Relevant bibliographies by topics / Impaired PTT

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Impaired PTT'

Author: Grafiati
Published: 5 June 2025
Last updated: 2 August 2025

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Journal articles on the topic "Impaired PTT"

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Israelsson, Kjell-Erik, Renata Bogo, and Erik Berninger. "Reliability in Hearing Threshold Prediction in Normal-Hearing and Hearing-Impaired Participants Using Mixed Multiple ASSR." Journal of the American Academy of Audiology 26, no. 03 (2015): 299–310. http://dx.doi.org/10.3766/jaaa.26.3.9.

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Background and Purpose: The rapidly evolving field of hearing aid fitting in infants requires rapid, objective, and highly reliable methods for diagnosing hearing impairment. The aim was to determine test-retest reliability in hearing thresholds predicted by multiple auditory steady-state response (ASSRthr) among normal-hearing (NH) and hearing-impaired (HI) adults, and to study differences between ASSRthr and pure-tone threshold (PTT) as a function of frequency in each participant. ASSR amplitude versus stimulus level was analyzed to study ASSR growth rate in NH and HI participants, especiall
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Qian, Hai, Lucas Matt, Mingxu Zhang та ін. "β2-Adrenergic receptor supports prolonged theta tetanus-induced LTP". Journal of Neurophysiology 107, № 10 (2012): 2703–12. http://dx.doi.org/10.1152/jn.00374.2011.

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The widespread noradrenergic innervation in the brain promotes arousal and learning by molecular mechanisms that remain largely undefined. Recent work shows that the β2-adrenergic receptor (β2AR) is linked to the AMPA-type glutamate receptor subunit GluA1 via stargazin and PSD-95 (Joiner ML, Lise MF, Yuen EY, Kam AY, Zhang M, Hall DD, Malik ZA, Qian H, Chen Y, Ulrich JD, Burette AC, Weinberg RJ, Law PY, El-Husseini A, Yan Z, Hell JW. EMBO J 29: 482–495, 2010). We now demonstrate that the β2AR plays a prominent role in long-term potentiation (LTP) induced by a train of 900 stimuli at 5 Hz (prol
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Sanjay, Nath Jha, Kumar Jha Rajesh, and Jha Vinayanand. "Clinical Study on Evaluation of Protein Tolerance Test as Marker for Early Renal Dysfunction in Type 2 Diabetes Mellitus." International Journal of Pharmaceutical and Clinical Research 15, no. 5 (2023): 847–52. https://doi.org/10.5281/zenodo.12582575.

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<strong>Background:</strong>&nbsp;A protein tolerance test can be highly helpful in selecting individuals who are most likely to benefit from an aggressive intervention by detecting incipient renal failure in those with normal GFR and serum creatinine values. This is crucial when assessing high-risk individuals including diabetics, people who have just undergone a kidney transplant, and people with polycystic kidney disease. PTT can be used to accurately predict the prognosis of a progressing renal disease and to evaluate the borderline renal donor. To demonstrate the value of the tubular stre
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Osokin, Roman, Ekaterina Komarova, Igor Aboyan, et al. "Intrarenal renin-angiotensin system in hypertensive patients with localized kidney cancer." Journal of Clinical Oncology 38, no. 15_suppl (2020): e17069-e17069. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e17069.

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e17069 Background: In the last decade, the relationship between arterial hypertension and the risk of developing kidney cancer has been pointed out. Some studies have shown that the metabolic imbalance of the components of the renal renin-angiotensin system (RAS) is associated with the development and progression of kidney cancer. Aim: To study the state of RAS in tumor and peritumoral tissues in hypertensive patients with kidney cancer. Methods: In patients with localized kidney cancer T1N0M0 and grade I-II arterial hypertension without special treatment (n = 40; KC + AH) in the samples of tu
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Federici, Marco Orsini, Evangelia Mourvaki, Piero Ferolla, et al. "Impaired endothelial antithrombotic activity following short-term interruption of continuous subcutaneous insulin infusion in type1 diabetic patients." Thrombosis and Haemostasis 98, no. 09 (2007): 635–41. http://dx.doi.org/10.1160/th07-03-0201.

