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Journal articles on the topic 'Immunological aspects of Medical parasitology'

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1

Mueller-Loebnitz, Christoph, Helmut Ostermann, Anke Franzke, Juergen Loeffler, Lutz Uharek, Max Topp, and Hermann Einsele. "Immunological Aspects ofCandidaandAspergillusSystemic Fungal Infections." Interdisciplinary Perspectives on Infectious Diseases 2013 (2013): 1–7. http://dx.doi.org/10.1155/2013/102934.

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Patients with allogeneic stem cell transplantation (SCT) have a high risk of invasive fungal infections (IFIs) even after neutrophil regeneration. Immunological aspects might play a very important role in the IFI development in these patients. Some data are available supporting the identification of high-risk patients with IFI for example patients receiving stem cells from TLR4 haplotype S4 positive donors. Key defense mechanisms against IFI include the activation of neutrophils, the phagocytosis of germinating conidia by dendritic cells, and the fight of the cells of the innate immunity such as monocytes and natural killer cells against germlings and hyphae. Furthermore, immunosuppressive drugs interact with immune effector cells influencing the specific fungal immune defense and antimycotic drugs might interact with immune response. Based on the current knowledge on immunological mechanism inAspergillus fumigatus, the first approaches of an immunotherapy using human T cells are in development. This might be an option for the future of aspergillosis patients having a poor prognosis with conventional treatment.
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2

Araújo, Marcelo Grossi, Denise Utsch Gonçalves, Vandack Nobre, João Gabriel Ramos Ribas, Anna Bárbara de Freitas Carneiro-Proietti, José Roberto Lambertucci, and Antonio Carlos Martins Guedes. "HTLV-1 associated myelopathy diagnosed during lepromatous leprosy reaction treatment: a case report." Revista da Sociedade Brasileira de Medicina Tropical 43, no. 4 (August 2010): 465–66. http://dx.doi.org/10.1590/s0037-86822010000400027.

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Leprosy and human T cell lymphotropic virus type 1 infection are prevalent in Brazil. Coinfection by Mycobacterium leprae and HTLV-1 is reviewed and a case is reported. A 59 year-old woman was followed and HTLV-1 associated myelopathy was diagnosed during leprosy treatment. The clinical and neurological aspects of this unusual association were initially reviewed. Immunological markers and the possible prognoses due to the association of the diseases were discussed. The unexpected association of leprosy and HTLV-1 associated myelopathy may occur in endemic areas and causes difficulties in determining the correct diagnosis and adequate management of the neurological manifestations.
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3

Gonçalves, Elenice Messias do Nascimento, Iaiko Horroiva Uemura, Vera Lúcia Pagliusi Castilho, and Carlos Eduardo Pereira Corbett. "Retrospective study of the occurrence of Cyclospora cayetanensis at Clinical Hospital of the University of São Paulo Medical School, SP." Revista da Sociedade Brasileira de Medicina Tropical 38, no. 4 (August 2005): 326–30. http://dx.doi.org/10.1590/s0037-86822005000400009.

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Cyclospora cayetanensis causes watery diarrhea in tropical countries, among travelers and after ingestion of contaminated water and food. Very little is known about its epidemiology, pathogenic aspects and reservoirs. In Brazil, its prevalence is unknown and to date there have been reports of three outbreaks. We report here a retrospective study of 5,015 stool samples from 4,869 patients attended at Clinical Hospital of the University of São Paulo Medical School, SP, Brazil between April 1996 and January 2002, with 14 cases of Cyclospora cayetanensis being detected there was a prevalence of 0.3%. Of the 14 infected patients, the mean age was 38 years and 71.4% were female. Ten patients presented symptoms; six presented levels of immunological markers and five patients were immunodeficient.
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4

MOUNTFORD, A. P. "Immunological aspects of schistosomiasis." Parasite Immunology 27, no. 7-8 (July 2005): 243–46. http://dx.doi.org/10.1111/j.1365-3024.2005.00798.x.

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5

Croft, S. L. "Molecular and immunological aspects of parasitism." Parasitology Today 8, no. 3 (March 1992): 107. http://dx.doi.org/10.1016/0169-4758(92)90256-2.

