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Journal articles on the topic 'In-hospital lethal outcome'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Ekkert, Aleksandra, Une Jokimaitytė, Valerija Tutukova, Givi Lengvenis, Rytis Masiliūnas, and Dalius Jatužis. "Endovascular Treatment of Basilar Artery Occlusion: What Can We Learn from the Results?" Medicina 59, no. 1 (2022): 96. http://dx.doi.org/10.3390/medicina59010096.

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Background and Objectives: Current guidelines lack specific endovascular treatment (EVT) recommendations for posterior circulation stroke (PCS). The results of earlier studies are controversial. We aimed to compare early hospital outcomes of stroke caused by large-vessel occlusion (LVO) treated with EVT or bridging therapy (BT) in anterior circulation stroke (ACS) versus PCS (middle cerebral artery occlusion (MCAO) and basilar artery occlusion (BAO), and establish the risk factors for poor outcome. Materials and Methods: we analyzed the data of 279 subjects treated with EVT due to LVO-caused s

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Konjo, Hadžan, Emira Švraka, Đemil Omervić, and Dijana Avdić. "Incidence of hospital mortality in polytrauma patients in a tertiary center in Bosnia and Herzegovina." Journal of Health Sciences 6, no. 1 (2016): 67–71. http://dx.doi.org/10.17532/jhsci.2016.331.

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Introduction: In the late 70s of the last century, the mortality rate due to polytrauma amounted to 40%. This led to a new approach to this patient category with the goal of improving the treatment outcome. According to the German trauma register, the rate of mortality in polytrauma at the end of the last century was 18.6%. The goal of this study is to determine the incidence of hospital mortality in polytrauma patients in a tertiary institution in Bosnia and Herzegovina.Methods: We analyzed patient medical records from the Intensive Care Unit of the Clinic of Orthopedics and Traumatology at U

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Sokolov, V. A., E. I. Bialik, I. A. Sharipov, et al. "Outcome prognosis in combined trauma of loco-motor system and brain injury at early hospital period." N.N. Priorov Journal of Traumatology and Orthopedics 4, no. 2 (1997): 7–12. http://dx.doi.org/10.17816/vto106691.

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Retrospective study of complications and lethality in 284 victims with combined brain and loco-motor system injury allowed to determine the most important complications that were the cause of lethal outcomes in a great number of cases. Those complications were edema and cerebrum dislocation, acute bleed, early and delayed pneumonia. Purulence of soft tissue wounds and open fractures significance influenced the duration and outcome of treatment. Criteria and schemes of outcome prognosis as well as development of soft tissue wounds and open fractures purulence were worked out.

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Chereshnev, V. A., T. V. Gavrilova, M. V. Chereshneva, A. P. Sergienko, and N. N. Vorob’eva. "Ophthalmopathology in HIV patients with a lethal outcome." HIV Infection and Immunosuppressive Disorders 12, no. 2 (2020): 97–103. http://dx.doi.org/10.22328/2077-9828-2020-12-2-97-103.

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Aim. The analysis of ophthalmopathology in HIV patients with a lethal outcome. Materials and methods. 371 HIV patients with lethal outcome were treated in Perm Regional Clinical Infectious Diseases Hospital within 13 years; 143 (38,5%) were examined by an ophthalmologist; ophthalmopathology was identified in 44,1% of individuals. The medical histories of these patients have been analyzed retrospectively, the remaining patients are excluded from the studies due to no changes of the organ of vision. Examination of patients included conventional eye care methods, immunological (determination of C

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Bobelytė, Odeta, Ieva Gailiūtė, Vytautas Zubka, and Virginija Žilinskaitė. "Sepsis epidemiology and outcome in the paediatric intensive care unit of Vilnius University Children’s Hospital." Acta medica Lituanica 24, no. 2 (2017): 113–20. http://dx.doi.org/10.6001/actamedica.v24i2.3492.

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Research was carried out at the paediatric intensive care unit (paediatric ICU) of the Children’s Hospital, affiliate of Vilnius University Hospital Santariškių klinikos. Background. Being the most common cause of children’s death, sepsis is a challenge for most physicians. In order to improve the outcomes, it is important to know the aetiology and peculiarities of sepsis in a particular region and hospital. The aim of this study was to analyse the outcomes of sepsis in a paediatric intensive care unit and their relation with patients’ characteristics and causative microorganisms. Materials an

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Shumynskyi, I., M. Sabadosh, V. Gurianov, and A. Kopchak. "Predicting lethal outcome risks in patients with craniomaxillofacial trauma and polytrauma by the ISS and NISS." General Surgery, no. 2 (December 30, 2022): 13–19. http://dx.doi.org/10.30978/gs-2022-2-13.

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Multiple papers reveal no reliable difference between early and delayed maxillofacial injuries treatment in postoperative complications in patients with craniomaxillofacial trauma and polytrauma. A choice factor of the treatment tactics is the lethal outcome risk, as well as the lethal outcome prognosis. In order to objectivize the severity of trauma authors suggested the assessment scores which represent patient’s condition severity in points and provide lethal outcome risk estimation, — Injury Severity Score (ISS) and New Injury Severity Score (NISS), each with advantages and disadvantages o

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Zeltyn-Abramov, E. M., M. A. Lysenko, N. F. Frolova, et al. "Risk factors of adverse outcome of COVID-19 and experience of Tocilizumab administration in patients on maintenance hemodialysis due to diabetic kidney disease." Diabetes mellitus 24, no. 1 (2021): 17–31. http://dx.doi.org/10.14341/dm12688.

