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Journal articles on the topic 'Immuno-suppression'

Author: Grafiati

Published: 4 June 2021

Last updated: 24 July 2025

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1

Chandra, Sudesh, P. K. Gupta, Y. P. Singh, and S. C. Mishra. "Immuno-suppression in fluoride exposed goats." Toxicology Letters 95 (July 1998): 176–77. http://dx.doi.org/10.1016/s0378-4274(98)80704-2.

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2

Mommaas, A. "Protection of UV-induced immuno suppression." Journal of the European Academy of Dermatology and Venereology 5, no. 1 (1995): S26. http://dx.doi.org/10.1016/0926-9959(95)95849-v.

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3

Jha, S. S. "Human immuno-suppression therapy in SARS-CoV-2." COVID-19 Special Issue 1, no. 1 (2020): 1–5. http://dx.doi.org/10.18231/j.ijirm.2020.016.

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4

Shakespeare, Rachel, and A. Barney Hawthorne. "Gut-selective immuno suppression to treat inflammatory bowel disease." Gastrointestinal Nursing 16, no. 3 (2018): 40–47. http://dx.doi.org/10.12968/gasn.2018.16.3.40.

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5

Tarr, Melinda J., Richard M. Bauer, and Richard G. Olsen. "Effects of 1,1-dimethylhydrazine on corynebacterium parvum-induced immuno-suppression." Toxicology 47, no. 1-2 (1987): 229–30. http://dx.doi.org/10.1016/0300-483x(87)90199-5.

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6

Reddy, Pavan, Yoshinobu Maeda, Raimon Duran-Struuck, Oleg Krijanovski, Charles Dinarello, and James L. Ferrara. "Histone Deacetylase Inhibitors Induce Immuno-Dominant Suppression of Dendritic Cells." Blood 106, no. 11 (2005): 456. http://dx.doi.org/10.1182/blood.v106.11.456.456.

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Abstract We and others have recently demonstrated that suberoylanilide hydroxamic acid (SAHA), a histone deacetylase (HDAC) inhibitor with anti-neoplastic properties, reduces experimental acute graft-versus-host disease (GVHD). We have now investigated the mechanisms of action of two HDAC inhibitors, SAHA and ITF 2357, on allogeneic immune responses. Bone marrow derived dendritic cells (DCs) were preincubated with the HDAC inhibitors at nanomolar concentrations for 16–18 hours and stimulated with lipopolysaccharide (LPS). Pretreatment of DCs caused a significant reduction in the secretion of T

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7

Carrieri, Maria Patrizia, François Raffi, Charlotte Lewden, et al. "Impact of Early versus Late Adherence to Highly Active Antiretroviral Therapy on Immuno-Virological Response: A 3-Year Follow-Up Study." Antiviral Therapy 8, no. 6 (2002): 585–94. http://dx.doi.org/10.1177/135965350300800606.

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Objective To assess the impact of different patterns of adherence to highly active antiretroviral therapy (HAART), in particular, the relative impact of early and late adherence, on long-term immuno-virological response in HIV-infected individuals started on a protease inhibitor-containing regimen. Design Clinical, immuno-virological and self-reported adherence data were collected at 4 (M4), 12 (M12), 20 (M20), 28 (M28) and 36 (M36) months after HAART initiation in the French APROCO cohort. Methods A standardized self-administered questionnaire classified patients as non-adherent, moderately o

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8

Cynober, Luc A. "Do We Have Unrealistic Expectations of the Potential of Immuno-Nutrition?" Canadian Journal of Applied Physiology 26, S1 (2001): S36—S44. http://dx.doi.org/10.1139/h2001-040.

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Heavy sports training schedules and competition is often associated with immuno-suppression, and so there is a theoretical justification for providing athletes with nutrients that display immuno-regulatory properties. Among such immuno-nutrients, considerable attention has been paid in recent years to two amino acids, arginine (ARG) and glutamine (GLN). ARG and GLN availability regulate the function ofT lymphocytes, macro phages and polymorphonuclear cells. ARG acts through nitric oxide and polyamine synthesis. The mechanism of action of GLN in immune cells remains unclear. Experience in clini

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9

Merselis, Daniel G., Diego Lirman, and Mauricio Rodriguez-Lanetty. "Symbiotic immuno-suppression: is disease susceptibility the price of bleaching resistance?" PeerJ 6 (April 17, 2018): e4494. http://dx.doi.org/10.7717/peerj.4494.

