Academic literature on the topic 'Immunantw'

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Journal articles on the topic "Immunantw"

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Butenas, Saulius, Behnaz Parhami-Seren, Matthew T. Gissel, Edward D. Gomperts, and Kenneth G. Mann. "Quantitative Evaluation of Factor VIII in Factor VIII Products." Blood 104, no. 11 (2004): 4012. http://dx.doi.org/10.1182/blood.v104.11.4012.4012.

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Abstract Several factor VIII products, recombinant and natural, have been used for hemophilia A treatment worldwide. Typically, two activity-based assays (factor Xase and aPTT) are used for the assessment of factor VIII concentration in these products. Frequently, the results are dependent upon the assay and its modifications in different laboratories. In this study, we evaluated five pharmacologic factor VIII products (three lots of each) in three activity-based assays and in two immunoassays for the concentration and activity of factor VIII protein. Two factor VIII products were plasma-deriv
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Ver Elst, Kristien, Huub van Vliet, Mies Kappers-Klunne, and Frank Leebeek. "In vitro studies, pharmacokinetic studies and clinical use of a high purity double virus inactivated FVIII/VWF concentrate (Immunate) in the treatment of von Willebrand disease." Thrombosis and Haemostasis 92, no. 07 (2004): 67–74. http://dx.doi.org/10.1160/th04-02-0107.

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SummaryPatients with type 2 and 3 von Willebrand disease (VWD) are treated with factor VIII/VWF concentrate in case of bleeding or surgery. Immunate® (Baxter, Vienna, Austria) is a double virus inactivated FVIII/VWF concentrate and is registered in several countries for patients with VWD with reduced FVIII levels.We performed an in vitro, a pharmacokinetic and a clinical study to evaluate Immunate in VWD. In vitro studies showed a significant variation in VWF levels in 9 different batches. The median (range) values (in IU/mL) were 1.10 (0.98-1.30) for FVIII:C, 1.34 (0.95-1.61) for VWF:Ag, 0.60
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Altynbekov, O. M., and A. V. Andreeva. "INFLUENCE OF IMMUNOSTIMULATORS ON MORPHOLOGICAL AND IMMUNOBIOCHEMICAL PARAMETERS OF BLOOD OF PREGNANT COWS AND NEWBORN CALVES." RUSSIAN ELECTRONIC SCIENTIFIC JOURNAL 36, no. 2 (2020): 215–23. http://dx.doi.org/10.31563/2308-9644-2020-36-2-215-223.

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The article reflects the results of changes in the biochemical and morphological parameters of blood, as well as the content of total protein and its fractions under the influence of immunostimulators in black-and-white cows and calves obtained from them. The aim of the study was to study the effect of the immunostimulators “Recombinant Bovine Interferon” and “Immunate” on the morphological and immunobiochemical blood parameters of pregnant cows and newborn calves. Studies were conducted on 45 pregnant cows divided into three groups based on the principle of analogues, and, subsequently, on 45
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Nemes, L., T. Lissitchkov, G. Dobaczewski, et al. "Pharmacokinetics, Efficacy and Safety of IMMUNATE® Solvent/Detergent (IMMUNATE® S/D) in Previously Treated Patients with Severe Hemophilia A: Results of a Prospective, Multicenter, Open-Label Phase III Study." Acta Haematologica 119, no. 2 (2008): 89–97. http://dx.doi.org/10.1159/000118628.

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NEMES, L., T. LISSITCHKOV, A. KLUKOWSKA, et al. "Evaluation of pharmacokinetics, efficacy and safety of Immunate�solvent detergent in previously treated patients with severe haemophilia A." Haemophilia 13, no. 1 (2007): 9–11. http://dx.doi.org/10.1111/j.1365-2516.2006.01412.x.

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Falter, Tanja, Mirjeta Qorraj, Sarah Steinemann, Thomas Vigh, and Inge Scharrer. "Evaluation of Clotting Factor Concentrates for Treatment of Thrombotic Thrombocytopenic Purpura." Blood 116, no. 21 (2010): 3678. http://dx.doi.org/10.1182/blood.v116.21.3678.3678.

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Abstract Abstract 3678 Introduction: Thrombotic thrombocytopenic purpura (TTP) is characterized by microthrombi, hemolytic anemia as well as thrombocytopenia. These symptoms are caused by a decreased activity of the protease ADAMTS13 which cleaves the von Willebrand Factor (VWF), due to mutation of the ADAMTS13-gene or autoantibodies. At the moment, the only available immediate therapy is plasmapheresis with Fresh Frozen Plasma (FFP) which may induce side effects. Therefore an alternative therapy might be the treatment with clotting factor concentrates. Methods: 40 plasma samples were tested,
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Auerswald, G., B. Eberspacher, B. Eifrid, et al. "A high-purity double virus inactivated FVIII/vWF concentrate (Immunate) in the successful treatment of patients with von Willebrand disease." Haemophilia 8, no. 6 (2002): 836. http://dx.doi.org/10.1046/j.1365-2516.2002.d01-2_3.x.

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Altynbekov, O. M., and A. V. Andreeva. "THE EFFECT OF «RECOMBINANT BOVINE INTERFERON» AND «IMMUNATE» ON THE ACCUMULATION OF SPECIFIC ANTIBODIES TO ASSOCIATIVE INFECTION AGENTS IN THE BLOOD OF CALVES." VESTNIK OF THE BASHKIR STATE AGRARIAN UNIVERSITY 50, no. 2 (2019): 45–50. http://dx.doi.org/10.31563/1684-7628-2019-50-2-45-50.