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SummaryReview of literature has shown an increased rate of thrombotic complications in diabetic patients with frequent episodes of hyperketonemia. However, the mechanisms by which ketosis promotes vascular disease in diabetic patients are unclear.It was the aim of this study to investigate early changes in haemostatic parameters and oxidative stress markers during the hyperketonemic status which follows the interruption of continuous subcutaneous insulin infusion (CSII) in type I diabetic patients. Eight CSII-treated type I diabetic patients underwent a 4-hour pump arrest. Blood glucose, insul
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Jabber, Halla A., Jaffar N. Alsaidissa, and Haithem A. Al-Rubaie. "The relationship between obesity and plasma level of factor V and fibrinogen." Journal of the Faculty of Medicine Baghdad 59, no. 1 (2017): 53–59. http://dx.doi.org/10.32007/jfacmedbagdad.591162.

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Background: Obesity is a medical condition in which excess body fat has accumulated to the extent that it has an adverse effect on health. . It measured by BMI (body mass index), obesity is considered when the BMI is ≥ 30 kg/m2. It increases the risk of coronary heart disease, Diabetes Mellitus and Cancer. Chronic inflammation and impaired fibrinolysis in obesity may induce thrombosis.&#x0D; Aim of study: assess the effect of BMI (body mass index) on plasma level of Factor V and fibrinogen in obese and normal weight subjects.&#x0D; Methods: This study was started on December 2015 and completed
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Zangari, Maurizio, Jose Guerrero, Federica Cavallo, et al. "Coagulation-Related Effect of Bortezomib Treatment in Patients with Relapsed or Refractory Multiple Myeloma." Blood 110, no. 11 (2007): 2733. http://dx.doi.org/10.1182/blood.v110.11.2733.2733.

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Abstract Proteasomes inhibitors have been recently identified as potential agents, which can influence processes leading to thrombosis. We have previously reported a reduced incidence of deep vein thrombosis (DVT) in 69 patients enrolled in Total Therapy III and treated with (B), dexamethasone, thalidomide, cisplatin and doxorubicin with prophylactic anticoagulation. Patients with relapse MM, not previously exposed to B with normal baseline coagulation parameters (PT, PTT fibrinogen and platelet count) were eligible for the study. Except for the two PCR-based genotyping assays Factor V Leiden
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Rezazadeh, Arash, Sandra C. Hollensead, Damian A. Laber, and Goetz H. Kloecker. "Intracranial Hemorrhage in a Patient with Osteogenesis Imperfecta Due to Inherited and Acquired Platelet Dysfunction." Blood 108, no. 11 (2006): 3960. http://dx.doi.org/10.1182/blood.v108.11.3960.3960.

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Abstract A 42 year-old man with Osteogenesis Imperfecta (OI) had three episodes of spontaneous Subdural Hematoma (SH) after binge drinking. There is no remote history of abnormal bleeding or easy bruising despite multiple fractures. Medications included Aspirin (ASA). The first and second SH occurred within the preceding year and were treated conservatively. The third SH occurred while on ASA and drinking more than 500cc liquor/day. The Platelet Function Assay (PFA-100) was significantly abnormal (see table). After platelet transfusions the SH was surgically evacuated without complications. An
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Holden, Maureen K., Kathleen M. Gill, and Marie R. Magliozzi. "Gait Assessment for Neurologically Impaired Patients." Physical Therapy 66, no. 10 (1986): 1530–39. http://dx.doi.org/10.1093/ptj/66.10.1530.

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Savvas, Steven M., and Stephen J. Gibson. "Treating pain in patients with impaired cognition." Pain Management 4, no. 5 (2014): 335–38. http://dx.doi.org/10.2217/pmt.14.27.

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Dissertations / Theses on the topic "Impaired PTT"

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Pepler, Anna. "Cochlear dead regions in hearing-impaired adults." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/cochlear-dead-regions-in-hearingimpaired-adults(59f1eb35-d113-4885-8b27-013862b88717).html.

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Cochlear dead regions (DRs) are areas in the cochlea where inner hair cells and/or neurones are functioning so poorly that a sound that causes peak basilar membrane motion in that region is more efficiently detected via off-frequency listening. The Threshold Equalising Noise (TEN) test is a clinical test procedure for detecting DRs. Psychophysical Tuning Curves (PTCs) can be used to identify the boundary frequency of the DR although the clinical importance of doing this has yet to be determined. Some studies have suggested that the reduction of amplification well inside the DR may be beneficia
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E'Silva, Julie D. M. "The perceptual thinking processes of victims of repetitive armed robberies in the workplace : a Rorschach study." Diss., 2005. http://hdl.handle.net/2263/30046.

