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1

Kim, Kyungmin, Daseul Kim, Hyunjin Lee, Tae Hoon Lee, Ki-Young Kim, and Hakwon Kim. "New Pyrimidinone-Fused 1,4-Naphthoquinone Derivatives Inhibit the Growth of Drug Resistant Oral Bacteria." Biomedicines 8, no. 6 (June 15, 2020): 160. http://dx.doi.org/10.3390/biomedicines8060160.

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Background: Dental caries is considered to be a preventable disease, and various antimicrobial agents have been developed for the prevention of dental disease. However, many bacteria show resistance to existing agents. Methods/Principal Findings: In this study, four known 1,4-naphthoquinones and newly synthesized 10 pyrimidinone-fused 1,4-naphthoquinones, i.e. KHQ 701, 702, 711, 712, 713, 714, 715, 716, 717 and 718, were evaluated for antimicrobial activity against Enterococcus faecalis, Enterococcus faecium, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus mutans, Streptococcus sobrinus, Porphyromonas gingivalis, Actinomyces viscosus and Fusobacterium nucleatum. Pyrimidinone-fused 1,4-naphthoquinones were synthesized in good yields through a series of chemical reactions from a commercially available 1,4-dihydroxynaphthoic acid. MIC values of KHQ 711, 712, 713, 714, 715, 716, 717 and 718 were 6.25–50 μg/mL against E. faecalis (CCARM 5511), 6.25–25 μg/mL against E. faecium (KACC11954) and S. aureus (CCARM 3506), 1.56–25 μg/mL against S. epidermidis (KACC 13234), 3.125–100 μg/mL against S. mutans (KACC16833), 1.56–100 μg/mL against S. sobrinus (KCTC5809) and P. gingivalis (KCTC 5352), 3.125–50 μg/mL against A. viscosus (KCTC 9146) and 3.125–12.5 μg/mL against F. nucleatum (KCTC 2640) with a broth microdilution assay. A disk diffusion assay with KHQ derivatives also exhibited strong susceptibility with inhibition zones of 0.96 to 1.2 cm in size against P. gingivalis. Among the 10 compounds evaluated, KHQ 711, 712, 713, 715, 716 and 717 demonstrated strong antimicrobial activities against the 9 types of pathogenic oral bacteria. A pyrimidin-4-one moiety comprising a phenyl group at the C2 position and a benzyl group at the N3 position appears to be essential for physiological activity. Conclusion/Significance: Pyrimidinone-fused 1,4-naphthoquinones synthesized from simple starting compounds and four known 1,4-naphthoquinones were synthesized and showed strong antibacterial activity to the 9 common oral bacteria. These results suggest that these derivatives should be prospective for the treatment of dental diseases caused by oral bacteria, including drug-resistant strains.
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2

Meyer, Ulrich. "Zur Einordnung von J. S. Bachs einzeln überlieferten Orgelchorälen." Bach-Jahrbuch 60 (March 15, 2018): 75–89. http://dx.doi.org/10.13141/bjb.v19741983.