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Аbramchik, L. M., I. N. Domanskaya, V. N. Makarov, et al. "Influence of “Immunact-GK” and “Ecosil” preparations on the photosynthetic apparatus and oxidative status of tomato plants in conditions of small volume hydroponics." Proceedings of the National Academy of Sciences of Belarus, Biological Series 65, no. 3 (2020): 283–91. http://dx.doi.org/10.29235/1029-8940-2020-65-3-283-291.

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Auerswald, Günter, Bruno Eberspächer, Werner Engl, et al. "Successful Treatment of Patients with von Willebrand Disease using a High-Purity Double-Virus Inactivated Factor VIII/von Willebrand Factor Concentrate (Immunate®)." Seminars in Thrombosis and Hemostasis 28, no. 2 (2002): 203–14. http://dx.doi.org/10.1055/s-2002-27822.

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Dissertations / Theses on the topic "Immunantw"

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Heink, Sylvia. "Die proteasomale Homöostase." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2005. http://dx.doi.org/10.18452/15308.

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Das Proteasom spielt eine zentrale Rolle beim Proteinabbau und der Antigen-Generierung für die adaptive Immunantwort. Vertebraten exprimieren zwei Typen des proteolytischen 20S-Kernkomplexes: das konstitutive c20S (mit den aktiven Untereinheiten beta 1, 2, 5) und das Immunoproteasom i20S (mit den Immunountereinheiten LMP2, MECL-1, LMP7). Die i20S-Expression wird durch Interferon_gamma (IFNg) induziert, was die Antigen-Präsentation auf MHC Klasse I und die Immunantwort gegen infizierte bzw. maligne entartete Zellen durch cytotoxische T-Zellen steigert. Proteasomen werden über komplexe, bisher
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Deicke, Tobias. "Untersuchungen zum Magendilatations-Magendrehungssyndrom des Hundes in Beziehung zur Magenflora unter besonderer Berücksichtigung toxinogener Clostridien." Doctoral thesis, Universitätsbibliothek Leipzig, 2008. http://nbn-resolving.de/urn:nbn:de:bsz:15-20081120-100428-4.

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Das MMS stellt eine lebensbedrohliche Erkrankung großwüchsiger Hunde dar. Die ansteigenden Inzidenzzahlen der letzten Jahre, die ungeklärte Ätiologie sowie die hohe Mortalitätsrate rechtfertigen weitere Untersuchungen zu diesem Krankheitskomplex. Daher wurden in der vorliegenden Arbeit Mageninhalte (30 Tiere mit MMS / 13 Kontrolltiere) und Blutproben (102 Tiere mit MMS / 116 Kontrolltiere) mikrobiologisch, biochemisch (kurz-kettige Fettsäuren, Amylase, Lipase, Laktat, pH) und immunologisch (BotNt, CRP, Gesamt-immunglobuline, IgA-, IgG- und IgM-Spiegel ausgewählter mikrobieller Antigene) unters
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Book chapters on the topic "Immunantw"

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Kobelt, R., W. Engl, and B. Eberspächer. "Hemmkörper-Hämophilie A: Induktion einer Immuntoleranz mit IMMUNATE STIM plus." In 29. Hämophilie-Symposion. Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-59633-9_40.

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Turecek, P. L., W. Schönhofer, T. R. Kreil, et al. "IMMUNATE S/D — A new Factor VIII — von-Willebrand Factor Complex Concentrate." In 33rd Hemophilia Symposium. Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-642-18260-0_17.

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Auerswald, G., B. Eberspächer, W. Kreuz, et al. "Successful Treatment of Patients with von Willebrand Disease Using a High-Purity Double Virus Inactivated FVIII/vWF Concentrate (IMMUNATE)." In 30th Hemophilia Symposium Hamburg 1999. Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-642-18240-2_19.

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Hofmann, K., and J. U. Strassburger. "Herniotomie nach Rehbein beiderseits unter kontinuierlicher Infusion mit Immunate STIM plus bei einem 41/2jährigen Patienten mit von-Willebrand-Syndrom Typ 2 A, Subtyp II E." In 29. Hämophilie-Symposion. Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-59633-9_36.

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Kinch, Michael. "Sea Monsters, Immunauts, and Death Panels." In Prescription for Change. University of North Carolina Press, 2016. http://dx.doi.org/10.5149/northcarolina/9781469630625.003.0009.

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We return to the rise of biotechnology, revealing the risks and rewards arising from recombinant DNA technologies as evidenced by the formation and ultimate dissolution of the first biotechnology company. Cetus succeeded in creating innovative breakthrough but its business side lost to competition, hastenign its demise. We then transition to witness the rise and fall of Seattle-based Immunex, which again introduced revolutionary medicines but whose inability to manufacture enough product fated it to be acquired by Amgen. In another venture, a founder of Immunex started a second company, which developed a product that was a technological hit but failed due to a structural means by which new medicines are prescribed. Such challenges were observed and addressed by other startups, such as Amgen and Genzyme, which executed successful scientific and business strategies. The rise of Genzyme in particular reflected an opportunity afforded by the passage of the Orphan Drug Act, which granted special incentives to products targeting low-incidence diseases.
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