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The current study describes the impact of trauma on the perceptual thinking processes of participants who have sustained repeated criminal victimisation in South Africa. Fifteen adult males, (mean age 40.73 years) participated voluntarily in this descriptive study. The Rorschach Inkblot Method (RIM) is the psychometric instrument used to describe the participants and Exner’s Comprehensive System (CS) is the method of interpretation employed. The Perceptual Thinking Index (PTI) is the cluster of variables selected to describe each participant’s level of reality testing and perceptual functionin
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Books on the topic "Impaired PTT"

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Beattie, R. Mark, Anil Dhawan, and John W.L. Puntis. Acute liver failure. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198569862.003.0063.

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Definition 476Aetiology 476Therapy 480Complications 480Transplantation 484Liver support system 484Prognosis 485Acute liver failure (ALF) in children is defined as ‘a rare multisystem disorder in which severe impairment of liver function, with or without encephalopathy, occurs in association with hepatocellular necrosis in a patient with no recognized underlying chronic liver disease’. Liver function is considered severely impaired if prothrombin time (PT) is &gt;15 s or international normalized ratio (INR) is &gt;1.5 and not corrected by vitamin K, in the presence of hepatic encephalopathy (HE
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Rafii, Michael S. Alzheimer’s Disease. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0016.

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Alzheimer’s disease (AD) is the most common cause of dementia worldwide, and is characterized by a protracted asymptomatic phase estimated to begin approximately 15 to 20 years. Clinically, AD initially manifests itself by progressive memory impairment, specifically, a loss of episodic memory function characterized by impaired free recall that does not improve with cueing. This is followed by a gradual decline in other cognitive domains leading to functional dependency, which essentially defines the dementia phase of the illness and has been the cornerstone of diagnostic criteria. About 50% of
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Das, Veena. Textures of the Ordinary. Fordham University Press, 2020. http://dx.doi.org/10.5422/fordham/9780823287895.001.0001.

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Textures of the Ordinary: Doing Anthropology after Wittgenstein is an exploration of everyday life in which anthropology finds a companionship with philosophy. Based on two decades of ethnographic work among low-income urban families in India, Das shows how the notion of texture allows her to align her ethnography with stunning anthropological moments in Wittgenstein and Cavell as well as in literary texts from India. Das poses a compelling question—how might we speak of a human form of life when the very idea of the human has been put into question? The response to this question, Das argues,
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Hadley, John. Animal Property Rights. The Rowman & Littlefield Publishing Group, 2015. https://doi.org/10.5040/9781666985054.

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Animal Property Rights: A Theory of Habitat Rights for Wild Animals represents the first attempt to extend liberal property rights theory across the species barrier to animals. It broadens the traditional focus of animal rights beyond basic rights to life and bodily integrity to rights to the natural areas in which animal reside. John Hadley argues that both proponents of animal rights and environmentalists ought to support animal property rights because protecting habitat promotes ecological values and helps to ensure animals live free from human interference. Hadley’s focus is pragmatist – h
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Matthies-Boon, Vivienne. Breaking Intersubjectivity. The Rowman & Littlefield Publishing Group, 2022. https://doi.org/10.5040/9798881810023.

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Trauma is commonly understood as Post-Traumatic Stress Disorder (PTSD). Yet, as this book explains, the concept of PTSD is problematic because it is rooted in a solipsist Philosophy of the Subject. Within such a philosophical perspective, it is not only impossible to account for trauma’s causality, but the traumatic ‘event’ is also prioritised over traumatic social and political structures as trauma is depoliticised as an (individual) internal cognitive object. Rooted in Frankfurt School critical theory, this book thus urges us to rethink the concept of trauma: trauma should not be understood
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Book chapters on the topic "Impaired PTT"

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Fripp, Jurgen, Pierrick Bourgeat, Parnesh Raniga, et al. "MR-Less High Dimensional Spatial Normalization of 11C PiB PET Images on a Population of Elderly, Mild Cognitive Impaired and Alzheimer Disease Patients." In Medical Image Computing and Computer-Assisted Intervention – MICCAI 2008. Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-85988-8_53.

