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Journal articles on the topic 'Immunity decoders'

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1

Juliy, Boiko, Pyatin Ilya, Eromenko Oleksander, and Stepanov Mykhailo. "Method of the adaptive decoding of self-orthogonal codes in telecommunication." Indonesian Journal of Electrical Engineering and Computer Science (IJEECS) 19, no. 3 (2020): 1287–96. https://doi.org/10.11591/ijeecs.v19.i3.pp1287-1296.

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The methodology description of the adaptive multi-threshold decoding of self-orthogonal codes in the telecommunication channels of information transfer is shown in this paper. The method of multi-threshold decoder modification is described on the basis of adaptive filtration algorithms. Principles of adaptive algorithms application provide for necessary data transmission validity in the case of the multi-threshold decoding are explored. The graphic charts of multi-threshold decoders noise immunity of self-orthogonal block and convolutional codes are presented. It is determined the coding gain
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2

Boiko, Juliy, Ilya Pyatin, Oleksander Eromenko, and Mykhailo Stepanov. "Method of the adaptive decoding of self-orthogonal codes in telecommunication." Indonesian Journal of Electrical Engineering and Computer Science 19, no. 3 (2020): 1287. http://dx.doi.org/10.11591/ijeecs.v19.i3.pp1287-1296.

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<p>The methodology description of the adaptive multi-threshold decoding of self-orthogonal codes in the telecommunication channels of information transfer is shown in this paper. The method of multi-threshold decoder modification is described on the basis of adaptive filtration algorithms. Principles of adaptive algorithms application provide for necessary data transmission validity in the case of the multi-threshold decoding are explored. The graphic charts of multi-threshold decoders noise immunity of self-orthogonal block and convolutional codes are presented. It is determined the cod
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3

Wen, L., Z. Li, and Y. Li. "High-performance dynamic circuit techniques with improved noise immunity for address decoders." IET Circuits, Devices & Systems 6, no. 6 (2012): 457–64. http://dx.doi.org/10.1049/iet-cds.2012.0002.

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4

Fadhil, S. Hasan, F. Mosleh Mahmood, and H. Abdulhameed Aya. "FPGA implementation of LDPC soft-decision decoders based DCSK for spread spectrum applications." International Journal of Electrical and Computer Engineering (IJECE) 11, no. 6 (2021): 4794–809. https://doi.org/10.11591/ijece.v11i6.pp4794-4809.

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Spread spectrum (SS) communications have attracted interest because of their channel attenuation immunity and low intercept potential. Apart from some extra features such as basic transceiver structures, chaotic communication would be the analog alternative to digital SS systems. Differential chaos shift keying (DCSK) systems, non-periodic and random characteristics among chaos carriers as well as their interaction with soft data are designed based on low-density parity-check (LDPC) codes in this brief. Because of simple structure, and glorious ability to correct errors. Using the Xilinx kinte
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Hasan, Fadhil S., Mahmood F. Mosleh, and Aya H. Abdulhameed. "FPGA implementation of LDPC soft-decision decoders based DCSK for spread spectrum applications." International Journal of Electrical and Computer Engineering (IJECE) 11, no. 6 (2021): 4794. http://dx.doi.org/10.11591/ijece.v11i6.pp4794-4809.

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<span lang="EN-US">Spread spectrum (SS) communications have attracted interest because of their channel attenuation immunity and low intercept potential. Apart from some extra features such as basic transceiver structures, chaotic communication would be the analog alternative to digital SS systems. Differential chaos shift keying (DCSK) systems, non-periodic and random characteristics among chaos carriers as well as their interaction with soft data are designed based on low-density parity-check (LDPC) codes in this brief. Because of simple structure, and glorious ability to <span>c
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6

Karthikeyan, P., R. Saravanan, and N. Saravanan. "Power Optimization in Domino Circuits Using Current Mirror Based Leakage Compensating Keeper." Applied Mechanics and Materials 573 (June 2014): 169–75. http://dx.doi.org/10.4028/www.scientific.net/amm.573.169.

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In this work low leakage and high noise immunity domino circuit with negligible speed degradation is proposed. Wide Fan-In Gates are widely used as address decoders in memories. Wide Fan-In Gates increase the capacitance of the dynamic node which reduces the speed in domino circuits. Current contention exists between keeper transistor and evaluation network adding to speed reduction. To overcome this problem logic implementation network in the proposed Leakage Compensating Keeper (LCK) is separated from the dynamic node by current comparison stage in which the current of the pull up network is
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7

Kopylov, Dmitriy, Mark Mendelson, Vadim Egorov, and Vladimir Lyutin. "Decoding LDPC Codes with a Regular Check Matrix Structure Using the Bit Flip Method." Telecom IT 12, no. 1 (2024): 40–56. http://dx.doi.org/10.31854/2307-1303-2024-12-1-40-56.

