Academic literature on the topic 'Imidazole-dicarboxylic acid derivatives'

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Journal articles on the topic "Imidazole-dicarboxylic acid derivatives"

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Yakovleva, Ekaterina E., Eugeny R. Bychkov, Maria M. Brusina, Levon B. Piotrovsky, and Petr D. Shabanov. "Pharmacological activity of new imidazole-4,5-dicarboxylic acid derivatives in dopaminergic transmission suppression ttests in mice and rats." Research Results in Pharmacology 6, no. (4) (2020): 51–57. https://doi.org/10.3897/rrpharmacology.6.57883.

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Objective: To study the antiparkinsonian activity of new 1,2-substituted imidazole-4,5-dicarboxylic acids in dopaminergic transmission suppression tests in mice and rats. Materials and methods: On a model of reserpine extrapyramidal disorders, the derivatives of imidazole-dicarboxylic acids (IEM2258, IEM2248, IEM2247) were injected into the lateral brain ventricles of the mice 30 minutes after injecting reserpine at the doses of 0.1–0.5 mmol. Locomotor activity was analyzed in the Open-field test 2 hours later. In the catalepsy model, the studied agents were injected, using a pre-implanted can
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Yasuda, Naohiko. "Synthesis of novel imidazole-4,5-dicarboxylic acid derivatives." Journal of Heterocyclic Chemistry 22, no. 2 (1985): 413–16. http://dx.doi.org/10.1002/jhet.5570220239.

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Yakovleva, Ekaterina E., Eugeny R. Bychkov, Maria M. Brusina, Levon B. Piotrovsky, and Petr D. Shabanov. "Pharmacological activity of new imidazole-4,5-dicarboxylic acid derivatives in dopaminergic transmission suppression ttests in mice and rats." Research Results in Pharmacology 6, no. 4 (2020): 51–57. http://dx.doi.org/10.3897/rrpharmacology.6.57883.

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Abstract:
Objective: To study the antiparkinsonian activity of new 1,2-substituted imidazole-4,5-dicarboxylic acids in dopaminergic transmission suppression tests in mice and rats. Materials and methods: On a model of reserpine extrapyramidal disorders, the derivatives of imidazole-dicarboxylic acids (IEM2258, IEM2248, IEM2247) were injected into the lateral brain ventricles of the mice 30 minutes after injecting reserpine at the doses of 0.1–0.5 mmol. Locomotor activity was analyzed in the Open-field test 2 hours later. In the catalepsy model, the studied agents were injected, using a pre-implanted can
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Khaliullin, Ferkat, Irina Nikitina, Irina Nikitina, et al. "SYNTHESIS AND ANTIDEPRESSANT ACTIVITY OF 2-BROMO-1-(THIETAN-3-YL) IMIDAZOLE-4, 5-DICARBOXYLIC ACID DERIVATIVES." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 8 (2017): 154. http://dx.doi.org/10.22159/ijpps.2017v9i8.17613.

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Objective: Synthesis of the salts and diylidenehydrazidеs of 2-bromo-1-(thietan-3-yl) imidazole-4,5-dicarboxylic acid to evaluate the antidepressant activities.Methods: The structures of the synthesised compounds were confirmed by elemental analysis and 1Н NMR spectral data. The melting points of the compounds were determined on a Stuart SMP30 apparatus. The X-ray diffraction data for compound IIc were obtained at room temperature on a Xcalibur Gemini Еos. The antidepressant activity was investigated in the tail suspension and forced swimming tests. The locomotor activity and anxiety were stud
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Dergachev, V. D., E. E. Yakovleva, M. A. Brusina, E. R. Bychkov, L. B. Piotrovskiy, and P. D. Shabanov. "Antiparkinsonian activity of new N-methyl-D-aspartate receptor ligands in the arecoline hyperkinesis test." Meditsinskiy sovet = Medical Council, no. 12 (September 19, 2021): 406–12. http://dx.doi.org/10.21518/2079-701x-2021-12-406-412.

