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Journal articles on the topic 'Immunological and hematological studies'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

El-Shimi, Ola Samir, Amina Ali Farag, Amany Mohammed El-Rebigi, Taghrid Gamaleldin Kharboush, Hanaa El-Sayed Bayomy, and Rana Atef Khashaba. "Carbamazepine-Induced Hematological and Immunological Alterations in Egyptian Children with Idiopathic Generalized Seizures." Journal of Child Science 11, no. 01 (2021): e265-e272. http://dx.doi.org/10.1055/s-0041-1736156.

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AbstractCarbamazepine (CBZ) is one of the oldest antiepileptic drugs (AEDs) that is still used for the treatment of tonic-clonic seizures in children. Long-term use of AEDs induces potential toxic effects that may remain undetermined for a long time. Earlier studies have revealed a wide spectrum of hematological toxicities associated with CBZ. This study was conducted to unveil the toxic effects of carbamazepine as an antiepileptic monotherapy on hematological and immunological parameters in a group of Egyptian pediatric patients using it for different durations. Fifty pediatric epileptics of

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Anwar Mawlood, Shilan, and Bakhtiar Mohamed Mahmoud. "Hematological Changes, Serum Interferon Gamma and Interleukin-4 Alterations in Normal Pregnancy and Preeclampsia." International Electronic Journal of Medicine 9, no. 1 (2020): 44–51. http://dx.doi.org/10.34172/iejm.2020.08.

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Background: Various hematological and immunological changes can occur in pregnancy which could be beneficial for the growth of the fetus and the maintenance of the pregnancy although some of these changes could be hazardous to the fetus and can cause complications during pregnancy. Thus, this study was conducted to investigate the hematological and immunological changes in normal pregnancy and preeclampsia (PE). Materials and Methods: To this end, hematological and immunological changes were evaluated in 62 normal pregnant women and 56 pregnant women with PE. Moreover, 58 healthy non-pregnant

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Gebere, Yidnekachew Fiseha, Lealem Gedefaw Bimerew, Wondimagegn Adissu Malko, and Demissie Assegu Fenta. "Hematological and CD4+ T- cell count reference interval for pregnant women attending antenatal care at Hawassa University Comprehensive Specialized Hospital, Hawassa Southern Ethiopia." PLOS ONE 16, no. 4 (2021): e0249185. http://dx.doi.org/10.1371/journal.pone.0249185.

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Background Pregnancy is a state characterized by physiological, hematological, and immunological changes. However, the reference intervals (RI) being used in clinical practice in Ethiopia are derived from non-local general populations. Therefore; this study was aimed to determine the reference interval of hematological and immunological profiles among healthy pregnant mothers attending Hawassa University Hospital. Methods A cross-sectional study in a total of 360 healthy pregnant women was enrolled from January to April 2019, at Hawassa University hospital. Sociodemographic and obstetric data

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Pereira, M. O., A. V. Moraes, J. C. B. Rodhermel, et al. "Supplementation of Curcuma longa hydrolate improves immunomodulatory response in Nile tilapia reared in a recirculation aquaculture system." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 72, no. 5 (2020): 1805–12. http://dx.doi.org/10.1590/1678-4162-11811.

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ABSTRACT The objective of this study was to evaluate the effects of dietary supplementation with different doses of Curcuma longa hydrolate on the hematological, immunological and zootechnical parameters of Nile tilapia cultivated in a recirculation system (RAS). Nile tilapia (Oreochromis niloticus) were used, distributed in 16 polyethylene boxes, divided into four treatments: 0.0%; 2.5%; 7.5% and 10.0% of Curcuma longa hydrolate, in quadruplicate. After 45 days of treatment, four fish per experimental unit were anesthetized to remove blood aliquot for hematological and immunological analyzes

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Miko, Iren, Endre Brath, Norbert Nemeth, et al. "Hematological, hemorheological, immunological, and morphological studies of spleen autotransplantation in mice: Preliminary results." Microsurgery 23, no. 5 (2003): 483–88. http://dx.doi.org/10.1002/micr.10166.

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Bisiuk, V. V., O. Ye Galatiuk, V. L. Behas, Т. О. Romanishina, and A. R. Lakhman. "Hematological parameters and immune response characteristics in canine chlamydiosis." Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies 27, no. 117 (2025): 126–35. https://doi.org/10.32718/nvlvet11718.

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Chlamydiosis is a zoonotic infectious disease caused by bacteria of the genus Chlamydia, characterized by a wide range of clinical manifestations. This study investigates hematological changes and describes certain immunological mechanisms in various clinical forms of the disease. The aim of the research was to analyze hematological parameters and clinical signs in dogs affected by chlamydiosis to determine the relationship between immunological changes and the clinical course of the disease, thereby improving diagnosis and treatment strategies. The study was conducted on 36 dogs diagnosed wit

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Neamat-Allah, Ahmed N. F. "Immunological, hematological, biochemical, and histopathological studies on cows naturally infected with lumpy skin disease." Veterinary World 8, no. 9 (2015): 1131–36. http://dx.doi.org/10.14202/vetworld.2015.1131-1136.

