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Dissertations / Theses on the topic 'Immunogenesis'

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1

李嘉輝 and Ka-fai Chris Li. "Immunogenesis of trichinella spiralis (nematoda : trichinelloidea) during muscle phase of development." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1996. http://hub.hku.hk/bib/B31235001.

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2

Li, Ka-fai Chris. "Immunogenesis of trichinella spiralis (nematoda : trichinelloidea) during muscle phase of development /." Hong Kong : University of Hong Kong, 1996. http://sunzi.lib.hku.hk/hkuto/record.jsp?B17505744.

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3

Middleton, D. "Histocompatibility and immunogenetics." Thesis, Queen's University Belfast, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368778.

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4

Foley, Patrick James. "Immunogenetic predisposition in sarcoidosis." Thesis, Imperial College London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.399271.

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5

Fanning, Gregory Charles. "Immunogenetics of systemic sclerosis." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284535.

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6

Thomson, W. "Immunogenetics of rheumatoid arthritis." Thesis, University of Manchester, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.383908.

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7

Saini, Surinder Singh. "Molecular immunogenetics of bovine antibody." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0005/NQ40388.pdf.

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8

Ligers, Arturs. "Immunogenetic studies of multiple sclerosis /." Stockholm : Karolinska Univ. Press, 2001. http://diss.kib.ki.se/2001/91-7349-019-9/.

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9

Anderson, Amy Elizabeth. "The immunogenetics of Helicobacter infection." Thesis, Imperial College London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.414822.

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10

Ghosh, Soumitra. "Immunogenetics of Type I diabetes." Thesis, University of Oxford, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.306514.

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11

Else, Kathryn J. "Immunogenetics of Trichuris muris infection." Thesis, University of Nottingham, 1989. http://eprints.nottingham.ac.uk/12875/.

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Investigations have been made into the genetic control of immunity to the nematode Trichuris muris. Both background genes and genes within the mouse major histocompatibility complex (MHC), H-2, were shown to influence the expulsion of T. muris with the former having the stronger influence. At least two genes within the H-2 complex determined response phenotypes, the effects of "resistance" or "susceptibility" alleles at I-A being modulated by resistance or susceptibility alleles at aD end locus/loci. Differential responsiveness within slowly responding mouse strains suggested that parasite-dep
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12

Tozatto, Maio Karina. "Immunogenetics in sickle cell disease." Thesis, Sorbonne Paris Cité, 2019. http://www.theses.fr/2019USPCC093.

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La drépanocytose est l’hémoglobinopathie héréditaire la plus fréquente, causée par un polymorphisme unique d’un nucléotide (SNP) dans le gène de la beta-globine (HBB). Ce SNP détermine la synthèse de l’hémoglobine S, qui polymérise lorsqu’elle est soumise au stress, et ceci change la forme des hématies drépanocytaires en faucille. Les drépanocytes sont moins déformables, plus adhérents à l’endothélium, et plus susceptibles à l’hémolyse. Les complications cliniques de la drépanocytose peuvent être expliquées par l’interaction entre la vaso-occlusion, l’hémolyse et l’activation inflammatoire rés
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13

Nikitina-Zake, Liene. "Immunogenetic markers in immune-mediated diseases /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-718-5/.

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14

Gambelunghe, Giovanni. "Immunogenetic studies in autoimmune endocrine diseases /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-691-x/.

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15

Wood, Nicholas William. "The immunogenetic basis of multiple sclerosis." Thesis, University of Cambridge, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338015.

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16

Jeffery, Katherine Joanna Mary. "The immunogenetics of HTLV-I infection." Thesis, Imperial College London, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.392152.

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17

Ad'Hiah, Ali H. "Immunogenetic studies in selected human diseases." Thesis, University of Newcastle Upon Tyne, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.261123.

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18

Goodman, Reyna Suzanne. "Immunogenetics of haematopoietic stem cell transplantation." Thesis, Anglia Ruskin University, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.478885.

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19

Korendowych, Eleanor. "An immunogenetic study of psoriatic arthritis." Thesis, University of Bath, 2004. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.407487.

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20

Mullighan, Charles Grenfell. "The immunogenetics of common variable immunodeficiency /." Title page, table of contents and summary only, 1997. http://web4.library.adelaide.edu.au/theses/09MD/09mdm959.pdf.

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21

Helbig, Karla Jayne. "Immunogenetic determinants of chronic Q fever." Title page, table of contents and summary of dissertation only, 2003. http://web4.library.adelaide.edu.au/theses/09PH/09phh4739.pdf.

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"July 2003" Bibliography: leaves 213-244. Q fever, caused by the bacterium Coxiella burnetti, is the most important and costly zoonotic infection in Australia. It manifests in both acute and chronic forms, with the majority of acute Q fever patients making a complete recovery. The strain of C. burnetti has not been found to play a role in the development of chronic Q fever, and it remains unclear why a minority of individuals manifest chronic forms of Q fever, while others make a complete recovery. This study attempts to elucidate possible immunogenetic markers that may contribute to an indivi
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22

Eger, Lars. "Immunogeneic Cell Populations of the Skin." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2008. http://nbn-resolving.de/urn:nbn:de:bsz:14-ds-1213729820693-69540.

