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1

Dashputra, Amruta Vishwas, Nayse Jaydeep, Siddique R, Amit Date, and Quazi Shadama. "Perception and preference of health care providers regarding protective role of immunity boosters against Covid -19." Panacea Journal of Medical Sciences 13, no. 1 (2023): 103–8. http://dx.doi.org/10.18231/j.pjms.2023.022.

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Covid -19 caused by a virus to which the people with low immunity response are being affected. Immune boosters play a vital role in protecting human being from various infective organism. The immune boosters include vitamins, minerals, antioxidants, probiotics etc. Indian Government gave emphasis on improving immunity in March 2020. At That time many people started using immunity booster agents. : To study perception and preference of medical teachers about immunity booster agents against Covid -19. A questionnaire based cross sectional study was conducted among medical teachers. Questionnaire
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Massonnaud, Clément R., Jonathan Roux, Vittoria Colizza, and Pascal Crépey. "Evaluating COVID-19 Booster Vaccination Strategies in a Partially Vaccinated Population: A Modeling Study." Vaccines 10, no. 3 (2022): 479. http://dx.doi.org/10.3390/vaccines10030479.

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Background: Several countries are implementing COVID-19 booster vaccination campaigns. The objective of this study was to model the impact of different primary and booster vaccination strategies. Methods: We used a compartmental model fitted to hospital admission data in France to analyze the impact of primary and booster vaccination strategies on morbidity and mortality, assuming waning of immunity and various levels of virus transmissibility during winter. Results: Strategies prioritizing primary vaccinations were systematically more effective than strategies prioritizing boosters. Regarding
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Dangi, Tanushree, Sarah Sanchez, Min Han Lew, et al. "Pre-existing immunity modulates responses to mRNA boosters." Journal of Immunology 210, no. 1_Supplement (2023): 59.05. http://dx.doi.org/10.4049/jimmunol.210.supp.59.05.

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Abstract mRNA vaccines have shown high efficacy in preventing severe COVID-19, but breakthrough infections, emerging variants and waning antibody levels have warranted the use of boosters. Although mRNA boosters have been widely implemented, the extent to which pre-existing immunity influences the efficacy of boosters remains unclear. In a cohort of individuals primed with the mRNA-1273 or BNT162b2 vaccines, we observed that lower spike-specific antibody levels before boost were associated with higher fold-increase in spike-specific antibody levels after boost, suggesting that pre-existing ant
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Nanavaty, Dhairya P., Ankushi A. Sanghvi, Manav S. Mehta, Sarbari Gupta, and Gurusharan Dumra. "A cross-sectional study for determining the perception and preferences of immunity boosters for protection against COVID-19." International Journal of Advances in Medicine 7, no. 10 (2020): 1498. http://dx.doi.org/10.18203/2349-3933.ijam20204022.

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Background: The World Health Organisation declared the novel coronavirus (COVID-19) outbreak as a global pandemic on March 11, 2020. The consumption of vitamins, especially C, D, and zinc, hydroxychloroquine, and Arsenicum album 30 (homeopathy), has increased tremendously. However, the clinical trial showing the benefits of these agents is still underway though there have been a lot of discussion about these in print, electronic, and social media.Method: A questionnaire-based observational study was conducted. The participants were inquired about the use of any type of immunity booster by them
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*Kamlesh, S. Pathak, Santosh Jain Dr., and M. Waghmode D. "THE FORMULATION, DEVELOPMENT, AND EVALUATION OF AN IMMUNITY BOOSTER AIMED AT TO BOOST IMMUNITY DURING CANCER THERAPY." World Journal of Pharmaceutical Science and Research 3, no. 4 (2024): 100–112. https://doi.org/10.5281/zenodo.13150620.

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In recent years, there has been a noticeable shift towards herbal formulations over synthetic ones. While there are numerous herbal immunity boosters available in the market, there is a lack of options specifically tailored for cancer patients. To address this issue and mitigate the side effects of cancer therapy, it is imperative to develop an immunity booster using a combination of various herbal ingredients. Such as Ashwagandha, Cinnamon, Ginger, Guduchi, Coffee. The combination of these herbal ingredients produce an effect to minimize the side effect of cancer therapy. Use as WBC enhancer,
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Kamlesh, S. Pathak Santosh Jain D. M. Waghmode. "The Formulation, Development, And Evaluation Of An Immunity Booster Aimed At To Boost Immunity During Cancer Therapy." International Journal in Pharmaceutical Sciences 2, no. 7 (2024): 1570–80. https://doi.org/10.5281/zenodo.12790514.