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Nock, Berthold A., and Theodosia Maina. "Theranostic Radiopeptides in Nuclear Oncology: Design, Preclinical Screening, and Clinical Translation." In Beyond Becquerel and Biology to Precision Radiomolecular Oncology: Festschrift in Honor of Richard P. Baum. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-33533-4_22.

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AbstractCancer theranostics is an emerging and exciting field in nuclear medicine, whereby suitably designed radionuclide carriers, after injection to patients, seek and specifically interact with biomolecular targets overexpressed on cancer cells. When a diagnostic radionuclide is applied, molecular imaging with SPECT (gamma emitter) or PET (positron emitter) will reveal tumor lesions, allowing for initial diagnosis and assessment of disease spread and progression. Hence, molecular imaging represents a reliable tool for patient stratification, dosimetry and planning of therapy that follows ne
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Laureys, S., M. E. Faymonville, S. Goldman, et al. "Impaired Cerebral Connectivity in Vegetative State." In Physiological Imaging of the Brain with PET. Elsevier, 2001. http://dx.doi.org/10.1016/b978-012285751-5/50050-8.

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C. G, Mallamma, Varalakshmi B. D, Nagapushpa K. P, and Anuradha U. "SMART NAVIGATION ASSISTANCE SYSTEM FOR THE VISUALLY IMPAIRED." In Futuristic Trends in IOT Volume 3 Book 5. Iterative International Publisher, Selfypage Developers Pvt Ltd, 2024. http://dx.doi.org/10.58532/v3bgio5p2ch4.

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There are several hassles in daily life for visually challenged people. In light of this, it is very important to focus on the needs of those who are visually impaired. To help people who are vision impaired to enjoy normal lives, researchers approach the issue from a variety of angles. The white cane is the support system and it enables a sense of being free, independent and self-assured. They can easily take care of their daily tasks thanks to the proposed smart cane's design, which includes an obstacle detection module, heat detection, water detection, light detection, pit and staircase det
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Landman-Parker, Judith, and Françoise Montravers. "Hodgkin LymphomaModern Management of Children and Young Adults." In Oxford Textbook of Cancer in Children. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198797210.003.0019.

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Hodgkin lymphoma (HL) is the most common cancer in adolescence and represents 15% of all cases of cancer in children and adolescents. In three decades, HL has become a highly curable lymphoid malignancy with an expected survival rate at ten years of around 90–93%. Further refinements of treatment strategy are needed in order to improve treatment results in relapsed and refractory patients and to reduce long-term morbidity of therapy, mainly secondary malignancies, cardiovascular early morbidity, and impaired fertility. Progress in imaging definition of involvement based on fluorodeoxyglucose-p
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Cornett Alex and Kuziemsky Craig. "Information Issues and Contexts that Impair Team Based Communication Workflow: A Palliative Sedation Case Study." In Studies in Health Technology and Informatics. IOS Press, 2015. https://doi.org/10.3233/978-1-61499-574-6-107.

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Implementing team based workflows can be complex because of the scope of providers involved and the extent of information exchange and communication that needs to occur. While a workflow may represent the ideal structure of communication that needs to occur, information issues and contextual factors may impact how the workflow is implemented in practice. Understanding these issues will help us better design systems to support team based workflows. In this paper we use a case study of palliative sedation therapy (PST) to model a PST workflow and then use it to identify purposes of communication
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Blakey, Hannah, and Kate Bramham. "Advanced renal disease/renal impairment." In Practical management of the pregnant patient with rheumatic disease, edited by Karen Schreiber, Eliza Chakravarty, and Monika Østensen. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780198845096.003.0005.

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There is an increased incidence of chronic kidney disease (CKD) in patients with underlying rheumatic disease. For a proportion of patients, CKD is diagnosed for the first time in pregnancy through routine antenatal blood and urine testing. Pregnancy places increased physiological demand on the kidneys, and women with CKD have increased risks of adverse pregnancy outcomes, including pre-eclampsia (PET), pre-term delivery, and low birth weight babies. These risks increase incrementally with declining baseline renal function. Thorough pre-conception counselling and regular antenatal review by te
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Dondero, Franco, Loredana Gandini, Francesco Lombardo, and Andrea Lenzi. "Immunological infertility." In Oxford Textbook of Endocrinology and Diabetes. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199235292.003.9100.