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6

Teplen’kiy, M. P., M. V. Chepeleva, and E. I. Kuznetsova. "PERTHES DISEASE: IMMUNOLOGICAL ASPECTS." Russian Clinical Laboratory Diagnostics 65, no. 4 (April 15, 2020): 239–43. http://dx.doi.org/10.18821/0869-2084-2020-65-4-239-243.

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Considering a stage of the pathological process patients (boys at the age of 8-12 years) were divided into two (2) groups. Group I included 14 patients with the fragmentation stage (Perthes disease Stage II). Group 2 included 15 children with Perthes disease Stage III (the stage of re-ossification). Perthes disease regardless of the stage of the disease was characterized by the increase in oxygen-dependent and lysosomal phagocytic activity of neutrophils, the increase in the number of early extracellular traps, as well as by increased concentrations of pro-inflammatory cytokines (IL-1β and TNFa), IgE, decreased concentrations of IL-18. The fragmentation stage was characterized by moderate activation of cellular immunity with a prevailing increase in the number of T-lymphocytes with early activation markers (CD25). At the re-ossification stage the predominance of T-lymphocytes was observed with late activation markers (HLADR), being accompanied by moderate activation of humoral immunity (increased concentrations of class A and G serum immunoglobulins). The obtained data can be used as additional criteria for clarifying Perthes disease stage, predicting osteonecrosis development when making decision of the feasibility of performing reconstructive surgeries on the joint.
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7

Holder, Tony. "Modern parasite biology: Cellular, immunological and molecular aspects." Parasitology Today 7, no. 10 (January 1991): 292. http://dx.doi.org/10.1016/0169-4758(91)90101-s.

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8

Overeem, Sebastiaan, John Logan Black, and Gert Jan Lammers. "Narcolepsy: Immunological aspects." Sleep Medicine Reviews 12, no. 2 (April 2008): 95–107. http://dx.doi.org/10.1016/j.smrv.2007.07.010.

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9

Sarno, Euzenir Nunes. "The immunological aspects of leprosy." Memórias do Instituto Oswaldo Cruz 82, suppl 2 (1987): 159–62. http://dx.doi.org/10.1590/s0074-02761987000600024.

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10

Corrigan, Chris J. "Immunological Aspects of Asthma." Clinical Immunotherapeutics 1, no. 1 (January 1994): 31–42. http://dx.doi.org/10.1007/bf03258489.

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11

Bárány, Peter, and Ingela Fehrman-Ekholm. "Immunological Aspects of Haemodialysis." Clinical Immunotherapeutics 1, no. 6 (June 1994): 469–80. http://dx.doi.org/10.1007/bf03259039.

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12

Damian, Raymond T. "Immunological aspects of host-schistosome relationships." Memórias do Instituto Oswaldo Cruz 82, suppl 4 (1987): 13–16. http://dx.doi.org/10.1590/s0074-02761987000800004.

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13

DeGraba, Thomas J. "Immunological Aspects of Acute Stroke." BioDrugs 13, no. 1 (January 2000): 1–8. http://dx.doi.org/10.2165/00063030-200013010-00001.

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14

Shalit, I. "Immunological aspects of new quinolones." European Journal of Clinical Microbiology & Infectious Diseases 10, no. 4 (April 1991): 262–66. http://dx.doi.org/10.1007/bf01966999.

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15

Deepe, G. S., and W. E. Bullock. "Immunological aspects of fungal pathogenesis." European Journal of Clinical Microbiology & Infectious Diseases 9, no. 8 (August 1990): 567–79. http://dx.doi.org/10.1007/bf01967211.

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16

Vass, Emily, and Anthony J. Nappi. "DEVELOPMENTAL AND IMMUNOLOGICAL ASPECTS OFDROSOPHILA–PARASITOID RELATIONSHIPS." Journal of Parasitology 86, no. 6 (December 2000): 1259–70. http://dx.doi.org/10.1645/0022-3395(2000)086[1259:daiaod]2.0.co;2.

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17

Franca-Bot, A. C., R. P. Lopes, J. L. Franca ., and M. A. Gomes. "Advances in Amoebiasis Research Emphasizing Immunological and Oxidative Aspects." Research Journal of Parasitology 6, no. 1 (January 1, 2011): 1–17. http://dx.doi.org/10.3923/jp.2011.1.17.