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Accelerating anthropogenic climate change threatens to destroy coral reefs worldwide through the processes of bleaching and disease. These major contributors to coral mortality are both closely linked with thermal stress intensified by anthropogenic climate change. Disease outbreaks typically follow bleaching events, but a direct positive linkage between bleaching and disease has been debated. By tracking 152 individual coral ramets through the 2014 mass bleaching in a South Florida coral restoration nursery, we revealed a highly significant negative correlation between bleaching and disease i

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10

Politt, D., B. Heintz, J. Floege, and P. R. Mertens. "Tacrolimus- (FK 506) based immuno-suppression in severe systemic lupus erythematosus." Clinical Nephrology 62, no. 07 (2004): 49–53. http://dx.doi.org/10.5414/cnp62049.

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11

Santiesteban, Gretel Maria Torres, Rajan Bhandari, Heetaek Yang, et al. "Reprograming of Tumor-Associated Macrophages in Human BrafV600EMutant Melanoma." Journal of Immunology 204, no. 1_Supplement (2020): 242.27. http://dx.doi.org/10.4049/jimmunol.204.supp.242.27.

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Abstract Melanoma tumors are highly immunogenic, making them an attractive target for immunotherapy. However, many patients do not mount robust clinical responses to targeted therapies, which is attributable, at least in part, to suppression of immune responses by tumor-associated macrophages (TAMs) in the tumor microenvironment (TME). Using a human in vitro culture system, we have shown that the synthetic triterpenoid CDDO-Me enhances immune activation by reprogramming macrophages from immuno-suppressive to immuno-stimulatory. CDDO-Me significantly reduced CCL2, VEGF and IL-6 secretion by mac

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12

Lechner, A. J., K. E. Lamprech, C. A. Johanns, and G. M. Matuschak. "BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN IMPROVES SURVIVAL DURING IMMUNO-SUPPRESSION-RELATED BACTERIAL SEPSIS." Shock 3, no. 6 (1995): 51. http://dx.doi.org/10.1097/00024382-199506000-00180.

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13

Lechner, A. J., K. E. Lamprech, C. A. Johanns, and G. M. Matuschak. "BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN IMPROVES SURVIVAL DURING IMMUNO-SUPPRESSION-RELATED BACTERIAL SEPSIS." Shock 3 (June 1995): 51–52. http://dx.doi.org/10.1097/00024382-199506002-00179.

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14

Umeshappa, Channakeshava Sokke, Karam Pal Singh, Roopa Hebbandi Nanjundappa, and Awadh Bihari Pandey. "Apoptosis and immuno-suppression in sheep infected with bluetongue virus serotype-23." Veterinary Microbiology 144, no. 3-4 (2010): 310–18. http://dx.doi.org/10.1016/j.vetmic.2010.02.033.

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15

Hoppstädter, Jessica, and Alexandra K. Kiemer. "Glucocorticoid-induced leucine zipper (GILZ) in immuno suppression: master regulator or bystander?" Oncotarget 6, no. 36 (2015): 38446–57. http://dx.doi.org/10.18632/oncotarget.6197.

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16

Zheng, Shijun, Yongqiang Wang, Zhonghua Li, Xiaoqi Li, and Hong Cao. "Engagement of Glucocorticoid-induced leucine zipper (GILZ) with Infectious Bursal Disease virus (IBDV) VP4 suppresses type I interferon expression and enhances IBDV growth in host cells (168.13)." Journal of Immunology 188, no. 1_Supplement (2012): 168.13. http://dx.doi.org/10.4049/jimmunol.188.supp.168.13.

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Abstract Infectious Bursal Disease (IBD) is an acute, highly contagious and immunosuppressive avian disease caused by IBD virus (IBDV). Although IBDV-induced immuno-suppression has been well-established, the exact molecular mechanism for such induction is unclear. We report here that IBDV VP4 is an interferon-suppressor by interacting with the Glucocorticoid-induced leucine zipper (GILZ) in host cells. We found that VP4 suppressed the expression of type I interferon in HEK293T cells with Tumor Necrosis Factor(TNF)-α treatment or Sendai virus (SeV) infection, and this suppression could be compl

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17

Agrawal, Ashish. "Sarcoidosis of ocular adenexa." Indian Journal of Ophthalmology - Case Reports 3, no. 3 (2023): 806–7. http://dx.doi.org/10.4103/ijo.ijo_3176_22.