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In recent years, there has been a noticeable shift towards herbal formulations over synthetic ones. While there are numerous herbal immunity boosters available in the market, there is a lack of options specifically tailored for cancer patients. To address this issue and mitigate the side effects of cancer therapy, it is imperative to develop an immunity booster using a combination of various herbal ingredients. Such as Ashwagandha, Cinnamon, Ginger, Guduchi, Coffee. The combination of these herbal ingredients produce an effect to minimize the side effect of cancer therapy. Use as WBC enhancer,
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7

Pitisuttithum, Punnee, Chukiat Sirivichayakul, Jittima Dhitavat, Arom Pitisuthitham, Souad Mansouri, and Hong Thai Pham. "Pertussis Immunity 5 Years After Booster Vaccination With Recombinant Pertussis Vaccines." JAMA Network Open 7, no. 12 (2024): e2449182. https://doi.org/10.1001/jamanetworkopen.2024.49182.

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8

Livieratos, Achilleas, Lars Erik Schiro, Charalambos Gogos, and Karolina Akinosoglou. "Durability of Adaptive Immunity in Immunocompetent and Immunocompromised Patients Across Different Respiratory Viruses: RSV, Influenza, and SARS-CoV-2." Vaccines 12, no. 12 (2024): 1444. https://doi.org/10.3390/vaccines12121444.

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Background/Objectives. Research on respiratory virus immunity duration post-vaccination reveals variable outcomes. This study performed a literature review to assess the efficacy and longevity of immune protection post-vaccination against SARS-CoV-2, influenza, and respiratory syncytial virus (RSV), with a focus on immunocompromised populations. Specific objectives included examining humoral and cellular immune responses and exploring the impact of booster doses and hybrid immunity on extending protection. Methods. A literature review was conducted focusing on studies published from January 20
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9

Violán, Concepció, Bibiana Quirant-Sánchez, Maria Palau-Antoja, et al. "Immune Durability and Breakthrough Infections 15 Months After SARS-CoV-2 Boosters in People over 65: The IMMERSION Study." Vaccines 13, no. 7 (2025): 738. https://doi.org/10.3390/vaccines13070738.

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Background: SARS-CoV-2 booster vaccination remains essential to prevent severe COVID-19, particularly in vulnerable populations such as older adults. This study evaluated the durability and dynamics of immune responses following booster vaccination(s) in >65-year-old individuals and examined their association with protection against new infections. Methods: Immune responses were evaluated at 3, 9, and 15 months post-booster, measuring SARS-CoV-2-specific IgG antibodies against spike [IgG(S)] and nucleocapsid [IgG(N)] proteins, neutralizing activity against the Omicron BA.2 variant, and cell
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Kannamreddy, Vikram, M. Jeeva, Girija Prasad Patnaik, et al. "IMMUNITY BOOSTERS TO COMBAT COVID-19 PANDEMIC." Journal of Experimental Biology and Agricultural Sciences 8, Spl-1-SARS-CoV-2 (2020): S119—S125. http://dx.doi.org/10.18006/2020.8(spl-1-sars-cov-2).s119.s125.

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Corona virus disease 2019 (COVID-19) pandemic is caused by SARS-CoV2 (Severe Acute Respiratory Syndrome Coronavirus-2). It primarily targets lung epithelial cells of human respiratory system. The original strain of coronavirus was first identified at the end of December 2019 and emerged during an outbreak in Wuhan, China. The SARS-CoV-2 infection is mostly seen in the people with weak immune system. There are different ex-situ approaches to prevent the infection of corona virus viz., use of masks, sanitizing body and surfaces and maintaining social distance. But apart from them, in-situ preven
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Chahal, Dr Ravneet Kaur. "Immunity Boosters In Ayurveda & Daily Foods." International Journal of Medical Science 7, no. 9 (2020): 1–6. http://dx.doi.org/10.14445/23939117/ijms-v7i9p101.

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Yadav, Rekha, Mamta Singh, Raveena Raveena, Partibha Partibha, and Neha Bajal. "Intake of immunity boosters by Covid -19 patients of Bikaner city." International Journal of Environment, Agriculture and Biotechnology 9, no. 2 (2024): 010–17. http://dx.doi.org/10.22161/ijeab.92.2.

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Corona virus disease 2019 (COVID-19) is an acute and contagious disease characterized by pneumonia and acute respiratory distress syndrome, which is caused by a novel corona virus (2019-nCoV). Three hundred post Covid-19 adult (19-39 years) patients were selected for present study comprising 150 males and 150 females. Subjects were selected after procuring the list of patients from Prince Bijay Singh Memorial and Shri Ram Hospital, Bikaner (Rajasthan) by purposive/ convenient random sampling on the basis of their willingness to cooperate during the study. The study had been carried out from Ja
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13

Hanson, James F., Sarah C. Taft, and Alison A. Weiss. "Neutralizing Antibodies and Persistence of Immunity following Anthrax Vaccination." Clinical and Vaccine Immunology 13, no. 2 (2006): 208–13. http://dx.doi.org/10.1128/cvi.13.2.208-213.2006.