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BACKGROUND: Patients with Type 2 Diabetes (T2DM) and patients on maintenance hemodialysis (MHD) are at a high risk of adverse clinical course of COVID-19. To date, the causes of high mortality in these groups are not fully understood. Data about peculiarity of clinical course and Tocilizumab (TCZ) administration in patients with T2DM receiving MHD due to outcome of diabetic kidney disease (DKD) are not yet highlighted in current publications.AIMS: Identification of risk factors (RF) of adverse COVID-19 outcome and evaluation of TCZ administration in patients with T2DM receiving MHD due to DKD.

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Pandilov, Stefan, Suzana Klenkoski, Elena Jovanovska Janeva, et al. "C-reactive protein and Neutrophil-Lymphocyte Ratio as predictors of clinical severity of COVID-19." Archives of Public Health 13, no. 2 (2021): 130–43. http://dx.doi.org/10.3889/aph.2021.6006.

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COVID-19 is an infectious disease that can manifest quite differently. In this study we examined the relationship between the value of serum CRP(C-reactive protein) andneutrophil-lymphocyte ratio (NLR) as predictor factors for the development of a severe clinical manifestation in COVID19 patients. Materials and methods: We followed 95 COVID-19 positive patients who were hospitalized at the University Clinic for Eye Diseases - COVID Center. We analyzed the initial laboratory parameters of white blood cells and CRP on admission of the patients and the results of laboratory analyses performed bef

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Zyryanov, S. K., O. I. Butranova, and A. A. Abramova. "Characteristics of hospitalized patients with lethal outcome due to COVID-19." Clinical Microbiology and Antimicrobial Chemotherapy 25, no. 4 (2023): 350–57. http://dx.doi.org/10.36488/cmac.2023.4.350-357.

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Objective. To analyze the characteristics of patients with severe COVID-19 and lethal outcome. Materials and Methods. This retrospective pharmacoepidemiological study (March – April 2021) enrolled 172 patients with confirmed COVID-19 and death in the intensive care unit of City Clinical Hospital No. 24. Results. The mean age was 74.4 ± 7.4 years, patients over 65 years old – 81% (n = 139), over 75 years old – 44% (n = 75). Males – 66% (n = 113). All patients had a secondary bacterial infection. The predominant COVID-19 complications were respiratory failure (100%), pulmonary edema (96%), multi

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Yakovenko, O. K., O. G. Khanin, V. V. Lotysh, and S. L. Gryf. "CLINICAL FEATURES OF SEVERE COVID-19 WITH LETHAL OUTCOME IN VOLYN REGION RESIDENTS." Ukrainian Pulmonology Journal 29, no. 2 (2021): 16–24. http://dx.doi.org/10.31215/2306-4927-2021-29-2-16-24.

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On March, 11 2020 WHO declared novel SARS-CoV-2 outbreak as pandemic (Coronavirus disease, COVID-19), which took away almost 4 million lives of our planet population. Management of severe COVID-19 represents the most challenging problem being associated with high level of mortality. Aim of the study: to assess the clinical features of severe COVID-19, demographic factors, laboratory markers and lung pathology findings associated with severe course and lethal outcome. Material and methods. In retrospective cohort survey we recruited 171 adult patients (age > 18 years) with severe COVID-19, a

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Amonotidi, A. V., A. S. Bulgakova, V. A. Boykov, et al. "Analysis of factors associated with a high probability of fatal case in patients with new coronavirus infection (COVID-19) treated in hospital." Siberian Journal of Clinical and Experimental Medicine 40, no. 1 (2025): 187–98. https://doi.org/10.29001/2073-8552-2025-40-1-187-198.

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Introduction. Due to the severity of the state and course of the new coronavirus infection (COVID-19), patients requiring hospitalization were the group at high risk of death during the spread of infection. Their condition, treatment tactics and outcomes were associated with the presence of comorbidities, gender, age and duration of hospitalization. Studying the relationship of these factors with mortality among patients with COVID-19 is essential for effective organization of medical care.Aim: To analyze factors associated with a high probability of mortality in patients with COVID-19 treated

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Venclovas, Zilvinas, Aurelija Alksnyte, Urte Rimsaite, Tomas Navickis, Mindaugas Jievaltas, and Daimantas Milonas. "Primary Renal Angiosarcoma: Rare Tumour with Lethal Outcomes." Medicina 60, no. 6 (2024): 885. http://dx.doi.org/10.3390/medicina60060885.

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Introduction: Renal haemangioma is a benign tumour, and due to its characteristics, it must be distinguished from malignant diseases. We present a clinical case of primary renal angiosarcoma initially mistaken for haemangioma due to their similarity. Case report: A 58-year-old man was admitted to the hospital with suspicion of pulmonary embolism. The patient complained of pain on the left side. An ultrasound and CT scan of the abdomen showed a tumour mass ~20.5 × 17.2 × 15.4 cm in size in the projection of the left kidney. On CT images, there were data for clear cell renal clear cell carcinoma

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Arutyunov, Gregory P., Ekaterina I. Tarlovskaya, Alexander G. Arutyunov, et al. "ACTIV SARS-CoV-2 registry (Analysis of Chronic Non-infectious Diseases Dynamics After COVID-19 Infection in Adult Patients). Assessment of impact of combined original comorbid diseases in patients with COVID-19 on the prognosis." Terapevticheskii arkhiv 94, no. 1 (2022): 32–47. http://dx.doi.org/10.26442/00403660.2022.01.201320.