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Denue, Ballah Akawu, Ibrahim Musa Kida, Ahmed Hammagabdo, Ayuba Dayar, and Mohammed Abubakar Sahabi. "Prevalence of Anemia and Immunological Markers in HIV-Infected Patients on Highly Active Antiretroviral Therapy in Northeastern Nigeria." Infectious Diseases: Research and Treatment 6 (January 2013): IDRT.S10477. http://dx.doi.org/10.4137/idrt.s10477.

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Background There are conflicting reports on the impact of highly active antiretroviral therapy (HAART) in resolving hematological complications. Whereas some studies have reported improvements in hemoglobin and other hematological parameters resulting in reduction in morbidity and mortality of HIV patients, others have reported no improvement in hematocrit values of HAART-treated HIV patients compared with HAART-naïve patients. Objective This current study was designed to assess the impact of HAART in resolving immunological and hematological complications in HIV patients by comparatively anal

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Dekhtiarenko, N. О., L. M. Panchenko, M. P. Hrytsai, O. M. Linenko, V. I. Sabadosh, and K. M. Salmanova. "Analysis of Some Immunological Aspects of Joint Infections Developed as a Result of Intra-Articular Glucocorticoid Injection." Visnyk Ortopedii Travmatologii Protezuvannia, no. 4(111) (December 20, 2021): 21–27. http://dx.doi.org/10.37647/0132-2486-2021-111-4-21-27.

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Summary. The work is devoted to the studies of immune status of patients with infectious complications after local glucocorticoid injections. Objective: to assess the state of the immune system of patients with infectious complications after local glucocorticoid injections, to monitor the dynamics of immunological parameters before and after sanitizing surgical treatment, and to reveal factors that are important for predicting the course of the disease and treatment results. Materials and Methods. The immune status of 26 patients with purulent inflammatory processes after local glu

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Gomaa, Soha. "Immunomodulatory and hematological effects induced by diclofenac, ibuprofen or paracetamol toxicity in Swiss albino mice." European Journal of Biological Research 7, no. 4 (2017): 348–59. https://doi.org/10.5281/zenodo.1041933.

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Anti-inflammatory drugs (both COX-2 inhibitors and nonselective non-steroidal anti-inflammatory drugs = NSAIDs), paracetamol and opioid agents are associated with potentially different adverse events with varying degrees of efficacy. The present work was conducted to elucidate the haemato-immunological changes in mice when treated with diclofenac (Diclo), ibuprofen (Ibu) and paracetamol (Para). Mice were intraperitoneally administered with Diclo (7.4 mg/kg and 14.8 mg/kg), Ibu (60 mg/kg and 120 mg/kg) or Para (36.7 mg/kg and 73.4 mg/kg) daily for one month against saline-treated mice served as

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Zhelavskyi, M. M., S. P. Kernychnyi, O. Ya Dmytriv, and T. V. Betlinska. "Adaptive changes in immunological, hematological and metabolic profiles of pregnant cows." Ukrainian Journal of Veterinary and Agricultural Sciences 7, no. 1 (2024): 15–22. http://dx.doi.org/10.32718/ujvas7-1.03.

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Pregnancy triggers a series of complex interactions within the body, involving both the immune system and metabolic processes. In the case of pregnant cows, these mechanisms are essential for supporting the developing fetus and maintaining the overall health of the mother. The aim of the work was to study the hematological, biochemical, and immunological parameters of cows at different periods of pregnancy. Research was conducted on cows (Bos Taurus) of the Ukrainian Black-and-White dairy breed. Groups were formed based on the principle of analogs. The research was carried out using the method

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Akhmedova, V. A. "USE OF MONOCLONAL ANTIBODIES TO HUMAN CYTOKINES IN DIAGNOSTIC AND ANALYTICAL STUDIES." Biotechnologia Acta 17, no. 4 (2024): 24–33. http://dx.doi.org/10.15407/biotech17.04.024.

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The use of human monoclonal antibodies in diagnostics and analytical studies is determined by the rapid development of technologies and approaches in the field of immunology and clinical laboratory diagnostics. Cytokines, as biologically active substances, play a key role in the regulation of immunity, inflammation and other physiological processes. The use of monoclonal antibodies to cytokines provides an opportunity to accurately determine their concentration and study the interaction with other molecules in clinical studies. The development of new diagnostic methods and analytical studies u

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Tolomeo, Manlio, Maria Meli, and Stefania Grimaudo. "STAT5 and STAT5 Inhibitors in Hematological Malignancies." Anti-Cancer Agents in Medicinal Chemistry 19, no. 17 (2020): 2036–46. http://dx.doi.org/10.2174/1871520619666190906160848.

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The JAK-STAT pathway is an important physiologic regulator of different cellular functions including proliferation, apoptosis, differentiation, and immunological responses. Out of six different STAT proteins, STAT5 plays its main role in hematopoiesis and constitutive STAT5 activation seems to be a key event in the pathogenesis of several hematological malignancies. This has led many researchers to develop compounds capable of inhibiting STAT5 activation or interfering with its functions. Several anti-STAT5 molecules have shown potent STAT5 inhibitory activity in vitro. However, compared to th

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Kryachko, O. V., and A. O. Budnik. "Influence of technological stress on the immunological reactivity of piglets." International bulletin of Veterinary Medicine 2 (2020): 155–61. http://dx.doi.org/10.17238/issn2072-2419.2020.2.155.