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Introduction. Parkinson’s disease (PD) is one of the most common neurodegenerative diseases in the population of older patients. Even though long-term combination therapy helps to cope with the main manifestations of PD. It inevitably leads to the appearance of such side effects as drowsiness, hallucinations, dyskinesia, and many others. [12]. Therefore, the search for effective antiparkinsonian drugs devoid of the above-mentioned adverse reactions remains an urgent task of modern neuropharmacology.The explored substances are derivatives of imidazole-4,5-dicarboxylic acid. These compounds belo
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Liu, Yan-Ju, Di Cheng, Ya-Xue Li, Jun-Di Zhang, and Huai-Xia Yang. "A new one-dimensional CdII coordination polymer incorporating 2,2′-(1,2-phenylene)bis(1H-imidazole-4,5-dicarboxylate)." Acta Crystallographica Section C Structural Chemistry 74, no. 10 (2018): 1128–32. http://dx.doi.org/10.1107/s2053229618012603.

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Imidazole-4,5-dicarboxylic acid (H3IDC) and its derivatives are widely used in the preparation of new coordination polymers owing to their versatile bridging coordination modes and potential hydrogen-bonding donors and acceptors. A new one-dimensional coordination polymer, namely catena-poly[[diaquacadmium(II)]-μ3-2,2′-(1,2-phenylene)bis(1H-imidazole-4,5-dicarboxylato)], [Cd(C16H6N4O8)0.5(H2O)2] n or [Cd(H2Phbidc)1/2(H2O)2] n , has been synthesized by the reaction of Cd(OAc)2·2H2O (OAc is acetate) with 2,2′-(1,2-phenylene)bis(1H-imidazole-4,5-dicarboxylic acid) (H6Phbidc) under solvothermal co
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Skoryna, D. Yu, O. Yu Voskoboinik, and S. I. Kovalenko. "Reactions of 1,4-NCCN-, 1,4-NNCN- and 1,5-NCCCN-binucleophiles with dicarboxylic acids cyclic anhydrides as a method of heterocyclic compounds synthesis (a review)." Voprosy Khimii i Khimicheskoi Tekhnologii, no. 3 (June 2023): 29–53. http://dx.doi.org/10.32434/0321-4095-2023-148-3-29-53.

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Critical analysis of published information related to the features of reaction of 1,4-NCCN-, 1,4-NNCN and 1,5-NCCCN-binucleophiles with cyclic anhydrides of dicarboxylic acids has been presented in the review. It has been shown that the reaction of named anhydrides with 1,4-NCCN-binucleophiles leads to the formation of the imidazole fragment that contains carboxyl-containing moiety. It has been shown that benzimidazole derivatives are among the most studied products of reaction between 1,4-NCCN- and cyclic anhydrides of dicarboxylic acids due to the high availability of initial compounds. The
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Iakovleva, E. E., M. A. Brusina, E. R. Bychkov, L. B. Piotrovsky, and P. D. Shabanov. "ANTIPARKINSONIAN ACTIVITY OF NEW LIGANDS OF THE GLUTAMATE NMDA-RECEPTOR COMPLEX - IMIDAZOLE-4,5-DICARBOXYLIC ACID DERIVATIVES." Вестник Смоленской государственной медицинской академии 19, no. 3 (2020): 41–47. http://dx.doi.org/10.37903/vsgma.2020.3.5.

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Baures, Paul W., Adam W. Caldwell, Chris R. Cashman, Marie T. Masse, Ethan B. Van Arnam, and Rebecca R. Conry. "The Influence by Substituents on the Intermolecular Hydrogen-Bonding Interactions in Imidazole-4,5-dicarboxylic Acid Derivatives." Crystal Growth & Design 6, no. 9 (2006): 2047–52. http://dx.doi.org/10.1021/cg060057i.

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Baures, Paul W., Jeremy R. Rush, Alexander V. Wiznycia, John Desper, Brian A. Helfrich, and Alicia M. Beatty. "Intramolecular Hydrogen Bonding and Intermolecular Dimerization in the Crystal Structures of Imidazole-4,5-dicarboxylic Acid Derivatives." Crystal Growth & Design 2, no. 6 (2002): 653–64. http://dx.doi.org/10.1021/cg025549j.

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Conference papers on the topic "Imidazole-dicarboxylic acid derivatives"

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Foksha, Stanislav P., Ekatherina E. Yakovleva, Maria A. Brusina, Evgeniy R. Bychkov, Levon B. Piotrovsky, and Peter D. Shabanov. "Anticonvulsant activity of new antagonists of the glutamate nmda-receptor complex – derivatives of imidazole-4,5-dicarboxylic acids." In II Международная конференция, посвящеенная 100- летию И.А. Држевецкой. СКФУ, 2022. http://dx.doi.org/10.38006/9612-62-6.2022.315.320.

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