Academic literature on the topic 'Immune system and lung affections'

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Journal articles on the topic "Immune system and lung affections"

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Flaviano, Sandoval Maldonado, Cesar Lomelí Omar, Vigil Gerardo, Arredondo Robledo Verónica, Gabriel López Hernandez Juan, and Estela Vargas Rios Silvia. "Correlation of Aggressive Environments and Operative Yielding of Manufacturing workers in an Electronics Industry of Mexicali." Partners Universal International Research Journal (PUIRJ) ISSN: 2583-5602 01, no. 04 (2022): 175–81. https://doi.org/10.5281/zenodo.7512208.

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<em>This investigation was made to evaluate the correlation analysis of the presence of aggressive environments in indoor of an electronics industry installed in the Mexicali city, and its negative effect in low yielding of workers of the manufacturing areas, due to its weakened immune system and lung affections. This originated the generation of respiratory diseases as flu as the most common acute respiratory symptom in some workers, being the principal factor of a decrement of its productivity and quality levels. One of the relevant factors of this serious health symptom is the exposure to p
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Albright, Joseph F., and Robert A. Goldstein. "Airborne Pollutants and the Immune System." Otolaryngology–Head and Neck Surgery 114, no. 2 (1996): 232–38. http://dx.doi.org/10.1016/s0194-59989670173-0.

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The effects of airborne pollutants on the immune system have been most widely studied in the respiratory tract. Entry may occur as a volatile gas (ozone, benzene), as liquid droplets (sulfuric acid, nitrogen dioxide), or as particulate matter (diesel exhaust, aromatic hydrocarbons). The subsequent interaction with the immune system may result in local and systemic responses, and studies have shown examples of disease occurring from both overactive immune responses and immunosuppression. For the most part, airborne pollutants (small molecular weight chemicals) have to be coupled with other subs
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Nascimento, Amanda, Upkar Pandher, Brooke Thompson, David Schneberger, Baljit Singh, and Shelley Kirychuk. "Exploring the Immunomodulatory Potential of Natures Immuno: A Study on Mushroom Formulations in Alleviating LPS-Induced Inflammation." Journal of Immunology 212, no. 1_Supplement (2024): 1066_5569. http://dx.doi.org/10.4049/jimmunol.212.supp.1066.5569.

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Abstract Introduction: Inflammatory diseases, such as pulmonary inflammation, lung cancer, and asthma, pose a significant global economic impact, affecting health and quality of life. Proinflammatory cytokines released by the immune system can be activated by Lipopolysaccharides (LPS), an endotoxin mimicking infection by Gram-negative bacteria. Literature suggests an increased risk of inflammatory diseases in females compared to males. Natures Immuno, a formulation extracted from five commonly used mushrooms (Turkey Tail, Cordyceps, Reishi, Shiitake, and Agaricus), aims to address this issue.
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Synodinou, Kalliopi D., Maroulla D. Nikolaki, Konstantinos Triantafyllou, and Arezina N. Kasti. "Immunomodulatory Effects of Probiotics on COVID-19 Infection by Targeting the Gut–Lung Axis Microbial Cross-Talk." Microorganisms 10, no. 9 (2022): 1764. http://dx.doi.org/10.3390/microorganisms10091764.

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The ecosystem of the human gastrointestinal tract, named gut microbiota, represents the most thoroughly mapped ecosystem. Perturbations on bacterial populations cause dysbiosis, a condition correlated to a wide range of autoimmune, neurological, metabolic, cardiovascular, and respiratory diseases. The lungs have their flora, which are directly related to the gut flora via bidirectional communication allowing the transport of microbial metabolites and toxins produced by intestinal bacteria through the circulation and lymphatic system. This mutual microbial cross-talk communication called the gu
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Saigí, Maria, Oscar Mesía-Carbonell, David A. Barbie, and Raquel Guillamat-Prats. "Unraveling the Intricacies of CD73/Adenosine Signaling: The Pulmonary Immune and Stromal Microenvironment in Lung Cancer." Cancers 15, no. 23 (2023): 5706. http://dx.doi.org/10.3390/cancers15235706.

