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1

Embleton, M. J. "Immunology of experimental oncogenesis." Current Opinion in Immunology 1, no. 5 (June 1989): 867–71. http://dx.doi.org/10.1016/0952-7915(89)90062-9.

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2

Pasqualini, Christiane, Raul Ruggiero, Oscar Bustuoabad, Irene Nepomnaschy, and Isabel Piazzon. "Experimental Onco-Immunology Revisited." Current Cancer Therapy Reviews 1, no. 3 (November 1, 2005): 289–98. http://dx.doi.org/10.2174/157339405774574225.

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3

Denman, A. "Handbook of Experimental Immunology." Journal of Clinical Pathology 41, no. 1 (January 1, 1988): 118–19. http://dx.doi.org/10.1136/jcp.41.1.118-b.

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4

Chase, Merrill W. "Immunology and Experimental Dermatology." Annual Review of Immunology 3, no. 1 (April 1985): 1–30. http://dx.doi.org/10.1146/annurev.iy.03.040185.000245.

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5

Behan, Wilhelmina M. H. "Handbook of experimental immunology." Journal of Neuroimmunology 15, no. 2 (June 1987): 217–18. http://dx.doi.org/10.1016/0165-5728(87)90095-6.

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6

Emmrich, Frank. "Handbook of experimental immunology." Immunology Today 7, no. 12 (December 1986): 384–85. http://dx.doi.org/10.1016/0167-5699(86)90032-0.

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7

WEIL, RICHARD. "Transplantation Immunology: Clinical and Experimental." Archives of Surgery 120, no. 12 (December 1, 1985): 1399. http://dx.doi.org/10.1001/archsurg.1985.01390360059016.

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8

Horwitz, David L. "Immunology of Clinical and Experimental Diabetes." JAMA: The Journal of the American Medical Association 253, no. 8 (February 22, 1985): 1182. http://dx.doi.org/10.1001/jama.1985.03350320108034.

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9

Roggero, Eduardo, Ana R. Pérez, Oscar A. Bottasso, Hugo O. Besedovsky, and Adriana Del Rey. "Neuroendocrine-immunology of Experimental Chagas' Disease." Annals of the New York Academy of Sciences 1153, no. 1 (February 2009): 264–71. http://dx.doi.org/10.1111/j.1749-6632.2008.03982.x.

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10

Shortman, Ken. "The experimental foundations of modern immunology." Immunology Today 13, no. 1 (January 1992): 39. http://dx.doi.org/10.1016/0167-5699(92)90206-m.

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11

Orozco-Suarez, Sandra, Iris Feria-Romero, and Israel Grijalva. "Immunology and Epilepsy: Clinical and Experimental Evidence." Current Immunology Reviews 6, no. 3 (August 1, 2010): 185–94. http://dx.doi.org/10.2174/157339510791823691.

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12

Salaman, J. R. "Book Review: Transplantation Immunology: Clinical and Experimental." Journal of the Royal Society of Medicine 78, no. 8 (August 1985): 702. http://dx.doi.org/10.1177/014107688507800833.

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13

Taams, L. S., and R. S. Taylor. "Clinical & Experimental Immunology: Highlights of 2020." Clinical & Experimental Immunology 203, no. 1 (December 16, 2020): 1–2. http://dx.doi.org/10.1111/cei.13557.

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14

Stillwell, Craig R. "Thymectomy as an experimental system in immunology." Journal of the History of Biology 27, no. 3 (1994): 379–401. http://dx.doi.org/10.1007/bf01058991.

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15

Kheirouri, Sorayya, and Mohammad Alizadeh. "Experimental immunology Decreased serum and mucosa immunoglobulin A levels in vitamin A- and zinc-deficient mice." Central European Journal of Immunology 2 (2014): 165–69. http://dx.doi.org/10.5114/ceji.2014.43716.

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16

&NA;, &NA;. "Molecular genetics, immunology and experimental pathology of melanoma." Melanoma Research 4, no. 5 (October 1994): 331. http://dx.doi.org/10.1097/00008390-199410000-00012.