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18

Stoll, Guido, Sebastian Jander, Mario Siebler, and Michael Schroeter. "Immunological Aspects of Ischaemic Stroke." CNS Drugs 14, no. 3 (September 2000): 213–28. http://dx.doi.org/10.2165/00023210-200014030-00004.

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19

Conway, Brian, and Francisco J. Diaz-Mitoma. "Virological and Immunological Aspects of AIDS Pathogenesis." Canadian Journal of Infectious Diseases 5, suppl e (1994): 13E—18E. http://dx.doi.org/10.1155/1994/157142.

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The most common and serious problem associated with long term antiretroviral therapy is waning efficacy over time. To date. a number of studies has suggested an association between drug resistance and clinical deterioration. However. a precise causal relationship has yet to be demonstrated. In a large American clinical trial. resistance to zidovudine (ZDV) was predictive of subsequent disease progression if this therapy was continued. Surprisingly. this was also predictive of deterioration if therapy was changed to didanosine (ddl). This suggests that other factors (perhaps virological and immunological) which may be present in addition to resistance. were as important (if not more so) in predicting clinical outcomes. It is likely that viral load. resistance. viral phenotype and alterations in immune function interact in this regard. Proper· studies may allow us to determine a “threshold” for a composite virological and immunological parameter beyond which disease progression will occur. As more antiretroviral agents become available. we will be in a position to intervene to “improve” laboratory markers and monitor them prospectively. potentially to maintain clinical latency for an indefinite period of time. In the authors' laboratories, a quantitative polymerase chain reaction assay for the evaluation of circulating proviral load has been developed. In an initial study of 70 patients. proviral load/ 106CD4 cells was clearly associated with the severity of immune disease. with up to 9.6% of cells being infected in subjects with CD4 cell counts below 200/µL. However. large variability in proviral load among individuals with comparable or dissimilar CD4 cell counts precludes the use of this measurement as an individual marker of the severity of immune disease. More recent work evaluated the combined use of proviral load (expressed as a dichotomous variable based on values above or below one copy/a03CD4 cells) and resistance in a prospective fashion. In five patients with high proviral loads and isolates resistant to their current therapy. a mean decrease of 72 CD4 cells/µL was observed over 12 months of observation. In contrast. in six patients with low proviral loads and sensitive isolates. there was a mean increase of 43 CD4 cells/µL. It appears that virological markers are associated with immune disease progression in this small cohort of patients. The association appears most marked when the two virological parameters are considered together rather than individually. The association is not always a tight one. and this may relate to a number of unmeasured factors. including viral phenotype. plasma viremia. and the immune response to HIV infection. Additional work incorporating these parameters into analysis is currently underway in the authors’ centre.
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20

LoVerde, Philip T., and David J. Wyler. "Modern Parasite Biology: Cellular, Immunological and Molecular Aspects." Journal of Parasitology 78, no. 3 (June 1992): 523. http://dx.doi.org/10.2307/3283657.

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21

Vass, Emily, and Anthony J. Nappi. "Developmental and Immunological Aspects of Drosophila-Parasitoid Relationships." Journal of Parasitology 86, no. 6 (December 2000): 1259. http://dx.doi.org/10.2307/3285011.

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22

Kishnani, Priya S. "Immunological aspects of treatment of Pompe disease." Clinical Therapeutics 32 (January 2010): S49—S50. http://dx.doi.org/10.1016/s0149-2918(10)80001-3.

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23

Hoozemans, Jeroen J. M., Annemieke J. M. Rozemuller, Robert Veerhuis, and Piet Eikelenboom. "Immunological Aspects of Alzheimer??s Disease." BioDrugs 15, no. 5 (2001): 325–37. http://dx.doi.org/10.2165/00063030-200115050-00004.

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24

Dressler, Dirk, and Hans Bigalke. "Immunological aspects of botulinum toxin therapy." Expert Review of Neurotherapeutics 17, no. 5 (November 28, 2016): 487–94. http://dx.doi.org/10.1080/14737175.2017.1262258.

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25

Cohen-Inbar, Or, and Menashe Zaaroor. "Immunological Aspects of Malignant Gliomas." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 43, no. 4 (April 13, 2016): 494–502. http://dx.doi.org/10.1017/cjn.2016.34.