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CD73 and adenosine have gained prominence in lung cancer research. The NT5E gene encodes CD73, known as an ectonucleotidase, which plays a crucial role within tumor cells, with immune-suppressive properties. Beyond cancer, CD73 exerts an influence on cardiac, neural, and renal functions, affecting cardiac, neural, and renal functions. CD73’s significance lies in its production of extracellular adenosine. It is notably expressed across diverse cell types within the immune and stromal lung microenvironment. CD73 expression amplifies in lung tumors, especially non-small cell lung cancer (NSCLC),
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Chunxi, Li, Liu Haiyue, Lin Yanxia, Pan Jianbing, and Su Jin. "The Gut Microbiota and Respiratory Diseases: New Evidence." Journal of Immunology Research 2020 (July 31, 2020): 1–12. http://dx.doi.org/10.1155/2020/2340670.

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Human body surfaces, such as the skin, intestines, and respiratory and urogenital tracts, are colonized by a large number of microorganisms, including bacteria, fungi, and viruses, with the gut being the most densely and extensively colonized organ. The microbiome plays an essential role in immune system development and tissue homeostasis. Gut microbiota dysbiosis not only modulates the immune responses of the gastrointestinal (GI) tract but also impacts the immunity of distal organs, such as the lung, further affecting lung health and respiratory diseases. Here, we review the recent evidence
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Heydari Sheikhhossein, Hamid, Luisa Amato, Viviana De Rosa та ін. "Effect of IL-1β on NSCLC-Derived Small Extracellular Vesicles as Actors in Mediating Cancer Progression and Evading Immune System". International Journal of Molecular Sciences 26, № 14 (2025): 6825. https://doi.org/10.3390/ijms26146825.

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Background: Increased IL-1β levels may promote carcinogenesis and metastasis by affecting tumor biology and the tumor microenvironment (TME). In this context, extracellular vesicles (EVs) play a key role in cell-to-cell communication, thus modulating the TME and immune response. Here, we aimed to test whether tumor-derived small EVs (TEVs) isolated from sensitive and osimertinib-resistant (OR) non-small-cell lung cancer (NSCLC) cells may promote EMT via fibronectin binding to α5β1 integrin as well as suppress the immune system and if these effects may be favored by IL-1β. Methods: TEVs were is
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Laamech, Reda, Florian Terrec, Camille Emprou, et al. "Efficacy of Plasmapheresis in Nivolumab-Associated ANCA Glomerulonephritis: A Case Report and Pathophysiology Discussion." Case Reports in Nephrology and Dialysis 11, no. 3 (2021): 376–83. http://dx.doi.org/10.1159/000518304.

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Immune checkpoint inhibitors (ICIs) have revolutionized solid organ and hematologic cancer treatments by improving overall prognoses. However, they can lead to overactivation of the immune system and several immune-related adverse events and sometimes affecting the renal system. Although acute interstitial nephritis is well described, we know little about ICI-associated glomerular injury. Herein, we report an exceptional case of renal ANCA positive-associated vasculitis (AAV) after nivolumab therapy. Three weeks after the last nivolumab injection, the patient presented with proteinuria at 1.73
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Tana, Claudio, Francesco Cinetto, Cesare Mantini, et al. "Sarcoidosis and COVID-19: At the Cross-Road Between Immunopathology and Clinical Manifestation." Biomedicines 10, no. 10 (2022): 2525. http://dx.doi.org/10.3390/biomedicines10102525.