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17

Gaze, S., J. M. Bethony, and M. V. Periago. "Immunology of experimental and natural human hookworm infection." Parasite Immunology 36, no. 8 (August 2014): 358–66. http://dx.doi.org/10.1111/pim.12088.

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18

LIN, Youwei, Sachiko MIYAKE, and Takashi YAMAMURA. "Experimental autoimmune encephalomyelitis: crosstalk with immunology and therapy." Japanese Journal of Clinical Immunology 37, no. 3 (2014): 146–53. http://dx.doi.org/10.2177/jsci.37.146.

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19

Lysіаniy, Mykola, Lyudmyla Belska, Nastya Palamaryova, and Antonina Potapova. "FEATURES OF IMMUNE SYSTEM DISORDERS IN EXPERIMENTAL BRAIN TRAUMA IN RATS." Immunology and Allergy: Science and Practice, no. 1 (April 8, 2020): 58–63. http://dx.doi.org/10.37321/immunology.2020.01-08.

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Introduction. Traumatic brain injury (TBI) is one of the common diseases of the person, which is accompanied by high mortality and disability of the victims. In the pathogenesis of TBI there are at least 2 periods that are associated with both primary nerve cell injury by the traumatic factor and secondary inflammatory-destructive changes that develop over a long period after the injury. An important role in the development of the second period of TBI is played by the body’s immune system, which can complicate the course of TBI and act differently depending on the severity of the injury. The goal of the work. The work investigated the state of proliferative and cytotoxic ability of splenocytes in light TBI in rats, which was caused by a drop in weight of 50 g from a height of 120 cm per animal. Materials and results. Studies have shown that within 24 hours after injury, there is an increase in the proliferative activity of splenocytes in the test for proliferation with mitogens, especially with KonA mitogen. While the cytotoxic activity of splenocytes is significantly inhibited at this time and the number of hyperdiploid cells in the spleen is reduced. At a later date after the injury, for 5 days, there is a significant recovery of immunological parameters, indicating that from the first hours after a mild TBI, the immune system changes in different directions, mainly towards the activation of proliferation, which may complicate the course the traumatic period. Conclusions. In experimental mild TBI, rats have differentiated changes in the activity of immune cells, which indicate the activation of the immune system in the early stages after injury.
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20

Castro, Mario, Grant Lythe, Carmen Molina-París, and Ruy M. Ribeiro. "Mathematics in modern immunology." Interface Focus 6, no. 2 (April 6, 2016): 20150093. http://dx.doi.org/10.1098/rsfs.2015.0093.

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Mathematical and statistical methods enable multidisciplinary approaches that catalyse discovery. Together with experimental methods, they identify key hypotheses, define measurable observables and reconcile disparate results. We collect a representative sample of studies in T-cell biology that illustrate the benefits of modelling–experimental collaborations and that have proven valuable or even groundbreaking. We conclude that it is possible to find excellent examples of synergy between mathematical modelling and experiment in immunology, which have brought significant insight that would not be available without these collaborations, but that much remains to be discovered.
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21

Bellavite, Paolo, Riccardo Ortolani, and Anita Conforti. "Immunology and Homeopathy. 3. Experimental Studies on Animal Models." Evidence-Based Complementary and Alternative Medicine 3, no. 2 (2006): 171–86. http://dx.doi.org/10.1093/ecam/nel016.

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A search of the literature and the experiments carried out by the authors of this review show that there are a number of animal models where the effect of homeopathic dilutions or the principles of homeopathic medicine have been tested. The results relate to the immunostimulation by ultralow doses of antigens, the immunological models of the ‘simile’, the regulation of acute or chronic inflammatory processes and the use of homeopathic medicines in farming. The models utilized by different research groups are extremely etherogeneous and differ as the test medicines, the dilutions and the outcomes are concerned. Some experimental lines, particularly those utilizing mice models of immunomodulation and anti-inflammatory effects of homeopathic complex formulations, give support to a real effect of homeopathic high dilutions in animals, but often these data are of preliminary nature and have not been independently replicated. The evidence emerging from animal models is supporting the traditional ‘simile’ rule, according to which ultralow doses of compounds, that in high doses are pathogenic, may have paradoxically a protective or curative effect. Despite a few encouraging observational studies, the effectiveness of the homeopathic prevention or therapy of infections in veterinary medicine is not sufficiently supported by randomized and controlled trials.
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22

