Academic literature on the topic 'In Vitro Cytotoxicity Test'

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Journal articles on the topic "In Vitro Cytotoxicity Test"

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Eskov, Andrey, Rinat Kayumov, and Anatoly Sokolov. "Dynamic, label free test for in vitro cytotoxicity." Toxicology Letters 211 (June 2012): S148. http://dx.doi.org/10.1016/j.toxlet.2012.03.539.

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Honma, Masamitsu. "Cytotoxicity measurement in in vitro chromosome aberration test and micronucleus test." Mutation Research/Genetic Toxicology and Environmental Mutagenesis 724, no. 1-2 (2011): 86–87. http://dx.doi.org/10.1016/j.mrgentox.2011.05.003.

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Groth, Thomas, Peter Falck, and Rainer-Reginald Miethke. "Cytotoxicity of Biomaterials — Basic Mechanisms and In Vitro Test Methods: A Review." Alternatives to Laboratory Animals 23, no. 6 (1995): 790–99. http://dx.doi.org/10.1177/026119299502300609.

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Biocompatibility is one of the main prerequisites for the clinical use of biomaterials. Central to the testing of biocompatibility is the estimation of cytotoxicity, which can be assessed in vitro by using a variety of different target primary cells or cell lines. The influence of toxic agents derived from biomaterials on cellular functions and cell viability can be characterised by reductions in cell adhesion, alterations in cellular morphology, reduced cellular proliferation, and cell death, demonstrated by an absence of metabolic activity, structural disintegration and cell lysis. A brief r
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Spielmann, Horst, Manfred Liebsch, Sabine Kalweit, et al. "Results of a Validation Study in Germany on Two in Vitro Alternatives to the Draize Eye Irritation Test, the HET-CAM Test and the 3T3 NRU Cytotoxicity Test." Alternatives to Laboratory Animals 24, no. 5 (1996): 741–858. http://dx.doi.org/10.1177/026119299602400511.

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During 1988–1992, a validation study was carried out in Germany on the capacity of two in vitro tests to replace the Draize eye test for severely eye irritating chemicals, namely, the hen's egg chorio-allantoic membrane (HET-CAM) test and the 3T3 cell neutral red uptake (NRU) cytotoxicity test, which had shown promising results in an earlier test development project. The formal validation study, which was coordinated by Centre for Documentation and Evaluation of Alternative Methods to Animal Experiments (ZEBET) and funded by the German Department of Research and Technology (BMBF), was conducte
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Seibert, Hasso, Michael Gulden, Marike Kolossa, and Gabi Schepers. "Evaluation of the Relevance of Selected In Vitro Toxicity Test Systems for Acute Systemic Toxicity." Alternatives to Laboratory Animals 20, no. 2 (1992): 240–45. http://dx.doi.org/10.1177/026119299202000211.

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Progress in the implementation of in vitro methods in testing procedures for non-genetic toxicity is limited by poor or missing validation of the various approaches. Many efforts have focused on determinations of general cytotoxicity in vitro using proliferating, non-differentiated cell lines. The aim of our present studies is to evaluate the relevance to acute systemic toxicity of three in vitro systems using differentiated mammalian cells (bovine spermatozoa, primary cultured rat hepatocytes, primary cultured rat skeletal muscle cells) and also one in vitro system which uses a continuous cel
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Kumar, M. Praveen, Shravan Kini, M. S. Prathap, Aravind R. Kudva, Aboobacker Sidheeque, and Ashwini Prabhu. "In vitro cytotoxicity evaluation of endodontic irrigants combined with cationic peptide." Journal of Conservative Dentistry and Endodontics 28, no. 1 (2025): 84–89. https://doi.org/10.4103/jcde.jcde_690_24.

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Abstract Aim: The aim of this study was to assess the cytotoxicity of endodontic irrigants 2% chlorhexidine (CHX) and ethylenediaminetetraacetic acid (EDTA) combined with cationic peptide DJK-5 on L929 mouse subcutaneous fibroblast cells. Subjects and Methods: L929 cells were cultured and treated with 2% CHX, 2% CHX + DJK-5, 8.5% EDTA, 8.5% EDTA + DJK-5, and DJK-5 alone (DJK-5 peptide concentration–10 μg/mL) for 24 and 48 h. The cytotoxicity of the endodontic irrigants was determined using methyl thiazolyl tetrazolium assay and Live/Dead assay using acridine orange and ethidium bromide dual fl
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Srivastava, Sabita, Stephen D. Gorham, and James M. Courtney. "Screening of in vitro cytotoxicity by the adhesive film test." Biomaterials 11, no. 2 (1990): 133–37. http://dx.doi.org/10.1016/0142-9612(90)90129-e.