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Hematological leukocyte indexes reflect the relationship between different classes of cells of the leukocyte formula and can provide information about intoxication and the state of the immune response in sick animals. Moreover, calculated leukocyte indexes can become an alternative to complex and expen-sive studies to determine the immunogram, cytokine content, and a number of other bio-chemical parameters. In this paper, we con-sidered the nature of changes in immunologi-cal indicators in piglets under technological stress as a result of weaning and regrouping, and we used calculated leukocyt

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Mahmood, Majid M., Ahmed N. Al-ani, and Basil R. Razook. "Hematological Picture of Rabbits Immunized with Pseudomonas aeruginosa." Iraqi Journal of Veterinary Medicine 44, (E0) (2020): 64–68. http://dx.doi.org/10.30539/ijvm.v44i(e0).1023.

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The current study was established to find out the role of immunization of Pseudomonas aeruginosa-whole sonicated antigen in adult white fur domestic rabbits. To achieve this goal, fifteen rabbits were allocated into 3 groups, the first group was immunized with P. aeruginosa–whole sonicated antigen and challenged with viable pathogenic P. aeruginosa; the second group (control negative) was treated with phosphate buffer saline and the third group was injected with viable pathogenic P. aeruginosa (control positive). The results demonstrated increasing levels of the measured parameters blood pictu

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Hefner, Jochen, and Herbert Csef. "Neuere Ergebnisse der Psychoneuroimmunologie (PNI) zum Verlauf von Krebserkrankungen." Zeitschrift für Medizinische Psychologie 16, no. 4 (2007): 149–57. https://doi.org/10.3233/zmp-2007-16_4_02.

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Recent psychoneuroimmunlogical studies inspire the discussion about the influence of mental strain on the course of cancer. Adverse effects are documented for solid and hematological tumors. The underlying mechanisms are only partially understood. Most studies investigated natural killer cells as most relevant immunological factors. But inconsistent results have led the focus towards direct neurohumoral mechanisms. Similar to basic oncological research, interactions with the tumor microenvironment are being examined. Current results permit only speculations about the interacting mechanisms. Fu

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Abdrakhmanova, Elena R., Natalya V. Vlasova, Lyaylya M. Masyagutova, Liliya G. Gizatullina, Linara A. Rafikova, and Guzel M. Chudnovets. "Comprehensive analysis of the laboratory examination results of patients with an established bronchial asthma diagnosis." RUDN Journal of Medicine 25, no. 3 (2021): 209–18. http://dx.doi.org/10.22363/2313-0245-2021-25-3-209-218.

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Relevance. Bronchial asthma is a serious medical and social problem. To confirm the diagnosis, it is necessary to assess the allergic status, to determine the biological markers of the disease. Of particular relevance is a comprehensive analysis of the results of laboratory examination of patients, including data from hematological, immunological, microbiological studies. Aim. To study some laboratory parameters (hematological, immunological and microbiological), the changes of which are most typical for patients with an established diagnosis of bronchial asthma. Matherials and Methods . A cli

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Yang, Fan, Yang LEI, Qinlong Zheng, et al. "Interleukin-7 Receptor Gene Heterozygous Mutations in Recipients Significantly Increase Acute Graft-Versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation." Blood 136, Supplement 1 (2020): 37–38. http://dx.doi.org/10.1182/blood-2020-140164.

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Acute graft-versus-host disease (aGVHD) is one of major complications of allogeneic hematopoietic stem cell transplantation (allo-HSCT). Genetic polymorphisms of interleukin-7 receptor (IL-7R) have an impact on transplant-related mortality (Z Shamim et al. BMT 2006). Our previous studies indicated that hematological and immunological hereditary predisposition genes have potential influence on major complications of allo-HSCT in patients with hematological malignancies (unpublished data). In present study, the influence of hematological and immunological hereditary predisposition genes on aGVHD

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Hashem, Mohamed, Shefaa El-Mandrawy, Mohamed El-Diasty, and Asmaa Zidan. "Hematological, Biochemical and Immunological Studies on Brucellosis in Cows and Ewes in Dakahlia and Damietta Governorates, Egypt." Zagazig Veterinary Journal 48, no. 1 (2020): 23–35. http://dx.doi.org/10.21608/zvjz.2019.15557.1070.

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Zian, Zeineb, Mouna Maamar, Mohamed El Aouni, et al. "Immunological and Clinical Characteristics of Systemic Lupus Erythematosus: A Series from Morocco." BioMed Research International 2018 (September 30, 2018): 1–5. http://dx.doi.org/10.1155/2018/3139404.

