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Journal articles on the topic 'In Situ Product Recovery'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Ng, Yuen Ling, and Yi Yang Kuek. "In-situ Product Recovery as a Strategy to Increase Product Yield and Mitigate Product Toxicity." Open Biotechnology Journal 7, no. 1 (2013): 15–22. http://dx.doi.org/10.2174/1874070701307010015.

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Product inhibition is often the cause limiting the maximum product concentration attainable in fermentation. This study showed the product yield of p-cresol could be improved by in-situ product recovery (ISPR). Escherichia coli transformed with the hpd BCA operon from Clostridium difficile was shown in this study to express phydroxyphenylacetate decarboxylase which converted p-hydroxyphenylacetate into p-cresol under anaerobic fermentation. Toxicity of p-cresol found at a concentration as low as 5 mM in a broth spiked with p-cresol was shown to have limited the maximum product concentration at

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2

Saboe, Patrick O., Lorenz P. Manker, William E. Michener, et al. "In situ recovery of bio-based carboxylic acids." Green Chemistry 20, no. 8 (2018): 1791–804. http://dx.doi.org/10.1039/c7gc03747c.

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3

Kaur, Guneet, A. K. Srivastava, and Subhash Chand. "Debottlenecking product inhibition in 1,3-propanediol fermentation by In-Situ Product Recovery." Bioresource Technology 197 (December 2015): 451–57. http://dx.doi.org/10.1016/j.biortech.2015.08.101.

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4

Bechtold, Matthias, and Sven Panke. "In situ Product Recovery Integrated with Biotransformations." CHIMIA International Journal for Chemistry 63, no. 6 (2009): 345–48. http://dx.doi.org/10.2533/chimia.2009.345.

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5

Carstensen, Frederike, Christian Marx, João André, Thomas Melin, and Matthias Wessling. "Reverse-flow diafiltration for continuous in situ product recovery." Journal of Membrane Science 421-422 (December 2012): 39–50. http://dx.doi.org/10.1016/j.memsci.2012.06.034.

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6

Silbiger, E., та A. Freeman. "Continuous Δ1-hydrocortisone dehydrogenation with in situ product recovery". Enzyme and Microbial Technology 13, № 11 (1991): 869–72. http://dx.doi.org/10.1016/0141-0229(91)90102-g.

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7

McClure, Dale D., Zhaohui Zheng, Guanyu Hu, and John M. Kavanagh. "Towards in situ product recovery for bubble column bioreactors." Chemical Engineering Journal 393 (August 2020): 124745. http://dx.doi.org/10.1016/j.cej.2020.124745.

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8

Nielsen, David R., and Kristala Jones Prather. "In situ product recovery ofn-butanol using polymeric resins." Biotechnology and Bioengineering 102, no. 3 (2009): 811–21. http://dx.doi.org/10.1002/bit.22109.

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9

Weilnhammer, Christian, and Eckhart Blass. "Continuous fermentation with product recovery by in-situ extraction." Chemical Engineering & Technology 17, no. 6 (1994): 365–73. http://dx.doi.org/10.1002/ceat.270170602.

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10

Carstensen, Frederike, Andreas Apel, and Matthias Wessling. "In situ product recovery: Submerged membranes vs. external loop membranes." Journal of Membrane Science 394-395 (March 2012): 1–36. http://dx.doi.org/10.1016/j.memsci.2011.11.029.

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11

Kwon, I. C., Y. J. Yoo, J. H. Lee, and J. O. Hyun. "Enhancement of taxol production by in situ recovery of product." Process Biochemistry 33, no. 7 (1998): 701–7. http://dx.doi.org/10.1016/s0032-9592(98)00037-5.

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12

Kaur, Guneet, and Kathy Elst. "Development of reactive extraction systems for itaconic acid: a step towards in situ product recovery for itaconic acid fermentation." RSC Adv. 4, no. 85 (2014): 45029–39. http://dx.doi.org/10.1039/c4ra06612j.

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Process optimization by integration of bioconversion with product separation and recovery i.e. in situ product recovery (ISPR) is an important means to develop a sustainable and petrochemical-competitive biotechnological method for itaconic acid production.

