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Journal articles on the topic 'Immune System's'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Scanlon, Seth Thomas. "The immune system's first steps." Science 368, no. 6491 (2020): 598–99. http://dx.doi.org/10.1126/science.abc3140.

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2

Travis, J. "Tracing the immune system's evolutionary history." Science 261, no. 5118 (1993): 164–65. http://dx.doi.org/10.1126/science.8327890.

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3

Spatola, M., and R. A. Du Pasquier. "Immune system's role in viral encephalitis." Revue Neurologique 170, no. 10 (2014): 577–83. http://dx.doi.org/10.1016/j.neurol.2014.07.005.

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4

Leslie, Mitch. "The Immune System's Compact Genomic Counterpart." Science 339, no. 6115 (2013): 25–27. http://dx.doi.org/10.1126/science.339.6115.25.

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5

Bell, Elaine. "DCs: the immune system's flexible friend." Nature Reviews Immunology 3, no. 8 (2003): 604. http://dx.doi.org/10.1038/nri1155.

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6

Ehrenberg, Rachel. "Immunology: Fungi aid immune system's fight." Science News 173, no. 10 (2009): 157. http://dx.doi.org/10.1002/scin.2008.5591731016.

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7

Stefan, Riley. "Cancer Immunotherapy and its Benefit: An Editorial." Cancer Medicine Journal 1, no. 1 (2018): 37–38. http://dx.doi.org/10.46619/cmj.2018.1-1005.

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Cancer immunotherapy is also known as immuno-oncology which is the artificial activation of the immune system to fight against cancer, improving on the immune system's natural ability to fight the germs and disease causing cancer. Immunotherapy can be classified as into three categories such as active, passive and hybrid.

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8

Zhang, Zheng. "Analysis of fault self-healing in signal conditioning systems based on immune principles." Journal of Physics: Conference Series 3060, no. 1 (2025): 012034. https://doi.org/10.1088/1742-6596/3060/1/012034.

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Abstract In the study of fault self-healing in signal conditioning systems of electromechanical equipment, the traditional signal conditioning system is composed of an amplification circuit and a filtering circuit. This paper analyzes the structural characteristics, parameter properties, and typical fault features of the signal conditioning system and establishes a health factor group to assess the system's anti-aging performance. A model of the signal conditioning system is established, and the system's faults are analyzed. Simulation experiments on the fault self-healing of the signal condit

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Schild, Hansjörg, and Hans-Georg Rammensee. "gp96—The immune system's Swiss army knife." Nature Immunology 1, no. 2 (2000): 100–101. http://dx.doi.org/10.1038/77770.

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10

Lanzavecchia, Antonio. "Exploiting the immune system's own strategies for immunotherapy." Immunology Today 9, no. 6 (1988): 167–68. http://dx.doi.org/10.1016/0167-5699(88)91291-1.

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11

S.B., Borovkov, Rula O.M., and Usova L.P. "The Immunity Indicators in Horses During Vaccination and the Impact of Obesity on Their Formation." Bulletin "Veterinary biotechnology", no. 46 (June 12, 2025): 7–25. https://doi.org/10.31073/vet_biotech46-01.

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Horses, like all animals, rely on their immune systems to fight off infections and maintain overall health. Vaccination is one of the most effective methods for enhancing the immune response and protecting animals from infectious diseases. However, obesity is a growing concern in horses, and there is limited understanding of its effect on the immune system, especially in the context of vaccination. Obesity can lead to chronic inflammation and may alter the immune response. This research aims to investigate the immune indicators in horses during vaccination and evaluate the impact of obesity on

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12

McCusker, R. H., and K. W. Kelley. "Immune-neural connections: how the immune system's response to infectious agents influences behavior." Journal of Experimental Biology 216, no. 1 (2012): 84–98. http://dx.doi.org/10.1242/jeb.073411.

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13

Slepov, Y. K., M. A. Laushkin, and R. V. Deev. "The hipotises of the immune system's role in carcinogenesis." Genes & Cells 16, no. 1 (2021): 82–91. http://dx.doi.org/10.23868/202104013.