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Systemic Lupus Erythematosus (SLE) is a complex autoimmune disease with a high female predominance. To date, studies about SLE in Morocco are few. This retrospective study describes the clinical and immunological features in a series of 50 SLE Moroccan patients in University Hospital Center of Rabat, Morocco, between December 2011 and December 2013. All patients were screened for antinuclear antibodies (ANA) and anti-DNA antibodies by indirect immunofluorescence, followed by identification of anti-extractable nuclear antigen antibodies by ELISA. The female to male ratio was 6.1:1. Mean age was

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Visoná, Kirsten, Fulgencio Baez, Lizeth Taylor, et al. "Impact of Hepatitis B and Hepatitis C Virus Infections in a Hematology-Oncology Unit at a Children's Hospital in Nicaragua, 1997 to 1999." Clinical and Vaccine Immunology 9, no. 3 (2002): 622–26. http://dx.doi.org/10.1128/cdli.9.3.622-626.2002.

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ABSTRACT The risk of acquiring both hepatitis B virus (HBV) and hepatitis C virus (HCV) infections in patients with hematological-oncological disorders has been documented. However, the impact and risk factors for such infections from different geographical areas vary, and the use of both immunological and molecular assays to determine HCV infections has been our approach. Children from a hematology-oncology unit (HOU) in Nicaragua were studied for both HBV and HCV serological markers; studies for the latter used both immunological (anti-HCV) and molecular (HCV RNA) assays. The children from t

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Medina-Torrez, E. A., M. Vela-Amieva, L. Galindo-Campos, et al. "Abnormalities in subsets of B and T cells in Mexican patients with inborn errors of propionate metabolism: observations from a single-center case series." Allergologia et Immunopathologia 49, no. 1 (2021): 101–6. http://dx.doi.org/10.15586/aei.v49i1.27.

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Background: Propionate inborn errors of metabolism (PIEM), including propionic (PA) and methylmalonic (MMA) acidemias, are inherited metabolic diseases characterized by toxic accumulation of propionic, 3-hydroxypropionic, methylcitric, and methylmalonic organic acids in biological fluids, causing recurrent acute metabolic acidosis events and encephalopathy, which can lead to fatal outcomes if managed inadequately. PIEM patients can develop hematological abnormalities and immunodeficiency, either as part of the initial clinical presentation or as chronic complications. The origin and characteri

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Medina-Torrez, E. A., M. Vela-Amieva, L. Galindo-Campos, et al. "Abnormalities in subsets of B and T cells in Mexican patients with inborn errors of propionate metabolism: observations from a single-center case series." Allergologia et Immunopathologia 49, no. 1 (2021): 101–6. http://dx.doi.org/10.15586/aei.v49i1.27.

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Background: Propionate inborn errors of metabolism (PIEM), including propionic (PA) and methylmalonic (MMA) acidemias, are inherited metabolic diseases characterized by toxic accumulation of propionic, 3-hydroxypropionic, methylcitric, and methylmalonic organic acids in biological fluids, causing recurrent acute metabolic acidosis events and encephalopathy, which can lead to fatal outcomes if managed inadequately. PIEM patients can develop hematological abnormalities and immunodeficiency, either as part of the initial clinical presentation or as chronic complications. The origin and characteri

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Фатеева, Екатерина, Ekaterina Fateeva, Евгений Корнюшенков, et al. "Experience of the safety evaluation of the cellular immunotherapy application on basis LAC for canine oncological diseases treatment." Russian veterinary journal 2019, no. 3 (2019): 13–23. http://dx.doi.org/10.32416/article_5d10c406226e76.51462383.

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Purpose of research. To evaluate the effect of LAC (mononuclear blood leukocytes activated by IL-2 ex vivo) suspension infusion on clinical, biochemical, hematological and immunological characteristics of a healthy Beagle dog to assess the safety of the product’s application.  Materials and methods. The research object is a 6-year Beagle dog male. The LAC suspension in Hank’s solution has been infused intravenously with a low rate of administration; the dose used was 25 m cells in 5 ml. An autologous culture of LAC has been generated from canine blood, evaluated by morphology, phen

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Egorova, V. I., and I. V. Volkova. "Dynamics of integral hematological indices of fish in chronic intoxication." Fisheries, no. 1 (February 26, 2025): 81–88. https://doi.org/10.36038/0131-6184-2024-1-81-88.

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Today, laboratory practice has a rich arsenal of methods for dynamic control over the course of pathological processes in the body of fish. Quantitative indicators of blood leukocytes and, especially, indicators of its leukocyte formula are important re-search methods in the diagnosis of a wide variety of pathological conditions. To objectively assess these results, a number of indicators have now been proposed that determine the course of pathological processes in the body, but these indicators are not used in real fisheries science and aquaculture.The purpose of our study was to study the dy

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Gudina, Ayantu, Moges Wordofa, and Fekadu Urgessa. "Immuno-hematological parameters among adult HIV patients before and after initiation of Dolutegravir based antiretroviral therapy, Addis Ababa, Ethiopia." PLOS ONE 19, no. 10 (2024): e0310239. http://dx.doi.org/10.1371/journal.pone.0310239.

