Log in

Relevant bibliographies by topics / Immunoregulatory index / Journal articles

To see the other types of publications on this topic, follow the link: Immunoregulatory index.

Journal articles on the topic 'Immunoregulatory index'

Author: Grafiati

Published: 28 May 2022

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Immunoregulatory index.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Dunaievska, Oksana, Ihor Sokulskyi, Mykola Radzykhovskii, et al. "Immunophysiological State of Dogs According to the Immunoregulatory Index of Their Blood and Spleens." Animals 14, no. 5 (2024): 706. http://dx.doi.org/10.3390/ani14050706.

Full text

Abstract:

In this study, the immunological characteristics of a dog’s body were established, allowing for a quick reaction to any changes in the immune status and the development of an immunodeficiency state. The immunoregulatory blood index was determined to indicate the ratio of T-helpers and T-suppressors. The immunoregulatory index of the spleen was determined as the ratio of CD4+ cells to CD8+ cells in the field of view of a microscope (eyepiece 10, objective 40) after obtaining histological preparations according to generally accepted methods. It was found that the number of T-helpers decreased by

APA, Harvard, Vancouver, ISO, and other styles

2

Shakhov, A. G., L. Yu Sashnina, K. V. Lazutina, Yu Yu Vladimirova, and G. V. Nikonenko. "STATE OF CELLULAR IMMUNITY IN PREGNANT SOWS." Transactions of the educational establishment “Vitebsk the Order of “the Badge of Honor” State Academy of Veterinary Medicine 58, no. 4 (2022): 157–61. http://dx.doi.org/10.52368/2078-0109-2022-58-4-157-161.

Full text

Abstract:

Under the conditions of the pig-breeding complex, the state of cellular immunity in sows during the fetal period of gestation was studied. With the onset of gestation (days 38-40), the animals showed a decrease in non-specific cellular protection, as evidenced by a decrease in the number of circulating active phagocytes, their absorption activity on days 38-40 of gestation, the functional reserve of cells on days 38-40 and 78-81 and suppression of T-cell immunity, manifested by a significant increase in the content of T-lymphocytes-suppressors, a decrease in the number of T-helper cells and th

APA, Harvard, Vancouver, ISO, and other styles

3

Kydyrmoldina, Ainur, Bekbolat Zhetpisbayev, Klara Zharykbasova, Kulyash Tazabayev, and Batiyash Silybaev. "The effect of the Eminium regelii extract on cellular immunity." Annual of Sofia University "St. Kliment Ohridski", Faculty of Biology, Book 2 – Botany 101 (2017): 112–19. http://dx.doi.org/10.60066/gsu.biofac.bot.101.112-119.

Full text

Abstract:

The article presents the results of a study on the effects of the wild medicinal plant Eminium regelii Vved. extract to the body of intact and subjected to emotional stress animals on the background of a long-term low dose of gamma-radiation. The reaction of the animal organism to the effects of radiation, emotional stress and the introduction of the Е. regelii extract were evaluated by the total content of leukocytes, absolute and relative content of lymphocytes (including CD3+, CD4+, CD8+), immunoregulatory index (IRI) and leukocyte migration inhibition reaction (LMIR). The experiments were

APA, Harvard, Vancouver, ISO, and other styles

4

Sokolenko, V. L., and S. V. Sokolenko. "Manifestations of allostatic load in residents of radiation contaminated areas aged 18–24 years." Regulatory Mechanisms in Biosystems 10, no. 4 (2019): 422–31. http://dx.doi.org/10.15421/021963.

Full text

Abstract:

We studied the features of allostatic load (AL) in 100 students aged 18–24 years old who, from birth to adulthood, lived in the territories assigned to the IV radiation zone after the Chornobyl accident (density of soil contamination by isotopes 137Cs 3.7–18.5∙104 Bq/m2) and underwent prolonged exposure to small doses of ionizing radiation. The examined students did not have any clinical signs of the immune-neuroendocrine system dysfunction. 50 people had signs of vegetative-vascular dystonia syndrome (VVD), 48 had signs of moderate hyperthyroidism and 21 had signs of moderate hypothyroidism.

APA, Harvard, Vancouver, ISO, and other styles

5

Kabbani, M. S., L. S. Shchegoleva, and E. Yu Shashkova. "Ratio of immune indices in women of the semi-arid region." Russian Journal of Immunology 27, no. 2 (2024): 287–92. http://dx.doi.org/10.46235/1028-7221-16809-roi.

Full text

Abstract:

Environmental and climatic factors have a significant impact on the immune system, shaping its composition and functions. The semiarid region of Aleppo, characterized by hot, dry summers and moderate, wet and cold winters, is also characterized by environmental pollution such as air pollutants and industrial chemicals. The interaction of these environmental and climatic factors can impair immune function by causing inflammatory responses, compromising the integrity of immune cells, and impairing the body’s ability to mount an effective immune response. To date, the physiological characteristic

APA, Harvard, Vancouver, ISO, and other styles

6

Kozhevnikov, V. A., A. L. Kravtsov, O. M. Kudryavtseva, T. N. Kashtanova, and S. A. Bugorkova. "Activation of T-helper in vitro under the Influence of Yersinia pestis Antigens in People Vaccinated against the Plague." Epidemiology and Vaccinal Prevention 21, no. 5 (2022): 58–63. http://dx.doi.org/10.31631/2073-3046-2022-21-5-58-63.

Full text

Abstract:

Relevance. The search for informative markers for assessing the immunological efficacy of a live plague vaccine remains an urgent scientific task. The goal of the studyAims was to make a comparative assessment of the level helper T-cells activation by CD69 and HLA-DR markers, in people, vaccinated against plague, in an in vitro test, using the disintegrated by ultrasonic Y. pestis cells, grown at temperature 28 °C as a specific stimulator.Materials & Methods. A cytofluorimetric analysis of blood samples of 45 individuals vaccinated against the plague was carried out. The dependence of the

APA, Harvard, Vancouver, ISO, and other styles

7

Demkovych, Andrii, Yurii Bondarenko, Vitaliy Shcherba, Vitalii Luchynskyi, Volodymyr Vitkovskyy, and Volodymyr Machogan. "Quercetin effects on adaptive immune response in experimental periodontitis of bacterial-immune genesis." Pharmacia 68, no. 4 (2021): 877–82. http://dx.doi.org/10.3897/pharmacia.68.e70883.

