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Dissertations / Theses on the topic 'Immunological aspects'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Ramshaw, Anna Louise. "Immunological aspects of human atherosclerosis." Thesis, University of Oxford, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.305549.

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2

Havranek, Erik Georg Ulrich. "Immunological aspects of renal cancer." Thesis, St George's, University of London, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.430426.

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3

Porter, S. R. "Immunological aspects of rapidly progressive periodontitis." Thesis, University of Bristol, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.377350.

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4

Kong, Wai-kwan Wendy, and 江慧君. "The effects of immune activation in the pathogenesis of neurodevelopmental disorders : in vivo and in vitro animal studies." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/197539.

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Schizophrenia and autism are psychiatric disorders with a presumed neurodevelopmental origin, characterised by clinical features and aetiologies that overlap at multiple levels. In addition to genetic susceptibility, epidemiological studies revealed an association between environmental factors and these disorders. Immune activation in response to infection at early gestation has been identified as one of the key risk factors. Little is known about the underlying mechanism during maternal immune activation (MIA), but extrinsic apoptotic dysregulation has been postulated to play a role in MIA in

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5

Neumann, Andersen Grethe. "Systemic sclerosis : vascular, pulmonary and immunological aspects." Doctoral thesis, Umeå universitet, Reumatologi, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1806.

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In systemic sclerosis (SSc), interstitial lung disease (ILD) and engagement of the vascular system lead to increased morbidity and mortality. The aim of this thesis was to elucidate, in a consecutively included cohort of SSc (limited and diffuse) patients (n = 33), the T cell cytokine profile driving the disease in ILD and to explore the role of matrix metalloproteinase 9 (MMP-9) and its inhibitor: tissue inhibitor of metalloproteinase 1 (TIMP-1) in the extracellular matrix (ECM) degrading process leading to fibrous scarring and honey combing. Moreover, to characterize the role of nitric oxide

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6

Sjöwall, Johanna. "Clinical and Immunological Aspects of Lyme borreliosis." Doctoral thesis, Linköpings universitet, Infektionsmedicin, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-68745.

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Lyme borreliosis (LB) is a tick-borne infection caused by spirochetes of the Borrelia (B.) burgdorferi sensu lato complex. The infection is associated with several clinical features, of which erythema migrans (EM) and neuroborreliosis (NB) are the most common in Europe. The prognosis after antibiotic therapy is generally good. However, some patients may have residual symptoms post-treatment. The cause of the delayed convalescence is unclear. There are several factors that may affect the clinical outcome of LB, for example, the early interaction between the host’s immune response and B. burgdor

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7

Wood, Matthew John Andrew. "Immunological aspects of neural transplantation in rodents." Thesis, University of Oxford, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.333298.

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8

Calvet, Christophe. "Immunological aspects of anticancer electroporation-based treatments." Thesis, Paris 11, 2014. http://www.theses.fr/2014PA114816.

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L'électrochimiothérapie est un traitement anticancéreux utilisé en routine en Europe dans près de 130 centres de traitement du cancer. Le taux de réponse objective atteint 85 % pour le traitment de tumeurs cutanées et sous-cutanées et des études sont en cours afin d'appliquer ce traitement à des tumeurs profondes. Au cours de ce doctorat, les méchanismes sous-jacents à cette excellente efficacité antitumorale ont été étudiés. Dans un premier temps, l'objectif a été d'évaluer la capacité de l'électrochimiothérapie à induire la mort des cellules souches cancéreuses, considérées comme les racines

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9

Makarenko, O., O. Molozhava, Тетяна Василівна Івахнюк, et al. "Microbiological and immunological aspects of Alzheimer's disease." Thesis, OMICS International Pvt Ltd, 2017. https://essuir.sumdu.edu.ua/handle/123456789/81108.

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В роботі описані результати мікробіологічних та імунологічних показників пацієнтів з хворобою Альцгеймера.<br>В работе описаны результаты микробиологических и иммунологических показателей пациентов с болезнью Альцгеймера.<br>The paper describes the results of microbiological and immunological parameters of patients with Alzheimer's disease.

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10

Franks, Susan F. (Susan Faye). "Negative Psychological States: Predictors for Immunological Health." Thesis, University of North Texas, 1992. https://digital.library.unt.edu/ark:/67531/metadc332521/.