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The presented controversial hypothesis is an attempt to reflect on the role of the adaptive immune response in carcinogenesis. It is a well-known fact that the most of the signaling pathways which are participating in embryogenesis and regeneration are also active in tumor growth. Considering their presence in different evolutionary groups, there's such a contradiction that with same mechanisms of proliferation, animals with high regenerative potential are less predisposed to malignancy than mammals. Comparing these two groups, it's being discovered that despite the importance of immune contro

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14

Matzinger, P. "The immune system's role in graft loss: Theoretic considerations." Transplantation Proceedings 29, no. 8 (1997): 11S—12S. http://dx.doi.org/10.1016/s0041-1345(97)00848-8.

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15

Bird, Lucy. "Another way to escape the immune system's watchful eye." Nature Reviews Immunology 5, no. 9 (2005): 673. http://dx.doi.org/10.1038/nri1698.

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16

Bonney, E. A., and P. Matzinger. "The maternal immune system's interaction with circulating fetal cells." Journal of Immunology 158, no. 1 (1997): 40–47. http://dx.doi.org/10.4049/jimmunol.158.1.40.

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Abstract Although female mice readily reject organs from allogeneic or semiallogeneic male donors, they do not reject the fetuses sired by those same donors. An explanation for this that has been made in the past is that the fetus influences its mother's immune response by sending fetal cells into the maternal circulation. To determine the frequency and magnitude of fetal to maternal cell migration, we employed a sensitive quantitative PCR technique to assess the numbers of male cells in the thymus, spleen, liver, lymph nodes, and peripheral blood of normal mice undergoing their first pregnanc

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17

Raimov, Khamid Soatovich. "FEATURES OF THE IMMUNE SYSTEM OF WOMEN DURING SPORTS ACTIVITIES." Modern Scientific Research International Scientific Journal 2, no. 4 (2024): 220–26. https://doi.org/10.5281/zenodo.11194559.

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The article provides a brief description of diametrically opposed views on the role of physical activity on human health, whether health-improving or negative. In recent decades, the functional unity of the central nervous system, endocrine and immune systems has been established, which are defined as the neuroendocrine-immune system. The nature of the system's reaction under conditions of physical activity depends not only on their magnitude and intensity, but also on the intensity of their psycho-emotional accompaniment, which is typical for modern elite sports.

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18

Mohammad Alsudairy, Najlaa, Sultanah Sameer Ibrahim Saeedi, Nourah Abdullah Alfarhan, et al. "Effect of Ageing on The Immune System, A Review." Saudi Medical Horizons Journal 2, no. 2 (2022): 36–41. http://dx.doi.org/10.54293/smhj.v2i2.43.

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The immune system's performance declines as we age, increasing our vulnerability to illnesses and perhaps lowering our quality of life. Stress and normal ageing both cause a decline in immune function. Social and psychological pressures are a regular component of life and the cause of significant events that alter direction. Throughout their lives, people are exposed to a variety of stressors, with effects that develop at various rates due to differences in stress exposure, stress buffering, stress reactivity, stress duration (recovery), and restorative mechanisms. The consequences of these pr

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Streit, Wolfgang J., Jessica R. Conde, Sarah E. Fendrick, Barry E. Flanary, and Christopher L. Mariani. "Role of microglia in the central nervous system's immune response." Neurological Research 27, no. 7 (2005): 685–91. http://dx.doi.org/10.1179/016164105x49463a.

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20

Shu, Chengyi Jenny, Christophe Benoist, and Diane Mathis. "The immune system's involvement in obesity-driven type 2 diabetes." Seminars in Immunology 24, no. 6 (2012): 436–42. http://dx.doi.org/10.1016/j.smim.2012.12.001.

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21

Sagay-Omonogor, Irene, Tolulope Bolarinwa, and Opeoluwa Oluwanifemi Akomolafe. "Overcoming Challenges in Cancer Immunotherapy: Mechanisms and Clinical Solutions." International Journal of Multidisciplinary Research and Growth Evaluation 4, no. 2 (2023): 883–88. https://doi.org/10.54660/.ijmrge.2023.4.2.883-888.