Full text

Abstract:

In the article was studied the effects of flavonol quercetin on indices of adaptive immune response in experimental animals on the 14th day of the experimental bacterial-immune periodontitis development. Indices of immune protection were determined by the relative number of lymphocytes with CD3+, CD4+, CD8+, CD19+, CD16+ and immunoregulatory index (CD4+ / CD8+) in intact animals and on the 14th day of inflammatory process development in periodontal tissues as well as the therapeutic effects of flavonol quercetin. As a result of the study, characterized changes associated with the activity of b

APA, Harvard, Vancouver, ISO, and other styles

8

Demkovych, Andrii, Yurii Bondarenko, Vitaliy Shcherba, Vitalii Luchynskyi, Volodymyr Vitkovskyy, and Volodymyr Machogan. "Quercetin effects on adaptive immune response in experimental periodontitis of bacterial-immune genesis." Pharmacia 68, no. (4) (2021): 877–82. https://doi.org/10.3897/pharmacia.68.e70883.

Full text

Abstract:

In the article was studied the effects of flavonol quercetin on indices of adaptive immune response in experimental animals on the 14<sup>th</sup> day of the experimental bacterial-immune periodontitis development. Indices of immune protection were determined by the relative number of lymphocytes with CD3+, CD4+, CD8+, CD19+, CD16+ and immunoregulatory index (CD4+ / CD8+) in intact animals and on the 14<sup>th</sup> day of inflammatory process development in periodontal tissues as well as the therapeutic effects of flavonol quercetin. As a result of the study, characterized changes associated

APA, Harvard, Vancouver, ISO, and other styles

9

Shakhov, A. G., L. Yu Sashnina, O. A. Manzhurina, Yu Yu Vladimirova, and G. V. Nikonenko. "EFFECT OF VACCINATION AGAINST CIRCOVIRUS INFECTION ON NONSPECIFIC RESISTANCE IN PIGLETS." Transactions of the educational establishment “Vitebsk the Order of “the Badge of Honor” State Academy of Veterinary Medicine 59, no. 4 (2023): 105–10. http://dx.doi.org/10.52368/2078-0109-2023-59-4-105-110.

Full text

Abstract:

The article presents the results of studying the formation of nonspecific resistance in piglets during vaccination against circovirus infection. It has been established that vaccination is accompanied by activation of the innate immune system. At the same time, vaccination has an effect on the homeostasis of animals, manifested by a decrease in the content of segmented neutrophils, albumins, phagocyte reserve index, immunoregulatory index, an increase in the level of circulating immune complexes and their pathogenicity. To reduce the stress effect on the body during vaccination, it is advisabl

APA, Harvard, Vancouver, ISO, and other styles

10

Vityala, Yethindra. "Immunological Features of Measles in Children." Journal of Communicable Diseases 53, no. 03 (2021): 11–15. http://dx.doi.org/10.24321/0019.5138.202134.

Full text

Abstract:

Background: Despite the availability of a safe and effective vaccine, measles remains endemic in many countries and is the main cause of morbidity and mortality among young children. Therefore, the main objective of the study was to investigate the immunological features of measles in children. Materials and Methods: The immune status of children (n = 72) who were diagnosed with measles, was analysed. Various lymphocyte proportions were determined using monoclonal antibodies and immunofluorescence microscopy. The immunoregulatory index was calculated. Results: The relative content of CD4+ and

APA, Harvard, Vancouver, ISO, and other styles

11

Lin, Chenqiang, Hui Zhang, Longjun Chen, Yu Fang, and Jichen Chen. "Immunoregulatory function of Dictyophora echinovolvata spore polysaccharides in immunocompromised mice induced by cyclophosphamide." Open Life Sciences 16, no. 1 (2021): 620–29. http://dx.doi.org/10.1515/biol-2021-0055.

Full text

Abstract:

Abstract The purpose of this study was to investigate whether the Dictyophora echinovolvata spore polysaccharides (DESP) affect the immunity in immunocompromised mice induced by cyclophosphamide (CTX). The healthy female Kunming mice were randomly divided into six groups, including a normal control (NC) group, a positive control group, a model control (MC) group, and three groups treated with low-, intermediate-, and high-dose polysaccharide, respectively. A series of immunoregulatory properties were determined, including humoral and cellular immunity, immune function, and immune factors of mo

APA, Harvard, Vancouver, ISO, and other styles

12

Yue, Rongcai, Guilin Jin, Shanshan Wei, et al. "Immunoregulatory Effect of Koumine on Nonalcoholic Fatty Liver Disease Rats." Journal of Immunology Research 2019 (February 17, 2019): 1–9. http://dx.doi.org/10.1155/2019/8325102.

Full text

Abstract:

Nonalcoholic fatty liver disease (NAFLD) is the most common and important chronic liver disease all over the world. In the present study, we found that koumine, the main and active ingredient isolated from Gelsemium elegans, has the potential therapeutic effect on NAFLD rats by immunomodulatory activity. Koumine could significantly reduce the level of TG, TC, LDL-C, ALT, and AST in the serum of NAFLD rats and increase the level of HDL-C, reduce the liver index, and improve the adipose-like lesions of liver cells in NAFLD rats. Furthermore, treatment with koumine inhibited the severity of NAFLD

APA, Harvard, Vancouver, ISO, and other styles

13

Bodnіa, K. I., and Yu V. Tanchuk. "Indicators of immunity and functional state of the central nervous system with chronic acquired toxoplasmosis." Shidnoevropejskij zurnal vnutrisnoi ta simejnoi medicini 2023, no. 1 (2023): 51–55. http://dx.doi.org/10.15407/internalmed2023.01.051.