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Coronavirus disease 2019 (COVID-19) has been associated with dysregulation of the immune system featuring inappropriate immune responses, exacerbation of inflammatory responses, and multiple organ dysfunction syndrome in patients with severe disease. Sarcoidosis, also known as Besnier–Boeck–Schaumann disease, is an idiopathic granulomatous multisystem disease characterized by dense epithelioid non-necrotizing lesions with varying degrees of lymphocytic inflammation. These two diseases have similar clinical manifestations and may influence each other at multiple levels, eventually affecting the
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Barnett, James S., Kevin K. Yu, Xavier Rivera Rivera, and Asmeen Bhatt. "Severe Dysphagia With Eosinophilic Esophagitis Pattern of Injury Related to Pembrolizumab Therapy." ACG Case Reports Journal 11, no. 1 (2024): e01252. http://dx.doi.org/10.14309/crj.0000000000001252.

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ABSTRACT While immune checkpoint inhibitor (ICI) therapies are effective treatments for many cancers, ICI therapies are associated with immune-related adverse events. We present a 67-year-old man with non–small cell lung carcinoma, who developed severe dysphagia with biopsies from an esophagogastroduodenoscopy showing histopathology consistent with eosinophilic esophagitis while on ICI maintenance therapy with pembrolizumab. The patient's symptoms worsened despite standard therapy. However, he had complete resolution of dysphagia symptoms once pembrolizumab was discontinued. While immune-relat
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Dissertations / Theses on the topic "Immune system and lung affections"

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Lim, Boon-Leong. "Cloning and expression of a C1q-binding protein and two of the collections (Collectin-43 and lung surfactant protein D)." Thesis, University of Oxford, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239328.

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Kang, Nayon. "EFFECTS OF IN UTERO NICOTINE EXPOSURE ON IMMUNE CELL DISPOSITION AFTER P. AERUGINOSA LUNG INFECTION." UKnowledge, 2017. http://uknowledge.uky.edu/pharmacy_etds/79.

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Current smoking cessation guidelines recommend nicotine replacement therapy (NRT) to assist pregnant smokers to quit, but this is without strong evidence for effectiveness and safety. Nicotine, the main addictive component of tobacco, is known to exert physiological effects by binding to its receptor, the nicotinic acetylcholine receptor (nAChR). Recent studies have identified the presence of nAChRs in non-neuronal cells, and in macrophages, functional alteration upon stimulation with nicotine has been documented. To understand the impact of in utero nicotine exposure on various immune cell di
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Hutton, Andrew J. "Characterisation of the human lung fibroblasts ability to act as an antigen presenting cell for T helper cells of the immune system." Thesis, University of Southampton, 2015. https://eprints.soton.ac.uk/416623/.

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T helper cells of the immune system are critical in mediating immune responses in the lung. Through the release of cytokines, T helper cells direct the wider immune response against a range of pathogens and are considered indispensible for effective immunity. T cell activation is governed by the interaction with antigen-presenting cells (APCs), which mediate antigen-specific T cell activation and thus control immune responses in areas such as the lung. While T helper cell activation by APCs such as dendritic cells is well established, the role of fibroblasts in T helper cell activation in the
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NASH, JAMES ANDREW. "THE PEPTIDOGLYCAN-DEGRADING PROPERTY OF LYSOZYME IS NOT REQUIRED FOR BACTERICIDAL ACTIVITY, IN VIVO." University of Cincinnati / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1135957476.

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Vermaak, Ernst. "The influence of a nutritional supplement on lung function and immune status of hiv-positive patients in the Mangaung metropolitan." Thesis, Bloemfontein: Central University of Technology, Free State, 2013. http://hdl.handle.net/11462/252.

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Thesis (D. Tech. (Clinical Technology )) - Central University of Technology, Free State, 2013<br>The HIV pandemic in South-Africa has created a new form of vulnerability for households with regards to food security and nutritional status which are vital components in the general care of HIV-infected individuals. The risk of nutritional deficiencies and malnutrition are predictors of disease progression and treatment in resource limited settings. Furthermore, HIV affects nutritional status by increasing the energy requirements, reducing food intake, affecting nutrient absorption and metab
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Seneda, Ana Laura. "Perfil de expressão de microRNAs e análise computacional de vias moleculares moduladas por microRNAs em tumor carcinoide de pulmão." Botucatu, 2019. http://hdl.handle.net/11449/180860.