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Cancer immunotherapy has revolutionized oncology by harnessing the immune system's inherent ability to recognize and eliminate tumor cells. This review explores the mechanisms, challenges, clinical solutions, and future directions of cancer immunotherapy. Mechanistic insights into immune checkpoint inhibitors, CAR-T cell therapy, and cancer vaccines are discussed, highlighting their roles in enhancing anti-tumor immune responses. Challenges such as tumor immune evasion, adverse effects management, patient-specific variability, and resistance mechanisms are examined, alongside clinical strategi

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22

Robertsson, Ivan, Orvar Gunnarsson, Elsa Jonsdottir, Agnes Smaradottir, and Sigurdis Haraldsdottir. "Úlfur í sauðargæru – birtingarmynd og fjölbreytileiki aukaverkana með ónæmisörvandi krabbameinslyfjameðferð." Laeknabladid 111, no. 07/08 (2025): 318–24. https://doi.org/10.17992/lbl.2025.0708.849.

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Immunotherapy, particularly immune checkpoint inhibitors, has significantly impacted cancer treatment by enhancing the immune system's ability to identify and attack cancer cells. However, this treatment introduces unique immune-related adverse events (irAEs), which require careful management due to their potential to affect multiple organ systems. IrAEs can manifest during or after treatment, affecting organs such as the gastrointestinal tract, endocrine glands, lungs, and liver, with symptoms ranging from mild to life threatening. While irAEs are distinct from those seen in traditional cance

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23

Izadiyan, Zahra, Katayoon Kalantari, and Kamyar Shameli. "Investigation of Advanced Nanoscale Biomaterials as Immune Modulators for Therapeutic Applications." Journal of Research in Nanoscience and Nanotechnology 13, no. 1 (2024): 33–44. http://dx.doi.org/10.37934/jrnn.13.1.3344.

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Immunomodulatory agents play a crucial role in drug delivery by modulating the immune system's response to therapeutic agents, thereby enhancing treatment efficacy and safety. These agents can either stimulate the immune system to improve drug effectiveness, particularly in cancer and infectious diseases, or suppress it to prevent adverse reactions in conditions like organ transplantation and autoimmune diseases. The integration of immunomodulatory agents into drug delivery systems (DDS) enhances drug targeting, controls release, and optimizes pharmacokinetics. Advanced carriers such as nanopa

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24

Wahl, Angela, and J. Victor Garcia. "Humanized Mouse Systems to Study Viral Infection: A New Era in Immunology Research." Annual Review of Immunology 43, no. 1 (2025): 143–67. https://doi.org/10.1146/annurev-immunol-082223-035718.

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For decades, scientists have relied on traditional animal models to study viral infection and the immune response. However, these models have limitations, and the search for more accurate and reliable ways to study the human-pathogen interphase has led to the development of humanized mouse systems. These revolutionary models have transformed how we understand viral infection and the human immune system's interactions with viruses to control or exacerbate disease. They are also paving the way for new treatments and therapies. In this article, we explore the history and development of humanized

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25

Schmidt, Charlie. "Immune System's Toll-like Receptors Have Good Opportunity for Cancer Treatment." JNCI: Journal of the National Cancer Institute 98, no. 9 (2006): 574–75. http://dx.doi.org/10.1093/jnci/djj198.

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26

Jones, Christopher M. "Failing to adapt – the ageing immune system's role in cancer pathogenesis." Reviews in Clinical Gerontology 21, no. 3 (2011): 209–18. http://dx.doi.org/10.1017/s0959259811000037.