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13

Saboe, Patrick O., Hanna R. Monroe, William E. Michener, et al. "In situ product recovery of bio-based ethyl esters via hybrid extraction-distillation." Green Chemistry 21, no. 19 (2019): 5306–15. http://dx.doi.org/10.1039/c9gc01844a.

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14

Salas‐Villalobos, Ulises A., Rígel V. Gómez‐Acata, Josefina Castillo‐Reyna, and Oscar Aguilar. "In situ product recovery as a strategy for bioprocess integration and depletion of inhibitory products." Journal of Chemical Technology & Biotechnology 96, no. 10 (2021): 2735–43. http://dx.doi.org/10.1002/jctb.6797.

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15

Pérez-Bibbins, B., H. Gonzalez Peñas, E. Toth, V. Coupard, and N. Lopes-Ferreira. "Hybrid in situ product recovery technique applied to (A)IBE fermentation." Process Biochemistry 65 (February 2018): 21–27. http://dx.doi.org/10.1016/j.procbio.2017.10.015.

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16

Lee, Sang-Hyun, Moon-Ho Eom, Jin-Dal-Rae Choi, et al. "Ex situ product recovery for enhanced butanol production by Clostridium beijerinckii." Bioprocess and Biosystems Engineering 39, no. 5 (2016): 695–702. http://dx.doi.org/10.1007/s00449-016-1550-8.

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17

Chen, Xi, Rui Katahira, Zheng Ge, et al. "Microbial electrochemical treatment of biorefinery black liquor and resource recovery." Green Chemistry 21, no. 6 (2019): 1258–66. http://dx.doi.org/10.1039/c8gc02909a.

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18

Carstensen, F., T. Kasperidus, and M. Wessling. "Overcoming the drawbacks of microsieves with micromeshes for in situ product recovery." Journal of Membrane Science 436 (June 2013): 16–27. http://dx.doi.org/10.1016/j.memsci.2013.01.017.

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19

Groot, W. J., and K. Ch A. M. Luyben. "In situ product recovery by adsorption in the butanol/isopropanol batch fermentation." Applied Microbiology and Biotechnology 25, no. 1 (1986): 29–31. http://dx.doi.org/10.1007/bf00252508.

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20

Meier, Kristina, Frederike Carstensen, Christoph Scheeren, Lars Regestein, Matthias Wessling, and Jochen Büchs. "In situ product recovery of single-chain antibodies in a membrane bioreactor." Biotechnology and Bioengineering 111, no. 8 (2014): 1566–76. http://dx.doi.org/10.1002/bit.25220.

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21

Aguilar, Francisco, Thomas Scheper, and Sascha Beutel. "Improved Production and In Situ Recovery of Sesquiterpene (+)-Zizaene from Metabolically-Engineered E. coli." Molecules 24, no. 18 (2019): 3356. http://dx.doi.org/10.3390/molecules24183356.

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The sesquiterpene (+)-zizaene is the direct precursor of khusimol, the main fragrant compound of the vetiver essential oil from Chrysopogon zizanioides and used in nearly 20% of men’s fine perfumery. The biotechnological production of such fragrant sesquiterpenes is a promising alternative towards sustainability; nevertheless, product recovery from fermentation is one of the main constraints. In an effort to improve the (+)-zizaene recovery from a metabolically-engineered Escherichia coli, we developed an integrated bioprocess by coupling fermentation and (+)-zizaene recovery using adsorber ex

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22

van den Berg, Corjan, Nick Wierckx, Johan Vente, Paul Bussmann, Jan de Bont, and Luuk van der Wielen. "Solvent-impregnated resins as an in situ product recovery tool for phenol recovery fromPseudomonas putida S12TPL fermentations." Biotechnology and Bioengineering 100, no. 3 (2008): 466–72. http://dx.doi.org/10.1002/bit.21790.

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23

Tönjes, Sinah, Evelien Uitterhaegen, Ilse Palmans, et al. "Metabolic Engineering and Process Intensification for Muconic Acid Production Using Saccharomyces cerevisiae." International Journal of Molecular Sciences 25, no. 19 (2024): 10245. http://dx.doi.org/10.3390/ijms251910245.