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Problem statement: low-density LDPC codes have become very popular in modern communication systems, which make it possible to implement decoders for them in practice. In conditions of severe limitations of equipment performance, the task of searching and researching the characteristics of decoding algorithms for these codes is urgent. The aim of the work is to find a simplified algorithm for decoding LDPC codes and to study the noise immunity of the proposed algorithm. The methods used: to solve this problem computer simulation is used to compare the noise immunity of known decoding algorithms
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Krasteva, Vessela, Todor Stoyanov, Ramun Schmid, and Irena Jekova. "Delineation of 12-Lead ECG Representative Beats Using Convolutional Encoder–Decoders with Residual and Recurrent Connections." Sensors 24, no. 14 (2024): 4645. http://dx.doi.org/10.3390/s24144645.

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The aim of this study is to address the challenge of 12-lead ECG delineation by different encoder–decoder architectures of deep neural networks (DNNs). This study compares four concepts for encoder–decoders based on a fully convolutional architecture (CED-Net) and its modifications with a recurrent layer (CED-LSTM-Net), residual connections between symmetrical encoder and decoder feature maps (CED-U-Net), and sequential residual blocks (CED-Res-Net). All DNNs transform 12-lead representative beats to three diagnostic ECG intervals (P-wave, QRS-complex, QT-interval) used for the global delineat
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9

Pykov, E. V., E. P. Stroganova, and S. V. Dvornikov. "A model of a decameter-band noise-proof radio channel with an automatic monitoring system based on a nonparametric statistical test." T-Comm 18, no. 7 (2024): 21–36. https://doi.org/10.36724/2072-8735-2024-18-7-21-36.

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Purpose: the task of increasing the reliability, noise immunity and noise immunity of a radio signal at the stages of developing channel-forming radio communication means in the decameter range of radio waves can be solved on the basis of improving the methods of receiving and processing a radio sig nal. The medium of propagation of radio waves in the decameter range is characterized by statistically heterogeneous physical parameters. Thus, based on solving the problems of statistical communication theory, it is possible to determine the main parameters of the projected communication channels.
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10

Lim, Kok Haw Jonathan, Evangelos Giampazolias, Oliver Schulz, et al. "Loss of secreted gelsolin enhances response to anticancer therapies." Journal for ImmunoTherapy of Cancer 10, no. 9 (2022): e005245. http://dx.doi.org/10.1136/jitc-2022-005245.

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Type 1 conventional dendritic cells (cDC1) play a critical role in priming anticancer cytotoxic CD8+ T cells. DNGR-1 (a.k.a. CLEC9A) is a cDC1 receptor that binds to F-actin exposed on necrotic cancer and normal cells. DNGR-1 signaling enhances cross-presentation of dead-cell associated antigens, including tumor antigens. We have recently shown that secreted gelsolin (sGSN), a plasma protein, competes with DNGR-1 for binding to dead cell-exposed F-actin and dampens anticancer immunity. Here, we investigated the effects of loss of sGSN on various anticancer therapies that are thought to induce
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11

BOIKO, J., I. PYATIN, and A. ZAIETS. "MODELS OF NOISELESS CODING SYSTEMS IN TELECOMMUNICATIONS." Herald of Khmelnytskyi National University. Technical sciences 287, no. 4 (2020): 174–83. https://doi.org/10.31891/2307-5732-2020-287-4-174-183.

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The paper presents the results of the synthesis and analysis of a possible scenario for decoding low-density parity-check codes. The principles of decoding low-density parity-check codes based on the turbo approach are considered. The modern communication theory is based on a scientific task, the essence of which is based on the synthesis of a model of information transfer from an information source to a receiver based on its spatial or temporal dislocation. We will design the decoder based on the “turbo” approach on the basis that the modulation and code will be processed in the receiving dev
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12

Eppler, Haleigh B., and Christopher M. Jewell. "Biomaterials as Tools to Decode Immunity." Advanced Materials 32, no. 13 (2019): 1903367. http://dx.doi.org/10.1002/adma.201903367.

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13

Li, Shitao, Lingyan Wang, and Martin Dorf. "Proteomics decode RLR and TLR signaling circuitry (136.5)." Journal of Immunology 184, no. 1_Supplement (2010): 136.5. http://dx.doi.org/10.4049/jimmunol.184.supp.136.5.

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Abstract RIG-I-like receptors (RLRs) and Toll-Like Receptors (TLRs) play a critical role in sensing microorganisms and activating the early innate immune response. The signaling circuit of innate immunity remains incompletely understood. To systematically investigate the network, we initiated a global proteomic analysis of protein complexes found in the innate immunity pathway. Fifty-five genes involved in TLR and RLR pathways were tagged with FLAG epitopes and stably transfected into 293 cells engineered to express TLR3 or TLR4. After treatment with or without poly(I:C), LPS, or poly(dA:dT),
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14

Simeonov, Dimitre R., and Alexander Marson. "CRISPR-Based Tools in Immunity." Annual Review of Immunology 37, no. 1 (2019): 571–97. http://dx.doi.org/10.1146/annurev-immunol-042718-041522.