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Relationships of negative psychological conditions with general status of cell-mediated and humoral immune systems were investigated. A unique approach was utilized in that indexes representing multiple aspects of each branch of the immune system were employed to better indicate general immunological status. Differences in emotion-immune interactions between males and females were demonstrated. Results indicated a positive relationship between Trait Anger and Cell-Mediated Immunological Index. Particular criticisms of previous psychoneuroimmunological research were met by addressing sex differ

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11

吳越 and Yuet Wu. "The study of immune response to co-infection of influenza virus and Streptococcus pneumoniae." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/193417.

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Influenza is a leading cause of respiratory disease worldwide. During pandemic and seasonal influenza, secondary Streptococcus pneumoniae infection is a severe complication that contributes to morbidity and mortality. With the clinical significance of this co-infection, it is imperative to understand the disease mechanisms and how our immune system would be modulated in dealing with the dual infection. First, in vivo co-infection model was established. Mice were sequentially infected with influenza virus and then Streptococcus pneumoniae. Co-infected mice lost their body weight significantl

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12

Arvola, Marie. "Immunological aspects of maternal-foetal interactions in mice." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2001. http://publications.uu.se/theses/91-554-4947-6/.

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13

Boczkowska, Beata. "Aspects of porcine immunological response to Nipah virus." PLoS One, 2012. http://hdl.handle.net/1993/30139.

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Nipah virus (NiV) is a highly pathogenic and zoonotic paramyxovirus in the subfamily Paramyxovirinae, genus Henipavirus. The virus causes outbreaks of severe febrile encephalitis with a high mortality rate in humans, and of encephalitic and respiratory disease but with a low mortality rate in pigs. The innate immune response has a critical role in limiting viral infection by activating antiviral state and adaptive immune response. As pigs are able to overcome the infection with NiV, the working hypothesis was that IFN induced signaling pathways are not completely inhibited by NiV in infecte

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14

Hedin, Skogman Barbro. "Neuroborreliosis in childhood : Clinical, immunological and diagnostic aspects." Doctoral thesis, Linköpings universitet, Pediatrik, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-11520.

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Lyme Borreliosisis is a multi-organ infectious disease caused by the spirochete Borrelia burgdorferi. The spirochete is transmitted to humans by tick bites. Neuroborreliosis (NB) is a disseminated form of the disease, in which the spirochetes invade the nervous system. In children, subacute meningitis and facial nerve palsy are typical clinical manifestations of NB. The aim of this thesis was to study clinical, immunological and laboratory characteristics in children being evaluated for NB in a Lyme endemic area of Sweden, in order to identify factors of importance for prognosis and clinical r

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15

Kennedy, Rebekah Storm. "Microbiological and immunological aspects of equine periodontal disease." Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/8064/.

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Periodontal disease is a common and painful condition in the horse. Although awareness of the condition is growing amongst the veterinary profession and horse owners, the presence of the disease is often overlooked and treatment can be difficult. Despite this, there have been few recent studies of the aetiopathogenesis of the condition. Certain species of bacteria may act as periodontal pathogens, stimulating a destructive inflammatory response in periodontal tissues and this has been well recognised as being important to the aetiopathogenesis of the disease in man. However few equine studies

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16

何柏松 and Pak-chung Ho. "Immunological studies in gestational trophoblastic disease." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1989. http://hub.hku.hk/bib/B31981343.

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17

Middlemiss, Melanie Jane, and n/a. "Aspects of a computational model inspired by immunological principles." University of Otago. Department of Information Science, 2007. http://adt.otago.ac.nz./public/adt-NZDU20071220.150157.

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Nature and biological systems have provided the basis for many computational models and systems, such as neural computing and evolutionary computation. This thesis examines the vertebrate immune system which formed the original basis for Artificial Immune Systems (AIS). The vertebrate immune system is highly complex and, for the most part, is successful at providing us with protection from harmful stimuli. Such a system is attractive as a model to inspire a computational system as it exhibits many desirable behaviours: adaptability, diversity, robustness, efficiency and multiple layers of dete

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18

Norbeck, Oscar. "Clinical and immunological aspects of human parvovirus B19 infection /." Stockholm : Dept. of laboratory medicine, Karolinska institutet, 2005. http://diss.kib.ki.se/2005/91-7140-203-9/.