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Sarcoidosis is a chronic inflammatory disease of unknown etiology. Any part of the body may be involved, including eye and/or its adnexal tissues. Uveitis and optic neuropathy are the main manifestations. Patients need immuno-suppression to maintain remission. Patients associated with exclusive extra-ocular involvement (lacrimal glands in our case) need a high degree of suspicion and a multi-disciplinary approach for proper management.

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18

Ding, Peikun, Xiaoxiang Huang, Quanzhou Peng, et al. "Abstract 1597: Immune suppression of the lymph node microenvironment causes oligoprogression of metastatic cancer after neoadjuvant immuno-chemotherapy." Cancer Research 85, no. 8_Supplement_1 (2025): 1597. https://doi.org/10.1158/1538-7445.am2025-1597.

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Abstract Oligometastatic disease is recognized as an intermediate state between localised and systemically metastasised disease. The diagnosis, treatment and prognosis of oligometastatic disease is currently based mainly on imaging examination. Previous clinical studies indicated that standard systemic therapy followed by radical local therapy was beneficial for survival in tumor patients with oligometastatic disease. However, different clinical outcomes (such as oligopersistant and oligoprogression) were found in synchronous and/or metachronous oligometastatic disease after the same systemic

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19

Makino, Toshiaki, Keita Kato, and Hajime Mizukami. "Processed Aconite Root Prevents Cold-Stress-Induced Hypothermia and Immuno-Suppression in Mice." Biological & Pharmaceutical Bulletin 32, no. 10 (2009): 1741–48. http://dx.doi.org/10.1248/bpb.32.1741.

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20

Eiwegger, T., S. Gruber, C. Geiger, et al. "Impact of systemic immuno-suppression after solid organ transplantation on allergen-specific responses." Allergy 66, no. 2 (2010): 271–78. http://dx.doi.org/10.1111/j.1398-9995.2010.02475.x.

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21

Adeolu, AA, MT Shokunbi, AO Malomo, EA Akang, MO Obajimi, and EO Komolafe. "Solitary intracranial tuberculoma in patients without immuno-suppression: a report of three cases." Nigerian Postgraduate Medical Journal 13, no. 1 (2006): 69. http://dx.doi.org/10.4103/1117-1936.180441.

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22

MARTYNOV, A. I. "MODULATORY EFFECT OF PREDOMINATELY PHYSICAL NATURE FACTORS ON HUMAN AND ANIMAL IMMUNE SYSTEMS (PART 1)." Russian Journal of Allergy 11, no. 4 (2014): 3–11. http://dx.doi.org/10.36691/rja582.

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The review presents the data on mechanical vibration and two types of non-ionizing radiation influence on im- munological reactivity of the organism. Mechanical vibration causes a cell immunity suppression and immuno- pathological syndromes development. li EMr activates t-lymphocytes and increases expression of il-1b, iFn-g and tnFa genes which determine anti-inflammatory effect. li lr has hormesis effect: it`s small doses activate immunocyte and cytokine production and it`s high doses lead to immunosuppression.

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23

Nidhishree, J. Jakkali* and Mahe Anjum. "A Review: Immunological Approaches In Animal Fertility." Science World a monthly e magazine 3, no. 5 (2023): 683–91. https://doi.org/10.5281/zenodo.7923072.

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Animal fertility is very important when we are concerned about dairy farmers, which can be modulated by some of immunological approaches. This approach uses antigen or antibody in required dose to manipulate fertility by increasing the innate immunological reactions. These approaches can be used for either immuno-enhancement or immuno-suppression with several hormones like GnRH, LH, Inhibin, Androstenedione, etc. As such hormones does not induce immunogenicity, for reliable production of antibodies, the peptide has to be first conjugated to a carrier immunogenic protein molecule. Some of the e

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24

Jha, SS. "Revisiting Characters of Human Immune Orchestra in Light of Immuno-Suppression by Corona Virus." Acta Scientific Orthopaedics 3, no. 5 (2020): 23–25. http://dx.doi.org/10.31080/asor.2020.03.0174.