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SummaryA person's risk of developing cancer rises exponentially with age, an increase that is widely considered to result from cumulative exposure to mutagenic agents. However, cancer incidence rates decelerate and plateau beyond 85 years of age and numerous malignant pathologies peak in incidence during early or middle life, indicating an important role for additional factors in controlling the timing and nature of cancer development. Given that immune function is known to decrease with age, malignant neoplastic change may be induced by increased chronic infection and the onset of a pervasive

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27

FENTON, ANDY, and SARAH E. PERKINS. "Applying predator-prey theory to modelling immune-mediated, within-host interspecific parasite interactions." Parasitology 137, no. 6 (2010): 1027–38. http://dx.doi.org/10.1017/s0031182009991788.

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SUMMARYPredator-prey models are often applied to the interactions between host immunity and parasite growth. A key component of these models is the immune system's functional response, the relationship between immune activity and parasite load. Typically, models assume a simple, linear functional response. However, based on the mechanistic interactions between parasites and immunity we argue that alternative forms are more likely, resulting in very different predictions, ranging from parasite exclusion to chronic infection. By extending this framework to consider multiple infections we show th

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28

Asadi, Saeid, Vahid Azimirad, Ali Eslami, and Saeid Karimian Eghbal. "Immune–wavelet optimization for path planning of large-scale robots." Robotica 32, no. 1 (2013): 77–95. http://dx.doi.org/10.1017/s0263574713000635.

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SUMMARYIn this paper an optimal path planning method based on a new evolutionary algorithm is presented for higher order robotic systems. It is a combination of immune system and wavelet mutation. By increasing the system's dimensions, the complexity of algorithm grows linearly. The obtained results have been compared with other optimal path producing algorithms, and its excellence in terms of optimality has been proved. Strengths of this method are simplicity in large-scale path planning, being free of most of the common deadlocks in usual method, and ability to obtain more optimized results

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29

Farideh, Shojaee* and Hamid Sadeghi Rine. "INVESTIGATE THE EFFECT OF STRENGTH EXERCISES ON THE IMMUNE SYSTEM'S PERFORMANCE OF ATHLETES IN THE BODY BUILDING CLUBS OF NORTHERN TEHRAN, 2012." Indo American Journal of Pharmaceutical Sciences 04, no. 11 (2017): 3987–90. https://doi.org/10.5281/zenodo.1043934.

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Exercise is one of the important factors in the prevention, treatment and maintenance of mental and physical health. The immune system is one of the vital systems, the proper functioning of which guarantees the health of individuals. The aim of this study is to investigate the effect of strength exercises on the immune system's performance of athletes in the bodybuilding clubs of northern Tehran in 2012. The study is a randomized-clinical trial, in which 96 athletes from northern Tehran were surveyed in 2012. Demographic data and disease history was collected through a researcher-made question

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30

Kim, Seong-Gon. "Special Issue on Immunomodulation and Smart Materials for the Application of Maxillofacial Surgery." Applied Sciences 13, no. 9 (2023): 5734. http://dx.doi.org/10.3390/app13095734.

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Immunomodulation in tissue engineering involves the deliberate manipulation or regulation of the immune system's response to aid in tissue regeneration, repair, or the incorporation of engineered constructs within the body [...]

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31

Zarei, Hassan, Ali Vahidian Kamyad, and Ali Akbar Heydari. "Fuzzy Modeling and Control of HIV Infection." Computational and Mathematical Methods in Medicine 2012 (2012): 1–17. http://dx.doi.org/10.1155/2012/893474.

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The present study proposes a fuzzy mathematical model of HIV infection consisting of a linear fuzzy differential equations (FDEs) system describing the ambiguous immune cells level and the viral load which are due to the intrinsic fuzziness of the immune system's strength in HIV-infected patients. The immune cells in question are considered CD4+ T-cells and cytotoxic T-lymphocytes (CTLs). The dynamic behavior of the immune cells level and the viral load within the three groups of patients with weak, moderate, and strong immune systems are analyzed and compared. Moreover, the approximate explic

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32

Saleem, Omer, Mohsin Rizwan, and Fahim Gohar Awan. "Robustification of the state-space MRAC law for under-actuated systems via fuzzy-immunological computations." Science Progress 105, no. 3 (2022): 003685042211222. http://dx.doi.org/10.1177/00368504221122291.