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Fang-gang, Liao, and Wei Yi. "Cytotoxicity test of nickel-containing ceramic metal alloys in vitro." Journal of Dentistry 19, no. 2 (1991): 132. http://dx.doi.org/10.1016/0300-5712(91)90112-c.

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MAZLUMOGLU, Busra Sahin. "In Vitro Cytotoxicity Test Methods: MTT and Neutral Red Uptake." Pharmata 3, no. 2 (2023): 50–53. http://dx.doi.org/10.5152/pharmata.2023.1287964.

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Hanan, M. Ali, Saad Abdul Samad Baryham, Loay Mohammed Noha, Shaheen Hammadi Saad, and Salim Temma Asawer. "Analytical study and cytotoxicity test of azo dye in vitro." Journal of Wildlife and Biodiversity 7, Special Issue (2023): 471–77. https://doi.org/10.5281/zenodo.10246975.

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Analytical study of the azo dye (HA) showed that it can be affected by their solubility and the dielectric constant (D) of solvents. The MTT assay was used to test the effectiveness of HA against MCF-7 cell line, which indicated their sensible inhibition rates in contrast with the control (C). The assay also showed the great ability of the (HA) azo dye in destroying the MDA-MB231 cells and how it affected their viability%, which was better than their ability against the MCF-7 cell line. And this activity increased with the increase of their concentration. Statistical analysis gave P<0.05. F
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Dissertations / Theses on the topic "In Vitro Cytotoxicity Test"

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Srikanth, Madhulika. "In vitro cytotoxicity tests of nanomaterials on 3T3 and l929 cancerous cells." Thesis, Wichita State University, 2012. http://hdl.handle.net/10057/5422.

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In this MS thesis, cytotoxicity tests of various nanomaterials, which have commercial applications and involve a contact with human body, were performed at different conditions. The nanomaterials used for the experiments included pristine 100 ply carbon nanowire, graphene nanoflakes, multiwall carbon nanotubes, nanoclay and C60 (buckyball or fullerene). The nanomaterials cytotoxicities were calculated and compared to each other using human and mice fibroblast cancerous cells (3T3 and L929 resp.). The in vitro MTT Assay was used as the testing method because of its simplicity and reliability. T
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Cruz, Aurea Silveira. "Teste de citotoxicidade \'in vitro\' como alternativa ao teste \'in vivo\' de Draize na avaliação de produtos cosméticos." Universidade de São Paulo, 2003. http://www.teses.usp.br/teses/disponiveis/9/9139/tde-03082007-170357/.

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Os procedimentos descritos por Draize são a base dos testes de irritação ocular e cutânea adotados internacionalmente para avaliar produtos e substâncias. Entretanto, eles têm sido criticados por motivos éticos, devido à crueldade com os animais e, por isso, metodologias alternativas têm sido estudas para avaliar a toxicidade de produtos que entram em contato com o ser humano. Sendo assim, um estudo comparativo foi realizado entre testes de irritação ocular, cutânea e mucosa oral usando coelhos e testes in vitro pelos métodos de difusão em ágar e de captura do vermelho neutro, ambos usando as
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Azevedo, Janice Campos de. "Avaliação de metodologia alternativa in vitro ao teste de irritação ocular de Draize." Universidade de São Paulo, 1998. http://www.teses.usp.br/teses/disponiveis/9/9139/tde-25102011-100819/.

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Para a avaliação do potencial irritante de substâncias aplicadas topicamente tem-se utilizado metodologias que baseiam nos estudos de Draize, onde preconiza-se o uso de animais. Devido à forte oposição a estes testes, intensa tem sido a busca por métodos alternativos visando diminuir ou eliminar a utilização de animais. Este estudo avaliou o potencial irritante de diversas substâncias através de duas metodologias: o teste in vivo , empregando metodologia oficial do Food and Drug Administration (FDA), onde utiliza-se coelhos e o teste de citotoxicidade in vitro - método de difusão em camada de
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Amaral, Mauricio Bordini do. "Citotoxidade in vitro e biocompatibilidade in vivo de compósitos a base de hidroxiapatita, colágeno e quitosana." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/82/82131/tde-30072007-163145/.