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Immunological infertility is the presence, in one or both partners, of an antisperm immune reaction capable of interfering with fertility variables. In about 8–10% of these couples the immunological phenomenon is on the male side, causing ‘male immunological infertility’ (1). Since the first demonstration that a significant number of infertile men show an autoimmunity to sperm, experiments have suggested that antisperm antibodies (ASA) can interfere with the fertilizing ability of spermatozoa (2). ASA can act negatively on the motility of spermatozoa in semen, on their ability to pass through
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Pei, Zhe, Kuo-Chieh Lee, Amber Khan, and Hoau-Yan Wang. "Brain Insulin Resistance, Nitric Oxide and Alzheimer’s Disease Pathology." In The Role of Nitric Oxide in Type 2 Diabetes. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/9789815079814122010014.

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Alzheimer’s disease (AD) is a devastating age-related neurodegenerative disease characterized by progressive pathological changes and functional and cognitive impairments. Brain insulin resistance appears to contribute significantly to the pathology and cognitive deficits among several pathological mechanisms. Brain insulin resistance has been demonstrated in animal models of AD and postmortem human brain tissue from patients with AD dementia. Studies conducted in AD models and humans suggest attenuating brain insulin resistance by agents such as glucagon-like peptide1 (GLP-1) analogs and smal
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Manimekalai, K., and A. Kavitha. "Filtering Techniques for Removing Noise From ECG Signals." In Advances in Computing Communications and Informatics. BENTHAM SCIENCE PUBLISHERS, 2023. http://dx.doi.org/10.2174/9789815079005123050010.

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Electrocardiogram (ECG) records cardiac electrical signal to check for various heart problems. However, it can be impaired by noise. Therefore, ECG signal denoising is a significant pre-processing step that reduces noise and emphasizes the characteristic waves in the ECG data. The frequency range of a simple ECG is usually between 0.5 Hz and 100 Hz. When processing the ECG signal, artifact elimination is the most important resource since artifacts in ECG signal impede the diagnosis of disorders. This work uses MATLAB to reduce noise by applying low pass, high pass, and derivative pass filters.
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Conference papers on the topic "Impaired PTT"

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Teitel, J. M., M. B. Garvey, and J. J. Freedman. "THE ENDOTHELIAL CELL AS THE SII$ OF THE FACTOR VIII BYPASSING ACTIVITY OF PROTHROMBIN COMPLEX CONCENTRATE (PCC)." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644731.

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PCC is used empirically for its factor VIII (FVIII) bypassing activity in hemophiliacs with inhibitors to FVIII. The effect of of PCC on plasma coagulation tests is variable and is not predictive of clinical response. We are testing the hypothesis that bypass activity is expressed locally at the vessel wall, which functions as a procoagulant surface at times of hemostatic stress. Monolayer cultures of umbilical vein endothelial cells (EC) were incubated for 1 hour with commerical PCC (1 u/ml), and then extensively washed to remove fluid phase PCC components. Ellagic acid-activated PTT determin
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Schorer, Anna E., and Kathleen V. Watson. "THE "LUPUS ANTICOAGULANT" INDUCES FUNCTIONAL CHANGES IN ENDOTHELIAL CELLS AND PLATELETS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643656.

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The presence of the "lupus anticoagulant" (LA) predicts a clinical syndrome of excessive arterial, venous and microvascu-lar thrombosis. LA is an antibody which reacts with negatively charged phospholipid (PL) species in vitro. Since PL is involved in many aspects of the regulation of thrombosis, we postulated that LA might modify one or more of the membrane-(PL-dependent reactions of platelets and endothelial cells (EC). Blood samples from 20 patients with a history of thrombosis were tested for the presence of LA (kaolin PTT) and titres determined. LA-positive (LA+) sera and plasma were comp
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Bhatlawande, Shripad, Manjunatha Mahadevappa, and Jayanta Mukhopadhyay. "Way-finding Electronic Bracelet for visually impaired people." In 2013 IEEE Point-of-Care Healthcare Technologies (PHT). IEEE, 2013. http://dx.doi.org/10.1109/pht.2013.6461334.