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CRISPR technology has opened a new era of genome interrogation and genome engineering. Discovered in bacteria, where it protects against bacteriophage by cleaving foreign nucleic acid sequences, the CRISPR system has been repurposed as an adaptable tool for genome editing and multiple other applications. CRISPR's ease of use, precision, and versatility have led to its widespread adoption, accelerating biomedical research and discovery in human cells and model organisms. Here we review CRISPR-based tools and discuss how they are being applied to decode the genetic circuits that control immune f
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15

Jordanova, L., L. Laskov, and D. Dobrev. "Influence of BCH and LDPC Code Parameters on the BER Characteristic of Satellite DVB Channels." Engineering, Technology & Applied Science Research 4, no. 1 (2014): 591–95. http://dx.doi.org/10.48084/etasr.394.

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This article presents the results of a study on the noise immunity of DVB channels when higher-order M-ary APSK modulation schemes and concatenated BCH-LDPC codes are used. Dependencies to determine the probability at the decoder output are given taking into consideration the BCH and LDPC code parameters and the error probability in the communication channel. The influence of the BCH packets length, the BCH code rate, the number of maximum iteration and the parameters of LDPC parity-check matrix on the code efficiency is analyzed. Research of the influence of the concatenated LDPC-BCH code par
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16

Jordanova, L., L. Laskov, and D. Dobrev. "Influence of BCH and LDPC Code Parameters on the BER Characteristic of Satellite DVB Channels." Engineering, Technology & Applied Science Research 4, no. 1 (2014): 591–95. https://doi.org/10.5281/zenodo.14036.

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This article presents the results of a study on the noise immunity of DVB channels when higher-order M-ary APSK modulation schemes and concatenated BCH-LDPC codes are used. Dependencies to determine the probability at the decoder output are given taking into consideration the BCH and LDPC code parameters and the error probability in the communication channel. The influence of the BCH packets length, the BCH code rate, the number of maximum iteration and the parameters of LDPC parity-check matrix on the code efficiency is analyzed. Research of the influence of the concatenated LDPC-BCH code par
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17

Matsenko, S., O. Borysenko, S. Spolitis, and V. Bobrovs. "Noise Immunity of the Fibonacci Counter with the Fractal Decoder Device for Telecommunication Systems." Latvian Journal of Physics and Technical Sciences 56, no. 5 (2019): 12–21. http://dx.doi.org/10.2478/lpts-2019-0027.

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Abstract The paper presents the improved method of noise immune Fibonacci counting in the minimal form of representation. The method was tested and investigated in the developed noise immune pulse counter based on a minimal form of Fibonacci code with a fractal decoding device. The proposed device, which is simulated in the NI Multisim software, possesses a homogenous structure, increased noise immunity, performance and detection of bit errors in the process of its operation.
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18

B.Salih, Arshad, Ayoub Esam Kamal, and Zuhair Shakor Mahmood. "Design of TCM decoder for accurate detection on AWGN and Rayleigh environments." International Journal of Engineering & Technology 7, no. 4 (2019): 5156–59. http://dx.doi.org/10.14419/ijet.v7i4.20746.

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Wireless communications are made an expanded growth during the last decade. Channel is importantly considerable in communication studies where signals are fading and attenuated due to channel disturbances. Today’s technologies are completely relying on digital signals by adapting devices which understand only digital representation of data. Such techniques shrink the energy required to operate the devices and reduced the cost of deploying such systems in personal and industrial fields. Encryption of data and preparing the signal with good immunity for noise are the main subjects in this pape
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19

Sadchenko, A. V., O. A. Kushnirenko, A. G. Yurkevych, and V. S. Sevastianov. "Study of the corrective ability of sync codes for the matched processing decoder." Технология и конструирование в электронной аппаратуре, no. 5-6 (2018): 17–23. http://dx.doi.org/10.15222/tkea2018.5-6.17.

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Increase of the operation reliability of the frame synchronization schemes of communication systems affected by interferences might be achieved by using sync sequences optimal according to the minimax criterion and having the best ratio of the maximum side-lobe level to the main peak of the non-periodic autocorrelation function. Obviously, the longer the minimax sequence, the higher its correction ability. However, with the increase in the length of the sync code, a conflict arises between the corrective ability and the speed of data transfer. This is caused by the decrease in the duration of
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20

Dr.Reshmi.R. "The clinical implications of Hypoxia Inducible Factor -A Nobel approach." INTERNATIONAL JOURNAL OF NOVEL RESEARCH AND DEVELOPMENT 8, no. 11 (2023): c207—c216. https://doi.org/10.5281/zenodo.10399411.

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     The Nobel prize winning discovery of Hypoxia Inducible factors, has paved the way for understanding the pathophysiology of Hypoxia, Anemia in Chronic Kidney Disease, Polycythemia vera, Systemic hypertension in Obstructive sleep apnea, Carcinogenesis and much more. The discovery also helped in the development of HIF stabilisers and Inhibitors promises a bright future in the treatment of the many  diseases ,especially cancer,heart failure,anemia and in wound healing . The effect of hypoxia in the covid survivors are yet to be decoded.
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21

Yong, Daniel, Dan Corral, and Yasmine Belkaid. "Dynamics of lymphoid-mammary epithelial cell interaction during pregnancy and lactation." Journal of Immunology 210, no. 1_Supplement (2023): 150.16. http://dx.doi.org/10.4049/jimmunol.210.supp.150.16.