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Background Immuno-hematological abnormalities are common among HIV infected individuals as well as patients with highly active antiretroviral therapy (HAART). However, the immuno-hematological outcome of Dolutegravir based antiretroviral therapy (ART) usage is not well investigated. Objectives To assess hematological and immunological parameters among adult HIV patients before and after initiation of Dolutegravir based ART regimen at St. Peter Specialized Hospital, Addis Ababa, Ethiopia. Methods A cross-sectional study was conducted from May to July 2021 at St. Peter Specialized Hospital among

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Ferreira, Milene S., Lívia C. Martins, Karla F. L. de Melo, et al. "Experimental Yellow Fever in the Squirrel Monkey (Saimiri spp.): Hematological, Biochemical, and Immunological Findings." Viruses 15, no. 3 (2023): 613. http://dx.doi.org/10.3390/v15030613.

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Between 2016 and 2018, Brazil experienced the largest sylvatic epidemic of yellow fever virus (YFV). Despite to the magnitude and rapid spread of the epidemic, little is known about YFV dispersion. The study evaluated whether the squirrel monkey is a good model for yellow fever (YF) studies. Methods: Ten animals were infected with 1 × 106 PFU/mL of YFV, with one negative control. Blood samples were collected daily during the first 7 days and at 10, 20 and 30 days post infection (dpi) for detection of viral load and cytokines by RT-qPCR; measurements of AST, ALT, urea and creatinine were taken;

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Kozyr, V. S., P. P. Antonenko, N. I. Suslova, and R. V. Mylostyvyi. "Results of studies of the influence of phytopreparations on cows and calfs." E3S Web of Conferences 282 (2021): 04003. http://dx.doi.org/10.1051/e3sconf/202128204003.

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Purpose. To establish the influence of the “Phytochol”, “Phytopunk” and “Gastroacide” phytopreparations developed by the authors on the reproductive function of cows, resistance and safety for calves. Methods. Biological, biochemical, hematological, immunological, analytical, biometric, zootechnical. Results. It has been established that in homeopathic doses, the studied drugs are non-toxic, have a wide range of pharmacological effects and contain biologically active substances that have strengthening, tonic properties, metabolism normalizing in the “cow-calf” biochemical system. Conclusions.

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Burlakov, Sergei V., Anna V. Burlakova, Andrei V. Kapustin, Pavel N. Shastin, and Aleksei I. Laishevtsev. "Hematological and immunological parameters of the blood of turkeys vaccinated against salmonellosis." Veterinariya, Zootekhniya i Biotekhnologiya 1, no. 10 (2021): 19–27. http://dx.doi.org/10.36871/vet.zoo.bio.202110003.

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The effect of vaccination against salmonellosis on the morphological composition of the blood of broiler turkeys was studied. The dynamics of seroconversion of antibodies to S. enteritidis, S. typhimurium and S. infantis were analysed. The results obtained, which demonstrate an increase in hematocrit, hemoglobin level, average hemoglobin concentration in erythrocyte (MCHC), average erythrocyte volume and average hemoglobin content in erythrocyte (MCH), indicate an increase and optimization of key quantitative indicators of blood cells of a group of birds, two times immunized against salmonello

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Zhandalgarova, Adelya Dzumaniyashevna, Anna Alexandrovna BAKHAREVA, and Yulia Nikolaevna Grozesku. "Probiotic drug effect evaluation on the enterosorbent “Florin forte” on the physiological and immunological state of bester." Vestnik of Astrakhan State Technical University. Series: Fishing industry 2023, no. 4 (2023): 42–47. http://dx.doi.org/10.24143/2073-5529-2023-4-42-47.

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Assessment of the physiological and immunological status of fish is an urgent problem of modern aquaculture. One of the methods of such assessment is based on hematological and biochemical studies. Blood is the most sensitive and informative indicator of changes occurring in the body of fish. It reacts quickly and acutely to the effects of various adverse environmental factors and can serve as one of the early indicators of a violation of the functional state of fish. The study  of the effect of a probiotic drug on the enterosorbent “Florin forte” on hematological and biochemical blood p

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J., Vimalin Hena, and S. Sudha S. "Immunotoxicological studies of Staphylococcin of CA-MRSA." Journal of Advanced Laboratory Research in Biology 1, no. 2 (2010): 98–100. https://doi.org/10.5281/zenodo.1318936.

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Methicillin-resistant <em>Staphylococcus aureus</em> isolated from the nares of school going children (CA-MRSA) has been found to produce bacteriocin like inhibitory substance tentatively termed staphylococcin<em>.</em> It has a broad activity spectrum against many Gram positive bacteria including <em>Staphylococcus aureus</em> which suggests that the protein molecule can be used as an alternative for antibiotics. In this regard, the bacteriocin was studied for its immunological and toxicological properties in experimental mice. The antigenicity/immunogenicity of bacte

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Cherif, Honar, Magnus Bjorkholm, Mats Kalin, Helle B. Konradsen, and Ola Landgren. "Antibody Response to Pneumococcal Polysaccharide Vaccination Predicts Pneumococcal Disease in Splenectomized Patients with Hematological Diseases." Blood 104, no. 11 (2004): 1335. http://dx.doi.org/10.1182/blood.v104.11.1335.1335.