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The efficient production of biobased organic acids is crucial to move to a more sustainable and eco-friendly economy, where muconic acid is gaining interest as a versatile platform chemical to produce industrial building blocks, including adipic acid and terephthalic acid. In this study, a Saccharomyces cerevisiae platform strain able to convert glucose and xylose into cis,cis-muconic acid was further engineered to eliminate C2 dependency, improve muconic acid tolerance, enhance production and growth performance, and substantially reduce the side production of the intermediate protocatechuic a

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24

Iyyappan, J., G. Baskar, B. Bharathiraja, and M. Gopinath. "Enhanced malic acid production using Aspergillus niger coupled with in situ product recovery." Bioresource Technology 308 (July 2020): 123259. http://dx.doi.org/10.1016/j.biortech.2020.123259.

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25

Marques, M. P. C., P. Fernandes, J. M. S. Cabral, P. Žnidaršič-Plazl, and I. Plazl. "On the feasibility of in situ steroid biotransformation and product recovery in microchannels." Chemical Engineering Journal 160, no. 2 (2010): 708–14. http://dx.doi.org/10.1016/j.cej.2010.03.056.

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26

Zhou, Z., Z. Yao, H. Q. Wang, H. Xu, P. Wei, and P. K. Ouyang. "Improved enzymatic synthesis of N-carbamoyl-D-phenylalanine with in situ product recovery." Biotechnology and Bioprocess Engineering 16, no. 3 (2011): 611–16. http://dx.doi.org/10.1007/s12257-010-0334-2.

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27

Pahl, James W., Irving A. Mendelssohn, and Thomas J. Hess. "Recovery of a Louisiana Coastal Marsh 3 Years After In Situ Burning of a Hydrocarbon Product Spill." International Oil Spill Conference Proceedings 1999, no. 1 (1999): 1279–82. http://dx.doi.org/10.7901/2169-3358-1999-1-1279.

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ABSTRACT The high degree of physical disturbance associated with conventional response options to oil spills in wetlands is driving the investigation of alternative cleanup methodologies. In March 1995, a spill of gas condensate product onto a brackish marsh at Rockefeller Wildlife Refuge in southwestern Louisiana was removed through the use of in situ burning. A monitoring program was initiated to examine three treatment marshes: (1) condensate-impacted and burned, (2) condensate-impacted and unburned, and (3) a reference that was neither exposed to the condensate nor burned. The authors comp

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28

Ramos-Suarez, Maria, Yue Zhang, and Victoria Outram. "Current perspectives on acidogenic fermentation to produce volatile fatty acids from waste." Reviews in Environmental Science and Bio/Technology 20, no. 2 (2021): 439–78. http://dx.doi.org/10.1007/s11157-021-09566-0.

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AbstractVolatile fatty acids (VFAs) are key platform chemicals used in a multitude of industries including chemicals, pharmaceuticals, food and agriculture. The current route for VFA production is petrochemical based. VFAs can be biologically produced using organic wastes as substrate, therefore directly contributing to a sustainable economy. This process is commonly known as acidogenic fermentation (AF). This review explores the current research on the development of AF processes optimized for VFA production. Three process steps are considered: feedstock pretreatment, fermentation, and primar

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29

Fu, Haoyang, Tingting Zhou, and Chenglin Sun. "Evaluation and Analysis of AMSR2 and FY3B Soil Moisture Products by an In Situ Network in Cropland on Pixel Scale in the Northeast of China." Remote Sensing 11, no. 7 (2019): 868. http://dx.doi.org/10.3390/rs11070868.

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An in situ soil moisture observation network at pixel scale is constructed in cropland in the northeast of China for accurate regional soil moisture evaluations of satellite products. The soil moisture products are based on the Japan Aerospace Exploration Agency (JAXA) algorithm and the Land Parameter Retrieval Model (LPRM) from the Advanced Microwave Scanning Radiometer 2 (AMSR2), and the products from the FengYun-3B (FY3B) satellite are evaluated using synchronous in situ data collected by the EC-5 sensors at the surface in a typical cropland in the northeast of China during the crop-growing

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30

Pahl, James W., Irving A. Mendelssohn, and Thomas J. Hess. "THE APPLICATION OF IN-SITU BURNING TO A LOUISIANA COASTAL MARSH FOLLOWING A HYDROCARBON PRODUCT SPILL: PRELIMINARY ASSESSMENT OF SITE RECOVERY." International Oil Spill Conference Proceedings 1997, no. 1 (1997): 823–28. http://dx.doi.org/10.7901/2169-3358-1997-1-823.