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25

Jiao, Hena, and Fei Ren. "Pretreatment with Lornoxicam, a Cyclooxygenase Inhibitor, Relieves Postoperative Immuno-Suppression after Total Abdominal Hysterectomy." Tohoku Journal of Experimental Medicine 219, no. 4 (2009): 289–94. http://dx.doi.org/10.1620/tjem.219.289.

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26

Kahan, Barry D. "The three fates of immuno suppression in the next millenium: selectivity, synergy, and specificity." Transplant International 9, no. 6 (1996): 527–34. http://dx.doi.org/10.1111/j.1432-2277.1996.tb00909.x.

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27

Legat, F. J., P. Wolf, L. T. Jaiani, et al. "Increased intraepidermal CGRP correlates with local immuno-suppression after repeated broadband and narrowband UVB." Experimental Dermatology 13, no. 9 (2008): 585. http://dx.doi.org/10.1111/j.0906-6705.2004.0212bs.x.

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28

MATSUOKA, Takao, Haruo YOSHII, and Seishi SUEHIRO. "Immunological action of Neurotropin. (5). Effect of Neurotropin on immuno-suppression caused by stress." Folia Pharmacologica Japonica 90, no. 1 (1987): 67–71. http://dx.doi.org/10.1254/fpj.90.67.

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29

METTLER, L., A. B. CZUPPON, and H. R. TINNEBERG. "Immunization with Spermatozoal Peptide Antigens Resulting in Immuno-suppression of Fertility Rates in Female Rats." Andrologia 15, no. 6 (2009): 670–75. http://dx.doi.org/10.1111/j.1439-0272.1983.tb00190.x.

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30

FORBES, A., and N. G. READING. "the risks of malignancy from either immuno-suppression or diagnostic radiation in inflammatory bowel disease." Alimentary Pharmacology & Therapeutics 9, no. 5 (2007): 465–70. http://dx.doi.org/10.1111/j.1365-2036.1995.tb00408.x.

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31

Samigullina, R. R., V. I. Mazurov, and E. A. Trofimov. "Characteristics of complex therapy of immuno-inflammatory rheumatic diseases in COVID-19 pandemic conditions." Russian Medical Inquiry 5, no. 5 (2021): 260–67. http://dx.doi.org/10.32364/2587-6821-2021-5-5-260-267.

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The rapid spread of a new coronavirus infection (COVID-19) requires innovative solutions, including tactics optimization in using genetically engineered and targeted drugs in patients with immuno-inflammatory rheumatic diseases (RD). The authors studied the characteristics of the complex therapy of immuno-inflammatory RD in the COVID-19 pandemic conditions, analyzed the COVID-19 course in patients with RD who received combined therapy with genetically engineered and basic synthetic anti-rheumatic drugs and were under follow-up from March 2020 to March 2021. The researchers found that synthetic

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32

Santiesteban, Gretel Maria Torres, Tamer Shabaneh, Rajan Bhandari, Karen Liby, Mary Jo Turk, and Patricia Pioli. "CDDO-Me Redirects Macrophage Activation." Journal of Immunology 202, no. 1_Supplement (2019): 135.17. http://dx.doi.org/10.4049/jimmunol.202.supp.135.17.

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Abstract Melanoma tumors are highly immunogenic, making them an attractive target for immunotherapy. However, many patients do not mount robust clinical responses to targeted therapies, which is attributable, at least in part, to suppression of immune responses by tumor-associated macrophages (TAMs) in the tumor microenvironment (TME). Using a human in vitro culture system, we now show that the synthetic triterpenoid CDDO-Me enhances immune activation by reprogramming macrophages from immuno-suppressive to immuno-stimulatory. CDDO-Me treatment inhibits surface marker expression of CD16 and CD1

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33

Gilhus, Nils Erik. "Lambert-Eaton Myasthenic Syndrome; Pathogenesis, Diagnosis, and Therapy." Autoimmune Diseases 2011 (2011): 1–5. http://dx.doi.org/10.4061/2011/973808.