Full text

Abstract:

For the first time, patterns of changes in the ratio of immunity indicators were revealed in chronic acquired toxoplasmosis — leukocyte intoxication index (LII), CD3, immunoregulatory index (IRI), total immunoglobulins, adaptive and compensatory reactions (tension coefficient) and functional state of the central nervous system (CNS) — changes in electroencephalographic research (EEG) according to the stem-diencephalic type — with the help of available informative methods, which allowed to assess the severity of the course, plan treatment and predict the outcome of the disease, without resortin

APA, Harvard, Vancouver, ISO, and other styles

14

Otavina, E. A., O. V. Dolgikh, K. G. Starkova, O. A. Kazakova та A. A. Mazunina. "СHANGES OF IMMUNOREGULATORY INDEXES IN CHILDREN EXPOSED TO STRONTIUM". Medical Immunology (Russia) 20, № 6 (2018): 899–904. http://dx.doi.org/10.15789/1563-0625-2018-6-899-904.

Full text

Abstract:

Evaluation of the immune system parameters can be used in order to assess capacity to adapt under conditions of increased external chemical load, including exposure to metals, which can exert either activating and inhibitory effects upon immune regulation parameters. The aim of this work was the analysis of immunoregulatory markers in a children’s population who consumed water with high strontium content (a sample from the Perm region). We carried out immunological evaluation of the children aged 7 to 12 years, living at a territory with a high strontium content in the drinking water. The comp

APA, Harvard, Vancouver, ISO, and other styles

15

Sergei, Kudryashov I., Marina A. Stenina, Luiza M. Karzakova, Irina M. Grigorieva, Olga I. Autonomova, and Maria V. Shestipalova. "FEATURES OF THE T-IMMUNE SYSTEM IN PATIENTS WITH GLOMERULONEPHRITISES WITH NEPHROTIC SYNDROME." Acta medica Eurasica, no. 1 (March 28, 2024): 10–18. http://dx.doi.org/10.47026/2413-4864-2024-1-10-18.

Full text

Abstract:

The study of issues related to glomerulonephritises with nephrotic syndrome is one of the urgent problems of medicine due to their prevalence worldwide, mainly in the young age group. Medical workers distinguish primary (idiopathic) nephrotic syndrome, which occurs in 80–90% of cases, and secondary nephrotic syndrome, mainly associated with systemic autoimmune diseases, diabetes mellitus and neoplasms. Glomerulonephritises, manifested by nephrotic syndrome (membranous nephropathy, focal segmental glomerulosclerosis, nephropathy with minimal changes), are known to be autoimmune diseases. To dat

APA, Harvard, Vancouver, ISO, and other styles

16

Moslim Allawi, Asmaa, Nisreen Waleed Mustafa, and Ali Mohammed Hadi. "A prospective study of metformin effectiveness as a mammalian target of rapamycin inhibitor and immunoregulator in women with polycystic ovarian syndrome." Journal of Neonatal Surgery 14, no. 1S (2025): 608–17. https://doi.org/10.52783/jns.v14.1585.

Full text

Abstract:

Background Polycystic ovarian syndrome (PCOS) is a common disorder affecting ovary function. it’s thought that an autoimmune regulatory mechanism could mediate its onset. Metformin is an effective medication for PCOS treatment and is proposed to act as an immunoregulatory drug. Objective The present work aimed to study the effectiveness of metformin as a mammalian target of rapamycin (mTOR) inhibitor and immunoregulator in PCOS women. Subjects and Methods A total of 80 blood samples were collected, 30 of them from newly diagnosed PCOS women. Once more, blood samples were taken from them follow

APA, Harvard, Vancouver, ISO, and other styles

17

NOVIKOVA, I. A., A. V. GOMOLYAKO, and M. V. ZLOTNIKOVA. "Clinical and immunological aspects of recurrent, bacterial and viral skin affections." Vestnik dermatologii i venerologii 87, no. 2 (2011): 44–48. http://dx.doi.org/10.25208/vdv993.

Full text

Abstract:

The authors analyzed the subpopulation composition of lymphocytes in the peripheral blood of 69 patients suffering from chronic recurrent furunculosis and herpes at the stage of remission. They revealed similar changes in the form of an increased content of T-helpers and immunoregulatory index. In herpes patients such changes are accompanied with the reduced number of natural killers while in furunculosis patients changes are related to the reduced amount of activated T-lymphocytes. These changes do not depend on the relapse duration or frequency but are related to the number of exacerbations

APA, Harvard, Vancouver, ISO, and other styles

18

Kravtsov, A. L., V. A. Kozhevnikov, S. N. Klyueva, et al. "Cellular Immune Status Indicators of Anti-Plague Vaccinated Persons, Living on the Caspian Sandy Natural Plague Focus Territory." Epidemiology and Vaccinal Prevention 18, no. 4 (2019): 67–74. http://dx.doi.org/10.31631/2073-3046-2019-18-4-67-74.

Full text

Abstract:

Aim. To compare by flow cytometry the cellular immune status indicators in persons, living on the territory of the Caspian sandy natural plague focus for epidemic indications. Materials and methods. Whole blood leukocytes of 120 people were examined by flow cytometry with using the two four-color labeled monoclonal antibody reagents (Cyto-Stat CD45-FITC, CD4-PE, CD8-ECD, CD3-PC5 и Cyto-Stat CD45-FITC, CD56-PE, CD19-ECD, CD3-PC5) and by means of CD95-FITC reagent. The results were taken into account before and in a month and 6 months after vaccination. We were determined in the blood the relati

APA, Harvard, Vancouver, ISO, and other styles

19

Mustafayev, I. A., L. I. Allakhverdieva, and A. V. Bogdanova. "Immune status in bronchopulmonary dysplasia." Kazan medical journal 97, no. 3 (2016): 346–50. http://dx.doi.org/10.17750/kmj2016-346.