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Aim. Study the impact of various combinations of comorbid original diseases in patients infected with COVID-19 later on the disease progression and outcomes of the new coronavirus infection. Materials and methods. The ACTIV registry was created on the Eurasian Association of Therapists initiative. 5,808 patients have been included in the registry: men and women with COVID-19 treated at hospital or at home. ClinicalTrials.gov ID NCT04492384. Results. Most patients with COVID-19 have original comorbid diseases (oCDs). Polymorbidity assessed by way of simple counting of oCDs is an ind

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Maksimov, Aleksandr V., and Vladimir A. Klevno. "Multifactorial Clinical and Anatomical Analysis of Lethal Outcome." Kuban Scientific Medical Bulletin 26, no. 6 (2019): 107–16. http://dx.doi.org/10.25207/1608-6228-2019-26-6-107-116.

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Aim. To establish signifi cant factors infl uencing the discrepancy of lifetime and postmortem diagnoses and to offer a technique of comparison of diagnoses when carrying out the clinical and anatomical analysis of a lethal outcome.Material and methods. The material for the study was 1420 acts of forensic examination of corpses recorded at the Bureau of forensic medical examination of the Moscow region during the 2014–2018 period. We studied the cases of deaths in hospitals of medical organisations with fi nal clinical diagnoses of the initial causes of death from diseases of the circulatory s

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Udovicic, Ivo, Maja Surbatovic, Goran Rondovic, et al. "Myeloid-derived suppressor cells in secondary sepsis: Is there an association with lethal outcome?" Vojnosanitetski pregled 77, no. 8 (2020): 773–83. http://dx.doi.org/10.2298/vsp180706133u.

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Background/Aim. Role of myeloid-derived suppressor cells (MDSCs) in human host response to sepsis still needs to be clarified. The aim of our study was to determine whether frequency and/or absolute numbers of the MDSCs were associated with outcome in critically ill patients with secondary sepsis and/or septic shock. Methods. Total of 40 critically ill patients with secondary sepsis were enrolled in a prospective study. We detected and enumerated both main subsets of MDSCs: granulocytic (G)-MDSCs and monocytic (M)- MDSCs on the Day 1 (the day of hospital admission) and the Day 5 after the. The

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Ragoucy-Sengler, C., and B. Pileire. "A biological index to predict patient outcome in paraquat poisoning." Human & Experimental Toxicology 15, no. 3 (1996): 265–68. http://dx.doi.org/10.1177/096032719601500315.

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1 In humans, the accidental or voluntary ingestion of paraquat, a non selective contact herbicide, is often lethal. Paraquat induces renal failure amongst other effects. 2 In this study we test the value of an index of the rate of increase in plasma creatinine over a 5 h period (dCreat/dt) to predict the outcome in intoxicated patients. These results are compared to previously published indices of severity of the paraquat poisoning. The proposed index is reliable, within the capability of any laboratory and will indicate the prognosis for poisoned patients within 6 h of admission to hospital.

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Adukauskienė, Dalia, Asta Mačiulienė, Aušra Čiginskienė, Agnė Adukauskaitė, and Justina Čyžiūtė. "Acute Subdural Hematoma after Isolated Traumatic Brain Injury: Risk Factors and Prediction of Mortality." Sveikatos mokslai 25, no. 2 (2015): 36–40. http://dx.doi.org/10.5200/sm-hs.2015.028.

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The aim of this study was to determine mortality and it‘s risk factors also prediction of lethal outcome in case of acute subdural hematoma after isolated traumatic brain injury (ITBI). Methods. A retrospective study of 162 patients after ITBI was carried out in Neurosurgical Intensive Care Unit (NITS) of Lithuanian University of Health Sciences Hospital (LUHSH) Kaunas Clinics (KC). Demographic (gender, age), clinical (pupil reaction to light, Glasgow Coma Scale (GCS) score, APACHE II scale score) and laboratory (white blood cell count, glycemia) data analysis on the first day after the injury

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Dushkin, A. D., P. O. Narusova, S. S. Andreev, et al. "Risk factors for adverse outcome in invasive candidiasis." Infekcionnye bolezni 23, no. 1 (2025): 65–72. https://doi.org/10.20953/1729-9225-2025-1-65-72.

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Invasive candidiasis, characterized by a severe course and high mortality, is one of the most common healthcare-associated infections. Objective. To determine the risk factors for lethal outcome in patients with invasive candidiasis and candidemia hospitalized in a multidisciplinary hospital in the city of Moscow in the period from 2020 to 2023. Patients and methods. A cohort single-center retrospective study was conducted, which included 169 patients with invasive candidiasis and candidemia aged 19 to 94 years, divided into 2 groups: favorable outcome (recolestation) and unfavorable (fatal) o

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Cvetanovska, Marija, Zvonko Milenkovik, Krsto Grozdanovski, Valerija Kirova Uroshevik, and Vlatko Cvetanovski. "The influence of comorbid factors in surviving of patients with severe form of seasonal influenza." Macedonian Pharmaceutical Bulletin 62, no. 1 (2016): 57–64. http://dx.doi.org/10.33320/maced.pharm.bull.2016.62.01.005.