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ABSTRACT The high degree of physical disturbance associated with conventional responses to oil spills in wetlands is driving the search for alternative cleanup methodologies. In March 1995, in southwestern Louisiana, a spill of gas condensate product into a brackish marsh at Rockefeller Wildlife Refuge was removed by in-situ burning. A monitoring program was established to examine the recovery of the marsh site. Three treatments were examined: (1) condensate-impacted and burned, (2) condensate-impacted and unburned, and (3) a reference that was neither exposed to the condensate nor burned. In

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31

Halka, Lisa, and Rolf Wichmann. "Enhanced Production and in situ Product Recovery of Fusicocca-2,10(14)-Diene from Yeast." Fermentation 4, no. 3 (2018): 65. http://dx.doi.org/10.3390/fermentation4030065.

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Fusicocca-2,10(14)-diene (FCdiene) is a tricyclic diterpene which has many pharmaceutical applications, for example, it is a precursor for different anticancer drugs, including fusicoccin A. Chemical synthesis of this diterpene is not economical as it requires 14 steps with several stereospecific reactions. FCdiene is naturally produced at low titers in phytopathogenic filamentous fungi. However, production of FCdiene can be achieved via expression of fusicoccadiene synthase in yeast. The objective of this study is to increase FCdiene production by optimizing the yeast fermentation process. Ou

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32

Bueno-Zabala, K. A., C. G. Lopresto, V. Calabro, S. Curcio, A. A. Ruiz-Colorado, and S. Chakraborty. "Optimized Production of Glucose Syrup and Enzyme Membrane Reactor Using In Situ Product Recovery." Industrial & Engineering Chemistry Research 59, no. 49 (2020): 21305–11. http://dx.doi.org/10.1021/acs.iecr.0c04636.

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33

Xue, Chuang, Fangfang Liu, Mengmeng Xu, et al. "Butanol production in acetone-butanol-ethanol fermentation with in situ product recovery by adsorption." Bioresource Technology 219 (November 2016): 158–68. http://dx.doi.org/10.1016/j.biortech.2016.07.111.

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34

Mengers, Hendrik G., William Graf von Westarp, Daniela Brücker, Andreas Jupke, and Lars M. Blank. "Yeast-based production and in situ purification of acetaldehyde." Bioprocess and Biosystems Engineering 45, no. 4 (2022): 761–69. http://dx.doi.org/10.1007/s00449-022-02697-w.

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AbstractAcetaldehyde is a platform chemical with a production volume of more than 1 Mt/a, but is chiefly synthesized from petrochemical feedstocks. We propose the fermentative conversion of glucose towards acetaldehyde via genetically modified S. cerevisiae. This allows for ethanol-free bioactaldehyde production. Exploiting the high volatility of the product, in situ gas stripping in an aerated reactor is inevitable and crucial due to the respiratory toxicity effects of the acetaldehyde overproduction. We devise a lab-scale setup for the recovery of the product from the off-gas. Water was chos

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35

De Brabander, Pieter, Evelien Uitterhaegen, Ellen Verhoeven, Cedric Vander Cruyssen, Karel De Winter, and Wim Soetaert. "In Situ Product Recovery of Bio-Based Industrial Platform Chemicals: A Guideline to Solvent Selection." Fermentation 7, no. 1 (2021): 26. http://dx.doi.org/10.3390/fermentation7010026.

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In situ product recovery (ISPR), in the form of an extractive fermentation process, can increase productivity and product titers in the sustainable production of platform chemicals. To establish a guideline for the development of industrially relevant production processes for such bio-based compounds, a wide screening was performed, mapping the potential of an extensive range of solvents and solvent mixtures. Besides solvent biocompatibility with Saccharomyces cerevisiae, distribution coefficients of three organic acids (protocatechuic acid, adipic acid and para-aminobenzoic acid) and four fra

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36

Lee, Sang-Hyun, Moon-Ho Eom, Sooah Kim, et al. "Ex situ product recovery and strain engineering of Clostridium acetobutylicum for enhanced production of butanol." Process Biochemistry 50, no. 11 (2015): 1683–91. http://dx.doi.org/10.1016/j.procbio.2015.08.010.