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ABSTRACT Anthrax toxin consists of protective antigen (PA) and two toxic components, lethal factor (LF) and edema factor (EF). PA binds to mammalian cellular receptors and delivers the toxic components to the cytoplasm. PA is the primary antigenic component of the current anthrax vaccine. Immunity is due to the generation of antibodies that prevent the PA-mediated internalization of LF and EF. In this study, we characterized sera obtained from vaccinated military personnel. Anthrax vaccine is administered in a series of six injections at 0, 2, and 4 weeks and 6, 12, and 18 months, followed by
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14

Tang, Jinyi, Arka Chaudhuri, Panke Qu, et al. "Respiratory mucosal immunity against SARS-CoV-2 after vaccination and infection." Journal of Immunology 212, no. 1_Supplement (2024): 1559_5071. http://dx.doi.org/10.4049/jimmunol.212.supp.1559.5071.

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Abstract The current COVID-19 mRNA vaccine is effective in systemic immune memory but lacks in generating mucosal anti-SARS-CoV-2 immunity. While prior SARS-CoV-2 infection establishes respiratory immunity, its strain-specific nature and limited duration pose challenges for sustained protection. Recent research has shown that hybrid immunity, a combination of vaccination and infection, results in a more robust, durable, and broadly reactive immune response in circulation compared to vaccination or infection alone. However, the characteristics and protective mechanisms of hybrid immunity in the
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Zhang, Zhiren, Qiaren He, Wei Zhao, et al. "A Heterologous V-01 or Variant-Matched Bivalent V-01D-351 Booster following Primary Series of Inactivated Vaccine Enhances the Neutralizing Capacity against SARS-CoV-2 Delta and Omicron Strains." Journal of Clinical Medicine 11, no. 14 (2022): 4164. http://dx.doi.org/10.3390/jcm11144164.

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Immune escape of emerging SARS-CoV-2 variants of concern (VOCs) and waning immunity over time following the primary series suggest the importance and necessity of booster shot of COVID-19 vaccines. With the aim to preliminarily evaluate the potential of heterologous boosting, we conducted two pilot studies to evaluate the safety and immunogenicity of the V-01 or a bivalent V-01D-351 (targeting Delta and Beta strain) booster after 5–7 months of the primary series of inactivated COVID-9 vaccine (ICV). A total of 77 participants were enrolled, with 20 participants in the V-01D-351 booster study,
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16

Shrivastava, Renuraj. "Immunity boosters: Solutions from nature – Herbs and spices." Journal of Renal Nutrition and Metabolism 6, no. 2 (2020): 35. http://dx.doi.org/10.4103/jrnm.jrnm_20_20.

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17

Muller, Gregory, Christopher B. Gage, Jonathan R. Powell, et al. "Emergency Medical Services Clinicians and COVID-19 Booster Behavior—A Cross-Sectional National Evaluation." Vaccines 13, no. 5 (2025): 457. https://doi.org/10.3390/vaccines13050457.

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Background/Objectives: Emergency Medical Services (EMS) clinicians in the US have high COVID-19 vaccine hesitancy rates and often do not receive primary vaccinations or subsequent boosters. The extent of booster attrition following initial vaccination and first booster dose in EMS clinicians is unknown. Our objective was to evaluate the prevalence and drivers of COVID-19 booster attrition in EMS clinicians. We hypothesized that booster attrition is common among EMS clinicians and associated with various EMS characteristics. Methods: This study was a cross-sectional analysis of nationally certi
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18

Sharma, Rajesh, Mansi Rajput, and Priyanka Sharma. "COVID Patient Counselling: An Imperative Exigency." International Journal of Health Sciences and Research 11, no. 11 (2021): 87–101. http://dx.doi.org/10.52403/ijhsr.20211110.

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The research include methodology consisted of conducting the Survey based research with different awareness campaign. Special Survey Campaign of which quantitative survey was a part involved conscientious background research, discussion, and survey formation. The motive of the campaign was to collect information about the troubles, help, or advice people needed through Google forms. According to our survey, 61.29% of people have faced the core symptoms of the virus, out of the total population 62.9% people have been taking immunity boosters including Zinc and Vitamin C. The people hit by the D
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Núñez-Franz, Loreto, Muriel Ramírez-Santana, Paola Rubilar, et al. "Seroprevalence of Natural and Acquired Immunity against the SARS-CoV-2 Virus in a Population Cohort from Two Chilean Cities, 2020–2022." Viruses 15, no. 1 (2023): 201. http://dx.doi.org/10.3390/v15010201.

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Background: Chile has achieved the highest coverage for vaccines against the SARS-CoV-2 virus worldwide. Objective: To assess the progression of immunity (natural and acquired by vaccine) in a cohort from two Chilean cities. Methods: Individuals (n = 386) who participated in three phases of population-based serial prevalence studies were included (2020–2021 and 2022). Presence of SARS-CoV-2 antibodies was measured in serum. Data including time of vaccination and type of vaccine received were analysed with descriptive statistics. Results: Seroprevalence was 3.6% in the first round and increased
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20

Sree lakshmi S B and Geetha R V. "Knowledge and Awareness about Natural Immune Booster Among General Public." International Journal of Research in Pharmaceutical Sciences 11, SPL3 (2020): 1156–64. http://dx.doi.org/10.26452/ijrps.v11ispl3.3358.

