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1

Arnaud, Philippe. "Genomic imprinting in germ cells: imprints are under control." REPRODUCTION 140, no. 3 (2010): 411–23. http://dx.doi.org/10.1530/rep-10-0173.

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The cis-acting regulatory sequences of imprinted gene loci, called imprinting control regions (ICRs), acquire specific imprint marks in germ cells, including DNA methylation. These epigenetic imprints ensure that imprinted genes are expressed exclusively from either the paternal or the maternal allele in offspring. The last few years have witnessed a rapid increase in studies on how and when ICRs become marked by and subsequently maintain such epigenetic modifications. These novel findings are summarised in this review, which focuses on the germline acquisition of DNA methylation imprints and
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2

Smolinska-Kempisty, Katarzyna, Joanna Wolska, and Marek Bryjak. "Molecularly Imprinting Microfiltration Membranes Able to Absorb Diethyl Phthalate from Water." Membranes 12, no. 5 (2022): 503. http://dx.doi.org/10.3390/membranes12050503.

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In this study, polypropylene porous membranes with an average pore size of 1.25 µm were modified by barrier discharge plasma. Next, molecularly imprinted layers with an imprint of diethyl phthalate (DEP) ware grafted of their surface. In order to optimize the composition of the modifying mixture various solvents, the ratios of functional monomers and the cross-linking monomer as well as various amounts of phthalate were verified. It was shown that the most effective membranes were obtained during polymerization in n-octane with the participation of functional monomers in the ratio 3:7 and the
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3

Nykänen, Nooa. "Following the Old Road: Organizational Imprinting and the Regional Development of Russia." Management and Organization Review 17, no. 3 (2021): 583–616. http://dx.doi.org/10.1017/mor.2020.83.

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ABSTRACTIn this article, I draw from organizational imprinting theory to illuminate the impact of the Soviet legacy on contemporary Russian economic geography and regional policy. I argue that central coordination in the creation and regulation of Russian urban agglomerations is connected to a socialist imprinted paradigm associated with the Soviet economic regionalization model and territorial-production complexes (TPCs). I conduct a qualitative historical study to analyze the role of the foundational environment and the dynamics in the development of this imprint. I propose that this imprint
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4

O'Doherty, A. M., D. Magee, M. E. Beltman, S. Mamo, D. Rizos, and T. Fair. "88 VARIABLE DNA METHYLATION PROFILES AT IMPRINTED LOCI IN BOVINE EARLY PRE-IMPLANTATION EMBRYOS." Reproduction, Fertility and Development 25, no. 1 (2013): 192. http://dx.doi.org/10.1071/rdv25n1ab88.

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The DNA methylation imprints, at maternally imprinted gene differentially methylated regions, are established during the postnatal growth stage of oogenesis, with paternal imprints being acquired in the perinatal prospermatagonia. Murine DNA methylation marks, at imprinted loci, are widely regarded to be resistant to post-fertilization demethylation events that occur in the paternal pronucleus of the zygote and to passive demethylation of the maternally derived genomic content from cleavage to the 16-cell stage. However, the DNA methylation profile of bovine imprinted genes following fertiliza
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5

Kato, Y., W. M. Rideout, K. Hilton, S. C. Barton, Y. Tsunoda, and M. A. Surani. "Developmental potential of mouse primordial germ cells." Development 126, no. 9 (1999): 1823–32. http://dx.doi.org/10.1242/dev.126.9.1823.

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There are distinctive and characteristic genomic modifications in primordial germ cells that distinguish the germ cell lineage from somatic cells. These modifications include, genome-wide demethylation, erasure of allele-specific methylation associated with imprinted genes, and the re-activation of the X chromosome. The allele-specific differential methylation is involved in regulating the monoallelic expression, and thus the gene dosage, of imprinted genes, which underlies functional differences between parental genomes. However, when the imprints are erased in the germ line, the parental gen
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6

Vu, Hoang Yen, and A. N. Zyablov. "Determination of preservatives in liquids by piezosensors." Аналитика и контроль 26, no. 2 (2022): 134–40. http://dx.doi.org/10.15826/analitika.2022.26.2.001.

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In the current study, piezosensors based on the molecularly imprinted polyimides with imprints of potassium sorbate and sodium benzoate were obtained. Molecularly Imprinted Polymers (MIPs) were synthesized using a polyimide and a non-covalent imprinting technique. It was established that the use of 0.1 g/mL template concentration at the thermochemical stage led to the formation of the maximum number of molecular imprints on the film surface. Using the scanning force microscopy, it was found that the reference polymer film had a uniform surface with a small height difference from 1.4 to 2.6 nm
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7

Edwards, Carol A., Nozomi Takahashi, Jennifer A. Corish, and Anne C. Ferguson-Smith. "The origins of genomic imprinting in mammals." Reproduction, Fertility and Development 31, no. 7 (2019): 1203. http://dx.doi.org/10.1071/rd18176.