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19

Wu, Yuet, and 吳越. "Immune response of human monocyte-derived dendritic cells to co-infection of influenza virus and Streptococcus pneumoniae." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45543732.

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20

Li, Jian, and 李健. "Interleukin 17A and interleukin 23 in chronic hepatitis B and hepatocellular carcinoma." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B45875790.

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21

Effertz, Bernard Stephen. "The humoral immune response to streptococcal cell wall-induced arthritis in the rat." Diss., The University of Arizona, 1989. http://hdl.handle.net/10150/184877.

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I investigated the humoral immune response to streptococcal cell walls (SCW) in arthritis susceptible Lewis and resistant Fisher rats. All rats were given a single intraperitoneal injection of either SCW or saline (controls). Rats were sacrificed, three rats per time point, over an eleven week period and serum was collected for ELISA. SCW injected Lewis rats produced anti-SCW antibody, whereas control rats did not. Anti-SCW antibody was significantly elevated over controls between days 14-28 (post injection). Both saline and SCW injected Fisher rats produced anti-SCW antibody, but with differe

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22

Linher, Katja. "Association of markers in genes of the growth hormone axis with the viral load in lymphoid tissues of chickens infected with Marek's disease virus." Thesis, McGill University, 2000. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=33420.

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Vaccination against Marek's disease (MD) is greatly enhanced by host genetic resistance. Genes of the growth hormone (GH) axis have been reported to affect the ontogeny and effector functions of cells of the immune system. Two strains of White Leghorn chickens bred for contrasting homozygous markers in the GH and GH receptor (GHR) genes were challenged with MDV. Contrasts for the significant interaction between marker genotype and tissue indicated that the GH/GHR marker genotype caused a shift in the distribution of the viral load in lymphoid tissues in the two strains. The analysis suggests t

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23

Masilamani, Twinkle Jasmine. "Identification of genetic markers associated with Marek's disease resistance in chickens." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=19691.

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Marek's disease (MD) is a highly contagious and economically important disease in the poultry industry. It is caused by an oncogenic avian herpes virus. The ability of the virus to evolve into new strains is a continual threat. Vaccination, proper management and genetic resistance are required to completely eliminate the pathogen. The discovery of several markers associated with MD resistance shows that genetic selection for resistance is feasible. Our objective was to identify markers in QTL regions that are associated with MD viraemia. The markers analysed were in the ODC gene, the GH gene a

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24

Ahvazi, Behrouz C. "Mechanisms of modulation of immune responses during blood-stage malaria." Thesis, McGill University, 1994. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=26454.

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In this thesis, mechanisms of immunoregulation by CD4$ sp+$ T cells during blood-stage P. chabaudi AS infection in C57BL/6 mice were studied. The kinetics of in vitro production of the Th1-derived cytokine, IFN-$ gamma$, versus the Th2-derived cyokines, IL-4, IL-5 and IL-10, by spleen cells as well as of polyclonal and malaria-specific antibodies in the sera were examined during infection using enzyme-linked immunosorbent assays. Upon antigenic stimulation, spleen cells were found to produce high levels of IFN-$ gamma$ several days prior to peak parasitemia, while high levels of IL-10 producti

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25

de, Boniface Jana. "Sentinel Node Biopsy in Breast Cancer : Clinical and Immunological Aspects." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7890.

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26

Pidverbetska, O. V., D. V. Kovtun, and M. І. Ostafiychuk. "Immunological aspects of immune reconstitution inflammatory syndrome in HIV-infection." Thesis, БДМУ, 2021. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/18025.

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27

Hjorth, Maria. "Immunological profile and aspects of immunotherapy in type 1 diabetes." Doctoral thesis, Linköping : Department of Clinical and Experimental Medicine, Linköping University, 2010. http://www2.bibl.liu.se/liupubl/disp/disp2010/med1161s.pdf.

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28

Walton, Shelley Faye. "Sarcoptes scabiei : a molecular approach to immunological and epidemiological aspects." Thesis, The University of Sydney, 1999. https://hdl.handle.net/2123/27676.

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The aim of this project was to account for and characterise the extent of genetic variation within and between sympatfic host-associated populations of dog-derived and human-derived Sarcoptes scabiei.