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The immune system plays a vital role in protecting the body against diseases, fighting against foreign bodies and does a remarkable job in defending against microorganism and distinguishing bodies' own health issues and protecting them from infectious agents. Natural immune boosters are the product, which helps in boosting the immune system. Even some pharmaceutical preparation includes medicinal plants as they are compound extract again is a variety of diseases. Ayurvedic theory states that balance between the humours of the body that is “vayu, pitta and kaffa” leads to healthy living. The bo
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Chia, Travis Ren Teen, Barnaby Edward Young, and Po Ying Chia. "The Omicron-transformer: Rise of the subvariants in the age of vaccines." Annals of the Academy of Medicine, Singapore 51, no. 11 (2022): 712–29. http://dx.doi.org/10.47102/annals-acadmedsg.2022294.

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Introduction: Omicron is the latest SARS-CoV-2 variant of concern, the pathogen that causes COVID-19. Since its emergence in late 2021, Omicron has displaced other circulating variants and caused successive waves of infection worldwide throughout 2022. Omicron is characterised by the rapid emergence of many subvariants and high rates of infection in people with vaccine- and/or infection-induced immunity. This review article will consolidate current knowledge regarding Omicron subvariants, the role of boosters, and future vaccine development. Method: This narrative review is based on a literatu
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de León, Ugo Avila-Ponce, Angel G. C. Pérez, and Eric Avila-Vales. "Modeling the SARS-CoV-2 sublineages XBB and BQ.1 in Mexico, considering multiple vaccinations, booster dose, waning immunity and cross-immunity." Electronic Research Archive 32, no. 2 (2024): 1082–125. http://dx.doi.org/10.3934/era.2024053.

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<abstract><p>In a population with ongoing vaccinations, the trajectory of a pandemic is determined by how the virus spreads in the unvaccinated, vaccinated without boosters, and vaccinated with boosters, which will exhibit distinct transmission dynamics based on different levels of natural and vaccine-induced immunity. We found that enhancing the use of face masks in a partially vaccinated population is associated with a reduction of new infections, hospitalizations, and deaths. We highly recommend the use of a face mask with at least a 50% efficiency, such as improved cloth and su
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Thukral, Prachi, Ruchita Chowdhury, Vishal Chaudhary, Akash Gautam, and Pankaj Prasad. "Study of Public Awareness about Immunity and Immunity Boosters Against Covid-19 in India." ECS Transactions 107, no. 1 (2022): 11609–22. http://dx.doi.org/10.1149/10701.11609ecst.

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Since December 2019, the world has been under emergency due to novel coronavirus disease (Covid-19). Due to a lack of powerful preventative strategies (such as vaccinations) and pharmaceutical treatments, various preventive techniques have been implemented worldwide. Boosting the immune system is one of the most popular tools which has gained worldwide attention. However, the general public's impression is tainted by a lack of understanding of immune-boosting strategies and timetables. We carried out questionnaire-based research in India to assess people's actual knowledge of immunity and immu
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Honfi, Dániel, Nikolett Gémes, Enikő Szabó, et al. "Comparison of Homologous and Heterologous Booster SARS-CoV-2 Vaccination in Autoimmune Rheumatic and Musculoskeletal Patients." International Journal of Molecular Sciences 23, no. 19 (2022): 11411. http://dx.doi.org/10.3390/ijms231911411.

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Vaccination against SARS-CoV-2 to prevent COVID-19 is highly recommended for immunocompromised patients with autoimmune rheumatic and musculoskeletal diseases (aiRMDs). Little is known about the effect of booster vaccination or infection followed by previously completed two-dose vaccination in aiRMDs. We determined neutralizing anti-SARS-CoV-2 antibody levels and applied flow cytometric immunophenotyping to quantify the SARS-CoV-2 reactive B- and T-cell mediated immunity in aiRMDs receiving homologous or heterologous boosters or acquired infection following vaccination. Patients receiving a he
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Wee, Liang En, Enoch Xue Heng Loy, Jue Tao Lim, et al. "Real-World Effectiveness of Boosting Against Omicron Hospitalization in Older Adults, Stratified by Frailty." Vaccines 13, no. 6 (2025): 565. https://doi.org/10.3390/vaccines13060565.