Cruse, Julius M. "The Experimental Foundations of Modern Immunology. William R. Clark." Quarterly Review of Biology 66, no. 4 (December 1991): 532–33. http://dx.doi.org/10.1086/417434.

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23

Collins, William E., and Jurg Gysin. "Experimental models in pathology and immunology (Round table 11 - Summary)." Memórias do Instituto Oswaldo Cruz 87, suppl 3 (1992): 399–400. http://dx.doi.org/10.1590/s0074-02761992000700067.

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24

O'Rand, Michael G. "Second International Conference on Experimental and Clinical Reproductive Immunology, Amsterdam." Journal of Reproductive Immunology 52, no. 1-2 (October 2001): 1–3. http://dx.doi.org/10.1016/s0165-0378(01)00108-5.

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25

Fitch, Frank W. "The Experimental Foundations of Modern Immunology by William R. Clark." Perspectives in Biology and Medicine 28, no. 2 (1985): 326–27. http://dx.doi.org/10.1353/pbm.1985.0066.

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26

Ganzer, U., and C. Bachert. "First Symposium on Experimental Rhinology and Immunology of the Nose." European Archives of Oto-rhino-laryngology 252, S1 (January 1995): S1. http://dx.doi.org/10.1007/bf02484427.

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27

Worliczek, Hanna L., Marc Buggelsheim, Armin Saalmüller, and Anja Joachim. "Porcine isosporosis: Infection dynamics, pathophysiology and immunology of experimental infections." Wiener klinische Wochenschrift 119, S3 (November 2007): 33–39. http://dx.doi.org/10.1007/s00508-007-0859-3.

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28

Taams, Leonie S., and Matthew Perryman. "55 years in the life of Clinical & Experimental Immunology." Clinical & Experimental Immunology 205, no. 3 (August 18, 2021): 275–77. http://dx.doi.org/10.1111/cei.13652.

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29

CAO, Shasha. "Experimental Teaching Methods of Immunology Examination in Higher Vocational Institutions." Journal of International Education and Development 5, no. 2 (2021): 9–13. http://dx.doi.org/10.47297/wspiedwsp2516-250002.20210502.

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30

Piekarska, Jolanta, Michał Gorczykowski, Marianna Szczypka, and Bożena Obmińska-Mrukowicz. "Experimental immunology The influence of immunosuppression on apoptosis and necrosis during experimental trichinellosis in mice." Central European Journal of Immunology 3 (2012): 204–8. http://dx.doi.org/10.5114/ceji.2012.30794.

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31

Bozzano, Federica, Francesco Marras, and Andrea De Maria. "IMMUNOLOGY OF TUBERCULOSIS." Mediterranean Journal of Hematology and Infectious Diseases 6, no. 1 (April 7, 2014): e2014027. http://dx.doi.org/10.4084/mjhid.2014.027.

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MTB ranks as the first worldwide pathogen latently infecting one third of the population and the second leading cause of death from a single infectious agent, after the human immunodeficiency virus (HIV). The development of vigorous and apparently appropriate immune response upon infection with M.tuberculosis in humans and experimental animals conflict with failure to eradicate the pathogen itself and with its ability to undergo clinical latency from which it may exit. From a clinical standpoint, our views on MTB infection may take advantage from updating the overall perspective, that has quite changed over the last decade, following remarkable advances in our understanding of the manipulation of the immune system by M.tuberculosis and of the role of innate components of the immune response, including macrophages, neutrophils, dendritic cells and NK cells in the initial spread of MTB and in its exit from latency. Scope of this review is to highlight the the major mechanisms of MTB escape from immune control and to provide a supplementary translational perspective for the interpretation of innate immune mechanisms with particular impact on clinical aspects.
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32

Loria-Cervera, Elsy Nalleli, and Fernando Jose Andrade-Narvaez. "ANIMAL MODELS FOR THE STUDY OF LEISHMANIASIS IMMUNOLOGY." Revista do Instituto de Medicina Tropical de São Paulo 56, no. 1 (January 2014): 1–11. http://dx.doi.org/10.1590/s0036-46652014000100001.