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37

Van Hecke, Wouter, Guneet Kaur, and Heleen De Wever. "Advances in in-situ product recovery (ISPR) in whole cell biotechnology during the last decade." Biotechnology Advances 32, no. 7 (2014): 1245–55. http://dx.doi.org/10.1016/j.biotechadv.2014.07.003.

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38

Yun, Boreum, Su-Hwan Cheon, Mi-Na Song, Ji-Yeon Han, and Dong-Il Kim. "Increased production of hctla4ig using in situ product recovery in transgenic rice cell suspension cultures." Journal of Biotechnology 136 (October 2008): S135. http://dx.doi.org/10.1016/j.jbiotec.2008.07.287.

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39

Xue, Chuang, Jingbo Zhao, Fangfang Liu, Congcong Lu, Shang-Tian Yang, and Feng-Wu Bai. "Two-stage in situ gas stripping for enhanced butanol fermentation and energy-saving product recovery." Bioresource Technology 135 (May 2013): 396–402. http://dx.doi.org/10.1016/j.biortech.2012.07.062.

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40

Millette, D., F. Falkiewicz, E. Zamberlan, et al. "Development of a Soil, Surface-Water, and Groundwater Remediation Program for the Accidental Crude-Oil Spill that Occurred on July 16, 2000 at the Petrobras Refinery Refinaria Presidente GetúLio Vargas-Repar, Araucária, Brazil – PR." International Oil Spill Conference Proceedings 2003, no. 1 (2003): 403–8. http://dx.doi.org/10.7901/2169-3358-2003-1-403.

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ABSTRACT On July 16, 2000, a crude oil spill occurred at the PETROBRAS refinery Refinaria Presidente Getúlio Vargas-REPAR, located in Araucária, PR, Brazil. A significant quantity of oil was retained within an area known as Ponto 0, between the spill site and Rio Barigüi, contaminating the hanks of a small stream (Arroio Saldanha), the soil adjacent to the stream, and the soil of four small wetlands, over a distance of 2 km. This paper presents an overview of the remediation program for Ponto 0, and draws preliminary conclusions regarding the efficacy of different remediation technologies. The

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41

WALKER, RICHARD L., LEON H. JENSEN, HAILU KINDE, AMY V. ALEXANDER, and LINDA S. OWENS. "Environmental Survey for Listeria Species in Frozen Milk Product Plants in California." Journal of Food Protection 54, no. 3 (1991): 178–82. http://dx.doi.org/10.4315/0362-028x-54.3.178.

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A survey of frozen milk product (FMP) plants in California was conducted to determine prevalence of Listeria spp. among plants and within specific areas in plants. Association of possible factors contributing to the presence of Listeria was analyzed. Of 922 samples, 111 (12%) were positive for Listeria spp. Listeria monocytogenes and L. innocua were the only species isolated. Of 39 plants sampled, L. monocytogenes was the only species recovered from 5 (12.8%) plants and L. innocua was the only species recovered from 13 (33.3%) plants. Both species were isolated from 9 (23.1%) plants. No Lister

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42

Bernardino, Ana R. S., Cristiana A. V. Torres, João G. Crespo, and Maria A. M. Reis. "Assessment of in situ product recovery techniques to enhance 2-phenylethanol production by Acinetobacter soli ANG344B." Biochemical Engineering Journal 212 (December 2024): 109508. http://dx.doi.org/10.1016/j.bej.2024.109508.

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43

Che, Kai, Xiaoyang Zhu, Guangshi Tang, Man Zhao, and Junqing Pan. "In Situ Electroplating of Ir@Carbon Cloth as High-Performance Selective Oxygen Evolution Reaction Catalyst for Direct Electrolytic Recovery of Lead." Catalysts 13, no. 2 (2023): 322. http://dx.doi.org/10.3390/catal13020322.