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Dieser Artikel beschäftigt sich mit den von Klotz im Band IV/3 der NBA veröffentlichten Werken. Vermutlich vor den Siebzehn Chorälen entstanden etwa zwischen 1703 und 1709 folgende Werke: BWV 741, 700 und 735 unter dem Einfluss von Böhm; BWV 737, 724 und O Lamm Gottes, unschuldig unter dem Einfluss von Pachelbel; BWV 721, 718 und 720 unter dem Einfluss von Buxtehude. Vermutlich zur gleichen Zeit wie die Siebzehn Choräle und später wurden die folgenden Werke um 1709 bis 1717 komponiert: Choralbegleitungen und Lehrwerke BWV 715, 726, 722, 729, 732, 738, 725, 730, 706 und die Choralsätze in BWV 690, 695, 713, 734 und 736; Stücke unter dem Einfluss von Pachelbel BWV 712, 696-699, 701, 703, 704, 733, 736 (motivische Behandlung des Chorals), 694, 710, 717, 713, 695 (thematische Behandlung des Chorals), 711, 734 (regelmäßige Behandlung des Chorals); Choräle im Stil des Orgelbüchlein BWV 731,724,709 (koloristisch), 714 (kanonisch), 690 (zwischen Partita und Orgelbüchlein). In den Jahren 1720 bzw. 1722 nahm Bach BWV 691 und 728 in die Klavierbüchlein-Kopien auf. Der Autor hält O Lamm Gottes, unschuldig für authentisch, den hinzugefügten Choral jedoch für falsch zugeschrieben. - "Fantasia" kennzeichnet Orgelchoräle verschiedener Art in der Weimarer Zeit, großformatige Arrangements mit Cantus firmus im Bass solche der Leipziger Zeit. (Übertragung des englischen Resümees am Ende des Bandes) Erwähnte Artikel: Fritz Dietrich: J. S. Bachs Orgelchoral und seine geschichtlichen Wurzeln. BJ 1929, S. 1-89 Ulrich Meyer: Zur Frage der inneren Einheit von Bachs Siebzehn Chorälen (BWV 651-667). BJ 1972, S. 61-75
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3

&NA;. "718." Neurosurgery 53, no. 2 (August 2003): 476. http://dx.doi.org/10.1097/00006123-200308000-00052.

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4

Hooten, W., J. Schmidt, J. Kerkvliet, C. Townsend, J. Hodgson, and B. Bruce. "(718)." Journal of Pain 8, no. 4 (April 2007): S30. http://dx.doi.org/10.1016/j.jpain.2007.02.122.

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5

Van Cleave, Alisa, Megan Roosen-Runge, Alison Miller, Katrina Karkazis, and David Magnus. "718." Critical Care Medicine 41 (December 2013): A177. http://dx.doi.org/10.1097/01.ccm.0000439956.11645.09.

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6

Pirrone, Massimiliano, Riccardo Pinciroli, Cristina Mietto, David Imber, Christopher Chenelle, Robert Kacmarek, and Lorenzo Berra. "718." Critical Care Medicine 42 (December 2014): A1533. http://dx.doi.org/10.1097/01.ccm.0000458215.50950.51.

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7

Saha, Biplab, Barry Kreiswirth, and Kristin Fless. "718." Critical Care Medicine 43 (December 2015): 181. http://dx.doi.org/10.1097/01.ccm.0000474546.96312.38.

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8

Matta, Simran Kaur, Purvesh Patel, and Kalpalatha Guntupalli. "718." Critical Care Medicine 47 (January 2019): 339. http://dx.doi.org/10.1097/01.ccm.0000551469.96442.ff.

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9

Fleenor, Bradley. "718." Medicine & Science in Sports & Exercise 51, Supplement (June 2019): 173. http://dx.doi.org/10.1249/01.mss.0000561024.95150.8e.

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10

Barbash, Ian, Sheheryar Kabraji, Maria Han, Rachel Kohn, and Ryan Thompson. "718." Critical Care Medicine 40 (December 2012): 1–328. http://dx.doi.org/10.1097/01.ccm.0000424933.01312.56.

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11

Priano, James, Jason Vilar, Darla Quevedo, and Kaitlin Rzasa. "718." Critical Care Medicine 48 (January 2020): 339. http://dx.doi.org/10.1097/01.ccm.0000626612.57278.2b.

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12

Lenzinger, E., K. Diamant, E. Vytiska-Binstorfer, and S. Kasper. "Prämenstruelle dysphorische Störung (PMDS). (Nervenarzt 68:708–718)." Der Gynäkologe 31, no. 1 (January 28, 1998): 100–101. http://dx.doi.org/10.1007/pl00003079.

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13

Labus, J., E. Mayer, S. Berman, L. Chang, J. Fallon, and B. Naliboff. "(306/718)." Journal of Pain 7, no. 4 (April 2006): S1. http://dx.doi.org/10.1016/j.jpain.2006.01.408.