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Abstract Breast milk has been shown to play a key role in the transfer of immunity from mother to offspring. Antibodies and lymphoid cells can be passed through breast milk and impact offspring immunity. However, the role of these lymphoid cells in lactation and in the control of offspring immunity remains unclear. We observed that the lymphoid cells present in the breast milk are distinct from those found in the blood. Compared to the blood, breast milk T cells are enriched in a T-bet +unconventional population. Imaging analysis revealed that these T-bet +cells gradually accumulate in the mam
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22

Tvaroška, Igor. "The Role of Glycans in Human Immunity—A Sweet Code." Molecules 30, no. 13 (2025): 2678. https://doi.org/10.3390/molecules30132678.

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Glycans on the surface of all immune cells are the product of diverse post-translational modifications (glycosylation) that affect almost all proteins and possess enormous structural heterogeneity. Their bioinformational content is decoded by glycan-binding proteins (lectins, GBPs), such as C-type lectins, including selectins, galectins, and Siglecs. Glycans located on the surface of immune cells are involved in many immunological processes through interactions with GBPs. Lectins recognize changes in the glycan epitopes; distinguish among host (self), microbial (non-self), and tumor (modified
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23

Timofeev, Alexander L., Albert Kh Sultanov, Ivan K. Meshkov, and Azat R. Gizatulin. "Increasing the period of active use of on-board electronic equipment of spacecraft." Siberian Aerospace Journal 25, no. 1 (2024): 33–42. http://dx.doi.org/10.31772/2712-8970-2024-25-1-33-42.

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For electronic equipment of space systems, and primarily memory devices, the task of protection from the effects of ionizing cosmic radiation and other external factors that distort stored and processed information is relevant. This paper proposes a holographic coding method that allows you to restore information in the event of a large number of errors. The method is based on recording into memory, instead of the original digital hologram data, a virtual digital object corresponding to a data block. The divisibility property of a hologram is used, which makes it possible to reconstruct a reco
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Bhowal, Sayak. "Speed, Noise Immunity, Power Consumption and Area Comparison between Different Approaches of Low-Power Viterbi Decoder for Digital Wireless Communication Applications." Network Protocols and Algorithms 6, no. 1 (2014): 19. http://dx.doi.org/10.5296/npa.v6i1.4759.

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25

Mendoza Castro, Jesus Hernan, Carlos Fernando Diaz Meza, Cristian Hernando Acevedo, Yezid Torres Moreno, and Jaime Guillermo Barrero. "Data decoding of integer orbital angular momentum beams based in straight edge diffraction nanometric film." DYNA 86, no. 209 (2019): 170–79. http://dx.doi.org/10.15446/dyna.v86n209.74129.

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The orbital angular momentum revolutionized optical communications, like an OAM beam of light need not be interrupted for the transfer ofdata, provides immunity to electromagnetic interference, allows increase bandwidth, rate and transmission capacity information, making theprocess more efficient. Supported by the ability to encode information on OAM modes of light, is necessary the development of a decoder thatintegrate to hardware systems, solve the problem of current techniques, which main disadvantage is to require the use of additional energysources, increasing the implementation cost, an
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Jiang, Aimin, Juelan Ye, Ye Zhou, et al. "Copper Death Inducer, FDX1, as a Prognostic Biomarker Reshaping Tumor Immunity in Clear Cell Renal Cell Carcinoma." Cells 12, no. 3 (2023): 349. http://dx.doi.org/10.3390/cells12030349.

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Background: Progress in the diagnosis and treatment of clear cell renal cell carcinoma (ccRCC) has significantly prolonged patient survival. However, ccRCC displays an extreme heterogenous characteristic and metastatic tendency, which limit the benefit of targeted or immune therapy. Thus, identifying novel biomarkers and therapeutic targets for ccRCC is of great importance. Method: Pan cancer datasets, including the expression profile, DNA methylation, copy number variation, and single nucleic variation, were introduced to decode the aberrance of copper death regulators (CDRs). Then, FDX1 was
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27

Fomin, A. V., V. V. Voznyuk, and V. M. Baranov. "APPLICATION OF COMPUTER MODELING TO ASSESS THE NOISE IMMUNITY OF DIGITAL COMMUNICATION LINES WITH M-ARY FREQUENCY-SHIFT-KEYED." Vestnik komp'iuternykh i informatsionnykh tekhnologii, no. 198 (December 2020): 20–28. http://dx.doi.org/10.14489/vkit.2020.12.pp.020-028.