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Genomic imprinting is a process that causes genes to be expressed according to their parental origin. Imprinting appears to have evolved gradually in two of the three mammalian subclasses, with no imprinted genes yet identified in prototheria and only six found to be imprinted in marsupials to date. By interrogating the genomes of eutherian suborders, we determine that imprinting evolved at the majority of eutherian specific genes before the eutherian radiation. Theories considering the evolution of imprinting often relate to resource allocation and recently consider maternal–offspring interac
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8

Tunster, S. J., A. B. Jensen, and R. M. John. "Imprinted genes in mouse placental development and the regulation of fetal energy stores." REPRODUCTION 145, no. 5 (2013): R117—R137. http://dx.doi.org/10.1530/rep-12-0511.

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Imprinted genes, which are preferentially expressed from one or other parental chromosome as a consequence of epigenetic events in the germline, are known to functionally converge on biological processes that enablein uterodevelopment in mammals. Over 100 imprinted genes have been identified in the mouse, the majority of which are both expressed and imprinted in the placenta. The purpose of this review is to provide a summary of the current knowledge regarding imprinted gene function in the mouse placenta. Few imprinted genes have been assessed with respect to their dosage-related action in th
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9

MacDonald, William A. "Epigenetic Mechanisms of Genomic Imprinting: Common Themes in the Regulation of Imprinted Regions in Mammals, Plants, and Insects." Genetics Research International 2012 (February 15, 2012): 1–17. http://dx.doi.org/10.1155/2012/585024.

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Genomic imprinting is a form of epigenetic inheritance whereby the regulation of a gene or chromosomal region is dependent on the sex of the transmitting parent. During gametogenesis, imprinted regions of DNA are differentially marked in accordance to the sex of the parent, resulting in parent-specific expression. While mice are the primary research model used to study genomic imprinting, imprinted regions have been described in a broad variety of organisms, including other mammals, plants, and insects. Each of these organisms employs multiple, interrelated, epigenetic mechanisms to maintain p
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10

Webster, K. E., M. K. O'Bryan, U. Aapola, et al. "255.Dnmt3L: a coordinator of epigenetic modifications during spermatogenesis." Reproduction, Fertility and Development 16, no. 9 (2004): 255. http://dx.doi.org/10.1071/srb04abs255.

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Spermatogenesis is a process with unique epigenetic requirements. The differentiation from diploid spermatogonia to haploid spermatozoa requires regulation of genomic imprint establishment, stage specific gene expression, meiotic division, and the histone-protamine transition. The methyltransferase regulator, Dnmt3L, is expressed during gametogenesis and is necessary for establishment of maternal methylation imprints in the oocyte. Targeted disruption of Dnmt3L does not appear to affect oogenesis, as mature oocytes are generated, however resultant heterozygous progeny die mid gestation due to
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11

Csaba, György. "Hormonal imprinting in the central nervous system: causes and consequences." Orvosi Hetilap 154, no. 4 (2013): 128–35. http://dx.doi.org/10.1556/oh.2013.29533.

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The notion of the perinatal „hormonal imprinting” has been published at first in 1980 and since that time it spred expansively. The imprintig develops at the first encounter between the developing receptor and the target hormone – possibly by the alteration of the methylation pattern of DNA – and it is transmitted to the progeny generations of the cell. This is needed for the complete development of the receptor’s binding capacity. However, molecules similar to the target hormone (hormone-analogues, drugs, chemicals, environmental pollutants) can also bind to the developing receptor, causing f
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12

Kono, Tomohiro. "Genetic modification for bimaternal embryo development." Reproduction, Fertility and Development 21, no. 1 (2009): 31. http://dx.doi.org/10.1071/rd08213.

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Full mammalian development typically requires genomes from both the oocyte and spermatozoon. Biparental reproduction is necessary because of parent-specific epigenetic modification of the genome during gametogenesis; that is, a maternal methylation imprint imposed during the oocyte growth period and a paternal methylation imprint imposed in pregonadal gonocytes. This leads to unequivalent expression of imprinted genes from the maternal and paternal alleles in embryos and individuals. It is possible to hypothesise that the maternal methylation imprint is necessary to prevent parthenogenesis, wh
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13

Smith, A. "Why is There No Diploid Overdose Effect in Prader-Willi Syndrome Due to Uniparental Disomy?" Acta geneticae medicae et gemellologiae: twin research 45, no. 1-2 (1996): 179–89. http://dx.doi.org/10.1017/s0001566000001288.

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AbstractDue to DNA technology, it is now apparent that the mechanisms of genetic disease are more complex than the model of a gene with biallelic expression in the diploid state. If a gene is imprinted, monoallelic expression is the norm when the chromosomes of a pair are inherited normally from each parent. Uniparental disomy (UPD) is the abnormal situation where both chromosomes of a pair come from the same parent. When the chromosome contains an imprinted gene, UPD may result in nullisomy or disomy for a functional copy of that gene. If there are two imprinted loci on the same chromosome, U
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14

Nicholls, R. D., M. T. C. Jong, C. C. Glenn, et al. "Multiple Imprinted Genes Associated with Prader-Willi Syndrome and Location of an Imprinting Control Element." Acta geneticae medicae et gemellologiae: twin research 45, no. 1-2 (1996): 87–89. http://dx.doi.org/10.1017/s000156600000115x.