Full text

Abstract:

Aim. To study cell-mediated and humoral immunity in bronchopulmonary dysplasia in children.Methods. The inpatient and outpatient medical records of 103 children from the 1st day of life up to 3 years of age: 58 boys and 45 girls, were analyzed. T-lymphocytes helper and suppressor activity markers, the immunoregulatory index, B-lymphocytes markers, concentration of the three main immunoglobulins classes, pro- and anti-inflammatory interleukins, circulating immune complexes were determined.Results.. The helper activity in exacerbation phase was at the lower limit of normal (42.1±0.9) and signifi

APA, Harvard, Vancouver, ISO, and other styles

20

Kou, Xiaohong, Qiong Chen, Xiaoying Ju, Huiping Liu, Wenrong Chen, and Zhaohui Xue. "A tolerant lactic acid bacteria, Lactobacillus paracasei, and its immunoregulatory function." Canadian Journal of Microbiology 60, no. 11 (2014): 729–36. http://dx.doi.org/10.1139/cjm-2014-0383.

Full text

Abstract:

The aim of the present investigation was to isolate a probiotic strain from 23 samples of yurts cheese and 21 samples of kumiss (collected from scattered households in Xinjiang and Inner Mongolia), and from eN-Lac Capsules, a health-promoting product. The isolates were subjected to biochemical characterization analysis and were tested for tolerance to low pH, sodium salt, bile salt, pepsin, and trypsin. 16S DNA sequence analysis was conducted to identify the strain. The possible dose-dependent role of strain LP2 in immunomodulation was investigated using the ICR mouse model (from the Institute

APA, Harvard, Vancouver, ISO, and other styles

21

Dreher, R. "Decreased tissue immunoregulatory index in rheumatoid synovitis, determined by in-situ T-cell phenotyping with monoclonal antibodies." Agents and Actions 19, no. 5-6 (1986): 274–76. http://dx.doi.org/10.1007/bf01971227.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Aziz, Rao Salman, Usman Saeed, Muhammad Imran Ashraf, Shazana Rana, Asif Sohail, and Muhammad Arshad. "Immunoregulatory Effects of Adjuvant therapy with Statins in Rheumatoid Arthritis Population." Pakistan Journal of Medical and Health Sciences 15, no. 8 (2021): 1999–2001. http://dx.doi.org/10.53350/pjmhs211581999.

Full text

Abstract:

Background: Rheumatoid arthritis (RA) is considered by symmetrical peripheral arthritis, synovitis & joint destruction. Statins, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme ductase, significantly reduce coronary artery disease by helping to lower plasma low-density lipoprotein cholesterol levels. Experimental studies, more recently, several clinical trials have convincingly shown that statins play a vital role in Rheumatoid arthritis, primarily due to their anti-inflammatory and immunomodulatory properties. Aim: To assess the effectiveness of statin adjunctive therapy versus standa

APA, Harvard, Vancouver, ISO, and other styles

23

Puchkina, G. A., A. N. Sulima, and A. A. Davidova. "Immunocompetent cells in the tissue of adhesives of patients with adhesion process in the small pelvis." Medical Herald of the South of Russia 12, no. 3 (2021): 72–77. http://dx.doi.org/10.21886/2219-8075-2021-12-3-72-77.

Full text

Abstract:

Objective: To study the morphological features and subpopulation composition of immunocompetent cells of adhesion tissue in women with adhesions of the pelvic organs.Materials and Methods: Th e study was carried out using surgical material obtained from 70 women aged 23 to 40 years. Of these, 50 tissue samples of peritoneal adhesions from patients with adhesions of organs in the small pelvis of I – II degree who underwent adhesiolysis and 20 samples of parietal peritoneum from healthy women who underwent endoscopic sterilization for contraception or completion of generative function. Th e auth

APA, Harvard, Vancouver, ISO, and other styles

24

Trapeznikova, Е. G., V. В. Popov, A. S. Radilov, and V. V. Shilov. "DOSE-DEPENDENT CHARACTER OF DISTURBANCE OF HEMATOPOIETIC AND IMMUNE SYSTEMS FUNCTION, PRODUCTION OF SOME HORMONES IN EXPERIMENTAL URANIUM ACETATE DIHYDRATE EXPOSURE." Toxicological Review 1, no. 1 (2021): 14–19. http://dx.doi.org/10.36946/0869-7922-2021-1-14-19.

Full text

Abstract:

The paper presents the results of an experimental study of the dose-dependent nature of functional changes in the body systems under chronic administration of uranyl acetate dihydrate in doses of 0.5 and 5.0 mg/kg per element for 18 weeks. The study was performed on 45 male outbred rats. It has been shown that uranyl acetate dihydrate in a dose of 0.5 mg/kg had no significant effect on hematological parameters. At the same time, activation of bactericidal activity of neutrophils, a decrease in the immunoregulatory index, and an increase in the blood concentration of tumor necrosis factor (TNF-

APA, Harvard, Vancouver, ISO, and other styles

25

Stosman, К. I., К. V. Sivak, Т. A. Rassokha, and Т. N. Savateeva-Lubimova. "DOSE-DEPENDENT CHARACTER OF DISTURBANCE OF HEMATOPOIETIC AND IMMUNE SYSTEMS FUNCTION, PRODUCTION OF SOME HORMONES IN EXPERIMENTAL URANIUM ACETATE DIHYDRATE EXPOSURE." Toxicological Review 1, no. 1 (2021): 20–26. http://dx.doi.org/10.36946/0869-7922-2021-1-20-26.

Full text

Abstract:

The paper presents the results of an experimental study of the dose-dependent nature of functional changes in the body systems under chronic administration of uranyl acetate dihydrate in doses of 0.5 and 5.0 mg/kg per element for 18 weeks. The study was performed on 45 male outbred rats. It has been shown that uranyl acetate dihydrate in a dose of 0.5 mg/kg had no significant effect on hematological parameters. At the same time, activation of bactericidal activity of neutrophils, a decrease in the immunoregulatory index, and an increase in the blood concentration of tumor necrosis factor (TNF-

APA, Harvard, Vancouver, ISO, and other styles

26

Korytov, K. M., V. I. Dubrovina, V. V. Voytkova, et al. "Efficiency of human plague vaccination in tuvinian natural plague focus. Message 2: dynamics of immune status indicators after revaccination." Acta Biomedica Scientifica 6, no. 5 (2021): 44–56. http://dx.doi.org/10.29413/abs.2021-6.5.5.