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This paper formulates an enhanced Model-Reference-Adaptive-Controller (MRAC) that is augmented with a fuzzy-immune adaptive regulator to strengthen the disturbance-attenuation capability of closed-loop under-actuated systems. The proposed scheme employs the conventional state-space MRAC and augments it with a pre-configured fuzzy-immune mechanism that acts as a superior regulator to dynamically modulate the adaptation gains of the Lyapunov gain-adjustment law. The immunological computations increase the controller's adaptability to flexibly manipulate the damping control effort under exogenous

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33

Postow, Michael A. "Managing Immune Checkpoint-Blocking Antibody Side Effects." American Society of Clinical Oncology Educational Book, no. 35 (May 2015): 76–83. http://dx.doi.org/10.14694/edbook_am.2015.35.76.

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Immune checkpoint-blocking antibodies that enhance the immune system's ability to fight cancer are becoming important components of treatment for patients with a variety of malignancies. Cytotoxic T-lymphocyte–associated antigen 4 (CTLA-4) was the first immune checkpoint to be clinically targeted, and ipilimumab, an inhibitor of CTLA-4, was approved by the U.S. Food and Drug Administration (FDA) for patients with advanced melanoma. The programmed cell death-1 (PD-1) receptor and one of its ligands, PD-L1, more recently have shown great promise as therapeutic targets in a variety of malignancie

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34

Vivekanandan, K. "Current Trends of Immune System Engineering in Healthcare Applications." December 2022 1, no. 1 (2022): 26–37. http://dx.doi.org/10.36548/rrrj.2022.1.003.

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Immune system engineering presents significant challenges as well as great opportunities for biomedical engineers. Human immunity is critical to both health and disease, and immune system activation plays a critical role in disease prevention. The malfunctioning of the human immune system will result in autoimmune disorders, cardiovascular disease, cancer, and other serious diseases. Immune engineering responds to the immune system's complex challenges by targeting a variety of cellular and molecular processes, such as improving antigen presentation, reviving worn-out tumour cells, engineering

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Vivekanandan, K. "Current Trends of Immune System Engineering in Healthcare Applications." December 2022 1, no. 1 (2022): 26–37. http://dx.doi.org/10.36548/rrrj.2023.1.003.

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Immune system engineering presents significant challenges as well as great opportunities for biomedical engineers. Human immunity is critical to both health and disease, and immune system activation plays a critical role in disease prevention. The malfunctioning of the human immune system will result in autoimmune disorders, cardiovascular disease, cancer, and other serious diseases. Immune engineering responds to the immune system's complex challenges by targeting a variety of cellular and molecular processes, such as improving antigen presentation, reviving worn-out tumour cells, engineering

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36

Delano, Matthew J., and Peter A. Ward. "The immune system's role in sepsis progression, resolution, and long-term outcome." Immunological Reviews 274, no. 1 (2016): 330–53. http://dx.doi.org/10.1111/imr.12499.

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37

Ironson, Gail, Tiffany Field, Frank Scafidi, et al. "Massage Therapy is Associated with Enhancement of the Immune System's Cytotoxic Capacity." International Journal of Neuroscience 84, no. 1-4 (1996): 205–17. http://dx.doi.org/10.3109/00207459608987266.

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38

RUPADEVI, RUPADEVI. "Optimal Drug Dosage Control in Immune Systems Using Machine Learning." International Scientific Journal of Engineering and Management 04, no. 04 (2025): 1–7. https://doi.org/10.55041/isjem03033.

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Abstract: This study combines supervised machine learning and reinforcement learning techniques to present a novel framework for individualized drug dosage prediction. To suggest dosage levels that maximize recovery while minimizing side effects, we have devised a system that evaluates patient-specific characteristics, such as the severity of the illness, the immune system's reaction, and the present drug concentration. Our hybrid strategy combines adaptive reinforcement learning systems with conventional predictive models that can change dose in real time. According to testing data, our metho

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Darmadi, Eveline Yulia, and Yessy Andriani Fauziah. "The synergistic role of the immune system and stem cells in dental tissue regeneration." Conservative Dentistry Journal 15, no. 1 (2025): 18–22. https://doi.org/10.20473/cdj.v15i1.2025.18-22.