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Orientador: Patricia Pintor dos Reis<br>Resumo: Introdução: O tumor carcinoide do pulmão pertence ao tipo neuroendócrino das neoplasias pulmonares. Devido à sua baixa incidência (~2%), pouco se conhece sobre suas alterações moleculares. Os microRNAs (miRNAs) têm importante papel na regulação gênica e têm sido associados ao câncer como biomarcadores diagnósticos, prognósticos e preditivos. Objetivos: Determinar o perfil global de expressão de miRNAs em tumores carcinoides do pulmão e identificar (in silico) vias moleculares envolvendo os miRNAs desregulados e genes-alvo preditos. Material e Mét
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Vitoretti, Luana Beatriz. "Estudo de mecanismos reguladores da inflamação pulmonar tardia após isquemia e reperfusão intestinal em ratos." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/42/42136/tde-20022015-140750/.

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Citocinas geradas durante a I/R-i promovem lesão pulmonar aguda e podem causar imunossupressão. Investigamos se a inflamação pulmonar após dias de reperfusão intestinal está relacionada com alterações no sistema imune. Ratos machos Wistar foram submetidos a oclusão da artéria mesentérica superior por 45 min e a 2 h, 3, 5 ou 20 dias de reperfusão. Observamos que após 5 dias de reperfusão intestinal enterobactérias estão presentes nos linfonodos mesentéricos e que os neutrófilos circulantes estão mais ativos no combate a patógenos, enquanto leucócitos da cavidade peritoneal não. Notamos aumento
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Lindsay, Angus John Chisholm. "Acute and chronic individualised psychophysiological stress assessment of elite athletes through non-invasive biochemical analysis." Thesis, University of Canterbury. School of Biological Sciences, 2015. http://hdl.handle.net/10092/10737.

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Intense exercise is known to cause alterations in the psychophysiological status of an athlete. Monitoring the health and recovery of an athlete is imperative for the maintenance of performance and reduced fatigue and injury incidence. The physicality associated with select sports results in significant elevations and suppression of psychophysiological biomarkers that are often modulated by game-related impacts, intense training regimes and psychosocial aspects associated with the professional era. The aim of the studies outlined in this thesis were to determine the effectiveness of selecte
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"Pentraxin 3 in the lung and neutrophils." Thesis, 2013. http://hdl.handle.net/10388/ETD-2013-08-1195.

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Respiratory diseases are a major cause of human morbidity and mortality and are a leading cause of economic loss to livestock producers. The respiratory tract is constantly in contact with dust, bacteria, fungi, viruses and other pathogenic agents that are found in the air. Normally, the body has the ability to clear these foreign particles. However, physiological and environmental stresses can impair airway defense mechanisms resulting in establishment of pulmonary infections. The microbes and their products engage various receptors in the lung to activate epithelium, endothelium, macroph
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Bento, Daniela Filipa Almeida. "Monitorização Imunológica da Terapia com Inibidores dos Checkpoints Imunológicos em pacientes com Cancro do Pulmão." Master's thesis, 2018. http://hdl.handle.net/10316/82277.

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Trabalho Final do Mestrado Integrado em Medicina apresentado à Faculdade de Medicina<br>Introdução: Atualmente o cancro do pulmão é a principal causa de morte mundial por patologia oncológica e o subtipo de células não pequenas (CPNPC) a forma predominante da doença, sendo fundamental o desenvolvimento de uma terapia que prolongue significativamente a sobrevivência do doente, sem comprometer a qualidade de vida. Nesse sentido, nos últimos anos a imunoterapia com o recurso a inibidores de checkpoints imunológicos tornou-se numa área primária de interesse clínico no tratamento do CPNPC.Objetivos
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Books on the topic "Immune system and lung affections"

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F, Tenholder Michael, ed. Approach to pulmonary infections in the immunocompromised host. Futura Pub. Co., 1991.

