Relevant bibliographies by topics / Immunology; Tumour cells

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Immunology; Tumour cells'

Author: Grafiati
Published: 4 June 2021
Last updated: 10 February 2022

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Journal articles on the topic "Immunology; Tumour cells"

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Alotaibi, Faizah, Mark Vincent, Weiping Min, and James Koropatnick. "498 Downregulation of CD5 in CD8+ T tumour-infiltrating lymphocytes associates with increased level of activation and exhaustion." Journal for ImmunoTherapy of Cancer 8, Suppl 3 (2020): A533. http://dx.doi.org/10.1136/jitc-2020-sitc2020.0498.

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BackgroundCD5, a member of the scavenger receptor cysteine-rich superfamily, is a marker for T cells and a subset of B cells (B1a). CD5 associates with T-cell and B-cell receptors and impair TCR signaling1 2 and increased CD5 is an indication of B cell activation. Furthermore, CD5 levels on CD8+ T cell splenocytes were significantly increased after TCR/CD3 stimulation using ex vivo treatment with anti-CD3/anti-CD28 MAbs compared to non-stimulated CD8+ T splenocytes.3 Previous studies have shown a correlation between CD5 and anti-tumour immunity where CD5 knockout mice inoculated with B16F10 me
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Ahmad, Sharon. "Tumour cells tout trogocytosis." Nature Reviews Immunology 7, no. 4 (2007): 250–51. http://dx.doi.org/10.1038/nri2068.

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Cerundolo, Vincenzo. "Tumour immunology: T cells work together to fight cancer." Current Biology 9, no. 18 (1999): R695—R697. http://dx.doi.org/10.1016/s0960-9822(99)80442-4.

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Eyileten, Ceren, Kinga Majchrzak, Zofia Pilch, et al. "Immune Cells in Cancer Therapy and Drug Delivery." Mediators of Inflammation 2016 (2016): 1–13. http://dx.doi.org/10.1155/2016/5230219.

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Recent studies indicate the critical role of tumour associated macrophages, tumour associated neutrophils, dendritic cells, T lymphocytes, and natural killer cells in tumourigenesis. These cells can have a significant impact on the tumour microenvironment via their production of cytokines and chemokines. Additionally, products secreted from all these cells have defined specific roles in regulating tumour cell proliferation, angiogenesis, and metastasis. They act in a protumour capacityin vivoas evidenced by the recent studies indicating that macrophages, T cells, and neutrophils may be manipul
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Real, Carla, Francisco Caiado, Catia Igreja, et al. "Delta Like 4 Expressing Bone Marrow-Derived Endothelial Progenitor Cells Regulate Tumour Angiogenesis." Blood 110, no. 11 (2007): 3728. http://dx.doi.org/10.1182/blood.v110.11.3728.3728.

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Abstract Bone marrow-derived endothelial progenitor cells (BM-EPCs) have been implicated in adult neoangiogenesis and consequently used as therapies for human pathologies with endothelial damage. The administration of these cells in human patients temporally improves endothelial function, although the engraftment of these cells in newly formed vessels is inefficient. Conversely, therapeutic stratagies to block EPC contribution during tumor angiogenesis have been proposed. In this work, we analysed the role of the Notch/Delta signalling pathway in EPC function during tumour neoangiogenesis, by
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Schröder, Sabine, Simone Broese, Jana Baake, et al. "Effect of Ionizing Radiation on Human EA.hy926 Endothelial Cells under Inflammatory Conditions and Their Interactions with A549 Tumour Cells." Journal of Immunology Research 2019 (September 2, 2019): 1–14. http://dx.doi.org/10.1155/2019/9645481.

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Purpose. Most tumours are characterized by an inflammatory microenvironment, and correlations between inflammation and cancer progression have been shown. Endothelial cells (ECs), as part of the tumour microenvironment, play a crucial role in inflammatory processes as well as in angiogenesis and could be critical targets of cancer therapy like irradiation. Therefore, in the present study we investigated the effect of ionizing radiation on endothelial cells under inflammatory conditions and their interactions with tumour cells. Methods. Nonactivated and TNF-α treatment-activated human EC EA.hy9
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Bordon, Yvonne. "Macrophages throw tumour cells a lifeline." Nature Reviews Immunology 19, no. 4 (2019): 202–3. http://dx.doi.org/10.1038/s41577-019-0148-1.

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Ashman, Leonie K. "The immunogenicity of tumour cells." Immunology and Cell Biology 65, no. 4 (1987): 271–77. http://dx.doi.org/10.1038/icb.1987.31.