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AbstractGlioblastoma Multiforme (GBM) is the most common malignant primary brain neoplasm having a mean survival time of <24 months. This figure remains constant, despite significant progress in medical research and treatment. The lack of an efficient anti-tumor immune response and the micro-invasive nature of the glioma malignant cells have been explained by a multitude of immune-suppressive mechanisms, proven in different models. These immune-resistant capabilities of the tumor result in a complex interplay this tumor shares with the immune system. We present a short review on the immunology of GBM, discussing the different unique pathological and molecular features of GBM, current treatment modalities, the principles of cancer immunotherapy and the link between GBM and melanoma. Current knowledge on immunological features of GBM, as well as immunotherapy past and current clinical trials, is discussed in an attempt to broadly present the complex and formidable challenges posed by GBM.
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26

Burt, Helen. "Microspheres and drug therapy—pharmacological, immunological and medical aspects." Journal of Pharmacological Methods 15, no. 2 (April 1986): 187–88. http://dx.doi.org/10.1016/0160-5402(86)90067-7.

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27

Borek, F. "Microspheres and drug therapy: Pharmaceutical, immunological and medical aspects." Journal of Immunological Methods 85, no. 1 (December 1985): 227. http://dx.doi.org/10.1016/0022-1759(85)90291-1.

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28

Łacheta, Dominika, Piotr Miśkiewicz, Alicja Głuszko, Grażyna Nowicka, Maria Struga, Ireneusz Kantor, Krzysztof B. Poślednik, Shafaq Mirza, and Mirosław J. Szczepański. "Immunological Aspects of Graves’ Ophthalmopathy." BioMed Research International 2019 (November 12, 2019): 1–12. http://dx.doi.org/10.1155/2019/7453260.

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The body’s autoimmune process is involved in the development of Graves’ disease (GD), which is manifested by an overactive thyroid gland. In some patients, autoreactive inflammatory reactions contribute to the development of symptoms such as thyroid ophthalmopathy, and the subsequent signs and symptoms are derived from the expansion of orbital adipose tissue and edema of extraocular muscles within the orbit. The autoimmune process, production of antibodies against self-antigens such as TSH receptor (TSHR) and IGF-1 receptor (IGF-1R), inflammatory infiltration, and accumulation of glycosaminoglycans (GAG) lead to edematous-infiltrative changes in periocular tissues. As a consequence, edema exophthalmos develops. Orbital fibroblasts seem to play a crucial role in orbital inflammation, tissue expansion, remodeling, and fibrosis because of their proliferative activity as well as their capacity to differentiate into adipocytes and myofibroblasts and production of GAG. In this paper, based on the available medical literature, the immunological mechanism of GO pathogenesis has been summarized. Particular attention was paid to the role of orbital fibroblasts and putative autoantigens. A deeper understanding of the pathomechanism of the disease and the involvement of immunological processes may give rise to the introduction of new, effective, and safe methods of treatment or monitoring of the disease activity.
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29

Gazzinelli-Guimarães, Pedro Henrique, Ana Clara Gazzinelli-Guimarães, Flaviane Nunes Silva, Vitor Luís Tenório Mati, Lucas de Carvalho Dhom-Lemos, Fernando Sérgio Barbosa, Lívia Silva Araújo Passos, et al. "Parasitological and immunological aspects of early Ascaris spp. infection in mice." International Journal for Parasitology 43, no. 9 (August 2013): 697–706. http://dx.doi.org/10.1016/j.ijpara.2013.02.009.

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30

Evengård, Birgitta. "Schistosomiasis: Immunological, Serological and Clinical Aspects." Scandinavian Journal of Infectious Diseases 21, sup63 (March 1989): 1–72. http://dx.doi.org/10.3109/inf.1989.21.suppl-63.01.

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31

M�ller, Norbert. "Immunological and infectious aspects of schizophrenia." European Archives of Psychiatry and Clinical Neuroscience 254, no. 1 (February 1, 2004): 1–3. http://dx.doi.org/10.1007/s00406-004-0477-2.

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32

Morukov, B. V., M. P. Rykova, E. N. Antropova, T. A. Berendeeva, I. B. Morukov, and S. A. Ponomarev. "Immunological aspects of a space flight to Mars." Human Physiology 39, no. 2 (March 2013): 126–35. http://dx.doi.org/10.1134/s0362119713020102.