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Leishmaniasis remains a major public health problem worldwide and is classified as Category I by the TDR/WHO, mainly due to the absence of control. Many experimental models like rodents, dogs and monkeys have been developed, each with specific features, in order to characterize the immune response to Leishmania species, but none reproduces the pathology observed in human disease. Conflicting data may arise in part because different parasite strains or species are being examined, different tissue targets (mice footpad, ear, or base of tail) are being infected, and different numbers (“low” 1×102 and “high” 1×106) of metacyclic promastigotes have been inoculated. Recently, new approaches have been proposed to provide more meaningful data regarding the host response and pathogenesis that parallels human disease. The use of sand fly saliva and low numbers of parasites in experimental infections has led to mimic natural transmission and find new molecules and immune mechanisms which should be considered when designing vaccines and control strategies. Moreover, the use of wild rodents as experimental models has been proposed as a good alternative for studying the host-pathogen relationships and for testing candidate vaccines. To date, using natural reservoirs to study Leishmania infection has been challenging because immunologic reagents for use in wild rodents are lacking. This review discusses the principal immunological findings against Leishmania infection in different animal models highlighting the importance of using experimental conditions similar to natural transmission and reservoir species as experimental models to study the immunopathology of the disease.
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33

Лісяний, Микола, Настя Паламарьова, Людмила Бєльська, and Антоніна Потапова. "CHANGES IN THE CONTENT OF IMMUNE CELLS CONTAINING THE FcR III RECEPTOR IN THE SLEEP AND BRAIN AFTER EXPERIMENTAL TBI." Immunology and Allergy: Science and Practice, no. 2 (July 29, 2020): 60–65. http://dx.doi.org/10.37321/immunology.2020.02-06.

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At TBI there are disturbances in activity of immune system, can complicate regenerative and reparative responses in a brain. The aim of the study was to study the content of CD-16 cells in the spleen and brain parenchyma at different times after TBI in rats and in the correction of disorders in their composition by immunomodulatory drug galalite.Methods. Craniocerebral trauma in animals was modeled by dropping a load weighing 100 g from a height of 120 cm on the head of rats that were anesthetized and were in a state of narcotic sleep, which lasted up to 30 minutes. To correct the resulting disorders used immunomodulatory drug galavit at a dose of 2 mg / kg of animal weight in a volume of0.5 ml, which was administered intramuscularly to animals for 2, 3, 4 days after injury. The spleen and the left and right hemispheres of the brain were homogenized in 5.0 ml of medium 199 and suspensions containing 10.0x106 cells per 1 ml of medium 199 microglia were prepared and infiltrated CNS monocytes were prepared by the method of Sedgwick J. in co-authors. Determination of the level of CD-16 cells in suspensions of spleen and microglia was performed on a flow cytometer using monoclonal antibodies against CD-16 receptor company BD Biosciences according to the instructions for antibodies.Results. In mild TBI in rats, the number of CD- 16 cells containing the FcR III receptor decreases in the spleen for 2 to 5 days, and the number of these cells in the fractions of microglial cells increases. Galavit is a drug with immunomodulatory properties, has virtually no effect on low levels of CD-16 cells in the spleen and stimulates their accumulation in the brain for 10 days after TBI.Conclusions. The results indicate the effect of Galavit on the level of CD-16 cells in the spleen and brain, which indicates the immunomodulatory activity of this drug.
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34

Martins, Paulo Ney Aguiar, and Alexander Filatenkov. "Microsurgical techniques for experimental kidney transplantation and general guidelines to establish studies about transplantation immunology." Acta Cirurgica Brasileira 18, no. 4 (August 2003): 355–80. http://dx.doi.org/10.1590/s0102-86502003000400017.