Full text

Abstract:

Relevance. In Russia, the live plague vaccine (LPV) is used for specific prophylaxis of plague. Immunological monitoring of humans vaccinated by LPV in order to search for informative diagnostic markers, as well as to improve the tactics of epidemiological surveillance of plague enzootic territories is an urgent area of research.The aim is to assess the parameters of cellular and humoral immunity in humans revaccinated by LPV who permanently reside on territory of the Tuvinian natural plague focus.Materials and methods. The study involved 76 volunteers from the Republic of Tuva, revaccinated b

APA, Harvard, Vancouver, ISO, and other styles

27

Kazanin, Artem A., Valeriy I. Zagrekov, Mikhail Y. Lebedev, et al. "Effect of the method of anesthetic aid on cellular immunity in periprosthetic infection of the hip joint: : a prospective open randomized study." Regional Anesthesia and Acute Pain Management 16, no. 3 (2023): 195–204. http://dx.doi.org/10.17816/ra79502.

Full text

Abstract:

BACKGROUND: Periprosthetic infection after primary hip replacement is a serious complication. For the anesthetic support of revision operations, both general and neuroaxial anesthesia methods can be used. The question of choosing an anesthetic aid that, with adequate modulation of the operational stress response, would have a minimal immunosuppressive effect is relevant. AIM: To examine the effect of general and combined spinalepidural anesthesia during revision operations in patients with periprosthetic hip joint infection on the parameters of cellular immunity. MATERIALS AND METH

APA, Harvard, Vancouver, ISO, and other styles

28

Polyanskiy, Dmitry, and Vladimir Kalinin. "Psychopathological symptoms and indicators of cellular immunity in HIV-infected patients with schizophrenia and schizoaffective disorder." Vestnik nevrologii, psihiatrii i nejrohirurgii (Bulletin of Neurology, Psychiatry and Neurosurgery), no. 4 (April 1, 2020): 6–11. http://dx.doi.org/10.33920/med-01-2004-01.

Full text

Abstract:

The correlation between psychopathological disorders and indicators related to the effector molecule in cell-mediated immunity in HIV-infected patients with schizophrenia and schizoaffective disorder has been studied using comparison of means and regression analysis. HIV infection affects individual indicators of the effector molecule in cellular immunity in patients with paranoid schizophrenia and schizoaffective disorder, and its influence differs in schizophrenia and schizoaffective disorder and in various forms of schizophrenia. The structure of psychopathological disorders in HIV-infected

APA, Harvard, Vancouver, ISO, and other styles

29

Starkova, Kseniya G., Oleg V. Dolgikh, and Olga A. Kazakova. "Features of the immune status of middle and high school students in conditions of high blood content of a number of exogenous chemical impurities." Hygiene and sanitation 100, no. 5 (2021): 501–6. http://dx.doi.org/10.47470/0016-9900-2021-100-5-501-506.

Full text

Abstract:

Introduction. The quality of the habitat and increasing intensity of the educational load determine the negative changes of the health of schoolchildren, associated with a violation of immune mechanisms adaptation. Purpose. Study of features of the immune status of schoolchildren in the conditions of excessive hapten contamination by exogenous chemical factors. Materials and methods. Students who live in territories differing in the formation of excessive human-made chemical contamination (total 162 students) of senior and secondary education levels were examined. The analysis of contaminants

APA, Harvard, Vancouver, ISO, and other styles

30

Dementieva, Elena A., Olga P. Gurina, Aleksandr E. Blinov, Olga N. Varlamova, Georgiy A. Blinov, and Arina A. Stepanova. "Peculiarities of cellular and humoral immunity in 3–12 months old infants with atopic dermatitis." Pediatrician (St. Petersburg) 10, no. 6 (2020): 35–44. http://dx.doi.org/10.17816/ped10635-44.

Full text

Abstract:

The increasing frequency and severity of allergopathology in childhood dictate the need to deepen theoretical knowledge about the pathogenesis of immune reactions in allergies. The aim of the work is to analyze the indicators of cellular and humoral immunity in children of the first year of life suffering from atopic dermatitis. Materials and methods. 61 children were examined. Three groups were formed: group 1 children aged 35 months (30 children), group 2 69 months (19 children), group 3 1012 months (22 children). The study of the immune status was carried out by immunological te

APA, Harvard, Vancouver, ISO, and other styles

31

Kologrivova, I. V., T. E. Suslova, I. V. Vinnitskaya, O. A. Koshelskaya, A. A. Boshchenko, and O. A. Trubacheva. "IMMUNOREGULATORY IMBALANCE AND FUNCTIONAL STATE OF THE HEART IN THE PATIENTS WITH DIABETES MELLITUS TYPE 2." Medical Immunology (Russia) 20, no. 6 (2018): 833–46. http://dx.doi.org/10.15789/1563-0625-2018-6-833-846.

Full text

Abstract:

Diabetes mellitus type 2 is one of the most important non-infectious diseases in the modern world, being an important risk factor of cardiovascular disorders. Changes in left ventricular myocardial diastolic function are observed in diabetic patients independently from other comorbidities. Etiology of the heart failure during diabetes mellitus type 2 is multifactorial, exhibiting cellular, molecular and metabolic aspects. However, its pathophysiological mechanisms are not completely understood. The aim of this study was to evaluate numbers of inflammatory T lymphocytes, i.e., T helper type 1 (

APA, Harvard, Vancouver, ISO, and other styles

32

Veretennikov, S. V., V. V. Trusov, A. A. Dmitriev, and V. S. Suskova. "Immunological aspects of long-term insulin-dependent diabetes mellitus." Kazan medical journal 72, no. 1 (1991): 30–32. http://dx.doi.org/10.17816/kazmj96326.