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The article considers the process of unintended noise interference with variable frequency and spectrum width values on a digital communication line with multi-position frequency manipulation. To conduct research in the modeling environment Matlab developed software model allows to estimate the influence of noise of various structures to receive signals from multiple frequency shift keying and obtain the dependence of the probability of bit error against signal-to-noise. The transmitter model allows you to generate a high-frequency signal manipulated by the frequency of an information message,
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28

Saqib, Muhammad,, Najma Bibi, and Sawaira Bibi. "DIVERSITY OF RIBONUCLEIC ACID (RNA) VIRUS ENDOGENOUS VIRAL ELEMENTS (EVEs) IN INSECT GENETIC MATERIAL." Pakistan Journal of Biotechnology 19, no. 1 (2022): 1–8. http://dx.doi.org/10.34016/pjbt.2022.19.1.8.

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Many different RNA viruses infect insects, but the capacity to transmit to a single or numerous host species sets them apart. Through recipient transcription and replication, viral chromosomes may be incorporated into their host genes, resulting in the emergence of endogenous viral elements (EVEs). It has proven possible to find RNA virus EVEs in various of insect genomes with varying evolutionary paths, from extremely damaged genetic remnants to partial and full viral coding sections, in several different insects.Insect–virus contact has benefited much from research on these EVE, such as deve
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29

De Lima, Jader A., Sidnei F. Silva, Adriano S. Cordeiro, and Michel Verleysen. "A CMOS/SOI Single-input PWM Discriminator for Low-voltage Body-implanted Applications." VLSI Design 15, no. 1 (2002): 469–76. http://dx.doi.org/10.1080/1065514021000012075.

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A CMOS/SOI circuit to decode Pulse-Width Modulation (PWM) signals is presented as part of a body-implanted neurostimulator for visual prosthesis. Since encoded data is the sole input to the circuit, the decoding technique is based on a novel double-integration concept and does not require low-pass filtering. Non-overlapping control phases are internally derived from the incoming pulses and a fast-settling comparator ensures good discrimination accuracy in the megahertz range. The circuit was integrated on a 2 μm single-metal thin-film CMOS/SOI fabrication process and has an effective area of 2
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30

Kumari, Diksha, Bishun Deo Prasad, Sangita Sahni, Heather M. Nonhebel, and Priti Krishna. "The Expanded and Diversified Calmodulin-Binding Protein 60 (CBP60) Family in Rice (Oryza sativa L.) Is Conserved in Defense Responses against Pathogens." Agronomy 12, no. 12 (2022): 3060. http://dx.doi.org/10.3390/agronomy12123060.

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Plant disease management is key to sustainable production of staple food crops. Calcium (Ca2+) signal and phytohormones play critical roles in regulating plant defense responses against pathogens. The Ca2+ signals are sensed, decoded and transduced by calmodulin and other Ca2+ -binding proteins, followed by interaction with and modulation of activities of target proteins such as calmodulin-binding proteins (CBPs). Members of the Arabidopsis CBP60 gene family, AtCBP60g and AtSARD1, have emerged as major regulators of immune responses. In this study, we identified a 15 member CBP60 gene family i
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O., O. HOLOLOBOVA, and I. HAVRYLIUK V. "APPLICATION OF FOURIER TRANSFORM AND WAVELET DECOMPOSITION FOR DECODING THE CONTINUOUS AUTOMATIC LOCOMOTIVE SIGNALING CODE." Science and Transport Progress, no. 1(67) (February 13, 2017): 7–17. https://doi.org/10.15802/stp2017/92771.

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<strong>Purpose.&nbsp;</strong>The existing system of automatic locomotive signaling (ALS) was developed at the end of the last century. This system uses the principle of a numerical code which is implemented on the basis of relay engineering, and therefore, it is exposed to various types of interferences. Over the years, the system has been upgraded several times, but the causes of faults and failures in its operation are still the subject of research. It is known that the frequency and the phase modulation of signal has a higher interference immunity as compared to the amplitude modulation.
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Chakraborty, Avirup, Changlin Yang, Diana Feier, et al. "TMIC-52. DECODING METABOLIC INTERACTIONS IN GLIOBLASTOMA TUMOR MICROENVIRONMENT THROUGH COMPREHENSIVE SPATIAL TRANSCRIPTOMIC AND PROTEOMIC ANALYSIS." Neuro-Oncology 26, Supplement_8 (2024): viii310. http://dx.doi.org/10.1093/neuonc/noae165.1230.

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Abstract INTRODUCTION Within the GBM microenvironment, distinct micro-niches arise from independent cancer cell lineages with unique metabolic needs, characterized as Fast Cycling Cells (FCCs) and Slow Cycling Cells (SCCs). FCCs preferentially utilize aerobic glycolysis for energy, whereas treatment-resistant SCCs depend on lipid metabolism. Our study decodes the molecular and spatial heterogeneity within the GBM microenvironment, focusing on the dichotomy of immune infiltrates and the metabolic interactions between SCCs and the immune compartment in human GBM patients. METHODS We performed sp
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Klapashchuk, Ihor, and Andrii Veryha. "Analysis of Amateur Radio Frequency Code Modulation Protocols for Transmitting Short Messages." Security of Infocommunication Systems and Internet of Things 2, no. 2 (2024): 02005. https://doi.org/10.31861/sisiot2024.2.02005.