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Na engenharia de tecidos os biomateriais são usados tanto para induzir a formação óssea no tecido adjacente quanto agir como matriz temporária de células e outros agentes. Compósitos biodegradáveis a base de hidroxiapatita, colágeno e quitosana foram preparados como arcabouços para permitir a regeneração óssea. Este estudo teve como objetivo avaliar a toxicidade celular in vitro de novos compósitos de substituição óssea e o seu comportamento biológico após implantação subcutânea no processo de remodelação e cicatrização tecidual. Foram confeccionadas mantas a base de hidroxiapatita (HA), obtid
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Manuel, Nathalie. "Etude "in vitro" de la libération des sérine-estérases par des cellules effectrices cytotoxiques humaines au moyen d'un test enzymatique." Paris 5, 1993. http://www.theses.fr/1993PA05P042.

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Bonatto, Liliane da Rocha [UNESP]. "Biocompatibilidade de primers e adesivo utilizados na confecção de próteses maxilofaciais implantorretidas: análise in vitro." Universidade Estadual Paulista (UNESP), 2015. http://hdl.handle.net/11449/134194.

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Made available in DSpace on 2016-02-05T18:30:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-06-15. Added 1 bitstream(s) on 2016-02-05T18:34:15Z : No. of bitstreams: 1 000857711.pdf: 1685122 bytes, checksum: 06044cf174850099dc014984d0007cc8 (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>A prótese bucomaxilofacial implantorretida pode ser suportada por pele ou por mucosa. Subprodutos dos materiais utilizados na confecção destas próteses podem atuar como irritantes ou causadores de reações alérgicas a tais tecidos. A proposta do presente estudo foi av
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Bonatto, Liliane da Rocha. "Biocompatibilidade de primers e adesivo utilizados na confecção de próteses maxilofaciais implantorretidas : análise in vitro /." Araçatuba, 2015. http://hdl.handle.net/11449/134194.

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Orientadora: Daniela Micheline dos Santos<br>Coorientador: Marcelo Coelho Goiato<br>Banca: Marcela Fillié Haddad<br>Banca: Sandra Helena Penha de Oliveira<br>Resumo: A prótese bucomaxilofacial implantorretida pode ser suportada por pele ou por mucosa. Subprodutos dos materiais utilizados na confecção destas próteses podem atuar como irritantes ou causadores de reações alérgicas a tais tecidos. A proposta do presente estudo foi avaliar a citotoxicidade de primers e adesivo utilizados na confecção de próteses maxilofaciais retidas por implantes, por meio da análise da proliferação celular e da p
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Roux, Hélène. "Optimisation d'un test in vitro de la cytocompatibilité des biomatériaux en culture organotypique." Compiègne, 1993. http://www.theses.fr/1993COMPD567.

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L'essor des biomatériaux et leur utilisation dans le domaine médical ainsi que le développement des méthodes alternatives aux tests in vivo sont à l’origine des techniques permettant de mesurer la cytocompatibilité et la cytotoxicité des matériaux. Un modèle base sur la culture organotypique, permet d'évaluer la cytocompatibilité et la cytotoxicité des matériaux au contact des tissus. Il repose sur la mesure de trois propriétés : la multiplication cellulaire, la migration cellulaire et l'adhésion des cellules au substrat. Ce travail a eu pour objet l'optimisation et la validation du modèle. L'
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Figarol, Agathe. "Toxicité in vitro et propriétés physico-chimiques de nanotubes de carbone." Thesis, Saint-Etienne, EMSE, 2014. http://www.theses.fr/2014EMSE0764/document.