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Our studies aim to identify the mechanisms and genes involved in genomic imprinting in mammalian development and human disease. Imprinting refers to an epigenetic modification of DNA that results in parent-of-origin specific expression during embryogenesis and in the adult. This imprint is reset at each generation, depending on the sex of the parental gametogenesis. Prader-Willi (PWS) and Angelman (AS) syndromes are excellent models for the study of genomic imprinting in humans, since these distinct neurobehavioural disorders are both associated with genetic abnormalities (large deletions, uni
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15

Sleutels, Frank, and Denise P. Barlow. "Investigation of Elements Sufficient To Imprint the Mouse Air Promoter." Molecular and Cellular Biology 21, no. 15 (2001): 5008–17. http://dx.doi.org/10.1128/mcb.21.15.5008-5017.2001.

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ABSTRACT Imprinted maternal-allele-specific expression of the mouse insulin-like growth-factor type 2 receptor (Igf2r) gene depends on a 3.7-kb element named region 2, located in the second intron of the gene. Region 2 carries a maternal-allele-specific methylation imprint and contains an imprinted CpG island promoter (Air) that expresses a noncoding antisense RNA from the paternal inherited allele only. Here, we use transgenes to test the minimal requirements for imprinting of Air and to test if the action of region 2 is restricted to Igf2r. Transgenes up to 9 kb with Air as a single promoter
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16

Menheniott, Trevelyan R., Kathryn Woodfine, Reiner Schulz, et al. "Genomic Imprinting of Dopa decarboxylase in Heart and Reciprocal Allelic Expression with Neighboring Grb10." Molecular and Cellular Biology 28, no. 1 (2007): 386–96. http://dx.doi.org/10.1128/mcb.00862-07.

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ABSTRACT By combining a tissue-specific microarray screen with mouse uniparental duplications, we have identified a novel imprinted gene, Dopa decarboxylase (Ddc), on chromosome 11. Ddc_exon1a is a 2-kb transcript variant that initiates from an alternative first exon in intron 1 of the canonical Ddc transcript and is paternally expressed in trabecular cardiomyocytes of the embryonic and neonatal heart. Ddc displays tight conserved linkage with the maternally expressed and methylated Grb10 gene, suggesting that these reciprocally imprinted genes may be coordinately regulated. In Dnmt3L mutant e
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17

Prawitt, Dirk, and Thomas Haaf. "Basics and disturbances of genomic imprinting." Medizinische Genetik 32, no. 4 (2020): 297–304. http://dx.doi.org/10.1515/medgen-2020-2042.

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Abstract Genomic imprinting ensures the parent-specific expression of either the maternal or the paternal allele, by different epigenetic processes (DNA methylation and histone modifications) that confer parent-specific marks (imprints) in the paternal and maternal germline, respectively. Most protein-coding imprinted genes are involved in embryonic growth, development, and behavior. They are usually organized in genomic domains that are regulated by differentially methylated regions (DMRs). Genomic imprints are erased in the primordial germ cells and then reset in a gene-specific manner accor
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18

Allen, Nick, and Wolf Reik. "What the papers say. Imprintor or imprinted?" BioEssays 14, no. 12 (1992): 857–59. http://dx.doi.org/10.1002/bies.950141211.

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19

Lee, Jiyoung, Kimiko Inoue, Ryuichi Ono, et al. "Erasing genomic imprinting memory in mouse clone embryos produced from day 11.5 primordial germ cells." Development 129, no. 8 (2002): 1807–17. http://dx.doi.org/10.1242/dev.129.8.1807.

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Genomic imprinting is an epigenetic mechanism that causes functional differences between paternal and maternal genomes, and plays an essential role in mammalian development. Stage-specific changes in the DNA methylation patterns of imprinted genes suggest that their imprints are erased some time during the primordial germ cell (PGC) stage, before their gametic patterns are re-established during gametogenesis according to the sex of individuals. To define the exact timing and pattern of the erasure process, we have analyzed parental-origin-specific expression of imprinted genes and DNA methylat
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20

Stephenson, Jessica F., and Michael Reynolds. "Imprinting can cause a maladaptive preference for infectious conspecifics." Biology Letters 12, no. 4 (2016): 20160020. http://dx.doi.org/10.1098/rsbl.2016.0020.