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33

Khan, Ashraful I., Fahima Chowdhury, Daniel T. Leung, Regina C. Larocque, Jason B. Harris, Edward T. Ryan, Stephen B. Calderwood, and Firdausi Qadri. "Cholera in pregnancy: Clinical and immunological aspects." International Journal of Infectious Diseases 39 (October 2015): 20–24. http://dx.doi.org/10.1016/j.ijid.2015.08.006.

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34

Dragojevic-Dikic, Svetlana, Mladenko Vasiljevic, Branka Nikolic, Vladimir Pazin, Lidija Tasic, Aleksandar Jurisic, Srdjan Dikic, and Zivko Perisic. "Premature ovarian failure: Immunological aspects and therapeutic strategies." Vojnosanitetski pregled 70, no. 11 (2013): 1051–55. http://dx.doi.org/10.2298/vsp1311051d.

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35

Luna, KPO, MB da Silva, and VRA Pereira. "Clinical and immunological aspects of envenomations by Bothrops snakes." Journal of Venomous Animals and Toxins including Tropical Diseases 17, no. 2 (2011): 130–41. http://dx.doi.org/10.1590/s1678-91992011000200003.

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36

Sazhin, A. V., V. A. Petukhov, T. V. Nechay, G. B. Ivakhov, E. A. Stradymov, A. I. Akperov, and A. A. Rubtsov. "MICROBIOLOGICAL AND IMMUNOLOGICAL ASPECTS OFPATHOGENESISOFACUTE APPENDICITIS." Novosti Khirurgii 29, no. 2 (April 21, 2021): 221–33. http://dx.doi.org/10.18484/2305-0047.2021.2.221.

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Obstruction of the lumen of the appendix is still considered to be the main cause of acute appendicitis (including feces), followed by the increased intraluminal pressure, the development of ischemia and mucosal hypoxia of the appendix, ulceration, violation of the mucous barrier and the development of necrosis. A sufficient number of scientific facts have been accumulated completely refuting this postulate. Current fundamental achievements in molecular biology, biochemistry, etc. did not become the basis for a clinical revision of the ancient well-established theories and concepts of the etiopathogenesis of many diseases in almost all medical specialties. Surgery isn’t an exception in this context. The review considers the etiopathogenesis of acute inflammation of the appendix from the current point of view of the hypothesis of epithelial-endothelial dysfunction and epithelial-endothelial distress syndrome, since it most fully characterizes the integration of the etiopathogenesis of almost all common diseases of organs with mucous membranes and the recent fundamental research their structures and functions. It is based on general and local factors of violation of the lymphoid apparatus and the integumentary epithelium barrier functions. Thus, this work presents a new concept of the etiopathogenesis of acute appendicitis, which in turn will allow the surgery of acute appendicitis to reach new levels of understanding.
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37

Itoh, Mitsuyasu. "Immunological aspects of diabetes mellitus: Prospects for pharmacological modification." Pharmacology & Therapeutics 44, no. 3 (January 1989): 351–406. http://dx.doi.org/10.1016/0163-7258(89)90008-9.

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38

Islam, Shamim, Stephen P. Luby, Mohammed Ashraful Alam Bhuiyan, Rashidul Haque, M. W. Rahman, Masayo Ozaki, M. M. Zahid, et al. "Clinical and Immunological Aspects of Post–Kala-Azar Dermal Leishmaniasis in Bangladesh." American Journal of Tropical Medicine and Hygiene 89, no. 2 (August 7, 2013): 345–53. http://dx.doi.org/10.4269/ajtmh.12-0711.

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39

PEDERSEN, ANNE. "Recurrent aphthous ulceration: Virological and immunological aspects." APMIS 101, S37 (October 1993): 5–37. http://dx.doi.org/10.1111/j.1600-0463.1993.tb05468.x.

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40

Giometto, Bruno, Marika Vianello, Mauro Zoccarato, and Roberta Vitaliani. "Clinical, Immunological and Therapeutic Aspects of Autoimmune Encephalitis." Recent Patents on CNS Drug Discovery 3, no. 1 (January 1, 2008): 16–22. http://dx.doi.org/10.2174/157488908783421465.