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14

Subramanian, G., J. Andrews, and J. Brierley. "ABSTRACT 718." Pediatric Critical Care Medicine 15 (May 2014): 162. http://dx.doi.org/10.1097/01.pcc.0000449444.14804.e0.

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15

Berrios, R., R. N. Clarke, R. Gosden, H. Bang, N. Zaninovic, and L. Veeck Gosden. "P-718." Fertility and Sterility 86, no. 3 (September 2006): S399—S400. http://dx.doi.org/10.1016/j.fertnstert.2006.07.1103.

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16

 . "718 Zorgboulevards." Zorg en Financiering 4, no. 4 (April 2005): 173. http://dx.doi.org/10.1007/bf03090836.

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17

Duncan, Graham. "718. MORAEA ARISTATA." Curtis's Botanical Magazine 28, no. 4 (December 2011): 287–96. http://dx.doi.org/10.1111/j.1467-8748.2011.01756.x.

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18

Sakib, Md Annaz Mus, Mohammad Ashik Imran Khan, Muhammad Ashif Mashud Chowdhury, Md Moniruzzaman, and Md Saiful Islam. "Sudden Cardiac Death (SCD) -A Raising Concern of Modern Cardiology." KYAMC Journal 7, no. 1 (August 29, 2017): 714–18. http://dx.doi.org/10.3329/kyamcj.v7i1.33765.

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19

Radavich, John F. "Metallography of Alloy 718." JOM 40, no. 7 (July 1988): 42–43. http://dx.doi.org/10.1007/bf03258150.

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20

A., C. "Tiempo de cumbres." ECA: Estudios Centroamericanos 46, no. 513-514 (August 31, 1991): 711–18. http://dx.doi.org/10.51378/eca.v46i513-514.6033.

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21

Dressler, M., M. Nofz, R. Saliwan-Neumann, I. Dörfel, and M. Griepentrog. "Sol–gel derived alumina layers on nickel-base superalloy Inconel-718 (IN-718)." Thin Solid Films 517, no. 2 (November 2008): 786–92. http://dx.doi.org/10.1016/j.tsf.2008.08.124.

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22

Doleker, Kadir Mert, Okan Odabas, Yasin Ozgurluk, Hangardas Askerov, and Abdullah Cahit Karaoglanli. "Effect of high temperature oxidation on Inconel 718 and Inconel 718/YSZ/Gd2Zr2O7." Materials Research Express 6, no. 8 (June 12, 2019): 086456. http://dx.doi.org/10.1088/2053-1591/ab26d8.

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23

Xue, Han, Wu Lijun, Xia Hui, Liu Runguang, Wang Shaogang, and Chen Zhonglin. "Superplastic properties of Inconel 718." Journal of Materials Processing Technology 137, no. 1-3 (June 2003): 17–20. http://dx.doi.org/10.1016/s0924-0136(02)01055-5.

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24

Rahman, M., W. K. H. Seah, and T. T. Teo. "The machinability of inconel 718." Journal of Materials Processing Technology 63, no. 1-3 (January 1997): 199–204. http://dx.doi.org/10.1016/s0924-0136(96)02624-6.

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25

Miller, M. K., S. S. Babu, and M. G. Burke. "Intragranular precipitation in alloy 718." Materials Science and Engineering: A 270, no. 1 (September 1999): 14–18. http://dx.doi.org/10.1016/s0921-5093(99)00235-x.

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26

He, J., S. Fukuyama, and K. Yokogawa. "Deformation bands in Inconel 718." Materials Science and Technology 11, no. 9 (September 1995): 914–20. http://dx.doi.org/10.1179/mst.1995.11.9.914.

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27

Wang, Z. Y., K. P. Rajurkar, J. Fan, S. Lei, Y. C. Shin, and G. Petrescu. "Hybrid machining of Inconel 718." International Journal of Machine Tools and Manufacture 43, no. 13 (October 2003): 1391–96. http://dx.doi.org/10.1016/s0890-6955(03)00134-2.

