Academic literature on the topic 'Imidazoline receptor type I'

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Journal articles on the topic "Imidazoline receptor type I"

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Takamatsu, Isao, Ayano Iwase, Makoto Ozaki, Tomiei Kazama, Keiji Wada, and Masayuki Sekiguchi. "Dexmedetomidine Reduces Long-term Potentiation in Mouse Hippocampus." Anesthesiology 108, no. 1 (2008): 94–102. http://dx.doi.org/10.1097/01.anes.0000296076.04510.e1.

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Background Dexmedetomidine (Precedex; Abbott Laboratories, Abbott Park, IL) is a selective alpha2-adrenergic agonist that also has affinity for imidazoline receptors. In clinical studies, dexmedetomidine has sedative effects and impairs memory, but the action of dexmedetomidine on synaptic plasticity in the brain has yet to be established. In the present study, the authors investigated the effects of dexmedetomidine on two forms of synaptic plasticity-long-term potentiation (LTP) and paired-pulse facilitation-in the CA1 region of mouse hippocampal slices. Methods The authors recorded Schaffer
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Maltsev, A. V., та Y. M. Kokoz. "Non-Central Influences of α2-Adrenergic and Imidazoline Agonist Interactions in Isolated ardiomyocytes Cardiac Cells". Kardiologiia 59, № 4 (2019): 52–63. http://dx.doi.org/10.18087/cardio.2019.4.10241.

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Aim: to investigate the functional interaction of α2-adrenergic and imidazoline receptors recently identified on the sarcolemma of isolated cardiomyocytes for regulation of the intracellular calcium and the production of the signal molecule of nitric oxide (NO).Materials and methods:experiments were performed on isolated left ventricular cardiomyocytes of Wistar rats. Potential-dependent Ca2+-currents were measured from the whole-cell by the patch-clamp method in “perforated-patch” configuration. The intracellular calcium and the production of nitric oxide were estimated from the changes in fl
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Soldatov, Vladislav O., Elena A. Shmykova, Marina A. Pershina, et al. "Imidazoline receptors agonists: possible mechanisms of endothelioprotection." Research Results in Pharmacology 4, no. 2 (2018): 11–19. http://dx.doi.org/10.3897/rrpharmacology.4.27221.

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Imidazoline receptor agonists are one of the groups of contemporary antihypertensive drugs with the pleiotropic cardiovascular effects. In this review, the historical, physiological, pathophysiological aspects concerning imidazoline receptor agonists and possible mechanisms for their participation in endothelioprotection were considered. Illuminated the molecular biology of each subtype of imidazoline receptors and their significance in the pharmacological correction of cardiovascular disease. IR type 1 are localized in the brain nucleus, carrying out the descending tonic control of sympatheti
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Soldatov, Vladislav O., Elena A. Shmykova, Marina A. Pershina, et al. "Imidazoline receptors agonists: possible mechanisms of endothelioprotection." Research Results in Pharmacology 4, no. (2) (2018): 11–18. https://doi.org/10.3897/rrpharmacology.4.27221.

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Imidazoline receptor agonists are one of the groups of contemporary antihypertensive drugs with the pleiotropic cardiovascular effects. In this review, the historical, physiological, pathophysiological aspects concerning imidazoline receptor agonists and possible mechanisms for their participation in endothelioprotection were considered. Illuminated the molecular biology of each subtype of imidazoline receptors and their significance in the pharmacological correction of cardiovascular disease. IR type 1 are localized in the brain nucleus, carrying out the descending tonic control of sympatheti
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Demidova, T. U., A. S. Ametov, and L. V. Smagina. "Moxinidine in the correction of metabolic disturbancis and endothelial dysfunction in patients with diabetes mellitus associated with arterial hypertension." "Arterial’naya Gipertenziya" ("Arterial Hypertension") 10, no. 2 (2004): 104–9. http://dx.doi.org/10.18705/1607-419x-2004-10-2-104-109.