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Background/Objectives: Older adults with frailty are at-risk of worse outcomes following respiratory-viral-infections such as COVID-19. Data on effectiveness of vaccination/boosting in frail older adults during Omicron is lacking. Methods: National healthcare-claims data and COVID-19 registries were utilized to enroll a cohort of older Singaporeans (≥60 years) as of 1 January 2022, divided into low/intermediate/high-risk for frailty; matching weights were utilized to adjust for sociodemographic differences/vaccination uptake at enrolment across frailty categories. Competing-risk-regression (Fi
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LUZ, P. M., C. T. CODEÇO, G. L. WERNECK, and C. J. STRUCHINER. "A modelling analysis of pertussis transmission and vaccination in Rio de Janeiro, Brazil." Epidemiology and Infection 134, no. 4 (2005): 850–62. http://dx.doi.org/10.1017/s095026880500539x.

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Pertussis is an infectious respiratory disease for which mass vaccination is an effective preventive strategy. In many developed countries, where high vaccination coverage has been maintained for approximately 50 years, re-emergence of the disease has been observed in all age groups. In the municipality of Rio de Janeiro (RJ), where vaccination started in the 1980s, surveillance data show no sign of disease re-emergence. We developed a mathematical model that incorporates the major demographic aspects of a large urban centre in a developing nation, in addition to the most important epidemiolog
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He, Qiaren, Shiyu Sun, Xi Chen, et al. "The Bivalent COVID-19 Booster Immunization after Three Doses of Inactivated Vaccine Augments the Neutralizing Antibody Response against Circulating Omicron Sublineages." Journal of Clinical Medicine 12, no. 1 (2022): 146. http://dx.doi.org/10.3390/jcm12010146.

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A fourth dose of a COVID-19 vaccine has been recommended by a number of authorities due to waning immunity over time and the emergence of immune-escaping variants. Here, we evaluated the safety and immunogenicity of the bivalent BV-01-B5 or V-01D-351 or the prototype V-01 for heterologous boosting in three-dose inactivated COVID-19 vaccine (ICV) recipients, in comparison with ICV homologous boosting. One pilot study (NCT05583357) included 20 participants randomized at 1:1, either receiving V-01D-351 or CoronaVac. The other one (NCT05585567) recruited 36 participants randomized at 2:1, either r
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Kusunoki, Hiroshi. "Current Status and Significance of Additional Vaccination with COVID-19 Vaccine in Japan—Considerations from Antibody Levels from Hybrid Immunity and Public Perceptions." Vaccines 12, no. 12 (2024): 1413. https://doi.org/10.3390/vaccines12121413.

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This report examines the evolving role of coronavirus disease 2019 (COVID-19) vaccination in Japan, especially in light of the reduced public concern following the reclassification of COVID-19 as a Category 5 infectious disease in May 2023. With over half the population estimated to have hybrid immunity from prior infections and vaccinations, this report evaluated the necessity and frequency of additional booster doses. Despite strong recommendations from Japanese medical societies to continue vaccination, public skepticism remains owing to financial burdens, adverse reactions, and the perceiv
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Hurst, Jacklyn R., Maedeh Naghibosadat, Patrick Budowski, et al. "Comparison of a SARS-CoV-2 mRNA booster immunization containing additional antigens to a spike-based mRNA vaccine against Omicron BA.5 infection in hACE2 mice." PLOS ONE 19, no. 12 (2024): e0314061. https://doi.org/10.1371/journal.pone.0314061.

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The emergence of SARS-CoV-2 variants presents challenges to vaccine effectiveness, underlining the necessity for next-generation vaccines with multiple antigens beyond the spike protein. Here, we investigated a multiantigenic booster containing spike and a chimeric construct composed of nucleoprotein (N) and membrane (M) proteins, comparing its efficacy to a spike-only booster against Omicron BA.5 in K18-hACE2 mice. Initially, mice were primed and boosted with Beta (B.1.351) spike-only mRNA, showing strong spike-specific T cell responses and neutralizing antibodies, albeit with limited cross-n
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Dr., Ravneet Kaur, Shashidhar Kumar Dr., Sujith N. V. Dr., and Honey SR Prasad Dr. "Role of Ayurveda in COVID-19: Pros & Cons." International Journal Of Medical Science And Clinical Research Studies 02, no. 11 (2022): 1253–56. https://doi.org/10.5281/zenodo.7316325.

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Ayurveda is a great science. If it is followed properly gives miraculous benefits. These days COVID -19 is an emerging disease as a pandemic with various signs and symptoms. A lot of Ayurvedic whether herbal or herbo-mineral drugs are used for the treatment as per the protocols suggested. Among all these opportunities in front of doctors and vaidyas Ayurveda which was emanated since times from our ancient sages is perpetuating more than before as to serve the humanity.  There are a lot of preparations used these days for COVID-19 by the Ayurvedic physicians. Sometimes common people use th
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Barreiro, Pablo, and Jesús San Román. "Vulnerability to SARS-CoV-2 infection and disease: ripping the curl after the storm." Revista Española de Quimioterapia 35, Suppl3 (2022): 2–5. http://dx.doi.org/10.37201/req/s03.01.2022.