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28

Sundararaman,, M., and P. Mukhopadhyay,. "Carbide Precipitation in Inconel 718." High Temperature Materials and Processes 11, no. 1-4 (January 1993): 351–68. http://dx.doi.org/10.1515/htmp.1993.11.1-4.351.

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29

Xavior, M. Anthony, Mahesh Patil, Abheek Maiti, Mrinal Raj, and Nitesh Lohia. "Machinability studies on INCONEL 718." IOP Conference Series: Materials Science and Engineering 149 (September 2016): 012019. http://dx.doi.org/10.1088/1757-899x/149/1/012019.

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30

 . "718 Mandometerbehandeling Geen Awbz-Zorg." Zorg en Financiering 7, no. 6 (June 2008): 36. http://dx.doi.org/10.1007/bf03096954.

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31

Knorovsky, G. A., M. J. Cieslak, T. J. Headley, A. D. Romig, and W. F. Hammetter. "INCONEL 718: A solidification diagram." Metallurgical Transactions A 20, no. 10 (October 1989): 2149–58. http://dx.doi.org/10.1007/bf02650300.

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32

deBarbadillo, John J., and Sarwan K. Mannan. "Alloy 718 for Oilfield Applications." JOM 64, no. 2 (February 2012): 265–70. http://dx.doi.org/10.1007/s11837-012-0238-z.

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33

Wolf, T., I. Iovkov, and D. Biermann. "DISCONTINUOUS DRILLING OF INCONEL 718." MM Science Journal 2021, no. 3 (June 30, 2021): 4569–75. http://dx.doi.org/10.17973/mmsj.2021_7_2021061.

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Inconel 718 as one of the most common nickel-base alloys is mainly characterized by its high-temperature strength. Thus, in particular drilling is subject to high tool wear due to high thermomechanical loads on the cutting edges. To reduce those effects an alternative process design of discontinuous drilling was developed which contains a periodical interruption of the machining process with the aim of a targeted wetting and cooling of the tool at regular intervals. Thus, a significant reduction of the thermal load on the tool should provide a benefit to the drilling process and extend the tool life. Numerical and experimental investigations were used to analyze the introduced process strategy modification.
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34

Momeni, Amir, Seyed Mehdi Abbasi, Maryam Morakabati, and Hasan Badri. "A Comparative Study on the Hot Working Behavior of Inconel 718 and ALLVAC 718 Plus." Metallurgical and Materials Transactions A 48, no. 3 (January 3, 2017): 1216–29. http://dx.doi.org/10.1007/s11661-016-3904-x.

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35

Sanviemvongsak, Tom, Daniel Monceau, Martin Madelain, Clara Desgranges, James Smialek, and Bruno Macquaire. "Cyclic oxidation of alloy 718 produced by additive manufacturing compared to a wrought-718 alloy." Corrosion Science 192 (November 2021): 109804. http://dx.doi.org/10.1016/j.corsci.2021.109804.

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36

Ren, Jia Long, Qing Yu Zheng, Ren He, and Chun Yan Zhang. "The Cutting Simulation of Inconel 718." Applied Mechanics and Materials 43 (December 2010): 717–21. http://dx.doi.org/10.4028/www.scientific.net/amm.43.717.

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The chemical composition and properties of nickel-based superalloy Inconel 718 was investigated first. Turning Inconel 718 was simulated by Deform-3D software to figure out main affection factors, and optimal combination of cutting speed, feed rate and cutting depth was introduced. In addition, different cooling and Lubrication methods (heat transfer coefficient f of cooling and tool-chip friction factors) for cutting of Inconel 718 was studied, and a best cooling/lub mode was obtained.
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37

Zhao, Heng, Qing Bin Liu, Gang Lee, and Da Wei Yao. "The Addition of Zr in Nickel-Based Inconel 718 Superalloy to Prevent Hot Cracks Propagation." Key Engineering Materials 727 (January 2017): 3–8. http://dx.doi.org/10.4028/www.scientific.net/kem.727.3.