Full text

Abstract:

The results of a comprehensive study of immune homeostasis in 45 patients with long-term insulin-dependent diabetes mellitus are presented. In 50% of the examined patients, the absolute number of leukocytes was reduced, in a third - the number of lymphocytes and the total population of T-lymphocytes, in every second patient - the number of T-helpers and in a quarter - T-suppressors, and quite significantly. In 50% of patients, a sharp decrease in the immunoregulatory index, a significant decrease in the absolute number of B-lymphocytes were found. A significant increase in the content of activ

APA, Harvard, Vancouver, ISO, and other styles

33

Li, Jing, Ji Wang, Chunlei Liu, Li Fang, and Weihong Min. "Protein Hydrolyzates from Changbai Mountain Walnut (Juglans mandshurica Maxim.) Boost Mouse Immune System and Exhibit Immunoregulatory Activities." Evidence-Based Complementary and Alternative Medicine 2018 (May 28, 2018): 1–10. http://dx.doi.org/10.1155/2018/4576561.

Full text

Abstract:

The Changbai Mountain walnut (Juglans mandshurica Maxim.) is a rich source of essential amino acids. Walnut dregs are byproducts of edible oil production and primarily used as fodder and fertilizers. We systematically examined the effect of three types of walnut protein hydrolyzates—albumin, glutelin, and globin—on the immune system of mice and aimed to provide the theoretical basis for developing and utilizing J. mandshurica Maxim. protein resources. In comparison with the normal control mice, those treated with different doses of walnut proteins showed improved immune indices, including orga

APA, Harvard, Vancouver, ISO, and other styles

34

Sokolenko, V. L., S. V. Sokolenko, V. I. Sheiko, and O. V. Kovalenko. "Interconnection of the immune system and the intensity of the oxidative processes under conditions of prolonged exposure to small doses of radiation." Regulatory Mechanisms in Biosystems 9, no. 2 (2018): 167–76. http://dx.doi.org/10.15421/021825.

Full text

Abstract:

This research studied the interrelationship between the immune and oxidative-antioxidant systems in a group of individuals who had lived for a long time in areas contaminated with radionuclides after the Chernobyl catastrophe and as a result experienced prolonged exposure to small doses of ionizing radiation. We have examined a group of 100 students aged 18–24, where 50 of them formed the control group and the remaining 50 belonged to the experimental group as they arrived from the territories of enhanced radioecological control (IV radiation zone, density of soil contamination by isotope 137C

APA, Harvard, Vancouver, ISO, and other styles

35

Demkovych, A. Ye, Yu I. Bondarenko, and M. M. Yakymchuk. "CHANGES IN THE CELLULAR IMMUNE PROTECTION OF ORGANISM IN THE PROCESS OF CHRONIZATION OF EXPERIMENTAL BACTERIAL-IMMUNE PERIODONTITIS." Ukrainian Dental Almanac, no. 1 (March 21, 2018): 5–8. http://dx.doi.org/10.31718/2409-0255.1.2018.01.

Full text

Abstract:

One of the important factors that leads to damage of structures of the periodontal complex and leads to the formation of inflammatory process of varying degrees is the disruption of immunological processes. The aim of the study was to clarify the pathogenetic role of cellular adaptive immunity in the process of formation of chronic inflammatory reaction in the late period of the experimental bacterial-immune periodontitis. The study was conducted on white, non-breeding, clinically healthy male rats. Experimental bacterial-immune periodontitis in experimental animals was caused by inserti

APA, Harvard, Vancouver, ISO, and other styles

36

Illidge, Tim. "Abstract SY36-01: Harnessing the radiation-induced local and systemic immune modulation to improve tumor control." Cancer Research 85, no. 8_Supplement_2 (2025): SY36–01—SY36–01. https://doi.org/10.1158/1538-7445.am2025-sy36-01.

Full text

Abstract:

Abstract Radiation Therapy (RT) is a highly effective anti-cancer treatment that is delivered to over half of all cancer patients. In the last century the major research focus was aimed at investigating how the direct cytotoxic effects of RT on cancer cells induced irreparable DNA damage and the determinants of intrinsic radiosensitivity. More recently the immunomodulatory effects of RT on both the immune effector cells within tumor microenvironment (TME) as well as within the surrounding normal tissue have been increasingly recognized. Despite recent technological advances in RT delivery with

APA, Harvard, Vancouver, ISO, and other styles

37

Werner, Jens M., Michael Damian, Stefan A. Farkas, Hans J. Schlitt, Edward K. Geissler, and Matthias Hornung. "Murine DX5+NKT Cells Display Their Cytotoxic and Proapoptotic Potentials against Colitis-Inducing CD4+CD62Lhigh T Cells through Fas Ligand." Journal of Immunology Research 2018 (September 30, 2018): 1–8. http://dx.doi.org/10.1155/2018/8175810.

Full text

Abstract:

Introduction. It has been previously shown that immunoregulatory DX5+NKT cells are able to prevent colitis induced by CD4+CD62Lhigh T lymphocytes in a SCID mouse model. The aim of this study was to further investigate the underlying mechanism in vitro. Methods. CD4+CD62Lhigh and DX5+NKT cells from the spleen of Balb/c mice were isolated first by MACS, followed by FACS sorting and cocultured for up to 96 h. After polyclonal stimulation with anti-CD3, anti-CD28, and IL-2, proliferation of CD4+CD62Lhigh cells was assessed using a CFSE assay and activity of proapoptotic caspase-3 was determined by

APA, Harvard, Vancouver, ISO, and other styles

38

Yang, Fu Yuan, Rui Chen, Xiaohu Zhang, et al. "Preconditioning Enhances the Therapeutic Effects of Mesenchymal Stem Cells on Colitis Through PGE2-Mediated T-Cell Modulation." Cell Transplantation 27, no. 9 (2018): 1352–67. http://dx.doi.org/10.1177/0963689718780304.