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Experimental models of organ transplantation played a crucial role to establish the principles of transplantation immunology. The renal transplantation in rodents became the most used model to study the mechanisms of allograft rejection. To perform it, it is necessary to master the microsurgery techniques and the research group should cooperate with other specialists in the field. In this article we review the surgical techniques employed in rats, and we draw guidelines to establish studies about transplantation immunology.
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35

Münz, Christian, and Burkhard Becher. "Experimental immunology in Zürich: The legacy of studying disease-related Ag." European Journal of Immunology 38, no. 11 (November 2008): 2924–26. http://dx.doi.org/10.1002/eji.200890045.

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36

Zhou, Jing, Min Huang, Li-Qing Bi, Su-Ming Zhou, Yun-Lin Cheng, Guo-Xian Ding, and Wei-Hao Sun. "Experimental immunology Bacterial lipoprotein tolerance attenuates cardiac dysfunction in septic mice." Central European Journal of Immunology 3 (2012): 209–20. http://dx.doi.org/10.5114/ceji.2012.30796.

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37

He, Yi, Yuwei Luo, Xiaobin Lao, Liping Tan, and Erwei Sun. "Experimental immunology Cytokine signatures of human whole blood for monitoring immunosuppression." Central European Journal of Immunology 3 (2014): 271–78. http://dx.doi.org/10.5114/ceji.2014.45936.

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38

Vasilev, Sasa, Natasa Ilic, Alisa Gruden-Movsesijan, Sasa Vasilijic, Martina Bosic, and Ljiljana Sofronic-Milosavljevic. "Experimental immunology Necrosis and apoptosis in Trichinella spiralis -mediated tumour reduction." Central European Journal of Immunology 1 (2015): 42–53. http://dx.doi.org/10.5114/ceji.2015.50832.

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39

Benedek, Thomas G. "“Case Neisser”: Experimental Design, the Beginnings of Immunology, and Informed Consent." Perspectives in Biology and Medicine 57, no. 2 (2014): 249–67. http://dx.doi.org/10.1353/pbm.2014.0018.

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40

Mikó, Irén, Endre Bráth, István Furka, Judit Kovács, David Kelvin, and Robert Zhong. "Spleen autotransplantation in mice: A novel experimental model for immunology study." Microsurgery 21, no. 4 (2001): 140–42. http://dx.doi.org/10.1002/micr.1026.

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41

Xu, Hui Yu, Zhi Wei Chen, and Jie Guan. "Study on Clinical Immunology and Inspection through Creating Virtual Lab." Advanced Materials Research 268-270 (July 2011): 1473–75. http://dx.doi.org/10.4028/www.scientific.net/amr.268-270.1473.

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Because the present science and technology development, clinical epidemic studies and inspection of experiment teaching improved, the emergence of a new model of experimental teaching, such as network visual media experiment, the experimental process with virtual laboratory way vivid show in the student, arouse the students' interest in learning, deepened the student to experiment of understanding. His paper mainly introduced how to use Windows Moviemaker software product virtual laboratory introduction Clinical immunology and test experimental teaching form obsolete, the enthusiasm of students to do the experiments is not high; the experimental teaching means of a single, involved the experiment content is not much, lack the overall ensign, the affect of test is not well; the experiment lesson is insufficient; laboratory equipment is insufficient, cannot satisfy the needs of the students. Now, in view of the above problems there is a new model of experimental teaching, such as network visual media experiment, the experimental process with virtual laboratory way vivid mage display in the student and arouse the students' interest in learning, deepened the student to experiment of understanding[1,2]. This paper mainly introduced how to use Windows Moviemaker software production virtual laboratory.
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42

Rothkötter, H. J., E. Sowa, and R. Pabst. "The pig as a model of developmental immunology." Human & Experimental Toxicology 21, no. 9-10 (September 2002): 533–36. http://dx.doi.org/10.1191/0960327102ht293oa.