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Background: Dental conservation focuses on maintaining natural teeth structure, function, and aesthetics using various techniques. Recent developments in regenerative dentistry highlight the immune system's and stem cells' crucial roles in regenerating dental tissues. The immune system is key in preserving oral health and supporting healing after treatment. Incorporating stem cell therapy presents a promising strategy for restoring damaged tissues, potentially enhancing the effectiveness of dental conservation. Purpose: This review explores the growing potential of immune system modulation and

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40

Wu, Mei Mei. "The Application and Realization of Active Database in Computer Immune System." Applied Mechanics and Materials 432 (September 2013): 549–54. http://dx.doi.org/10.4028/www.scientific.net/amm.432.549.

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In this paper we introduce a kind of management mechanism for computer immune system GECISM (GEneral Computer Immune System Model)[. With it when emergency happens it can be timely and actively response according to the current state of database. Thus it improved the executive efficiency of the computer immune system. The method is that we design the local rules in the form of active database. It neednt user intervention for the processes to be handled by the processor. The database of the client machine can automatically carry out the judgment of "self" and "non-self". So it can improve the s

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41

Ravi, Meghna, Andrew H. Miller, and Vasiliki Michopoulos. "The immunology of stress and the impact of inflammation on the brain and behaviour." BJPsych Advances 27, no. 3 (2021): 158–65. http://dx.doi.org/10.1192/bja.2020.82.

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SUMMARYExposure to acute versus chronic stressors and threats activates the immune system in adaptive and maladaptive manners respectively. Chronic activation arising from persistent stress exposure can contribute to an inflammatory response in the periphery and in the brain that has been implicated in stress-related psychopathology, including depression and anxiety. We review the immunology of acute and chronic stress exposure, integrate this discussion with the emerging literature linking heightened immune activation and inflammation to mood and anxiety disorders, and consider the translatio

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Safia, Imadoudini Hassimi, Yao-Yun Tang, Wu Ping, and Jiang Jie. "Harnessing Photo-Dynamic Treatment for Immune System Diseases: A Promising Therapeutic Approach: A Systematic Review." EAS Journal of Medicine and Surgery 6, no. 03 (2024): 105–14. http://dx.doi.org/10.36349/easjms.2024.v06i03.005.

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Photodynamic treatment (PDT) has emerged as a promising therapeutic approach for immune system diseases due to its ability to selectively target abnormal cells while modulating the immune response. This review explores the mechanisms by which PDT activates the immune system to target diseased cells, including the induction of immunogenic cell death, activation of dendritic cells, release of tumor-associated antigens, modulation of immune checkpoints, and induction of cytokines and chemokines. Additionally, PDT can generate reactive oxygen species, induce apoptosis, and exhibit anti-inflammator

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Diaz, Pablo, Michael Gillespie, Justin Krueger, et al. "A Mathematical Model of the Immune System's Role in Obesity-Related Chronic Inflammation." SIAM Undergraduate Research Online 2, no. 2 (2009): 26–45. http://dx.doi.org/10.1137/08s010323.

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Fu, Yeqin, Qiuhui Yang, Ning Xu, and Xiping Zhang. "MiRNA affects the advancement of breast cancer by modulating the immune system's response." Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1871, no. 5 (2025): 167759. https://doi.org/10.1016/j.bbadis.2025.167759.

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45

J S, Sreevidhya. "Homoeopathic Approach in Treating Vitiligo: Review Article." International Journal of Research and Review 10, no. 7 (2023): 779–82. http://dx.doi.org/10.52403/ijrr.20230791.