Full text

Abstract:

Mesenchymal stem cell (MSC)-based cell therapy has been demonstrated as a promising strategy in the treatment of inflammatory bowel disease (IBD), which is considered an immune disease. While the exact mechanisms underlying the therapeutic effect of MSCs are still unclear, MSCs display anti-inflammatory and immunomodulatory effects by interacting with various immunoregulatory cells. Our previous studies have shown that MSCs can be preconditioned and deconditioned with enhanced cell survival, differentiation and migration. In this study, we evaluated the effect of preconditioning on the immunor

APA, Harvard, Vancouver, ISO, and other styles

39

Kambachokova, Z. A., M. A. Khamurzova, R. M. Aramisova, et al. "Immunopathogenetic Disorders in Patients with Herpesvirus Infections." Antibiotics and Chemotherapy 65, no. 9-10 (2020): 28–31. http://dx.doi.org/10.37489/0235-2990-2020-65-9-10-28-31.

Full text

Abstract:

Immunological disorders were studied in 68 patients with herpesvirus infections (41 women and 27 men) aged 18 to 55 years. All patients were examined clinically, also laboratory tests were conducted during the period of exacerbation and clinical remission. Patients with herpesvirus infections showed a significant decrease in the relative number of CD3+, CD4+ T-lymphocytes and their subpopulations during exacerbation of herpes infection. A decrease in the content of CD 3+, CD4+ T-cells during exacerbation of the disease was associated with an increase in CD8+ T-lymphocytes. The immunoregulatory

APA, Harvard, Vancouver, ISO, and other styles

40

Kambachokova, Z. A., M. A. Khamurzova, R. M. Aramisova, et al. "Immunopathogenetic Disorders in Patients with Herpesvirus Infections." Antibiotics and Chemotherapy 65, no. 9-10 (2020): 28–31. http://dx.doi.org/10.37489/0235-2990-2020-65-9-10-28-31.

Full text

Abstract:

Immunological disorders were studied in 68 patients with herpesvirus infections (41 women and 27 men) aged 18 to 55 years. All patients were examined clinically, also laboratory tests were conducted during the period of exacerbation and clinical remission. Patients with herpesvirus infections showed a significant decrease in the relative number of CD3+, CD4+ T-lymphocytes and their subpopulations during exacerbation of herpes infection. A decrease in the content of CD 3+, CD4+ T-cells during exacerbation of the disease was associated with an increase in CD8+ T-lymphocytes. The immunoregulatory

APA, Harvard, Vancouver, ISO, and other styles

41

Khrushch, V. І., H. V. Pavlenko, V. V. Shukhtin, and І. N. Shukhtina. "THE STATE OF HOMEOSTASIS IN PATIENTS WITH INFECTIOUS ECZEMA." Likarska sprava, no. 4 (June 16, 2019): 8–15. http://dx.doi.org/10.31640/jvd.4.2019(2).

Full text

Abstract:

The article is devoted to the study of the state of homeostasis systems in patients with infectious eczema and the establishment of the relationship of the hemostatic system and immune status in the patient’s body. Examination of 108 patients with infectious eczema aged 18 to 65 years living in the southern region of Ukraine showed hypercoagulation changes in the hemostatic system and immune imbalance, which depend on the severity of the disease and play an important pathogenetic role in the onset and progression of this pathology. We have established close pathogenetic mechanisms of the relat

APA, Harvard, Vancouver, ISO, and other styles

42

Mao, Jing-Wei, Yu-Shuang Huang, Hai-Ying Tang, Jian Bi, Yan-Fei Liu, and Ying-De Wang. "Flt3/Flt3L Participates in the Process of Regulating Dendritic Cells and Regulatory T Cells in DSS-Induced Colitis." Gastroenterology Research and Practice 2014 (2014): 1–6. http://dx.doi.org/10.1155/2014/483578.

Full text

Abstract:

The immunoregulation between dendritic cells (DCs) and regulatory T cells (T-regs) plays an important role in the pathogenesis of ulcerative colitis (UC). Recent research showed that Fms-like tyrosine kinase 3 (Flt3) and Flt3 ligand (Flt3L) were involved in the process of DCs regulating T-regs. The DSS-induced colitis model is widely used because of its simplicity and many similarities with human UC. In this study, we observe the disease activity index (DAI) and histological scoring, detect the amounts of DCs and T-regs and expression of Flt3/Flt3L, and investigate Flt3/Flt3L participating in

APA, Harvard, Vancouver, ISO, and other styles

43

Malsagova, Kristina A., Tatiana A. Astrelina, Evgenii I. Balakin, et al. "Influence of Sports Training in Foothills on the Professional Athlete’s Immunity." Sports 11, no. 2 (2023): 30. http://dx.doi.org/10.3390/sports11020030.

Full text

Abstract:

Neuroplasticity and inflammation play important part in the body’s adaptive reactions in response to prolonged physical activity. These processes are associated with the cross-interaction of the nervous and immune systems, which is realized through the transmission of signals from neurotransmitters and cytokines. Using the methods of flow cytometry and advanced biochemical analysis of blood humoral parameters, we showed that intense and prolonged physical activity at the anaerobic threshold, without nutritional and metabolic support, contributes to the development of exercise-induced immunosup

APA, Harvard, Vancouver, ISO, and other styles

44

Мухамедов, Б. И., И. М. Мухамедов, Ж. А. Ризаев, Э. В. Колдарова, and А. Ш. Алиев. "Evaluation of Indicators of the Immune System in Patients Suffering from Chronic Viral Hepatitis B." Дерматовенерология Косметология 9, no. 2 (2023): 197–202. http://dx.doi.org/10.34883/pi.2023.9.2.017.

Full text

Abstract:

Проведен анализ показателей неспецифической и специфической резистентности у пациентов с хроническим вирусным гепатитом В. Представлены относительные показатели СD3 и CD19 регулярных субпопуляций Т-звена иммунитета (CD4 и CD8), N-лимфоцитов, иммунорегуляторного индекса (CD4/CD8). После лечения бификолом на фоне традиционной терапии у пациентов с хроническим вирусным гепатитом В было отмечено, что все показатели клеточного и гуморального иммунитета, а также параметры неспецифической резистентности были достоверно выше, чем у пациентов, не получавших пробиотик. The analysis of indicators of nons

APA, Harvard, Vancouver, ISO, and other styles

45

Xie, Anqi, Hao Wan, Lei Feng, Boyun Yang, and Yiqun Wan. "Protective Effect of Anoectochilus formosanus Polysaccharide against Cyclophosphamide-Induced Immunosuppression in BALB/c Mice." Foods 12, no. 9 (2023): 1910. http://dx.doi.org/10.3390/foods12091910.