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The paper presents the results of a follow-up and treatment of 30 patients with arterial hypertension (AH) accompanied by the persistent blood pressure elevation that requires continuous antihypertensive therapy and that is associated with type 2 diabetes mellitus. It shows the antihypersensive effect of the imidazoline-receptor agonist moxonidine and its positive action on metabolic parameters and a risk for cardiovascular events in this group of patients.
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Gaponova, N. I., and V. R. Abdrakhmanov. "Theory and practice of selective imidazoline receptor agonist use in Russia." Rational Pharmacotherapy in Cardiology 20, no. 3 (2024): 340–48. http://dx.doi.org/10.20996/1819-6446-2024-3058.

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Activation of the sympathetic nervous system plays an important role in arterial hypertension (AH) development. Antihypertensive drugs of central action contribute to the elimination of sympathetic activation. The selective imidazoline receptor agonist moxonidine has been successfully used in the treatment of patients with hypertension. The review article presents data on the antihypertensive efficacy of moxonidine, the possibility of its use in combination therapy to reduce elevated blood pressure (BP). The effectiveness of moxonidine in overweight patients, metabolic syndrome, diabetes melli
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Zhernakova, Yu V., G. H. Sharipova, and I. E. Chazova. "Patients with arterial hypertension associated with metabolic disorders: characteristics and therapeutic approach." Systemic Hypertension 12, no. 1 (2015): 52–57. http://dx.doi.org/10.26442/sg29094.

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Arterial hypertension (AH) is associated with metabolic disorders in approximately 80% of cases. There is a pandemic of so-called new risk factors, such as insulin resistance and association with systemic type of hyperinsulinemia, abdominal obesity, hyperinsulinemia and a special type of dislipidemy, nowadays. Patients with AH associated with such metabolic disorders are at a higher risk of developing cardiovascular disease and diabetes. However, it is very difficult to achieve the target level of blood pressure in this category of patients. Usually, these patients should be treated using comb
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Kim, Young-Hwan, Ji-Hyun Jeong, Duck-Sun Ahn, and Seungsoo Chung. "Agmatine suppresses peripheral sympathetic tone by inhibiting N-type Ca2+ channel activity via imidazoline I2 receptor activation." Biochemical and Biophysical Research Communications 477, no. 3 (2016): 406–12. http://dx.doi.org/10.1016/j.bbrc.2016.06.086.

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Dahmani, Souhayl, Andrea Paris, Virginie Jannier та ін. "Dexmedetomidine Increases Hippocampal Phosphorylated Extracellular Signal–regulated Protein Kinase 1 and 2 Content by an α2-Adrenoceptor–independent Mechanism". Anesthesiology 108, № 3 (2008): 457–66. http://dx.doi.org/10.1097/aln.0b013e318164ca81.

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Background Dexmedetomidine is a potent and selective alpha2-adrenoceptor (alpha2AR) agonist that exhibits a broad pattern of actions, including sedation, analgesia, and neuroprotection. Recent studies have emphasized the role of phosphorylated extracellular signal-regulated protein kinases (pERK1 and 2) in coupling rapid events such as neurotransmitter release and receptor stimulation long-lasting changes in synaptic plasticity and cell survival. Here, the authors hypothesized that dexmedetomidine increases pERK1 and 2 content and examined the mechanisms involved in this effect. Methods The ef
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Moore, Graham J., Harry Ridgway, Laura Kate Gadanec, Vasso Apostolopoulos, Anthony Zulli, and John M. Matsoukas. "Gating Mechanism for Biased Agonism at Angiotensin II Type 1 Receptors." Molecules 30, no. 11 (2025): 2399. https://doi.org/10.3390/molecules30112399.

