Academic literature on the topic 'Immune-modulatory effects'

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Journal articles on the topic "Immune-modulatory effects"

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Stevens, Dennis L. "Immune modulatory effects of antibiotics." Current Opinion in Infectious Diseases 9, no. 3 (June 1996): 165–70. http://dx.doi.org/10.1097/00001432-199606000-00007.

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Zeiser, Robert. "Immune modulatory effects of statins." Immunology 154, no. 1 (February 20, 2018): 69–75. http://dx.doi.org/10.1111/imm.12902.

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Zweegman, S., J. J. W. M. Janssen, and H. M. Lokhorst. "Immune-modulatory effects of bortezomib in GVHD." Leukemia & Lymphoma 48, no. 5 (January 2007): 853–54. http://dx.doi.org/10.1080/10428190701297394.

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KLAESSON, S., O. RINGDEN, L. MARKLING, M. REMBERGER, and I. LUNDKVIST. "Immune Modulatory Effects of Immunoglobulins on Cell-Mediated Immune Responses In Vitro." Scandinavian Journal of Immunology 38, no. 5 (November 1993): 477–84. http://dx.doi.org/10.1111/j.1365-3083.1993.tb02591.x.

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Pellom, Samuel Troy, Duafalia Fred Dudimah, Menaka Chanu Thounaojam, Thomas Joseph Sayers, and Anil Shanker. "Modulatory effects of bortezomib on host immune cell functions." Immunotherapy 7, no. 9 (September 2015): 1011–22. http://dx.doi.org/10.2217/imt.15.66.

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Siddiqui, Maheen, Judhell S. Manansala, Hana A. Abdulrahman, Gheyath K. Nasrallah, Maria K. Smatti, Nadin Younes, Asmaa A. Althani, and Hadi M. Yassine. "Immune Modulatory Effects of Vitamin D on Viral Infections." Nutrients 12, no. 9 (September 21, 2020): 2879. http://dx.doi.org/10.3390/nu12092879.

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Viral infections have been a cause of mortality for several centuries and continue to endanger the lives of many, specifically of the younger population. Vitamin D has long been recognized as a crucial element to the skeletal system in the human body. Recent evidence has indicated that vitamin D also plays an essential role in the immune response against viral infections and suggested that vitamin D deficiency increases susceptibility to viral infections as well as the risk of recurrent infections. For instance, low serum vitamin D levels were linked to increased occurrence of high burdens viral diseases such as hepatitis, influenza, Covid-19, and AIDS. As immune cells in infected patients are responsive to the ameliorative effects of vitamin D, the beneficial effects of supplementing vitamin D-deficient individuals with an infectious disease may extend beyond the impact on bone and calcium homeostasis. Even though numerous studies have highlighted the effect of vitamin D on the immune cells, vitamin D’s antiviral mechanism has not been fully established. This paper reviews the recent mechanisms by which vitamin D regulates the immune system, both innate and adaptive systems, and reflects on the link between serum vitamin D levels and viral infections.
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Bahadar, Haji, Mohammad Abdollahi, Faheem Maqbool, Maryam Baeeri, and Kamal Niaz. "Mechanistic Overview of Immune Modulatory Effects of Environmental Toxicants." Inflammation & Allergy-Drug Targets 13, no. 6 (June 15, 2015): 382–86. http://dx.doi.org/10.2174/1871528114666150529103003.

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FUCHSLUGER, T. "Immune modulatory effects of gene therapy to corneal grafts." Acta Ophthalmologica 90 (August 6, 2012): 0. http://dx.doi.org/10.1111/j.1755-3768.2012.2745.x.

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Sinha, M., M. Griffith, C. Betts, G. Choe, S. Sivagnanam, A. Cheung, W. Tamaki, et al. "Immune modulatory effects of ibrutinib in pancreatic ductal adenocarcinoma." Annals of Oncology 30 (July 2019): iv40. http://dx.doi.org/10.1093/annonc/mdz155.145.

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De Pablo, Manuel A., and Gerardo Álvarez De Cienfuegos. "Modulatory effects of dietary lipids on immune system functions." Immunology and Cell Biology 78, no. 1 (February 2000): 31–39. http://dx.doi.org/10.1046/j.1440-1711.2000.00875.x.