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SARS-CoV-2 infection now seems to have entered the announced endemic phase. The population’s immunity is increasingly more robust, thanks to successive vaccination and booster campaigns, and the almost inevitable exposure and re-exposure to the virus itself, which has truly served as a natural immunizing mechanism. On the other hand, the genetic drift of the virus is leading it to become another catarrhal agent, as are the other endemic human coronaviruses. However, it should not be lost sight of that there are still segments of the population with susceptibility to severe COVID, who will be c
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Clémenceau, Béatrice, Amandine Le Bourgeois, Thierry Guillaume, et al. "Strong SARS-CoV-2 T-Cell Responses after One or Two COVID-19 Vaccine Boosters in Allogeneic Hematopoietic Stem Cell Recipients." Cells 11, no. 19 (2022): 3010. http://dx.doi.org/10.3390/cells11193010.

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A full exploration of immune responses is deserved after anti-SARS-CoV-2 vaccination and boosters, especially in the context of allogeneic hematopoietic stem cell transplantation (allo-HSCT). Although several reports indicate successful humoral responses in such patients, the literature is scarce on cellular specific immunity. Here, both B- (antibodies) and T-cell responses were explored after one (V3 n = 40) or two (V4 n = 12) BNT162b2 mRNA vaccine boosters in 52 allo-HSCT recipients at a median of 755 days post-transplant (<1 year n = 9). Results were compared with those of 12 controls wh
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V, Mallya Suma, and Satish B N. "Evident experimental data of Habenaria longicorniculata J Graham on Cell mediated immunity - Promising source of Herbal immunomodulator." International Journal of Ayurvedic Medicine 13, no. 2 (2022): 508–10. http://dx.doi.org/10.47552/ijam.v13i2.2718.

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Habenaria longicorniculata J. Graham from family Orchidaceae, are tuberous herbs, widely used by traditional physicians in the treatment of malignancy as a rejuvenator, immune boosters. Protocol designed to evaluate its In-vivo Immunomodulatory activity by cell mediated immunity. Materials and methods: Tubers were collected, cleaned, used for further study. In-vivo Immunomodulatory activity on rats for Assessment of immunity by Cell mediated Immunity, conducted as per the standard protocol. Results: Analysis of the results of the study indicates that the test drug Tubers possesses very good im
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Alhit, Hazim Abdul Rahman. "COVID Booster Shot and the Third Dose." Journal of Medical Research and Surgery 2, no. 6 (2021): 1. http://dx.doi.org/10.52916/jmrs204065.

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The protection provided by the original shot(s) has begun to decrease over time, then a Coronavirus Disease (COVID) booster shot is given. Moreover, the immunity from the initial dose(s) naturally starts to wane, and you would get a booster. Accordingly, the booster is designed in order to maintain the people’s level of immunity for longer [1]. There is evidence that the effect of the vaccine wanes over time, so the officials recommended booster shots for everyone who is eighteen and older [2]. Therefore, the medics instructed the third dose for individuals who are immuno-compromised. The thir
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Alhit, Hazim Abdul Rahman. "COVID Booster Shot and the Third Dose." Journal of Medical Research and Surgery 2, no. 6 (2021): 1. http://dx.doi.org/10.52916/jmrs214065.

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The protection provided by the original shot(s) has begun to decrease over time, then a Coronavirus Disease (COVID) booster shot is given. Moreover, the immunity from the initial dose(s) naturally starts to wane, and you would get a booster. Accordingly, the booster is designed in order to maintain the people’s level of immunity for longer [1]. There is evidence that the effect of the vaccine wanes over time, so the officials recommended booster shots for everyone who is eighteen and older [2]. Therefore, the medics instructed the third dose for individuals who are immuno-compromised. The thir
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Jaggaiahgari, Shashidhar, Apoorva Munigela, Sasikala Mitnala, Deepika Gujjarlapudi, Venu Simhadri, and Nageshwar Reddy D. "Heterologous Booster Dose with CORBEVAX Following Primary Vaccination with COVISHIELD Enhances Protection against SARS-CoV-2." Vaccines 10, no. 12 (2022): 2146. http://dx.doi.org/10.3390/vaccines10122146.

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Despite effective vaccination programs, waning immunity in the vaccinated populations and the emergence of variants of concern posed a risk of breakthrough infections. A booster dose was demonstrated to provide substantially increased protection against symptomatic disease and hospitalization. We aimed to evaluate immune memory and the efficacy of reducing the rate of SARS-CoV-2 infection post heterologous booster with CORBEVAX after primary vaccination with two doses of COVISHIELD. SARS-CoV-2 S1/S2 spike IgG and RBD-specific antibody responses were elicited with both booster vaccines, with a
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Santi, Theresia, Ari Prayitno, Zakiudin Munasir, et al. "Evaluation of anti-diphtheria toxoid antibody persistence in school-age children in Jakarta, Indonesia." Paediatrica Indonesiana 64, no. 5 (2024): 447–53. http://dx.doi.org/10.14238/pi64.5.2024.447-53.