Full text

Abstract:

In this study, Anoectochilus formosanus polysaccharide (AFP) was acquired a via water extraction and alcohol precipitation method. The immunoregulatory activity of AFP was first evaluated on cyclophosphamide (Cy)-treated mice. Galacturonic acid, glucose and galactose were confirmed to be the main components of AFP. AFP demonstrated the ability to stimulate the production of TNF-α and IL-6 in RAW 264.7 macrophages. Not surprisingly, the activation of the NF-κB signaling pathway by AFP was validated via Western blot analysis. Furthermore, AFP could alleviate Cy-induced immunosuppression, and sig

APA, Harvard, Vancouver, ISO, and other styles

46

Grushina, T. I., E. A. Melnikova, and Z. M. Mirkhaidarova. "ACUPUNCTURE IN ADULT PATIENTS WITH OTITIS MEDIA WITH EFFUSION." Russian Journal of Physiotherapy, Balneology and Rehabilitation 17, no. 2 (2018): 86–91. http://dx.doi.org/10.18821/1681-3456-2018-17-2-86-91.

Full text

Abstract:

The basis of conservative treatment of patients with otitis media with effusion is pharmacotherapy which can increased by acupuncture. Under observation were 64 patients aged 20 to 60 years with unilateral otitis media with effusion in the secretory stage, a duration of disease of more than 1 month and the presence of conductive hearing loss. Patients were divided by simple randomization into two comparable groups: group 1 received basic pharmacotherapy within 14 days, group 2 in addition to pharmacotherapy received 7 sessions of acupuncture according to the developed method using of general a

APA, Harvard, Vancouver, ISO, and other styles

47

Vasilenko, Vladimir S., Nazar D. Mamiev, Yuliya B. Semenova, and Ekaterina B. Karpovskaya. "The use of whole-body cryotherapy for increasing the stress resistance of female athletes in group types of gymnastics." Pediatrician (St. Petersburg) 12, no. 2 (2021): 43–52. http://dx.doi.org/10.17816/ped12243-52.

Full text

Abstract:

Background. Representatives of complex coordination sports are most susceptible to psychoemotional stress, since they demonstrate high sports results already at a young age. The tightening of anti-doping control has significantly reduced the possibility of using pharmacological and biologically active drugs to speed up the recovery of athletes. Against this background, in sports medicine, more attention is paid to the use of non-drug methods to improve performance and recovery in athletes. Aim to study the efficiency of the introduction of whole-body cryotherapy in the training process o

APA, Harvard, Vancouver, ISO, and other styles

48

Tkachenko, P. I., S. O. Bilokon, N. M. Lokhmatova, O. B. Dolenko, K. Yu Rezvina, and Yu V. Popelo. "THE IMMUNOCOMPETENCE OF THE LYMPHOCYTIC POOL OF PERIPHERAL BLOOD IN ACUTE PURULENT LYMPHADENITIS IN CHILDREN." Ukrainian Dental Almanac, no. 2 (June 19, 2019): 14–19. http://dx.doi.org/10.31718/2409-0255.2.2019.03.

Full text

Abstract:

The substantial prevalence of different nosological forms of lymphadenitis in children is due to morpho-functional immaturity and age-related features of the structural components of the lymph node. The lymphatic system in children under 6 years of age is well developed, however, their immune competence is not perfect. Therefore, most often lymphadenitis of neodontogenic origin occurs at this age when the immune response of the organism to a significant number of bacterial and viral stimuli is insufficient for its reliable protection. The purpose of the work was to study the immunocompet

APA, Harvard, Vancouver, ISO, and other styles

49

Liu, Tao, Jun Zhao, Long Ma, Yusong Ding, and Deqi Su. "Hepatoprotective Effects of Total Triterpenoids and Total Flavonoids fromVitis viniferaL against Immunological Liver Injury in Mice." Evidence-Based Complementary and Alternative Medicine 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/969386.

Full text

Abstract:

Suosuo grape (the fruits ofVitis viniferaL) has been used for prevention and treatment of liver diseases in Uighur folk medicine in China besides its edible value. In this study, the hepatoprotective effects of total triterpenoids (VTT) and total flavonoids (VTF) from Suosuo grape were evaluated in Bacille-Calmette-Guerin- (BCG-) plus-lipopolysaccharide- (LPS-) induced immunological liver injury (ILI) in mice. Various dose groups (50, 150, and 300 mg/kg) of VTT and VTF alleviated the degree of liver injury of ILI mice, effectively reduced the BCG/LPS-induced elevated liver index and spleen ind

APA, Harvard, Vancouver, ISO, and other styles

50

Vashchenko, V. "POSSIBILITIES OF CORRECTING CELLULAR-HUMORAL IMMUNE DISORDERS AND CYTOKINE STATUS IN HIGH-RISK PREGNANT WOMEN FOR THE DEVELOPMENT OF PREECLAMPSIA." Neonatology, surgery and perinatal medicine 8, no. 4(50) (2023): 105–10. http://dx.doi.org/10.24061/2413-4260.xiii.4.50.2023.15.

Full text

Abstract:

The development of pre-eclampsia is associated with immunological interactions between the foreign maternal and fetaltissues, which are characterized by a predominance of the infl uence of type 1 T-helper cells, leading to increased production of highly aggressive pro-infl ammatory cytokines. However, the mechanism of cellular- humoral immune and cytokine changes leading to the manifestation of pre-eclampsia is not fully understood and no corrective measures have been developed.Purpose. To investigate the changes in the cellular- humoral immunity and cytokine profi le in a cervical mucus of pr

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!