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For the interaction of angiotensin II (AngII) with AngII type 1 receptors (AT1R), two potential proton hopping pathways have been identified, each associated with distinct physiological outcomes. The octapeptide AngII (Asp1-Arg2-Val3-Tyr4-Ile5-His6-Pro7-Phe8) appears to form a charge relay system (CRS) in solution in which the C-terminal carboxylate abstracts a proton from the His6 imidazole group, which, in turn, abstracts a proton from the Tyr4 hydroxyl (OH) group, creating a tyrosinate anion. When AngII binds to the AT1R, the CRS can be reconstituted with D281 of the receptor taking up the
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Dissertations / Theses on the topic "Imidazoline receptor type I"

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Sun, Zheng. "IMIDAZOLINE RECEPTORS IN INSULIN SIGNALING AND METABOLIC REGULATION." Case Western Reserve University School of Graduate Studies / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=case1157694260.

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Verdun, Antoine. "Détection et dosage d'une substance endogène de type imidazoline : approche immunologique et hypothèses physio-pathologiques." Université Louis Pasteur (Strasbourg) (1971-2008), 1992. http://www.theses.fr/1992STR1M201.

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Pirnat, Deni. "The importance of the renal sympathetic nerves in the natriuretic response to imidazoline receptor agonists." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/MQ62822.pdf.

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Mueller, Heather. "Depressor and diuretic effects of imidazoline receptor stimulation in the paraventricular nucleus of the hypothalamus." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape9/PQDD_0007/MQ41750.pdf.

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Kawamoto, Shuji. "Bidirectional effects of dexmedetomidine on human platelet functions in vitro." Kyoto University, 2016. http://hdl.handle.net/2433/215391.

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Fischer, Daniel Friedrich. "New frontiers in asymmetric aza-Claisen rearrangements : development of ferrocenyl imidazoline palladacycles /." [S.l.] : [s.n.], 2008. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=18128.

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Dupuy, Laurence. "Etude des effets cellulaires et des mécanismes de transduction associés aux récepteurs des imidazolines de sous type I1." Strasbourg 1, 2004. http://www.theses.fr/2004STR13069.

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Les cellules PC12 expriment le récepteur I1 des imidazolines (RI1) qui est localisé sur la membrane plasmique. Au cours de ce travail, nous avons étudié les voies de transduction associées au RI1 ainsi que son influence sur l'apoptose. Nous avons montré que la stimulation des RI1 provoque une diminution de l'AMPc intracellulaire par l'inhibition de l'adénylate cyclase qui est insensible à la toxine pertussique excluant l'implication d'une protéine G de type Gi/o. Cette voie co-existe avec celle de la phosphatidylcholine phospholipase C dont la stimulation entraîne une augmentation de diacylgly
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Slough, Scott. "The effect of a novel series of imidazoline compounds on glucose homeostasis in the mouse." Thesis, University of Bristol, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.340266.

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Hower, Amy Elizabeth. "Receptor Functions of the Receptor-Type Protein Tyrosine Phosphatase PTPRO." Scholarly Repository, 2008. http://scholarlyrepository.miami.edu/oa_dissertations/303.

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Protein tyrosine phosphorylation regulates many aspects of cell growth and differentiation. Since cellular tyrosine phosphorylation levels are controlled by the antagonizing actions of the protein tyrosine kinases (PTKs) and the protein tyrosine phosphatases (PTPs), these enzymes play a direct role in regulating processes as diverse as oncogenesis and neuronal development. In particular, the transmembrane group of PTPs, known as the receptor-type protein tyrosine phosphatases (RPTPs), has been linked to regulation of axon growth and guidance during development and regeneration. The regulati
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Bolton, L. W. Y. T. "Recombinant TGF-beta type I and type II receptor domains." Thesis, University of Cambridge, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.596753.

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Transforming growth factor-β (TGF-β) is a multifunctional cytokine that signals by binding to two related transmembrane serine/threonine kinases called the type I and type II receptors. The <I>in vitro</I> binding properties of these receptors for the TGF-β1 and TGF-β3 isoforms were investigated by developing expression systems for recombinant extracellular domains (ECDs) of the type I and type II receptors, which also enabled the interaction of the two receptor domains to be examined. 1. A variety of vectors were constructed incorporating the fusion protein glutathione S transferase (GST) and
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Books on the topic "Imidazoline receptor type I"

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A, Hamilton C., Prichard B. N. C, Zwieten P. A. van, and Royal Society of Medicine Services (Great Britain), eds. The I₁-imidazoline receptor agonist moxonidine: A new antihypertensive. Royal Society of Medicine Services Limited, 1994.