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Carpenter, Ben, Sara Ghorashian, Emma Nicholson, et al. "Targeting Therapeutic T Cells to Tumour Niches." Blood 120, no. 21 (2012): 3009. http://dx.doi.org/10.1182/blood.v120.21.3009.3009.

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Abstract Abstract 3009 Background: Interactions between tumour cells and host cells within the microenvironment are important in promoting the development of cancer. Tumor niches provide crucial anti-apoptotic and anti-proliferative signals that drive tumor chemoresistance. The CXCR4-CXCL12 chemokine axis forms a critical component of this niche. CXCL12 produced by stromal cells has direct pro-survival effects upon tumor cells, promotes metastasis and recruits CXCR4-expressing regulatory T cell populations that block anti-tumour immunity. In this study, we have tested the hypothesis that targe
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Battke, Christina, Romana Ruiss, Ulrich Welsch, et al. "Tumour exosomes inhibit binding of tumour-reactive antibodies to tumour cells and reduce ADCC." Cancer Immunology, Immunotherapy 60, no. 5 (2011): 639–48. http://dx.doi.org/10.1007/s00262-011-0979-5.

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Dissertations / Theses on the topic "Immunology; Tumour cells"

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Dearman, Rebecca Jane. "Antibody-dependent destruction of neoplastic cells by celluar effectors." Thesis, University of Southampton, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.276345.

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McDonnell, Alison. "The role of dendritic cells in the cross-presentation of tumour antigens." University of Western Australia. School of Medicine and Pharmacology, 2009. http://theses.library.uwa.edu.au/adt-WU2010.0017.

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[Truncated abstract] A paradox exists in tumour immunology whereby progressive tumour growth exists in parallel with an anti-tumour T cell response. This defective T cell response is thought to result from the induction of T cell tolerance and/or tumour induced immunosuppression, which act to inhibit the activation, differentiation and function of tumour-specific CD8+ T cells. Dendritic cells (DCs) are professional antigen presenting cells (APCs) that are critical to the generation of effective CTL; however their function and phenotype is often defective or altered in tumour-bearing hosts, whi
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Ajzensztejn, Daniel. "Harnessing the immune system to reject cancers through genetic modifications of tumour cells." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:1aafa1f4-ee10-4081-b621-d81b9979d96a.

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The immune system, which defends the body against a wide array of threats, is gaining a growing role in the fight against cancer. For an immunotherapy to be successful, it needs to overcome intrinsically weak tumour-specific immune responses. There are two broad approaches to achieving this goal: targeting the various arms of the immune system or targeting the cancer and its microenvironment. The experiments discussed in this thesis adopt the second approach. Tumours were transduced with a combination of costimulatory molecules: CD48, CD54, CD70 & CD86, the chemokine CX3CL1 and the cytokines:
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Windebank, Kevin. "Early signal transduction events during activation of the cytolytic process in human natural killer cells." Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337563.

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Pullyblank, Anne Maria. "Evaluation of the role of monoclonal antibodies m17-1A, c17-1A and cSF25 in antibody-dependent cell-mediated cytotoxicity and an exploration of the possible mechanisms of action." Thesis, Imperial College London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.268015.

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Petrovic, Kristina. "Exploring the therapeutic potential of CAR-engineered T-cells targeting endothelial markers on tumour and inflamed vasculature." Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/8468/.

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T-cells engineered to target tumour antigens through surface-expressed chimeric antigen receptors (CARs) are highly effective in treating some leukaemias. The challenge is to extend this success to solid tumours. Tumour endothelial marker 8 (TEM8) is a conserved transmembrane protein overexpressed on the vasculature of many solid tumours but low or undetectable on healthy tissues, making it a potential CAR T -cell target. This thesis explores the safety and therapeutic efficacy of this approach by generating five human TEM8-specific CARs, expressing them in T-lymphocytes, and characterising th
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Nirmal, Ajit Johnson. "Deconvolution of the immune landscape of cancer transcriptomics data, its relationship to patient survival and tumour subtypes." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31519.

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The immune response to a given cancer can profoundly influence a tumour's trajectory and response to treatment, but the ability to analyse this component of the microenvironment is still limited. To this end, a number of immune marker gene signatures have been reported which were designed to enable the profiling of the immune system from transcriptomics data from tissue and blood samples. Our initial analyses of these resources suggested that these existing signatures had a number of serious deficiencies. In this study, a co-expression based approach led to the development of a new set of immu
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Chong, Tsung Wen. "Targeting the hypoxic tumour phenotype with specific T-cell immunotherapy." Thesis, University of Oxford, 2004. http://ora.ox.ac.uk/objects/uuid:d22f1d74-44eb-4560-9249-f6127accd1b1.