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Elderly patients and patients with different comorbid conditions are at a higher risk of developing severe clinical course and lethal influenza outcome. The aim of this study was to define comorbid conditions in patients with a severe form of seasonal influenza, and to define their influence on lethal outcome. The study was a prospective, group comparison and was conducted at the University Clinic for Infectious Diseases in Skopje, Macedonia, during the period of January 01, 2012 to January 01, 2015. The study included 87 adult patients with a severe form of seasonal influenza, who were furthe

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Yin, Fufen, Mingrui Jin, Yujing Li, et al. "Externally validated nomogram for predicting short-term pregnancy outcome of singleton pregnancies with fetal growth restriction (FGR)." Gynecology and Obstetrics Clinical Medicine 4, no. 1 (2024): e000009. http://dx.doi.org/10.1136/gocm-2024-000009.

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ObjectiveThis study aimed at developing an available predictive model of singleton pregnancies with fetal growth restriction (FGR) for accurate and individualised prognosis assessment.MethodsThe prediction nomogram was developed by using multivariable Cox regression with data for 301 singleton FGR pregnancies at Peking University People’s Hospital. External validation was performed in 321 eligible singleton FGR pregnancies at the Affiliated Hospital of Qingdao University.ResultsAbsent umbilical arterial flow, fetal anomaly, history of abnormal pregnancy, non-cephalic presentation and history o

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Uchikov, Angel, Lyubomir Paunov, Atanas Batashki, et al. "Surgical treatment of pneumothorax in patients with COVID-19 – results and management." Folia Medica 63, no. 5 (2021): 663–69. http://dx.doi.org/10.3897/folmed.63.e69003.

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Introduction: The new coronavirus, SARS-CoV-2, provokes infection with different clinical presentation. It involves an asymptomatic condition, mild variants with fever and dry cough to severe pneumonia, adynamia and respiratory failure with lethal outcome. The fibrotic lung tissue after the inflammatory process is a background for development of a secondary pneumothorax. Although it rarely causes lethal outcomes in COVID-19 patients, pneumothorax requires early diagnosis and adequate treatment to prevent any complications and decrease mortality rate. Aim: The aim of this study was to analyse t

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Tsuchida, Takumi, Masaki Takahashi, Asumi Mizugaki, Hisashi Narita, and Takeshi Wada. "Differences in acute outcomes of suicide patients by psychiatric disorder: Retrospective observational study." Medicine 102, no. 38 (2023): e35065. http://dx.doi.org/10.1097/md.0000000000035065.

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Suicide is a social problem with significant economic losses, the victims of which are mainly from the productive population. There are numerous reports on the assessment of suicide risk, but most focus on long-term management. Therefore, factors influencing the severity of physical impairments in the acute phase and the prognosis of suicidal patients have not been sufficiently investigated. This is a single-center retrospective observational study. We collected data on suicidal patients admitted to our emergency department. The effect of age, gender, psychiatric history, method of suicide, al

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Abdullahu, Bajram, and Monika Belba. "Analyzing Mortality in Burned Patients with Lethal Area 50." Albanian Journal of Trauma and Emergency Surgery 6, no. 2 (2022): 1013–17. http://dx.doi.org/10.32391/ajtes.v6i2.272.

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Background; Clinical outcome is the most measurable of the critical care activity. Although every burn center has its own particular limitations, it is clear that exists a minimum standard of survival after burn injury which is LA50 (Lethal Area 50). The aim of this study is to present demographic and epidemiologic features of severe burns in Albania in the period 2009-2019 and to analyze burn mortality as an important outcome measure analyzing LA 50. Material and Methods; The study is retrospective clinical and analytical. Since our burn center is the only one in the country it en

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Abramova, N. N., I. S. Avrusin, O. P. Kozlova, et al. "Analysis of risk factors for lethal outcome in patients of pediatric intensive care units with immuno-inflammatory diseases." Messenger of ANESTHESIOLOGY AND RESUSCITATION 22, no. 2 (2025): 76–87. https://doi.org/10.24884/2078-5658-2025-22-2-76-87.

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Introduction. Systemic immune-inflammatory diseases can affect many systems and organs and have an extremely severe course with complications, causing multiple organ failure and death. Often, children with such diseases require hospitalization in the intensive care unit (ICU). For example, approximately 50% of patients with multisystem inflammatory syndrome, associated with COVID-19 in children (MIS-C) and systemic lupus erythematosus require hospitalization in the ICU.The objective was to determine risk factors for lethal outcome in children with immune-inflammatory diseases hospitalized in t

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Rugājs, Reinis, Monta Madelāne, Andrejs Ivanovs, and Ludmila Vīksna. "Overview and Outcomes of Patients Hospitalised with COVID-19 Pneumonia in Rīga East University Hospital." Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences. 78, no. 1 (2024): 10–15. http://dx.doi.org/10.2478/prolas-2024-0002.