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Bowman, Simon, John Hamburger, Elizabeth Price, and Saaeha Rauz. Sjögren’s syndrome—clinical features. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199642489.003.0127.

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Sjögren's syndrome is a chronic, immune-mediated, condition of unknown aetiology characterized by focal lymphocytic infiltration of exocrine glands associated with dry mouth and eyes. It occurs in its own right (primary Sjögren's syndrome, pSS), or as a late feature of other rheumatic diseases such as rheumatoid arthritis, systemic lupus erythematosus or scleroderma (secondary Sjögren's syndrome). There is a strong female bias. pSS typically affects women in their middle years with an estimated prevalence of 0.1–0.6%. 75% of patients have anti-Ro and/or anti-La antibodies, often with raised im
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Bowman, Simon, John Hamburger, Elizabeth Price, and Saaeha Rauz. Sjögren’s syndrome—clinical features. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199642489.003.0127_update_001.

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Sjögren’s syndrome is a chronic, immune-mediated, condition of unknown aetiology characterized by focal lymphocytic infiltration of exocrine glands associated with dry mouth and eyes. It occurs in its own right (primary Sjögren’s syndrome, pSS), or as a late feature of other rheumatic diseases such as rheumatoid arthritis, systemic lupus erythematosus or scleroderma (secondary Sjögren’s syndrome). There is a strong female bias. pSS typically affects women in their middle years with an estimated prevalence of 0.1–0.6%. 75% of patients have anti-Ro and/or anti-La antibodies, often with raised im
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Csn, Joe Correa. 53 Potent Lung Cancer Salad Recipes: Cancer-Fighting Superfoods That Will Strengthen Your Immune System. Independently Published, 2019.

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Schlesinger, Richard B., Judith T. Zelikoff, and Mitchell D. Cohen. Pulmonary Immunotoxicology. Springer, 2012.

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Schlesinger, Richard B., Judith T. Zelikoff, and Mitchell D. Cohen. Pulmonary Immunotoxicology. Springer London, Limited, 2012.

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Toner, Andrew, Mark Hamilton, and Maurizio Cecconi. Post-surgery, post-anaesthesia complications. Edited by Jonathan G. Hardman. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0047.

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Postoperative complications are common in high-risk surgical populations and are associated with poor short-term and long-term outcomes. Morbidity can be identified using prospective assessment of pathological criteria, or deviations from the ideal postoperative course requiring clinical intervention. While infections are the most prevalent complication type, morbidity affecting the heart, lungs, kidneys, or brain carry the worst prognosis. Specific pathophysiological processes drive morbidity in each organ system. In addition, dysfunction of the cardiovascular and immune systems can lead to m
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Csn, Joe Correa. 89 Organic Lung Cancer Salad and Meal Recipes: These Salads and Meals Will Strengthen Your Immune System Through Powerful Superfood Sources. Independently Published, 2019.

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Schatz, Michael. Asthma and Immunological Diseases in Pregnancy and Early Infancy (Lung Biology in Health and Disease). Informa Healthcare, 1997.

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Rx For Youth: Look and feel younger. Oxford-Hanover Press, 2003.

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Book chapters on the topic "Immune system and lung affections"

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Catterall, James R., and Edward A. Sheffield. "The Lung and the Immune System." In Autoimmune Aspects of Lung Disease. Birkhäuser Basel, 1998. http://dx.doi.org/10.1007/978-3-0348-8926-1_1.

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Kvell, Krisztian, and Judit E. Pongracz. "Immunosenescence and the Ageing Lung." In The Ageing Immune System and Health. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-43365-3_6.

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Moura, Marta Casal, and Ulrich Specks. "Lung Involvement in ANCA-Associated Vasculitis." In Rare Diseases of the Immune System. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-02239-6_10.

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Palermo, Adalgisa, Edoardo Biancalana, Emanuele Chiara, Chiara Moroni, Elisabetta Rosi, and Giacomo Emmi. "Lung Involvement in Systemic Autoimmune Disease." In Rare Diseases of the Immune System. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-60855-1_14.