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Sugiyarto, Gessa. "Characterising the preferential suppression of potent anti-tumour CTL responses by regulatory T cells." Thesis, University of Southampton, 2014. https://eprints.soton.ac.uk/379016/.

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Li, Ka-Kit. "The role of CD8+ regulatory T cells in anti-tumour immune responses in hepatocellular carcinoma." Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/7940/.

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Tumour specific effector T-cells can be detected in the blood and tumours of patients with hepatocellular carcinoma (HCC) but fail to mount effective immune responses. Attempts to amplify anti-tumour immune responses using immunotherapy show promise, but are hampered by the presence of suppressive regulatory T-cells (Treg) that inhibit anti-tumour immune responses. Many different subsets of Treg have since been identified including regulatory T-cells expressing the surface marker CD8 (CD8⁺Treg). A set of experiments was designed in an attempt to increase our understanding on how CD8⁺Treg may d
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Books on the topic "Immunology; Tumour cells"

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service), SpringerLink (Online, ed. Natural Killer Cells: At the Forefront of Modern Immunology. Springer-Verlag Berlin Heidelberg, 2010.

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A, Berzofsky Jay, and SpringerLink (Online service), eds. Natural Killer T cells: Balancing the Regulation of Tumor Immunity. Springer Science+Business Media, LLC, 2012.

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service), SpringerLink (Online, ed. Innate and Adaptive Immunity in the Tumor Microenvironment. Springer Science + Business Media, LLC, 2008.

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Tumor-infiltrating lymphocytes in human malignancies. R.G. Landes Co., 1993.

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Alexander, Michael A. Immune-based cancer treatment: The T lymphocyte response. CRC Press, 2011.

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(Editor), Giorgio Parmiani, and Michael T. Lotze (Editor), eds. Tumor Immunology: Molecularly Defined Antigens and Clinical Applications (Tumor Immunology and Immunotherapy). CRC, 2002.

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Giorgio, Parmiani, and Lotze Michael T, eds. Tumor immunology: Molecularly defined antigens and clinical applications. Taylor & Francis, 2002.

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Alexander, Michael A. Functional and Translational Immunology of Regulatory T Cells (Tregs), the Anti-Tumor T Cell Response, and Cancer. Nova Science Publishers, Incorporated, 2014.

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1956-, Stauss Hans J., Kawakami Yutaka, and Parmiani Giorgio, eds. Tumor antigens recognized by T cells and antibodies. Taylor & Francis, 2003.

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1956-, Stauss Hans J., Kawakami Yutaka, and Parmiani Giorgio, eds. Tumor antigens recognised by T cells and antibodies. Taylor & Francis, 2003.

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Book chapters on the topic "Immunology; Tumour cells"

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Todryk, Stephen, Selman Ali, Angus Dalgleish, and Robert Rees. "Genetically modified tumour cells for cancer immunization." In Cancer Immunology. Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-017-0963-7_11.

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Vánky, F., E. Klein, J. Willems, K. Böök, T. Ivert, and A. Péterffy. "Recognition of Autologous Tumour Cells by Blood Lymphocytes in Patients with Lung Cancer." In Immunology of Malignant Diseases. Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-3219-7_7.

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Onji, Morikazu. "Dendritic Cells in Tumor Immunology." In Dendritic Cells in Clinics. Springer Japan, 2004. http://dx.doi.org/10.1007/978-4-431-67011-7_6.

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Wei, Wei-Zen, and Gloria H. Heppner. "Breast cancer immunology." In Mammary Tumor Cell Cycle, Differentiation, and Metastasis. Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-1259-8_19.

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Kim, Chang H. "Regulatory T-Cells and Th17 Cells in Tumor Microenvironment." In Cancer Immunology. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-30845-2_6.

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Pisapia, David, and Ehud Lavi. "Tumor-Infiltrating T Cells." In Encyclopedia of Medical Immunology. Springer New York, 2014. http://dx.doi.org/10.1007/978-0-387-84828-0_10.

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Denton, Alice E., Edward W. Roberts, and Douglas T. Fearon. "Stromal Cells in the Tumor Microenvironment." In Stromal Immunology. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-78127-3_6.

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Wolf, J., M. Pawlita, J. Bullerdick, and H. zur Hausen. "Tumor Suppression in Somatic Cell Hybrids Between Burkitt’s Lymphoma Cells and EBV-Immortalized Lymphoblastoid Cells." In Progress in Immunology. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-83755-5_66.

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Gulic, Tamara, Rita Silva-Gomes, Sadaf Davoudian, et al. "Tumor-Associated Myeloid Cells in Cancer Progression." In Cancer Immunology. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-30845-2_3.