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Abstract The COVID-19 pandemic is still a burden to the global health care system, affecting its capacity to maintain essential health services. Even though specific treatment and prevention options are available, the SARS-CoV-2 virus keeps accumulating mutations over time and challenging the efficiency of vaccines, causing new outbreaks and increasing hospitalisation. Early studies suggest that mortality from COVID-19 is increased by age and certain comorbidities. Thus, the goal of this study was to analyse patients hospitalised with COVID-19 pneumonia in terms of age, sex, and comorbidities.

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Cvetanovska, Marija, Zvonko Milenkovik, Valerija Kirova Uroshevik, Ilir Demiri, and Vlatko Cvetanovski. "Factors Associated with Lethal Outcome in Patients with Severe Form of Influenza." PRILOZI 37, no. 2-3 (2016): 63–72. http://dx.doi.org/10.1515/prilozi-2016-0018.

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Abstract Introduction: Clinical manifestations of influenza range from relatively mild and self-limiting respiratory infections to severe clinical manifestations with significant morbidity and mortality. The awareness of predictive indicators for the lethal outcome of influenza is of particular significance in making timely and exact decision for adequate treatment. The aim of this study was to identify the factors in patients with a severe form of influenza, resulting in lethal outcome. Materials and methods: The investigation was a prospective group comparison conducted at the University Cli

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Syed, Uneeba, Amna Rizvi, Syed Arsalan Hassan, Unaiza Syed, and Ifrah Syed. "Frequency of Covid Outcome in Covid Patients with Pre-Existing Different Co-Morbid Conditions." Pakistan Journal of Medical and Health Sciences 15, no. 10 (2021): 2534–36. http://dx.doi.org/10.53350/pjmhs2115102534.

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Background: Unexpectedly and unfortunately the end of the year 2019 has proved to be the start of a deadliest era of Coronavirus disease 19. Spread of this lethal disease has remained uninhibited so far. How rapidly it has wrapped up the whole world is dangerously alarming. Aim: To determine frequency of Covid outcome in Covid patients with preexisting different co-morbid conditions. Methods: This descriptive study was conducted from July 2020 to January 2021 in two tertiary care hospital i.e. Services hospital, Lahore (Punjab) and hospital, Quetta (Baluchistan). After ethical approval and inf

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Rosa, Regis G., Alexandre V. Schwarzbold, Rodrigo P. dos Santos, Eduardo E. Turra, Denise P. Machado, and Luciano Z. Goldani. "Vancomycin-ResistantEnterococcus faeciumBacteremia in a Tertiary Care Hospital: Epidemiology, Antimicrobial Susceptibility, and Outcome." BioMed Research International 2014 (2014): 1–6. http://dx.doi.org/10.1155/2014/958469.

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Vancomycin-resistantEnterococcus faecium(VREF) has emerged as a relevant multidrug-resistant pathogen and potentially lethal etiology of health care associated infections worldwide. The objective of this retrospective cohort study was to assess factors associated with mortality in patients with VREF bacteremia in a major tertiary referral hospital in Southern Brazil. All documented cases of bacteremia identified between May 2010 and July 2012 were evaluated. Cox regression was performed to determine whether the characteristics related to the host or antimicrobial treatment were associated with

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Zaraf'iants, G. N. "Forensic medical diagnostics of intoxication with certain poisonous mushrooms in the case of the lethal outcome in a hospital." Sudebno-meditsinskaya ekspertiza 59, no. 1 (2016): 22. http://dx.doi.org/10.17116/sudmed201659122-28.

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IVANTSOV, E. N., A. A. KHUSAINOVA, I. F. KHAMADULLINA, Z. F. KIM, and N. R. KHASANOV. "Time before primary percutaneous coronary intervention in patients with favorable and fatal outcomes due to ST-segment elevation myocardial infarction." Practical medicine 22, no. 6 (2024): 109–13. https://doi.org/10.32000/2072-1757-2024-6-109-113.

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ST-segment elevation myocardial infarction (STEMI) is an acute life-threatening condition that requires urgent, complex, well-coordinated treatment, aimed primarily at the earliest possible reperfusion. The adverse effect of delay to reperfusion on the prognosis of in-hospital mortality in patients with STEMI was demonstrated with both thrombolysis and PPCI in the 1996–2004 studies. More recent data are inconsistent regarding the association of adverse hospital outcomes with time to PPCI. The purpose was to examine the time from the onset of pain in ST-segment elevation myocardial infarction t

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Rovenskih, D. N., and S. A. Usov. "Pre-hospital management of traumatic hemorrhagic shock: lessons of modern warfare (a literature review)." Siberian Medical Review 5 (2021): 32–40. http://dx.doi.org/10.20333/25000136-2021-5-32-40.

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The review presents recommendations for pre-hospital management of traumatic haemorrhagic shock (PHMTHS), details of its performance, criteria for evaluation of efficacy and results of application. The main principles of PHMTHS developed during military activity of armed forces of the USA and their allies in Iraq and Afghanistan were: controlled hypotension, early infusion of tranexamic acid and the priority of blood loss replacement via transfusion. PHMTHS performed according to the stated principles leads to a significant decrease in the number of lethal outcome cases. This offers prospects

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Karonova, T. L., I. N. Korsakov, A. A. Mikhailova, et al. "An artificial intelligence approach for prognosis of COVID-19 course in hospitalized patients." Journal Infectology 15, no. 3 (2023): 60–66. http://dx.doi.org/10.22625/2072-6732-2023-15-3-60-66.