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Dissertations / Theses on the topic "Immune-modulatory effects"

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Vos, Arjan Paul. "Preclinical studies on the immune-modulatory effects of dietary oligosaccharides." [Maastricht] : Maastricht : Maastricht University ; University Library, Universiteit Maastricht [host], 2008. http://arno.unimaas.nl/show.cgi?fid=10681.

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Bundscherer, Lena Christina [Verfasser]. "Immune-modulatory effects of non-thermal plasma / Lena Christina Bundscherer." Greifswald : Universitätsbibliothek Greifswald, 2014. http://d-nb.info/1050266897/34.

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Klaesson, Sven. "Immune modulatory effects of intravenous immunoglobulin in vitro and after allogeneic bone marrow transplantation /." Stockholm, 1997. http://diss.kib.ki.se/1997/91-628-2636-0.

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Helal, Racha [Verfasser]. "Biopharmaceutical investigations of the effects of immune-modulatory plant extracts and phytochemicals on lysozyme expression in human cells / Racha Helal." Berlin : Freie Universität Berlin, 2011. http://d-nb.info/1025490010/34.

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Mohan, C. V. "Modulatory effects of cadmium and copper on the susceptibility and immune response of common carp, Cyprinus carpio (L) to selected pathogens." Thesis, University of Stirling, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.280056.

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Fernandes, Antonio Celestino. "Investigation of the immune-modulatory effects of erythromycin." Thesis, 1986. https://hdl.handle.net/10539/25754.

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A Dissertation submitted to the Faculty of Medicine, University of the Witwatersrand, Johannesburg, for the Degree of Master of Science (MED). JOHANNESBURG, 1986
The Literature Review covers the immunosuppressive and immunopotentiating properties of antibiotics on the immune system and the effects these could have on the resolution of an infection. The possible pathogenic mechanisms of C. albicans are also reviewed in this section. The experimental section shows that pre-treatment of mice with erythromycin increases the mean survival time following intraperitoneal inoculation of C. albicans. It was shown that erythromycin enhanced lymphocyte transformation and PMNL migration in both in-vivo and in-vitro situations. These enhanced immunological components probably caused improved survival times in the aforementioned animal experiments. To investigate the effects of oral administration of erythromycin on in-vivo PMNL migration in adult volunteers a new quantitative test which could only be applied to humans was developed and is described in detail. Using this method preliminary data were obtained which show that erythromycin increases PMNL migration in-vivo.
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Shih, Song-Shan, and 施松杉. "Immune modulatory effects by acupmoxa on cecal ligation and puncture induced septic rats." Thesis, 1999. http://ndltd.ncl.edu.tw/handle/05059083129673110795.

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碩士
國立陽明大學
傳統醫藥學研究所
87
Abdominal infection raises severe septic cascades, and usually results in multiple organs failure (MOF). The balance of pro- and anti-inflammatory cytokines is related to disease severity and host survival. Prevention and early treatment remain the management strategy for such abdominal sepsis. Acupuncture and moxibustion (acupmoxa) is well known to control infectious diseases. However, the exact mechanism remains unclear. Our aim is to test the hypothesis that somatic stimulation by electro-acupuncture (EA) or by moxibustion-like local heat (LH) is the better effective management to improve the survival rates and clinical outcomes of septic animals. Abdominal sepsis was induced on female Spraque-Dawley rats (200-300g) by using cecal ligation and puncture (CLP) method. Somatic stimulation by EA or moxibustion-like LH on right upper quadrant acupoints Qimen (Liv-14) and Riyue (GB-24) were used twice a day at 9:00 a.m. and 5:00 p.m. for 5 days after the onset of CLP-induced sepsis. Animals were randomly allocated into four groups. They were sham (negative control), CLP-EA, CLP-LH, and CLP-alone (positive control) group. At definite time points of 0, 8, 24, 72, and 120 hours following CLP, parameters of infection such as hematocrit, SGPT, white blood cells count, serum nitrite level, serum interleukin-1b level and interleukin-10 level, as well as hepatic iNOS gene expression were measured. Finally, the survival rates of the stratification groups were analyzed by Kaplan & Meier''s method. The cumulative survival rates at 24 hr and 48 hr in sham group (n=13), CLP-EA group (n=23), CLP-LH group (n=28) and CLP-alone group (n=25) were 100.0% and 100.0%, 69.6% and 60.9%, 25.0% and 14.3%%, and 48.0% and 44.0%, respectively (p<0.001). The CLP-EA group also showed a better outcome, interms of parameters of infection, on the control of CLP-induced sepsis. The hepatic iNOS gene expression was down-regulated by CLP-EA or CLP-LH manipulation. We conclude that early electro-acupuncture (EA) can improve the clinical outcomes on CLP-induced abdominal sepsis, and provides an easily applicable alternative for those patients with abdominal sepsis.
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Kriegeskorte, Anja Kerstin [Verfasser]. "Analysis of immune-modulatory effects of NKG2D ligands on T cells / Anja Kerstin Kriegeskorte." 2007. http://d-nb.info/985919639/34.