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The article is dedicated to analyzing common short message transmission protocols in digital code used by radio amateurs in amateur radio communication. The following protocols are considered: RTTY, AMTOR, PACTOR1, ISCAT, JT4, JT9, JT65, FT4, and FT8. All of them use frequency shift keying (FSK), which provides significantly better noise resistance since information is encoded in frequency changes rather than amplitude. Because of this, FM is widely used in broadcasting. The primary purpose of the listed protocols is to prevent signal fading due to radio wave reflection from the ionospheric la
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34

Timofeev, Aleksandr L., Albert Kh Sultanov, Ivan K. Meshkov, and Azat R. Gizatulin. "Increasing the positioning accuracy of the GLONASS system." Siberian Aerospace Journal 25, no. 4 (2024): 482–92. https://doi.org/10.31772/2712-8970-2024-25-4-482-492.

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The accuracy of determining coordinates in global positioning systems is determined by the number of satellites simultaneously visible to the consumer's navigation equipment. Over most of the earth's surface, there are up to 11 GLONASS satellites above the horizon at the same time, but the signal-to-noise ratio in the communication channel required for error-free information reception is often ensured only for 2-4 satellites. To improve the positioning accuracy, it is proposed to use the holographic noise-immune coding method based on the holographic representation of the digital signal. The m
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Asim, Muhammad Nabeel, Muhammad Ali Ibrahim, Muhammad Imran Malik, Andreas Dengel, and Sheraz Ahmed. "LGCA-VHPPI: A local-global residue context aware viral-host protein-protein interaction predictor." PLOS ONE 17, no. 7 (2022): e0270275. http://dx.doi.org/10.1371/journal.pone.0270275.

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Viral-host protein protein interaction (PPI) analysis is essential to decode the molecular mechanism of viral pathogen and host immunity processes which eventually help to control viral diseases and optimize therapeutics. The state-of-the-art viral-host PPI predictor leverages unsupervised embedding learning technique (doc2vec) to generate statistical representations of viral-host protein sequences and a Random Forest classifier for interaction prediction. However, doc2vec approach generates the statistical representations of viral-host protein sequences by merely modelling the local context o
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36

Akram, Muhammad, Isaac John Umaru, Abid Mahmood, et al. "Modern Microbiology: Exploring Microbial Frontiers in Health, Environment, and Biotechnology." Kwaghe International Journal of Sciences and Technology 2, no. 2 (2025): 160–67. https://doi.org/10.58578/kijst.v2i2.5818.

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Microbiology, the study of microscopic organisms including bacteria, viruses, fungi, archaea, and protozoa, remains one of the most dynamic and transformative disciplines in modern science. It is foundational to understanding diverse biological systems, from molecular genetics to ecosystem function, and is integral to advancements in biotechnology, medicine, and environmental science. The field has expanded significantly with the advent of molecular biology and omics technologies, enabling precise exploration of microbial genetics, physiology, and metabolic networks. Microorganisms, while reco
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Kanwal, Firdos, Khurram Karim Qureshi, Waqas A. Imtiaz, Anwar Ul Haq, and Jawad Mirza. "A Secure Optical Body Area Network Based on Free Space Optics and Time-Delayed 2D-Spectral/Spatial Optical CDMA." Applied Sciences 13, no. 16 (2023): 9347. http://dx.doi.org/10.3390/app13169347.

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Free space optics (FSO)-based optical body area networks (OBANs) are receiving massive attention as an opportunity to address the limitations of their radio frequency (RF)-based counterparts. This boom in research interests is primarily due to multitude of benefits, including high capacity, immunity to electromagnetic interference (EMI), rapid installation, cost efficiency, and license-free use of spectrum. Securing the transmission of patient health data against interception in OBANs using insecure FSO channels is a challenging task. Therefore, we propose a low-cost, flexible, and secure OBAN
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Read, James F., and Anthony Bosco. "Decoding Susceptibility to Respiratory Viral Infections and Asthma Inception in Children." International Journal of Molecular Sciences 21, no. 17 (2020): 6372. http://dx.doi.org/10.3390/ijms21176372.

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Human Respiratory Syncytial Virus and Human Rhinovirus are the most frequent cause of respiratory tract infections in infants and children and are major triggers of acute viral bronchiolitis, wheezing and asthma exacerbations. Here, we will discuss the application of the powerful tools of systems biology to decode the molecular mechanisms that determine risk for infection and subsequent asthma. An important conceptual advance is the understanding that the innate immune system is governed by a Bow-tie architecture, where diverse input signals converge onto a few core pathways (e.g., IRF7), whic
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Amin, Rada, Sara Sadat Aghamiri, Bhanwar Lal Puniya, and Tomáš Helikar. "A multiscale mechanistic model of human dendritic cells for in-silico investigation of immune responses and novel therapeutics discovery." Journal of Immunology 210, no. 1_Supplement (2023): 221.22. http://dx.doi.org/10.4049/jimmunol.210.supp.221.22.