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Lambert-Eaton Myasthenic Syndrome (LEMS) is a rare disease with a well-characterized pathogenesis. In 50% of the patients, LEMS is a paraneoplastic manifestation and caused by a small cell lung carcinoma (SCLC). Both LEMS patients with SCLC and those without this tumour have in 85% of cases pathogenetic antibodies of very high LEMS specificity against voltage-gated calcium channels (VGCCs) in the cell membrane of the presynaptic motor nerve terminal. Better understanding of LEMS pathogenesis has lead to targeted symptomatic therapy aimed at the neuromuscular junction and to semispecific immuno

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34

Greer, A. W., M. Stankiewicz, N. P. Jay, R. W. McAnulty, and A. R. Sykes. "The effect of concurrent corticosteroid induced immuno-suppression and infection with the intestinal parasite Trichostrongylus colubriformis on food intake and utilization in both immunologically naïve and competent sheep." Animal Science 80, no. 1 (2005): 89–99. http://dx.doi.org/10.1079/asc41100089.

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AbstractThe nutritional cost of both the acquisition and maintenance of immunity to gastro-intestinal nematodes was investigated using immunologically naïve 5-month-old lambs and immunologically competent 17-month-old ewes. Within each age cohort, animals were either infected with the equivalent of 80 L3Trichostrongylus colubriformislarvae per kg live weight (LW) per day (IF), similarly infected and concurrently immuno-suppressed with weekly injections of 1·3 mg/kg LW of the glucocorticoid methylprednisolone acetate (ISIF), immuno-suppressed only (IS) or remained as controls (C). Body composit

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35

Oppliger, A., M. S. Giorgi, A. Conelli, M. Nembrini, and H. B. John-Alder. "Effect of testosterone on immunocompetence, parasite load, and metabolism in the common wall lizard (Podarcis muralis)." Canadian Journal of Zoology 82, no. 11 (2004): 1713–19. http://dx.doi.org/10.1139/z04-152.

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Testosterone can benefit individual fitness by increasing ornament colour, aggressiveness, and sperm quality, but it can also impose both metabolic and immunological costs. However, evidence that testosterone causes immuno suppression in freely living populations is scant. We studied the effects of testosterone on one component of the immune system (i.e., the cell-mediated response to phytohaemagglutinin), parasite load, and metabolic rate in the common wall lizard, Podarcis muralis (Laurenti, 1768). For analyses of immunocompetence and parasitism, male lizards were implanted at the end of the

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36

Vaali, Kirsi, Marja Tuomela, Marika Mannerström, Tuula Heinonen, and Tamara Tuuminen. "Toxic Indoor Air Is a Potential Risk of Causing Immuno Suppression and Morbidity—A Pilot Study." Journal of Fungi 8, no. 2 (2022): 104. http://dx.doi.org/10.3390/jof8020104.

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We aimed to establish an etiology-based connection between the symptoms experienced by the occupants of a workplace and the presence in the building of toxic dampness microbiota. The occupants (5/6) underwent a medical examination and urine samples (2/6) were analyzed by LC-MS/MS for mycotoxins at two time-points. The magnitude of inhaled water was estimated. Building-derived bacteria and fungi were identified and assessed for toxicity. Separate cytotoxicity tests using human THP-1 macrophages were performed from the office’s indoor air water condensates. Office-derived indoor water samples (n

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37

Loureiro, F. C. L., A. M. N. Lima, R. Roque, et al. "Simplified Immuno-assay for Rapid Label-free Dengue Serotype Diagnosis: Suppression of Non-specific Binding Interference." Procedia Technology 27 (2017): 67–69. http://dx.doi.org/10.1016/j.protcy.2017.04.031.

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38

Jiang, Yuyan, Hongbin Cao, Huaping Deng, Li Guan, Jimpi Langthasa, and Quynh-Thu Le. "Abstract PR008: Targeting Galectin-1 to enhance immuno-radiotherapy." Molecular Cancer Therapeutics 23, no. 11_Supplement (2024): PR008. http://dx.doi.org/10.1158/1538-8514.rnadrivers24-pr008.

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Abstract Galectin-1 is overexpressed in a wide range of malignant cancers and is strongly associated with immune suppression as well as cancer aggressiveness. However, effective therapeutics targeting Galectin-1 remain elusive in clinical practice. Herein, we report an activatable nano-system, termed Pr5S, to downregulate Galectin-1 through in vivo gene silencing. Pr5S features a bio-responsive lattice that can protect siRNA during circulation and efficiently break down for gene interference upon exposure to the elevated reductive pressure in the tumor microenvironment. When used independently

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Brennen, W. Nathaniel, Daniel L. J Thorek, Wen Jiang, et al. "Overcoming stromal barriers to immuno-oncological responses via fibroblast activation protein-targeted therapy." Immunotherapy 13, no. 2 (2021): 155–75. http://dx.doi.org/10.2217/imt-2020-0066.

