation of Fe-Al-Cu based IMCs. Moreover, a two-layered structure of IMC with different compositions of Cu appeared when the joint was prepared at a high heat input. Such distinct interfacial microstructure caused different fracture behaviours of joints. An interfacial reaction layer less than 130 nm thick led to the failure of Al alloy rather than the weld interface which easily happened at a thicker IMC.
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Liu, J., P. Kumar, I. Dutta, C. M. Nagaraj, R. Raj, M. Renavikar, and R. Mahajan. "Effect of Interfacial Layers on the Performance of Cu-In Liquid Phase Sintered Composites as Thermal Interface and Interconnect Materials." In ASME 2011 Pacific Rim Technical Conference and Exhibition on Packaging and Integration of Electronic and Photonic Systems. ASMEDC, 2011. http://dx.doi.org/10.1115/ipack2011-52221.

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In this study, a novel architecture composed of uniformly distributed high melting phase (HMP, e.g. Cu) in a low melting phase (LMP, e.g. In) matrix, which can be produced via liquid phase sintering (LPS), is proposed to produce next generation thermal interface materials (TIMs) and interconnect (IC) materials. The LMP determines the shear compliance of these composites whereas the HMP determines its thermal and electrical conductivities. The volume fraction of In was optimized to produce a Cu-In solder with suitable mechanical, electrical and thermal properties for TIM and IC applications. Since, Cu and In react to form several Cu-In intermetallic compounds (IMCs), which may deteriorate the long-term performance of these solders, interfacial-layers of Au and Al2O3 were applied on Cu to further improve the performance of the Cu-In solders. The effect of interfacial-layers on the reaction between Cu and In, during sintering at 160°C and during aging at 125°C, was studied and its impact on the mechanical, thermal and electrical properties was evaluated. Au interfacial layer (50∼200nm) quickly reacted with In to form AuIn2 IMC, which acted as a tenacious diffusion-barrier and slowed down the reactions between Cu and In. 8-monolayer thick Al2O3 did not react with either Cu or In and inhibited reactions between Cu and In. During short-time sintering, the effect of interfacial layer on the thicknesses of IMCs was insignificant to affect the yield strength of the as-sintered composites. However, IMC layer thickened rapidly in the Cu-In composites without an interfacial-layer, which led to a drastic decrease in the volume fraction of unreacted In leading to an increase in the yield strength of the solder. On the other hand, the interfacial-layers effectively suppressed the growth of IMCs during aging and hence the yield strength of such composites increased at slower rates. Since, the IMCs formed at the interface radically affect the contact resistance, significant differences in the thermal and electrical conductivities were recorded for the solders with different interfacial-layers.
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Ko, K. H., J. O. Choi, and H. Lee. "Abnormal Intermetallic Compound Formation of Cold Sprayed Cu-Sn Coatings." In ITSC2011, edited by B. R. Marple, A. Agarwal, M. M. Hyland, Y. C. Lau, C. J. Li, R. S. Lima, and A. McDonald. DVS Media GmbH, 2011. http://dx.doi.org/10.31399/asm.cp.itsc2011p0320.

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Abstract Cu-Sn composites coatings by cold spray with wide ranges of particle size and shape (round to flake) were investigated regarding their intermetallic compound (IMC) formation. It was found when certain size and shape combination of Cu-Sn composite raw materials were employed, the embedded Cu-Sn IMCs such as Cu6Sn5 and Cu3Sn were observed even in as-sprayed states without additional heat treatments. These results implied that the impact energy of colliding particles of the cold spraying could be enough to activate IMC compounding process. It seems that this can be also true in several composite systems that have relatively low activation energy of IMC compounding. After post annealing, the Cu6Sn5 formed in as-coated state were transformed into the Cu3Sn phase and the residue of unreacted Sn particles were fully changed into the Cu3Sn phase (Cu6Sn5 →Cu3Sn). These conversion processes also depended strongly on the choices of the shape and size combinations of Cu and Sn particles.
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Reports on the topic "IMCR"

1

Gentile, N. Smoothed Emission for IMC. Office of Scientific and Technical Information (OSTI), January 2011. http://dx.doi.org/10.2172/1018761.

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Not Listed. Implementation Plan for the Irradiated Materials Characterization Laboratory (IMCL). Office of Scientific and Technical Information (OSTI), April 2013. http://dx.doi.org/10.2172/1082401.

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Gentile, N. Summer Project on Exponential Convergence for IMC. Office of Scientific and Technical Information (OSTI), May 2016. http://dx.doi.org/10.2172/1255187.

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Stephanie Austad. Conceptual Design Report for the Irradiated Materials Characterization Laboratory (IMCL). Office of Scientific and Technical Information (OSTI), June 2010. http://dx.doi.org/10.2172/984533.

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Campbell, Anne, and Brian Eckhart. Validation of the IMCE RFDA System for Dynamic Elastic Moduli Measurements. Office of Scientific and Technical Information (OSTI), March 2015. http://dx.doi.org/10.2172/1865765.

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Kelley, Timothy M. Adapting an IMC Library to the Roadrunner Architecture. Office of Scientific and Technical Information (OSTI), July 2013. http://dx.doi.org/10.2172/1089475.

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Rickman, Robin, Frank Akstulewicz, and Daniel Carleton. Final Report on TEUSA-NRC Pre-licensing Activities for the IMSR®. Office of Scientific and Technical Information (OSTI), March 2021. http://dx.doi.org/10.2172/1778901.

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Urbatsch, Todd J. FY08 work with IMC radiative transfer in 3D stochastic media. Office of Scientific and Technical Information (OSTI), June 2013. http://dx.doi.org/10.2172/1083835.

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Llanos Cuéllar, Angie Paola. Asma en el paciente ambulatorio. Facultad de Medicina Universidad de Antioquia, April 2024. http://dx.doi.org/10.59473/medudea.pc.2024.73.

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aciente femenina de 35 años con antecedente de asma quien asiste a consulta de control de su patología. Comenta que tiene síntomas como sibilancias y tos casi todos los días de predominio nocturno. Al examen físico se encuentra paciente en buen estado general, signos vitales estables, adecuada saturación de oxígeno al ambiente, se calculó un IMC de 31 kg/m2, en la auscultación pulmonar se encuentran sibilancias espiratorias, sin otros hallazgos adicionales.
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Skinner, Corey Michael. Summer term 2018 work with IMC radiative transport in binary stochastic media. Office of Scientific and Technical Information (OSTI), August 2018. http://dx.doi.org/10.2172/1467246.

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