Relevant bibliographies by topics / Imidazopyridine

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  2. Dissertations / Theses
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Academic literature on the topic 'Imidazopyridine'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 July 2025

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Journal articles on the topic "Imidazopyridine"

1

Tran, Christine, and Abdallah Hamze. "Recent Developments in the Photochemical Synthesis of Functionalized Imidazopyridines." Molecules 27, no. 11 (2022): 3461. http://dx.doi.org/10.3390/molecules27113461.

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Imidazopyridines constitute one of the most important scaffolds in medicinal chemistry, as their skeleton could be found in a myriad of biologically active molecules. Although numerous strategies were elaborated for imidazopyridine preparation in the 2010s, novel eco-compatible synthetic approaches have emerged, conscious of climate change concerns. In this framework, photochemical methods have been promoted to conceive this heterocyclic motif over the last decade. This review covers the recently published works on synthesizing highly functionalized imidazopyridines by light induction.
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Volpi, Giorgio, Enzo Laurenti, and Roberto Rabezzana. "Imidazopyridine Family: Versatile and Promising Heterocyclic Skeletons for Different Applications." Molecules 29, no. 11 (2024): 2668. http://dx.doi.org/10.3390/molecules29112668.

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In recent years, there has been increasing attention focused on various products belonging to the imidazopyridine family; this class of heterocyclic compounds shows unique chemical structure, versatile optical properties, and diverse biological attributes. The broad family of imidazopyridines encompasses different heterocycles, each with its own specific properties and distinct characteristics, making all of them promising for various application fields. In general, this useful category of aromatic heterocycles holds significant promise across various research domains, spanning from material s
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Hamdi, Abdeljalil, Yahya El Hammoudani, M’hamed Ahari, et al. "Various Synthesis of Imidazo[1,2-a]pyridines Derivatives and Therapeutic Significance: A Review." BIO Web of Conferences 109 (2024): 01005. http://dx.doi.org/10.1051/bioconf/202410901005.

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The synthesis of bicyclic heterocycles, notably nitrogen-containing imidazopyridines, holds immense appeal due to their structural diversity and pivotal role in biological systems. These compounds are ubiquitously found in nature and are prized for their significance in both chemical and biological contexts. Imidazopyridine derivatives, among nitrogen heterocycles, serve as fundamental structures in various applications spanning pharmaceuticals to food additives. Consequently, their synthesis and modification represent a focal point in both natural and synthetic organic chemistry. This review
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Sonawane, Ravindra S., Kiran D. Patil, and Avinash V. Patil. "Design, Synthesis and Pharmacological Evaluation of Novel Imidazopyridine Analogues as Proton Pump Antagonist." Asian Journal of Chemistry 32, no. 4 (2020): 776–82. http://dx.doi.org/10.14233/ajchem.2020.22433.

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A series of novel imidazopyridine derivatives as proton pump inhibitors was designed with compounds of CID data base and explored considering AZD0865 as standard. Many compounds were identified and docked in proton pump ATPase pocket (PDB ID: 4ux2). Molecular docking studies revealed that many compounds showed good proton pump ATPase inhibitory activity. The docking poses revealed the interaction of ligands with amino acid. The standard drug AZD0865 had docking score of -7.112302 and displayed interactions with Asn138 and Asp137. A series of novel imidazopyridine derivatives as proton pump inh
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Sonawane, R. S., Mrunal Shirsat, S. R. Patil, J. C. Hundiwale, and A. V. P. atil. "Design and Synthesis of Novel Imidazopyridine Analogues and Evaluation as H+/K+-ATPase Antagonist." Asian Journal of Chemistry 32, no. 11 (2020): 2685–92. http://dx.doi.org/10.14233/ajchem.2020.22697.

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CID data base were explored considering AZD0865 as standard and docked in proton pump ATPase pocket (PDB ID: 4ux2) to find out novel imidazopyridine derivatives as proton pump inhibitors. A number of compounds showed good proton pump ATPase inhibitory activity as per the molecular docking study as compared to standard compound AZD0865. The compound AZD0865showed a docking score of -7.11 and revealed the interactions with amino acids Asn 138 and Asp 137. A series of novel imidazopyridine derivatives as proton pump inhibitors were docked, synthesized and characterized by IR, NMR, CHN and MS spec
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Hamdi, Abdeljalil, Chaimae Elyoussfi, M’hamed Ahari, et al. "Synthesis and Medicinal Applications of Imidazopyridine and Imidazothiazole Derivatives: A Review." E3S Web of Conferences 527 (2024): 01014. http://dx.doi.org/10.1051/e3sconf/202452701014.