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Chen, Yi-Lien, and 陳逸璉. "The immuno-modulatory effects of polysaccharides from Antrodia camphorata on immune effector cells and OVA-induced asthmatic mice." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/50814301482063018934.

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碩士
臺北醫學大學
醫學科學研究所
96
Antrodia camphorata (syn. Taiwanofungus camphorata) is a special medicinal mushroom in Taiwan. Previous studies showed that polysaccharides isolated from Antrodia camphorata (AC-PS) had the anti-inflammation and anti-tumor abilities. However, the modulatory effects of AC-PS in antigen presenting cell (APC) and T cell are unclear. In this study, we first examined the immune-modulatory effects of the purified polysaccharides isolated from Antrodia camphorata (GF-2) on dendritic cells (DCs) and T cells. Our data showed that GF-2 enhanced the production of IL-10 and IL-12 from DCs challenged with LPS. GF-2 also increased the expression of CD80 and CD86 on DCs. However, GF-2 combined with LPS reduced the expression of MHC classⅡ. In addition, GF-2-treated DCs markedly drive T cells to develop into IL-10-secreting T cells. These results indicated that GF-2 promoted the production of IL-10 to modulate immune response in vitro. In vivo, mice were immunized with OVA plus GF-2 to investigate the modulatory effects of GF-2. Our data showed that GF-2 significantly inhibited the production of OVA-specfic IgE and IgG1. GF-2 not only decreased the release of IL-5 but also increased the production of IL-10 and IFN-γ in splenocytes. Considering these results, we suggested that GF-2 could attenuate IL-5 by enhancing the production of IL-10 and IFN-γ. Furthermore, we evaluated the preventive effect of GF-2 in asthmatic animal model. The results showed that GF-2 decreased airway hyperresponsiveness (AHR), eosinophilia and Th2 cytokines secretion. In conclusion, we suggested that GF-2 could modulate the response of asthma and we hope GF-2 might be used as novel therapeutic reagent for asthma treatment.
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Lee, Wan-Yun, and 李宛芸. "The modulatory effects of zerumbone on the immune effector cells and airway inflammation in a murine model of asthma." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/02295449951983433042.

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Books on the topic "Immune-modulatory effects"

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Zughaier, Susu M., Erik Lubberts, and Abdulbari Bener, eds. Immune-Modulatory Effects of Vitamin D. Frontiers Media SA, 2020. http://dx.doi.org/10.3389/978-2-88966-174-9.

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Book chapters on the topic "Immune-modulatory effects"

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Frey, Benjamin, Michael Rückert, and Udo S. Gaipl. "Immune Modulatory Effects of Radiotherapy." In Radiation Oncology, 1–12. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-52619-5_106-1.

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Liu, Ko-Jiunn, Men-Luh Yen, Li-Tzu Wang, and B. Linju Yen. "The modulatory effects of mesenchymal stromal cells on the innate immune system." In The Biology and Therapeutic Application of Mesenchymal Cells, 481–89. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2016. http://dx.doi.org/10.1002/9781118907474.ch33.

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Yen, B. Linju, Ko-Jiunn Liu, Men-Luh Yen, and Huey-Kang Sytwu. "The modulatory effects of mesenchymal stromal cells on the adaptive immune system." In The Biology and Therapeutic Application of Mesenchymal Cells, 490–95. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2016. http://dx.doi.org/10.1002/9781118907474.ch34.