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Abstract Given the critical role of dendritic cells (DCs) in shaping immunity, they present an attractive avenue as a therapeutic target to program the immune system and reverse immune disease disorders. DC-mediated immune response grows into a complex continuum of molecular and cellular networks where each scale decides to be later translated into a seamless phenotype. Computational models open novel frontiers in research by integrating large-scale interaction to interrogate the influence of complex biological behavior across scales. The ability of modeling to digest large amounts of biologic
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Perruccio, Katia, Silvia Bozza, Claudia Montagnoli, et al. "Prospects for Dendritic Cell Vaccination Against Fungal Infections in Hematopoietic Transplantation." Blood 104, no. 11 (2004): 2139. http://dx.doi.org/10.1182/blood.v104.11.2139.2139.

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Abstract Dendritic cells (DCs) are uniquely able to initiate and control the immune response to fungi. DCs function at three levels in the manipulation of the immune response to these pathogens: 1) they mount an immediate or innate response to them, for example by producing inflammatory mediators upon capture and phagocytosis; 2) through these preceding innate functions, they decode the fungus-associated information and translate it in qualitatively different Th responses; 3) and they are key in containing and dampening inflammatory responses by tolerization through the induction of regulatory
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Huang, Hongyu, Zize Zhao, Fan Huang, et al. "Abstract 6271: Interactions between CD8+ T cells and tumor cells decode tumor heterogeneity and provide treatment recommendations for colorectal cancer." Cancer Research 85, no. 8_Supplement_1 (2025): 6271. https://doi.org/10.1158/1538-7445.am2025-6271.

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Abstract Introduction: Individual heterogeneity in colorectal cancer (CRC) remains a major challenge in therapy optimization, despite diagnostic and treatment advances. CD8+ T cells, pivotal players in anti-tumor immunity, display diverse functional subtypes shaped by interactions within the tumor microenvironment (TME). However, the specific role of CD8+ T cells in mediating heterogeneity through interacting with CRC cells, as well as their influence on the immune response of CRC, remains poorly understood. Here, we employ multi-transcriptomic analyses to discover the factors underlying patie
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Silver, Aryeh, Diana Feier, Guimei Tian, et al. "TMIC-56. TUMOR CELL ARCHITECTURAL HETEROGENEITY AND SPATIAL INTERACTIONS WITH THE TUMOR IMMUNE MICROENVIRONMENT IN GBM." Neuro-Oncology 24, Supplement_7 (2022): vii283—vii284. http://dx.doi.org/10.1093/neuonc/noac209.1100.

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Abstract INTRODUCTION Glioblastoma (GBM) contains cell populations with distinct metabolic requirements, with fast-cycling cells harnessing aerobic glycolysis, and treatment-resistant slow-cycling cells (SCCs) preferentially engaging lipid metabolism. The interaction between immune and tumor cells, and how their metabolic heterogeneity shapes the immune landscape in GBM has yet to be understood. Objectives: The primary objective of this project is to spatially and molecularly decode the GBM microenvironment heterogeneity with a specific focus on unraveling the metabolic links that underlie the
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Karnik, Isha, Wai Nam Liu, Min Liu, et al. "Abstract 1268: A matter of TIME: Advancing a humanized mouse model to decode tumor immune microenvironment and uncover mechanisms of resistance in soft tissue sarcoma." Cancer Research 85, no. 8_Supplement_1 (2025): 1268. https://doi.org/10.1158/1538-7445.am2025-1268.

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Background: Humanized mouse models are invaluable tools in cancer research. These immunodeficient mice, engrafted with human hematopoietic stem cells (HSCs) allow the exploration of immune dynamics and therapeutic responses in cancer. However, traditional models underrepresent key immune cells, particularly natural killer (NK) cells, which are crucial for anti-tumor immunity. We developed an improved humanized mouse model with optimized NK cell reconstitution to better reflect human immune responses. Using this model, we studied soft tissue sarcoma (STS), a malignancy with an immunosuppressive
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Kolomensky, K. Yu, A. Yu Demidova, and A. S. Kazarinov. "From DVB-S to DVB-S2X: Progress in Standardization of Digital Satellite Broadcasting Systems." Journal of the Russian Universities. Radioelectronics 27, no. 2 (2024): 68–78. http://dx.doi.org/10.32603/1993-8985-2024-27-2-68-78.

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Introduction. The article presents a brief history of the European and international standardization process in the field of digital video broadcasting (DVB) systems as applied to satellite broadcasting. The advantages of new systems are considered. The results of a comparative analysis of their main characteristics in relation to previous versions are given.Aim. To study the current progress in the standardization of digital satellite broadcasting systems, to analyze their new features and capabilities, to compare their main characteristics, and to distinguish the advantages of new systems in
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Ma, Jiaqiang, Yingcheng Wu, Lifeng Ma, et al. "Abstract 3973: Cancer B cell blueprint reveals dysfunctional extra-follicular dominance with therapeutic opportunity." Cancer Research 84, no. 6_Supplement (2024): 3973. http://dx.doi.org/10.1158/1538-7445.am2024-3973.