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Pennisi, Marzio, Francesco Pappalardo, and Santo Motta. "Agent Based Modeling of Lung Metastasis-Immune System Competition." In Lecture Notes in Computer Science. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-03246-2_1.

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Booth, Helen, and Geoffrey J. Laurent. "Role of the Immune System in the Pathogenesis of Cryptogenic Fibrosing Alveolitis." In Autoimmune Aspects of Lung Disease. Birkhäuser Basel, 1998. http://dx.doi.org/10.1007/978-3-0348-8926-1_10.

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Karuppieh, Santhiya, Sri Renukadevi Balusamy, Sumathi Sundaravadivelu, Lakshmi Thangavelu, and Haribalan Perumalsamy. "Advanced Drug Delivery Systems Targeting the Immune System at Cellular Level in Chronic Respiratory Diseases." In Advanced Drug Delivery Strategies for Targeting Chronic Inflammatory Lung Diseases. Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-4392-7_16.

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Sagawa, Tomoya, Raga Ishikawa, Sakiko Akaji, Akiko Honda, Takayuki Kameda, and Hirohisa Takano. "Relationship Between Bio-Distribution of Environmental Particles and Induction of Biological and Immune Response in the Respiratory System." In Extracellular Fine Particles. Springer Nature Singapore, 2025. https://doi.org/10.1007/978-981-97-7067-0_11.

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Abstract Environmental particles, such as PM2.5, diesel exhaust particles, and metal nanoparticles, are known to affect the respiratory and immune systems. Although environmental particles exhibit toxicity owing to their unique physical and chemical properties, little is known about the relationship between the bio-distribution and dynamics of environmental particles and health effects. This review introduces a novel method in which Raman microscopy is combined with histological staining, such as hematoxylin–eosin staining, immunostaining, and Diff-Quik staining, to evaluate the bio-distributi
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Osborne, Erika. "Exposing the Anthropocene." In Making the Geologic Now. punctum books, 2012. https://doi.org/10.21983/p3.0014.1.08.

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In the age of the Anthropocene, human impact on a geologic scale infiltrates nearly every aspect of contemporary life. The immense breadth and depth of the changes to the planet that have been caused by this impact have affected my work and my pedagogy as an artist and educator interested in connections between culture and environment.Although I have always been interested in the Anthropocene, my fascination with its artifacts grew when I accepted a teaching position in the School of Art and Design at West Virginia University and moved to “The Mountain State”—or what West Virginia’s former gov
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Sezgin, Yasin, and Mahmut Kara. "Immunotherapy in Gastro-Esophageal Cancers." In Immunotherapy in Human Cancers. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359388.14.

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Cancers of the gastro-oesophageal system represent the fourth most common cancer type, following lung and breast cancers. Mortality rates remain high due to late diagnosis. In the context of gastrointestinal malignancies, the tumour microenvironment and immune system play a pivotal role in cancer progression and treatment response. The role of immunotherapy in the treatment of gastroesophageal cancers has become increasingly significant in recent years. Immunotherapy, which was previously employed solely in the context of metastatic gastric cancer, has recently been established as a standard t
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Conference papers on the topic "Immune system and lung affections"

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Gunay, Melike, Zeynep Orman, Tolga Ensari, Saliha Oukid, and Nadjia Benblidia. "Diagnosis of Lung Cancer Using Artificial Immune System." In 2019 Scientific Meeting on Electrical-Electronics & Biomedical Engineering and Computer Science (EBBT). IEEE, 2019. http://dx.doi.org/10.1109/ebbt.2019.8742075.

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Ayeni, Deborah, Ping-Chih Ho, Curtis Perry, Susan Kaech, and Katerina Politi. "Abstract A083: Modulation of the immune system as a strategy to treat EGFR mutant lung adenocarcinoma." In Abstracts: CRI-CIMT-EATI-AACR Inaugural International Cancer Immunotherapy Conference: Translating Science into Survival; September 16-19, 2015; New York, NY. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/2326-6074.cricimteatiaacr15-a083.