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The hydrometallurgical technology provides an efficient and sustainable green lead recovery process from lead acid batteries. Methanesulfonic acid has been widely considered as a green solvent for lead electrolytic recovery. However, the competitive precipitation of PbO2 at anode and higher overpotential for OER limit the lead recovery efficiency. In this work, an anodic oxygen evolution reaction (OER) catalyst with a low Ir mass fraction of 7.2% is obtained by electroplating iridium on carbon cloth (CC), exhibiting a lower overpotential of 256 mV, longer lifetime of 10 h, and better stability

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44

Huda, Md Sanaul, and Nurun Nahar. "Oil Recovery from Dry Grind Ethanol Plant Coproducts Using Ethanol." Processes 9, no. 12 (2021): 2282. http://dx.doi.org/10.3390/pr9122282.

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Corn ethanol bio-refineries are seeking economic processing strategies for recovering oil from their coproducts. The addition of ethanol can be an efficient method to recover the oil from the coproducts as the industry has available ethanol. This study considered the effects of ethanol on oil recovery from distillers’ dried grains with solubles (DDGS) and oil partitioning from whole stillage (WS) on a laboratory scale. Ethanol was added with original and heavier fraction DDGS in different temperatures (room temperature ~20 °C, 30 °C, 40 °C, and 50 °C) and solids loadings (20%, 30%, and 40%), a

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45

McNally, Joseph T., Craig G. Robertson, and Ned E. Wehler. "CONTAINMENT AND REMOVAL OF FUEL OIL FROM GROUNDWATER BENEATH A DENSELY POPULATED HOUSING DEVELOPMENT." International Oil Spill Conference Proceedings 1985, no. 1 (1985): 267–71. http://dx.doi.org/10.7901/2169-3358-1985-1-267.

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ABSTRACT A leak from a buried pipeline resulted in the loss of approximately 30,000 gallons of No. 2 fuel oil beneath a housing development in suburban New Castle County, Delaware. After seeping to the water table, the resultant hydrocarbon plume threatened the homes as well as a downgradient stream and an irrigation pond. Site geology consisted of a highly-weathered metamorphic rock overlain by varying thicknesses of fill material. A steep water table gradient existed; the depth to the water table ranged between 6 and 17 feet below grade. Two-inch monitoring wells were installed in public eas

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46

Kaur, Guneet, Miranda Maesen, Linsey Garcia-Gonzalez, Heleen De Wever, and Kathy Elst. "Novel Intensified Back Extraction Process for Itaconic Acid: Toward in Situ Product Recovery for Itaconic Acid Fermentation." ACS Sustainable Chemistry & Engineering 6, no. 6 (2018): 7403–11. http://dx.doi.org/10.1021/acssuschemeng.7b04874.

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47

Buque-Taboada, Evelyn M., Adrie J. J. Straathof, Joseph J. Heijnen, and Luuk A. M. van der Wielen. "In situ product recovery (ISPR) by crystallization: basic principles, design, and potential applications in whole-cell biocatalysis." Applied Microbiology and Biotechnology 71, no. 1 (2006): 1–12. http://dx.doi.org/10.1007/s00253-006-0378-6.

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48

Ennis, B. M., C. T. Marshall, I. S. Maddox, and A. H. J. Paterson. "Continuous product recovery by in-situ gas stripping/condensation during solvent production from whey permeate usingClostridium acetobutylicum." Biotechnology Letters 8, no. 10 (1986): 725–30. http://dx.doi.org/10.1007/bf01032571.

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49

Mariano, Adriano Pinto, Nasib Qureshi, Rubens Maciel Filho, and Thaddeus Chukwuemeka Ezeji. "Bioproduction of butanol in bioreactors: New insights from simultaneous in situ butanol recovery to eliminate product toxicity." Biotechnology and Bioengineering 108, no. 8 (2011): 1757–65. http://dx.doi.org/10.1002/bit.23123.

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50

Volpe, G., S. Colella, V. Forneris, C. Tronconi, and R. Santoleri. "The Mediterranean Ocean Colour Observing System – system development and product validation." Ocean Science 8, no. 5 (2012): 869–83. http://dx.doi.org/10.5194/os-8-869-2012.

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Abstract. This paper presents the Mediterranean Ocean Colour Observing System in the framework of the growing demand of near real-time data emerging within the operational oceanography international context. The main issues related to the satellite operational oceanography are tied to the following: (1) the near real-time ability to track data flow uncertainty sources; (2) in case of failure, to provide backup solutions to end-users; and (3) to scientifically assess the product quality. We describe the major scientific and technological steps made to develop, maintain and improve the operation

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