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van, Zwieten P. A., ed. The I[subscript 1]-imidazoline receptor agonist moxonidine: A new antihypertensive. 2nd ed. Royal Society of Medicine, 1996.

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J, Reis Donald, Bousquet Pascal, Parini Angelo, and International Symposium on Imidazoline Receptors (2nd : 1994 : New York, N.Y.), eds. The imidazoline receptor: Pharmacology, functions, ligands, and relevance to biology and medicine. New York Academy of Sciences, 1995.

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Ibbotson, Timothy. The imidazoline/guanidine receptor site and its role in potassium channel moulation in vascular smooth muscle. University of Manchester, 1993.

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Playford, Martin P. The role of the type 1 insulin-like growth factor receptor in cancer biology. Oxford Brookes University, 2000.

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Johansson, P. J. Hugo. Herpes simplex virus type 1 induced IgG Fc receptor: Aspects of specificity and function. Univ., 1989.

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1929-, Shigeta Yukio, Kobayashi Masashi Dr, and Olefsky Jerrold M, eds. Recent advances in insulin action and its disorders: Proceedings of the International Symposium on Insulin Action and Its Disorders, Shiga, 16 May 1990. Excerpta Medica, 1991.

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Flavin, Nora. Cloning and characterisation of the bovine activin receptor type II gene (ActRII): Its localisation to chromosome 2 (BTA2) by somatic cell genetic analysis and the genotyping of an associated microsatelltie UCD2. University College Dublin, 1996.

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P.A.Van Zwieten (Editor), C. A. Hamilton (Editor), B.N.C. Prichard (Editor), and S. Julius (Editor), eds. The I1-Imidazoline Receptor Agonist Moxonidine. 2nd ed. Royal Society of Medicine Press Ltd, 1996.

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P.A.Van Zwieten (Editor), C. A. Hamilton (Editor), and B.N.C. Prichard (Editor), eds. The I1-Imidazoline Receptor Agonist Moxonidine. Royal Society of Medicine Press Ltd, 1994.

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Book chapters on the topic "Imidazoline receptor type I"

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Marot, C., N. Baurin, J. Y. Mérour, G. Guillaumet, P. Renard, and L. Morin-Allory. "Imidazoline Receptor Ligands — Molecular Modeling and 3D-QSAR CoMFA." In Molecular Modeling and Prediction of Bioactivity. Springer US, 2000. http://dx.doi.org/10.1007/978-1-4615-4141-7_72.

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Ross, Gordon D. "Receptor Deficiencies: Complement Receptor Type Three." In Hereditary and Acquired Complement Deficiencies in Animals and Man. KARGER, 1987. http://dx.doi.org/10.1159/000318560.

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Bisogno, Tiziana, and Mauro Maccarrone. "Type-1 Cannabinoid Receptor." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_101565.

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Piehler, Jacob. "Type I Interferon Receptor." In Encyclopedia of Biophysics. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-16712-6_795.

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Sheikh, Søren Paludan. "Angiotensin Type 2 Receptor." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_451.

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Cascio, Caterina, Patrizia Guarneri, Hua Li, et al. "Peripheral-Type Benzodiazepine Receptor." In Neurosteroids. Humana Press, 1999. http://dx.doi.org/10.1007/978-1-59259-693-5_5.

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Bisogno, Tiziana, and Mauro Maccarrone. "Type-1 Cannabinoid Receptor." In Encyclopedia of Signaling Molecules. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4614-6438-9_101565-1.

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Biswas-Fiss, Esther E., Stephanie Affet, Malissa Ha, et al. "A-Type Endothelin Receptor." In Encyclopedia of Signaling Molecules. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_100096.

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van Roy, Frans, Volker Nimmrich, Anton Bespalov, et al. "Cholecystokinin Type A Receptor." In Encyclopedia of Signaling Molecules. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_100264.