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An autoimmune condition is vitiligo. Due to internal immune system failure, it manifests externally as a skin condition. Therefore, rather than applying anything externally, the treatment should focus on addressing the immune system's imbalance, which is its underlying cause. In most cases of vitiligo, homeopathy provides great treatment because it adheres to the same premise. Here, an effort is made to explain the causes of vitiligo and the homoeopathic method to treating it. Keywords: Melanocytes, Skin color, Focal areas, autoimmune disease

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Jan, Rahila, Dr Nitin Agarwal, Dr Payal Tripathi, Dr Neha Agarwal, Dr Krishankant Chaudhary, and Dr Somi Fatima. "Oral Mucosal Manifestations of Autoimmune Disorders: A Review." EAS Journal of Dentistry and Oral Medicine 4, no. 6 (2022): 141–46. http://dx.doi.org/10.36349/easjdom.2022.v04i06.002.

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Immunity is the ability of the body to defend itself against infectious diseases. The immune system has developed to protect the host from a continually evolving universe of dangerous bacteria. In addition, the immune system aids the host in the elimination of hazardous substances or allergenic chemicals that enter the body through the mucosal membranes. Autoimmunity is characterised by disruptions in the immune system's control at multiple levels. To avoid the onset of autoimmunity, self-tolerance and discrimination between self and non- self work together. Tolerance is produced and maintaine

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47

Casanova, Jean-Laurent, and Laurent Abel. "Inborn errors of immunity to infection." Journal of Experimental Medicine 202, no. 2 (2005): 197–201. http://dx.doi.org/10.1084/jem.20050854.

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The immune system's function is to protect against microorganisms, but infection is nonetheless the most frequent cause of death in human history. Until the last century, life expectancy was only ∼25 years. Recent increases in human life span primarily reflect the development of hygiene, vaccines, and anti-infectious drugs, rather than the adjustment of our immune system to coevolving microbes by natural selection. We argue here that most individuals retain a natural vulnerability to infectious diseases, reflecting a great diversity of inborn errors of immunity.

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48

Hao, Xinyuan. "Cytokine IL-12 Based Cancer Immunotherapy." Highlights in Science, Engineering and Technology 74 (December 29, 2023): 1667–73. http://dx.doi.org/10.54097/53anz541.

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Immunotherapy is an important method in cancer therapy. Cytokines are signaling molecules produced by the immune system that play a crucial role in regulating immune responses. They can be harnessed in immunotherapy to modulate the immune system's activity to treat various diseases, including cancer and autoimmune disorders. It has been confirmed that Interleukin-12 (IL-12) family cytokines play an important role in tumor immune regulation. Different cytokines in the IL-12 family have different effects and regulatory roles. The IL-12 family of cytokines has shown promise in cancer immunotherap

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49

Glickman, Matthew, Justin Balthrop, and Stephanie Forrest. "A Machine Learning Evaluation of an Artificial Immune System." Evolutionary Computation 13, no. 2 (2005): 179–212. http://dx.doi.org/10.1162/1063656054088503.

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ARTIS is an artificial immune system framework which contains several adaptive mechanisms. LISYS is a version of ARTIS specialized for the problem of network intrusion detection. The adaptive mechanisms of LISYS are characterized in terms of their machine-learning counterparts, and a series of experiments is described, each of which isolates a different mechanism of LISYS and studies its contribution to the system's overall performance. The experiments were conducted on a new data set, which is more recent and realistic than earlier data sets. The network intrusion detection problem is challen

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Mukherjee, Sumon, Saikat Dutta, Subhadip Pati, et al. "Nuclear factor kappa-B: The El Dorado of inflammatory immune response." Journal of Cellular and Molecular Immunology 3, no. 1 (2024): 6–19. http://dx.doi.org/10.46439/immunol.3.025.

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Abstract:

For more than a decade, the nuclear factor kappa-B (NFκB) family and their signaling pathways have proved crucial to the immune system's functioning. According to research, this factor is implicated in almost every immune system event, including immune cell development and function, activation, and pathogen-activated cell death. A considerable body of evidence suggests the idea that, in addition to being a possible transcription factor, it plays a very significant role in the establishment of inflammation-associated immunological responses in host cells. Inflammation is a cascade of events tha

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