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Aim. To create algorithm and risk calculator for predicting the lethal outcome in patients with COVID-19.Materials and methods. Based on machine learning approach mortality risk calculator was developed in Almazov National Medical Research Centre using data of the hospitalised patients with an established diagnosis of COVID-19 (n=4071).Results. This mathematical model, which includes 11 significant features, has been proposed for estimation of fatal outcomes in the Clinical Infectious Hospital named after S.P. Botkin. Some key features were not assessed in most hospitals according to accepted

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Marwah, Sheeba, Kumari Usha Rani, and Archana Mishra. "An audit of extra-uterine pregnancy in a tertiary care facility in Northern India." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 11 (2017): 5025. http://dx.doi.org/10.18203/2320-1770.ijrcog20175020.

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Background: Ectopic pregnancy is the most frequent lethal gynaecological predicament, befalling worldwide in all strata of reproductive women. It remains the leading cause of pregnancy-related first trimester deaths. Though prompt diagnosis has furthered a decline in associated morbidity, an upsurge has been seen in its prevalence owing to a rise in predisposing risk factors. The objectives of this study were to identify incidence, risk factors, and outcome in patients presenting with ectopic pregnancy in a tertiary care hospital.Methods: This two-year retrospective study was conducted in Depa

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Vereshchagin, Alexey, and Ludmila Pavlovna Kotelnikova. "Results of the use of selective adsorption of endotoxin in the complex treatment of surgical sepsis and septic shock." Perm Medical Journal 38, no. 6 (2021): 16–24. http://dx.doi.org/10.17816/pmj38616-24.

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Objective. To estimate the results of the use of LPS-adsorption in the complex treatment of surgical or obstetric sepsis and septic shock and to determine the risk factors for the development of lethal outcomes. Materials and methods. Since 2014, twenty-nine patients with surgical or obstetric sepsis and septic shock have been treated at the Perm Regional Clinical Hospital using selective endotoxin adsorption in addition to conventional medical therapy. Endotoxin elimination was performed using hemoperfusion with the Alteco LPS Adsorber (Sweden). The patients were divided into two groups

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Fichtl, Maximilian Andreas, Sophia Anna Henne, Viktoria Bogner-Flatz, et al. "Prevalence and Potential Impact of Gastrointestinal Insufflation During Cardiopulmonary Resuscitation." Journal of Clinical Medicine 14, no. 7 (2025): 2511. https://doi.org/10.3390/jcm14072511.

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Background/Objectives: Insufflation of the gastrointestinal tract, as a side effect of improper ventilation, is a known complication in resuscitation patients. As animal studies have shown, this can be associated with an increase in intra-abdominal pressure with adverse effects on hemodynamics and respiratory mechanics. In this study, we investigated the prevalence and severity of insufflation and discussed the potential impact on the outcome of resuscitation. Methods: This study was based on computed tomography (CT) images from two university hospitals in Munich, Germany, which were taken as

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Żalińska, Agnieszka, Weronika Marcinkowska, Filip Gągorowski, et al. "Prenatal Diagnosis of Acrania in One Twin of a Dichorionic Diamniotic Pregnancy: A Case Report on Management and Perinatal Outcome." Reports 8, no. 2 (2025): 75. https://doi.org/10.3390/reports8020075.

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Background and Clinical Significance: Twin pregnancies are associated with an increased risk of congenital malformations. One of them is rare but lethal—acrania—which belongs to the group of neural tube defects. The pathogenesis of acrania is not fully understood. It is presumed that the underlying mechanism of its development is a disorder of migration of mesenchymal tissue. The presence of an acrania in one of the twins may lead to complications such as polyhydramnios, preterm labor, or, in severe cases, an intrauterine death in one or both twins. Case Presentation: A 30-year-old woman (G4P4

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Skopljanac, Ivan, Mirela Pavicic Ivelja, Danijela Budimir Mrsic, et al. "Can Lung Imaging Scores and Clinical Variables Predict Severe Course and Fatal Outcome in COVID-19 Pneumonia Patients? A Single-Center Observational Study." Life 12, no. 5 (2022): 735. http://dx.doi.org/10.3390/life12050735.

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COVID-19 prediction models mostly consist of combined clinical features, laboratory parameters, and, less often, chest X-ray (CXR) findings. Our main goal was to propose a prediction model involving imaging methods, specifically ultrasound. This was a single-center, retrospective cohort observational study of patients admitted to the University Hospital Split from November 2020 to May 2021. Imaging protocols were based on the assessment of 14 lung zones for both lung ultrasound (LUS) and computed tomography (CT), correlated to a CXR score assessing 6 lung zones. Prediction models for the neces

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McCormick, Meghan, James Zullo, and Ram Kalpatthi. "Epidemiology and Outcome of TRALI and TACO in the Pediatric Population: A Multi-Institutional Review." Blood 132, Supplement 1 (2018): 3811. http://dx.doi.org/10.1182/blood-2018-99-113959.