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Abstract B cells are essential components of humoral immunity but harbor multifaceted functions across cancers. To decode tumor-infiltrating B cells, we generated the B cell blueprint encompassing single-cell transcriptome, BCR repertoire, and chromatin accessibility data across 20 cancer types (483 samples, 266 patients). Strikingly, B cells harbored extraordinary heterogeneity and composed of 15 subsets, which were grouped into two independent developmental paths (extra-follicular [EF] versus germinal-center [GC]) exhibiting organ preference. Of note, colon adenocarcinoma and hepatocellular
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Jurkowska-Gomułka, Agata. "How to Throw the Baby out with the Bath Water. A Few Remarks on the Currently Accepted Scope of Civil Liability for Antitrust Damages." Yearbook of Antitrust and Regulatory Studies 8, no. 12 (2015): 61–77. http://dx.doi.org/10.7172/1689-9024.yars.2015.8.12.3.

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The Damages Directive introduces the right to ‘full compensation’ and the principle of ‘joint and several liability’ for antitrust damages (Article 3(1) and Article 11(1) respectively). The Directive does not determine the type of damage that can be awarded in civil proceedings. In theory, there are thus no barriers to establish punitive, multiple or other damages. In practice, it is rather unlikely that such types of damages will be awarded after the implementation of the Directive due to the ban placed on overcompensation in its Article 2(3). This paper will try to decode the concept of ‘ful
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Stojanović, Radovan, Jovan Đurković, Mihailo Vukmirović, Blagoje Babić, Vesna Miranović, and Andrej Škraba. "Medical Data over Sound—CardiaWhisper Concept." Sensors 25, no. 15 (2025): 4573. https://doi.org/10.3390/s25154573.

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Data over sound (DoS) is an established technique that has experienced a resurgence in recent years, finding applications in areas such as contactless payments, device pairing, authentication, presence detection, toys, and offline data transfer. This study introduces CardiaWhisper, a system that extends the DoS concept to the medical domain by using a medical data-over-sound (MDoS) framework. CardiaWhisper integrates wearable biomedical sensors with home care systems, edge or IoT gateways, and telemedical networks or cloud platforms. Using a transmitter device, vital signs such as ECG (electro
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Song, Yuxuan, Yun Peng, Caipeng Qin, et al. "Fibroblast growth factor receptor 3 mutation attenuates response to immune checkpoint blockade in metastatic urothelial carcinoma by driving immunosuppressive microenvironment." Journal for ImmunoTherapy of Cancer 11, no. 9 (2023): e006643. http://dx.doi.org/10.1136/jitc-2022-006643.

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BackgroundImmune checkpoint blockade (ICB) therapy holds promise in metastatic urothelial carcinoma (UC). Fibroblast growth factor receptor 3 (FGFR3) mutation drives T-cell-depleted microenvironment in UC, which led to the hypothesis that FGFR3 mutation might attenuate response to ICB in patients with metastatic UC. The study aims to compare prognosis and response between patients with FGFR3-mutated and FGFR3-wildtype metastatic UC after ICB therapy, and decode the potential molecular mechanisms.MethodsBased on the single-arm, multicenter, phase 2 trial, IMvigor210, we conducted a propensity s
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Lewis, Zachary R., Tien Phan-Everson, Gary Geiss, et al. "Abstract 3878: Subcellular characterization of over 100 proteins in FFPE tumor biopsies with CosMx Spatial Molecular Imager." Cancer Research 82, no. 12_Supplement (2022): 3878. http://dx.doi.org/10.1158/1538-7445.am2022-3878.

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Abstract The spatial interactions between the immune system and tumor cells greatly influence antitumoral immunity. Characterization of immune cell composition and infiltration within the tumor niche informs prognosis, drug delivery efficiency, and therapeutic efficacy. However, few methods exist to query large numbers of immune biomarkers at subcellular spatial resolution. The CosMx™ Spatial Molecular Imager is the first platform to demonstrate simultaneous single-cell and subcellular detection of over 100 proteins on standard, biobanked, FFPE tissue samples. This high-plex protein panel dete
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Sukhorukov, Alexander S. "Optimization of signal parameters and discrete-continuous channel with memory to achieve its bandwidth." T-Comm 16, no. 2 (2022): 4–15. http://dx.doi.org/10.36724/2072-8735-2022-16-2-4-15.

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The article is devoted to the definition of the bandwidth of the channel with memory. A discrete-continuous deterministic channel with fixed-band memory DCDCP was chosen as a model. The encoder forms code combinations of discrete in time and continuous in level symbols. At the output of the channel with memory, these combinations turn into implementations of continuous processes. The channel is deterministic, i.e. the parameters of the channel, the set of transmitted and, uniquely corresponding to it, the set of received combinations, are known both on the transmission and on the reception. On
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