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Background Diphtheria can be effectively prevented by adequate immunization. A combined vaccine against diphtheria toxoid, pertussis, and tetanus toxoid (DPT) is currently used in routine pediatric immunizations. Outbreaks of diphtheria could emerge in Indonesia as a consequence of declining routine vaccination during the COVID-19 pandemic. Objective To analyze the impact of the first (administered at 18-24 months of age ) and second diphtheria boosters (administered at 5-7 years of age ) in retaining protective levels of anti-diphtheria toxoid antibodies. We also investigated for relevant fac
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38

Pérez-Then, Eddy, Carolina Lucas, Valter Silva Monteiro, et al. "Neutralizing antibodies against the SARS-CoV-2 Delta and Omicron variants following heterologous CoronaVac plus BNT162b2 booster vaccination." Nature Medicine 28, no. 3 (2022): 481–85. http://dx.doi.org/10.1038/s41591-022-01705-6.

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AbstractThe recent emergence of the SARS-CoV-2 Omicron variant is raising concerns because of its increased transmissibility and its numerous spike mutations, which have the potential to evade neutralizing antibodies elicited by COVID-19 vaccines. Here we evaluated the effects of a heterologous BNT162b2 mRNA vaccine booster on the humoral immunity of participants who had received a two-dose regimen of CoronaVac, an inactivated vaccine used globally. We found that a heterologous CoronaVac prime vaccination of two doses followed by a BNT162b2 booster induces elevated virus-specific antibody leve
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Rzymski, Piotr, Carlos A. Camargo, Andrzej Fal, et al. "COVID-19 Vaccine Boosters: The Good, the Bad, and the Ugly." Vaccines 9, no. 11 (2021): 1299. http://dx.doi.org/10.3390/vaccines9111299.

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Pursuing vaccinations against COVID-19 brings hope to limit the spread of SARS-CoV-2 and remains the most rational decision under pandemic conditions. However, it does not come without challenges, including temporary shortages in vaccine doses, significant vaccine inequity, and questions regarding the durability of vaccine-induced immunity that remain unanswered. Moreover, SARS-CoV-2 has undergone evolution with the emergence of its novel variants, characterized by enhanced transmissibility and ability to at least partially evade neutralizing antibodies. At the same time, serum antibody levels
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Lastuti, Nunuk Dyah Retno, Fedik Abdul Rantam, Poedji Hastutiek, and Dony Chrismanto. "Toll-Like Receptors (TLRs) Play Role in Adaptive Immunity in Rabbits Immunized by Sarcoptes scabiei Proteins." KnE Life Sciences 3, no. 6 (2017): 1. http://dx.doi.org/10.18502/kls.v3i6.1100.

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Sarcoptic mange is one of the most economically important diseases in goats in Indonesia, and increasing number of cases of treatment failure is being reported because of drug resistance. Nowadays, it is considered as an emerging/re-emerging parasitic disease that threatens human and animal health globally. Toll-Like Receptors (TLR) is a receptor which plays role in innate immunity due to microbial infection. TLR-5 is a receptor that can recognize ligand produced by bacterial component, and TLR-7 is involved in the recognition of ligand that similar to ssRNA virus. This research aims are to de
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Faraz, Ali, Malik Hina, Ali Atif, et al. "Knowledge, acceptance, motivators and barriers of booster dose of COVID-19 vaccination among dental patients: A cross-sectional study." Medicine 102, no. 45 (2023): e35747. http://dx.doi.org/10.1097/md.0000000000035747.

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Given the lingering threat of COVID infection, questions are being raised if coronavirus disease 2019 (COVID-19) vaccine needs annual or regular boosters to maintain high levels of immunity against both the original virus and variants. This study was designed to evaluate the knowledge, acceptance, motivators and barriers of the booster dose of COVID-19 vaccine among the dental patients of District Lucknow, India. A total of 297 respondents were selected by a convenience sampling method in this cross-sectional study from various dental clinics. An anonymous, self-administered, closed-ended ques
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Lapuente, Dennis, Vera Viherlehto, Jana Fuchs, et al. "Adenoviral vector vaccines are effective mucosal booster modalities to elevate systemic and establish mucosal immunity against SARS-CoV-2." Journal of Immunology 210, no. 1_Supplement (2023): 253.01. http://dx.doi.org/10.4049/jimmunol.210.supp.253.01.