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Kolodziej, Herbert, Oliver Kayser, Klaus Peter Latté, and Albrecht F. Kiderlen. "Enhancement of Antimicrobial Activity of Tannins and Related Compounds by Immune Modulatory Effects." In Plant Polyphenols 2, 575–94. Boston, MA: Springer US, 1999. http://dx.doi.org/10.1007/978-1-4615-4139-4_32.

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Huang, Lixing, Rongchao He, Youyu Zhang, and Qingpi Yan. "The Role of the Aryl Hydrocarbon Receptor (AhR) in the Immune Response against Microbial Infections." In Antimicrobial Immune Response [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96526.

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Aryl hydrocarbon receptor (AhR), an important nuclear receptor, regulates the cellular response to environmental stressors. It is well known for its critical functions in toxicology, but is currently considered an essential regulator of diseases, with specific modulatory effects on immune, antimicrobial and inflammatory responses. The present chapter discusses AhR’s function and mechanism in the immune response against microbial infections.
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Gupta, Anil. "Functional Foods in Hypertension." In Advances in Environmental Engineering and Green Technologies, 376–96. IGI Global, 2017. http://dx.doi.org/10.4018/978-1-5225-0591-4.ch017.

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Functional foods contain bioactive compounds which are endowed with remarkable biologically significant properties. These compounds have corrective and preventive potential for diseases affecting cardiovascular system, endocrine system, nervous system, alimentary canal by virtue of their capability to influence bio-macromolecules in the cells. Clinical evidence augments the anti-oxidant, anti-atherogenic, anti-ageing, cardio-protective and immune system modulatory role of the functional foods. However, additional research is necessitated to uncover concerns regarding optimal dose, duration, pharmaco-therapeutics and adverse effects of active compounds in relation to the public health.
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Arlt, Wiebke. "Dehydroepiandrosterone and ageing." In Oxford Textbook of Endocrinology and Diabetes, 1511–19. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199235292.003.0134.

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Dehydroepiandrosterone (DHEA) is the crucial precursor of human sex steroid synthesis and thus mediates the majority of its effects indirectly, following downstream conversion to sex steroids and other steroids of potentially distinct activity. No specific receptor for DHEA or its sulfate ester DHEAS has been identified yet. However, there is evidence of specific binding sites for DHEA on immune and vascular cells and for direct interaction with cell signaling cascades, which may facilitate direct effects of DHEA. DHEA is mainly secreted by the adrenal zona reticularis and, together with cortisol and aldosterone, represents one of three major steroids produced by the adrenal glands. However, in contrast to cortisol and aldosterone, circulating concentrations of DHEA and its sulfate ester DHEAS show a physiological decline with ageing. Seminal studies in patients with adrenal insufficiency, who suffer from pronounced DHEA deficiency, have illustrated the physiological significance of DHEA (1–4) (Chaper 5.9) and its role as an efficient vehicle for female androgen replacement. Importantly, studies in systemic lupus erythematosus have started to define a role for DHEA as an immune modulatory drug. By contrast, the few randomized controlled trials on DHEA supplementation in healthy elderly adults have yielded largely disappointing results. However, irrespective of the very scarce evidence, DHEA is perceived by the lay public as a ‘fountain of youth’ hormone, based merely on the observation of declining serum levels with ongoing ageing. This has led to widespread, uncontrolled use, further facilitated by its inappropriate classification as a ‘food supplement’ by the US Food and Drug Administration. Two issues are important to consider when assessing the scientific literature on the potential clinical effects of DHEA. Firstly, the capability of the adrenal gland to produce DHEA is only observed in some but not all mammals, and thus represents a recent evolutionary development. Most importantly, the adrenal glands of rodents do not express CYP17 and therefore cannot synthesize DHEA. Therefore, the potential for transferring results of rodent experiments to the human situation is limited. To date, many reports on DHEA effects, in particular with regard to protection against cancer, heart disease, diabetes, and obesity (5) are based on the administration of grossly supraphysiologic DHEA doses in rodent models. The second problem in the scientific DHEA literature is the multitude of studies based on associations rather than mechanistic insights, which often results in oversimplification of perceived causalities. This is exemplified by the multitude of studies demonstrating various effects of DHEA on longevity, which then is used by many to claim a general antiageing effect. In this chapter, a closer look at the available current evidence with regard to the role of DHEA in ageing humans is provided.
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Conference papers on the topic "Immune-modulatory effects"