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41

Somberg, John. "Immunological Aspects of Neoplasm - The Role of the Thymus." American Journal of Therapeutics 12, no. 5 (September 2005): 473. http://dx.doi.org/10.1097/01.mjt.0000185636.82263.01.

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42

Gutiérrez-González, Luis Horacio, Esmeralda Juárez, Claudia Carranza, Laura E. Carreto-Binaghi, Alejandro Alejandre, Carlos Cabello-Gutiérrrez, and Yolanda Gonzalez. "Immunological Aspects of Diagnosis and Management of Childhood Tuberculosis." Infection and Drug Resistance Volume 14 (March 2021): 929–46. http://dx.doi.org/10.2147/idr.s295798.

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43

Toledo, VPCP, W. Mayrink, KJ Gollob, MAP Oliveira, CA da Costa, O. Genaro, JA Pinto, and LCC Afonso. "Immunochemotherapy in American cutaneous leishmaniasis: immunological aspects before and after treatment." Memórias do Instituto Oswaldo Cruz 96, no. 1 (January 2001): 89–98. http://dx.doi.org/10.1590/s0074-02762001000100010.

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44

Alarcón de Noya, B., J. P. Pointier, C. Colmenares, A. Théron, C. Balzan, I. M. Cesari, S. González, and O. Noya. "Natural Schistosoma mansoni infection in wild rats from Guadeloupe: parasitological and immunological aspects." Acta Tropica 68, no. 1 (October 1997): 11–21. http://dx.doi.org/10.1016/s0001-706x(97)00068-5.

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45

Domingos, Janine, Anaxore Casimiro, Daniela Portugal-Calisto, Luís Varandas, Fátima Nogueira, and Marcelo Sousa Silva. "Clinical, laboratorial and immunological aspects of severe malaria in children from Guinea-Bissau." Acta Tropica 185 (September 2018): 46–51. http://dx.doi.org/10.1016/j.actatropica.2018.04.020.

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46

Jensen, James B., and John A. Vande Waa. "Epidemiological and immunological aspects of human crisis form factor in falciparum malaria: Cell-mediated responses?" Veterinary Parasitology 29, no. 2-3 (September 1988): 171–77. http://dx.doi.org/10.1016/0304-4017(88)90124-0.

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47

Luz, Jean Carlos dos Santos da, Fernanda Antunes, Maria Alejandra Clavijo-Salomon, Emanuela Signori, Nayara Gusmão Tessarollo, and Bryan E. Strauss. "Clinical Applications and Immunological Aspects of Electroporation-Based Therapies." Vaccines 9, no. 7 (July 2, 2021): 727. http://dx.doi.org/10.3390/vaccines9070727.

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Reversible electropermeabilization (RE) is an ultrastructural phenomenon that transiently increases the permeability of the cell membrane upon application of electrical pulses. The technique was described in 1972 by Neumann and Rosenheck and is currently used in a variety of applications, from medicine to food processing. In oncology, RE is applied for the intracellular transport of chemotherapeutic drugs as well as the delivery of genetic material in gene therapies and vaccinations. This review summarizes the physical changes of the membrane, the particularities of bleomycin, and the immunological aspects involved in electrochemotherapy and gene electrotransfer, two important EP-based cancer therapies in human and veterinary oncology.
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48

Hodgson, H. J. F. "Immunological aspects of inflammatory bowel diseases of the human gut." Agents and Actions 36, no. 3-4 (July 1992): C27—C31. http://dx.doi.org/10.1007/bf01996092.

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49

Hodgson, H. J. F. "Immunological aspects of inflammatory bowel diseases of the human gut." Agents and Actions 36, S1 (March 1992): C27—C31. http://dx.doi.org/10.1007/bf01991020.

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50

Zerpa, Olga, Marian Ulrich, Margarita Benitez, Concepción Ávila, Vestalia Rodríguez, Marta Centeno, Doris Belizario, Steven G. Reed, and Jacinto Convit. "Epidemiological and immunological aspects of human visceral leishmaniasis on Margarita Island, Venezuela." Memórias do Instituto Oswaldo Cruz 97, no. 8 (December 2002): 1079–83. http://dx.doi.org/10.1590/s0074-02762002000800002.

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