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Dendritic cells (DCs), a hematopoietic cell type belonging to the sub-group of cells called antigen presenting cells (APCs), inhabit a central role in innate and adaptive immunity. Although the DC family is very heterogeneous, all members share unique features. Most importantly, DCs can stimulate an immune response. This is due to the cells’ ability to capture and process antigens and to maturate in the presence of danger signals presented by pathogens. Maturation in turn results in the migration of DCs from the tissue they reside in to the draining lymph nodes, as well as in the subsequent pr
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23

Foley, Bree Amanda. "The immunogenetics of natural killer cell alloreactivity." University of Western Australia. School of Pathology and Laboratory Medicine, 2008. http://theses.library.uwa.edu.au/adt-WU2008.0242.

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[Truncated abstract] Natural killer (NK) cell alloreactivity can be exploited in haploidentical haematopoietic stem cell transplantation (HSCT) to improve graft survival, reduce graft versus host disease and decrease leukaemic relapse. NK cells lyse cells that have reduced expression of class I HLA molecules. In an allogeneic setting, donor NK cells may be activated by the absence of donor (self) class I HLA molecules on recipient cells; the absence of self-epitopes being detected by inhibitory KIR receptors on donor NK cells. The way in which genetic polymorphism of the receptors and ligands
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24

Weissert, Robert. "Immunogenetics and treatment of experimental autoimmune encephalomyelitis /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3645-5/.

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25

McCann, Katy. "Immunogenetic analysis of aggressive B-cell malignancies." Thesis, University of Southampton, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.494386.

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26

Hodgkinson, Andrea Dawn. "Immunogenetics of type 1 diabetes in man." Thesis, University of Plymouth, 1999. http://hdl.handle.net/10026.1/1994.

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Genetic susceptibility to type 1 diabetes is associated with the major histocompatibility complex (MHC) on human chromosome 6. To analyse the contribution of the class I region of the MHC to disease susceptibility, polymorphism of the class Ib molecule HLA-E and several genetic markers within the region was investigated in 378 British Caucasoid patients with type 1 diabetes as defined by the National Diabetes Group, 100 multiplex families from the BDA Warren Repository and 216 unselected normal British Caucasoid controls. PCR-Sequence-Specific Oligonucleotide Probing (PCR-SSOP) was used to ana
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27

Risk, Janet Mary. "Immunogenetic studies in pregnancy and recurrent miscarriage." Thesis, University of Liverpool, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.317218.

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28

Caws, Maxine Anna Maria. "The diagnosis and immunogenetics of tuberculous meningitis." Thesis, King's College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271415.

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29

Vacchelli, Erika. "Immunogenetic determinants of chemotherapy response in cancer." Thesis, Paris 11, 2014. http://www.theses.fr/2014PA11T041.

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L’efficacité de la chimiothérapie contre la croissance tumourale repose sur l'induction d'une mort des cellules tumourales dite immunogène. Les cellules tumourales mourantes agissent alors comme un vaccin thérapeutique en stimulant une réponse immunitaire anti-tumourale capable de contrôler, voire d'éliminer, les cellules cancéreuses résiduel. Les trois marqueurs principales de la mort cellulaire immunogène (MCI), sont (i) l'exposition pré-apoptotique de la calréticuline (CRT) à la surface des cellules, (ii) la sécrétion de l'ATP pendant l'apoptose qui dépend du processus d'autophagie, et (iii
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30

Goverdhan, Srinivas. "Immunogenetic pathways in age related macular degeneration." Thesis, University of Southampton, 2008. https://eprints.soton.ac.uk/66006/.

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31

Castro, Prieto Aines del Carmen. "Immunogenetics of free-ranging felids on Namibian farmlands." Phd thesis, Universität Potsdam, 2011. http://opus.kobv.de/ubp/volltexte/2011/5550/.

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Genetic variation is crucial for the long-term survival of the species as it provides the potential for adaptive responses to environmental changes such as emerging diseases. The Major Histocompatibility Complex (MHC) is a gene family that plays a central role in the vertebrate’s immune system by triggering the adaptive immune response after exposure to pathogens. MHC genes have become highly suitable molecular markers of adaptive significance. They synthesize two primary cell surface molecules namely MHC class I and class II that recognize short fragments of proteins derived respectively from
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32

Koskela, R. (Ritva). "Microscopic colitis:clinical features and gastroduodenal and immunogenetic findings." Doctoral thesis, Oulun yliopisto, 2011. http://urn.fi/urn:isbn:9789514294150.