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Abstract Patients with hematological diseases undergoing diagnostic or therapeutic splenectomy are at increased risk of acquiring fulminant pneumococcal infections. Vaccination is a straightforward option in reducing these infections. Certain patient subgroups showing inadequate immunological response to pneumococcal vaccination may be candidates for alternative prophylactic measures. We prospectively studied the antibody response to vaccination with 23-valent pneumococcal capsular polysaccharide vaccine (Pneumovax N) in splenectomized patients with hematological disorders in relation to clini

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LOMBARDI, Valter R. M., Lucia FERNANDEZ-NOVOA, Ignacio ETCHEVERRIA, Silvia SEOANE, and Ramon CACABELOS. "Studies on immunological, biochemical, hematological and growth regulation by Scomber scombrus fish protein extract supplementation in young pigs." Animal Science Journal 76, no. 2 (2005): 159–70. http://dx.doi.org/10.1111/j.1740-0929.2005.00252.x.

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Roy, Bedanta, Juliet Othieno, and Nabeeha Fauzee. "VEXAS syndrome: A review on clinical manifestations." Journal of Biomedical Sciences 10, no. 2 (2023): 40–48. http://dx.doi.org/10.3126/jbs.v10i2.61358.

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Background: VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome is a recently identified progressive, adult-onset, inflammatory disorder. Somatic mutations in the Ubiquitin-like modifier activating enzyme 1 (UBA1) gene at methionine-41 (p. Met41) were found in the patients. Clinical presentations are not limited to hematological and immunological systems; all organ systems are affected by VEXAS syndrome. The aim of this review is to summarise the scientific evidence accrued from the research studies on VEXAS syndrome, highlighting the clinical features and involvements of

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Rehman, Hasibur, Al Thbiani Aziz, Shalini Saggu, Adam L. VanWert, Nahla Zidan, and Sundeep Saggu. "Additive toxic effect of deltamethrin and cadmium on hepatic, hematological, and immunological parameters in mice." Toxicology and Industrial Health 33, no. 6 (2017): 495–502. http://dx.doi.org/10.1177/0748233716684710.

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Exposure to natural and man-made environmental toxins concurrently can pose a greater threat to multiple organs. In the present work, we investigated interactions between deltamethrin (DM) and cadmium (Cd), whose mechanisms of action in humans are poorly understood. Albino mice were randomly divided into four groups, each containing six mice: saline as control, DM-treated, cadmium chloride (CdCl2)-treated, and CdCl2 plus DM treated. After 2 weeks of treatment biochemical and hematological effects, total leukocyte count (TLC), differential leukocyte count, humoral-mediated immune responses, and

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Zucon, Isabela Soriani. "INOVAÇÕES BIOTECNOLÓGICAS: O PAPEL DAS CÉLULAS – TRONCO E DA ENGENHARIA GENÉTICA NO TRANSPLANTE DE MEDULA ÓSSEA." Revista ft 28, no. 140 (2024): 49–50. https://doi.org/10.69849/revistaft/pa10202411301049.

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This study explores the impact of biotechnological and artificial intelligence advancements on Bone Marrow Transplantation (BMT), focusing on treating hematological and immunological diseases. It reviews the historical evolution of BMT, to contemporary breakthroughs like CRISPR-Cas9 gene editing, which corrects genetic mutations and enhances clinical outcomes. Based on a literature review the research highlights the critical role of HLA compatibility and hematopoietic stem cells while emphasizing artificial intelligence’s potential to personalize treatments and predict complications. Despite t

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Verizhnikova, Zhanna, Anastasia Avdeeva, Valeriia Rybakova, and Tatiana Popkova. "THE RELATIONSHIP OF THE LEVEL OF ANTINUCLEAR ANTIBODIES WITH CLINICAL AND IMMUNOLOGICAL SUBTYPES OF SYSTEMIC LUPUS ERYTHEMATOSUS." Journal of Rheumatology 52, Suppl 1 (2025): 224.1–224. https://doi.org/10.3899/jrheum.2025-0390.pv232.

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PV232 / #222Poster Topic:AS23 - SLE-Diagnosis, Manifestations, & OutcomesBackground/PurposeAntinuclear antibodies (ANA) are a specific marker related to the classification criteria of systemic lupus erythematosus (SLE). The purpose of our study was evaluating ANA levels in relation to clinical and immunological subtypes of SLE.MethodsSera from 94 patients (pts) diagnosed with SLE (SLICC criteria, 2012), including 80 women and 14 men, age (Median, [25th;75th percentile] 31 [27;47] years, disease duration 84.0 [24.0;168.0] months were studied. The following clinical manifestations were inves

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Fernández-Lázaro, Diego, Cesar I. Fernandez-Lazaro, Jesús Seco-Calvo, Evelina Garrosa, David P. Adams, and Juan Mielgo-Ayuso. "Effects of Tribulus terrestris L. on Sport and Health Biomarkers in Physically Active Adult Males: A Systematic Review." International Journal of Environmental Research and Public Health 19, no. 15 (2022): 9533. http://dx.doi.org/10.3390/ijerph19159533.

