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Relevant bibliographies by topics / In vitro biological evaluation

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Academic literature on the topic 'In vitro biological evaluation'

Author: Grafiati

Published: 15 June 2024

Last updated: 31 July 2025

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Journal articles on the topic "In vitro biological evaluation"

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Morais, Shabna Roupal, R. Ram Narayanan, K. P. Sushmitha, N. Suchithra, Shruti Shankar, and M. Sugumar. "In vitro Biological Evaluation of Acanthophora spicifera." Research Journal of Pharmacy and Technology 13, no. 10 (2020): 4777. http://dx.doi.org/10.5958/0974-360x.2020.00840.9.

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Sheema, Sheema, Salman Zafar Salman Zafar, Nazif Ullah Nazif Ullah, Ishaq khan Ishaq khan, and and Ghias ud din and Ghias ud din. "Phytochemical and In Vitro Biological Evaluation of Roots of Malvastrum coromandelianum (L.) Garcke." Journal of the chemical society of pakistan 45, no. 6 (2023): 568. http://dx.doi.org/10.52568/001399/jcsp/45.06.2023.

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Malvastrum coromandelianum (L.) Garcke is a medicinal plant, employed traditionally for the treatment of different human illnesses. This study has been planned to study the chemical and biological aspects of the roots of the plant, using chemical and instrumental analytical techniques. Standard reported protocols were used for phytochemical screening of the crude extract, indicating the presence of terpenoids, steroids, flavonoids, and alkaloids classes of compounds. The extract was analyzed through Gas Chromatography-Mass Spectrometry (GC-MS) to confirm the presence of specific phytochemicals

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Yusuf, Abdullah, Jiang-Yu Zhao, Paruke Aibibula, Ju-Bao Zhang, Guo-Zheng Huang, and Haji Akber Aisa. "Synthesis and in vitro Biological Evaluation of Cananodine." HETEROCYCLES 102, no. 3 (2021): 506. http://dx.doi.org/10.3987/com-20-14394.

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Halik, Paweł K., Przemysław Koźmiński, Joanna Matalińska, Piotr F. J. Lipiński, Aleksandra Misicka, and Ewa Gniazdowska. "In Vitro Biological Evaluation of Aprepitant Based 177Lu-Radioconjugates." Pharmaceutics 14, no. 3 (2022): 607. http://dx.doi.org/10.3390/pharmaceutics14030607.

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Currently, the search for promising NK1R-positive tumor-targeting radiopharmaceuticals based on the structure of small molecular antagonists of neurokinin-1 receptor can be observed. Following this trend, we continued our evaluation of aprepitant-based 177Lu-radioconjugates in terms of future oncological applications. For this purpose, three novel aprepitant homologues were synthesized to broaden the previously obtained derivative portfolio, functionalized with the DOTA chelator and labeled with 68Ga and 177Lu. The newly evaluated radioconjugates showed the intended significant increase in lip

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Yi, Jiling, Zheng Zhao, Shipu Li, Yixia Yin, and Xinyu Wang. "In vitro biological evaluation of graphene on neuronal cells." Journal of Wuhan University of Technology-Mater. Sci. Ed. 31, no. 4 (2016): 925–30. http://dx.doi.org/10.1007/s11595-016-1469-6.

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Rafaat, Mahmood Sherzad, Arzu Karatepe, Serhat Keser, Şule İnci, and Semih Dalkılıc. "In vitro Biological Evaluation of 1,2,4-triazole Mannich Base." BioMed Target Journal 1, no. 2 (2023): 22–30. http://dx.doi.org/10.59786/bmtj.123.