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KleinJan, Alex, Menno van Nimwegen, Bernt van den Blink, Henk C. Hoogsteden, and Rudi W. Hendriks. "Involvement Of The Immune System In Chronic Beryllium Disease Model. The Presence Of Granuloma Like Structures In The Lung." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a5713.

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Wijesooriya, Krishni, James M. Larner, Paul W. Read, et al. "629-E Randomized trial comparing conventional vs novel treatment planning technique to improve the immune system during lung SBRT." In SITC 38th Annual Meeting (SITC 2023) Abstracts Supplement 2. BMJ Publishing Group Ltd, 2023. http://dx.doi.org/10.1136/jitc-2023-sitc2023.0629-e.

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Markman, Janet L., Daiko Wakita, Timothy R. Crother, and Moshe Arditi. "Abstract 4057: Gender and the immune system in lung and liver colonization of murine melanoma in a B16 metastatic model." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-4057.

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Kurz, M., L. Rieger, P. Giansanti, B. Kuster, and F. Bassermann. "P01.05 Deciphering the function of the ubiquitin-proteasome-system in regulating the immune checkpoint protein B7-H3 (CD276) in non-small cell lung cancer." In iTOC8 – the 8th Leading International Cancer Immunotherapy Conference in Europe, 8–9 October 2021, Virtual Conference. BMJ Publishing Group Ltd, 2021. http://dx.doi.org/10.1136/jitc-2021-itoc8.9.

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Souza, Matheus Fellipe Nascimento de, Ana Paula Teixeira da Silva, Gabriela Santos Bianchin, et al. "Progressive disseminated histoplasmosis with pulmonary and central nervous system involvement: a case report." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.559.

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Context: Histoplasmosis (Histoplasma capsulatum) is a systemic disease that affects the lung and immune system1. The severity of histoplasmosis is directly related to the individual’s immune response since it is an opportunistic pathogen2. It is one of the most prevalent infections in immunocompromised patients due to the use of tumor necrosis factor-alpha (TNF-alpha) inhibitors, resulting in a mortality rate of 20%. The evolution to CNS occurs in 5-10% of patients with disseminated symptoms3. Case Report: M.G.M, a woman, 67 years, was admitted with bilateral tonicclonic seizure with focal ons
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Richardson, Janell R., Megan MacBride, Esther Andino, et al. "Abstract 2935: Defining variation within a next gen humanized immune system mouse model of human lung cancer in the context of a checkpoint inhibitor efficacy study." In Proceedings: AACR Annual Meeting 2021; April 10-15, 2021 and May 17-21, 2021; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-2935.

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Parra, Edwin Roger, Mei Jiang, Jiexin Zhang, et al. "Abstract 3633: Immunofluorescence profiling of co-expression of multiple immune checkpoints in malignant and tumor infiltrated lymphocytes in non-small cell lung carcinomas using image analysis system." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-3633.

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Boogaerts, M. A., P. Zachée, M. P. Emonds, W. Goossens, R. L. Verwilghen, and R. L. Lins. "ERYTHROCYTES(RBC) AS SUICIDAL ENDOGENOUS SCAVENGERS IN IMMUNE TRIGGERED GRANULOCYTE(PMN)MEDIATED VASCULAR DAMAGE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643162.

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PMN produced toxic oxygen radicals(TOR)have been implicated in the generation of endothelial injury in a number of clinical conditions e.g. in apheresis,hemodialysis, ARDS and atherosclerosis. RBC have shown to inhibit TOR induced damage in a number of hyper-oxic lung injury models.We surmised RBC may serve as endogenous TOR scavengers in those in vivo situations where PMN are immunologically triggered(e.g. complement-activation in hemodialysis)to produce endothelial damage.However, RBC in their role as scavengers may became more vulnerable to further oxydant stress and display a reduced life
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