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Recognizing and associating with specific individuals, such as conspecifics or kin, brings many benefits. One mechanism underlying such recognition is imprinting: the long-term memory of cues encountered during development. Typically, juveniles imprint on cues of nearby individuals and may later associate with phenotypes matching their ‘recognition template’. However, phenotype matching could lead to maladaptive social decisions if, for instance, individuals imprint on the cues of conspecifics infected with directly transmitted diseases. To investigate the role of imprinting in the sensory eco
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21

Mikhak, Zamaneh, James P. Strassner, and Andrew D. Luster. "Lung dendritic cells imprint T cell lung homing and promote lung immunity through the chemokine receptor CCR4." Journal of Experimental Medicine 210, no. 9 (2013): 1855–69. http://dx.doi.org/10.1084/jem.20130091.

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T cell trafficking into the lung is critical for lung immunity, but the mechanisms that mediate T cell lung homing are not well understood. Here, we show that lung dendritic cells (DCs) imprint T cell lung homing, as lung DC–activated T cells traffic more efficiently into the lung in response to inhaled antigen and at homeostasis compared with T cells activated by DCs from other tissues. Consequently, lung DC–imprinted T cells protect against influenza more effectively than do gut and skin DC–imprinted T cells. Lung DCs imprint the expression of CCR4 on T cells, and CCR4 contributes to T cell
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22

Zhuang, Hai Yan, Hui Zhi Li, and Yang Xue. "Synthesis, Characterization and Selective Recognition of Lead Using a New Ion Imprinted Polymer Material." Advanced Materials Research 306-307 (August 2011): 688–91. http://dx.doi.org/10.4028/www.scientific.net/amr.306-307.688.

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A new ion-imprinted polymer (IIP) material was synthesized by copolymerization of 4-vinylpyridine(VP) as monomer, ethylene glycol dimethacrylate(EGDMA) as crosslinking agent and 2,2΄-azobisisobutyronitrile(AIBN) as initiator in the presence of Pb–1,5-diphenylcarbazone(Pb-DHCB) complex. Blank non-imprinted polymer (NIP) were prepared under identical conditions without the use of lead imprint ion. The synthesized polymers were characterized by IR spectroscopy and elemental analyzer techniques. Of the several polymers synthesized, only the imprinted polymer formed with binary complex of Pb2+–DHCB
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Yu, Chen-Chieh, Yi-Chuan Tseng, Pao-Yun Su, et al. "Incident angle–tuned, broadband, ultrahigh-sensitivity plasmonic antennas prepared from nanoparticles on imprinted mirrors." Nanoscale 7, no. 9 (2015): 3985–96. http://dx.doi.org/10.1039/c4nr05902f.

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We have used a direct imprint-in-metal method that is cheap and rapid to prepare incident angle-tuned, broadband, ultrahigh-sensitivity plasmonic antennas from nanoparticles (NPs) and imprinted metal mirrors.
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Mangia, Anita, Annalisa Chiriatti, Patrizia Chiarappa, et al. "Touch Imprint Cytology in Tumor Tissue Banks for the Confirmation of Neoplastic Cellularity and for DNA Extraction." Archives of Pathology & Laboratory Medicine 132, no. 6 (2008): 974–78. http://dx.doi.org/10.5858/2008-132-974-ticitt.

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Abstract Context.—Learning the characteristics of frozen tissue samples stored in tumor banks for biological studies remains a problem. Objective.—To assess the use of touch imprint cytology on fresh tissue samples as a rapid and reliable method of determining the presence and quantity of neoplastic cells before freezing. Design.—Touch imprint cytology was performed on 259 specimens of operable breast cancer. Touch imprints were prepared from fresh tissue specimens before freezing samples for storage. Each tumor sample was imprinted on a glass slide and stained with hematoxylin-eosin. Tumor ce
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Zheng, Xiaofeng, Sohayb Khaoulani, Nadia Ktari, et al. "Towards Clean and Safe Water: A Review on the Emerging Role of Imprinted Polymer-Based Electrochemical Sensors." Sensors 21, no. 13 (2021): 4300. http://dx.doi.org/10.3390/s21134300.

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This review critically summarizes the knowledge of imprinted polymer-based electrochemical sensors for the detection of pesticides, metal ions and waterborne pathogenic bacteria, focusing on the last five years. MIP-based electrochemical sensors exhibit low limits of detection (LOD), high selectivity, high sensitivity and low cost. We put the emphasis on the design of imprinted polymers and their composites and coatings by radical polymerization, oxidative polymerization of conjugated monomers or sol-gel chemistry. Whilst most imprinted polymers are used in conjunction with differential pulse
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Fan, X. Q., H. H. Zhang, S. Liu, K. Jia, and Z. Y. Gan. "Fabrication of Nanoscale Gratings by Nanoimprint on Silicon Wafer." Key Engineering Materials 315-316 (July 2006): 825–28. http://dx.doi.org/10.4028/www.scientific.net/kem.315-316.825.