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Biological evaluation of a 1,2,4-triazole mannich base that has been synthesized for interesting behavior in medicinal chemistry, so it’s interesting to synthesize triazole derivatives and investigate their biological properties to evaluate their capacity in medicine. The aim of this study evaluate the antimicrobial, anticancer, and antioxidant activities of a 1,2,4-triazole Mannich base derivative and its power in the treatment of diseases. For antimicrobial activity four bacterial strains and one fungal strain based on the agar disc diffusion. While used two cancer cell lines for anticancer

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Ourhzif, El-Mahdi, Caroline Decombat, Isabelle Abrunhosa-Thomas, et al. "Synthesis and Biological Evaluation of New Naphthoquinones Derivatives." Current Organic Synthesis 17, no. 3 (2020): 224–29. http://dx.doi.org/10.2174/1570179417666200212111956.

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: New substituted 1,4-naphthoquinones have been prepared in good overall yields through the naphthol route. The cytotoxicity of these compounds was tested in vitro on MCF-7 breast tumor cells. The most active compound 14 displayed an IC50 of 15μM. Objective: To investigate the cytotoxicity of new naphthoquinones derivatives on MCF-7 cells. Methods: Synthesis of new naphtoquinones derivatives and in vitro evaluation of their cytotoxicity on MCF-7 cells (rezasurin cell-based assay). Results: Starting from Ethyl 4-hydroxy-6,7-dimethoxy-2-naphthoate, four naphthoquinones were prepared and exhibite

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Venkateshwarlu, R., B. Chinnababu, U. Ramulu, et al. "Synthesis and biological evaluation of (−)-kunstleramide and its derivatives." MedChemComm 8, no. 2 (2017): 394–404. http://dx.doi.org/10.1039/c6md00606j.

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Vaesken, Antoine, Christian Pidancier, Nabil Chakfe, and Frederic Heim. "Hybrid textile heart valve prosthesis: preliminary in vitro evaluation." Biomedical Engineering / Biomedizinische Technik 63, no. 3 (2018): 333–39. http://dx.doi.org/10.1515/bmt-2016-0083.

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Abstract Transcatheter aortic valve implantation (TAVI) is nowadays a popular alternative technique to surgical valve replacement for critical patients. Biological valve tissue has been used in these devices for over a decade now with over 100,000 implantations. However, material degradations due to crimping for catheter insertion purpose have been reported, and with only 6-year follow-up, no information is available about the long-term durability of biological tissue. Moreover, expensive biological tissue harvesting and chemical treatment procedures tend to promote the development of syntheti

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Abdul-Rida, Nabeel A., and Kawther M. Talib. "NEW CHALCONE DERIVATIVES AS ANTICANCER AND ANTIOXIDANT AGENTS: SYNTHESIS, MOLECULAR DOCKING STUDY AND BIOLOGICAL EVALUATION." Chemical Problems 22, no. 2 (2024): 177–86. http://dx.doi.org/10.32737/2221-8688-2024-2-177-186.

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In this approach, a series of new chalcone derivatives bearing baclofen drug were synthesized via Claisen-Schmidt condensation and evaluated in vitro as anticancer and antioxidant agents. The newly synthesized compounds were characterized by FT-IR, 1H-NMR, 13C-NMR spectra, and elemental analysis. All products were screened in vitro against both cell lines HdFn and MCF-7. The cytotoxicity assay results revealed that derivatives 5a and 5d exhibited good inhibition for cell lines MCF-7 with IC50 values 32.5 and 37.6 µM, respectively while 5a and 5c exhibited acceptable inhibition for HdFn with IC

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Dissertations / Theses on the topic "In vitro biological evaluation"

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Anissian, H. Lucas. "In vitro evaluation of hip prostheses /." Stockholm, 2001. http://diss.kib.ki.se/2001/20010420anis/.

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Ørskov, Christensen Janne. "Evaluation of an in vitro lipid digestion model : testing poorly soluble drug substances and lipid-based formulations /." [Cph.] : Department of Pharmaceutics, The Danish University of Pharmaceutical Sciences, 2004. http://www.dfh.dk/phd/defences/jannechristensen.htm.

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Poggialini, Federica. "Investigation of in vitro and in vivo pharmacokinetics and biological evaluation of pharmacologically active compounds." Doctoral thesis, Università di Siena, 2022. http://hdl.handle.net/11365/1202964.