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Weiss, H. J., V. T. Turitto, and H. R. Baumgartner. "FACTORS INFLUENCING FIBRIN DEPOSITION ON SUBENDOTHELIUM." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642950.

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During the past several years, we have initiated studies to determine the role of plasma factors and platelets, and the properties of the blood vessel, which influence the activation of the coagulation mechanism on the subendothelium. Studies were performed by exposing everted segments of de-endothelialized rabbit aorta, mounted in a perfusion chamber, to non-anticoagulated human blood for 5 to 10 minutes under a range of flow conditions, and measuring fibrin and platelet deposition on the subendothelium, and fibrinopepstide A (FPA) levels in post-chamber blood. In normal subjects, platelet de
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Mikić, Miomir, Sandra Milutinović, Radmilo Rajković, and Milenko Jovanović. "Impact on the environment and reclamation of the landfill Saraka, Veliki Krivelj." In Proceedings - 55th International October Conference on Mining and Metallurgy, Kladovo, 15-17 October 2024. Mining and Metallurgy Institute, Bor, 2024. https://doi.org/10.5937/ioc24037m.

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The consequence of increase in the exploitation capacity of copper ore at the open pit "Veliki Krivelj" is the expansion of the Saraka landfill. The result of landfill expansion is a degradation of the surrounding land. The impact on the quality of the environment as a result of these works is greatly impaired. In order to protect it, it is necessary to intervene in such a way that the neglected areas of the Saraka landfill are recultivated as soon as possible.
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Speck, I., S. Arndt, PT Meyer, and L. Frings. "Investigation of the auditory pathway in asymmetric hearing-impaired patients with FDG-PET." In Abstract- und Posterband – 90. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn – Digitalisierung in der HNO-Heilkunde. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1686510.

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Fripp, J., P. Bourgeat, O. Acosta, et al. "Generative atlases and atlas selection for C11-PIB PET-PET registration of elderly, mild cognitive impaired and Alzheimer disease patients." In 2008 5th IEEE International Symposium on Biomedical Imaging (ISBI 2008). IEEE, 2008. http://dx.doi.org/10.1109/isbi.2008.4541206.

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Randi, A. M., E. Sacchi, and M. Cattaneo. "ORALLY ADMINISTERED VITAMIN B PROLONGS THE BLEEDING TIME AND INHIBITS PLATELET AGGREGATION IN HUMAN VOLUNTEERS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643446.

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It is known that mM concentrations of vitamin B6 inhibit human platelet aggregation and fibrin formation in vitro. There are very few and controversial data on the ex vivo effects of vitamin B6 on hemostatic parameters. We evaluated the effects of oral administration of vitamin B6 on bleeding time (BT), fibrin formation, platelet aggregation (PA) and the release reaction (RR). Vitamin B6 300 mg/day p.o., was given to 18 healthy volunteers (8 M, 10 F, aged 23-35) for 8 days. BT was measured before the first dose (Baseline), 2 hr after the first (Day 1) and the last dose (Day 8). In 7 subjects B
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Altman, Allison R., Beom Kang Huh, Abhishek Chandra, Wei-Ju Tseng, Ling Qin, and X. Sherry Liu. "3D In Vivo Bone Dynamic Imaging of PTH’s Anabolic Action." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14671.

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Aging shifts bone remodeling toward a negative balance between bone formation and resorption, causing bone loss and increased fracture risk. Anti-resorptive agents are commonly used to inhibit bone resorption and stabilize bone mass. While they are effective to prevent further bone loss, there is also a great need for anabolic agents which can reverse bone deterioration and regain lost skeletal integrity. Intermittent parathyroid hormone (PTH) treatment is the only FDA-approved anabolic treatment for osteoporosis, which greatly stimulates bone formation. Combined therapy of anti-resorptive dru
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Singhal, Manu, Ahmed Al-Abri, Thomas Jarratt, and Lang Zhan. "Petrophysical Challenges and Impact of Bitumen Quantification in Reservoir Rocks." In ADIPEC. SPE, 2024. http://dx.doi.org/10.2118/222456-ms.