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Tribulus terrestris L. (TT) is a plant used in traditional Chinese medicine, Ayurvedic medicine, and sports nutrition to improve health and performance. However, no conclusive evidence exists about the potential beneficial effects of TT on sport and health biomarkers in physically active adults. Based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, and the modified McMaster Critical Review Form for methodological quality assessment, we systematically reviewed studies indexed in Web of Science, Scopus, and PubMed, to assess the effects of TT on imm

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Li, Zhihui, Yongqiang Zhao, Yanzhi Song, et al. "Influence of Inherited and Acquired Hematological and Immunological Gene Variants on the Outcomes of Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Hematological Malignancies." Blood 136, Supplement 1 (2020): 46–47. http://dx.doi.org/10.1182/blood-2020-139220.

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Chromosome abnormalities and gene variants are important factors in prognosis of the patients with hematological malignancies. Our previous study showed that some germline gene mutations-related to hematological and immunological disorders may have negative impact on the complications of allogeneic hematopoietic stem cell transplantation (allo-HSCT). In current study, the influence of both hematological and immunological hereditary predisposition gene variants and tumor gene variants on the outcomes of allo-HSCT in patients with hematological malignancies was studied. Between January 2018 and

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Ige, Serah Funke, Adenike Mariam Adeniyi, and Sakirat Deebby Ibrahim. "Hematological and Immunological Characterizations of Experimental Ulcerative Colitis Rats: The Impact of Alcohol Consumption Pattern." International Journal of Biomedical Science 17, no. 2 (2021): 6–14. http://dx.doi.org/10.59566/ijbs.2021.17006.

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BACKGROUND: Studies have documented the contributions of alcohol to ulcerative colitis (UC) development. The present study sought to determine the specific pattern of hematological and immunological indices in experimental ulcerative colitis rats exposed to different alcohol intervention schedules. METHODS: 28 female Wistar rats weighing between 150-200 g were randomly divided into control, non-alcohol colitis (NAC), low-frequency alcohol colitis (LAC) and high-frequency alcohol colitis (HAC) groups. Experimental UC was induced through a single intra-colic instillation of 1 ml/100g of 7% aceti

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Omelian, L. P., and N. A. Matsehora. "Hematological and biochemical features with tuberculosis and bacterial lymphadenitis in children." Tuberculosis, Lung Diseases, HIV Infection, no. 3 (October 1, 2021): 15–21. http://dx.doi.org/10.30978/tb2021-3-15.

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Objective — to improve approaches to differential diagnosis of lymphadenitis by identifying features of hematological and biochemical parameters of blood of children with nonspecific bacterial and specific tuberculous lymphadenitis. Materials and methods. Under our supervision were 45 children aged 1 to 5 years with an increase in lymph nodes (LN), who were treated in the surgical department of the Odessa Regional Children’s Clinical Hospital for the period from 2017 to 2018. Patients were assessed for general condition and affected lymph node lesions, as well as blood sampling for gener

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Nehete, Pramod N., Bharti P. Nehete, Akash G. Patel, Sriram Chitta, Henrieta Scholtzova, and Lawrence E. Williams. "Short-Term Relocation Stress-Induced Hematological and Immunological Changes in Saimiri boliviensis boliviensis." Journal of Immunology Research 2021 (November 8, 2021): 1–12. http://dx.doi.org/10.1155/2021/5318590.

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Nonhuman primates are frequently transported to a new location or temporarily relocated within their colony. Both transportation and relocation expose animals to new environments, causing them to undergo a stress response (before adapting). In our NHP colony, the mentioned situations are not infrequent for many reasons, including maintenance. The objective of this study was to determine whether abrupt changes consisting of relocation, housing, separation, and grouping could influence hematological and immunological parameters and thereby functional activity. The current study used squirrel mon

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Ubeid, Muhsin H., Ameena S. M. Juma, Shakir M. Al-Awqati, Tanya S. Salih, and Muhamed A. Abbas. "Vitamin D levels in Coronavirus-infected Individuals and its Correlation with Certain Hematological Markers." Cihan University-Erbil Scientific Journal 8, no. 2 (2024): 31–35. http://dx.doi.org/10.24086/cuesj.v8n2y2024.pp31-35.

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The world and nearly all our health care system were confronted by a significant threat which was declared by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Determining the SARS-CoV-2 or COVID-19’s prognostic and modifiable measures surely would largely contribute to outcome improving despite the deficiency of causative therapy that affected nearly 200 million people, 3.5 million fatal incidences, and it is still airborne. The research in hand examined probable relations between the levels of vitamin D (VitD) and immunological markers. Hence, a sample of 200 lecturers and st

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Caisa Chalan, Jessenia Lizbeth, and Fabiola Beatriz Chasillacta Amores. "Hematological profile in malnourished children and adolescents." Sapienza: International Journal of Interdisciplinary Studies 5, no. 4 (2024): e24073. https://doi.org/10.51798/sijis.v5i4.866.