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Les propriétés exceptionnelles des nanotubes de carbone (CNT) attirent de nombreux industriels dans les domaines de la microélectronique, des matériaux ou de la nanomédecine. Néanmoins, le risque sanitaire lié à ce nanomatériau reste encore mal compris. Des profils toxicologiques différents, dépendant des caractéristiques physico-Chimiques des CNT, ont été mis en évidence. Une approche « safer by design » est proposée, afin d’identifier les paramètres pouvant, dès la conception des CNT, pour limiter le risque sanitaire. Dans ce contexte, cette thèse avait pour objectif d’étudier l’impact sur l
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Mazurek, Nicole. "Untersuchungen zur Genexpression und Differenzierung muriner embryonaler Stammzellen in vitro zur Prädiktion eines embryotoxischen Potentials ausgewählter Chemikalien." Master's thesis, Universität Potsdam, 2007. http://opus.kobv.de/ubp/volltexte/2013/6891/.

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Der Embryonale Stammzelltest (EST) ist ein validierter In-vitro-Embryotoxizitätstest, der zur Untersuchung embryotoxischer Wirkungen von Chemikalien eingesetzt werden kann. Während des zehntägigen Differenzierungsassays differenzieren sich die pluripotenten murinen embryonalen Stammzellen (ES-Zellen) der Linie D3 in vitro in spontan kontrahierende Herzmuskelzellen. Dabei rekapitulieren sie Prozesse der frühen Embryogenese in vivo. Ein Zytotoxizitätsassay mit D3-Zellen und ausdifferenzierten, adulten 3T3-Maus-Fibroblasten dient der Ermittlung allgemeiner zytotoxischer Effekte und unterschiedlic
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Books on the topic "In Vitro Cytotoxicity Test"

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Organisation for economic co-operation and development. Test No. 476: In vitro Mammalian Cell Gene Mutation Test. OECD Publishing, 1997.

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International Conference on In Vitro Cytotoxicity Mechanisms (1999 Rome, Italy). International Conference on in vitro cytotoxicity mechanisms, Istituto Superiore di Sanità, Rome, January 25-27, 1999: Abstract book. Istituto Superiore di Sanità, 1999.

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Partridge, Malcolm Bruce Richard. A study of the In Vitro cytotoxicity of alkylaminoanthraquinone antitumour agents based on doxorubicin and mitozantrone. Leicester Polytechnic, 1987.

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Information, LLC Kalorama. The worldwide market for in vitro diagnostic test. Kalorama Information, 2002.

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Motoi, Ishidate, ed. Data book of chromosomal aberration test in vitro. Elsevier, 1988.

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MacGregor, Karen Jaon. Design and in vitro cytotoxicity evaluation of a thermoreversible gel for the topical delivery of anticancer drugs. De Montfort University, 1994.

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Kristensen, Jo⁺rgen. In vitro analysis of cytotoxic drug activity in acute leukemia using the fluorometric microculture cytotoxicity assay (FMCA). Acta Universitatis Upsaliensis, 1995.

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Kannegiesser, H. J. Conception in the test tube: The IVF story : how Australia leads the world. Macmillan, 1988.

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Luz, Claudio, and United States. Environmental Protection Agency, eds. Implementing in vitro test models in the hazard identification and risk assessment process. U.S. Environmental Protection Agency, 1992.

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Mansour, Mansour. Entwicklung eines standardisierten in vitro-Test-Systems zur Prüfung der Hämokompatibilität von Biomaterialien. [s.n.], 1998.

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Book chapters on the topic "In Vitro Cytotoxicity Test"

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Blein-Sella, Odile, and Monique Adolphe. "SIRC Cytotoxicity Test." In In Vitro Toxicity Testing Protocols. Humana Press, 1995. http://dx.doi.org/10.1385/0-89603-282-5:161.

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Liebsck, H. M., and Horst Spielmann. "Balbh 3T3 Cytotoxicity Test." In In Vitro Toxicity Testing Protocols. Humana Press, 1995. http://dx.doi.org/10.1385/0-89603-282-5:177.

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Clothier, Richard H. "The FRAME Cytotoxicity Test (Kenacid Blue)." In In Vitro Toxicity Testing Protocols. Humana Press, 1995. http://dx.doi.org/10.1385/0-89603-282-5:109.

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Bianchi, Vera. "V79 Cytotoxicity Test for Membrane Damage." In In Vitro Toxicity Testing Protocols. Humana Press, 1995. http://dx.doi.org/10.1385/0-89603-282-5:151.