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The Inconel 718 alloy owes high strength and ductility at high temperature due to precipitation strengthening. In order to upgrade productility of Inconel 718 alloy, the Inconel 718 alloy solve hot crackings through Zr additions. The result shows that, the Inconel 718 alloy with Zr addition achieves grain size refinement and homogenization effect. It is suggested that, homogenization process, such as temperature point and time control, realizes low content of Nb segregation which is the key to prevent hot crackings. At the same time, through dendrite space measurement, the grain refinement realize high productivity of forged Inconel 718 alloy, as a another method of soft effect. In conclusion, adding Zr element is one of dominant methods for producing high quality of Inconel 718 alloy.
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38

Hossain, Mohammad Ashraf, Shigefumi Maesaki, Hiroshi Kakeya, Tetsuhiro Noda, Katsunori Yanagihara, Eisuke Sasaki, Yoichi Hirakata, Kazunori Tomono, Takayoshi Tashiro, and Shigeru Kohno. "Efficacy of NS-718, a Novel Lipid Nanosphere-Encapsulated Amphotericin B, againstCryptococcus neoformans." Antimicrobial Agents and Chemotherapy 42, no. 7 (July 1, 1998): 1722–25. http://dx.doi.org/10.1128/aac.42.7.1722.

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ABSTRACT In vitro and in vivo efficacies of NS-718, a lipid nanosphere-encapsulated amphotericin B (AMPH-B), have been studied. Of the tested AMPH-B formulations, NS-718 had the lowest MIC forCryptococcus neoformans. In a murine model, low-dose therapy (0.8 mg/kg of body weight) with NS-718 showed higher efficacy than that with AmBisome. High-dose therapy (2.0 mg/kg) with NS-718 was much more effective than those with Fungizone and AmBisome. In mice treated with a high dose of NS-718, only a few yeast cells had grown in lung by 7 days after inoculation. A pharmacokinetic study showed higher concentrations of AMPH-B in lung following administration of NS-718 than after administration of AmBisome. Our results indicated that NS-718, a new AMPH-B formulation, is a promising antifungal agent for treatment of pulmonary cryptococcosis and could be the most effective antifungal agent against C. neoformans infections.
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39

Ehrlin, Niklas, Christina Bjerkén, and Martin Fisk. "Cathodic hydrogen charging of Inconel 718." AIMS Materials Science 3, no. 4 (2016): 1350–64. http://dx.doi.org/10.3934/matersci.2016.4.1350.

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40

Martinolli, Karina, Tarcila Sugahara, Danieli A. P. Reis, Carlos de Moura Neto, Ana Cláudia Hirschmann, and Antônio Augusto Couto. "Evaluation of Inconel 718 Creep Behavior." Defect and Diffusion Forum 326-328 (April 2012): 525–29. http://dx.doi.org/10.4028/www.scientific.net/ddf.326-328.525.

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Superalloys are used primarily in aerospace applications. These applications require a material with high mechanical strength, good resistance to fatigue and creep, good corrosion resistance and ability to operate continuously at elevated temperatures. These alloys were developed for elevated temperature service, where relatively severe mechanical stressing is encountered, and where high surface stability is frequently required. Inconel 718 has being investigated because it is one of the most widely used superalloys. Constant load creep tests were conducted on a standard creep machine at 600 and 700°C and stress levels of 300 MPa. Sets of curves and experimental parameters for the primary, secondary and tertiary regions, as a function of stress and temperature applied were obtained. The ductility, the creep rate and lifetime was evaluated.
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41

Fournier, L., D. Delafosse, and T. Magnin. "Cathodic hydrogen embrittlement in alloy 718." Materials Science and Engineering: A 269, no. 1-2 (August 1999): 111–19. http://dx.doi.org/10.1016/s0921-5093(99)00167-7.

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42

Tellkamp, V. L., M. L. Lau, A. Fabel, and E. J. Lavernia. "Thermal spraying of nanocrystalline inconel 718." Nanostructured Materials 9, no. 1-8 (January 1997): 489–92. http://dx.doi.org/10.1016/s0965-9773(97)00107-4.