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Miki, Toru, Randa Hilal-Dandan, Laurence L. Brunton, et al. "Endothelin Receptor Type A." In Encyclopedia of Signaling Molecules. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_100391.

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Conference papers on the topic "Imidazoline receptor type I"

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Ding, Yuan, Bruce Brown, David Young, Srdjan Nesic, and Marc Singer. "Effect of Temperature on Adsorption Behavior and Corrosion Inhibition Performance of Imidazoline-Type Inhibitor." In CORROSION 2017. NACE International, 2017. https://doi.org/10.5006/c2017-09350.

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Abstract In the present study, the effect of temperature on the adsorption/desorption kinetics and thermodynamics of diethylenetriamine talloil fatty acid imidazoline (DETA/TOFA imidazoline) is studied on a gold coated crystal using a quartz crystal microbalance (QCM) in a CO2 saturated 1wt% NaCl aqueous solution. Concurrently, the corrosion inhibition performance of imidazoline on API 5L X65 steel was also investigated at different temperatures using linear polarization resistance (LPR). QCM results show that the adsorption of imidazoline-type inhibitor generally follows the Langmuir adsorpti
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Mizukami, Hirotaka, Ayano Yasui, Tatsuya Sei, et al. "Effect of Inhibitor Component on Inhibitor Efficiency - Inhibitor Types and Intensifier." In CONFERENCE 2022. AMPP, 2022. https://doi.org/10.5006/c2022-17791.

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Abstract Imidazoline, which is known as one of the active ingredients of corrosion inhibitors, is used in a lot of oil and gas facilities in order to mitigate corrosion problems. However, it is easily hydrolyzed to amide, which leads to the change of inhibitor efficiency. Therefore, the inhibitor efficiency of imidazoline-type and amide-type inhibitors was evaluated by several tests such as electrochemical measurements, weight loss test and quartz crystal microbalance measurement. Furthermore, the effect of one intensifier for corrosion inhibitor was also evaluated by the same tests. As a resu
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Gough, M. A., W. H. Durnie, E. K. Auty, and Bill Hedges. "Characterization, Isolation and Performance Characteristics of Imidazolines." In CORROSION 2002. NACE International, 2002. https://doi.org/10.5006/c2002-02301.

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Abstract Imidazolines have been used in the area of corrosion inhibition since at least the mid 1940's when it was shown that long chain organic compounds with polar functional groups had corrosion inhibition properties when applied to oil-field environments. Many fundamental studies involving imidazoline-type compounds have been conducted and reported but although many acknowledge that conventional imidazoline contains multiple species, i.e., imidazoline, amide precursor etc., none have endeavoured to separate/isolate the various components. Therefore, the extent to which each of the componen
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Ding, Yuan, Bruce Brown, David Young, and Marc Singer. "Effectiveness of an Imidazoline-type Inhibitor against CO2 Corrosion of Mild Steel at Elevated Temperatures (120°C-150°C)." In CORROSION 2018. NACE International, 2018. https://doi.org/10.5006/c2018-11622.

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Abstract Production of oil and gas from increasingly aggressive geologic environments requires the development of appropriate corrosion mitigation strategies, including the selection of corrosion inhibitors with adequate performance characteristics. In this study, the inhibition performance of a diethylenetriamine tall oil fatty acid imidazoline-type inhibitor (DETA/TOFA imidazoline) against CO2 corrosion of an API 5L X65 carbon steel was studied at two temperatures, 120°C and 150°C. The corrosion measurements were performed in a CO2 saturated 1 wt.% NaCl electrolyte, via electrochemical measu
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Nalini, D., and R. Rajalakshmi. "Inhibition of Mild Steel Corrosion in the Presence of p-Nitrophenyl-2-Imidazoline." In CORROSION 2013. NACE International, 2013. https://doi.org/10.5006/c2013-02189.