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This paper presents an approach to fabricate nanoscale gratings by direct imprint on silicon substrate. Imprint conditions that affect the transcription accuracy, such as imprint temperature and pressure, are discussed, and the profile of the imprinted 80nm width gratings with a 250 nm pitch is checked by SEM. High fidelity and fine uniformity demonstrate that nanoimprint is an economical and efficient method to fabricate nanoscale gratings.
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Hata, Kenichiro, Masaki Okano, Hong Lei, and En Li. "Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice." Development 129, no. 8 (2002): 1983–93. http://dx.doi.org/10.1242/dev.129.8.1983.

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Genomic imprinting is regulated by differential methylation of the paternal and maternal genome. However, it remains unknown how parental imprinting is established during gametogenesis. In this study, we demonstrate that Dnmt3L, a protein sharing homology with DNA methyltransferases, Dnmt3a and Dnmt3b, but lacking enzymatic activity, is essential for the establishment of maternal methylation imprints and appropriate expression of maternally imprinted genes. We also show that Dnmt3L interacts with Dnmt3a and Dnmt3b and co-localizes with these enzymes in the nuclei of transfected cells, suggesti
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28

Liu, Qing Peng, Hui Zhi Li, Hai Yan Zhuang, and Mei Shan Pei. "Synthesis of a New Ion Imprinted Polymer Material for Separation and Preconcentration of Traces of Neodymium Ions." Advanced Materials Research 306-307 (August 2011): 705–8. http://dx.doi.org/10.4028/www.scientific.net/amr.306-307.705.

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Neodymium ion imprinted polymers (IIP) were synthesized by formation of ternary complexes of neodymium ion with Vanillin Benzidine(VLB) and 4-vinylpyridine (VP) as chelating agent following copolymerizing with styrene as func­tional monomer and ethylene glycol dimethacrylate (EGDMA) as cross-linking monomer using 2,2´-azobisisobutyronitrile as initiator. Control polymers(CPs) were prepared under identical conditions without the use of neodymium imprint ion. The synthesized polymers were characterized by IR spectroscopy and elemental analyzer techniques. Of the several polymers synthesized, onl
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Reik, Wolf, Fatima Santos, Kohzoh Mitsuya, Hugh Morgan, and Wendy Dean. "Epigenetic asymmetry in the mammalian zygote and early embryo: relationship to lineage commitment?" Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 358, no. 1436 (2003): 1403–9. http://dx.doi.org/10.1098/rstb.2003.1326.

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Epigenetic asymmetry between parental genomes and embryonic lineages exists at the earliest stages of mammalian development. The maternal genome in the zygote is highly methylated in both its DNA and its histones and most imprinted genes have maternal germline methylation imprints. The paternal genome is rapidly remodelled with protamine removal, addition of acetylated histones, and rapid demethylation of DNA before replication. A minority of imprinted genes have paternal germline methylation imprints. Methylation and chromatin reprogramming continues during cleavage divisions, but at the blas
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30

Rodrigues, Jessica A., Ping-Hung Hsieh, Deling Ruan, et al. "Divergence among rice cultivars reveals roles for transposition and epimutation in ongoing evolution of genomic imprinting." Proceedings of the National Academy of Sciences 118, no. 29 (2021): e2104445118. http://dx.doi.org/10.1073/pnas.2104445118.

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Parent-of-origin–dependent gene expression in mammals and flowering plants results from differing chromatin imprints (genomic imprinting) between maternally and paternally inherited alleles. Imprinted gene expression in the endosperm of seeds is associated with localized hypomethylation of maternally but not paternally inherited DNA, with certain small RNAs also displaying parent-of-origin–specific expression. To understand the evolution of imprinting mechanisms in Oryza sativa (rice), we analyzed imprinting divergence among four cultivars that span both japonica and indica subspecies: Nipponb
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Mackin, Sarah-Jayne, Avinash Thakur, and Colum P. Walsh. "Imprint stability and plasticity during development." Reproduction 156, no. 2 (2018): R43—R55. http://dx.doi.org/10.1530/rep-18-0051.

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There have been a number of recent insights in the area of genomic imprinting, the phenomenon whereby one of two autosomal alleles is selected for expression based on the parent of origin. This is due in part to a proliferation of new techniques for interrogating the genome that are leading researchers working on organisms other than mouse and human, where imprinting has been most studied, to become interested in looking for potential imprinting effects. Here, we recap what is known about the importance of imprints for growth and body size, as well as the main types of locus control. Interesti
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Xu, Zhi Gang, Zhi Min Liu, and Yun Li Chen. "Mixed-Template Molecularly Imprinted Technique and its Application Research." Advanced Materials Research 787 (September 2013): 99–105. http://dx.doi.org/10.4028/www.scientific.net/amr.787.99.