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43

Keller, Benjamin P., Shawn E. Nelson, Kyle L. Walton, Tushar K. Ghosh, Robert V. Tompson, and Sudarshan K. Loyalka. "Total hemispherical emissivity of Inconel 718." Nuclear Engineering and Design 287 (June 2015): 11–18. http://dx.doi.org/10.1016/j.nucengdes.2015.02.018.

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44

Patel, Vivek, Akash Sali, James Hyder, Mike Corliss, David Hyder, and Wayne Hung. "Electron Beam Welding of Inconel 718." Procedia Manufacturing 48 (2020): 428–35. http://dx.doi.org/10.1016/j.promfg.2020.05.065.

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45

Azadian, Saied, Liu-Ying Wei, and Richard Warren. "Delta phase precipitation in Inconel 718." Materials Characterization 53, no. 1 (September 2004): 7–16. http://dx.doi.org/10.1016/j.matchar.2004.07.004.

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46

Hickey, A., C. Battersby, P. Charlesworth, M. O. Meara, J. Hind, and K. Tavener. "718 Infant Feeding Following Gastroschisis Repair." Archives of Disease in Childhood 97, Suppl 2 (October 1, 2012): A207. http://dx.doi.org/10.1136/archdischild-2012-302724.0718.

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47

Mills, W. J., and L. D. Blackburn. "Fracture Toughness Variations in Alloy 718." Journal of Engineering Materials and Technology 110, no. 3 (July 1, 1988): 286–93. http://dx.doi.org/10.1115/1.3226050.

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Heat-to-heat and product-form variations in the JIc fracture toughness of Alloy 718 were examined at 24°C, 427°C, and 538°C using the multiple-specimen JR-curve method. Five different material heats along with three product forms from one of the heats were tested in the conventional heat-treatment condition. Statistical analysis revealed only two significantly different JIc levels of 48 kJ/m2 and 74 kJ/m2 for these materials. These two mean JIc levels were independent of temperature. A minimum-expected JIc level based on a tolerance interval bracketing 90 percent of the lower JIc population at a 95 percent confidence level was evaluated as 33 kJ/m2. Coarse δ precipitates controlled the fracture properties by initiating secondary dimples that pre-empted continued growth of primary dimples nucleated by broken carbide inclusions.
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48

Choudhury, I. A., and M. A. El-Baradie. "Machining nickel base superalloys: Inconel 718." Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture 212, no. 3 (March 1, 1998): 195–206. http://dx.doi.org/10.1243/0954405981515617.

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A series of machining experiments of Inconel 718 has been carried out using coated and uncoated carbides. The paper describes the effects of cutting variables (speed, feed and depth of cut) on cutting forces and tool life. Carbide tools in the form of 80° rhomboid shaped inserts without any chip breaker have been used at different cutting conditions. The machining parameters have been optimized by measuring cutting forces. Flank wear was considered as the criterion for tool life. A comparison between the uncoated and coated tools has been made using the Taylor's tool life exponents of speed, feed and depth of cut. The tool life of coated tools was not found to be better than that of the uncoated tools.
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49

Szablewski, Piotr, Tomasz Dobrowolski, and Tadeusz Chwalczuk. "Optimization of Inconel 718 milling strategies." Mechanik 92, no. 12 (December 9, 2019): 824–26. http://dx.doi.org/10.17814/mechanik.2019.12.112.

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This paper applies to the tests of the machining of a part made of supper alloy – nickel alloy – Inconel 718, using a monolithic carbide cutter. The paper includes a different versions of cutting methods with variable cutting parameters and machining strategies. The used sustainable machining process allowed to obtain control over the tool wear.
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50

Agazhanov, A. Sh, D. A. Samoshkin, and Yu M. Kozlovskii. "Thermophysical properties of Inconel 718 alloy." Journal of Physics: Conference Series 1382 (November 2019): 012175. http://dx.doi.org/10.1088/1742-6596/1382/1/012175.

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