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The first part of this thesis deals with the evaluation of in vitro and in vivo pharmacokinetics of novel broad-spectrum antiviral compounds active against enveloped viruses. The design and synthesis of new series of antiviral compounds with 1H-pyrrol-methylene thioxodihydropyrimidine structure, has been realized by Professor Maurizio Botta's research group, at the University of Siena. Compounds’ antiviral activity has been evaluated on several enveloped viruses, such as ZIKAV, DENV-2 and five influenza strains including the pandemic strain H7N9. The selectivity against enveloped viruses, time

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Machado, Michel Mansur. "Perfil fitoquímico e avaliação dos principais efeitos biológicos e imunológicos In Vitro da Euphorbia tirucalli L." Universidade Federal de Santa Maria, 2007. http://repositorio.ufsm.br/handle/1/5893.

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Today we can easily find the most diverse kind of information about a particular medicinal plant, but without scientific basis, making their use a potential risk to health. Overall, the findings on the safety and efficacy are based on precarious evaluations and popular use. There is a need for qualified professionals to access, critical analyze and assign such information in a way that it could be easily understood, not only by health professionals, but also by the users of these products. One example of these plants used in popular medicine, but without scientific evidence, is Euphorbia tiruc

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Bwalya, A. G. "Evaluation of the in vitro biological activities and phytochemical profiling of eight Ficus species collected in Zambia." Thesis, University College London (University of London), 2015. http://discovery.ucl.ac.uk/1457111/.

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Infectious diseases are responsible for an overwhelming number of deaths and morbidity worldwide. In tropical regions of the world, in particular, developing countries like Zambia, poor health is prevalent and diseases such as malaria, meningitis, pneumonia, tuberculosis and gastrointestinal infections strongly persist. Folkloric medicines are still actively used against some of these infections as primary care before seeking conventional treatment at hospitals. Members of the genus Ficus (Moraceae) are traditionally used in Zambia against many diseases caused by bacterial, fungal and protozoa

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PRENCIPE, Filippo. "Synthesis and biological evaluation in vitro and in vivo of novel potent anticancer agents affecting tubulin polymerization." Doctoral thesis, Università degli studi di Ferrara, 2017. http://hdl.handle.net/11392/2487939.

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L’attività di ricerca svolta durante i tre anni di dottorato ha avuto come obiettivo la progettazione, la sintesi e l’ottimizzazione di nuovi potenziali agenti antitumorali dotati di attività antiproliferativa e antivascolare che hanno come target biologico i microtubuli, strutture dinamiche cellulari generate dalla polimerizzazione di eterodimeri di α,β tubulina. Il sistema di microtubuli è essenziale per la divisione cellulare, essendo coinvolto nella formazione del fuso mitotico, ed è importante per diversi processi cellulari quali la regolazione della motilità, segnalazione cellulare, secr

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Galgano, Camillo. "Evaluation des propriétés biologiques et de scellement de 4 matériaux endodontiques = [In vitro evaluation of the biological and sealing properties of four endodontic sealers] /." Genève : [s.n.], 2005. http://www.unige.ch/cyberdocuments/theses2005/GalganoC/these.pdf.

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Hollywood, Jane Constance. "Biological control of late blight of potatoes : in vivo and in vitro evaluation of microbial antagonists against tuber blight." Thesis, University College London (University of London), 2004. http://discovery.ucl.ac.uk/1446592/.

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The cost of losses and control measures attributed to late blight of potatoes caused by Phytophthora infestans, are estimated to exceed $5 billion annually. Breeding for resistance is difficult owing to the tetraploid genotype of potato and current strains of the pathogen have developed resistance to chemical control. Consequently the search for biological control has assumed greater importance. In this investigation an in vivo bioassay was used to select soils antagonistic to late blight of potatoes, caused by Phytophthora infestans. Four out of eight samples demonstrated reproducible antagon

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Blanco, Carcache Peter Josephin. "Chemical Characterization and Biological Evaluation of Secondary Metabolites Isolated from Glycosmis ovoidea." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1580383951030389.