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Tavakolpour, Soheil, and Mohammad Darvishi. "The Roles of CD4+ T-Cells in Tumor Immunity." In Cancer Immunology. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-30845-2_5.

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Conference papers on the topic "Immunology; Tumour cells"

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Chan, Isaac S., Hildur Knútsdóttir, Gayathri Ramakrishnan, et al. "Abstract PO039: Cancer cells educate natural killer cells to a metastasis-promoting cell state." In Abstracts: AACR Virtual Special Conference: Tumor Immunology and Immunotherapy; October 19-20, 2020. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/2326-6074.tumimm20-po039.

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Xu, Yuexin, Alicia J. Morales, Andrea M. H. Towlerton, Edus H. Warren, and Scott S. Tykodi. "Abstract A36: Single-cell characterization of tumor-infiltrating T cells from renal cell carcinoma." In Abstracts: AACR Special Conference on Tumor Immunology and Immunotherapy; November 17-20, 2019; Boston, MA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/2326-6074.tumimm19-a36.

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Aggarwal, Sadhna, Suresh C. Sharma, and Satya N. Das. "Abstract PO082: Significance of Treg cells in pathogenesis of oral squamous cell carcinoma." In Abstracts: AACR Virtual Special Conference: Tumor Immunology and Immunotherapy; October 19-20, 2020. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/2326-6074.tumimm20-po082.

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Sheffer, Michal, Emily Lowry, Nicky Beelen, et al. "Abstract PO041: Landscape of molecular events regulating tumor cell responses to natural killer cells." In Abstracts: AACR Virtual Special Conference: Tumor Immunology and Immunotherapy; October 19-20, 2020. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/2326-6074.tumimm20-po041.

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Kristensen, Nikolaj Pagh, Christina Heeke, Siri A. Tvingsholm, et al. "Abstract A14: Neoepitope-specific CD8+ T cells in adoptive T-cell transfer." In Abstracts: AACR Special Conference on Tumor Immunology and Immunotherapy; November 17-20, 2019; Boston, MA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/2326-6074.tumimm19-a14.

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Cassereau, Luke, Tia DiTommaso, Scott Loughhead, Jonathan Gilbert, Howard Bernstein, and Armon Sharei. "Abstract A55: Vector-free genome editing of immune cells for cell therapy." In Abstracts: AACR Special Conference on Tumor Immunology and Immunotherapy; October 1-4, 2017; Boston, MA. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/2326-6074.tumimm17-a55.

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Gordon, Stuart, Bonnie Sloane, Phil Cavanugh, Barbara Cross, Kenneth Honn, and Mohanathasan Chelladurai. "PURIFICATION AND CHARACTERIZATION OF TWO PROCOAGULANTS FROM WALKER 256 CARCINOSARCOMA TUMORS,." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643666.

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Activation of the coagulation system bytumor cells may play an important role in tumor growth and metastases. Becauseprocoagulant activities have been identified in different tumor cells by different investigators, effective comparison of these activities has been difficult. Therefore, we purified and characterized two different procoagulant proteins from the same Walker 256 tumors. The first procoagulant activity/platelet aggregating activity (PCA/PAA) was purified from a 1% CHAPS detergent extract oftumor homogenate followed by (NH4)2SO4 fractionation, anion exchange and hydrophobic chromato
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Mukherjee, Debarati, Robert Baldi, Ching-Yi Chang, Luigi Racioppi, and Donald P. McDonnell. "Abstract A51: Impact of CaMKK2 inhibition in tumor-associated myeloid cells on CD8+ cytotoxic T-cell recruitment into mammary tumors." In Abstracts: AACR Special Conference on Tumor Immunology and Immunotherapy; November 17-20, 2019; Boston, MA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/2326-6074.tumimm19-a51.

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Pauken, Kristen E., Osmaan Shahid, Kaitlyn A. Lagattuta, et al. "Abstract PO016: Single-cell analyses characterize circulating anti-tumor CD8 T cells and identify markers for their isolation." In Abstracts: AACR Virtual Special Conference: Tumor Immunology and Immunotherapy; October 19-20, 2020. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/2326-6074.tumimm20-po016.

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Ma, Liqian, Lawrence Wang, Adam T. Nelson, et al. "Abstract PR006: 27-Hydroxycholesterol acts on myeloid immune cells to induce T cell dysfunction, promoting breast cancer progression." In Abstracts: AACR Virtual Special Conference: Tumor Immunology and Immunotherapy; October 19-20, 2020. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/2326-6074.tumimm20-pr006.

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