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Lewis, E., and M. D. Lipkin. "Failure of Attapulgite to Produce Tumors: Prediction of this Result by in Vitro Cytotoxicity test." In In Vitro Effects of Mineral Dusts. Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-70630-1_71.

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Popper, H. H., M. Ratschek, E. Grygar, et al. "Cytotoxicity of chromium compounds: Comparison of in vitro and in vivo tests." In Environmental Hygiene II. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-46712-7_17.

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Lock, Richard B. "Determinants of Etoposide Cytotoxicity in Vitro." In Anticancer Drug Discovery and Development: Natural Products and New Molecular Models. Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2610-0_16.

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Fiskesjö, Geirid. "Allium Test." In In Vitro Toxicity Testing Protocols. Humana Press, 1995. http://dx.doi.org/10.1385/0-89603-282-5:119.

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Ribeiro, Arthur B., Juliana G. F. Silva, Lucas N. F. Trevizan, Hernane S. Barud, Flávia A. Resende, and Denise C. Tavares. "In Vitro Cytotoxicity Testing of Food Packaging." In Food Packaging Materials. Springer US, 2024. http://dx.doi.org/10.1007/978-1-0716-3613-8_7.

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Vallyathan, V., N. Hahon, J. Booth, D. Schwegler, and M. Sepulveda. "Cytotoxicity of Native-and Surface-Modified Asbestos." In In Vitro Effects of Mineral Dusts. Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-70630-1_19.

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Conference papers on the topic "In Vitro Cytotoxicity Test"

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Andrew, Andrew, Irma Ervina, and Harry Agusnar. "In Vitro Chitosan Hydrogel Based Tetracycline Cytotoxicity Test on Fibroblast Viability." In 11th International Dentistry Scientific Meeting (IDSM 2017). Atlantis Press, 2018. http://dx.doi.org/10.2991/idsm-17.2018.36.

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Rasni, Hilma, Irma Ervina, and Syafruddin Ilyas. "In Vitro Chitosan Hydrogel Based Metronidazole Cytotoxicity Test on 3t3 Fibroblast Viability." In 11th International Dentistry Scientific Meeting (IDSM 2017). Atlantis Press, 2018. http://dx.doi.org/10.2991/idsm-17.2018.44.

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Asmatulu, R., A. Garikapati, H. E. Misak, Z. Song, S. Y. Yang, and P. Wooley. "Cytotoxicity of Magnetic Nanocomposite Spheres for Possible Drug Delivery Systems." In ASME 2010 International Mechanical Engineering Congress and Exposition. ASMEDC, 2010. http://dx.doi.org/10.1115/imece2010-40269.

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Cytotoxicity test is a rapid and standardized in vitro method to determine the harmful effects of materials used for biomedical purposes, such as drug carriers, implants and their coatings, biosensors and surgical/medical devices. In the present study, sol-gel driven nickel ferrite (NiFe2O4) and cobalt ferrite (CoFe2O4) nanoparticles (10–25 nm) at different concentrations were incorporated into biodegradable polymer, poly(lactic-co-glycolic acid) (PLGA), using oil-in-oil emulsion/solvent evaporation technique, and then the cytotoxicity of magnetic nanocomposite spheres was characterized using
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Rosli, Nur Shafawati binti, Azhar Abdul Rahman, Azlan Abdul Aziz, and Shaharum Shamsuddin. "Determining the size and concentration dependence of gold nanoparticles in vitro cytotoxicity (IC50) test using WST-1 assay." In NATIONAL PHYSICS CONFERENCE 2014 (PERFIK 2014). AIP Publishing LLC, 2015. http://dx.doi.org/10.1063/1.4915189.

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Zheng, X. B., and C. X. Ding. "Bonding Strength Test and Biological Evaluation of Plasma Sprayed HA-Based Composite Coatings." In ITSC2001, edited by Christopher C. Berndt, Khiam A. Khor, and Erich F. Lugscheider. ASM International, 2001. http://dx.doi.org/10.31399/asm.cp.itsc2001p1017.