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Lolato, A. "FROM BENCH TO CHAIRSIDE: EVALUATION OF BIOLOGICAL EFFECTS OF PLATELET CONCENTRATES THROUGH AN IN-VITRO STUDY AND A RANDOMIZED CLINICAL TRIAL." Doctoral thesis, Università degli Studi di Milano, 2017. http://hdl.handle.net/2434/474332.

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Autologous platelet concentrates are widely used in a variety of medical application with the aim of enhancing the regeneration of hard and soft tissue. The rationale of this clinical use lies in their enriched content of growth factors and other key molecules involved in promoting tissue healing. This thesis is composed of two different studies having as a common objective the evaluation of the biological properties of a platelet concentrate, Pure-Platelet Rich Plasma. The first part of the thesis was a pre-clinical in vitro study focused on evaluating the stimulating activity of P-PRP on

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Books on the topic "In vitro biological evaluation"

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C, Sahu Saura, ed. Hepatotoxicity: From genomics to in vitro and in vivo models. John Wiley & Sons, 2007.

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C, Sahu Saura, ed. Hepatotoxicity: From genomics to in vitro and in vivo models. John Wiley & Sons, 2007.

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Tyson, Charles A. In Vitro Biological Systems. Academic Press, 1993.

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A, Tyson Charles, and Frazier John M, eds. In vitro biological systems. Academic Press, 1993.

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M, Frazier John, ed. In vitro toxicity testing: Applications to safety evaluation. Marcel Dekker, 1992.

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1937-, Cross John, and Singer Edward J. 1926-, eds. Cationic surfactants: Analytical and biological evaluation. M. Dekker, 1994.

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International Symposium on In Vitro and In Vivo Evaluation of Antifungal Agents (1985 Tokyo). In vitro and in vivo evaluation of antifungal agents. Edited by Iwata Kunio and Bossche H. van den. Elsevier, 1986.

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Ryan, Mandy. Economic evaluation of in-vitro fertilisation: Examining the benefits. Health Economics Research Unit, University of Aberdeen, 1992.

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1952-, Young David, Devane John G, and Butler Jackie, eds. In vitro-in vivo correlations. Plenum Press, 1997.

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H, Crawford Ralph, and Pacific Northwest Research Station (Portland, Or.), eds. In vitro interactions among species of Trichoderma with inference toward biological control. U.S. Dept. of Agriculture, Forest Service, Pacific Northwest Research Station, 1994.

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Book chapters on the topic "In vitro biological evaluation"

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Kocan, Richard M., and Marsha L. Landolt. "Use of Herring Embryos for In Situ and In Vitro Monitoring of Marine Pollution." In In Situ Evaluation of Biological Hazards of Environmental Pollutants. Springer US, 1990. http://dx.doi.org/10.1007/978-1-4684-5808-4_5.

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Zulkarnain, Zulkarnain, Eliyanti Eliyanti, and Budiyati Ichwan. "Evaluation of in vitro Growth and Development of Banana cv. Barangan Plantlets as Affected by Biotin Application." In Advances in Biological Sciences Research. Atlantis Press International BV, 2024. http://dx.doi.org/10.2991/978-94-6463-510-2_2.

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Faria, J. T., F. N. Ambrosio, R. A. Lombello, and C. B. Lombello. "Biological Evaluation of in vitro Cytotoxicity of Extracts of Lafoensia glyptocarpa Koehne (Lythraceae)." In IFMBE Proceedings. Springer Nature Switzerland, 2023. http://dx.doi.org/10.1007/978-3-031-49401-7_38.

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Perpetuini, David, Giacomo Pagano, Daniela Cardone, et al. "Thermographic Evaluation of Dental Implants Insertion with Different Diameters: In Vitro Comparison Between Regular and Narrow Implants." In 8th European Medical and Biological Engineering Conference. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-64610-3_126.