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Abstract The aims of this study were to investigate the clinical features, the endoscopic and histological abnormalities of ileocolonic and gastroduodenal mucosa and immunogenetic background of microscopic colitis (MC) and its subtypes collagenous colitis (CC) and lymphocytic colitis (LC). 30 patients with CC and 54 with LC were examined with different control groups used according to the study. The mean age at diagnosis was in the sixties in both CC and LC, with a female preponderance in both Autoimmune conditions such as celiac diseased (CD) were common in MC. Bronchial asthma associated wit
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33

Agarwal, Kaushik. "Immunogenetic studies in autoimmune and viral liver disease." Thesis, University of Newcastle upon Tyne, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275585.

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34

Wahid, Faisal Numman. "Immunogenetics of Heligmosomoides polygyrus (Nematospiroides dubius) in mice." Thesis, University of Nottingham, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.280098.

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35

Mahdi, Olaimatu Sadia Morenike. "Immunogenetic studies of human ocular Chlamydia trachomatis infections." Thesis, Open University, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300238.

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36

Ivansson, Emma. "Contribution of Immunogenetic Factors in Susceptibility to Cervical Cancer." Doctoral thesis, Uppsala universitet, Institutionen för genetik och patologi, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9552.

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Cervical cancer is the second most common cancer in women worldwide. Persistent infection by an oncogenic type of human papillomavirus (HPV) is a necessary but not sufficient cause and there is also a genetic component. This thesis aims to identify host genetic risk factors for cervical cancer based on the hypothesis that susceptibility is affected by genetic variation in the immune response towards HPV infection. Paper I analyzed allergy in sons and cervical cancer in their mothers, and revealed an inverse association between cervical cancer and allergy across generations. Mothers of allergic
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37

Soutter, Francesca. "Canine leishmaniosis : immunogenetics of response to infection and vaccination." Thesis, Royal Veterinary College (University of London), 2016. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.701667.

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38

Graus, Ivo Maria Franciscus. "Experimental autoimmune myasthenia gravis target organ resistance and immunogenetics /." Maastricht : Maastricht : Universitaire Pers Maastricht ; University Library, Maastricht University [Host], 1992. http://arno.unimaas.nl/show.cgi?fid=6512.

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39

Hawi, Ziarih H. "Serological and molecular immunogenetic studies in selected human diseases." Thesis, University of Newcastle Upon Tyne, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.386885.

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40

Sisay-Joof, Fatoumatta. "Immunogenetic studies on susceptibility of West Africans to malaria." Thesis, Open University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.392869.

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41

Gaynor, Louise Michelle. "Immunogenetic regulation of Natural Killer cell function in pregnancy." Thesis, University of Cambridge, 2017. https://www.repository.cam.ac.uk/handle/1810/270329.

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Uterine NK (uNK) cells are a distinct subset of NK cells in the decidua of humans and rodents during pregnancy, which are essential for remodelling of the spiral arteries supplying the feto-placental unit. Similarly to peripheral NK cells, uNK cells express Natural Killer receptors (NKRs) that engage MHC class I molecules. Evidence from human genetic association studies suggests that, in the presence of allogeneic cognate paternal MHC class I ligands, inhibitory uterine NKRs are associated with disorders of pregnancy arising from impaired decidual vascular remodelling. Conversely, enhancement
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42

Sargent, Carole A. "Molecular mapping of the HLA Class III region." Thesis, University of Oxford, 1988. https://ora.ox.ac.uk/objects/uuid:b208c37f-e2d2-4ad1-a90f-524bff86c17a.

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(a) The class III region of the human MHC is approximately 1.1 Mbp in size. Almost 50% has been cloned in two overlapping cosmid clusters by chromosome walking from the complement/ 210H gene cluster and from the TNF a locus. The complement/ 210H cosmid cluster consists of 45 independent recombinants, spaning 390 kb. The TNFα and TNF β cosmid cluster consists of 16 independent recombinants, spanning 150 kb. Each genomic insert has been characterised by restriction enzyme digestion and Southern blot analysis to produce a detailed restriction map of the cloned region. (b) Single copy D
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43

Basson, Michiel Albertus. "The interaction of HLA Class I molecules with the murine T cell repertoire." Thesis, University of Cambridge, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243059.

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44

Bradbury, Andrew Raymon Morton. "The mouse equivalent of the human thymic antigen CD1." Thesis, University of Cambridge, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.330154.

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45

Anderson, Michael J. "Molecular genetics of the human complement protein C4." Thesis, University of Oxford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.256362.

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46

Ore, Begona Aguado. "Sequence analysis and functional characterisation of three novel genes located in the human major histocompatibility complex." Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.390471.

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47

Lewis, Jonathan William. "The assembly of class I MHC molecules in the endoplasmic reticulum." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.298558.

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48

Foster, Linda S. "Antigen presentation to cytotoxic T cells." Thesis, University of Oxford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.279882.

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49

Chandler, Phillip Richard. "The identification of human minor histocompability antigens." Thesis, Open University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239604.

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50

Palmer, Donald Balfour. "The chromatin structure of the mouse beta-2-microglobulin locus." Thesis, Open University, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.293770.

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