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Abstract p-nitrophenyl-2-imidazoline (PNP2I) was synthesized in the laboratory and characterized by Fourier Transform Infrared Spectroscopy (FTIR) spectra and evaluated as a corrosion inhibitor for mild steel in 1M Hydrochloric acid and 0.5M Sulphuric acid by weight loss method and electrochemical studies. Results obtained revealed that PNP2I was a very good inhibitor and behaved better in 0.5M H2SO4 than in 1M HCl. Potentiodynamic polarization curves showed that PNP2I is a mixed type inhibitor. The ability of the studied inhibitor to inhibit the corrosion of mild steel was due to the presence
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Matherly, Ron M., Jian Jiao, David J. Blumer, and Jeffery S. Ryman. "Determination of Imidazoline and Amido-Amine Type Corrosion Inhibitors in Both Crude Oil and Produced Brine from Oilfield Production." In CORROSION 1995. NACE International, 1995. https://doi.org/10.5006/c1995-95543.

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Abstract The classical method for the determination of corrosion inhibitors in oilfield brines is the dye transfer method. Within this method are many variations which the analyst may use to determine the amount of corrosion inhibitor in either water or crude oil. These methods, however, suffer from many interferences which result in both false positive and negatives for corrosion inhibitor content. These methods essentially detect all amines as corrosion inhibitors. Improved high pressure liquid chromatography (HPLC) methods have been developed for the analysis of quaternary salt type corrosi
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Martin, R. L., B. A. Alink, J. A. McMahon, and R. Weare. "Further Advances in the Development of Environmentally Acceptable Corrosion Inhibitors." In CORROSION 1999. NACE International, 1999. https://doi.org/10.5006/c1999-99098.

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Abstract The environmental fate of specialty chemicals used in petroleum recovery processes has received increased attention in recent years. Our laboratory has contributed to early advances in this field. This paper outlines further systematic studies. The influences of alkoxylation, starting amine type, and acid chain length on imidazoline properties were studied in addition to the properties of blends. The properties considered were corrosion inhibition, biodegradability, marine organism toxicity, octanol/water partitioning, and vapor pressure. A cross section of field test and application
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Hassani, Shokrollah, Jin Huang, Ana Camila Victor, Bruce Brown, and Marc Singer. "Inhibited Under-Deposit CO2 Corrosion: Small Particle Silica Sand and Eicosane Paraffin Deposits." In CORROSION 2017. NACE International, 2017. https://doi.org/10.5006/c2017-09564.

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Abstract Chemical inhibition in the presence of silica sand deposit has been reported as a cause of severe localized corrosion attack in CO2-saturated brine environments. This paper suggests a new mechanism for explaining physics behind the localized corrosion attack based on experimental evidences. The effect of sand size and deposit type on localized corrosion attack in the presence of imidazoline type inhibitor is also experimentally investigated in CO2-saturated brine solution. Smaller silica sand particles (diameter less than 44 micron) are found to cause less localized corrosion attack i
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Choi, Yoon-Seok, Shokrollah Hassani, Thanh Nam Vu, et al. "Corrosion Inhibition of Carbon Steel in Supercritical CO2/H2S Environments." In CORROSION 2018. NACE International, 2018. https://doi.org/10.5006/c2018-11193.

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Abstract The effect of small amounts of H2S on the corrosion behavior and corrosion protection of carbon steel was investigated in high pressure CO2 environments. The experiments were carried out in a 7.5L autoclave with two combinations of CO2 partial pressure and temperature (12 MPa/80°C and 8 MPa/25°C) with different H2S concentrations (0, 100 and 200 ppm). The corrosion behavior of specimens was evaluated using electrochemical measurements and surface analytical techniques. It was found that the addition of small amounts of H2S reduced the corrosion rate of carbon steel in high pressure CO
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Turnbull, A., D. Coleman, A. J. Griffiths, P. E. Francis, and L. Orkney. "Effectiveness of Corrosion Inhibitors in Retarding Propagation of Localised Corrosion." In CORROSION 2002. NACE International, 2002. https://doi.org/10.5006/c2002-02274.