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Seynhaeve, Ann L. B., and Timo L. M. ten Hagen. "An In Vivo Model to Study Cell Migration in XYZ-T Dimension Followed by Whole-Mount Re-evaluation." In Cell Migration in Three Dimensions. Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-2887-4_19.

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AbstractCell migration is a very dynamic process involving several chemical as well as biological interactions with other cells and the environment. Several models exist to study cell migration ranging from simple 2D in vitro cultures to more demanding 3D multicellular assays, to complex evaluation in animals. High-resolution 4D (XYZ, spatial + T, time dimension) intravital imaging using transgenic animals with a fluorescent label in cells of interest is a powerful tool to study cell migration in the correct environment. Here we describe an advanced dorsal skinfold chamber model to study endot

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Kamalaldin, Nurulain ‘Atikah, Mariatti Jaafar, Saiful Irwan Zubairi, and Badrul Hisham Yahaya. "Physico-Mechanical Properties of HA/TCP Pellets and Their Three-Dimensional Biological Evaluation In Vitro." In Advances in Experimental Medicine and Biology. Springer International Publishing, 2017. http://dx.doi.org/10.1007/5584_2017_130.

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Yilmaz, Mustafa Abdullah, and Oguz Cakir. "Salvia (Sage) Species, a Game-Changer Bioactive Plant: Focus on Antioxidant Properties." In Natural Antioxidants and in Vitro Antioxidant Assays. Nobel Tip Kitabevleri, 2024. http://dx.doi.org/10.69860/nobel.9786053359333.4.

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The demand for natural, health-oriented food additives and components has increased, with plant-based foods rich in phytochemicals like phenolic compounds being beneficial for human health. Salvia species, the largest plant family in the Lamiaceae, contain over nine hundred species, including sage, which has numerous beneficial uses and biological properties. Sage extracts have shown antioxidant, hypoglycemic, hypolipidemic, antitumor, anticholinesterase, antimicrobial, and liver-protective properties. S. officinalis L. has been suggested to have an anti-radical effect against uranium toxicity

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Prasad, Babu R., Enda O’Connell, Terry J. Smith, Valérie A. Gérard, Yurii K. Gun’ko, and Yury Rochev. "Evaluating the Potential of Quantum Dots for In Vitro Biological Studies: Effects on Gene Expression Using Microarray Analysis." In Nanoparticles in Biology and Medicine. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-953-2_12.

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Chen, T. C., Z. Lu, and M. F. Holick. "Evaluation of the Effect of Sun-Tanning Bed Radiation on the Synthesis of Previtamin D3 and the Degradation of Vitamin D3 in an on Vitro Model." In Biologic Effects of Light, edited by Michael F. Holick and Albert M. Kligman. De Gruyter, 1992. http://dx.doi.org/10.1515/9783110856156-009.

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Patterson, Wayne R. "In Vitro Diagnostics." In Clinical Evaluation of Medical Devices. Humana Press, 1998. http://dx.doi.org/10.1007/978-1-4757-2756-2_9.

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Conference papers on the topic "In vitro biological evaluation"

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Kovacs, P. "Electrochemical Techniques for Studying the Corrosion Behavior of Metallic Implant Materials." In CORROSION 1992. NACE International, 1992. https://doi.org/10.5006/c1992-92214.

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Abstract As the biocompatibility of metallic implant materials is closely related to their corrosion behavior, the recognition of the advantages and limitations of routinely used corrosion tests is of primary importance. While electrochemical techniques provide invaluable information about the most relevant performance issues, the interpretation of the result obtained by these techniques may require more complex electrochemical considerations than usual in the case of less corrosion resistant metals and alloys. Additionally, the use of nonelectrochemical techniques such as metal ion concentrat

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Shirokova, Olesya, Petr Vasilchikov, Elizaveta Kozliaeva, Svetlana Korotchenko, and Irina Mukhina. "Biological Sex Determines Differences in Gene Expression During Replicative Aging of Glia in Vitro." In 2024 Sixth International Conference Neurotechnologies and Neurointerfaces (CNN). IEEE, 2024. http://dx.doi.org/10.1109/cnn63506.2024.10705843.