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Imidazopyridine and its derivatives are essential heterocycles widely utilized in medicinal chemistry, natural products, and synthetic chemicals. The unique structural characteristics of the imidazopyridine ring facilitate their interaction with various enzymes and receptors through weak interactions, leading to a wide range of biological and pharmacological effects. Many imidazole derivatives are extensively used in clinical practice to treat various diseases, highlighting their significant potential for further research. This review provides a comprehensive synthesis of current research on i
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Peterson, Emily A., Alessandro A. Boezio, Paul S. Andrews, et al. "Discovery and optimization of potent and selective imidazopyridine and imidazopyridazine mTOR inhibitors." Bioorganic & Medicinal Chemistry Letters 22, no. 15 (2012): 4967–74. http://dx.doi.org/10.1016/j.bmcl.2012.06.033.

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Obaidi, Oday A., Zeyad Kadhim Oleiwi, Nidhal Hatif Hammood, and Hussein Ali A. l-Bahrani. "SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF NEW IMIDAZOPYRIDINE DERIVATIVES BASED ON 2,3-DIAMINOPYRIDINE." ACTA CHEMICA IASI 32, no. 2 (2024): 237–48. https://doi.org/10.47743/achi-2024-2-0013.

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The present research work focuses on the synthesis and evaluation of antibacterial activity of newly developed imidazopyridine analogues arising from 2,3-aminopyridine substructure. Three new imidazopyridine derivatives have been synthesized from the reaction of 2,3-aminopyridine with ibuprofen, naproxen and etodolac employing HCl as both the solvent and the catalyst. The resulting compounds were identified by using (FTIR) and (¹H-NMR). The antibacterial activity of these newly synthesized compounds was carried out against a series of bacteria: Escherichia coli, Klebsiella pneumoniae, Staphylo
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Carreño, Alexander, Manuel Gacitúa, Juan A. Fuentes, et al. "Theoretical and experimental characterization of a novel pyridine benzimidazole: suitability for fluorescence staining in cells and antimicrobial properties." New Journal of Chemistry 40, no. 3 (2016): 2362–75. http://dx.doi.org/10.1039/c5nj02772a.

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Mali, Suraj N., Amit Anand, Magdi E. A. Zaki, et al. "Theoretical and Anti-Klebsiella pneumoniae Evaluations of Substituted 2,7-dimethylimidazo[1,2-a]pyridine-3-carboxamide and Imidazopyridine Hydrazide Derivatives." Molecules 28, no. 6 (2023): 2801. http://dx.doi.org/10.3390/molecules28062801.

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A series of multistep synthesis protocols was adopted to synthesize substituted imidazopyridines (IMPs) (SM-IMP-01 to SM-IMP-13, and DA-01-05). All substituted IMPs were then characterized using standard spectroscopic techniques such as 1H-NMR, 13C-NMR, elemental analyses, and mass spectrometry. Our both in vitro qualitative and quantitative results for antibacterial analysis, against Klebsiella pneumoniae ATCC 4352 and Bacillus subtilis ATCC 6051 suggested that all compounds essentially exhibited activity against selected strains of bacteria. Our DFT analyses suggested that the compounds of t
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Dissertations / Theses on the topic "Imidazopyridine"

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Björk, Malin. "Synthesis of sulfur and seleniumn heterocycles, including derivatives of imidazopyridine and benzimidazole /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-597-6/.

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Chezal, Jean-Michel. "Reaction d'heteroannelation en serie azaalcaloique : acces aux synthons imidazoaziniques d'interet pharmacologique." Clermont-Ferrand 1, 1997. http://www.theses.fr/1997CLF1PP02.

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Raihane, Mohamed. "Reactions d'annelation en serie imidazo(1,2-a)pyridine : acces aux systemes pyridoimidazo(iso)quinoleiniques et imidazopyridodiazepiniques isosteres de tibo." Clermont-Ferrand 1, 1996. http://www.theses.fr/1996CLF1PP01.

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MADADI, MESSAOUD NACER. "Recherche en pharmacochimie heterocyclique antiparasitaire : pharmacomodulation de derives thiopheniques et reactions de transfert monoelectronique en serie imadazo (1,2-a) pyridine et en serie imadazo (2,1-b) thiazole." Aix-Marseille 2, 1991. http://www.theses.fr/1991AIX22956.