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Abstract To improve the bonding strength of HA coating, several HA-based composite coatings (HA/Ti, HA/ZrO2 HA/ZrO2SiO2 and HA/NiCr composite coatings) have been fabricated via atmospheric plasma spraying. The bonding strengths of fabricated specimens were tested by ASTM C-633 method. The bioactivity of composite coatings was evaluated by examining carbonate-containing apatite formation on their surfaces in simulated body fluid (SBF). In vitro cell cultures were carried out to examine the biocompatibihty of composite coatings. The results obtained revealed that the addition of metal or ceramic
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Akpinar, Ayse Nur, Selvi Secil Sahin, Büşra Moran Bozer, Aziz Tekin, and Cansu Ekin Gumus-Bonacına. "Effect of Food Emulsions on the Cytotoxicity of 3-chloropropane-1,2-diol Esters." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/emiq3563.

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3-Chloropropane-1,2-diol (3-MCPD) esters are food processing contaminants, and are known to be potentially carcinogenic. The main purpose of this study was to determine whether the emulsion technique increases the absorption of this contaminant, and to develop strategies to reduce their absorption. 3-MCPD ester contents in edible oils (hazelnut, walnut, sunflower, soybean, corn, and olive oil) were determined. Refined olive oil contained the highest 3-MCPD ester level (1.7749 ± 0.1262 mg/kg). Then, emulsions (fine, medium, coarse) were prepared with 0.15-2% emulsifier (whey protein isolate) an
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Ma, Liang, Jeremy Barker, Changchun Zhou, Biaoyang Lin, and Wei Li. "A Perfused Two-Chamber System for Anticancer Drug Screening." In ASME 2010 International Manufacturing Science and Engineering Conference. ASMEDC, 2010. http://dx.doi.org/10.1115/msec2010-34326.

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A cell culture microfluidic device has been developed to test the cytotoxicity of anticancer drugs while reproducing multi-organ interactions in vitro. Cells were cultured in separate chambers representing the liver and tumor. The two chambers were connected through a channel to mimick the blood flow. Glioblastoma (GBM) cancer cells (M059K) and hepatoma cells (HepG2) were cultured in the tumor and the liver chambers, respectively. The cytotoxic effect of cancer treatment drug Temolozomide (TMZ) was tested using this two chamber system. The experimental results showed that with the liver cells,
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Sendi, Rabab Khalid, Shahrom Mahmud, Ayman Munshi, and Azman Seeni. "In vitro cytotoxicity tests of ZnO‐Bi2O3‐Mn2O3-based varistor fabricated from ZnO micro and nanoparticle powders on L929 mouse cells." In 3RD INTERNATIONAL CONFERENCE ON FUNDAMENTAL AND APPLIED SCIENCES (ICFAS 2014): Innovative Research in Applied Sciences for a Sustainable Future. AIP Publishing LLC, 2014. http://dx.doi.org/10.1063/1.4898539.

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Ma, Liang, Lei Gao, Yichen Luo, et al. "Flow Analysis of a Porous Polymer-Based Three-Dimensional Cell Culture Device for Drug Screening." In ASME 2018 13th International Manufacturing Science and Engineering Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/msec2018-6313.

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A porous polymer-based three-dimensional (3D) cell culture device has been developed as an in vitro tissue model system for the cytotoxicity of anticancer drug test. The device had two chambers connected in tandem, each loaded with a 3D scaffold made of highly biocompatible poly (lactic acid) (PLA). Hepatoma cells (HepG2) and glioblastoma multiforme (GBM) cancer cells were cultured in the two separate porous scaffolds. A peristaltic pump was adopted to realize a perfusion cell culture. In this study, we focus on cell viability inside the 3D porous scaffolds under flow-induced shear stress effe
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Zhang, Qingwei, Wei Zhang, Donggang Yao, David M. Wootton, Peter I. Lelkes, and Jack G. Zhou. "Micro-Porous PLLA Scaffolds for Orthopedic Surgical Fixation Devices." In ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13166.

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Anterior cruciate ligament (ACL) reconstructive surgery is a major health concern world-wide because of a large aging population and increased occurrence of sport-related injuries. Tissue engineering is a rapidly growing interdisciplinary field that offers a promising new approach for ACL repair. The aim of this project is to explore novel “smart” surgical fixation devices that not only secure a graft in place without strength failure, but also incorporate and release bioactive materials, intended to promote bone tissue growth. In order to facilitate bioactive reagent release, biopolymeric sca
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Reports on the topic "In Vitro Cytotoxicity Test"

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Eldar, Avigdor, and Donald L. Evans. Streptococcus iniae Infections in Trout and Tilapia: Host-Pathogen Interactions, the Immune Response Toward the Pathogen and Vaccine Formulation. United States Department of Agriculture, 2000. http://dx.doi.org/10.32747/2000.7575286.bard.