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Schmidt, C., K. Winterling, CC Heinz, et al. "4CPS-100 Quality of intratect: in vitro evaluation of biological activities." In 24th EAHP Congress, 27th–29th March 2019, Barcelona, Spain. British Medical Journal Publishing Group, 2019. http://dx.doi.org/10.1136/ejhpharm-2019-eahpconf.249.

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"Evaluation of the antibacterial effects of Capsicum annuum hydroalcoholic extract in vitro condition." In International Conference on Medicine, Public Health and Biological Sciences. CASRP Publishing Company, Ltd. Uk, 2016. http://dx.doi.org/10.18869/mphbs.2016.220.

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Catalano, Enrico. "In vitro biological validation and cytocompatibility evaluation of hydrogel iron-oxide nanoparticles." In NANOINNOVATION 2016. Author(s), 2017. http://dx.doi.org/10.1063/1.4997140.

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Wang, Mei, Piwu Li, Xin Zhang, et al. "Evaluation and study on probiotics effect of lactobacillus strains in vitro." In 2ND INTERNATIONAL CONFERENCE ON FRONTIERS OF BIOLOGICAL SCIENCES AND ENGINEERING (FSBE 2019). AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0000195.

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Silva-Júnior, Edeildo, Gabriel Passos, Matheus Gomes, et al. "Design, synthesis and in vitro biological evaluation of acrylamide derivatives against Chikungunya virus." In 5th International Electronic Conference on Medicinal Chemistry. MDPI, 2019. http://dx.doi.org/10.3390/ecmc2019-06379.

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Lee, Selene A., James R. Pinney, Elvira Khialeeva, Marvin Bergsneider, and Jack W. Judy. "Functional evaluation of magnetic microactuators for removing biological accumulation: An in vitro study." In 2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2008. http://dx.doi.org/10.1109/iembs.2008.4649311.

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Elcin, Huseyn. "FUNCTION AND SAFETY EVALUATION OF 3D TECHNOLOGY TO PREPARE BONE REPAIR BIOMATERIALS." In International Trends in Science and Technology. RS Global Sp. z O.O., 2021. http://dx.doi.org/10.31435/rsglobal_conf/28022021/7433.

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PLGA/HA composite biomaterials are prepared, and 3D printing technology is used to make bone scaffolds that can be implanted in the body. Its performance is tested by in vitro physical and biological methods, and its safety is evaluated by animal experiments. Methods: 3D printing technology was used to print the PLGA/HA composite three-dimensional stent biomaterial, and the tensile strength and bending strength of the stent material were tested with reference to GB/T1040 and GB/T9341 to verify its ability to support the proliferation and differentiation of hMSC. The biological evaluation stand

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"Evaluation of Antioxidant Activity in Vitro of Polyphenols from Toona Sinensis Seeds Using RSM Optimized Conditions." In 2017 International Conference on Materials Science and Biological Engineering. Francis Academic Press, 2017. http://dx.doi.org/10.25236/icmsbe.2017.01.

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Reports on the topic "In vitro biological evaluation"

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Swasdison, Somporn, Jariya Boonjawat, and Manit Sonsuk. Grafting of natural rubber copolymer with ethyl methacrylate by gamma irradiation for using as soft lining denture base material. Chulalongkorn University, 2006. https://doi.org/10.58837/chula.res.2006.13.