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Molecularly imprinted techniques have been rapidly developed in recent decade. Some novel molecularly imprinted techniques and some novel application forms of molecularly imprinted polymers have been developed. And it has been widely used in sample pretreatment. In this paper, novel mixed-template molecularly imprinted techniques are introduced. The development and applications of mixed-template molecularly imprinted techniques in recent decade are reviewed, including dual-template molecularly imprinted technique and multi-template molecularly imprinted technique, and its application in chroma
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Xu, Zhi Gang. "Molecularly Imprinted Polymers for the Analysis of Environmental Estrogen Bisphenol A." Advanced Materials Research 894 (February 2014): 143–48. http://dx.doi.org/10.4028/www.scientific.net/amr.894.143.

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Molecularly imprinted polymer (MIP) has the characteristics of predetermination, specific recognition and practicability. It can eliminate the interference of complicated matrix. It has been widely used as selective adsorption material in sample preparation. Bisphenol A is a common endocrine disruptor in environment. Its toxic effects and analysis have attracted widespread concern. In this paper, the molecularly imprinted sample preparation techniques for bisphenol A were comprehensively reported, including molecularly imprinted microspheres extraction, molecularly imprinted solid phase extrac
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Chakraborty, Soma, and Xyza Jane Templonuevo. "Removal of Triolein Lipid From Aqueous System by Molecularly Imprinted Chitosan and Its Derivative." KIMIKA 29, no. 1 (2018): 11–16. http://dx.doi.org/10.26534/kimika.v29i1.11-16.

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Chitosan was molecularly imprinted to remove triolein (a model lipid triacylglyceride) from water. Molecularly-imprinted chitosan (chitosan-MIP) was synthesized by crosslinking it with glutaraldehyde in the presence of triolein as the template at 50°C for 2h. MIPs of octanoyl derivative of chitosan(Oct-MIP) were also prepared by similar method. Octanoyl chitosan was synthesized by N-acylation of chitosan using octanoyl chloride at room temperature for 12h. Contact angle measurements of water droplet on chitosan and octanoyl chitosan revealed increased hydrophobicity of octanoyl derivative of c
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35

Horii, T., M. Kimura, S. Morita, Y. Nagao, and I. Hatada. "222 LOSS OF IMPRINTS OF PARTHENOGENETIC EMBRYONIC STEM CELLS IN MURINE CHIMERAS." Reproduction, Fertility and Development 19, no. 1 (2007): 228. http://dx.doi.org/10.1071/rdv19n1ab222.

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Mammalian parthenotes with the 2 maternal genomes cannot develop to term. By contrast, chimeras produced by parthenogenetic and normal embryos can develop to term. However, parthenogenetic cells contribute to restricted cells and body weights of the chimeras are reduced. These effects are due to aberrant expressions of imprinted genes, with complete methylation of the maternally methylated genes and complete loss of the paternally methylated genes. On the other hand, parthenogenetic ES (PGES) chimeras show more normal tissue contribution of donor cells and body weight compared to parthenogenet
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36

Anisimov, Sergey V. "A Prevalence of Imprinted Genes within the Total Transcriptomes of Human Tissues and Cells." Molecular Biology International 2012 (September 11, 2012): 1–29. http://dx.doi.org/10.1155/2012/793506.

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Genomic imprinting is an epigenetic phenomenon that causes a differential expression of paternally and maternally inherited alleles of a subset of genes (the so-called imprinted genes). Imprinted genes are distributed throughout the genome and it is predicted that about 1% of the human genes may be imprinted. It is recognized that the allelic expression of imprinted genes varies between tissues and developmental stages. The current study represents the first attempt to estimate a prevalence of imprinted genes within the total human transcriptome. In silico analysis of the normalized expression
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Monk, David, Philippe Arnaud, Jennifer M. Frost, et al. "Human imprinted retrogenes exhibit non-canonical imprint chromatin signatures and reside in non-imprinted host genes." Nucleic Acids Research 39, no. 11 (2011): 4577–86. http://dx.doi.org/10.1093/nar/gkq1230.

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Roth, Stephan Volkher, Ralph Döhrmann, Rainer Gehrke, et al. "Mapping the morphological changes of deposited gold nanoparticles across an imprinted groove." Journal of Applied Crystallography 48, no. 6 (2015): 1827–33. http://dx.doi.org/10.1107/s1600576715017987.

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The gradient gold layer morphology below the percolation threshold along a channel groove imprinted into a pressure-sensitive adhesive polymer film is studied. In order to elucidate the complex nanostructure of the sputter-deposited gold nanoparticle layer, nanobeam grazing-incidence small-angle X-ray scattering and imaging ellipsometry are used. Thus, the complex nanostructure of this metal–polymer nanocomposite can be detected, distinguished and identified. The presence of macroscopically curved structures, as introduced by the imprinted ridges, can cause deviations from the mean metal nanop
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Latif, Usman, Alexandra Seifner, and Franz L. Dickert. "Selective Detection of Erythrocytes with QCMs—ABO Blood Group Typing." Sensors 23, no. 17 (2023): 7533. http://dx.doi.org/10.3390/s23177533.