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Abstract Licensed SARS-CoV-2 vaccines induce robust systemic immune responses, but mucosal immunity in the respiratory tract in form of secretory immunoglobulin A (IgA) or tissue-resident memory T cells (TRM) is not established. Inducing such front-line immunity by mucosal boosting might reduce the individual risk of breakthrough infections and thereby likely mitigate infection dynamics on population level as well. The following project evaluates preclinical and licensed adenoviral vector (Ad) platforms as mucosal SARS-CoV-2 boosters. We show that nasal instillation of Ad5- and Ad19a-Spike fol
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Mack, Philip C., Chih-Yuan Hsu, Ananda M. Rodilla, et al. "Time-Dependent Effects of Clinical Interventions on SARS-CoV-2 Immunity in Patients with Lung Cancer." Vaccines 12, no. 7 (2024): 713. http://dx.doi.org/10.3390/vaccines12070713.

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In patients with lung cancer (LC), understanding factors that impact the dynamics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) anti-spike antibody (SAb) titers over time is critical, but challenging, due to evolving treatments, infections, vaccinations, and health status. The objective was to develop a time-dependent regression model elucidating individual contributions of factors influencing SAb levels in LC patients using a prospective, longitudinal, multi-institutional cohort study initiated in January 2021. The study evaluated 296 LC patients—median age 69; 55% female; 5
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Freitas, Angela Carvalho, Valdir Okano, and Júlio Cesar Rodrigues Pereira. "Pertussis booster vaccine for adolescents and young adults in São Paulo, Brazil." Revista de Saúde Pública 45, no. 6 (2011): 1162–71. http://dx.doi.org/10.1590/s0034-89102011000600008.

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OBJECTIVE: To develop a model to assess different strategies of pertussis booster vaccination in the city of São Paulo. METHODS: A dynamic stationary age-dependent compartmental model with waning immunity was developed. The "Who Acquires Infection from Whom" matrix was used to modeling age-dependent transmission rates. There were tested different strategies including vaccine boosters to the current vaccination schedule and three of them were reported: (i) 35% coverage at age 12, or (ii) 70% coverage at age 12, and (iii) 35% coverage at age 12 and 70% coverage at age 20 at the same time. RESULT
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Fukushima, Shinji, Takashi Nakano, Minetaro Arita, Hiroyuki Shimizu, and Atsuo Hamada. "Long-Term Persistence of Anti-Poliovirus Antibody Titers After Two-Dose Booster Immunization with Conventional Inactivated Poliovirus Vaccine Among Japanese Adults: 10-Year Observational Study." Vaccines 13, no. 5 (2025): 447. https://doi.org/10.3390/vaccines13050447.

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Background/Objectives: Most Japanese adults received two doses of the oral polio vaccine (OPV) during childhood as part of the national immunization program. However, these two doses are considered suboptimal by global standards. The long-term persistence of anti-poliovirus antibodies after booster doses with the conventional inactivated poliovirus vaccine (cIPV) in Japanese adults remains unclear. This study was performed to evaluate long-term immunogenicity over a 10-year period following two cIPV booster vaccinations. Methods: Ten out of sixty-one adult participants in a short-term study we
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Singh, Namita Ashish, Pradeep Kumar, Jyoti, and Naresh Kumar. "Spices and herbs: Potential antiviral preventives and immunity boosters during COVID ‐19." Phytotherapy Research 35, no. 5 (2021): 2745–57. http://dx.doi.org/10.1002/ptr.7019.

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Minocha, Neha, Bharat Malik, Nancy Sharma, and Ishika a. "ROLE OF HEALTH, HYGIENE AND IMMUNITY BOOSTERS TO COMBAT CORONAVIRUS- A REVIEW." International Journal of Advanced Research 8, no. 5 (2020): 51–59. http://dx.doi.org/10.21474/ijar01/10907.

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Tawshikar Kulkarni, Dr Bhairav B., and Dr Shrikant G. Deshmukh. "A REVIEW ON ROLE OF AYURVEDA FOR IMMUNITY BOOSTERS AGAINST COVID 19." Journal of Bio Innovation 9, no. 5(b) (2020): 29–33. http://dx.doi.org/10.46344/jbino.2020.v09i5b.07.

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Raj, Seema, Nidhi Bansal, Arun Kaushik, et al. "IMMUNITY BOOSTERS AT ALIMENTARY AND PHYSICAL LEVELS IN RELEVANCE TO COVID-19." International Journal of Technical Research & Science Special, June (2021): 119–30. http://dx.doi.org/10.30780/specialissue-icaaset021/021.

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Burckhardt, Rachel M., John J. Dennehy, Leo L. M. Poon, Linda J. Saif, and Lynn W. Enquist. "Are COVID-19 Vaccine Boosters Needed? The Science behind Boosters." Journal of Virology 96, no. 3 (2022). http://dx.doi.org/10.1128/jvi.01973-21.

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Waning vaccine-induced immunity coupled with the emergence of SARS-CoV-2 variants has led to increases in breakthrough infections, prompting consideration for vaccine booster doses. Boosters have been reported to be safe and increase SARS-CoV-2-specific neutralizing antibody levels, but how these doses impact the trajectory of the global pandemic and herd immunity is unknown.
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