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Abstract In many service applications excursions in solution chemistry, temporary loss of inhibitor, or transient increases in temperature may give rise to localised corrosion in an otherwise inhibited system. It is important to demonstrate that inhibition will be effective in retarding propagation of localised corrosion when normal conditions, appropriate to prevention of general corrosion, are restored. To test this requirement, the use of a ‘pencil’ type of artificial pit has been investigated using simple simulations of a cooling water and of an oil production formation water. The results
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Reports on the topic "Imidazoline receptor type I"

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Reiss, Michael. Type I Receptor Kinase Inhibitors - A Novel Treatment for Breast Cancer. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada408030.

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Fagan, Dedra. Type-I Insulin-Like Growth Factor Receptor (IGF1R)-Estrogen Receptor (ER) Crosstalk Contributes to Antiestrogen Therapy Resistance in Breast Cancer Cells. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada575846.

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Reise, Michael. TGF-beta Type I Receptor Kinase Inhibitors - A Novel Treatment for Breast Cancer. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada416442.

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Rausch, Matthew. Enhancement of Dendritic Cell-Based Immunotherapy Using a Small Molecule TGF-beta Receptor Type I Kinase Inhibitor. Defense Technical Information Center, 2008. http://dx.doi.org/10.21236/ada487435.

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Plymate, Stephen R. Therapy of Prostate Cancer Using a Human Antibody Targeting the Type 1 Insulin-Like Growth Factor Receptor (IGF-IR). Defense Technical Information Center, 2009. http://dx.doi.org/10.21236/ada524529.

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Thomas, Tania, S. Shappell, S. Kasper, R. A. Serra, and H. L. Moses. The Development and Characterization of a Transgenic Mouse Model Over-Expressing a Truncated TGF(Beta) Type II Receptor in the Prostate. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada390670.

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Deo, Salil, David McAllister, Naveed Sattar, and Jill Pell. The time-varying cardiovascular benefits of glucagon like peptide-1 agonist (GLP-RA)therapy in patients with type 2 diabetes mellitus: A meta-analysis of multinational randomized trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.7.0097.

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Abstract:
Review question / Objective: P - patients with type 2 diabetes melllitus already receiving routine medical therapy; I - patients receiving glucagon like peptide 1 receptor agonist (GLP1 receptor agonist) therapy (semaglutide, dulaglutide, liraglutide, exenatide, lixisenatide, efpeglenatide, abiglutide); C - patients receiving standard therapy for diabetes mellitus but not receiving GLP1 agonist therapy; O - composite end point as per invididual trial, cardiovascular mortality, all-cause mortality, myocardial infarction, stoke. Condition being studied: Type 2 diabetes mellitus. Study designs to
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Zhuo, Chuanjun, Hongjun Tian, Lina Wang, Xiangyang Gao, Li Ding, and Ming Liu. Comparative safety of glucagon like peptide‑1 receptor agonists in patients with type 2 diabetes: a network meta-analysis of cardiovascular outcome trials. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2020. http://dx.doi.org/10.37766/inplasy2020.8.0122.

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Zhao, Fang, Haoshu Wang, Shenguang Li, Hezhang Yun, and Wenbo Su. The Effects of GLP-1 Receptor Agonists on Metabolic Inflammatory Markers in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2025. https://doi.org/10.37766/inplasy2025.4.0020.

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Sisler, Edward C., Raphael Goren, and Akiva Apelbaum. Controlling Ethylene Responses in Horticultural Crops at the Receptor Level. United States Department of Agriculture, 2001. http://dx.doi.org/10.32747/2001.7580668.bard.

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Ethylene is a plant hormone that controls many plant responses, such as growth, senescence, ripening, abscission and seed germination. Recently, 1-methy- cyclopropene (1-MCP), was shown to bind to ethylene receptor for a certain period of time and prevent ethylene action. The objectives of this research were to synthesize analogues of 1-MCP and test their potency to block the ethylene receptor and inhibit ethylene action. During the course of this project, procedures for synthesis and shipment of the cyclopropene compounds were developed as well assay procedures for each compound were worked o
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