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Abstract Conventional reservoirs with bitumen pose a challenge to accurately quantify its presence and impact on reservoir producibility. Due to the presence of bitumen in the reservoir, which can be in the form of pore lining, pore fill and/or pore throat blocking, reservoir connected porosity and permeability is impaired. If volume of bitumen is not correctly quantified then hydrocarbon in place, completion decisions, reservoir producibility and ultimate recovery is impacted. Basic logs often do not have sufficient contrast to differentiate bitumen from hydrocarbon in the reservoir, hence, a
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Reports on the topic "Impaired PTT"

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Cao, Xianling, Xuanyou Zhou, Naixin Xu, Songchang Chang, and Chenming Xu. Association of IL-4 and IL-10 Polymorphisms with Preterm Birth Susceptibility: A Systematic Review and Meta-Analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.4.0044.

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Review question / Objective: The aim of our systematic review and meta-analysis was to summarize the effects of IL-4 and IL-10 gene polymorphism and clarify their possible association with PTB. Condition being studied: World Health Organization (WHO) defines preterm birth (PTB) as babies born alive before 37 weeks of pregnancy are completed. The new estimates show that the prevalence of PTB during 2014 ranged from 8.7% to13.4% of all live births, about 15 million preterm babies born each year. Besides, PTB is the leading cause of death worldwide for children below 5 years of age. Babies born p
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Sionov, Edward, Nancy Keller, and Shiri Barad-Kotler. Mechanisms governing the global regulation of mycotoxin production and pathogenicity by Penicillium expansum in postharvest fruits. United States Department of Agriculture, 2017. http://dx.doi.org/10.32747/2017.7604292.bard.

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The original objectives of the study, as defined in the approved proposal, are: To characterize the relationship of CreA and LaeA in regulation of P T production To understand how PacC modulates P. expansumpathogenicity on apples To examine if other secondary metabolites are involved in virulence or P. expansumfitness To identify the signaling pathways leading to PAT synthesis Penicilliumexpansum, the causal agent of blue mould rot, is a critical health concern because of the production of the mycotoxinpatulin (PAT) in colonized apple fruit tissue. Although PAT is produced by many Penicilliums
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Sessa, Guido, and Gregory B. Martin. molecular link from PAMP perception to a MAPK cascade associated with tomato disease resistance. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7597918.bard.

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The research problem: The detection of pathogen-associated molecular patterns (PAMPs) by plant pattern recognition receptors (PRRs) is a key mechanism by which plants activate an effective immune response against pathogen attack. MAPK cascades are important signaling components downstream of PRRs that transduce the PAMP signal to activate various defense responses. Preliminary experiments suggested that the receptor-like cytoplasmickinase (RLCK) Mai5 plays a positive role in pattern-triggered immunity (PTI) and interacts with the MAPKKK M3Kε. We thus hypothesized that Mai5, as other RLCKs, fun
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Sessa, Guido, and Gregory Martin. role of FLS3 and BSK830 in pattern-triggered immunity in tomato. United States Department of Agriculture, 2016. http://dx.doi.org/10.32747/2016.7604270.bard.

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Pattern-recognition receptors (PRRs) located on the plant cell surface initiate immune responses by perceiving conserved pathogen molecules known as pathogen-associated molecular patterns (PAMPs). PRRs typically function in multiprotein complexes that include transmembrane and cytoplasmickinases and contribute to the initiation and signaling of pattern-triggered immunity (PTI). An important challenge is to identify molecular components of PRR complexes and downstream signaling pathways, and to understand the molecular mechanisms that mediate their function. In research activities supported by
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Manulis, Shulamit, Christine D. Smart, Isaac Barash, Guido Sessa, and Harvey C. Hoch. Molecular Interactions of Clavibacter michiganensis subsp. michiganensis with Tomato. United States Department of Agriculture, 2011. http://dx.doi.org/10.32747/2011.7697113.bard.

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Clavibacter michiganensis subsp. michiganensis (Cmm), the causal agent of bacterial wilt and canker of tomato, is the most destructive bacterial disease of tomato causing substantial economic losses in Israel, the U.S.A. and worldwide. The molecular strategies that allow Cmm, a Gram-positive bacterium, to develop a successful infection in tomato plants are largely unknown. The goal of the project was to elucidate the molecular interactions between Cmmand tomato. The first objective was to analyze gene expression profiles of susceptible tomato plants infected with pathogenic and endophytic Cmms
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