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Abstract Introduction: Transfusion of blood products can be associated with a wide variety of complications ranging in level of severity. The most lethal of these are Transfusion-Associated Circulatory Overload (TACO) and Transfusion-Related Acute Lung injury (TRALI). Over the five year period from 2012-2016, TRALI was the leading cause of transfusion-associated fatalities, closely followed by TACO. However, the incidence of these potentially lethal transfusion reactions in the pediatric population is not well known. Our objective is to describe the incidence of these transfusion reactions in

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Balasubramanian, Kavitha, Vinoth Kumar Sethuraman, Kandan Balamurugesan, and Stalin Viswanathan. "A retrospective study of clinical profile and outcome of patients with rodenticide poisoning in a tertiary care hospital." International Journal of Advances in Medicine 6, no. 2 (2019): 296. http://dx.doi.org/10.18203/2349-3933.ijam20190993.

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Background: In developing countries, the substances most commonly used for self-poisoning are agricultural pesticides including rodenticides. Authors aimed to assess the clinical status and outcomes of patients with rodenticide poisoning in a tertiary care hospital.Methods: This retrospective record-based study was carried over three years. Apart from demographic details, information regarding the time of ingestion, nature and amount of the compound. Other details included clinical features, complications, treatment and outcome of the patient. Descriptive analysis was carried out by the mean a

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Miller, Jena L., Ahmet A. Baschat, Mara Rosner, et al. "Neonatal Survival After Serial Amnioinfusions for Bilateral Renal Agenesis." JAMA 330, no. 21 (2023): 2096. http://dx.doi.org/10.1001/jama.2023.21153.

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ImportanceEarly anhydramnios during pregnancy, resulting from fetal bilateral renal agenesis, causes lethal pulmonary hypoplasia in neonates. Restoring amniotic fluid via serial amnioinfusions may promote lung development, enabling survival.ObjectiveTo assess neonatal outcomes of serial amnioinfusions initiated before 26 weeks’ gestation to mitigate lethal pulmonary hypoplasia.Design, Setting, and ParticipantsProspective, nonrandomized clinical trial conducted at 9 US fetal therapy centers between December 2018 and July 2022. Outcomes are reported for 21 maternal-fetal pairs with confirmed anh

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Sivkov, A. O., N. P. Shen, I. N. Leyderman, and O. G. Sivkov. "mNUTRIC score as a predictor of the lethal outcome in critically ill patients with COVID-19: systematic review and meta-analysis." Messenger of ANESTHESIOLOGY AND RESUSCITATION 20, no. 4 (2023): 54–60. http://dx.doi.org/10.24884/2078-5658-2022-20-4-54-60.

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The objective was to assess the predictive value of nutritive risk mNUTRIC score in relation to the lethal outcome in ICU patients suffering from COVID-19.Materials and methods. The systematic review and meta-analysis were performed based on the Preferred Reporting Items for Systematic and Meta-Analysis protocols. All observational (crossover and cohort) and prospective studies were included. The search was carried out in PubMed electronic database and was limited to 2019–2023. Conditions for inclusion into the study were: 1) a positive result of the SARS-CoV-2 polymerase chain reaction test;

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Kazantsev, Anton N., Konstantin P. Chernykh, Nona E. Zarkua, et al. "Immediate and long-term results of carotid endarterectomy in different periods of ischemic stroke." I.P. Pavlov Russian Medical Biological Herald 28, no. 3 (2020): 312–22. http://dx.doi.org/10.23888/pavlovj2020283312-322.

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Aim. Analysis of hospital and long-term results of carotid endarterectomy (CEA) in different periods of acute cerebrovascular event (ACVE). Materials and Methods. The given study was retrospective and was conducted using the method of patients sampling. In the period from 2010 to 2019, 1113 patients with ACVE in history who were later conducted CEA, were selected. Depending on the time interval between the last ACVE and CAE, all the patients were divided into 4 groups: the 1st group in the acutest period of ACVE (1-3 days) (n=24; 2.2%); the 2nd group in the acute period of ACVE (up to 28

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Jayakar, Sudhir R., and Prabhat B. Nichkaode. "Liver abscess, management strategies, and outcome." International Surgery Journal 5, no. 9 (2018): 3093. http://dx.doi.org/10.18203/2349-2902.isj20183729.

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Background: Liver abscess, a disease troubling mankind from ancient times, has earliest documentation in the Sanskrit document. Where right upper abdominal pain, have potentially lethal consequences, if prompt diagnosis and treatment are not accomplished. However, two major types are known, amoebic and pyogenic, in medical literature. Pyogenic liver abscess constitutes major bulk of hepatic abscess in western countries. The diagnosis is confirmed by ultrasonography, reddish brown (anchovy-paste like material) aspirate from abscess. The diagnosis, treatment and prognosis, of liver abscess have

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Rynda, A. Yu, O. A. Pavlov, O. P. Verbitsky, and M. Yu Podgornyak. "Emergency neurooncological care in patients with malignant tumors in a city hospital." Russian Neurosurgical Journal named after Professor A. L. Polenov 15, no. 3 (2023): 110–15. https://doi.org/10.56618/2071-2693_2023_15_3_110.

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ABSTRACT. Patients with malignant tumors are prone to a variety of neurological complications that require urgent evaluation and treatment.PURPOSE. To analyze the results of urgent neurosurgical interventions in the postoperative period in patients with malignant neurooncological pathology.MATERIALS AND METHODS. In total, the results of 63 patients who underwent emergency neurosurgical operations for complications of malignant oncological diseases from 2016 to 2022 at the St. Petersburg State Budgetary Institution of Healthcare “Mariinsky City Hospital” were analyzed. The analysis included inf

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Ramadhan, Yusriandi, Zainal Abidin, and Ardik Lahdimawan Lahdimawan. "Pediatric Air Gunshot Penetrating Head Injury with Good Outcome: A Case Report." Berkala Kedokteran 16, no. 2 (2020): 119. http://dx.doi.org/10.20527/jbk.v16i2.9225.