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Tang, Yue. "Catalyse asymétrique en présence de complexes d'or(I) - Un nouvel arsenal pour la construction d'architectures moléculaires." Thesis, Paris Sciences et Lettres (ComUE), 2019. http://www.theses.fr/2019PSLEC038.

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Au cours des dernières années, la catalyse de l'or a pris une importance considérable en synthèse organique, du fait de l’efficacité de nombreux systèmes dans des réactions tandem à économie d’atomes et d’étapes. Malgré des progrès remarquables, les variantes énantiosélectives n’ont pas prospéré aussi rapidement et elles restent encore un challenge à la fois en terme de généralité et d’efficacité. Ce projet vise à répondre à certaines barrières technologiques et à contribuer à la recherche fondamentale dans le domaine des cycloisomérisations asymétriques et réactions domino impliquant à la foi
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Arama, Patomo Dominique. "Conception et synthèse de nouveaux inhibiteurs de la kallicréine 7." Thesis, Montpellier, 2015. http://www.theses.fr/2015MONT3503/document.

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Les kallikréines (KLKs) tissulaires humaines sont des protéases à sérine « (chymo)trypsine-like » impliquées dans divers processus physiologiques. Parmi les 15 isoformes connues dans la littérature, la kallikréine 7 (KLK7) est particulièrement impliquée dans les processus de desquamation. La dérégulation de cette enzyme est associée à diverses atteintes dermatologiques, telles que le psoriasis ou la maladie de Netherton. Il est également admis que cette enzyme participe à l'invasion tumorale et à la progression du cancer de la prostate, des ovaires et du pancréas. L'utilisation d'inhibiteurs d
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Jouanisson, Anne. "Etude en série azaindolique : synthèse et approche pharmacologique." Clermont-Ferrand 1, 1994. http://www.theses.fr/1994CLF1PP03.

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Wazeerud-Din, Idris. "Synthetic Approaches towards Novel Isoform Selective PI3K Inhibitors and Their Biological Activities against Prostate Cancer Cells." DigitalCommons@Robert W. Woodruff Library, Atlanta University Center, 2018. http://digitalcommons.auctr.edu/cauetds/143.

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The development of novel imidazopyridines, which includes both tetrahydroimidazo[1,5-a]pyridine (rIMP) and imidazo[1,5-a]pyridine (IMP) was investigated using conventional and microwave induced procedures that afforded compounds at high yield of 88-96%. rIMP was synthesized using a two-step procedure that involved the microwave synthesis of IMP, then the reduction of the pyridine moiety of the fused imidazopyridine rings using 10% Pd/C and hydrazine monohydrate. The microwave synthesis of imidazopyridines involved the one pot reaction of 2-benzoylpyridine, substituted benzaldehyde and ammonium
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Ahmed, Mustafe. "Synthesis of imidazopyridazine analogs aiming to improve antibacterial Gram-negative activity." Thesis, Uppsala universitet, Institutionen för läkemedelskemi, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-449572.

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Silva, Daniel Gedder. "Planejamento, síntese e avaliação de inibidores da enzima cruzaína e de agentes tripanossomicidas derivados de imidazopiridina." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/75/75133/tde-16012018-091612/.

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No capítulo 1, a modelagem HQSAR, a docagem e os estudos de ROCS foram construídos utilizando uma série de 57 inibidores de cruzaína. O melhor modelo HQSAR (q2 = 0,70, r2 = 0,95, r2test = 0,62, q2rand. = 0,09 and r2rand. = 0,26) foi utilizado para predizer a potência de 121 compostos extraídos da literatura (conjunto de dados V1), resultando em um valor de r2 satisfatório de 0,65 para essa validação externa. Uma validação externa adicional foi empregada utilizando uma série de 1223 compostos extraído dos bancos de dados ChEMBL e CDD (conjunto de dados V3); nessa validação externa o valor de AU
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Books on the topic "Imidazopyridine"

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Stilnox, Imidazopyridine Symposium (1st 1990 Strasbourg France). Stilnox 1st Imidazopyridine Symposium: 10th Congress of the European Sleep Research Society (augmented proceedings) = 10ème Congrès de la Société européenne de recherche sur le sommeil (comptes rendus avec supplément). Adis International, 1991.

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P, Sauvanet J., Langer S. Z, Morselli Paolo Lucio, and Laboratoires d'études et de recherches Synthélabo., eds. Imidazopyridines in sleep disorders: A novel experimental and therapeutic approach. Raven Press, 1988.