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Introduction: The hematological profile is a key diagnostic tool to assess the effects of malnutrition, revealing common abnormalities such as anemia, leukopenia, thrombocytopenia, and hypoalbuminemia. These abnormalities indicate nutritional deficiencies and related health problems such as iron deficiency anemia due to lack of iron, immune system weakness, and electrolyte imbalances. Adequate treatment based on correcting these deficiencies and continuous monitoring is essential to improve this vulnerable population's health status and prognosis. Objective: To determine the hematological prof

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Niedźwiecki, M., O. Budziło, E. Adamkiewicz-Drożyńska, et al. "CD4+CD25highCD127low/-FoxP3+ Regulatory T-Cell Population in Acute Leukemias: A Review of the Literature." Journal of Immunology Research 2019 (March 3, 2019): 1–15. http://dx.doi.org/10.1155/2019/2816498.

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Regulatory T-cells (Tregs) are a very important subtype of lymphocytes when it comes to self-control in the human immunological system. Tregs are decisive not only in the protection against destruction of own tissues by autoimmune immunocompetent cells but also in the immunological answer to developing cancers. On the other hand, Tregs could be responsible for the progression of acute and chronic leukemias. In our study, we review publications available in the PUMED database concerning acute leukemia, with a particular emphasis on child’s leukemias. The percentage of regulatory T-lymphocytes i

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Ahmed, Asfa, Muhammad Omer Sultan, Muhammad Inam Khan, and Alisha Ahmed. "Clinical and Immunological Manifestations of Patients Presenting With Systemic Lupus Erythematosus At Tertiary Care Hospital, Karachi." Biological and Clinical Sciences Research Journal 6, no. 1 (2025): 83–87. https://doi.org/10.54112/bcsrj.v6i1.1545.

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Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that affects multiple organ systems, with a high prevalence among young women. It presents various clinical and immunological manifestations, including arthritis, skin rashes, oral ulcers, hematological abnormalities, and neurological involvement. Early diagnosis and management depend on recognising key clinical symptoms and autoantibody profiles. Understanding SLE patterns in different populations is essential for improving diagnostic accuracy, treatment strategies, and patient outcomes. Objective: This study aims to assess th

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Cherny, N. V., та V. V. Kulak. "РЕЗИСТЕНТНІСТЬ І ПРОДУКТИВНІСТЬ КРОЛІВ ПРИ ВИКОРИСТАННІ ПРОБІОТИКА «ЕВІТАЛІЯ» В УМОВАХ НОРМАТИВНОГО МІКРОКЛІМАТУ". Scientific Messenger of LNU of Veterinary Medicine and Biotechnology 18, № 2(66) (2016): 192–97. http://dx.doi.org/10.15421/nvlvet6639.

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The influence of probiotic «Evitaliya» hematological, biochemical and immunological parameters of the giant white rabbits in terms of regulatory climate. The studies were performed on young rabbits from birth until 120 days of age, two groups of animals. Experienced groups asked the drug twice a day for 25 ml per head from birth to 30 days of age, and then 50 ml on the head (from 31 – to 90– day age). To assess the effect of the probiotic on the body of the rabbit used hygienic methods of research (definition of temperature and humidity, bacterial obremenjenosti air, light); clinical (body tem

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Chornyi, M. V. "Stress state and immunological status of young pigs." Veterinary Medicine: inter-departmental subject scientific collection, no. 105 (August 7, 2019): 95–98. http://dx.doi.org/10.36016/vm-2019-105-19.

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The paper presents the results of studies on the effect of regrouping of piglets at different ages on the resistance of their organisms, immunological status, productive qualities and safety of young pigs. The work was performed at “Stas” LLC on large white breed pigs and their crossbreeds. For the experiment, three groups of piglets were formed from suckling sows — analogues. In the experiment 60 animals from birth up to two months of age were used, 20 animals in each experimental group. The control group of piglets was raised from birth up to 60 days of age in nests, and then they were moved

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CHAKRABARTI, SUPARNO, Snigdha Banerjee, Mahak Agarwal, Gitali Bhagawati, Nilanjan Saha, and SARITA JAISWAL. "COVID-19 Induces Prolonged Immunological Exhaustion Leading to Relapse of Hematological Malignancies Except in Hematopoietic Cell Transplant Recipients." Mediterranean Journal of Hematology and Infectious Diseases 17, no. 1 (2025): e2025042. https://doi.org/10.4084/mjhid.2025.042.

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We studied the impact of COVID-19 on relapse in patients with hematological malignancies who had achieved complete remission (CR) and were either treatment-free or maintained on uninterrupted therapy over a 24-month period, excluding patients who relapsed or succumbed to the infection within 30 days.

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Paganelli, Roberto, Michela Di Lizia, Marika D’Urbano, et al. "Insights from a Case of Good’s Syndrome (Immunodeficiency with Thymoma)." Biomedicines 11, no. 6 (2023): 1605. http://dx.doi.org/10.3390/biomedicines11061605.

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Immunodeficiency with thymoma was described by R.A. Good in 1954 and is also named after him. The syndrome is characterized by hypogammaglobulinemia associated with thymoma and recurrent infections, bacterial but also viral, fungal and parasitic. Autoimmune diseases, mainly pure red cell aplasia, other hematological disorders and erosive lichen planus are a common finding. We describe here a typical case exhibiting all these clinical features and report a detailed immunophenotypic assessment, as well as the positivity for autoantibodies against three cytokines (IFN-alpha, IL-6 and GM-CSF), whi

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