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Blood transfusion, as well as organ transplantation, is only possible after prior blood group (BG) typing and crossmatching. The most important blood group system is that of Landsteiner’s ABO classification based on antigen presence on the erythrocyte surfaces. A mass sensitive QCM (quartz crystal microbalance) sensor for BG typing has been developed by utilizing molecular imprinting technology. Polyvinylpyrrolidone (crosslinked with N,N-methylenebisacrylamide) is a favorable coating that was imprinted with erythrocytes of different blood groups. In total, 10 MHz quartz sheets with two resonat
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Lin, Chun Xiang, Ming Hua Liu, and Huai Yu Zhan. "Pb(II)-Imprinted Polymer Prepared by Graft Copolymerization of Acrylic Acid onto Cellulose." Advanced Materials Research 295-297 (July 2011): 2045–48. http://dx.doi.org/10.4028/www.scientific.net/amr.295-297.2045.

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The Pb( )-imprinted polymers were synthesized through homogeneous graft copolymerization of cellulose with acrylic acid in an homogeneous medium using Pb( ) as template. The prepared copolymers were characterized by FTIR and SEM. The batch adsorption experiments were conducted to evaluate the adsorption capacity of the Pb( )-imprinted beads. The results demonstrated that the imprinted beads showed significantly higher imprinting efficiency than those only consisting of poly(acrylic acid) without Pb( )-imprinted, and the selectively adsorption capacity of Pb( ) on imprinted beads was higher tha
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41

de Koning, Dirk-Jan, Henk Bovenhuis, and Johan A. M. van Arendonk. "On the Detection of Imprinted Quantitative Trait Loci in Experimental Crosses of Outbred Species." Genetics 161, no. 2 (2002): 931–38. http://dx.doi.org/10.1093/genetics/161.2.931.

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Abstract In this article, the quantitative genetic aspects of imprinted genes and statistical properties of methods to detect imprinted QTL are studied. Different models to detect imprinted QTL and to distinguish between imprinted and Mendelian QTL were compared in a simulation study. Mendelian and imprinted QTL were simulated in an F2 design and analyzed under Mendelian and imprinting models. Mode of expression was evaluated against the H0 of a Mendelian QTL as well as the H0 of an imprinted QTL. It was shown that imprinted QTL might remain undetected when analyzing the genome with Mendelian
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Renfree, Marilyn B., Eleanor I. Ager, Geoff Shaw, and Andrew J. Pask. "Genomic imprinting in marsupial placentation." REPRODUCTION 136, no. 5 (2008): 523–31. http://dx.doi.org/10.1530/rep-08-0264.

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Genomic imprinting is a widespread epigenetic phenomenon in eutherian mammals, which regulates many aspects of growth and development. Parental conflict over the degree of maternal nutrient transfer is the favoured hypothesis for the evolution of imprinting. Marsupials, like eutherian mammals, are viviparous but deliver an altricial young after a short gestation supported by a fully functional placenta, so can shed light on the evolution and time of acquisition of genomic imprinting. All orthologues of eutherian imprinted genes examined have a conserved expression in the marsupial placenta reg
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Murrell, Adele, and Santiago Uribe-Lewis. "Genomic imprinting and cancer: Remembering the parental origin." Biochemist 32, no. 5 (2010): 26–29. http://dx.doi.org/10.1042/bio03205026.

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Genomic imprinting results in only one copy of a diploid pair of alleles being expressed in a parentof-origin-specific manner. The ‘imprint’ encodes a memory of whether a gene came through the maternal or paternal line and contains the information that decides which parental copy will be active or silent. Imprints are established in the developing gametes, passed on to the next generation after fertilization where they are read and maintained in the somatic cells or erased and reset in the germ cells. The components of the ‘memory’ are a combination of epigenetic features such as DNA methylati
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Fahey, Marie E., Walter Mills, Desmond G. Higgins, and Tom Moore. "Maternally and Paternally Silenced Imprinted Genes Differ in Their Intron Content." Comparative and Functional Genomics 5, no. 8 (2004): 572–83. http://dx.doi.org/10.1002/cfg.437.

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Imprinted genes exhibit silencing of one of the parental alleles during embryonic development. In a previous study imprinted genes were found to have reduced intron content relative to a non-imprinted control set (Hurstet al., 1996). However, due to the small sample size, it was not possible to analyse the source of this effect. Here, we re-investigate this observation using larger datasets of imprinted and control (non-imprinted) genes that allow us to consider mouse and human, and maternally and paternally silenced, imprinted genes separately. We find that, in the human and mouse, there is r
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Mi, Zhi Yuan, Zhuo Ma, Xiao Li Li, Wei De Xiong, and Ying Qing Zhang. "Recognition of Papain by Konjac Glucomannan-Based Molecularly Imprinted Membrane." Advanced Materials Research 282-283 (July 2011): 687–90. http://dx.doi.org/10.4028/www.scientific.net/amr.282-283.687.