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G, Bartholini, ed. Imidazopyridines in anxiety disorders: A novel experimental and therapeutic approach. Raven Press, 1993.

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Sauvanet, J. P., and S. Z. Langer. Imidazopyridines in Sleep Disorders: A Novel Experimental and Therapeutic Approach (L.E.R.S. Monograph Series, Vol 6). Raven Pr, 1987.

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Imidazopyridines in Anxiety Disorders: A Novel Experimental and Therapeutic Approach (L E R S Monograph Series). Raven Pr, 1993.

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Book chapters on the topic "Imidazopyridine"

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Daoudi, Walid, Omar Dagdag, Salma Lamghafri, Rajesh Haldhar, and Abdelmalik El Aatiaoui. "Pyridine-, Imidazopyridine-, and Pyrimidine-based Corrosion Inhibitors." In Handbook of Heterocyclic Corrosion Inhibitors. CRC Press, 2023. http://dx.doi.org/10.1201/9781003377016-13.

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Powers, Frances M., Kimberly A. Palmiter, and R. John Solaro. "E-1020, a water soluble imidazopyridine, has direct effects on Ca2+-dependent force and ATP hydrolysis of canine and bovine cardiac myofilaments." In Biochemical Mechanisms in Heart Function. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-1279-6_4.

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Sanghavi, Kartik, Bonny Y. Patel, Vijay Khedkar, and Khushal M. Kapadiya. "Imidazo-Pyridines." In Advances in Chemical and Materials Engineering. IGI Global, 2025. https://doi.org/10.4018/979-8-3693-7267-8.ch011.

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The structural resemblance between the fused imidazopyridine heterocyclic ring system (a purine system) has prompted biological investigations to assess their potential therapeutic significance. They are known to play a crucial role in numerous disease conditions. In recent years, new preparative methods for the synthesis of imidazopyridines using various catalysts or non-catalytic systems have been described. In the present chapter, we summarise the recent approaches adopted for the synthesis of functionalized imidazo-pyridines over the last two decades along with their clinical advancement a
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Yutilov, Yuriy M. "Imidazopyridines: 1- and 3-Deazapurines." In Advances in Heterocyclic Chemistry. Elsevier, 2005. http://dx.doi.org/10.1016/s0065-2725(05)89004-x.

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Ghosh, Sumit, Madhusudan Mondal, Sudip Laru, and Alakananda Hajra. "Photoinduced Synthesis of Imidazopyridines and Imidazothiazoles." In Topics in Heterocyclic Chemistry. Springer Berlin Heidelberg, 2025. https://doi.org/10.1007/7081_2025_83.

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Conference papers on the topic "Imidazopyridine"

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Deore, Nitin R., Tushar Janardan Pawar, Yadav K. Nagare, and Sachin V. Patil. "Electrochemical Synthesis of Imidazopyridine and Benzylidene Malononitrile." In International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2022. http://dx.doi.org/10.3390/ecsoc-26-13567.

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Petrarolo, Giovanni, Edoardo Gelardi, Giorgia Colombo, et al. "2,6-Diphenyl-imidazopyridine derivatives as novel prototypes of anticancer agents targeting aldehyde dehydrogenases." In 6th International Electronic Conference on Medicinal Chemistry. MDPI, 2020. http://dx.doi.org/10.3390/ecmc2020-07431.

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Cai, Xiong, Hai-Xiao Zhai, Jing Wang, et al. "Abstract 3249: Design and synthesis of imidazopyridine derivatives as novel HSP90 inhibitors for the treatment of cancer." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-3249.

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Petrocchi, Alessia, Naphtali J. Reyna, Faika Mseeh, et al. "Abstract LB-071: Discovery of an imidazopyridine series of potent human IDO1 inhibitors with robust target engagement in a preclinical tumor model." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-lb-071.

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Yang, Bin, Jamal C. Saeh, Bo Peng, et al. "Abstract 3910: Lead optimization of a series of 5-aminopyrazol-imidazopyridine compounds as potent anaplastic lymphoma kinase inhibitors active against clinically relevant ALK mutations." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-3910.

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Mendonça, Cleber R., André Pelosi, Leando Cocca, et al. "Nonlinear absorption investigation in imidazopyridines derivates." In Organic Photonic Materials and Devices XXIV, edited by Ileana Rau, Okihiro Sugihara, and William M. Shensky. SPIE, 2022. http://dx.doi.org/10.1117/12.2608889.

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