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Dissertations / Theses on the topic 'Immature and mature dendritic cells'

Author: Grafiati
Published: 18 May 2024

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1

Patel, Ekta. "IgM antibodies enhance the phagocytosis of apoptotic cells by immature dendritic cells." Diss., [La Jolla] : University of California, San Diego, 2009. http://wwwlib.umi.com/cr/ucsd/fullcit?p1462525.

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Thesis (M.S.)--University of California, San Diego, 2009.<br>Title from first page of PDF file (viewed May 8, 2009). Available via ProQuest Digital Dissertations. Includes bibliographical references (p. 45-47).
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2

Blair, Derek. "Signalling mechanisms regulating proliferation and apoptosis in immature and mature B cells." Thesis, University of Glasgow, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.400789.

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3

Geng, Shuo. "Discovery of a New Dendritic Cell Subset Derived from Immature Granulocytes." University of Toledo Health Science Campus / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=mco1294155495.

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4

Ismail, Ida Shazrina Binti. "Identification of peptides capable of targeting immature dendritic cells using phage display." Thesis, Imperial College London, 2012. http://hdl.handle.net/10044/1/10484.

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The ability of dendritic cells (DC) to be either tolerogenic or immunogenic offers many opportunities to manipulate DC function and genetically modify DC to promote allograft acceptance. However, the greatest challenge in DC gene therapy is the difficulty of achieving successful transfection. At present, DC-targeting gene delivery strategies are hindered by the lack of DC-specific target molecules. Therefore, the essential aim of this study is to isolate and identify peptides capable of targeting immature DC (iDC), in particular those that internalise well as they are likely to be more effecti
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5

Khanolkar, Rahul Chaitanya. "Molecular analysis of ABIN1 expression and immunosuppressive function in immature myeloid cells." Thesis, University of Aberdeen, 2013. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=202767.

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The leukocyte immunoglobulin like receptors (LILRs) are a group of receptors with immunomodulatory effects. Group 1 LILRs comprise of LILRB1, among others, and bind to class 1 MHC molecules and transmits inhibitory signals. Studies have shown that LILRB1 ligation during the monocyte differentiation process into dendritic cells (DCs) results in the generation of a population of cells that are tolerogenic. Here we hypothesize that this tolerogenic nature of the resultant cells is due to the high expression of nuclear factor kappa – light chain enhancer of activated B cells (NF-κB) inhibitor – A2
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6

Solanes, Paola. "IP3 Receptor 3 controls migration persistency and environment patrolling by immature dendritic cells." Thesis, Paris 5, 2013. http://www.theses.fr/2013PA05T020/document.

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Le succès de la réponse immunitaire repose en grande partie sur la capacité des leucocytes à se déplacer et à accomplir leur fonction au sein de structures anatomiques précises. Le fait qu’il puisse exister des mécanismes intrinsèques de coordination entre ces fonctions spécifiques et la migration de ces cellules n’a jamais été étudié auparavant. Nos travaux mettent en évidence, pour la première fois, l’existence d’un couplage entre la migration et la macropinocytose dans les cellules dendritiques qui explorent leur environnement en internalisant une grande quantité de matériel extra-cellulair
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7

Ito, Takeshi. "Bone marrow endothelial cells induce immature and mature B cell egress in response to erythropoietin." Kyoto University, 2018. http://hdl.handle.net/2433/232127.

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8

Gutzeit, Cindy. "Interference of Varicella-Zoster Virus (VZV) with the CD1 antigen presenting system on immature dendritic cells." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2009. http://dx.doi.org/10.18452/16059.