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Doeser, A., S. Riemann, T. Thiesler, C. Schiller, A. Mustea, G. Kristiansen, G. Hartmann, and K. Kübler. "CD117+/c-Kit+ cancer stem cells exhibit immune-modulatory effects in high-grade serous ovarian cancer." In Kongressabstracts zur Tagung 2020 der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe (DGGG). © 2020. Thieme. All rights reserved., 2020. http://dx.doi.org/10.1055/s-0040-1718130.

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Paterson, Samuel, Samuel Fernández-Tomé, and Blanca Hernández-Ledesma. "Modulatory Effects of a Lunasin-Enriched Soybean Extract on Immune Response and Oxidative Stress-Associated Biomarkers." In IECN 2022. Basel Switzerland: MDPI, 2022. http://dx.doi.org/10.3390/iecn2022-12367.

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Dowal, Louisa, Maria D. Nastke, Nidhi Gaur, Richa Singh, Samantha Fowler, Shyamali Jayashankar, Anne R. Diers, et al. "Abstract 703: The anti-cancer drug BPM 31510 elicits immune-modulatory effects through regulation of IL-10." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-703.

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Moon, Kyung-Sub, Derek A. Wainwright, Irina V. Balyasnikova, Chung Kwon Kim, Yoo Seung Ko, Kyung Keun Kim, and Maciej S. Lesniak. "Abstract LB-64: Immune modulatory effects of mesenchymal stem cells on regulatory T cells in mouse glioma model." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-lb-64.

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Sohn, IW, H.-J. Jeong, GY Ahn, MJ Kim, H. Kim, S. Kang, and DH Yoo. "AB0040 Immune modulatory effects of mesenchymal stem cell to mononuclear cells from patients with active adult onset still's disease." In Annual European Congress of Rheumatology, 14–17 June, 2017. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2017-eular.5719.

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Janakiram, Naveena B., Altaf Mohammed, Misty Brewer, Peter D. Collin, Vernon E. Steele, and Chinthalapally V. Rao. "Abstract 2145: Chemopreventive and immune-modulatory effects of the Cucumaria frondosa extract, Frondanol A5 in the APCMin/+ mice intestinal tumorigenesis." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-2145.

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Liu, C.-Y., K.-Y. Lau, J.-L. Chen, P.-Y. Chu, C.-T. Huang, W.-L. Wang, P.-J. Lien, and L.-M. Tseng. "Abstract P4-06-21: MEK inhibitor cobimetinib induces immunogenic cell death and immune-modulatory effects in triple negative breast cancer." In Abstracts: 2018 San Antonio Breast Cancer Symposium; December 4-8, 2018; San Antonio, Texas. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-p4-06-21.

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Tordesillas, Leticia, Rebecca Hesterberg, Ivannie Ortiz-Rivera, Brittney R. Sell, Omar Chavez Chiang, Kimberly T. Nguyen, Brian L. Murphy, Pearlie K. Burnette, Elsa R. Flores, and Kenneth Y. Tsai. "Abstract 1227: Immune modulatory effect of pramlintide for cutaneous squamous cell carcinoma treatment." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-1227.

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Tordesillas, Leticia, Rebecca Hesterberg, Ivannie Ortiz-Rivera, Brittney R. Sell, Omar Chavez Chiang, Kimberly T. Nguyen, Brian L. Murphy, Pearlie K. Burnette, Elsa R. Flores, and Kenneth Y. Tsai. "Abstract 1227: Immune modulatory effect of pramlintide for cutaneous squamous cell carcinoma treatment." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-1227.

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Braun, Donald P., Bani M. Fagla, and Irshad Ali. "Abstract 4284: The effect of resveratrol and curcumin on the expression of immune modulatory molecules on colorectal cancer cells." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-4284.

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