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Objective: To prepare a novel protein molecularly imprinted membrane. Methods: Konjac glucomanan was swollen, cross-linked, added papain and glycerol, dried to form imprinted membranes. Results: After eluted, the rebinding adsorption amounts of papain for imprinted and blank membranes were (12.692±3.452) μg/cm2 and (7.849±2.321) μg/cm2 respectively. The papain imprinted membrane had the highest imprinted factor α 1.8 for papain than for other proteins. Results of FT-IR and SEM showed that the cavity structure of the eluted membrane provided space for rebinding. Conclusions: Konjac glucomannan-
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Szabó, Piroska E., Gerd P. Pfeifer, and Jeffrey R. Mann. "Characterization of Novel Parent-Specific Epigenetic Modifications Upstream of the Imprinted Mouse H19Gene." Molecular and Cellular Biology 18, no. 11 (1998): 6767–76. http://dx.doi.org/10.1128/mcb.18.11.6767.

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ABSTRACT Genomic imprinting results in parent-specific monoallelic expression of a small number of genes in mammals. The identity of imprints is unknown, but much evidence points to a role for DNA methylation. The maternal alleles of the imprinted H19 gene are active and hypomethylated; the paternal alleles are inactive and hypermethylated. Roles for other epigenetic modifications are suggested by allele-specific differences in nuclease hypersensitivity at particular sites. To further analyze the possible epigenetic mechanisms determining monoallelic expression of H19, we have conducted in viv
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Mujahid, Adnan, Faisal Amin, Tajamal Hussain, Naseer Iqbal, Asma Tufail Shah, and Adeel Afzal. "Synthesis of Imprinted Polysiloxanes for Immobilization of Metal ions." MRS Proceedings 1675 (2014): 209–14. http://dx.doi.org/10.1557/opl.2014.867.

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ABSTRACTImprinting is a well-established technique to induce recognition features in both organic and inorganic materials for a variety of target analytes. In this study, ion imprinted polysiloxanes with varying percentage of coupling agent i.e. 3-chloro propyl trimethoxy silane (CPTM) were synthesized by sol-gel method for imprinting of Cr3+. The imprinting of Cr3+ in cross-linked siloxane network was investigated by FT-IR which indicates the metal ion is coordinated with oxygen atoms of polysiloxanes. SEM images revealed that imprinted polysiloxanes possess uniform particles of submicron siz
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Gabelica, Ivana, Floren Radovanović-Perić, Gordana Matijašić, Kristina Tolić Čop, Lidija Ćurković, and Dragana Mutavdžić Pavlović. "Synergistic Removal of Diclofenac via Adsorption and Photocatalysis Using a Molecularly Imprinted Core–Shell Photocatalyst." Materials 18, no. 10 (2025): 2300. https://doi.org/10.3390/ma18102300.

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In this work, a newly developed magnetic molecularly imprinted Fe3O4/SiO2/TiO2/MIP photocatalyst with diclofenac (DIC) as the template was prepared by microwave-assisted synthesis. The molecularly imprinted TiO2 layer has specific cavities designed for the DIC target molecule (imprint), resulting in a synergistic effect of extraction by adsorption and photocatalysis. For reference, non-imprinted magnetic nanoparticles (Fe3O4/SiO2/TiO2) were prepared using the same procedure. The obtained particles were characterized by X-ray diffraction analysis (XRD), Fourier transform infrared spectroscopy (
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Saferali, Aabida, Sanny Moussette, Donovan Chan, et al. "DNA methyltransferase 1 (Dnmt1) mutation affects Snrpn imprinting in the mouse male germ line." Genome 55, no. 09 (2012): 673–82. http://dx.doi.org/10.1139/g2012-056.

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DNA methylation and DNA methyltransferases are essential for spermatogenesis. Mutations in the DNA methyltransferase Dnmt1 gene exert a paternal effect on epigenetic states and phenotypes of offspring, suggesting that DNMT1 is important for the epigenetic remodeling of the genome that takes place during spermatogenesis. However, the specific role of DNMT1 in spermatogenesis and the establishment of genomic imprints in the male germ line remains elusive. To further characterize the effect of DNMT1 deficiency on the resetting of methylation imprints during spermatogenesis, we analyzed the methyl
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Lu, Ziyang, Zehui Yu, Jinbo Dong, et al. "Enhanced Photocatalytic Activity and Selectivity of a Novel Magnetic PW@PEDOT Imprinted Photocatalyst with Good Reproducibility." Nano 13, no. 02 (2018): 1850020. http://dx.doi.org/10.1142/s1793292018500200.

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The novel magnetic PW-doped PEDOT (PW@PEDOT) imprinted photocatalyst with good reproducibility was prepared by the surface imprinting technique and microwave heating method. Due to the existence of PW@PEDOT and imprinted cavity in the imprinted layer, the as-prepared magnetic PW@PEDOT imprinted photocatalyst not only had higher photocatalytic activity, but also had the excellent specific recognition ability for selective photodegradation of TC. This paper proposed a new idea to prepare the imprinted photocatalysts.
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