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29

Hartaningsih, Nining. "Aetiological and immunological aspects of Jembrana disease in Bali cattle." Thesis, Hartaningsih, Nining (1993) Aetiological and immunological aspects of Jembrana disease in Bali cattle. PhD thesis, Murdoch University, 1993. https://researchrepository.murdoch.edu.au/id/eprint/53267/.

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The clinico-pathological changes in experimentally induced Jembrana disease in Bali cattle (Bos javanicus) were determined as a basis for the differential diagnosis of the disease and increased understanding of the pathogenesis of the disease process. The incubation period varied from 4 to 12 days. The major clinical signs in the experimentally infected cattle were an elevated rectal body temperature persisting for 5 to 12 days, lethargy, anorexia, and enlargement of the superficial lymph nodes. The case fatality rate was 17%. The major haematological changes included a leukopenia characterize

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30

Roy, Mélanie. "Identification and characterization of differentially expressed genes in response to Escherichia coli and Staphylococcus aureus in bovine mammary epithelial cells and mammary gland." Thesis, McGill University, 2006. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=98785.

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Bovine mammary glands respond to infection by foreign pathogens such as Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) through changes in gene expression. Monitoring the gene expression profiles will contribute to better understanding of the pathology of mastitis, and provide important selective markers for future animal breeding programs. Using cultured bovine mammary duct epithelial cells and somatic cells from infected bovine mammary glands, this study first examined the existence of Toll Like Receptors in these two systems. In cultured duct epithelial cells stimulated wit

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31

Boström, Lennart. "Tobacco smoking and periodontal disease : some clinical, microbiological and immunological aspects /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4456-3/.

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32

Sparrelid, Elda. "Infections in allogeneic stem cell transplanted patients : clinical and immunological aspects /." Stockholm, 2001. http://diss.kib.ki.se/2001/91-628-4840-2/.

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33

Shiau, Ai-Li. "Immunological aspects of hepatitis B virus core antigen and its derivatives." Thesis, University of Edinburgh, 1993. http://hdl.handle.net/1842/14415.

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The use of core antigen (HBcAg) of hepatitis B virus (HBV) to present peptide epitopes to the immune system has been shown to enhance immunogenicity of the peptide epitopes. HBcAg fused to the first 8 amino acid residues of β-galactosidase was exploited to serve as a carrier protein to present the epitopes from the S, preS_1 and preS_2 regions of HBV as its truncated C-terminus. The emergence of an HBV escape mutant carrying an amino acid substitution from glycine to arginine at amino acid residue 145 of the S domain suggests that it may be necessary to modify future HBV vaccines. The immunodo

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34

Yip, Ming-shum, and 葉名琛. "Severe acute respiratory syndrome coronavirus infection of human immune cells through antibody-mediated pathway." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B46542139.

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35

Yim, Chi-ho Howard, and 嚴志濠. "Mechanisms of mycobacteria-induced innate responses." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45200981.

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36

Wang, Xiaohui, and 王晓辉. "The role of IL-17A in modulating B cell response during influenza virus infection." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/208035.

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Interleukin-17A (IL-17A)is an important pro-inflammatory cytokine that plays a critical role in host defenses against diverse pathogens. Studies have shown that IL-17Aplays protective role against sub-lethal H1 and H3 subtypes influenza infections, but it is unclear about the role of IL-17A in the highly pathogenic H5N1 and lethal H1N1 influenza virus infection. B cell is an important effector cell type in anti-influenza immunity. Although roles of B cell in influenza infection have been extensively investigated, it is unclear whether and how IL-17AregulatesB cell response during influenza inf

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37

Elliott, Salenna R. "Lymphocyte expression of costimulator molecules in early life /." Title page, contents and summary only, 1999. http://web4.library.adelaide.edu.au/theses/09PH/09phe466.pdf.

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38

Hoedemaekers, Cornelia Wilhelmina Elisabeth. "Age-related resistance to experimental autoimmune myasthenia gravis immunological and neurobiological aspects /." [Maastricht : Maastricht : Universiteit Maastricht] ; University Library, Maastricht University [Host], 1997. http://arno.unimaas.nl/show.cgi?fid=5923.

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39

Sloan, Duncan J. "Some immunological aspects of neural transplantation to the CNS of inbred rats." Thesis, University of Oxford, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.280741.