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There are many limitations to analyse the developing immune system in humans, thus there is need for experimental animal models to study the environmental influences during the ontogeny of the immune system. However, risk assessment is difficult in using rodent models alone, especially as the intrauterine period of development is much shorter than that of humans. In addition to studies in dogs, the pig provides a variety of experimental approaches for developmental immuno-toxicology. The gestation period is 115 days and the occurrence of the different lines of T and B lymphocytes in the blood and organs of the porcine embryo and fetus is well documented. Fetal porcine B cells represent a naïve population developing without maternal idiotypic–antiidiotypic influences. The postnatal development is highly correlated to sufficient uptake of colostrum during the first 48 hours. Although many immunotoxicological experiments have been performed, there is a limited number of original publications about these studies. With the different strains of standard pigs and miniature pigs available and the rapid growing amount of immunological reagents, the pig represents an important experimental model for cost-effective studies in developmental immunotoxicology to analyse the risk of environmental hazards.
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43

Bellavite, Paolo, Anita Conforti, Valeria Piasere, and Riccardo Ortolani. "Immunology and Homeopathy. 1. Historical Background." Evidence-Based Complementary and Alternative Medicine 2, no. 4 (2005): 441–52. http://dx.doi.org/10.1093/ecam/neh141.

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Homeopathy was born as an experimental discipline, as can be seen from the enormous amount of homeopathic data collected over more than two centuries. However, the medical tradition of homeopathy has been separated from that of conventional science for a long time. Conventional scientific wisdom dictates that homeopathy should have no effect above placebo but experiments on ultra-high dilutions of solutes together with some clinical data suggest the intriguing possibility that it might do in some circumstances. Today, an osmotic process between disciplines, previously seen as in conflict, is facilitated because over the last few decades homeopathy has initiated the methods of current medical science and a substantial number of experimental studies—at molecular, cellular and clinical levels—are available. One area of dialogue and of common progress is that of inflammation and immunity, probably because these are closely related to the traditional ‘vital force’ of the body's self-healing power. In a series of papers we review the historical origins of homeopathy, the laboratory and animal models related to the field of immunopharmacology, the clinical evidence in favor and against the use of homeopathy in the inflammatory diseases and the hypotheses regarding its action mechanism(s). Finally, we will enlighten the specific characteristics of the homeopathic approach, which places great emphasis on identifying a cure for the whole organism.
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44

Darcy, F., and L. Zenner. "Experimental models of toxoplasmosis." Research in Immunology 144, no. 1 (January 1993): 16–23. http://dx.doi.org/10.1016/s0923-2494(05)80091-4.

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45

Gebhardt, Bryan M., and Weiyun Shi. "Experimental Corneal Allograft Rejection." Immunologic Research 25, no. 1 (2002): 01–26. http://dx.doi.org/10.1385/ir:25:1:01.

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46

Schuyler, Mark, Katherine Gott, and Pat Haley. "Experimental murine hypersensitivity pneumonitis." Cellular Immunology 136, no. 2 (September 1991): 303–17. http://dx.doi.org/10.1016/0008-8749(91)90354-e.

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47

Demoly, P., A. Campbell, B. Lebel, and J. Bousquet. "Experimental models in rhinitis." Clinical & Experimental Allergy 29 (July 1999): 72–76. http://dx.doi.org/10.1046/j.1365-2222.1999.00010.x-i1.

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48

Holgate, S. T. "Experimental models in asthma." Clinical & Experimental Allergy 29 (July 1999): 82–86. http://dx.doi.org/10.1046/j.1365-2222.1999.0290s3082.x.

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49

Garside. "Cytokines in experimental colitis." Clinical & Experimental Immunology 118, no. 3 (December 1999): 337–39. http://dx.doi.org/10.1046/j.1365-2249.1999.01088.x.

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50

Thomas, Wayne Robert. "Translation of experimental immunotherapy." Allergy 76, no. 1 (January 2021): 12–13. http://dx.doi.org/10.1111/all.14544.

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