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In Israel and in the U.S., Streptococcus iniae is responsible for considerable losses in various fish species. Poor understanding of its virulence factors and limited know-how-to of vaccine formulation and administration are the main reasons for the limited efficacy of vaccines. Our strategy was that in order to Improve control measures, both aspects should be equally addressed. Our proposal included the following objectives: (i) construction of host-pathogen interaction models; (ii) characterization of virulence factors and immunodominant antigens, with assessment of their relative importance
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Barrows, Louis R. In-Vitro Cytotoxicity Screening of Plant Extracts. Defense Technical Information Center, 2001. http://dx.doi.org/10.21236/ada396772.

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Barrows, Louis R. In-Vitro Cytotoxicity Screening of Plant Extracts. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada410231.

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Barrows, Louis R. In-Vitro Cytotoxicity Screening of Plant Extracts. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada417374.

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กาญจนบุษย์, เถลิงศักดิ์, กุลวรา เมฆสวรรค์, อังคณา ตันติธุวานนท์, วิภาวี กิตติโกวิท, พรทิพย์สวรรค์ นวลทอง та พรเพ็ญ พนมวัลย์. การพัฒนาและการศึกษาความเป็นไปได้ในการนำน้ำตาลเชิงซ้อน-แคลวิตินมาผลิตเป็นน้ำยาฟอกไตทางช่องท้องทดแทนน้ำยาฟอกไตมาตรฐาน. คณะแพทยศาสตร์ จุฬาลงกรณ์มหาวิทยาลัย, 2010. https://doi.org/10.58837/chula.res.2010.17.

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Background. The optimal formula of calvitrin based peritoneal dialysis was composing of calvitrin 6.25 g LL~:: electrolytes such as sodium chloride 540 g, sodium lactate 448 mg, calcium chloride 25.7mg and magnesium chloride 5.08 mg Methods. In vitro studies; the cytotoxicity was investigated. Human peritoneal mesothelial cells (HPMC) were isolated and characterized as described in tetail elsewhere (29). Cells were depleated serum and treated with 15% Cal-PD, 7.5% lcodextrin, 1.5% Dextose and media controls for 36 hrs. Cells morphology changes were examined under microscopy. The results found
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Guzman, Juantia J., Clark L. Gross, William J. Smith, and Susan A. Kelly. In Vitro Cytotoxicity Assays of Human Epidermal Keratinocytes in Culture Exposed to Sulfur Mustard. Defense Technical Information Center, 2000. http://dx.doi.org/10.21236/ada390628.

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Ross, A. C. A Combined Nutritional and Immunological Intervention to Activate Natural Cytotoxicity Against Breast Cancer Cells In Vitro and In Vivo. Defense Technical Information Center, 2011. http://dx.doi.org/10.21236/ada599265.

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Lertchirakarn, Veera, and Prasit Pavasant. The effects of fluocinolone acetonide on human cultured dental pulp cell in vitro. Chulalongkorn University, 2008. https://doi.org/10.58837/chula.res.2008.15.

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The purpose of treatment of pulpal exposure is to preserve vitality, healthy and promote healing of exposed pulp tissue. Fluocinolone acetonide (FA) may have a potential to promote tissue healing. The aim of this study was therefore to investigate the effects of FA on human cultured dental pulp cell in vitro. The MTT assay was performed to examine both cytotoxicity and prolifration of FA at 24, 48 and 72 hours. The results revealed that FA (0.1 to 50 [mu]M) had no cytotoxicity effect. In addition, these doses also stimulated cell proliferation. There was a significant increase of cell prolifer
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Voudouris, P., and T. J. Verkleij. In vitro skin irritation test with Amino acid zootechnical mixture using a human skin model. Wageningen Food & Biobased Research, 2022. http://dx.doi.org/10.18174/581504.

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Voudouris, P., and T. J. Verkleij. In vitro skin corrosion test with an Amino acid zootechnical mixture using a human skin model. Wageningen Food & Biobased Research, 2022. http://dx.doi.org/10.18174/576311.

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