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Recently, natural rubber has been used in several medical products. The purpose of this study was to develop a soft lining material from natural latex which had been improved its physical, mechanical and biological properties. Initially, natural latex was vulcanized by gamma irradiation. The vulcanized latex was then grafted with ethyl methacrylate using gamma irradiation also. The grafted vulcanized rubber, so-called graft copolymer, was evaluated for its physical and mechanical properties as well as the cellular biocompatibility. Coe Supersoft, the commercial soft lining material, was used a

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FRIEDMANN, THOMAS A., JOHN P. SULLIVAN, DAVID A. LAVAN, DANIEL KOHANE, and JOHN P. SULLIVAN. Amorphous Diamond In Vivo and In Vitro Evaluation. Office of Scientific and Technical Information (OSTI), 2003. http://dx.doi.org/10.2172/809621.

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Reaves, Jimmy L., and Ralph H. Crawford. In vitro colony interactions among species of Trichoderma with inference toward biological control. U.S. Department of Agriculture, Forest Service, Pacific Northwest Research Station, 1994. http://dx.doi.org/10.2737/pnw-rp-474.

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Spiers, Donald, Arieh Gertler, Harold Johnson, and James Spain. An In Vitro and In Vivo Investigation of the Diverse Biological Activities of Bovine Placental Lactogen. United States Department of Agriculture, 1993. http://dx.doi.org/10.32747/1993.7568087.bard.

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In order to understand the structure-function relationship of bovine placental lactogen (bPL) and initiate production of material for in vivo testing, 28 different bPL analogues were prepared by either truncation or site-directed mutagenesis. The effect of these mutations was determined by measuring binding capacity, ability to homodimerize extracellular domains (ECDs) of several lactogenic and somatogenic receptors, and by in vitro bioassays. Two analogues were prepared in large amounts for in vivo studies. These studies (a) identified the residues responsible for the somatogenic activity of

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Fu, R. K., and G. Mazzella. Evaluation of biological conversion of coal-derived synthesis gas. Office of Scientific and Technical Information (OSTI), 1990. http://dx.doi.org/10.2172/6350011.

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Hawkins, Brian T., and Sonia Grego. A Better, Faster Road From Biological Data to Human Health: A Systems Biology Approach for Engineered Cell Cultures. RTI Press, 2017. http://dx.doi.org/10.3768/rtipress.2017.rb.0015.1706.

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Traditionally, the interactions of drugs and toxicants with human tissue have been investigated in a reductionist way—for example, by focusing on specific molecular targets and using single-cell-type cultures before testing compounds in whole organisms. More recently, “systems biology” approaches attempt to enhance the predictive value of in vitro biological data by adopting a comprehensive description of biological systems and using computational tools that are sophisticated enough to handle the complexity of these systems. However, the utility of computational models resulting from these eff

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Kerem, Zohar, Yael Vodovotz, David Bonfil, Steven J. Schwartz, and Mark Failla. Do Saponins Present in Model Systems and Legume Bread Modulate Cholesterol Absorption in vitro and in vivo? United States Department of Agriculture, 2011. http://dx.doi.org/10.32747/2011.7592656.bard.

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No abstract. The overall general goal of the research project was to provide evidence for the beneficial biological activity of saponins from edible legumes, and to incorporate them into bread hat will become a functional food. Its functionality is in its ability to attenuate the absorption of dietary lipids and cholesterol.

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Lalain, Teri A., Mark D. Brickhouse, Jerry W. Pfarr, Stanley C. Gater, James P. Hendershot, and Brent A. Mantooth. Biological-Warfare Agent Decontamination Efficacy Testing: Large-Scale Chamber mVHP (Trademark) Decontamination System Evaluation for Biological Contamination. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada472382.

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DuBose, D. A., D. M. Rufolo, and D. H. Morehouse. Evaluation of an In Vitro of Human Immune Activation Induced by Freeze-Thaw Tissue Damage. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada399591.

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Dougherty, G., D. Hadley, P. O'Connor, and J. Bottiger. Engineered Aerosol Production for Laboratory Scale Chemical / Biological Test and Evaluation. Office of Scientific and Technical Information (OSTI), 2007. http://dx.doi.org/10.2172/908081.

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