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The tumor microenvironment contributes to disease progression through multiple mechanisms, including immune suppression mediated in part by fibroblast activation protein (FAP)-expressing cells. Herein, a review of FAP biology is presented, supplemented with primary data. This includes FAP expression in prostate cancer and activation of latent reservoirs of TGF-β and VEGF to produce a positive feedback loop. This collectively suggests a normal wound repair process subverted during cancer pathophysiology. There has been immense interest in targeting FAP for diagnostic, monitoring and therapeutic

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40

Leal, M., and E. González de Mejía. "Revisión: Implicaciones toxicológicas y nutricionales de la toxina T-2 / Review: Toxicological and nutritional implications of T-2 toxin." Food Science and Technology International 3, no. 4 (1997): 241–50. http://dx.doi.org/10.1177/108201329700300402.

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Trichothecenes are mycotoxins produced by species of the genus Fusarium. These toxins are associated with health problems in humans and animals. The most common trichothecenes in cereals are deoxynivalenol, HT-2 toxin, diacetoxyscirpenol, nivalenol, neosolaniol and T-2 toxin; the latter is the most widely studied because it is easy to produce in the laboratory. The effects of T-2 toxicosis include dermatonecrosis, reduced body weight and efficiency of food utilization, severe diarrhoea, haemorrhage, necrosis of the upper alimentary tract, anaemia, immuno suppression ; and in birds, poor feathe

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41

Putri Arifin, Reny Faristin, and Wildan Firmansyah. "A case report: Maternal complications from severe dengue. What can happen?" Jurnal Indonesia Sosial Teknologi 5, no. 6 (2024): 2827–33. http://dx.doi.org/10.59141/jist.v5i6.1137.

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Dengue fever (DHF) is an acute infectious disease caused by dengue virus. Thrombocytopenia results from viral suppression in the bone marrow, and platelet destruction occurs. Damaged platelets worsen plasma leakage. When the amount of filtration fluid exceeds the ability and fluid trapped in the interstitium eventually enters the alveoli, there is an increase in alveolar capillaries, resulting in pulmonary oedema. The patient was referred with complaints of fever for 5 days, dizziness (+), shortness of breath (+), nausea (+), and vomiting (+). Laboratory examination showed platelets 109 x 103/

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42

I, Jahan, Dey BP, Akhtaruzzaman M, Hossain KH, Alam M, and Rahman MZ. "Evaluation of PD-L1 Immunoexpression in Resected Samples of Colorectal Adenocarcinoma: A Study on 64 Cases." Journal of Histopathology and Cytopathology 8, no. 01 (2024): 56–64. http://dx.doi.org/10.69950/jhc.2024.v8.i1.08.

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its incidence is rising steadily in developing nations. The patient prognosis for CRC remains poor,despite advances in surgery and treatment. Additionally, there are currently no reliable prognosticapproaches for CRC, despite the use of conventional prognostic factors. Immune checkpointsblockades (ICB) have emerged as a promising treatment strategy and have dramatically improvedlong-term survival in several malignances. The “PD-1 (programmed cell death-1)”/PD-L1(programmed cell death-ligand 1) axis plays an important role to control immune suppression bydown-regulating T effector cell activiti

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43

Hogg, Alison E., Jiaxiang Ji, Katrina L. Lancaster, Miles W. Cloyd, and Janice J. Endsley. "HIV infection inhibits granulysin expression by memory CD8+ T cells (128.26)." Journal of Immunology 182, no. 1_Supplement (2009): 128.26. http://dx.doi.org/10.4049/jimmunol.182.supp.128.26.