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40

Maccoll, Gavin Stuart. "Functional and immunological aspects of growth hormone gene transfer into muscle cells." Thesis, University College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326173.

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41

Snyder, Benjamin J. "Immunological Aspects of Muscle Injury and Regeneration in Young and Old Rats." Ohio University / OhioLINK, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1016641263.

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42

del, Fierro Gloria M. "Clinical, immunological and pathological aspects of experimental feline immunodeficiency virus (FIV) infection." Thesis, del Fierro, Gloria M. (1995) Clinical, immunological and pathological aspects of experimental feline immunodeficiency virus (FIV) infection. PhD thesis, Murdoch University, 1995. https://researchrepository.murdoch.edu.au/id/eprint/53477/.

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Feline immunodeficiency virus is a recently discovered feline lentivirus which clinically resembles human HIV-1 virus inducing immune dysfunction and secondary infections in cats. FIV presence has been confirmed throughout the world in domestic, feral and zoo cat populations. Older, free-roaming, diseased male cats are at the greatest risk of acquiring the infection. There are no specific clinical signs restricted to FIV infection. However, weight loss, recurrent fever of undetermined origin, unthriftiness, inappetence, pyrexia, lymphadenopathy, anaemia, leucopenia and myeloproliferative d

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43

Li, Suiyang. "Identification of DNA markers which are associated with egg production traits and Marek's disease resistance in chickens." Thesis, McGill University, 1998. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=35001.

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Production traits and disease resistance are believed to be under the control of many genes, i.e. quantitative trait loci (QTL). The objective of the present study was to establish a methodology for identifying DNA markers which are associated with QTL in chickens using an alternative approach to the traditional linkage analysis. A systematic screening approach was designed to search a chicken liver cDNA library for clones which revealed polymorphisms associated with traits. In the first stage of the experiment, a total of 92 cDNA clones were subjected to restriction fragment length polymorphi

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44

Chan, Tak-mao Daniel, and 陳德茂. "Pathogenesis of systemic lupus erythematosus: interactions between anti-DNA antibodies and vascular endothelialcells." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1994. http://hub.hku.hk/bib/B31981574.

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Yuan, Tingting, and 袁婷婷. "Identification of intermediate antibodies of broadly neutralizing HIV-1 human monoclonal antibody b12 and characterization of variable loops of HIV-1 envelop glycoprotein." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/196445.

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Roscioli, Tony Clinical School Prince of Wales Hospital Faculty of Medicine UNSW. "The genetic basis of veno-occlusive disease with immunodeficiency syndrome." Awarded by:University of New South Wales. Clinical School - Prince of Wales Hospital, 2007. http://handle.unsw.edu.au/1959.4/40599.

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This thesis addresses the genetic basis of a rare autosomal recessive primary immunodeficiency disorder with the characteristic additional feature of venoocclusive disease of the liver (VODI). The interest in this condition was stimulated both by the potential to identify the genetic basis of a rare immunodeficiency and the opportunity to gain an insight into the biological basis of hepatic veno-occlusive disease, a poorly understood condition that is encountered most frequently in Australia as a consequence of bone marrow transplantation. The gene responsible for VODI was identified by homoz

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47

黎祝齡 and Chuk-ling Julian Lai. "The effects of examination stress on secretory immunity." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1993. http://hub.hku.hk/bib/B31234239.

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48

Lam, Suk-fun, and 林淑芬. "Serological response in SARS patients." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B45010201.

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49

Teng, Ooiean, and 丁瑋嫣. "Identification of CLEC5A in modulating host immune response after influenza A virus infection." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/208615.

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Human infections with influenza A virus (IAV) exhibit mild to severe clinical outcomes as a result of differential virus-host interactions. C-type lectin receptors (CLRs) are pattern recognition receptors that may sense carbohydrates, proteins, or lipids derived from infected hosts or the invading microbes including bacteria, viruses, fungi, or parasites. CLR-viral interaction may lead to increased viral entry and spread; furthermore, their interactions have been reported to trigger downstream signaling that further modulates host’s innate immune responses through the induction of pro-inflamma

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50

Yun, Peter Lok Wai. "Disruption Of Cell-Mediated Immune Responses By Gingipains From Porphyromonas Gingivalis." Thesis, The University of Sydney, 2001. http://hdl.handle.net/2123/4966.

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