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Abstract: Ball bearing (BB) and pellet guns are non-power guns but their related injuries have been reported worldwide. They represent a significant cause of injury especially among children and teenagers. Their potentially harmful and lethal effects have been well documented in the medical literature since the early 1980s. Fatality rate is closely related to the damaged part of the brain and the level of the damage. In this Case Report we documented a 6-years-old girl was getting shot at the head by herself, who initially want to play around, using her neighbour’s Air gun rifle. The pellet tr

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Ivankova, E. O., V. V. Darvin, and M. A. Bessmertnykh. "Evaluation of the immediate and long-term results of endovascular treatment of ruptured vertebrobasilar artery aneurysms in an acute period of hemorrhage." Russian journal of neurosurgery 20, no. 4 (2019): 31–37. http://dx.doi.org/10.17650/1683-3295-2018-20-4-31-37.

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The study objective is to evaluate the results of endovascular treatment of patients with subarachnoid hemorrhage due to rupture of the vertebrobasilar artery aneurysm.Materials and methods. From 2011 to 2017, 26 patients underwent endovascular occlusion of the ruptured vertebrobasilar artery aneurysm in an acute period of hemorrhage in Surgut Clinical Hospital for Traumatology.Results. Endovascular interventions were performed in 1–14 days after the episode of the primary subarachnoid hemorrhage. Among the patients 53.8 % were in good condition at admission (Hunt–Hess grade I–II), 46.2 % had

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Baelum, Jens Kristian, Espen Ellingsen Moe, Mads Nybo, and Pernille Just Vinholt. "Venous Thromboembolism in Patients With Thrombocytopenia: Risk Factors, Treatment, and Outcome." Clinical and Applied Thrombosis/Hemostasis 23, no. 4 (2015): 345–50. http://dx.doi.org/10.1177/1076029615613158.

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Background: Venous thromboembolism (VTE) is a frequent and potentially lethal condition. Venous thrombi are mainly constituted of fibrin and red blood cells, but platelets also play an important role in VTE formation. Information about VTE in patients with thrombocytopenia is, however, missing. Objectives: To identify VTE risk factors and describe treatment and outcome (bleeding episodes and mortality) in patients with thrombocytopenia. Patients/Methods: Patients with thrombocytopenia (platelet count <100 × 109/L) admitted to Odense University Hospital, Denmark, between April 2000 and April

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C., Rekha, Rajagopal Meera, Latha Sree K., Kanyakumari Dheeravath, and Sushma Jagannagari. "A Study of Lethal Congenital Anomalies Undergoing Termination of Pregnancy at a Tertiary Care Hospital." International Journal of Pharmaceutical and Clinical Research 14, no. 12 (2022): 279–89. https://doi.org/10.5281/zenodo.13211070.

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<strong>Background: </strong>India does not have national birth defects surveillance in spite of congenital anomalies causing significant neonatal and foetal mortality. There is paucity of data regarding lethal congenital anomalies which are mostly diagnosed late in pregnancy making their termination risky to pregnant women. <strong>Aims and objectives: </strong>This study was conducted in pregnant women who underwent termination of pregnancy, for lethal congenital anomaly in foetus, to find their demographic and clinical profile, types of congenital malformations, risk factors

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Kamble, Neha B., Surekha N. Khandale, and Shreya U. Dahiwade. "Eclampsia is still a nightmare for obstetrician-maternal and perinatal outcome in eclampsia patients at tertiary hospital and factors affecting the outcome." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 14, no. 6 (2025): 1801–7. https://doi.org/10.18203/2320-1770.ijrcog20251565.

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Background: Among the disorders that complicate pregnancy, pre-eclampsia and eclampsia are major causes of maternal and perinatal morbidity and mortality. Hypertensive disorders complicate 5% to 10% of all pregnancies and form a lethal trio with haemorrhage and infection. In India, the incidence of eclampsia ranges from 1 in 500 to 1 in 30 (0.5%-1.8%). Pre-eclampsia and eclampsia are a major cause of approximately 20% of all maternal deaths in USA and around half of them are associated with eclampsia. To study various factors associated with eclampsia and outcomes in eclampsia patients. Method

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Šundalić, Sara, Iva Košuta, Ivana Baršić Lapić, et al. "Interleukin-6 and Leukocyte Cell Population Data in Newly Diagnosed Sepsis—A Prospective Study." Medicina 61, no. 3 (2025): 468. https://doi.org/10.3390/medicina61030468.

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Background and Objectives: Sepsis still represents a syndrome with a high mortality. A timely sepsis diagnosis and an early intervention are crucial for the disease outcomes. Sepsis-associated acute kidney injury (SA-AKI) is highly prevalent but often diagnosed late. We aimed to investigate whether serum interleukin-6 (IL-6) and leukocyte cell population data (CPD) could be adequate biomarkers for the prediction of survival and SA-AKI development. Materials and Methods: We conducted a prospective observational study in a medical intensive care unit of a tertiary hospital centre in Zagreb, Croa

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