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Abstract The hallmark of HIV infection is severe immuno-suppression and an increased susceptibility to many infectious agents including M. tuberculosis. Granulysin is expressed by cytotoxic T cells (CTL) and is strongly lytic against susceptible and drug resistant strains of M. tuberculosis. We hypothesized that the reduced CTL activity observed following HIV infection may, in part, be due to suppression of granulysin. We and others have shown that granulysin expression is regulated by common γc cytokines IL-2, IL-15 and IL-21. We used an in vitro model, in which we infected PBMC from healthy

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&NA;. "CD4+CD25+ T REGULATORY CELLS AND IMMUNO-SUPPRESSION BY CYCLIN KINASE INHIBITOR p21: IS THERE A CONNECTION?" Transplantation 82, Suppl 2 (2006): 880. http://dx.doi.org/10.1097/00007890-200607152-02458.

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Pope, R. M., L. McChesney, N. Stebbing, L. Goldstein, and N. Talal. "Regulation of T cell proliferation by cloned interferon-alpha mediated by Leu-11b-positive cells." Journal of Immunology 135, no. 6 (1985): 4048–53. http://dx.doi.org/10.4049/jimmunol.135.6.4048.

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Abstract The autologous T lymphocyte proliferative response (AMLR) induced by a B lymphocyte-enriched non-T, nonadherent cell population (NT, NAC) and by a macrophage-enriched population were both suppressed by the addition of a cloned interferon-alpha (IFN-alpha Con1) directly to the cultures. Preincubation of the stimulating NT, NAC with IFN-alpha Con1 resulted in comparable suppression. In contrast, preincubation of the macrophages with IFN-alpha Con1 resulted in significant augmentation of T cell proliferation. Depletion of Leu-11b-positive cells from the NT, NAC exposed to IFN-alpha Con1

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Tatiya-aphiradee, Nitima, Waranya Chatuphonprasert, and Kanokwan Jarukamjorn. "Immune response and inflammatory pathway of ulcerative colitis." Journal of Basic and Clinical Physiology and Pharmacology 30, no. 1 (2018): 1–10. http://dx.doi.org/10.1515/jbcpp-2018-0036.

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Abstract Ulcerative colitis (UC) is an idiopathic relapsing inflammatory disease. Although the etiology of UC remains unclear, it could be characterized by inflammation of the intestinal mucosa, starting from the rectum and potentially involving the entire colon. The immune response and inflammatory pathway of UC have shown that tissue damage is driven by dynamic and complexes of cells and cytokines. Various types of cells, including antigen-presenting cells (dendritic cells and macrophages), T helper cells, regulatory T cells, and natural killer T cells, play a crucial role in UC pathogenesis

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47

Hebbandi Nanjundappa, Roopa, and Jim Xiang. "HIV-1-specific exosome targeted CD8+ T cell Vaccine. (45.24)." Journal of Immunology 184, no. 1_Supplement (2010): 45.24. http://dx.doi.org/10.4049/jimmunol.184.supp.45.24.

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Abstract Severe immuno-suppression due to immuno-tolerance and CD4 T cells depletion is the distinguishing feature of HIV-1 infection. Although highly active antiviral therapy (HAART) is available to halt progression of AIDS, it has its own inherent defects, including incomplete protection with associated side effects, and economical concerns. In addition, most of the currently available vaccines fail to induce effective CD8 CTL against HIV-1 in absence of CD4 T cells. Previously, our laboratory showed the efficacy of novel exosome (EXO)-targeted CD4 T cell vaccine (aTexo) with uptake of ova-s

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48

Kamvuma, Kingsley, Yusuf ademola, Warren Chanda, et al. "The Correlation of Tuberculosis Smear Results and Immuno-suppression with CD4+ Counts as Surrogate Among HIV Infected Patients." Acta Scientific Microbiology 5, no. 2 (2022): 02–09. http://dx.doi.org/10.31080/asmi.2022.05.0995.

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49

Shimizu, Kawamura, Miyaji, et al. "Resistance of Extrathymic T Cells to Stress and the Role of Endogenous Glucocorticoids in Stress Associated Immuno Suppression." Scandinavian Journal of Immunology 51, no. 3 (2000): 285–92. http://dx.doi.org/10.1046/j.1365-3083.2000.00695.x.

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50

&NA;. "CARDIOVASCULAR RISK FACTOR AFTER KIDNEY TRANSPLANT WITH PREDNISONE (P)-FREE MAINTENANCE IMMUNO-SUPPRESSION: A COMPARISON OF 3 PROTOCOLS." Transplantation 82, Suppl 2 (2006): 523–24. http://dx.doi.org/10.1097/00007890-200607152-01352.

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