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Das human pathogene Varicella-Zoster Virus (VZV) gehört zur Familie der Herpesviren und ist weltweit verbreitet. Die Primärinfektion verursacht Varicellen, welche durch einen bläschenartigen Hautausschlag charakterisiert ist. Im Anschluss daran etabliert VZV eine lebenslange Latenz und verursacht nach Reaktivierung Herpes Zoster. Seit 2004 ist der Lebendimpfstoff aus attenuierten Virionen des VZV-Stammes V-Oka in Deutschland empfohlen. Im Gegensatz zur Infektion mit zirkulierenden virulenten VZV Stämmen tritt nach Verimpfung des Vakzin-Stammes V-Oka kein Exanthem auf. Die Haut ist der Hauptrep
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9

Yu, Hyun Jae. "HIV Traffics Through a Specialized, Surface-accessible Intracellular Compartment During Trans-infection of T Cells by Mature Dendritic Cells." Case Western Reserve University School of Graduate Studies / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=case1266871870.

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10

Kather, Angela. "Pro- and antiapoptotic events in Herpes simplex virus type 1 (HSV-1) infection of immature dendritic cells." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2012. http://dx.doi.org/10.18452/16464.

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Herpes simplex virus Typ 1 (HSV-1) ist ein humanpathogenes Virus der Familie Herpesviridae. Für eine erfolgreiche Virusreplikation besitzt HSV-1 mehrere Gene, die in den meisten infizierten Zelltypen Apoptose verhindern. Im Gegensatz dazu führt die HSV-1 Infektion eines zentralen Zelltyps des Immunsystems, den unreifen dendritischen Zellen (iDCs), zu Apoptose. Dies könnte ein Aspekt der HSV-1 Immunevasion sein. Bisher waren die Ursachen der Apoptose von HSV-1 infizierten iDCs unzureichend aufgeklärt. Es wurde jedoch gezeigt, dass das antiapoptotische zelluläre Protein c-FLIP in HSV-1 infiziert
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11

Riedel, Jan-Hendrik [Verfasser], and Ulf [Akademischer Betreuer] Panzer. "Immature renal dendritic cells recruit regulatory CXCR6+ invariant Natural Killer T cells to attenuate crescentic GN / Jan-Hendrik Riedel. Betreuer: Ulf Panzer." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2013. http://d-nb.info/1036729265/34.

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12

Buck, Matthew Philip. "Development and optimization of a workflow to enable mass spectrometry-based quantitative membrane proteomics of mature and tolerogenic dendritic cells." Thesis, University of Newcastle upon Tyne, 2014. http://hdl.handle.net/10443/3296.

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Tolerogenic dendritic cells are monocyte-derived dendritic cells (DC) cultured such that they adopt an immunoregulatory phenotype. In vitro, these cells are able to induce and maintain T cell tolerance through deviation of naive T cells to an anti-inflammatory phenotype and induction of anergy in memory T cells. Equivalent cells suppress established arthritis in murine models and tolerogenic DC are presently the subject of a phase I safety and efficacy trial at Newcastle University as part of the AutoDeCRA study. However, in spite of these promising data, we are yet to rigorously explore the b
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13

Gutzeit, Cindy [Verfasser], Carmen [Gutachter] Scheibenbogen, Detlev H. [Gutachter] Krüger, and Andreas [Gutachter] Sauerbrei. "Interference of Varicella-Zoster Virus (VZV) with the CD1 antigen presenting system on immature dendritic cells / Cindy Gutzeit ; Gutachter: Carmen Scheibenbogen, Detlev H. Krüger, Andreas Sauerbrei." Berlin : Humboldt-Universität zu Berlin, 2009. http://d-nb.info/1208074458/34.

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14

Kather, Angela [Verfasser], Detlev H. [Akademischer Betreuer] Krüger, Birgit [Akademischer Betreuer] Sawitzki, and Sebastian [Akademischer Betreuer] Voigt. "Pro- and antiapoptotic events in Herpes simplex virus type 1 (HSV-1) infection of immature dendritic cells / Angela Kather. Gutachter: Detlev H. Krüger ; Birgit Sawitzki ; Sebastian Voigt." Berlin : Humboldt Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2012. http://d-nb.info/1020229926/34.

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15

Perroud, Junior Mauricio Wesley 1971. "Avaliação de viabilidade, tolerância e segurança da vacina com células dendríticas autológas maduras em pacientes com carcinoma de pulmão não pequenas células avançado = Assessment of feasibility, safety and tolerance of mature autologous dendritic cells vaccine in patients with advanced non-small cell lung carcinoma." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/310256.

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Orientador: Lair Zambon<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-21T10:28:19Z (GMT). No. of bitstreams: 1 PerroudJunior_MauricioWesley_D.pdf: 9913138 bytes, checksum: 5dd1ec64b004b6d50e2392e6383c9c98 (MD5) Previous issue date: 2012<br>Resumo: Os resultados terapêuticos globais do carcinoma de pulmão não pequenas células em estádio avançado são bem limitados. A imunoterapia com células dendríticas foi desenvolvida como uma nova estratégia para o tratamento de câncer de pulmão. O objetivo deste estudo foi aval
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16

Li, Chien-Chih, and 李建志. "The effects of autophagy on H5N1 infection in immature dendritic cells." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/01478383652366256199.

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碩士<br>國立陽明大學<br>醫學生物技術暨檢驗學系<br>103<br>H5N1 is one of avian influenza viruses with high mortality rate. From 2003, H5N1 has accounted for more than 440 people death. Previous studies revealed that H5N1-induced cytokine dysregulation may be a main reason of high mortality. Besides, our past study also demonstrated that dendritic cells capture H5N1 to infect other cells. H5N1 infected cells produced considerable amounts of cytokines and even caused severe cell death. Nevertheless, there is no clear answer of how H5N1 causes cytokine dysregulation. Autophagy is a highly conserved behavior in the e
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17

Gutzeit, Cindy [Verfasser]. "Interference of Varicella-Zoster virus (VZV) with the CD1 antigen presenting system on immature dendritic cells / von Cindy Gutzeit." 2009. http://d-nb.info/1002215315/34.

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18

You, Yi-Te, and 尤儀德. "Generation of Mature Dendritic Cells from Murine Splenocytes Cultured with Tumor Cells Transduced with GM-CSF and Interleukin-4 Genes: Implications for tumor Immunotherapy." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/64465342271662030870.

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碩士<br>國立成功大學<br>微生物暨免疫學研究所<br>88<br>Tumor vaccines derived from genetically modified tumor cells or from tumor antigen-pulsed dendritic cells (DCs) show promise in cancer immunotherapy. DCs can be generated from bone marrow-derived cells and splenocytes in the presence of GM-CSF and IL-4. DCs would mature into functional tumor antigen-presenting cells under the exposure to tumor cells or tumor extracts. In this study, the strategies based on DCs combined with genetically engineered tumor cells expressing GM-CSF and IL-4 were exploited to test the feasibility of generation of mature DCs in vitr
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19

Tiurbe, George Christian. "Characterization of immature rat bone marrow-derived dendritic cells : Evaluation of their phenotype and immunomodulatory properties in vitro and after organ transplantation." Doctoral thesis, 2006. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-21429.

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Solid organ transplantation is an established therapeutic approach in modern medicine to extend and to improve the life of patients in the final stages of organ failure. Transplantation between genetically non-identical individuals leads to the activation of the transplant recipient's immune system. This alloimmune response is a consequence of the recognition of foreign MHC molecules by alloreactive host T cells. To prevent their activation and the subsequently induced activation of further cell subsets (e.g. B cells, cytotoxic T cells, macrophages)immunosuppressive drugs are absolutely necess
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20

Tiurbe, George Christian [Verfasser]. "Charakterisierung unreifer dendritischer Zellen aus dem Knochenmark der Ratte : Untersuchungen zum Phänotyp und zur Immunmodulation in vitro und nach Organtransplantation = Characterization of immature rat bone marrow-derived dendritic cells / vorgelegt von George Christian Tiurbe." 2007. http://d-nb.info/982940254/34.

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